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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
multiple sclerosis
Summary
- Synonym
-
- Generalized multiple sclerosis
- insular sclerosis
- Definition
- A demyelinating disease that involves damage to the fatty myelin sheaths around the axons of the brain and spinal cord resulting in demyelination and scarring.
- Super Class
- autoimmune disease of central nervous system demyelinating disease
External Links
- Disease Ontology
- DOID:2377
- Mondo Disease Ontology
- MeSH
- UMLS
- NCI Thesaurus
- OMIM
- GARD
- MGI genotype (from TogoID)
- WikiPathways (from TogoID)
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 7099 | TLR4 | toll like receptor 4 | |
| 7124 | TNF | tumor necrosis factor | |
| 7132 | TNFRSF1A | TNF receptor superfamily member 1A | |
| 7941 | PLA2G7 | phospholipase A2 group VII | |
| 9331 | B4GALT6 | beta-1,4-galactosyltransferase 6 | |
| 9334 | B4GALT5 | beta-1,4-galactosyltransferase 5 | |
| 9370 | ADIPOQ | adiponectin, C1Q and collagen domain containing | |
| 9563 | H6PD | hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase | |
| 9749 | PHACTR2 | phosphatase and actin regulator 2 | |
| 10198 | MPHOSPH9 | M-phase phosphoprotein 9 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 11423 | Ache | acetylcholinesterase | |
| 11450 | Adipoq | adiponectin, C1Q and collagen domain containing | |
| 11595 | Acan | aggrecan | |
| 11596 | Ager | advanced glycosylation end product-specific receptor | |
| 12064 | Bdnf | brain derived neurotrophic factor | |
| 12287 | Cacna1b | calcium channel, voltage-dependent, N type, alpha 1B subunit | |
| 12477 | Ctla4 | cytotoxic T-lymphocyte-associated protein 4 | |
| 12484 | Cd24a | CD24a antigen | |
| 12487 | Cd28 | CD28 antigen | |
| 12524 | Cd86 | CD86 antigen |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 83613 | Nefl | neurofilament light chain | |
| 83817 | Ache | acetylcholinesterase | |
| 116553 | Il13 | interleukin 13 | |
| 117029 | Ccr5 | C-C motif chemokine receptor 5 | |
| 117033 | Mmp12 | matrix metallopeptidase 12 | |
| 246097 | Fas | Fas cell surface death receptor | |
| 287287 | Il4 | interleukin 4 | |
| 287561 | Ccl7 | C-C motif chemokine ligand 7 | |
| 289218 | Ndufs2 | NADH:ubiquinone oxidoreductase core subunit S2 | |
| 301252 | Hsp90ab1 | heat shock protein 90 alpha family class B member 1 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 32158 | cac | cacophony | |
| 36585 | beta4GalNAcTA | beta1,4-N-acetylgalactosaminyltransferase A | |
| 39443 | Ptp69D | Protein tyrosine phosphatase 69D | |
| 39984 | Grd | Glycine receptor | |
| 41625 | Ace | Acetylcholine esterase | |
| 41840 | Hsc70-4 | Heat shock protein 70 cognate 4 | |
| 42490 | Mvl | Malvolio | |
| 43222 | Tl | Toll | |
| 43275 | Ser | Serrate | |
| 43425 | beta4GalNAcTB | beta1,4-N-acetylgalactosaminyltransferase B |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 114549 | ache | acetylcholinesterase (Yt blood group) | |
| 140421 | jag1a | jagged canonical Notch ligand 1a | |
| 393912 | b4galt6 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 | |
| 406411 | rhoaa | ras homolog gene family, member Aa | |
| 406659 | rhoac | ras homolog gene family, member Ac | |
| 555941 | cacna1ba | calcium channel, voltage-dependent, N type, alpha 1B subunit, a | |
| 724080 | b4galt5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | |
| 100006041 | rhoab | ras homolog gene family, member Ab |
| Gene ID | Gene Symbol | Description | Source | Organism |
|---|---|---|---|---|
| 446703 | b4galt5.L | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 L homeolog | Xenopus laevis (African clawed frog) | |
| 548965 | b4galt6 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 | Xenopus tropicalis (tropical clawed frog) | |
| 549139 | b4galt5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | Xenopus tropicalis (tropical clawed frog) | |
| 779435 | b4galt6.L | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 L homeolog | Xenopus laevis (African clawed frog) | |
| 108695277 | b4galt6.S | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 S homeolog | Xenopus laevis (African clawed frog) | |
| 108702589 | b4galt5.S | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 S homeolog | Xenopus laevis (African clawed frog) |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 175076 | ace-3 | Carboxylic ester hydrolase | |
| 176282 | lin-12 | lin-12/Notch intracellular domain | |
| 176286 | glp-1 | glp-1/Notch intracellular domain | |
| 177044 | smf-3 | NRAMP-like transporter smf-3 | |
| 177372 | cpi-1 | Cystatin cpi-1 | |
| 178748 | zmp-3 | Matrix metalloproteinase-C | |
| 179053 | cpr-4 | Cathepsin B-like cysteine proteinase 4 | |
| 179991 | zmp-4 | Hemopexin;Peptidase metallopeptidase domain-containing protein | |
| 180033 | cpr-3 | Cathepsin B-like cysteine proteinase 3 | |
| 180349 | grd-2 | Ground-like domain-containing protein |
