GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **1501 - 1525** of **2090** in total

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Pathway Name	Protein Name ▼	UniProt ID	Gene Symbol	Organism
Hedgehog 'off' state	Adenylate cyclase type 10 Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Adenylate cyclase type 9 Centriole and centriolar satellite protein OFD1 Cytoplasmic dynein 2 heavy chain 1 G-protein coupled receptor 161 Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Intraflagellar transport protein 122 homolog Intraflagellar transport protein 140 homolog Intraflagellar transport protein 172 homolog Intraflagellar transport protein 52 homolog Intraflagellar transport protein 57 homolog Intraflagellar transport protein 88 homolog Kinesin-like protein KIF3A Kinesin-like protein KIF7 Protein fantom Protein fuzzy homolog Protein inturned Protein patched homolog 1 Protein smoothened Suppressor of fused homolog Tectonic-like complex member MKS1 Tetratricopeptide repeat protein 21B Transcriptional activator GLI3 Tubby-related protein 3 WD repeat-containing protein 19 WD repeat-containing protein 35 Zinc finger protein GLI1 Zinc finger protein GLI2 cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit gamma cAMP-dependent protein kinase type I-alpha regulatory subunit cAMP-dependent protein kinase type I-beta regulatory subunit cAMP-dependent protein kinase type II-alpha regulatory subunit cAMP-dependent protein kinase type II-beta regulatory subunit	O43306 O60266 O60503 O75386 O75665 O95622 P08151 P10070 P10071 P10644 P13861 P17612 P22612 P22694 P31321 P31323 P40145 P51828 P63092 Q08462 Q08828 Q13099 Q13635 Q2M1P5 Q5JWF2 Q68CZ1 Q7Z4L5 Q8N6U8 Q8NCM8 Q8NEZ3 Q8NFM4 Q96PN6 Q96RY7 Q99835 Q9BT04 Q9HBG6 Q9NWB7 Q9NXB0 Q9P2L0 Q9UG01 Q9ULD6 Q9UMX1 Q9Y366 Q9Y496	ADCY1 ADCY10 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 C20orf9 CXorf5 DERP8 DHC1B DHC2 DNCH2 DYH1B DYNC2H1 ESRRBL1 FTM FUZ FY GLI GLI1 GLI2 GLI3 GNAS GNAS1 GPR161 GSP HIPPI IFT121 IFT122 IFT139 IFT140 IFT144 IFT172 IFT52 IFT57 IFT88 INTU KIAA0037 KIAA0422 KIAA0511 KIAA0520 KIAA0590 KIAA1005 KIAA1060 KIAA1179 KIAA1284 KIAA1336 KIAA1638 KIAA1992 KIAA1997 KIF3 KIF3A KIF7 MKS1 NGD5 NPHP8 OFD1 PDZD6 PDZK6 PKACA PKR1 PKR2 PRKACA PRKACB PRKACG PRKAR1 PRKAR1A PRKAR1B PRKAR2 PRKAR2A PRKAR2B PTCH PTCH1 RPGRIP1L SAC SMO SMOH SPG SUFU TG737 THP TSE1 TTC10 TTC21B TUBL3 TULP3 WDR10 WDR140 WDR19 WDR35 WDTC2	Homo sapiens (human)
CREB1 phosphorylation through the activation of Adenylate Cyclase	Adenylate cyclase type 1 Adenylate cyclase type 8 Calmodulin-1 cAMP-dependent protein kinase catalytic subunit PRKX cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit gamma cAMP-dependent protein kinase type I-alpha regulatory subunit cAMP-dependent protein kinase type I-beta regulatory subunit cAMP-dependent protein kinase type II-alpha regulatory subunit cAMP-dependent protein kinase type II-beta regulatory subunit	P0DP23 P10644 P13861 P17612 P22612 P22694 P31321 P31323 P40145 P51817 Q08828	ADCY1 ADCY8 CALM CALM1 CAM CAM1 PKACA PKR1 PKR2 PKX1 PRKACA PRKACB PRKACG PRKAR1 PRKAR1A PRKAR1B PRKAR2 PRKAR2A PRKAR2B PRKX TSE1	Homo sapiens (human)
