GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **51 - 75** of **1070** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism
VEGFA-VEGFR2 Pathway	Abl interactor 1 Abl-interactor 2 Actin-binding protein WASF1 Adapter molecule crk BAR/IMD domain-containing adapter protein 2 BRICK1 subunit of SCAR/WAVE actin nucleating complex Breast cancer anti-estrogen resistance protein 1 Cell division control protein 42 homolog Cytochrome b-245 heavy chain Cytochrome b-245 light chain Cytoplasmic FMR1-interacting protein Cytoplasmic FMR1-interacting protein Cytoplasmic protein Cytoplasmic protein Engulfment and cell motility 1 Engulfment and cell motility 2 Focal adhesion kinase 1 Heat shock protein HSP 90-alpha Heat shock protein beta-1 Integrin beta-3 Integrin subunit alpha V MAP kinase-activated protein kinase 3 MAPK activated protein kinase 2 Mapk11 protein Mitogen-activated protein kinase 12 Mitogen-activated protein kinase 13 Mitogen-activated protein kinase 14 NCK associated protein 1 like Nck-associated protein 1 Neutrophil cytosol factor 2 Neutrophil cytosolic factor 1 Neutrophil cytosolic factor 4 Paxillin Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Protein-tyrosine kinase 2-beta Proto-oncogene tyrosine-protein kinase Src Proto-oncogene vav Ras-related C3 botulinum toxin substrate 1 Rho-associated protein kinase 1 Rho-associated protein kinase 2 SH2 domain containing 2A SH2 domain containing adaptor protein B SHC-transforming protein 2 Serine/threonine-protein kinase PAK 2 Transforming protein RhoA Tyrosine-protein kinase Fyn Vascular endothelial growth factor A Vascular endothelial growth factor receptor 2 Vav guanine nucleotide exchange factor 2 Vav guanine nucleotide exchange factor 3 Wiskott-Aldrich syndrome protein family member Wiskott-Aldrich syndrome protein family member cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta receptor protein-tyrosine kinase	A0A0G2K344 A0A8I5ZLD3 A0A8I5ZNF3 A0A8I5ZPB5 A0A8I6AH32 A0A8I6AHL8 A7E3N2 B2RZ33 D3ZN31 D3ZUP5 D3ZY46 D3ZYG0 D4A3M8 D4A3U7 D4A8H8 E9PSY0 F1LZX9 F1M707 G3V982 M0R7F3 O08775 O35346 O70142 P16612 P27791 P42930 P54100 P55161 P61589 P68182 P70600 P70618 P82995 Q5BJU7 Q5FWU0 Q5I0Q2 Q62737 Q62844 Q62868 Q63538 Q63644 Q63767 Q63768 Q63787 Q63788 Q64303 Q66H76 Q66H84 Q6GMN2 Q6RUV5 Q80ZF4 Q8CFN2 Q8R2H2 Q9ERL1 Q9QZM5 Q9WTY9 Q9WUD9 Q9Z1L0	Abi1 Abi2 Arha Arha2 Axl Baiap2 Bcar1 Brk1 Cas Cdc42 Crk Crkas Crko Csbp1 Csbp2 Cyba Cybb Cyfip1 Cyfip2 Elmo1 Elmo2 Fak Fak1 Fak2 Flk1 Fyn Hem2 Hsp27 Hsp86 Hsp90aa1 Hspb1 Hspca Itgav Itgb3 Kdr Mapk11 Mapk12 Mapk13 Mapk14 Mapkapk2 Mapkapk3 Nap1 Ncf1 Ncf2 Ncf4 Nck1 Nck2 Nckap1 Nckap1l Pak2 Pik3ca Pik3cb Pik3r1 Pik3r2 Pkacb Prkaca Prkacb Ptk2 Ptk2b Pxn Pyk2 Rac Rac1 Rhoa Rock1 Rock2 Sapk3 Sck Sh2d2a Shb Shc2 Src Vav Vav1 Vav2 Vav3 Vegf Vegfa Wasf1 Wasf2 Wasf3 Wave1	Rattus norvegicus (Norway rat)
eNOS activation	Acyl-protein thioesterase 1 Calmodulin-3 Caveolin-1 Cytoglobin Heat shock protein HSP 90-alpha N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 Nitric oxide synthase 3 RAC-alpha serine/threonine-protein kinase Sepiapterin reductase	O08557 P0DP31 P18297 P41350 P47196 P70470 P82995 Q62600 Q921A4	Akt1 Apt1 CaMIII Calm3 Cam3 Camc Cav Cav1 Cygb Ddah Ddah1 Hsp86 Hsp90aa1 Hspca Lypla1 Nos3 Spr Stap	Rattus norvegicus (Norway rat)
Removal of aminoterminal propeptides from gamma-carboxylated proteins	Coagulation factor IX Coagulation factor VII Coagulation factor X Furin Growth arrest-specific protein 6 Osteocalcin Protein Z, vitamin K-dependent plasma glycoprotein Prothrombin Vitamin K-dependent protein C Vitamin K-dependent protein S	G3V8K8 P04640 P16296 P18292 P23377 P31394 P53813 Q63207 Q63772 Q8K3U6	Bglap Bglap2 Cf9 F10 F2 F7 F9 Fur Furin Gas6 Pcsk3 Proc Pros Pros1 Proz	Rattus norvegicus (Norway rat)
