GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **1651 - 1675** of **2090** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▲	Organism
Defective SLC11A2 causes hypochromic microcytic anemia, with iron overload 1 (AHMIO1)	Natural resistance-associated macrophage protein 2	P49281	DCT1 DMT1 NRAMP2 SLC11A2	Homo sapiens (human)
Essential pentosuria	L-xylulose reductase	Q7Z4W1	DCXR SDR20C1	Homo sapiens (human)
Z-decay: degradation of maternal mRNAs by zygotically expressed factors	DIS3-like exonuclease 2 Eukaryotic initiation factor 4A-I Eukaryotic initiation factor 4A-II Eukaryotic initiation factor 4A-III Eukaryotic translation initiation factor 4 gamma 1 Eukaryotic translation initiation factor 4B Eukaryotic translation initiation factor 4E Polyadenylate-binding protein 1 Polyadenylate-binding protein 2 Polyadenylate-binding protein-interacting protein 1 Terminal uridylyltransferase 4 Terminal uridylyltransferase 7	P06730 P11940 P23588 P38919 P60842 Q04637 Q14240 Q5TAX3 Q5VYS8 Q86U42 Q8IYB7 Q9H074	DDX2A DDX2B DDX48 DIS3L2 EIF4A EIF4A1 EIF4A2 EIF4A3 EIF4B EIF4E EIF4EL1 EIF4F EIF4G EIF4G1 EIF4GI FAM6A HS2 KIAA0111 KIAA0191 KIAA1711 PAB1 PAB2 PABP PABP1 PABP2 PABPC1 PABPC2 PABPN1 PAIP1 TUT4 TUT7 ZCCHC11 ZCCHC6	Homo sapiens (human)
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S	Eukaryotic initiation factor 4A-I Eukaryotic initiation factor 4A-II Eukaryotic translation initiation factor 4 gamma 1 Eukaryotic translation initiation factor 4B Eukaryotic translation initiation factor 4E-binding protein 1 Eukaryotic translation initiation factor 4E Eukaryotic translation initiation factor 4H	P06730 P23588 P60842 Q04637 Q13541 Q14240 Q15056	DDX2A DDX2B EIF4A EIF4A1 EIF4A2 EIF4B EIF4E EIF4EBP1 EIF4EL1 EIF4F EIF4G EIF4G1 EIF4GI EIF4H KIAA0038 WBSCR1 WSCR1	Homo sapiens (human)
DEx/H-box helicases activate type I IFN and inflammatory cytokines production	ATP-dependent DNA/RNA helicase DHX36 ATP-dependent RNA helicase A Interferon regulatory factor 7 Myeloid differentiation primary response protein MyD88 Nuclear factor NF-kappa-B p100 subunit Nuclear factor NF-kappa-B p105 subunit Transcription factor p65	P19838 Q00653 Q04206 Q08211 Q92985 Q99836 Q9H2U1	DDX36 DDX9 DHX36 DHX9 IRF7 KIAA1488 LKP LYT10 MLEL1 MYD88 NDH2 NFKB1 NFKB2 NFKB3 RELA RHAU	Homo sapiens (human)
Replication of the SARS-CoV-2 genome	Probable ATP-dependent RNA helicase DDX5 Replicase polyprotein 1a Replicase polyprotein 1ab Retinoblastoma-associated protein Zinc finger CCHC-type and RNA-binding motif-containing protein 1 von Hippel-Lindau disease tumor suppressor	P06400 P0DTC1 P0DTD1 P17844 P40337 Q8TBF4	DDX5 G17P1 HELR HLR1 RB1 VHL ZCRB1 rep	Homo sapiens (human)
HHAT G278V doesn't palmitoylate Hh-Np	Desert hedgehog protein Indian hedgehog protein Protein-cysteine N-palmitoyltransferase HHAT Sonic hedgehog protein	O43323 Q14623 Q15465 Q5VTY9	DHH HHAT IHH MART2 SHH SKI1	Homo sapiens (human)
Hypusinylation	Deoxyhypusine hydroxylase Deoxyhypusine synthase Eukaryotic translation initiation factor 5A-1 Eukaryotic translation initiation factor 5A-2	P49366 P63241 Q9BU89 Q9GZV4	DHPS DOHH DS EIF5A EIF5A2 HLRC1	Homo sapiens (human)
Sulfide oxidation to sulfate	Mitochondrial dicarboxylate carrier Persulfide dioxygenase ETHE1, mitochondrial Sulfide Sulfite oxidase, mitochondrial Thiosulfate sulfurtransferase Thiosulfate	O95571 P51687 Q16762 Q8NFU3 Q9UBX3 Q9Y6N5	DIC ETHE1 HSCO KAT SLC25A10 SQOR SQRDL SUOX TST TSTD1	Homo sapiens (human)