PKA activation in glucagon signalling	Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Adenylate cyclase type 9 Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas Guanine nucleotide-binding protein G(s) subunit alpha isoforms short cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit gamma cAMP-dependent protein kinase type I-alpha regulatory subunit cAMP-dependent protein kinase type I-beta regulatory subunit cAMP-dependent protein kinase type II-alpha regulatory subunit cAMP-dependent protein kinase type II-beta regulatory subunit	O43306 O60266 O60503 O95622 P10644 P13861 P17612 P22612 P22694 P31321 P31323 P40145 P51828 P63092 Q08462 Q08828 Q5JWF2 Q8NFM4	ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 GNAS GNAS1 GSP KIAA0037 KIAA0422 KIAA0511 KIAA0520 KIAA1060 PKACA PKR1 PKR2 PRKACA PRKACB PRKACG PRKAR1 PRKAR1A PRKAR1B PRKAR2 PRKAR2A PRKAR2B TSE1	Homo sapiens (human)
Adenylate cyclase activating pathway	Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Adenylate cyclase type 9 Guanine nucleotide-binding protein G(olf) subunit alpha	O43306 O60266 O60503 O95622 P38405 P40145 P51828 Q08462 Q08828 Q8NFM4	ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 GNAL KIAA0037 KIAA0422 KIAA0511 KIAA0520 KIAA1060	Homo sapiens (human)
Adenylate cyclase inhibitory pathway	Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Adenylate cyclase type 9 Guanine nucleotide-binding protein G(i) subunit alpha-1 Guanine nucleotide-binding protein G(i) subunit alpha-2 Guanine nucleotide-binding protein G(i) subunit alpha-3 Guanine nucleotide-binding protein G(olf) subunit alpha Guanine nucleotide-binding protein G(t) subunit alpha-3	A8MTJ3 O43306 O60266 O60503 O95622 P04899 P08754 P38405 P40145 P51828 P63096 Q08462 Q08828 Q8NFM4	ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 GNAI1 GNAI2 GNAI2B GNAI3 GNAL GNAT3 KIAA0037 KIAA0422 KIAA0511 KIAA0520 KIAA1060	Homo sapiens (human)
Glucagon signaling in metabolic regulation	Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Adenylate cyclase type 9 Glucagon receptor Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Guanine nucleotide-binding protein subunit beta-4 Pro-glucagon	O43306 O60262 O60266 O60503 O95622 P01275 P16520 P40145 P47871 P50150 P50151 P51828 P59768 P61952 P62873 P62879 P63092 P63215 P63218 Q08462 Q08828 Q5JWF2 Q8NFM4 Q9HAV0 Q9P2W3 Q9UBI6 Q9UK08	ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 GCG GCGR GNAS GNAS1 GNB1 GNB2 GNB3 GNB4 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT10 GNGT11 GNGT3 GNGT4 GNGT5 GNGT7 GNGT9 GSP KIAA0037 KIAA0422 KIAA0511 KIAA0520 KIAA1060	Homo sapiens (human)
GPER1 signaling	Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Adenylate cyclase type 9 G-protein coupled estrogen receptor 1 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(i) subunit alpha-1 Guanine nucleotide-binding protein G(i) subunit alpha-2 Guanine nucleotide-binding protein G(i) subunit alpha-3 Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Guanine nucleotide-binding protein G(t) subunit alpha-3 Guanine nucleotide-binding protein G(z) subunit alpha Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Integrin alpha-5 Integrin beta-1 