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA	14-3-3 protein beta/alpha 5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase 5'-3' exoribonuclease 1 DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease Exosome complex component RRP45 Exosome component 1 Exosome component 2 Exosome component 4 Exosome component 5 Exosome component 6 M7GpppN-mRNA hydrolase-like MAPK activated protein kinase 2 Ribosomal RNA-processing protein 40 Ribosomal RNA-processing protein 42 Ribosomal RNA-processing protein 43 Transportin 1 mRNA decay activator protein ZFP36	A0A0G2QC37 A0A8I5ZNY7 A0A8I6GHQ8 D3ZBP3 D3ZT51 D3ZW38 D4A4Y0 D4ABN8 D4AE80 D4AE98 F1LQP9 F7EPZ4 M0RDC9 P35213 P47973 Q4QR75 Q80ZF4	Dcp1a Dcp2 Dis3 Exosc1 Exosc2 Exosc3 Exosc4 Exosc5 Exosc6 Exosc7 Exosc8 Exosc9 LOC103690064 LOC679140 Mapkapk2 Tis11 Tnpo1 Ttp Xrn1 Ywhab Zfp36	Rattus norvegicus (Norway rat)
MET receptor recycling	ADP-ribosylation factor 6 ADP-ribosylation factor-binding protein GGA3 Adapter molecule crk Crk-like protein GRB2-associated binding protein 1 Growth factor receptor-bound protein 2 Hepatocyte growth factor receptor Hepatocyte growth factor Ras-related protein Rab-4A Ras-related protein Rab-4B	A0A0G2JV04 D3ZAL7 P05714 P17945 P51146 P62332 P62994 P97523 Q5U2U2 Q63768	Arf6 Ash Crk Crkl Crko Gab1 Gga3 Grb2 Hgf Met Rab4 Rab4a Rab4b	Rattus norvegicus (Norway rat)
Xenobiotics	Aryl hydrocarbon receptor nuclear translocator 2 Aryl hydrocarbon receptor nuclear translocator Aryl hydrocarbon receptor repressor Aryl hydrocarbon receptor Cytochrome P450 1A1 Cytochrome P450 2A1 Cytochrome P450 2A2 Cytochrome P450 2A3 Cytochrome P450 2C26-like Cytochrome P450 2C6 Cytochrome P450 2D4 Cytochrome P450 2E1 Cytochrome P450 2F2 Cytochrome P450 2J3 Cytochrome P450 3A18 Cytochrome P450 3A1 Cytochrome P450 3A2 Cytochrome P450 3A9 Cytochrome P450 3A Cytochrome P450, family 2, subfamily j, polypeptide 16 Cytochrome P450, family 2, subfamily w, polypeptide 1 Cytochrome P450 Cytochrome P450	A0A0G2JTQ9 A0A0G2K5K4 A0A0G2KAI3 A0A8I6AFV7 D4A820 G3V9D2 O35293 P00185 P04800 P05178 P05182 P05183 P11711 P15149 P20812 P41738 P41739 P51538 P51590 Q64581 Q64680 Q75NT5 Q78E60	Ahr Ahrr Arnt Arnt2 Cyp1a-1 Cyp1a1 Cyp2a-1 Cyp2a-2 Cyp2a-3 Cyp2a1 Cyp2a2 Cyp2a3 Cyp2a3a Cyp2b21 Cyp2c-6 Cyp2c6 Cyp2c66 Cyp2d-18 Cyp2d-4 Cyp2d18 Cyp2d4 Cyp2e Cyp2e-1 Cyp2e1 Cyp2f2 Cyp2f4 Cyp2j16 Cyp2j3 Cyp2j9 Cyp2s1 Cyp2w1 Cyp3a-1 Cyp3a-2 Cyp3a1 Cyp3a11 Cyp3a13 Cyp3a18 Cyp3a2 Cyp3a62 Cyp3a9 LOC100912265	Rattus norvegicus (Norway rat)
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA	14-3-3 protein beta/alpha 5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase 5'-3' exoribonuclease 1 DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease Exosome complex component RRP45 Exosome component 1 Exosome component 2 Exosome component 4 Exosome component 5 Exosome component 6 M7GpppN-mRNA hydrolase-like MAPK activated protein kinase 2 RAC-alpha serine/threonine-protein kinase Ribosomal RNA-processing protein 40 Ribosomal RNA-processing protein 42 Ribosomal RNA-processing protein 43 mRNA decay activator protein ZFP36L1	A0A0G2QC37 A0A8I5ZNY7 A0A8I6GHQ8 D3ZBP3 D3ZT51 D3ZW38 D4A4Y0 D4ABN8 D4AE80 D4AE98 F7EPZ4 M0RDC9 P17431 P35213 P47196 Q4QR75 Q80ZF4	Akt1 Brf1 Cmg1 Dcp1a Dcp2 Dis3 Exosc1 Exosc2 Exosc3 Exosc4 Exosc5 Exosc6 Exosc7 Exosc8 Exosc9 LOC103690064 LOC679140 Mapkapk2 Tis11b Xrn1 Ywhab Zfp36l1	Rattus norvegicus (Norway rat)