Translesion synthesis by POLK	DNA polymerase kappa DNA polymerase zeta catalytic subunit DNA repair protein REV1 Mitotic spindle assembly checkpoint protein MAD2B Polyubiquitin-B Polyubiquitin-C Proliferating cell nuclear antigen Replication factor C subunit 1 Replication factor C subunit 2 Replication factor C subunit 3 Replication factor C subunit 4 Replication factor C subunit 5 Replication protein A 14 kDa subunit Replication protein A 32 kDa subunit Replication protein A 70 kDa DNA-binding subunit Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O60673 P0CG47 P0CG48 P12004 P15927 P27694 P35244 P35249 P35250 P35251 P40937 P40938 P62979 P62987 Q9UBT6 Q9UBZ9 Q9UI95	DINB1 MAD2B MAD2L2 PCNA POLK POLZ REPA1 REPA2 REPA3 REV1 REV1L REV3 REV3L REV7 RFC1 RFC140 RFC2 RFC3 RFC4 RFC5 RPA1 RPA14 RPA2 RPA3 RPA32 RPA34 RPA70 RPS27A UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Homo sapiens (human)
Negative regulation of TCF-dependent signaling by WNT ligand antagonists	Dickkopf-related protein 1 Dickkopf-related protein 2 Dickkopf-related protein 4 Kremen protein 1 Kremen protein 2 Low-density lipoprotein receptor-related protein 5 Low-density lipoprotein receptor-related protein 6 Protein Wnt-3a Protein Wnt-4 Protein Wnt-5a Protein Wnt-9a Sclerostin Secreted frizzled-related protein 1 Secreted frizzled-related protein 2 Wnt inhibitory factor 1	O14904 O75197 O75581 O94907 P41221 P56704 P56705 Q8N474 Q8NCW0 Q96HF1 Q96MU8 Q9BQB4 Q9UBT3 Q9UBU2 Q9Y5W5	DKK1 DKK2 DKK4 FRP FRP1 FRP2 KREMEN KREMEN1 KREMEN2 KRM1 KRM2 LR3 LRP5 LRP6 LRP7 SARP1 SARP2 SFRP1 SFRP2 SOST WIF1 WNT14 WNT3A WNT4 WNT5A WNT9A	Homo sapiens (human)
Signaling by LRP5 mutants	Dickkopf-related protein 1 Dickkopf-related protein 2 Dickkopf-related protein 4 Kremen protein 1 Kremen protein 2 Low-density lipoprotein receptor-related protein 5	O75197 O94907 Q8NCW0 Q96MU8 Q9UBT3 Q9UBU2	DKK1 DKK2 DKK4 KREMEN KREMEN1 KREMEN2 KRM1 KRM2 LR3 LRP5 LRP7	Homo sapiens (human)
Regulation of pyruvate dehydrogenase (PDH) complex	Dihydrolipoyl dehydrogenase, mitochondrial Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial Maleylacetoacetate isomerase NAD-dependent protein lipoamidase sirtuin-4, mitochondrial Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial Pyruvate dehydrogenase E1 component subunit beta, mitochondrial Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial Pyruvate dehydrogenase protein X component, mitochondrial [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial	O00330 O43708 P08559 P09622 P10515 P11177 P29803 Q15118 Q15119 Q15120 Q16654 Q8NCN5 Q9P0J1 Q9P2J9 Q9Y6E7	DLAT DLD DLTA GCSL GSTZ1 KIAA1348 KIAA1990 LAD MAAI PDHA1 PDHA2 PDHAL PDHB PDHK1 PDHK2 PDHK3 PDHK4 PDHX PDK1 PDK2 PDK3 PDK4 PDP PDP1 PDP2 PDPR PDX1 PHE1A PHE1B PHE3 PPM2C SIR2L4 SIRT4	Homo sapiens (human)
PDH complex synthesizes acetyl-CoA from PYR	Dihydrolipoyl dehydrogenase, mitochondrial Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial Pyruvate dehydrogenase E1 component subunit beta, mitochondrial Pyruvate dehydrogenase protein X component, mitochondrial	O00330 P08559 P09622 P10515 P11177 P29803	DLAT DLD DLTA GCSL LAD PDHA1 PDHA2 PDHAL PDHB PDHX PDX1 PHE1A PHE1B PHE3	Homo sapiens (human)
Succinyl-CoA Biosynthesis	2-oxoglutarate dehydrogenase complex component E1 Alpha-ketoglutarate dehydrogenase component 4 Dihydrolipoyl dehydrogenase, mitochondrial Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial	P09622 P36957 P82909 Q02218	DLD DLST DLTS GCSL KGD4 LAD MRPS36 OGDH PHE3	Homo sapiens (human)
