GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **1951 - 1975** of **2090** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism	GlyTouCan ID
Calcineurin activates NFAT	Calcineurin subunit B type 1 Calmodulin-1 Nuclear factor of activated T-cells, cytoplasmic 1 Nuclear factor of activated T-cells, cytoplasmic 2 Nuclear factor of activated T-cells, cytoplasmic 3 Peptidyl-prolyl cis-trans isomerase A Peptidyl-prolyl cis-trans isomerase FKBP1A Protein phosphatase 3 catalytic subunit alpha Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform	O95644 P0DP23 P16298 P62937 P62942 P63098 Q08209 Q12968 Q13469	CALM CALM1 CALNA CALNA2 CALNB CAM CAM1 CNA CNA2 CNB CYPA FKBP1 FKBP12 FKBP1A NFAT1 NFAT2 NFAT4 NFATC NFATC1 NFATC2 NFATC3 NFATP PPIA PPP3CA PPP3CB PPP3R1	Homo sapiens (human)
APC-Cdc20 mediated degradation of Nek2A	Anaphase-promoting complex subunit 10 Anaphase-promoting complex subunit 11 Anaphase-promoting complex subunit 15 Anaphase-promoting complex subunit 16 Anaphase-promoting complex subunit 1 Anaphase-promoting complex subunit 2 Anaphase-promoting complex subunit 4 Anaphase-promoting complex subunit 5 Anaphase-promoting complex subunit 7 Anaphase-promoting complex subunit CDC26 Cell division cycle protein 16 homolog Cell division cycle protein 20 homolog Cell division cycle protein 23 homolog Cell division cycle protein 27 homolog Mitotic checkpoint protein BUB3 Mitotic checkpoint serine/threonine-protein kinase BUB1 beta Mitotic spindle assembly checkpoint protein MAD2A Polyubiquitin-B Polyubiquitin-C Serine/threonine-protein kinase Nek2 Ubiquitin-conjugating enzyme E2 C Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 E1 Ubiquitin-conjugating enzyme E2 S Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00762 O43684 O60566 P0CG47 P0CG48 P30260 P51668 P51955 P51965 P60006 P62979 P62987 Q12834 Q13042 Q13257 Q16763 Q8NHZ8 Q96DE5 Q9H1A4 Q9NYG5 Q9UJX2 Q9UJX3 Q9UJX4 Q9UJX5 Q9UJX6 Q9UM13	ANAPC1 ANAPC10 ANAPC11 ANAPC12 ANAPC15 ANAPC16 ANAPC2 ANAPC3 ANAPC4 ANAPC5 ANAPC6 ANAPC7 ANAPC8 APC10 APC2 APC4 APC5 APC7 BUB1B BUB3 BUBR1 C10orf104 C11orf51 C9orf17 CDC16 CDC20 CDC23 CDC26 CDC27 CENP-27 D0S1430E D17S978E E2EPF KIAA1406 MAD2 MAD2L1 MAD3L NEK2 NEK2A NLK1 RPS27A SFT SSK1 TSG24 UBA52 UBA80 UBB UBC UBC5A UBCEP1 UBCEP2 UBCH10 UBCH5 UBCH5A UBCH6 UBE2C UBE2D1 UBE2E1 UBE2S	Homo sapiens (human)
Activation of anterior HOX genes in hindbrain development during early embryogenesis	CCR4-NOT transcription complex subunit 6 CCR4-NOT transcription complex subunit 9 CREB-binding protein DNA-directed RNA polymerase II subunit RPB11-a DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 E3 SUMO-protein ligase EGR2 E3 SUMO-protein ligase PIAS2 Histone H2A type 1-B/E Histone H2A type 1-C Histone H2A type 1-D Histone H2A type 1-J Histone H2A type 2-A Histone H2A type 2-C Histone H2A-Bbd type 1 Histone H2A.J Histone