Regulation of HSF1-mediated heat shock response	14-3-3 protein epsilon Active regulator of SIRT1 Aladin WD repeat nucleoporin BAG cochaperone 2 BAG cochaperone 4 BAG family molecular chaperone regulator 1 BAG family molecular chaperone regulator 5 DnaJ heat shock protein family (Hsp40) member B1 DnaJ homolog subfamily B member 6 DnaJ homolog subfamily C member 2 Endoplasmic reticulum chaperone BiP Glycogen synthase kinase-3 beta Heat shock 70 kDa protein 1-like Heat shock 70 kDa protein 13 Heat shock 70 kDa protein 14 Heat shock 70 kDa protein 1A Heat shock 70 kDa protein 1B Heat shock 70 kDa protein 4 Heat shock cognate 71 kDa protein Heat shock protein 105 kDa Heat shock protein family A (Hsp70) member 12A Heat shock protein family A (Hsp70) member 12B Heat shock transcription factor 1 Heat shock-related 70 kDa protein 2 Hsc70-interacting protein LOC683983 protein MAPK activated protein kinase 2 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 NAD-dependent protein deacetylase sirtuin-1 Nuclear envelope pore membrane protein POM 121 Nuclear pore complex protein Nup107 Nuclear pore complex protein Nup153 Nuclear pore complex protein Nup155 Nuclear pore complex protein Nup50 Nuclear pore complex protein Nup54 Nuclear pore complex protein Nup85 Nuclear pore complex protein Nup88 Nuclear pore complex protein Nup93 Nuclear pore complex protein Nup98-Nup96 Nuclear pore glycoprotein p62 Nuclear pore membrane glycoprotein 210 Nucleoporin 133 Nucleoporin 160 Nucleoporin 205 Nucleoporin 214 Nucleoporin 37 Nucleoporin NDC1 Nucleoporin NUP188 Nucleoporin NUP35 Nucleoporin NUP42 Nucleoporin p58/p45 Nucleoprotein TPR Protein Hikeshi Protein SEC13 homolog RAN binding protein 2 Replication protein A 32 kDa subunit Replication protein A subunit Replication protein A3 Stress-70 protein, mitochondrial mRNA export factor	A0A0G2JZ79 A0A0G2K3M4 A0A0U1RRW3 A0A8I5YC36 A0A8I5YCH6 A0A8I5ZJ67 A0A8I6A691 A0A8I6AP78 B0BN74 B0BNB5 B0K019 D3Z8B2 D3ZBL6 D3ZHV0 D3ZUU5 D3ZVM5 D4A845 D4ACK1 F1LRC6 F1MA98 F1MAF1 O08587 O08658 O35162 O88600 P06761 P0DMW0 P0DMW1 P11654 P14659 P17955 P18266 P21708 P37199 P48721 P49791 P49793 P50503 P52590 P52591 P55063 P62260 P63018 P63086 P70581 P70582 Q3SWS8 Q4QQS8 Q5M808 Q5QJC9 Q5XFW8 Q63528 Q66HA8 Q66HC5 Q68FY1 Q6AXN4 Q6AYB4 Q6AYU3 Q7TP21 Q7TQ20 Q80ZF4	Aaas Bag1 Bag2 Bag4 Bag5 Dnajb1 Dnajb6 Dnajc2 Erk1 Erk2 Fam10a1 Gp210 Grp75 Grp78 Gsk3b Hikeshi Hip Hsc70 Hsc73 Hsf1 Hsp105 Hsp110 Hsp70-1 Hsp70-2 Hsp70-3 Hspa1 Hspa12a Hspa12b Hspa13 Hspa14 Hspa1a Hspa1b Hspa1l Hspa2 Hspa4 Hspa5 Hspa8 Hspa9 Hspa9a Hsph1 Hsph2 Hst70 Irp94 LOC683983 Mapk Mapk1 Mapk3 Mapkapk2 Mida1 Mrnp41 Ndc1 Npap60 Nup107 Nup121 Nup133 Nup153 Nup155 Nup160 Nup188 Nup205 Nup210 Nup214 Nup35 Nup37 Nup42 Nup43 Nup50 Nup53 Nup54 Nup58 Nup62 Nup84 Nup85 Nup88 Nup93 Nup98 Nupl1 Nupl2 Pcnt1 Pom121 Pom210 Prkm1 Prkm3 Rae1 Ranbp2 Rpa1 Rpa2 Rpa3 Rps19bp1 Sec13 Sec13l1 Sirt1 St13 Stch Tmem48 Tpr Ywhae Zrf1	Rattus norvegicus (Norway rat)
Ovarian tumor domain proteases	Adenomatous polyposis coli protein Cellular tumor antigen p53 Cyclin-dependent kinase 1 Deubiquitinating protein VCPIP1 Estrogen receptor NF-kappa-B essential modulator NF-kappa-B essential modulator Nucleotide-binding oligomerization domain containing 1 Nucleotide-binding oligomerization domain containing 2 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN Polyubiquitin-B Polyubiquitin-C Receptor interacting serine/threonine kinase 1 Receptor-interacting serine/threonine-protein kinase 2 Ring finger protein 128 TNF receptor-associated factor 6 TNF receptor-associated factor TNFAIP3 interacting protein 1 TNFAIP3 interacting protein 2 Transforming protein RhoA Transitional endoplasmic reticulum ATPase Ubiquitin B-like Ubiquitin thioesterase OTU1 Ubiquitin thioesterase OTUB1 Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-ribosomal protein eS31 fusion protein ubiquitinyl hydrolase 1 ubiquitinyl hydrolase 1 ubiquitinyl hydrolase 1 ubiquitinyl hydrolase 1 ubiquitinyl hydrolase 1 ubiquitinyl hydrolase 1	A0A0G2K4Z7 A0A0G2K5N0 A0A0G2K7X2 A0A8I6A5Y3 A0A8I6AH74 A0A8I6AL23 A0A8I6AU71 B2RYG6 B2RZ84 B5DF45 D3ZAR8 D3ZDK2 D3ZHV1 D3ZYL0 D4A3I0 D4A7M3 D4ABZ4 D4ADT7 G3V783 G3V7R6 P06211 P0CG51 P10361 P39951 P46462 P61589 P62982 P70478 Q32Q05 Q63429 Q6TMG5 Q8CF97	Apc Arha Arha2 Cdc2 Cdc2a Cdk1 Cdkn1 Esr Esr1 Estr Hshin7 Ikbkg LOC100360606 LOC100360645 Nemo Nod1 Nod2 Nr3a1 Otub1 Otub2 Otud3 Otud7a Otud7b P53 Pten Rhoa Ripk1 Ripk2 Rnf128 Rps27a Tnfaip3 Tnip1 Tnip2 Tp53 Traf3 Traf6 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1 Ube2d1 Vcip135 Vcp Vcpip1 Yod1 Zranb1	Rattus norvegicus (Norway rat)