Proto-oncogene tyrosine-protein kinase Src cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit gamma cAMP-dependent protein kinase type I-alpha regulatory subunit cAMP-dependent protein kinase type I-beta regulatory subunit cAMP-dependent protein kinase type II-alpha regulatory subunit cAMP-dependent protein kinase type II-beta regulatory subunit	A8MTJ3 O14610 O14775 O43306 O60262 O60266 O60503 O95622 P04899 P05556 P08648 P08754 P10644 P12931 P13861 P16520 P17612 P19086 P22612 P22694 P31321 P31323 P40145 P50150 P50151 P51828 P59768 P61952 P62873 P62879 P63092 P63096 P63211 P63215 P63218 Q08462 Q08828 Q5JWF2 Q8NFM4 Q99527 Q9HAV0 Q9P2W3 Q9UBI6 Q9UK08	ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 CEPR CMKRL2 DRY12 FNRA FNRB GNAI1 GNAI2 GNAI2B GNAI3 GNAS GNAS1 GNAT3 GNAZ GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 GPER GPER1 GPR30 GSP ITGA5 ITGB1 KIAA0037 KIAA0422 KIAA0511 KIAA0520 KIAA1060 MDF2 MSK12 PKACA PKR1 PKR2 PRKACA PRKACB PRKACG PRKAR1 PRKAR1A PRKAR1B PRKAR2 PRKAR2A PRKAR2B SRC SRC1 TSE1	Homo sapiens (human)
PKA activation	Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Adenylate cyclase type 9 Calmodulin-1 Neurobeachin cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit gamma cAMP-dependent protein kinase type I-alpha regulatory subunit cAMP-dependent protein kinase type I-beta regulatory subunit cAMP-dependent protein kinase type II-alpha regulatory subunit cAMP-dependent protein kinase type II-beta regulatory subunit	O43306 O60266 O60503 O95622 P0DP23 P10644 P13861 P17612 P22612 P22694 P31321 P31323 P40145 P51828 Q08462 Q08828 Q8NFM4 Q8NFP9	ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 BCL8B CALM CALM1 CAM CAM1 KIAA0037 KIAA0422 KIAA0511 KIAA0520 KIAA1060 KIAA1544 LYST2 NBEA PKACA PKR1 PKR2 PRKACA PRKACB PRKACG PRKAR1 PRKAR1A PRKAR1B PRKAR2 PRKAR2A PRKAR2B TSE1	Homo sapiens (human)
Vasopressin regulates renal water homeostasis via Aquaporins	Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Adenylate cyclase type 9 Aquaporin-1 Aquaporin-2 Aquaporin-3 Aquaporin-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Rab11 family-interacting protein 2 Ras-related protein Rab-11A Unconventional myosin-Vb Vasopressin V2 receptor Vasopressin-neurophysin 2-copeptin cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit gamma cAMP-dependent protein kinase type I-alpha regulatory subunit cAMP-dependent protein kinase type I-beta regulatory subunit cAMP-dependent protein kinase type II-alpha regulatory subunit cAMP-dependent protein kinase type II-beta regulatory subunit	O14610 O14775 O43306 O60262 O60266 O60503 O95622 P01185 P10644 P13861 P16520 P17612 P22612 P22694 P29972 P30518 P31321 P31323 P40145 P41181 P50150 P50151 P51828 P55087 P59768 P61952 P62491 P62873 P62879 P63092 P63211 P63215 P63218 Q08462 Q08828 Q5JWF2 Q7L804 Q8NFM4 Q92482 Q9HAV0 Q9P2W3 Q9UBI6 Q9UK08 Q9ULV0	ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 ADHR AQP1 AQP2 AQP3 AQP4 ARVP AVP AVPR2 CHIP28 DIR DIR3 GNAS GNAS1 GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 GSP KIAA0037 KIAA0422 KIAA0511 KIAA0520 KIAA0941 KIAA1060 KIAA1119 MYO5B PKACA PKR1 PKR2 PRKACA PRKACB PRKACG PRKAR1 PRKAR1A PRKAR1B PRKAR2 PRKAR2A PRKAR2B RAB11 RAB11A RAB11FIP2 TSE1 V2R VP	Homo sapiens (human)
