GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **1101 - 1125** of **2090** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▲	Organism
Regulation of BACH1 activity	Cullin-1 E3 ubiquitin-protein ligase RBX1 F-box/LRR-repeat protein 17 Polyubiquitin-B Polyubiquitin-C S-phase kinase-associated protein 1 S-phase kinase-associated protein 2 Transcription factor MafK Transcription regulator protein BACH1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O14867 O60675 P0CG47 P0CG48 P62877 P62979 P62987 P63208 Q13309 Q13616 Q9UF56	BACH1 CUL1 EMC19 FBL17 FBX13 FBXL1 FBXL17 FBXO13 MAFK OCP2 RBX1 RNF75 ROC1 RPS27A SKP1 SKP1A SKP2 TCEB1L UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Homo sapiens (human)
Regulation of HMOX1 expression and activity	Heme oxygenase 1 Minor histocompatibility antigen H13 Nuclear factor erythroid 2-related factor 2 Transcription factor MafK Transcription regulator protein BACH1	O14867 O60675 P09601 Q16236 Q8TCT9	BACH1 H13 HM13 HMOX1 HO HO1 IMP1 MAFK NFE2L2 NRF2 PSL3 SPP	Homo sapiens (human)
Integration of provirus	Barrier-to-autointegration factor Gag polyprotein Gag-Pol polyprotein High mobility group protein HMG-I/HMG-Y Importin subunit alpha-5 PC4 and SFRS1-interacting protein Peptidyl-prolyl cis-trans isomerase A Protein Rev Protein Vpr Protein Vpu Virion infectivity factor	O75475 O75531 P04585 P04591 P04618 P05919 P17096 P52294 P62937 P69723 P69726	BAF BANF1 BCRG1 CYPA DFS70 HMGA1 HMGIY KPNA1 LEDGF PPIA PSIP1 PSIP2 RCH2 gag gag-pol rev vif vpr vpu	Homo sapiens (human)
APOBEC3G mediated resistance to HIV-1 infection	Barrier-to-autointegration factor Gag polyprotein Gag-Pol polyprotein High mobility group protein HMG-I/HMG-Y PC4 and SFRS1-interacting protein Peptidyl-prolyl cis-trans isomerase A Protein Rev Protein Vpr Protein Vpu Virion infectivity factor	O75475 O75531 P04585 P04591 P04618 P05919 P17096 P62937 P69723 P69726	BAF BANF1 BCRG1 CYPA DFS70 HMGA1 HMGIY LEDGF PPIA PSIP1 PSIP2 gag gag-pol rev vif vpr vpu	Homo sapiens (human)
2-LTR circle formation	Barrier-to-autointegration factor DNA ligase 4 DNA repair protein XRCC4 Gag polyprotein Gag-Pol polyprotein High mobility group protein HMG-I/HMG-Y PC4 and SFRS1-interacting protein Protein Rev Protein Vpr Protein Vpu Virion infectivity factor X-ray repair cross-complementing protein 5 X-ray repair cross-complementing protein 6	O75475 O75531 P04585 P04591 P04618 P05919 P12956 P13010 P17096 P49917 P69723 P69726 Q13426	BAF BANF1 BCRG1 DFS70 G22P1 G22P2 HMGA1 HMGIY LEDGF LIG4 PSIP1 PSIP2 XRCC4 XRCC5 XRCC6 gag gag-pol rev vif vpr vpu	Homo sapiens (human)