Formation of the ternary complex, and subsequently, the 43S complex	40S ribosomal protein S12 40S ribosomal protein S26 40S ribosomal protein S7 Eukaryotic translation initiation factor 1A Eukaryotic translation initiation factor 2 subunit 1 Eukaryotic translation initiation factor 2 subunit 2 Eukaryotic translation initiation factor 2 subunit 3, X-linked Eukaryotic translation initiation factor 3 subunit A Eukaryotic translation initiation factor 3 subunit B Eukaryotic translation initiation factor 3 subunit C Eukaryotic translation initiation factor 3 subunit D Eukaryotic translation initiation factor 3 subunit E Eukaryotic translation initiation factor 3 subunit F Eukaryotic translation initiation factor 3 subunit G Eukaryotic translation initiation factor 3 subunit H Eukaryotic translation initiation factor 3 subunit I Eukaryotic translation initiation factor 3 subunit J Eukaryotic translation initiation factor 3 subunit K Eukaryotic translation initiation factor 3 subunit L Eukaryotic translation initiation factor 3 subunit M Small ribosomal subunit protein eS10 Small ribosomal subunit protein eS17 Small ribosomal subunit protein eS19 Small ribosomal subunit protein eS1 Small ribosomal subunit protein eS21 Small ribosomal subunit protein eS24 Small ribosomal subunit protein eS25 Small ribosomal subunit protein eS26 Small ribosomal subunit protein eS27-like Small ribosomal subunit protein eS27 Small ribosomal subunit protein eS28 Small ribosomal subunit protein eS4 Small ribosomal subunit protein eS4 Small ribosomal subunit protein eS6 Small ribosomal subunit protein eS7 Small ribosomal subunit protein eS8 Small ribosomal subunit protein uS10 Small ribosomal subunit protein uS11 Small ribosomal subunit protein uS12 Small ribosomal subunit protein uS13 Small ribosomal subunit protein uS14 Small ribosomal subunit protein uS15 Small ribosomal subunit protein uS17 Small ribosomal subunit protein uS19 Small ribosomal subunit protein uS2 Small ribosomal subunit protein uS3 Small ribosomal subunit protein uS4 Small ribosomal subunit protein uS5 Small ribosomal subunit protein uS5 Small ribosomal subunit protein uS7 Small ribosomal subunit protein uS8 Small ribosomal subunit protein uS9 Ubiquitin-like protein FUBI Ubiquitin-ribosomal protein eS31 fusion protein	A0A8I5ZLD0 A0A8I5ZX29 A0A8I6AIB7 A0A8I6G5P0 A0A8I6GEL5 A0JPM9 B0BNA7 B5DFC8 D3Z8D7 D3ZAZ0 D3ZT78 D3ZX01 D4AC36 P04644 P05765 P13471 P17074 P24050 P24051 P27952 P29314 P38983 P49242 P60868 P62083 P62243 P62246 P62250 P62268 P62271 P62275 P62278 P62282 P62703 P62755 P62845 P62850 P62853 P62856 P62859 P62909 P62982 P63326 P68101 P81795 Q05474 Q1JU68 Q4G061 Q5RK09 Q641X8 Q6AYK8 Q6P9U8 Q6VV72 Q71TY3	AABR07029195.1 EIF3EIP EIF3F EIF3K EIF3L EIF3M EIF3S12 EIF3S5 EIF3S6IP Eif1a Eif2a Eif2g Eif2s1 Eif2s2 Eif2s3 Eif2s3x Eif3a Eif3b Eif3c Eif3d Eif3e Eif3f Eif3g Eif3h Eif3i Eif3j Eif3k Eif3l Eif3m Eif3s1 Eif3s10 Eif3s2 Eif3s3 Eif3s4 Eif3s6 Eif3s7 Eif3s8 Eif3s9 Fau Fte-1 Fte1 Int6 LOC100361854 LOC100361933 Lamr1 Rig Rps10 Rps11 Rps12l8 Rps13 Rps14 Rps15 Rps15a Rps16 Rps17 Rps18 Rps19 Rps2 Rps20 Rps21 Rps23 Rps24 Rps25 Rps26 Rps26-ps13 Rps26l2 Rps26l4 Rps26l6 Rps27 Rps27a Rps27l Rps28 Rps29 Rps3 Rps3a Rps4 Rps4x Rps4y2 Rps5 Rps6 Rps7 Rps7-ps23 Rps8 Rps9 Rpsa S27-1 Uba80 Ubcep1	Rattus norvegicus (Norway rat)