H2A.V Histone H2AX Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/F/G/I Histone H2B type 1-D Histone H2B type 1-H Histone H2B type 1-J Histone H2B type 1-K Histone H2B type 1-L Histone H2B type 1-M Histone H2B type 1-N Histone H2B type 1-O Histone H2B type 2-E Histone H2B type 3-B Histone H2B type F-S Histone H3.1 Histone H3.2 Histone H3.3 Histone H4 Histone acetyltransferase p300 Histone deacetylase 3 Histone-binding protein RBBP4 Histone-binding protein RBBP7 Histone-lysine N-methyltransferase 2C Histone-lysine N-methyltransferase 2D Histone-lysine N-methyltransferase EZH2 Homeobox protein Hox-A1 Homeobox protein Hox-A2 Homeobox protein Hox-A3 Homeobox protein Hox-A4 Homeobox protein Hox-B1 Homeobox protein Hox-B2 Homeobox protein Hox-B3 Homeobox protein Hox-B4 Homeobox protein Hox-C4 Homeobox protein Hox-D1 Homeobox protein Hox-D3 Homeobox protein Hox-D4 Homeobox protein Meis1 Homeobox protein PKNOX1 LIM domain-containing protein ajuba Lysine-specific demethylase 6A Nuclear receptor coactivator 3 Nuclear receptor coactivator 6 Nuclear receptor corepressor 1 PAX-interacting protein 1 PAXIP1-associated glutamate-rich protein 1 Paired box protein Pax-6 Polycomb group RING finger protein 2 Polycomb protein EED Polycomb protein SUZ12 Pre-B-cell leukemia transcription factor 1 Protein dpy-30 homolog Retinoblastoma-binding protein 5 Retinoic acid receptor RXR-alpha Retinoic acid receptor alpha Retinoic acid receptor beta Retinoic acid receptor gamma Set1/Ash2 histone methyltransferase complex subunit ASH2 Transcription factor Jun Transcription factor MafB Transcriptional repressor CTCF Transcriptional repressor protein YY1 WD repeat-containing protein 5 Zinc finger protein 335	O00470 O14686 O15379 O15514 O15550 O43364 O43365 O60814 O75376 O75530 O75928 P04908 P05412 P06899 P09016 P09017 P0C5Y9 P10276 P10826 P11161 P13631 P14651 P14652 P14653 P16104 P17483 P19387 P19388 P19793 P20671 P23527 P24928 P25490 P26367 P30876 P31249 P33778 P35227 P36954 P40424 P49639 P49711 P52434 P52435 P53803 P55347 P57053 P58876 P61218 P61964 P62487 P62805 P62807 P62875 P68431 P84243 Q00056 Q09028 Q09472 Q14686 Q15022 Q15291 Q15910 Q16576 Q16777 Q16778 Q6FI13 Q6ZW49 Q71DI3 Q71UI9 Q8N257 Q8NEZ4 Q92600 Q92793 Q93077 Q93079 Q96A08 Q96IF1 Q99877 Q99878 Q99879 Q99880 Q9BTK6 Q9BTM1 Q9C005 Q9GZZ0 Q9H4Z2 Q9UBL3 Q9ULM6 Q9Y5Q3 Q9Y6Q9	AIB1 AIB3 AJUBA ALR AN2 ASH2L ASH2L1 BHLHE42 BIG3 C16orf53 CBP CCR4 CCR4a CHET9 CNOT6 CNOT9 CREBBP CTCF DPY30 EED EGR2 EP300 EZH2 H2AB1 H2AC14 H2AC18 H2AC19 H2AC20 H2AC4 H2AC6 H2AC7 H2AC8 H2AFA H2AFB1 H2AFE H2AFG H2AFJ H2AFL H2AFM H2AFO H2AFQ H2AFV H2AFX H2AJ H2AV H2AX H2AZ2 H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H2BFA H2BFB H2BFC H2BFD H2BFE H2BFF H2BFG H2BFH H2BFJ H2BFK H2BFL H2BFN H2BFQ H2BFR H2BFS H2BFT H2BS1 H2BU1 H3-3A H3-3B H3.3A H3.3B H3C1 H3C10 H3C11 H3C12 H3C13 H3C14 H3C15 