G alpha (z) signalling events	Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Adenylate cyclase type 9 Alpha-2A adrenergic receptor Alpha-2B adrenergic receptor Alpha-2C adrenergic receptor Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(i) subunit alpha-1 Guanine nucleotide-binding protein G(i) subunit alpha-2 Guanine nucleotide-binding protein G(i) subunit alpha-3 Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Guanine nucleotide-binding protein G(t) subunit alpha-3 Guanine nucleotide-binding protein G(z) subunit alpha Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Protein kinase C alpha type Protein kinase C beta type Protein kinase C delta type Protein kinase C epsilon type Protein kinase C eta type Protein kinase C gamma type Protein kinase C theta type Regulator of G-protein signaling 16 Regulator of G-protein signaling 17 Regulator of G-protein signaling 19 Regulator of G-protein signaling 20 Regulator of G-protein signaling 4 Regulator of G-protein signaling protein-like	A5PLK6 A8MTJ3 O14610 O14775 O15492 O43306 O60262 O60266 O60503 O76081 O95622 P04899 P05129 P05771 P08754 P08913 P16520 P17252 P18089 P18825 P19086 P24723 P40145 P49795 P49798 P50150 P50151 P51828 P59768 P61952 P62873 P62879 P63092 P63096 P63211 P63215 P63218 Q02156 Q04759 Q05655 Q08462 Q08828 Q5JWF2 Q8NFM4 Q9HAV0 Q9P2W3 Q9UBI6 Q9UGC6 Q9UK08	ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 ADRA2A ADRA2B ADRA2C ADRA2L1 ADRA2L2 ADRA2R ADRA2RL1 ADRA2RL2 ADRAR GAIP GNAI1 GNAI2 GNAI2B GNAI3 GNAI3IP GNAS GNAS1 GNAT3 GNAZ GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 GSP KIAA0037 KIAA0422 KIAA0511 KIAA0520 KIAA1060 PKCA PKCB PKCD PKCE PKCG PKCL PRKACA PRKCA PRKCB PRKCB1 PRKCD PRKCE PRKCG PRKCH PRKCL PRKCQ PRKCT RGS16 RGS17 RGS19 RGS20 RGS4 RGSL RGSL1 RGSL2 RGSR RGSZ1 RGSZ2 ZGAP1	Homo sapiens (human)
Defective AHCY causes HMAHCHD	Adenosylhomocysteinase	P23526	AHCY SAHH	Homo sapiens (human)
Metabolism of ingested SeMet, Sec, MeSec into H2Se	Adenosylhomocysteinase Cystathionine beta-synthase Cystathionine gamma-lyase Glycine N-methyltransferase Histamine N-methyltransferase Nicotinamide N-methyltransferase S-adenosylmethionine synthase isoform type-1 Selenocysteine lyase	P23526 P32929 P35520 P40261 P50135 Q00266 Q14749 Q96I15	AHCY AMS1 CBS CTH GNMT HNMT MAT1A MATA1 NNMT SAHH SCL SCLY	Homo sapiens (human)
Sulfur amino acid metabolism	Adenosylhomocysteinase Betaine--homocysteine S-methyltransferase 1 Methionine synthase reductase Methionine synthase S-adenosylmethionine synthase isoform type-1 S-methylmethionine--homocysteine S-methyltransferase BHMT2	P23526 Q00266 Q93088 Q99707 Q9H2M3 Q9UBK8	AHCY AMS1 BHMT BHMT2 MAT1A MATA1 MTR MTRR SAHH	Homo sapiens (human)
Methylation	Adenosylhomocysteinase Arsenite methyltransferase Catechol O-methyltransferase Cytochrome P450 1A2 Glutathione S-transferase omega-1 Methionine adenosyltransferase 2 subunit beta Methionine synthase reductase Methionine synthase Methyltransferase N6AMT1 Multifunctional methyltransferase subunit TRM112-like protein Nicotinamide N-methyltransferase S-adenosylmethionine synthase isoform type-1 S-adenosylmethionine synthase isoform type-2 Thiopurine S-methyltransferase	P05177 P21964 P23526 P31153 P40261 P51580 P78417 Q00266 Q99707 Q9HBK9 Q9NZL9 Q9UBK8 Q9UI30 Q9Y5N5	AHCY AMS1 AMS2 AS3MT C21orf127 COMT CYP1A2 CYT19 GSTO1 GSTTLP28 HEMK2 KMT9 MAT1A MAT2A MAT2B MATA1 MATA2 MTR MTRR N6AMT1 NNMT PRED28 SAHH TGR TPMT TRMT112	Homo sapiens (human)