SUMOylation of immune response proteins	E3 SUMO-protein ligase PIAS3 Inhibitor of nuclear factor kappa B kinase subunit epsilon NF-kappa-B essential modulator NF-kappa-B essential modulator NF-kappa-B inhibitor alpha Nuclear factor kappa B subunit 2 Protein inhibitor of activated STAT, 4 RELA proto-oncogene, NF-kB subunit RING-type E3 ubiquitin transferase SUMO-conjugating enzyme UBC9 Small ubiquitin-related modifier 1 Small ubiquitin-related modifier 3	A0A8I5ZMV7 A0A8I6AH74 A0A8I6ANV8 A0A8I6G6F3 B5DFF9 D4A5E7 O70260 P63281 Q5I0H3 Q5XIF4 Q63746 Q6TMG5	Ikba Ikbke Ikbkg Nemo Nfkb2 Nfkbia Pias3 Pias4 Rela Sumo1 Sumo3 Topors Ubce9 Ube2i	Rattus norvegicus (Norway rat)
Intracellular metabolism of fatty acids regulates insulin secretion	Fatty acid CoA ligase Acsl3 Long-chain-fatty-acid--CoA ligase 4 Platelet glycoprotein 4	O35547 Q07969 Q63151	Acs3 Acs4 Acsl3 Acsl4 Cd36 Facl3 Facl4 Fat	Rattus norvegicus (Norway rat)
Growth hormone receptor signaling	Growth hormone receptor Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Prolactin receptor Prolactin SH2B adapter protein 1 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Somatotropin Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Lyn Tyrosine-protein phosphatase non-receptor type 1	P01237 P01244 P05710 P16310 P20417 P21708 P52632 P63086 Q07014 Q62689 Q62771 Q62985	Erk1 Erk2 Gh Gh1 Ghr Jak2 Lyn Mapk Mapk1 Mapk3 Mgf Prkm1 Prkm3 Prl Prlr Ptpn1 Sh2-b Sh2b1 Sh2bpsm1 Stat5a Stat5b	Rattus norvegicus (Norway rat)
Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE)	Cytochrome P450 1A1 Cytochrome P450 1A2 Cytochrome P450 1B1 Cytochrome P450 2C26-like Cytochrome P450 2U1 Cytochrome P450 4A12 Cytochrome P450 4F4	A0A8I6AFV7 P00185 P04799 P24464 P51869 Q4V8D1 Q64678	Cyp1a-1 Cyp1a-2 Cyp1a1 Cyp1a2 Cyp1b1 Cyp2c66 Cyp2u1 Cyp4a-8 Cyp4a12 Cyp4a8 Cyp4f4 LOC100912265	Rattus norvegicus (Norway rat)
Sealing of the nuclear envelope (NE) by ESCRT-III	Charged multivesicular body protein 2B Charged multivesicular body protein 2a Charged multivesicular body protein 3 Charged multivesicular body protein 4B Charged multivesicular body protein 4c Charged multivesicular body protein 6 Charged multivesicular body protein 7 Coiled-coil and C2 domain-containing protein 1B IST1 homolog Spastin Tubulin alpha chain Tubulin alpha-1A chain Tubulin alpha-1B chain Tubulin alpha-1C chain Tubulin alpha-3 chain Tubulin alpha-4A chain Tubulin alpha-8 chain Tubulin beta chain Tubulin beta-2A chain Tubulin beta-2B chain Tubulin beta-3 chain Tubulin beta-4B chain Vacuolar protein sorting-associated protein 4A	A0A8I5ZP83 A0A8I5ZY10 A0A8I6AB52 A0A8I6AQ75 B2RYN7 D4A7H9 F1LUM5 M0R8B6 P68370 P85108 Q3KRE8 Q4QRB4 Q568Z6 Q569C1 Q5FVK6 Q5XIF6 Q68FR8 Q6AY56 Q6AYZ1 Q6P9T8 Q6P9V9 Q793F9 Q8CGS4	Cc2d1b Chmp2a Chmp2b Chmp3 Chmp4b Chmp4c Chmp6 Chmp7 Ist1 LOC679312 Spast Spg4 Tuba1 Tuba1a Tuba1b Tuba1c Tuba2 Tuba3 Tuba3a Tuba3b Tuba4 Tuba4a Tuba6 Tuba8 Tubal3 Tubb1 Tubb2a Tubb2b Tubb2c Tubb3 Tubb4b Vps24 Vps4a vps4-A	Rattus norvegicus (Norway rat)
Calcitonin-like ligand receptors	Calcitonin gene-related peptide 2 Calcitonin gene-related peptide type 1 receptor Calcitonin receptor Calcitonin Islet amyloid polypeptide Pro-adrenomedullin Protein ADM2 Receptor activity-modifying protein 1 Receptor activity-modifying protein 2 Receptor activity-modifying protein 3	P01257 P10093 P12969 P32214 P43145 P61312 Q63118 Q9JHJ1 Q9JJ73 Q9JJ74	Adm Adm2 Am2 Calc Calca Calcb Calcr Calcrl Cgrpr Iapp Ramp1 Ramp2 Ramp3	Rattus norvegicus (Norway rat)