Integration of viral DNA into host genomic DNA	Barrier-to-autointegration factor Gag polyprotein Gag-Pol polyprotein High mobility group protein HMG-I/HMG-Y PC4 and SFRS1-interacting protein Protein Rev Protein Vpr Protein Vpu Virion infectivity factor	O75475 O75531 P04585 P04591 P04618 P05919 P17096 P69723 P69726	BAF BANF1 BCRG1 DFS70 HMGA1 HMGIY LEDGF PSIP1 PSIP2 gag gag-pol rev vif vpr vpu	Homo sapiens (human)
Autointegration results in viral DNA circles	Barrier-to-autointegration factor Gag polyprotein Gag-Pol polyprotein High mobility group protein HMG-I/HMG-Y PC4 and SFRS1-interacting protein Protein Rev Protein Vpr Protein Vpu Virion infectivity factor	O75475 O75531 P04585 P04591 P04618 P05919 P17096 P69723 P69726	BAF BANF1 BCRG1 DFS70 HMGA1 HMGIY LEDGF PSIP1 PSIP2 gag gag-pol rev vif vpr vpu	Homo sapiens (human)
Nuclear Envelope Breakdown	Barrier-to-autointegration factor Emerin Inner nuclear membrane protein Man1 LEM domain-containing protein 2 Serine/threonine-protein kinase VRK1	O75531 P50402 Q8NC56 Q99986 Q9Y2U8	BAF BANF1 BCRG1 EDMD EMD LEMD2 LEMD3 MAN1 STA VRK1	Homo sapiens (human)
Chromatin modifying enzymes	Bromodomain and WD repeat-containing protein 1 Histone H3.1 Histone H3.2 Protein-arginine deiminase type-1 Protein-arginine deiminase type-2 Protein-arginine deiminase type-3 Protein-arginine deiminase type-4 Protein-arginine deiminase type-6 Transcription activator BRG1	P51532 P68431 Q6TGC4 Q71DI3 Q9NSI6 Q9ULC6 Q9ULW8 Q9UM07 Q9Y2J8	BAF190A BRG1 BRWD1 C21orf107 H3C1 H3C10 H3C11 H3C12 H3C13 H3C14 H3C15 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 H3F2 H3FA H3FB H3FC HIST1H3C H3FD H3FF H3FH H3FI H3FJ H3FK H3FL H3FM HIST1H3A HIST1H3B HIST1H3D HIST1H3E HIST1H3F HIST1H3G HIST1H3H HIST1H3I HIST1H3J HIST2H3A HIST2H3C HIST2H3D KIAA0994 PAD1 PAD2 PAD3 PAD4 PAD6 PADI1 PADI2 PADI3 PADI4 PADI5 PADI6 PDI1 PDI2 PDI3 PDI5 SMARCA4 SNF2B SNF2L4 WDR9	Homo sapiens (human)
Signaling by FGFR1 in disease	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 BAG family molecular chaperone regulator 4 Breakpoint cluster region protein Centrosomal protein 43 Cleavage and polyadenylation specificity factor subunit 6 Erlin-2 FGFR1 oncogene partner 2 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 4 Fibroblast growth factor 6 Fibroblast growth factor 9 Fibroblast growth factor receptor 1 Fibroblast growth factor receptor substrate 2 GRB2-associated-binding protein 1 GTPase HRas GTPase NRas Homeobox protein cut-like 1 Leucine-rich repeat flightless-interacting protein 1 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Son of sevenless homolog 1 Transcription intermediary factor 1-alpha Unconventional myosin-XVIIIa Zinc finger MYM-type protein 2	O15164 O94905 O95429 O95684 P01111 P01112 P05230 P08620 P09038 P10767 P11274 P11362 P19174 P27986 P31371 P39880 P42336 Q07889 Q13480 Q16630 Q32MZ4 Q8WU20 Q92614 Q9GZV9 Q9NP95 Q9NVK5 Q9UBW7	BAG4 BCR BCR1 BFGFR C8orf2 CD245 CEK CEP43 CFIM68 CPSF6 CUTL1 CUX1 D22S11 ERLIN2 FGF1 FGF2 FGF20 FGF23 FGF4 FGF6 FGF9 FGFA FGFB FGFBR FGFR1 FGFR1OP FGFR1OP2 FIM FLG FLT2 FOP FRS2 GAB1 GCF2 GRB1 HBGFR HRAS HRAS1 HST HST2 HSTF1 HSTF2 HYPF KIAA0216 KS3 LRRFIP1 MYO18A MYSPDZ NRAS PIK3CA PIK3R1 PLC1 PLCG1 RAMP RNF82 SODD SOS1 SPFH2 TIAF1 TIF1 TIF1A TRIM24 TRIP ZMYM2 ZNF198	Homo sapiens (human)