Bicarbonate transporters	Adenosylhomocysteinase 3 Anion exchange protein 2 Anion exchange protein 3 Anion exchange protein 4 Band 3 anion transport protein Electrogenic sodium bicarbonate cotransporter 1 Electrogenic sodium bicarbonate cotransporter 4 Electroneutral sodium bicarbonate exchanger 1 Sodium bicarbonate cotransporter 3 Sodium-driven chloride bicarbonate exchanger	P02730 P04920 P48751 Q2Y0W8 Q6U841 Q96HN2 Q96Q91 Q9BY07 Q9Y6M7 Q9Y6R1	AE1 AE2 AE3 AE4 AHCYL2 BT DI EPB3 EPB3L1 HKB3 KIAA0739 KIAA0828 MPB3L NBC NBC1 NBC2 NBC2B NBC3 NBC4 NBCE1 NBCN2 NBCn1 NCBE NDCBE1 SBC2 SBC5 SLC4A1 SLC4A10 SLC4A2 SLC4A3 SLC4A4 SLC4A5 SLC4A6 SLC4A7 SLC4A8 SLC4A9	Homo sapiens (human)
ADORA2B mediated anti-inflammatory cytokines production	Adenosine receptor A2b Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Adenylate cyclase type 9 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(i) subunit alpha-1 Guanine nucleotide-binding protein G(i) subunit alpha-2 Guanine nucleotide-binding protein G(i) subunit alpha-3 Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Guanine nucleotide-binding protein G(t) subunit alpha-3 Guanine nucleotide-binding protein G(z) subunit alpha Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Interleukin-6 cAMP-dependent protein kinase catalytic subunit PRKX cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit gamma cAMP-dependent protein kinase type I-alpha regulatory subunit cAMP-dependent protein kinase type I-beta regulatory subunit cAMP-dependent protein kinase type II-alpha regulatory subunit cAMP-dependent protein kinase type II-beta regulatory subunit	A8MTJ3 O14610 O14775 O43306 O60262 O60266 O60503 O95622 P04899 P05231 P08754 P10644 P13861 P16520 P17612 P19086 P22612 P22694 P29275 P31321 P31323 P40145 P50150 P50151 P51817 P51828 P59768 P61952 P62873 P62879 P63092 P63096 P63211 P63215 P63218 Q08462 Q08828 Q5JWF2 Q8NFM4 Q9HAV0 Q9P2W3 Q9UBI6 Q9UK08	ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 ADORA2B GNAI1 GNAI2 GNAI2B GNAI3 GNAS GNAS1 GNAT3 GNAZ GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 GSP IFNB2 IL6 KIAA0037 KIAA0422 KIAA0511 KIAA0520 KIAA1060 PKACA PKR1 PKR2 PKX1 PRKACA PRKACB PRKACG PRKAR1 PRKAR1A PRKAR1B PRKAR2 PRKAR2A PRKAR2B PRKX TSE1	Homo sapiens (human)
NGF-independant TRKA activation	Adenosine receptor A2a BDNF/NT-3 growth factors receptor High affinity nerve growth factor receptor Pituitary adenylate cyclase-activating polypeptide type I receptor Pituitary adenylate cyclase-activating polypeptide	P04629 P18509 P29274 P41586 Q16620	ADCYAP1 ADCYAP1R1 ADORA2 ADORA2A MTC NTRK1 NTRK2 TRK TRKA TRKB	Homo sapiens (human)
Adenosine P1 receptors	Adenosine receptor A1 Adenosine receptor A2a Adenosine receptor A2b Adenosine receptor A3	P0DMS8 P29274 P29275 P30542	ADORA1 ADORA2 ADORA2A ADORA2B ADORA3	Homo sapiens (human)