Signaling by BMP	Activin receptor type-2A Activin receptor type-2B Anti-Muellerian hormone type-2 receptor Bone morphogenetic protein 10 Bone morphogenetic protein 2 Bone morphogenetic protein receptor type-1A Chordin-like protein 1 E3 ubiquitin-protein ligase E3 ubiquitin-protein ligase Follistatin-related protein 1 Gremlin Growth differentiation factor 2 Inhibin alpha chain Inhibin beta A chain Mothers against decapentaplegic homolog 1 Mothers against decapentaplegic homolog 4 Mothers against decapentaplegic homolog 5 Mothers against decapentaplegic homolog 7 Mothers against decapentaplegic homolog 9 Mothers against decapentaplegic homolog Muellerian-inhibiting factor Serine/threonine-protein kinase receptor R3 Serine/threonine-protein kinase receptor Ski oncogene Transforming growth factor beta receptor type 3 Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 D3 Zinc finger FYVE-type containing 16 receptor protein serine/threonine kinase	A0A0G2K612 A0A0G2K628 A0A8I5Y0P5 A0A8I5ZXN2 A0A8I6AM39 D3ZAQ2 D3ZDK2 D3ZXD0 D4ADF6 M0RB87 O54835 O70437 O88406 P17490 P18331 P26342 P38444 P38445 P49000 P49001 P61078 P80203 P97588 Q4AEG6 Q62632 Q62893 Q76LD0 Q78EA7 Q9R1V3	Actrii Actriib Acvr2 Acvr2a Acvr2b Acvrl1 Acvrlk1 Amh Amhr2 Bmp-2 Bmp10 Bmp2 Bmpr1a Bmpr1b Bmpr2 Chrdl1 Frp Fstl1 Gdf2 Grem2 Inha Inhba Kjr Mad1 Madh1 Madh4 Madh5 Madh7 Madh8 Madh9 Ng1 Ski Smad1 Smad4 Smad5 Smad6 Smad7 Smad8 Smad9 Smurf1 Smurf2 Tgfbr3 Ube2d1 Ube2d3 Zfyve16	Rattus norvegicus (Norway rat)
Negative regulation of FGFR3 signaling	E3 ubiquitin-protein ligase CBL Fibroblast growth factor 16 Fibroblast growth factor 17 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor 9 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Growth factor receptor-bound protein 2 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Polyubiquitin-B Polyubiquitin-C Tyrosine-protein phosphatase non-receptor type 11 Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein	A0A0G2K210 A0A8I6A5Y3 A0A8I6B5D5 A0A8I6G3R2 D4A244 F1LSQ8 O54769 O88182 P0CG51 P13109 P21708 P36364 P41499 P48807 P61149 P62982 P62994 P63076 P63086 Q63429 Q8VI82 Q9EST9	Ash Cbl Erk1 Erk2 Fgf-1 Fgf-2 Fgf-5 Fgf-9 Fgf1 Fgf16 Fgf17 Fgf18 Fgf2 Fgf20 Fgf23 Fgf4 Fgf5 Fgf7a Fgf8 Fgf9 Fgfa Fgfr3 Frs2 Grb2 LOC100360645 Mapk Mapk1 Mapk3 Prkm1 Prkm3 Ptpn11 Rps27a Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1	Rattus norvegicus (Norway rat)
HuR (ELAVL1) binds and stabilizes mRNA	Acidic leucine-rich nuclear phosphoprotein 32 family member A ELAV-like protein 1 Exportin-1 Nucleoporin 214 Protein SET Protein kinase C alpha type Protein kinase C delta type TNF superfamily member 13	A0A8J8XC20 B5DF91 D4ACK1 P05696 P09215 P49911 Q63945 Q80U96	Anp32a Crm1 Elavl1 Hur Lanp Nup214 Pkca Pkcd Prkca Prkcd Set Tnfsf13 Xpo1	Rattus norvegicus (Norway rat)
Formation of the cornified envelope	Caspase 14 Chymotrypsin-like elastase family member 2A Corneodesmosin Desmocollin 1 Desmocollin 2 Desmocollin 3 Desmoglein 1 Desmoglein 2 Desmoglein 3 Desmoglein-4 Desmoplakin Envoplakin Junction plakoglobin Kallikrein k Kallikrein l Kallikrein m Kallikrein related-peptidase 5 Kallikrein-8 Kazrin Lipase Lipase Lipase P53 apoptosis effector related to PMP22 Periplakin Plakophilin 1 Plakophilin 3 Plakophilin 4 Plakophilin-2 Protein-glutamine gamma-glutamyltransferase K Repetin Serine peptidase inhibitor, Kazal type 5 Serine protease inhibitor Kazal-type 6 Small proline-rich protein 3 Stefin A2-like 3	A0A0G2K230 A0A0G2K430 A0A0G2KA90 A0A8I5ZKH8 A0A8I6A880 A0A8I6AG90 A0A8I6GLK6 B2GVC0 D3ZD22 D3ZET2 D3ZHQ6 D3ZJ50 D3ZJ70 D3ZJR7 D3ZL74 D3ZM39 D3ZRA7 D3ZRF0 D3ZY51 D3ZZ65 D4A5T8 D4A9L7 D4AA61 F1LMV6 F1M091 F1M7L9 G3V765 O88780 P00774 P23606 Q5FWS6 Q6IE47 Q6P0K8 Q6W3B0	AABR07044375.1 Bsp1 Casp14 Cdsn Cela2a Dsc1 Dsc2 Dsc3 Dsg1 Dsg2 Dsg3 Dsg4 Dsp Ela2 Ela2a Evpl Jup Kaz Kazn Klk12 Klk13 Klk14 Klk5 Klk8 Klnk Klnl Klnm Lipk Lipm Lipn Nrpn Perp Pg Pkp1 Pkp2 Pkp3 Pkp4 Ppl Prss19 Rptn Spink5 Spink5l1 Spink6 Sprr3 Stfa2l3 Tgm1	Rattus norvegicus (Norway rat)