Signaling by plasma membrane FGFR1 fusions	BAG family molecular chaperone regulator 4 Erlin-2 Fibroblast growth factor receptor 1	O94905 O95429 P11362	BAG4 BFGFR C8orf2 CEK ERLIN2 FGFBR FGFR1 FLG FLT2 HBGFR SODD SPFH2	Homo sapiens (human)
Pyroptosis	Apoptosis regulator BAX Bcl-2 homologous antagonist/killer Caspase-1 Caspase-3 Caspase-4 Caspase-5 Cellular tumor antigen p53 Charged multivesicular body protein 2a Charged multivesicular body protein 2b Charged multivesicular body protein 3 Charged multivesicular body protein 4a Charged multivesicular body protein 4b Charged multivesicular body protein 4c Charged multivesicular body protein 6 Charged multivesicular body protein 7 Cytochrome c Gasdermin-D Gasdermin-E Granzyme B High mobility group protein B1 Interferon regulatory factor 1 Interferon regulatory factor 2 Interleukin-1 alpha Interleukin-1 beta Interleukin-18 Neutrophil elastase Tumor protein 63	O43633 O60443 P01583 P01584 P04637 P08246 P09429 P10144 P10914 P14316 P29466 P42574 P49662 P51878 P57764 P99999 Q07812 Q14116 Q16611 Q8WUX9 Q96CF2 Q96FZ7 Q9BY43 Q9H3D4 Q9H444 Q9UQN3 Q9Y3E7	BAK BAK1 BAX BC2 BCL2L4 BCL2L7 C14orf123 C20orf178 CASP1 CASP3 CASP4 CASP5 CDN1 CGI149 CGL1 CHMP2 CHMP2A CHMP2B CHMP3 CHMP4A CHMP4B CHMP4C CHMP6 CHMP7 CPP32 CSPB CTLA1 CYC CYCS DFNA5 DFNA5L ELA2 ELANE GRB GSDMD GSDMDC1 GSDME GZMB HMG1 HMGB1 ICERE1 ICH2 ICH3 IGIF IL18 IL1A IL1B IL1BC IL1BCE IL1F1 IL1F2 IL1F4 IRF1 IRF2 KET NEDF P53 P63 P73H P73L SHAX1 SHAX2 SHAX3 TP53 TP63 TP73L VPS20 VPS24	Homo sapiens (human)
Release of apoptotic factors from the mitochondria	Apoptosis regulator BAX Bcl-2 homologous antagonist/killer Cytochrome c Diablo IAP-binding mitochondrial protein Gasdermin-D Gasdermin-E	O60443 P57764 P99999 Q07812 Q16611 Q9NR28	BAK BAK1 BAX BCL2L4 BCL2L7 CDN1 CYC CYCS DFNA5 DFNA5L DIABLO GSDMD GSDMDC1 GSDME ICERE1 SMAC	Homo sapiens (human)
Activation and oligomerization of BAK protein	BH3-interacting domain death agonist Bcl-2 homologous antagonist/killer	P55957 Q16611	BAK BAK1 BCL2L7 BID CDN1	Homo sapiens (human)
Digestion of dietary lipid	Bile salt-activated lipase Colipase Gastric triacylglycerol lipase Inactive pancreatic lipase-related protein 1 Pancreatic lipase-related protein 2 Pancreatic lipase-related protein 3 Pancreatic triacylglycerol lipase	P04118 P07098 P16233 P19835 P54315 P54317 Q17RR3	BAL CEL CLPS LIPF PLRP1 PLRP2 PNLIP PNLIPRP1 PNLIPRP2 PNLIPRP3	Homo sapiens (human)
