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Standards Ontologies Notations
Parkinson's disease

Summary
Synonym
  • Parkinson disease
  • paralysis agitans
Definition
A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.
Super Class
synucleinopathy
External Links
Disease Ontology
DOID:14330
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
ORDO
OMIM
GARD
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 41 - 50 of 180 in total
Gene ID Gene Symbol Description Source
2053 EPHX2 epoxide hydrolase 2
2056 EPO erythropoietin
2064 ERBB2 erb-b2 receptor tyrosine kinase 2
2232 FDXR ferredoxin reductase
2308 FOXO1 forkhead box O1
2309 FOXO3 forkhead box O3
2580 GAK cyclin G associated kinase
2629 GBA1 glucosylceramidase beta 1
2668 GDNF glial cell derived neurotrophic factor
2745 GLRX glutaredoxin
Displaying entries 1 - 10 of 146 in total
Gene ID Gene Symbol Description Source
11350 Abl1 c-abl oncogene 1, non-receptor tyrosine kinase
11423 Ache acetylcholinesterase
11529 Adh7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
11607 Agtr1a angiotensin II receptor, type 1a
11608 Agtr1b angiotensin II receptor, type 1b
11651 Akt1 thymoma viral proto-oncogene 1
11652 Akt2 thymoma viral proto-oncogene 2
11747 Anxa5 annexin A5
12064 Bdnf brain derived neurotrophic factor
12317 Calr calreticulin
Displaying entries 71 - 80 of 82 in total
Gene ID Gene Symbol Description Source
246097 Fas Fas cell surface death receptor
266606 Tor1a torsin family 1, member A
266767 Slc17a8 solute carrier family 17 member 8
292804 Gpi glucose-6-phosphate isomerase
297795 Npbwr1 neuropeptides B and W receptor 1
300733 Tspan3 tetraspanin 3
304884 Tor3a torsin family 3, member A
309465 Gsto2 glutathione S-transferase omega 2
361466 Tppp tubulin polymerization promoting protein
362112 Tor2a torsin family 2, member A
Displaying entries 1 - 10 of 25 in total
Gene ID Gene Symbol Description Source
31248 sgg shaggy
31399 Torsin torsin
31718 Tbh Tyramine beta hydroxylase
31806 Ogg1 8-oxoguanine DNA glycosylase
33007 Dop2R Dopamine 2-like receptor
33461 Pgk Phosphoglycerate kinase
35851 ptc patched
35886 Pgi Phosphoglucose isomerase
36232 Sod3 Superoxide dismutase 3
37191 5-HT1B 5-hydroxytryptamine (serotonin) receptor 1B
Displaying all 9 entries
Gene ID Gene Symbol Description Source
114549 ache acetylcholinesterase (Yt blood group)
436629 nus1 NUS1 dehydrodolichyl diphosphate synthase subunit
437021 tspan36 tetraspanin 36
494492 slc17a6a solute carrier family 17 member 6a
560788 parp1 poly (ADP-ribose) polymerase 1
563467 slc17a8 solute carrier family 17 member 8
768121 foxo1a forkhead box O1 a
100004455 epoa erythropoietin a
100149756 slc17a6b solute carrier family 17 member 6b
Displaying all 7 entries
Gene ID Gene Symbol Description Source Organism
397750 hmgcr.L 3-hydroxy-3-methylglutaryl-CoA reductase L homeolog Xenopus laevis (African clawed frog)
398022 igf1r.S insulin like growth factor 1 receptor S homeolog Xenopus laevis (African clawed frog)
398763 agtr1.L angiotensin II receptor type 1 L homeolog Xenopus laevis (African clawed frog)
399170 akt1.S AKT serine/threonine kinase 1 S homeolog Xenopus laevis (African clawed frog)
779087 gdnf.L glial cell derived neurotrophic factor L homeolog Xenopus laevis (African clawed frog)
780064 slc17a7 solute carrier family 17 (vesicular glutamate transporter), member 7 Xenopus tropicalis (tropical clawed frog)
108705891 drd5.S dopamine receptor D5 S homeolog Xenopus laevis (African clawed frog)
Displaying entries 1 - 10 of 26 in total
Gene ID Gene Symbol Description Source
171965 pgk-1 putative phosphoglycerate kinase
172105 unc-38 Acetylcholine receptor subunit alpha-type unc-38
172150 unc-63 Acetylcholine receptor subunit alpha-type unc-63
173574 gba-1 Putative glucosylceramidase 1
174274 ptc-1 Protein patched homolog 1;SSD domain-containing protein
174462 let-23 Receptor tyrosine-protein kinase let-23;receptor protein-tyrosine kinase
175076 ace-3 Carboxylic ester hydrolase
175410 daf-2 Insulin-like receptor subunit beta;Protein kinase domain-containing protein;receptor protein-tyrosine kinase
175807 ida-1 Receptor-type tyrosine-protein phosphatase-like ida-1
176291 eat-4 Major facilitator superfamily (MFS) profile domain-containing protein;putative vesicular glutamate transporter eat-4
Displaying entries 1 - 10 of 19 in total
Gene ID Gene Symbol Description Source
850370 PGK1 phosphoglycerate kinase
850721 SMF3 putative divalent metal ion transporter SMF3
851013 ACO1 aconitate hydratase ACO1
851171 HMG2 hydroxymethylglutaryl-CoA reductase (NADPH) HMG2
852351 AKL1 serine/threonine protein kinase AKL1
852470 SMY2 Smy2p
852495 PGI1 glucose-6-phosphate isomerase
852806 HSF1 stress-responsive transcription factor HSF1
853071 TIF4631 translation initiation factor eIF4G
853300 YAK1 serine/threonine protein kinase YAK1
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 19, 2024