Signaling by Retinoic Acid	Ac1164 Carnitine O-palmitoyltransferase 1, liver isoform Carnitine O-palmitoyltransferase 1, muscle isoform Cellular retinoic acid-binding protein 2 Dihydrolipoyl dehydrogenase, mitochondrial Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial Fatty acid-binding protein 5 Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial Pyruvate dehydrogenase E1 component subunit alpha Pyruvate dehydrogenase E1 component subunit beta, mitochondrial Retinoic acid receptor RXR-alpha Retinoic acid receptor RXR-beta (Fragment) Retinoic acid receptor RXR-gamma Retinoic acid receptor beta Retinoic acid receptor, alpha Retinoic acid receptor, gamma [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial	A0A0G2JW78 A0A8I6A7Z0 D3ZWV0 D4A5G8 O54937 P08461 P26284 P32198 P49432 P49743 P51673 P55053 Q05343 Q06437 Q5BJR8 Q63065 Q63704 Q64536 Q6P6R2 Q7TQ85	Cpt-1 Cpt1 Cpt1a Cpt1b Crabp2 Dlat Dld Fabp5 LOC311254 Nr2b1 Nr2b2 Nr2b3 Pdh Pdha1 Pdha1l1 Pdha2 Pdhb Pdhx Pdk1 Pdk2 Pdk4 Rara Rarb Rarg Rcor-1 Rxra Rxrb Rxrg	Rattus norvegicus (Norway rat)
FGFR1c ligand binding and activation	Fibroblast growth factor 17 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor 9 Fibroblast growth factor receptor 1 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor PDZ domain-containing protein GIPC1 Transforming growth factor beta receptor type 3	A0A8I6B5D5 F1LSQ8 P13109 P26342 P36364 P48807 P61149 P63076 Q04589 Q8R5L5 Q8VI82 Q9EST9 Q9Z254	FGF6 Fgf-1 Fgf-2 Fgf-5 Fgf-9 Fgf1 Fgf17 Fgf2 Fgf20 Fgf23 Fgf4 Fgf5 Fgf6 Fgf7a Fgf7b Fgf8 Fgf9 Fgfa Fgfr1 Flg Gipc Gipc1 Rgs19ip1 Tgfbr3	Rattus norvegicus (Norway rat)
Formation of the beta-catenin:TCF transactivating complex	BCL9 like BCL9, transcription coactivator Catenin beta-1 Histone acetyltransferase KAT5 Histone deacetylase 1 Histone lysine acetyltransferase CREBBP Lymphoid enhancer-binding factor 1 Parafibromin Pygopus family PHD finger 1 Pygopus family PHD finger 2 RNA polymerase-associated protein LEO1 RuvB-like 1 TLE family member 1, transcriptional corepressor TLE family member 2, transcriptional corepressor Telomerase reverse transcriptase Transcription activator BRG1 Transcription factor 7 like 1 Transcription factor 7 like 2 Transcription factor 7 Transducin-like enhancer protein 3 Transducin-like enhancer protein 4 Transformation/transcription domain-associated protein histone acetyltransferase	A0A0G2K109 A0A8I5ZLY3 A0A8I5ZT78 A0A8I6A6Y0 A0A8I6A9A2 A0A8I6AA06 A0A8I6AT29 A0A8I6G641 A0A8I6GB32 A0A8I6GLC1 B5DFG8 P60123 Q07141 Q4QQW4 Q4V8C8 Q641X2 Q673L6 Q6JHU9 Q8K1P7 Q99MK2 Q9JIT3 Q9QXN1 Q9WU82	Baf190a Bcl9 Bcl9l Brg1 Catnb Cbp Cdc73 Crebbp Ctnnb1 Ep300 Esp2 Esp3 Grg4 Hdac1 Hrpt2 Htatip Kat5 Lef1 Leo1 Pygo1 Pygo2 Ruvbl1 Smarca4 Snf2b Snf2l4 Tcf7 Tcf7l1 Tcf7l2 Tert Tip49 Tip49a Tip60 Tip60b Tle1 Tle2 Tle3 Tle4 Trrap	Rattus norvegicus (Norway rat)
Regulated proteolysis of p75NTR	Disintegrin and metalloproteinase domain-containing protein 17 Gamma-secretase subunit APH-1 Gamma-secretase subunit PEN-2 Nicastrin Presenilin-1 Presenilin-2 Tumor necrosis factor receptor superfamily member 16	F7EYZ3 O88777 P07174 P97887 Q6QI68 Q8CGU6 Q9Z1K9	Adam17 Aph1a Ncstn Ngfr Ps2 Psen1 Psen2 Psenen Psnl1 Psnl2 Tace Tnfrsf16	Rattus norvegicus (Norway rat)
Regulation of TP53 Activity through Phosphorylation	5'-AMP-activated protein kinase catalytic subunit alpha-1 5'-AMP-activated protein kinase subunit beta-1 5'-AMP-activated protein kinase subunit beta-2 5'-AMP-activated protein kinase subunit gamma-1 ATR interacting protein Aurora kinase A Aurora kinase B BRCA1 interacting helicase 1 BRCA1-associated RING domain protein 1 Breast cancer type 1 susceptibility protein homolog Casein kinase II subunit alpha Casein kinase II subunit alpha Casein kinase II subunit beta Cell cycle checkpoint control protein RAD9B Cell cycle checkpoint control protein Cellular tumor antigen p53 Checkpoint protein Cyclin-A1 Cyclin-A2 Cyclin-dependent kinase 2 Cyclin-dependent kinase 