Abacavir metabolism	Adenosine deaminase-like protein Alcohol dehydrogenase 1A Cytosolic purine 5'-nucleotidase Phosphoenolpyruvate carboxykinase, cytosolic [GTP]	P07327 P35558 P49902 Q6DHV7	ADAL ADAL1 ADH1 ADH1A NT5B NT5C2 NT5CP PCK1 PEPCK1 PNT5	Homo sapiens (human)
Defective ADA disrupts (deoxy)adenosine deamination	Adenosine deaminase	P00813	ADA ADA1	Homo sapiens (human)
Ribavirin ADME	Adenosine deaminase Adenosine kinase Cytosolic purine 5'-nucleotidase Equilibrative nucleoside transporter 1 Equilibrative nucleoside transporter 3 Inosine triphosphate pyrophosphatase Nucleoside diphosphate kinase A Nucleoside diphosphate kinase B Purine nucleoside phosphorylase Sodium/nucleoside cotransporter 2 Solute carrier family 28 member 3	O43868 P00491 P00813 P15531 P22392 P49902 P55263 Q99808 Q9BY32 Q9BZD2 Q9HAS3	ADA ADA1 ADK C20orf37 CNT2 CNT3 ENT1 ENT3 ITPA NDPKA NM23 NM23B NME1 NME2 NP NT5B NT5C2 NT5CP PNP PNT5 SLC28A2 SLC28A3 SLC29A1 SLC29A3	Homo sapiens (human)
Surfactant metabolism	Adenosine deaminase 2 Adenosine receptor A2a Adenosine receptor A2b Adhesion G protein-coupled receptor F5 Alpha-2A adrenergic receptor Alpha-2C adrenergic receptor Cytokine receptor common subunit beta Cytoskeleton-associated protein 4 Deleted in malignant brain tumors 1 protein Granulocyte-macrophage colony-stimulating factor receptor subunit alpha LIM and cysteine-rich domains protein 1 Napsin-A P2Y purinoceptor 2 Palmitoyltransferase ZDHHC2 Pepsin A-3 Pepsin A-4 Pepsin A-5 Phospholipid-transporting ATPase ABCA3 Pro-cathepsin H Pulmonary surfactant-associated protein A1 Pulmonary surfactant-associated protein A2 Pulmonary surfactant-associated protein B Pulmonary surfactant-associated protein D Sodium-dependent phosphate transport protein 2A Sodium-dependent phosphate transport protein 2B Surfactant protein C Surfactant-associated protein 3 Thyroid transcription factor 1-associated protein 26 Transcription factor GATA-6 Transcription termination factor 1	O95436 O96009 P07988 P08913 P09668 P0C7M3 P0DJD7 P0DJD8 P0DJD9 P11686 P15509 P18825 P29274 P29275 P32927 P35247 P41231 Q06495 Q07065 Q15361 Q8IWL1 Q8IWL2 Q8IZF2 Q92908 Q99758 Q9NZK5 Q9NZU5 Q9P031 Q9UGM3 Q9UIJ5	ABC3 ABCA3 ADA2 ADGF ADGRF5 ADORA2 ADORA2A ADORA2B ADRA2A ADRA2C ADRA2L2 ADRA2R ADRA2RL2 ADRAR BR22 CCDC59 CECR1 CKAP4 COLEC4 COLEC5 COLEC7 CPSB CSF2R CSF2RA CSF2RB CSF2RY CTSH DMBT1 GATA6 GP340 GPR116 IDGFL IL3RB IL5RB KIAA0758 LMCD1 NAP1 NAPA NAPSA NPT2 P2RU1 P2RY2 PGA3 PGA4 PGA5 PSAP PSPD REAM REC SFTA3 SFTP1 SFTP2 SFTP3 SFTP4 SFTPA SFTPA1 SFTPA1B SFTPA2 SFTPA2B SFTPB SFTPC SFTPD SFTPH SLC17A2 SLC34A1 SLC34A2 TAP26 TTF1 ZDHHC2 ZNF372	Homo sapiens (human)
Regulation of MITF-M-dependent genes involved in apoptosis	Adenosine 5'-monophosphoramidase HINT1 Apoptosis regulator Bcl-2 Baculoviral IAP repeat-containing protein 7 Bcl-2-related protein A1 Endoribonuclease Dicer Helicase MOV-10 Histone deacetylase 1 POU domain, class 3, transcription factor 2 Paired amphipathic helix protein Sin3a Protein argonaute-1 Protein argonaute-2 Protein argonaute-3 Protein argonaute-4 Transient receptor potential cation channel subfamily M member 1 Trinucleotide