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 H3F2 H3F3 H3F3A H3F3B H3FA H3FB H3FC HIST1H3C H3FD H3FF H3FH H3FI H3FJ H3FK H3FL H3FM H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HALR HAP HDAC3 HIRIP1 HIRIP2 HIST1H2AB HIST1H2AC HIST1H2AD HIST1H2AE HIST1H2AJ HIST1H2BA HIST1H2BB HIST1H2BC HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2BI HIST1H2BJ HIST1H2BK HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST1H3A HIST1H3B HIST1H3D HIST1H3E HIST1H3F HIST1H3G HIST1H3H HIST1H3I HIST1H3J HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H2AA HIST2H2AA3 HIST2H2AA4 HIST2H2AC HIST2H2BE HIST2H3A HIST2H3C HIST2H3D HIST2H4 HIST2H4A HIST2H4B HIST3H2BB HIST4H4 HOX1D HOX1E HOX1F HOX1K HOX2F HOX2G HOX2H HOX2I HOX3E HOX4 HOX4A HOX4B HOX4G HOXA1 HOXA2 HOXA3 HOXA4 HOXB1 HOXB2 HOXB3 HOXB4 HOXC4 HOXD1 HOXD3 HOXD4 INO80S JJAZ1 JUB JUN KDM6A KIAA0160 KIAA0181 KIAA1047 KIAA1194 KIAA1506 KMT2C KMT2D KMT6 KRML KROX20 MAFB MEIS1 MEL18 MLL2 MLL3 MLL4 NCOA3 NCOA6 NCOR1 NR1B1 NR1B2 NR1B3 NR2B1 P300 PA1 PAGR1 PAX6 PAXIP1 PAXIP1L PBX1 PCGF2 PIAS2 PIASX PKNOX1 POLR2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J1 POLR2K POLR2L POLRF PREP1 PRL PTIP RAC3 RAP250 RARA RARB RARG RBAP46 RBAP48 RBBP4 RBBP5 RBBP7 RBQ3 RCD1 RNF110 RPB7 RQCD1 RXRA SUZ12 TRAM1 TRBP TSH2B UTX WDR5 YY1 ZNF144 ZNF335	Homo sapiens (human)
Signaling by Leptin	Insulin receptor substrate 1 Insulin receptor substrate 2 Leptin Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Suppressor of cytokine signaling 3 Tyrosine-protein kinase JAK2 Tyrosine-protein phosphatase non-receptor type 11	O14543 O60674 P35568 P40763 P41159 P42229 P51692 Q06124 Q9Y4H2	APRF CIS3 IRS1 IRS2 JAK2 LEP OB OBS PTP2C PTPN11 SHPTP2 SOCS3 SSI3 STAT3 STAT5 STAT5A STAT5B	Homo sapiens (human)
Sealing of the nuclear envelope (NE) by ESCRT-III	Charged multivesicular body protein 2a Charged multivesicular body protein 2b Charged multivesicular body protein 3 Charged multivesicular body protein 4a Charged multivesicular body protein 4b Charged multivesicular body protein 4c Charged multivesicular body protein 6 Charged multivesicular body protein 7 Coiled-coil and C2 domain-containing protein 1B IST1 homolog LEM domain-containing protein 2 Putative tubulin-like protein alpha-4B Spastin Tubulin alpha chain-like 3 Tubulin alpha-1A chain Tubulin alpha-1B chain Tubulin alpha-1C chain Tubulin alpha-3C chain Tubulin alpha-3D chain Tubulin alpha-3E chain Tubulin alpha-4A chain Tubulin alpha-8 chain Tubulin beta 8B Tubulin beta-1 chain Tubulin beta-2A chain Tubulin beta-2B chain Tubulin beta-3 chain Tubulin beta-4A chain Tubulin beta-4B chain Tubulin beta-6 chain Tubulin beta-8 chain Vacuolar protein sorting-associated protein 4A	A6NHL2 A6NNZ2 O43633 P04350 P0DPH7 P0DPH8 P53990 P68363 P68366 P68371 Q13509 Q13885 Q3ZCM7 Q5T0F9 Q6PEY2 Q71U36 Q8NC56 Q8WUX9 Q96CF2 Q96FZ7 Q9BQE3 Q9BUF5 Q9BVA1 Q9BY43 