Cellular response to mitochondrial stress	ATP-dependent zinc metalloprotease YME1L1 DAP3-binding cell death enhancer 1 Eukaryotic translation initiation factor 2 subunit 1 Eukaryotic translation initiation factor 2 subunit 2 Eukaryotic translation initiation factor 2 subunit 3 Eukaryotic translation initiation factor 2-alpha kinase 1 Metalloendopeptidase OMA1, mitochondrial Prohibitin-2 Stomatin-like protein 2, mitochondrial	P05198 P20042 P41091 Q14154 Q96E52 Q96TA2 Q99623 Q9BQI3 Q9UJZ1	BAP DELE DELE1 EIF2A EIF2AK1 EIF2B EIF2G EIF2S1 EIF2S2 EIF2S3 FTSH1 HRI KIAA0141 KIAA1369 MPRP1 OMA1 PHB2 REA SLP2 STOML2 YME1L YME1L1	Homo sapiens (human)
SUMOylation of transcription cofactors	C-terminal-binding protein 1 CASP8-associated protein 2 CREB-binding protein Chromobox protein homolog 2 Chromobox protein homolog 8 Death domain-associated protein 6 E3 SUMO-protein ligase CBX4 E3 SUMO-protein ligase PIAS1 E3 SUMO-protein ligase PIAS3 E3 SUMO-protein ligase PIAS4 E3 ubiquitin-protein ligase RING1 E3 ubiquitin-protein ligase RING2 E3 ubiquitin-protein ligase Topors E3 ubiquitin-protein ligase UHRF2 Histone acetyltransferase p300 Homeodomain-interacting protein kinase 2 Inhibitor of growth protein 2 Methyl-CpG-binding domain protein 1 Myocardin-related transcription factor A Nuclear receptor coactivator 1 Nuclear receptor coactivator 2 Nuclear receptor corepressor 2 Nuclear receptor-interacting protein 1 Nucleophosmin Paired amphipathic helix protein Sin3a Parkinson disease protein 7 Peroxisome proliferator-activated receptor gamma coactivator 1-alpha Polycomb complex protein BMI-1 Polycomb group RING finger protein 2 Polyhomeotic-like protein 1 Polyhomeotic-like protein 2 Polyhomeotic-like protein 3 Probable ATP-dependent RNA helicase DDX17 Probable ATP-dependent RNA helicase DDX5 SUMO-conjugating enzyme UBC9 Scaffold attachment factor B1 Small ubiquitin-related modifier 1 Small ubiquitin-related modifier 2 Small ubiquitin-related modifier 3 Transcription intermediary factor 1-beta Zinc finger protein 131 Zinc finger protein 350	O00257 O75925 P06748 P17844 P35226 P35227 P48552 P52739 P55854 P61956 P63165 P63279 P78364 Q06587 Q09472 Q13263 Q13363 Q14781 Q15424 Q15596 Q15788 Q8IXK0 Q8N2W9 Q8NDX5 Q92793 Q92841 Q969V6 Q96PU4 Q96ST3 Q99496 Q99497 Q9GZX5 Q9H160 Q9H2X6 Q9HC52 Q9NS56 Q9UBK2 Q9UER7 Q9UIS9 Q9UKL3 Q9Y618 Q9Y6X2	BAP1 BHLHE74 BHLHE75 BING2 BMI1 CASP8AP2 CBP CBX2 CBX4 CBX8 CREBBP CTBP CTBP1 CTG26 CXXC3 DAP6 DAXX DDX17 DDX5 DDXBP1 DING EDR1 EDR2 EDR3 EP300 FLASH G17P1 HAP HELR HET HIPI3 HIPK2 HLR1 ING1L ING2 KAP1 KIAA1315 KIAA1438 LEM6 LUN MAL MBD1 MEL18 MKL1 MRTFA NCOA1 NCOA2 NCOR2 NIRF NPM NPM1 NRIP1 P300 PARK7 PC3 PCGF2 PCGF4 PCM1 PGC1 PGC1A PH1 PH2 PH3 PHC1 PHC2 PHC3 PIAS1 PIAS3 PIAS4 PIASG PPARGC1 PPARGC1A RC1 RING1 RING1A RING1B RIP25 RNF1 RNF107 RNF110 RNF2 RNF51 RNF96 SAFB SAFB1 SIN3A SMT3A SMT3B SMT3C SMT3H1 SMT3H2 SMT3H3 SRC1 SRC2 SUMO1 SUMO2 SUMO3 TIF1B TIF2 TOPORS TP53BPL TRIM28 UBC9 UBCE9 UBE2I UBL1 UHRF2 ZBRK1 ZNF131 ZNF144 ZNF350	Homo sapiens (human)