repeat-containing gene 6A protein Trinucleotide repeat-containing gene 6B protein Trinucleotide repeat-containing gene 6C protein	P10415 P20265 P49773 Q13547 Q16548 Q7Z4N2 Q8NDV7 Q96CA5 Q96ST3 Q9H9G7 Q9HCE1 Q9HCJ0 Q9HCK5 Q9UKV8 Q9UL18 Q9UPQ9 Q9UPY3	AGO1 AGO2 AGO3 AGO4 BCL2 BCL2A1 BCL2L5 BFL1 BIRC7 BRN2 CAGH26 DICER DICER1 EIF2C1 EIF2C2 EIF2C3 EIF2C4 GRS HBPA1 HDAC1 HERNA HINT HINT1 KIAA0928 KIAA1093 KIAA1460 KIAA1567 KIAA1582 KIAA1631 KIAP LIVIN LTRPC1 MLIAP MLSN MLSN1 MOV10 OCT7 OTF7 PKCI1 POU3F2 PRKCNH1 RNF50 RPD3L1 SIN3A TNRC6 TNRC6A TNRC6B TNRC6C TRPM1	Homo sapiens (human)
Transcriptional and post-translational regulation of MITF-M expression and activity	Adenosine 5'-monophosphoramidase HINT1 Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 Arginine--tRNA ligase, cytoplasmic Aspartate--tRNA ligase, cytoplasmic Bifunctional glutamate/proline--tRNA ligase CREB-binding protein Catenin beta-1 Eukaryotic translation elongation factor 1 epsilon-1 Exportin-1 Forkhead box protein D3 Glutamine--tRNA ligase Glycogen synthase kinase-3 beta Homeobox protein aristaless-like 3 Isoleucine--tRNA ligase, cytoplasmic Leucine--tRNA ligase, cytoplasmic Lymphoid enhancer-binding factor 1 Lysine--tRNA ligase Mast/stem cell growth factor receptor Kit Melanocortin receptor 3 Melanocortin receptor 4 Melanocortin receptor 5 Melanocyte-stimulating hormone receptor Methionine--tRNA ligase, cytoplasmic Microphthalmia-associated transcription factor Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 POU domain, class 3, transcription factor 2 Paired box protein Pax-3 Pro-opiomelanocortin Protein Wnt-3a Ribosomal protein S6 kinase alpha-1 Transcription factor E3 Transcription factor EB Transcription factor EC Transcription factor SOX-10 Transcription factor SOX-2	O14948 O14980 O43324 O75030 O95076 P01189 P07814 P10721 P14868 P19484 P19532 P20265 P23760 P27361 P28482 P32245 P33032 P35222 P41252 P41968 P47897 P48431 P49773 P49841 P54136 P56192 P56693 P56704 Q01726 Q12904 Q13155 Q15046 Q15418 Q92793 Q9P2J5 Q9UJU2 Q9UJU5	AIMP1 AIMP2 AIMP3 ALX3 BHLHE32 BHLHE33 BHLHE34 BHLHE35 BRN2 CBP CREBBP CRM1 CTNNB CTNNB1 DARS DARS1 EEF1E1 EMAP2 EPRS EPRS1 ERK1 ERK2 FOXD3 GLNS GSK3B HFH2 HINT HINT1 HUP2 IARS IARS1 JTV1 KARS KARS1 KIAA0070 KIAA1352 KIT LARS LARS1 LEF1 MAPK1 MAPK3 MAPKAPK1A MARS MARS1 MC1R MC3R MC4R MC5R MITF MSHR OCT7 OTF7 P18 PARS PAX3 PKCI1 POMC POU3F2 PRKCNH1 PRKM1 PRKM2 PRKM3 QARS QARS1 QPRS RARS RARS1 RPS6KA1 RSK1 SCFR SCYE1 SOX10 SOX2 TCFEC TFE3 TFEB TFEC TFECL WNT3A XPO1	Homo sapiens (human)
Transport of nucleotide sugars	Adenosine 3'-phospho 5'-phosphosulfate transporter 1 Adenosine 3'-phospho 5'-phosphosulfate transporter 2 CMP-sialic acid transporter GDP-fucose transporter 1 Nucleotide sugar transporter SLC35B4 Nucleotide sugar transporter SLC35D1 Nucleotide sugar transporter SLC35D2 UDP-N-acetylglucosamine transporter UDP-galactose translocator	P78381 P78382 Q76EJ3 Q8TB61 Q969S0 Q96A29 Q9H1N7 Q9NTN3 Q9Y2D2	C6orf196 FUCT1 HFRC KIAA0260 PAPST1 PAPST2 SLC35A1 SLC35A2 SLC35A3 SLC35B2 SLC35B3 SLC35B4 SLC35C1 SLC35D1 SLC35D2 UGALT UGT UGTL UGTREL7 UGTREL8 YEA4	Homo sapiens (human)

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