Removal of the Flap Intermediate	DNA polymerase alpha catalytic subunit DNA polymerase alpha subunit B DNA polymerase delta catalytic subunit DNA polymerase delta subunit 2 DNA polymerase delta subunit 3 DNA polymerase delta subunit 4 DNA primase large subunit DNA primase small subunit DNA replication ATP-dependent helicase/nuclease DNA2 Flap endonuclease 1 Proliferating cell nuclear antigen Replication protein A 14 kDa subunit Replication protein A 32 kDa subunit Replication protein A 70 kDa DNA-binding subunit	P09884 P12004 P15927 P27694 P28340 P35244 P39748 P49005 P49642 P49643 P51530 Q14181 Q15054 Q9HCU8	DNA2 DNA2L FEN1 KIAA0039 KIAA0083 PCNA POLA POLA1 POLA2 POLD POLD1 POLD2 POLD3 POLD4 POLDS PRIM1 PRIM2 PRIM2A RAD2 REPA1 REPA2 REPA3 RPA1 RPA14 RPA2 RPA3 RPA32 RPA34 RPA70	Homo sapiens (human)
Vitamin B1 (thiamin) metabolism	Mitochondrial thiamine pyrophosphate carrier Thiamin pyrophosphokinase 1 Thiamine transporter 1 Thiamine transporter 2 Thiamine-triphosphatase	O60779 Q9BU02 Q9BZV2 Q9H3S4 Q9HC21	DNC MUP1 SLC19A2 SLC19A3 SLC25A19 THT1 THTPA TPK1 TRMA	Homo sapiens (human)
Nef and signal transduction	Dedicator of cytokinesis protein 2 Engulfment and cell motility protein 1 Protein Nef Ras-related C3 botulinum toxin substrate 1 Serine/threonine-protein kinase PAK 2 Tyrosine-protein kinase Fyn Tyrosine-protein kinase HCK Tyrosine-protein kinase Lck	P04601 P06239 P06241 P08631 P63000 Q13177 Q92556 Q92608	DOCK2 ELMO1 FYN HCK KIAA0209 KIAA0281 LCK PAK2 RAC1 TC25 nef	Homo sapiens (human)
Activation of NOXA and translocation to mitochondria	Cellular tumor antigen p53 Phorbol-12-myristate-13-acetate-induced protein 1 Transcription factor Dp-1 Transcription factor Dp-2 Transcription factor E2F1	P04637 Q01094 Q13794 Q14186 Q14188	DP1 DP2 E2F1 NOXA P53 PMAIP1 RBBP3 TFDP1 TFDP2 TP53	Homo sapiens (human)
Inhibition of replication initiation of damaged DNA by RB1/E2F1	DNA polymerase alpha catalytic subunit DNA polymerase alpha subunit B DNA primase large subunit DNA primase small subunit Retinoblastoma-associated protein Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta Transcription factor Dp-1 Transcription factor Dp-2 Transcription factor E2F1	P06400 P09884 P30153 P30154 P49642 P49643 P62714 P67775 Q01094 Q14181 Q14186 Q14188 Q9Y5P8	DP1 DP2 E2F1 POLA POLA1 POLA2 PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R3B PPP2R3L PRIM1 PRIM2 PRIM2A RB1 RBBP3 TFDP1 TFDP2	Homo sapiens (human)
Defective DPAGT1 causes CDG-1j, CMSTA2	UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase	Q9H3H5	DPAGT1 DPAGT2	Homo sapiens (human)
SMAD4 MH2 Domain Mutants in Cancer	Mothers against decapentaplegic homolog 2 Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 4	P84022 Q13485 Q15796	DPC4 MADH2 MADH3 MADH4 MADR2 SMAD2 SMAD3 SMAD4	Homo sapiens (human)
SMAD2/3 MH2 Domain Mutants in Cancer	Mothers against decapentaplegic homolog 2 Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 4	P84022 Q13485 Q15796	DPC4 MADH2 MADH3 MADH4 MADR2 SMAD2 SMAD3 SMAD4	Homo sapiens (human)
Defective DPM1 causes CDG-1e	Dolichol phosphate-mannose biosynthesis regulatory protein Dolichol-phosphate mannosyltransferase subunit 1 Dolichol-phosphate mannosyltransferase subunit 3	O60762 O94777 Q9P2X0	DPM1 DPM2 DPM3	Homo sapiens (human)
Defective DPM2 causes CDG-1u	Dolichol phosphate-mannose biosynthesis regulatory protein Dolichol-phosphate mannosyltransferase subunit 1 Dolichol-phosphate mannosyltransferase subunit 3	O60762 O94777 Q9P2X0	DPM1 DPM2 DPM3	Homo sapiens (human)

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