neurodegenerative disease

Summary
Synonym
  • degenerative disease
Definition
A central nervous system disease that results in the progressive deterioration of function or structure of neurons.
Super Class
central nervous system disease
Disease Ontology
DOID:1289
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 81 - 90 of 106 in total
Gene ID Gene Symbol Description Source
26524 LATS2 large tumor suppressor kinase 2
29978 UBQLN2 ubiquilin 2
29979 UBQLN1 ubiquilin 1
51087 YBX2 Y-box binding protein 2
51422 PRKAG2 protein kinase AMP-activated non-catalytic subunit gamma 2
53335 BCL11A BCL11 transcription factor A
53632 PRKAG3 protein kinase AMP-activated non-catalytic subunit gamma 3
54893 MTMR10 myotubularin related protein 10
55666 NPLOC4 NPL4 homolog, ubiquitin recognition factor
56893 UBQLN4 ubiquilin 4
Displaying entries 41 - 50 of 73 in total
Gene ID Gene Symbol Description Source
30960 Vapa vesicle-associated membrane protein, associated protein A
50767 Pnpla6 patatin-like phospholipase domain containing 6
53357 Pla2g6 phospholipase A2, group VI
53623 Gria3 glutamate receptor, ionotropic, AMPA3 (alpha 3)
54609 Ubqln2 ubiquilin 2
55963 Slc1a4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
56434 Tspan3 tetraspanin 3
67095 Trak1 trafficking protein, kinesin binding 1
69597 Afg3l2 AFG3-like AAA ATPase 2
70417 Megf10 multiple EGF-like-domains 10
Displaying entries 21 - 30 of 33 in total
Gene ID Gene Symbol Description Source
84487 Slc17a6 solute carrier family 17 member 6
94198 Psmb1 proteasome 20S subunit beta 1
157074 Sdha succinate dehydrogenase complex flavoprotein subunit A
171086 Trak2 trafficking kinesin protein 2
266767 Slc17a8 solute carrier family 17 member 8
287545 Sarm1 sterile alpha and TIR motif containing 1
296851 Pon2 paraoxonase 2
298521 Grik3 glutamate ionotropic receptor kainate type subunit 3
300733 Tspan3 tetraspanin 3
312086 Pon3 paraoxonase 3
Displaying entries 1 - 10 of 15 in total
Gene ID Gene Symbol Description Source
31002 Appl beta amyloid protein precursor-like
31902 Gga Golgi-localized, gamma-adaptin ear containing, ARF binding protein
33627 ft fat
33658 FIG4 FIG4 phosphoinositide 5-phosphatase
35784 Nup50 Nucleoporin 50kD
35851 ptc patched
36484 AttC Attacin-C
36635 Dro Drosocin
38218 drpr draper
38419 Drs Drosomycin
Displaying entries 1 - 10 of 19 in total
Gene ID Gene Symbol Description Source
192309 tpi1a triosephosphate isomerase 1a
403143 sarm1 sterile alpha and TIR motif containing 1
406411 rhoaa ras homolog gene family, member Aa
406659 rhoac ras homolog gene family, member Ac
407667 asic4b acid-sensing (proton-gated) ion channel family member 4b
407668 asic4a acid-sensing (proton-gated) ion channel family member 4a
407669 asic2 acid-sensing (proton-gated) ion channel 2
407670 asic1c acid-sensing (proton-gated) ion channel 1c
407672 asic1b acid-sensing (proton-gated) ion channel 1b
436718 rhocb ras homolog family member Cb
Displaying all 3 entries
Gene ID Gene Symbol Description Source Organism
448598 pon2 paraoxonase 2 Xenopus tropicalis (tropical clawed frog)
780064 slc17a7 solute carrier family 17 (vesicular glutamate transporter), member 7 Xenopus tropicalis (tropical clawed frog)
100038162 tpi1 triosephosphate isomerase 1 Xenopus tropicalis (tropical clawed frog)
Displaying entries 1 - 10 of 15 in total
Gene ID Gene Symbol Description Source
173064 ced-1 Cell death abnormality protein 1
173631 ptc-3 Protein patched homolog 3
174274 ptc-1 Protein patched homolog 1;SSD domain-containing protein
175502 tir-1 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase;NAD(+) hydrolase tir-1;Sterile alpha and TIR motif-containing protein 1
176204 glr-1 Glutamate receptor 1
176291 eat-4 Major facilitator superfamily (MFS) profile domain-containing protein;putative vesicular glutamate transporter eat-4
176441 vglu-2 Major facilitator superfamily (MFS) profile domain-containing protein
176442 vglu-3 putative vesicular glutamate transporter vglu-3
177882 glt-3 Putative sodium-dependent excitatory amino acid transporter glt-3
180783 apl-1 Amyloid-beta-like protein
Displaying all 10 entries
Gene ID Gene Symbol Description Source
851013 ACO1 aconitate hydratase ACO1
851620 TPI1 triose-phosphate isomerase TPI1
853173 MTM1 Mtm1p
853770 BUD2 GTPase-activating protein BUD2
853792 OSI1 Osi1p
854943 NTE1 lysophospholipase
855392 FIG4 phosphatidylinositol-3,5-bisphosphate 5-phosphatase
855897 HRR25 serine/threonine protein kinase HRR25
856294 RHO1 Rho family GTPase RHO1
856422 RPN1 proteasome regulatory particle base subunit RPN1

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