Q9H444 Q9H4B7 Q9H853 Q9NY65 Q9UBP0 Q9UN37 Q9UQN3 Q9Y3E7	ADPSP BC2 C14orf123 C20orf178 CC2D1B CGI149 CHMP2 CHMP2A CHMP2B CHMP3 CHMP4A CHMP4B CHMP4C CHMP6 CHMP7 FSP2 IST1 KIAA0174 KIAA1083 KIAA1836 LEMD2 LGD1 NEDF SHAX1 SHAX2 SHAX3 SPAST SPG4 TUBA1 TUBA1A TUBA1B TUBA1C TUBA2 TUBA3 TUBA3C TUBA3D TUBA3E TUBA4 TUBA4A TUBA4B TUBA6 TUBA8 TUBAL2 TUBAL3 TUBB1 TUBB2 TUBB2A TUBB2B TUBB2C TUBB3 TUBB4 TUBB4A TUBB4B TUBB5 TUBB6 TUBB8 TUBB8B VPS20 VPS24 VPS4 VPS4A	Homo sapiens (human)
Release of apoptotic factors from the mitochondria	Apoptosis regulator BAX Bcl-2 homologous antagonist/killer Cytochrome c Diablo IAP-binding mitochondrial protein Gasdermin-D Gasdermin-E	O60443 P57764 P99999 Q07812 Q16611 Q9NR28	BAK BAK1 BAX BCL2L4 BCL2L7 CDN1 CYC CYCS DFNA5 DFNA5L DIABLO GSDMD GSDMDC1 GSDME ICERE1 SMAC	Homo sapiens (human)
ALPK1 signaling pathway	Alpha-protein kinase 1 Mitogen-activated protein kinase kinase kinase 7 Polyubiquitin-B Polyubiquitin-C TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 TNF receptor-associated factor 6 TRAF-interacting protein with FHA domain-containing protein A Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O43318 P0CG47 P0CG48 P62979 P62987 Q15750 Q8N5C8 Q96CG3 Q96QP1 Q9NYJ8 Q9Y4K3	ALPK1 KIAA0733 KIAA1527 LAK MAP3K7 MAP3K7IP1 MAP3K7IP2 MAP3K7IP3 RNF85 RPS27A T2BP TAB1 TAB2 TAB3 TAK1 TIFA TRAF6 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Homo sapiens (human)
Defective SLC2A2 causes Fanconi-Bickel syndrome (FBS)	Solute carrier family 2, facilitated glucose transporter member 2	P11168	GLUT2 SLC2A2	Homo sapiens (human)	G58161NS G93924TT
Loss of Nlp from mitotic centrosomes	14-3-3 protein epsilon 14-3-3 protein gamma A-kinase anchor protein 9 Alpha-centractin CDK5 regulatory subunit-associated protein 2 CLIP-associating protein 1 Casein kinase I isoform delta Casein kinase I isoform epsilon Centrin-2 Centriolar coiled-coil protein of 110 kDa Centriole and centriolar satellite protein OFD1 Centriolin Centromere protein J Centrosomal protein 43 Centrosomal protein of 131 kDa Centrosomal protein of 135 kDa Centrosomal protein of 152 kDa Centrosomal protein of 164 kDa Centrosomal protein of 192 kDa Centrosomal protein of 290 kDa Centrosomal protein of 41 kDa Centrosomal protein of 57 kDa Centrosomal protein of 63 kDa Centrosomal protein of 70 kDa Centrosomal protein of 72 kDa Centrosomal protein of 76 kDa Centrosomal protein of 78 kDa Centrosome-associated protein ALMS1 Centrosome-associated protein CEP250 Cyclin-dependent kinase 1 Cytoplasmic dynein 1 heavy chain 1 Cytoplasmic dynein 1 intermediate chain 2 Cytoskeleton-associated protein 5 Dynactin subunit 2 Dynactin subunit 3 Dynein light chain 1, cytoplasmic HAUS augmin-like complex subunit 1 HAUS augmin-like complex subunit 2 HAUS augmin-like complex subunit 3 HAUS augmin-like complex subunit 4 HAUS augmin-like complex subunit 5 