Apoptotic execution phase	B-cell receptor-associated protein 31 Caspase-8 Dynamin-1-like protein Serine/threonine-protein kinase 24	O00429 P51572 Q14790 Q9Y6E0	BAP31 BCAP31 CASP8 DLP1 DNM1L DRP1 DXS1357E MCH5 MST3 STK24 STK3	Homo sapiens (human)
Regulation of RUNX2 expression and activity	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Bone morphogenetic protein 2 Core-binding factor subunit beta Cullin-1 E3 ubiquitin-protein ligase CHIP E3 ubiquitin-protein ligase RBX1 E3 ubiquitin-protein ligase SMURF1 Estrogen receptor Glucocorticoid receptor Glycogen synthase kinase-3 beta Homeobox protein DLX-5 Homeobox protein DLX-6 Homeobox protein MSX-2 Homeobox protein Nkx-3.2 NEDD4-like E3 ubiquitin-protein ligase WWP1 Peroxisome proliferator-activated receptor gamma coactivator 1-alpha Peroxisome proliferator-activated receptor gamma coactivator 1-beta Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 S-phase kinase-associated protein 1 S-phase kinase-associated protein 2 Signal transducer and activator of transcription 1-alpha/beta Steroid hormone receptor ERR1 Transcription factor HIVEP3 Twist-related protein 1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A5LHX3 O00231 O00232 O00233 O00487 O14818 O43242 O75832 P03372 P04150 P0CG47 P0CG48 P11474 P12643 P17980 P20618 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P35548 P35998 P40306 P42224 P43686 P48556 P49720 P49721 P49841 P51665 P55036 P56178 P56179 P60896 P60900 P61289 P62191 P62195 P62333 P62877 P62979 P62987 P63208 P78367 Q06323 Q13200 Q13309 Q13616 Q13951 Q14997 Q15008 Q15672 Q16401 Q5T1R4 Q86YN6 Q8TAA3 Q92530 Q99436 Q99460 Q9H0M0 Q9HCE7 Q9UBK2 Q9UL46 Q9UNE7 Q9UNM6	BAPX1 BHLHA38 BMP2 BMP2A C7orf76 CBFB CHIP CUL1 DLX5 DLX6 DSS1 EMC19 ERR1 ESR ESR1 ESRL1 ESRRA FBXL1 GRL GSK3B HC2 HC3 HC8 HC9 HIVEP3 HOX8 HSPC IFI5111 KBP1 KIAA0072 KIAA0077 KIAA0107 KIAA1555 KIAA1625 KRC LEM6 LMP10 LMP2 LMP7 LMPX LMPY MB1 MCB1 MECL1 MIP224 MOV34L MSS1 MSX2 NKX3-2 NKX3B NR3A1 NR3B1 NR3C1 NU OCP2 PERC PFAAP4 PGC1 PGC1A PGC1B POH1 PPARGC1 PPARGC1A PPARGC1B PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 RBX1 RING10 RING12 RNF75 ROC1 RPS27A SEM1 SHFDG1 SHFM1 SKP1 SKP1A SKP2 SMURF1 STAT1 STUB1 SUG1 SUG2 TBP1 TBP7 TCEB1L TRAP2 TWIST TWIST1 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 WWP1 X Y Y2 Z ZAS3	Homo sapiens (human)