5 activator 1 Cyclin-dependent kinase 5 DNA 3'-5' helicase DNA 3'-5' helicase DNA endonuclease RBBP8 DNA repair protein RAD50 DNA replication ATP-dependent helicase/nuclease DNA2 DNA topoisomerase II binding protein 1 DNA topoisomerase Double-strand break repair protein MRE11 E3 ubiquitin-protein ligase Mdm2 Exonuclease 1 FACT complex subunit SSRP1 FACT complex subunit Histone acetyltransferase KAT5 Homeodomain-interacting protein kinase 1 MAPK activated protein kinase 5 Mapk11 protein Mitogen-activated protein kinase 14 NOC2-like nucleolar associated transcriptional repressor Nibrin Polyubiquitin-B Polyubiquitin-C Protein Mdm4 Protein kinase AMP-activated non-catalytic subunit gamma 2 Protein kinase AMP-activated non-catalytic subunit gamma 3 RAD1 checkpoint DNA exonuclease RAD17 checkpoint clamp loader component RAD9, HUS1, RAD1-interacting nuclear orphan protein 1 RecQ mediated genome instability 2 RecQ-mediated genome instability protein 1 Replication factor C subunit 2 Replication factor C subunit 3 Replication factor C subunit 4 Replication factor C subunit 5 Replication protein A 32 kDa subunit Replication protein A subunit Replication protein A3 Serine-protein kinase ATM Serine/threonine-protein kinase ATR Serine/threonine-protein kinase Chk1 Serine/threonine-protein kinase PLK3 Serine/threonine-protein kinase STK11 TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, pseudogene 1 TATA-box binding protein associated factor 13 TATA-box binding protein associated factor 15 TATA-box binding protein associated factor 4 TATA-box binding protein associated factor 4b TATA-box binding protein associated factor 5 TATA-box-binding protein TPX2, microtubule nucleation factor Transcription initiation factor TFIID subunit 11 Transcription initiation factor TFIID subunit 12 Transcription initiation factor TFIID subunit 2 Transcription initiation factor TFIID subunit 6 Transcription initiation factor TFIID subunit 7 Transcription initiation factor TFIID subunit 9 Transcription initiation factor TFIID subunit 9B Transcription initiation factor TFIID subunit Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein dual-specificity kinase non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase	A0A0G2JVY9 A0A0G2K475 A0A0G2K4W8 A0A0G2K849 A0A140UHX4 A0A8I5ZJ57 A0A8I6A014 A0A8I6A5Y3 A0A8I6A7M0 A0A8I6A9T0 A0A8I6ABQ9 A0A8I6G5V3 A0A8I6GFZ6 A4L9P5 B0BN78 B1WC58 B2RYG5 B2RYQ7 B4F778 B5DF29 D3Z822 D3ZA78 D3ZC52 D3ZCD7 D3ZG52 D3ZH66 D3ZHX4 D3ZL21 D3ZNA8 D3ZQN8 D3ZQW1 D3ZXM2 D4A3U7 D4A4M3 D4A6J4 D4A7E4 D4A845 D4ACL8 D4AE59 E9PTF3 E9PTL1 F1LN87 F1LNY6 F1LT11 F1LTH9 F1LV83 F1LYY7 F7FH41 O54952 O55099 P0CG51 P10361 P19139 P54645 P59241 P61810 P62982 P67874 P70618 P80385 P80386 Q03114 Q04931 Q499V3 Q5BKE0 Q5M830 Q5U1X0 Q5XIN1 Q62880 Q63429 Q63528 Q63699 Q63801 Q641W4 Q6AY13 Q6AY26 Q7TP21 Q91ZN7 Q99MK2 Q9JIL8 Q9JIL9 Q9JIM0 Q9QZH2 Q9QZH4 Q9R011	Aik Aik2 Aim1 Airk1 Airk2 Ampk1 Ark1 Ark2 Atm Atr Atrip Aura Aurka Aurkb Ayk1 Bard1 Blm Brca1 Brip1 Btak Ccna1 Ccna2 Cdk2 Cdk5 Cdk5r Cdk5r1 Cdkn2 Cdkn5 Chek1 Chk1 Ciidbp Ck2n Cnk Csbp1 Csbp2 Csnk2a1 Csnk2a2 Csnk2b Ctip Dn7 Dna2 Dyrk2 Exo1 Fnk Hipk1 Htatip Hus1 Iak1 Kat5 LOC100360645 LOC685619 Lkb1 Mapk11 Mapk14 Mapkapk5 Mdm2 Mdm4 Mdmx Mre11 Mre11a Nbn Nbs1 Noc2l Nuak1 P53 PSSALRE Plk3 Prkaa1 Prkab1 Prkab2 Prkag1 Prkag2 Prkag3 RGD1564788 Rad1 Rad17 Rad50 Rad9a Rad9b Rbbp8 Rfc2 Rfc3 Rfc4 Rfc5 Rhno1 Rmi1 Rmi2 Rpa1 Rpa2 Rpa3 Rps27a Ssrp1 Stk1 Stk11 Stk12 Stk15 Stk5 Stk6 Supt16h Taf1 Taf11 Taf12 Taf13 Taf15 Taf2 Taf2e Taf2g Taf4 Taf4b Taf5 Taf6 Taf7 Taf7l-ps1 Taf9 Taf9b Taf9l Tafii31 Tbp Tip60 Tip60b Top3a Topbp1 Tp53 Tp53rk Tp53rka Tp53rkb Tpx2 Trp53rka Trp53rkb Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1 Wrn	Rattus norvegicus (Norway rat)

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