Synthesis of bile acids and bile salts	Bile acid receptor Cholesterol 25-hydroxylase Cytochrome P450 7A1 Cytochrome P450 7B1 Nuclear receptor coactivator 1 Nuclear receptor coactivator 2 Oxysterol-binding protein 1 Oxysterol-binding protein-related protein 1 Oxysterol-binding protein-related protein 2 Oxysterol-binding protein-related protein 3 Oxysterol-binding protein-related protein 6 Oxysterol-binding protein-related protein 7 Oxysterol-binding protein-related protein 9 Retinoic acid receptor RXR-alpha	O75881 O95992 P19793 P22059 P22680 Q15596 Q15788 Q96RI1 Q96SU4 Q9BXW6 Q9BZF2 Q9BZF3 Q9H1P3 Q9H4L5	BAR BHLHE74 BHLHE75 CH25H CYP7 CYP7A1 CYP7B1 FXR HRR1 KIAA0704 KIAA0772 NCOA1 NCOA2 NR1H4 NR2B1 ORP1 ORP2 ORP3 ORP6 ORP7 ORP9 OSBP OSBP1 OSBP3 OSBP4 OSBP8 OSBPL1 OSBPL1A OSBPL1B OSBPL2 OSBPL3 OSBPL6 OSBPL7 OSBPL9 RIP14 RXRA SRC1 SRC2 TIF2	Homo sapiens (human)
Transcription of E2F targets under negative control by DREAM complex	Cell division control protein 6 homolog DNA topoisomerase 2-alpha Histone deacetylase 1 Histone-binding protein RBBP4 M-phase inducer phosphatase 1 Myc proto-oncogene protein Proliferating cell nuclear antigen Protein lin-37 homolog Protein lin-52 homolog Protein lin-54 homolog Protein lin-9 homolog Protein max Retinoblastoma-like protein 1 Retinoblastoma-like protein 2 Transcription factor Dp-1 Transcription factor Dp-2 Transcription factor E2F1 Transcription factor E2F4 Transcription factor E2F5	P01106 P11388 P12004 P28749 P30304 P61244 Q01094 Q08999 Q09028 Q13547 Q14186 Q14188 Q15329 Q16254 Q52LA3 Q5TKA1 Q6MZP7 Q96GY3 Q99741	BARA BHLHD4 BHLHE39 C14orf46 CDC18L CDC25A CDC6 CXCDC1 DP1 DP2 E2F1 E2F4 E2F5 HDAC1 KIAA2037 LIN37 LIN52 LIN54 LIN9 MAX MYC PCNA RB2 RBAP48 RBBP3 RBBP4 RBL1 RBL2 RPD3L1 TFDP1 TFDP2 TGS TOP2 TOP2A	Homo sapiens (human)
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1	Cyclin-A2 Cyclin-dependent kinase 1 Histone deacetylase 1 Histone-binding protein RBBP4 Myb-related protein B Protein lin-37 homolog Protein lin-52 homolog Protein lin-54 homolog Protein lin-9 homolog Retinoblastoma-like protein 1 Retinoblastoma-like protein 2 Transcription factor Dp-1 Transcription factor Dp-2 Transcription factor E2F1 Transcription factor E2F4 Transcription factor E2F5	P06493 P10244 P20248 P28749 Q01094 Q08999 Q09028 Q13547 Q14186 Q14188 Q15329 Q16254 Q52LA3 Q5TKA1 Q6MZP7 Q96GY3	BARA BMYB C14orf46 CCN1 CCNA CCNA2 CDC2 CDC28A CDK1 CDKN1 CXCDC1 DP1 DP2 E2F1 E2F4 E2F5 HDAC1 KIAA2037 LIN37 LIN52 LIN54 LIN9 MYBL2 P34CDC2 RB2 RBAP48 RBBP3 RBBP4 RBL1 RBL2 RPD3L1 TFDP1 TFDP2 TGS	Homo sapiens (human)
Polo-like kinase mediated events	Centromere protein F Forkhead box protein M1 G2/mitotic-specific cyclin-B1 G2/mitotic-specific cyclin-B2 Histone acetyltransferase p300 Histone-binding protein RBBP4 M-phase inducer phosphatase 1 M-phase inducer phosphatase 3 Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase Myb-related protein B Protein lin-37 homolog Protein lin-52 homolog Protein lin-54 homolog Protein lin-9 homolog Serine/threonine-protein kinase PLK1 Wee1-like protein kinase	O95067 P10244 P14635 P30291 P30304 P30307 P49454 P53350 Q08050 Q09028 Q09472 Q52LA3 Q5TKA1 Q6MZP7 Q96GY3 Q99640	BARA BMYB C14orf46 CCNB CCNB1 CCNB2 CDC25A CDC25C CENPF CXCDC1 EP300 FKHL16 FOXM1 HFH11 KIAA2037 LIN37 LIN52 LIN54 LIN9 MPP2 MYBL2 MYT1 P300 PKMYT1 PLK PLK1 RBAP48 RBBP4 TGS WEE1 WIN	Homo sapiens (human)
G0 and Early G1	Cyclin-A1 Cyclin-A2 Cyclin-dependent kinase 2 Dual specificity tyrosine-phosphorylation-regulated kinase 1A G1/S-specific cyclin-E1 G1/S-specific cyclin-E2 Histone deacetylase 1 Histone-binding protein RBBP4 Protein lin-37 homolog Protein lin-52 homolog Protein lin-54 homolog Protein lin-9 homolog Retinoblastoma-like protein 1 Retinoblastoma-like protein 2 Transcription factor Dp-1 Transcription factor Dp-2 Transcription factor E2F4 Transcription factor E2F5	O96020 P20248 P24864 P24941 P28749 P78396 Q08999 Q09028 Q13547 Q13627 Q14186 Q14188 Q15329 Q16254 Q52LA3 Q5TKA1 Q6MZP7 Q96GY3	BARA C14orf46 CCN1 CCNA CCNA1 CCNA2 CCNE CCNE1 CCNE2 CDK2 CDKN2 CXCDC1 DP1 DP2 DYRK DYRK1A E2F4 E2F5 HDAC1 KIAA2037 LIN37 LIN52 LIN54 LIN9 MNB MNBH RB2 RBAP48 RBBP4 RBL1 RBL2 RPD3L1 TFDP1 TFDP2 TGS	Homo sapiens (human)
G1/S-Specific Transcription	Cell division control protein 45 homolog Cell division control protein 6 homolog Cyclin-A1 Cyclin-dependent kinase 1 DNA polymerase alpha catalytic subunit DNA replication factor Cdt1 Dihydrofolate reductase F-box only protein 5 G1/S-specific cyclin-E1 Histone deacetylase 1 Histone-binding protein RBBP4 Origin recognition complex subunit 1 Proliferating cell nuclear antigen Protein lin-37 homolog Protein lin-52 homolog Protein lin-54 homolog Protein lin-9 homolog Retinoblastoma-like protein 1 Retinoblastoma-like protein 2 Ribonucleoside-diphosphate reductase subunit M2 Thymidine kinase, cytosolic Thymidylate synthase Transcription factor Dp-1 Transcription factor Dp-2 Transcription factor E2F1 Transcription factor E2F4 Transcription factor E2F5 Transcription factor E2F6	O75419 O75461 P00374 P04183 P04818 P06493 P09884 P12004 P24864 P28749 P31350 P78396 Q01094 Q08999 Q09028 Q13415 Q13547 Q14186 Q14188 Q15329 Q16254 Q52LA3 Q5TKA1 Q6MZP7 Q96GY3 Q99741 Q9H211 Q9UKT4	BARA C14orf46 CCNA1 CCNE CCNE1 CDC18L CDC2 CDC28A CDC45 CDC45L CDC45L2 CDC6 CDK1 CDKN1 CDT1 CXCDC1 DHFR DP1 DP2 E2F1 E2F4 E2F5 E2F6 EMI1 FBX5 FBXO5 HDAC1 KIAA2037 LIN37 LIN52 LIN54 LIN9 ORC1 ORC1L P34CDC2 PARC1 PCNA POLA POLA1 RB2 RBAP48 RBBP3 RBBP4 RBL1 RBL2 RPD3L1 RR2 RRM2 TFDP1 TFDP2 TGS TK1 TS TYMS	Homo sapiens (human)

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