HAUS augmin-like complex subunit 6 HAUS augmin-like complex subunit 7 HAUS augmin-like complex subunit 8 Heat shock protein HSP 90-alpha Microtubule nucleation factor SSNA1 Microtubule-associated protein RP/EB family member 1 Ninein-like protein Nuclear distribution protein nudE homolog 1 Outer dense fiber protein 2 Pericentrin Pericentriolar material 1 protein Platelet-activating factor acetylhydrolase IB subunit beta Protein NEDD1 Protein SFI1 homolog Serine/threonine-protein kinase Nek2 Serine/threonine-protein kinase PLK1 Serine/threonine-protein kinase PLK4 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serologically defined colon cancer antigen 8 Tubulin alpha-1A chain Tubulin alpha-4A chain Tubulin beta chain Tubulin beta-4A chain Tubulin beta-4B chain Tubulin gamma-1 chain cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase type II-beta regulatory subunit	A8K8P3 O00444 O15078 O43303 O43805 O75665 O75935 O94927 O94986 O95613 O95684 P04350 P06493 P07437 P07900 P17612 P23258 P30153 P31323 P41208 P43034 P48730 P49674 P51955 P53350 P61163 P61981 P62258 P63167 P68366 P68371 Q13409 Q13561 Q14008 Q14204 Q15154 Q15691 Q5BJF6 Q5JTW2 Q66GS9 Q68CZ6 Q71U36 Q7Z460 Q7Z4H7 Q7Z7A1 Q86SQ7 Q86XR8 Q8NHQ1 Q8NHV4 Q8TAP6 Q8TCU4 Q8TEP8 Q96CS2 Q96MT8 Q96SN8 Q99871 Q99996 Q9BT25 Q9BV73 Q9BYV8 Q9H6D7 Q9HC77 Q9NVX0 Q9NXR1 Q9P209 Q9UPN4 Q9UPV0 Q9Y2I6	ACTR1A AKAP350 AKAP450 AKAP9 ALMS1 AZI1 BBS14 BITE C14orf94 C15orf25 C18orf9 C4orf15 C9orf81 CALT CCCAP CCDC5 CCP110 CDC2 CDC28A CDK1 CDK5RAP2 CDKN1 CEN2 CENPJ CEP1 CEP110 CEP131 CEP135 CEP152 CEP164 CEP192 CEP2 CEP215 CEP250 CEP27 CEP290 CEP4 CEP41 CEP43 CEP57 CEP63 CEP70 CEP72 CEP76 CEP78 CETN2 CKAP5 CLASP1 CNAP1 CNTRL CP110 CPAP CSNK1D CSNK1E CTRN1 CXorf5 DCTN2 DCTN22 DCTN3 DCTN50 DGT6 DHC1 DLC1 DNCH1 DNCI2 DNCIC2 DNCL DNCL1 DNCLC1 DNECL DYHC DYNC1H1 DYNC1I2 DYNLL1 FAM29A FGFR1OP FOP HAUS1 HAUS2 HAUS3 HAUS4 HAUS5 HAUS6 HAUS7 HAUS8 HCKID HDLC1 HEIC HICE1 HSP90A HSP90AA1 HSPC1 HSPCA KIAA0092 KIAA0097 KIAA0325 KIAA0328 KIAA0373 KIAA0402 KIAA0419 KIAA0542 KIAA0622 KIAA0635 KIAA0803 KIAA0841 KIAA0912 KIAA0980 KIAA1052 KIAA1118 KIAA1519 KIAA1569 KIAA1574 KIAA1633 LAP LIP1 LIS1 MAPRE1 MAST1 MDCR MDS NA14 NDE1 NEDD1 NEK2 NEK2A NINL NLK1 NLP NPHP10 NPHP15 NPHP6 NUDE ODF2 OFD1 P34CDC2 PAFAH1B1 PAFAHA PCM1 PCNT PCNT2 PKACA PLK PLK1 PLK4 PPP2R1A PRKACA PRKAR2B SAK SDCCAG8 SFI1 SSNA1 STK18 TSGA14 TSP57 TUBA1 TUBA1A TUBA3 TUBA4A TUBB TUBB2C TUBB4 TUBB4A TUBB4B TUBB5 TUBG TUBG1 UCHL5IP UIP1 YWHAE YWHAG	Homo sapiens (human)
Resistance of ERBB2 KD mutants to afatinib	Erbin Heat shock protein HSP 90-alpha Hsp90 co-chaperone Cdc37 Receptor tyrosine-protein kinase erbB-2	P04626 P07900 Q16543 Q96RT1	CDC37 CDC37A ERBB2 ERBB2IP ERBIN HER2 HSP90A HSP90AA1 HSPC1 HSPCA KIAA1225 LAP2 MLN19 NEU NGL	Homo sapiens (human)
Catecholamine biosynthesis	Aromatic-L-amino-acid decarboxylase Dopamine beta-hydroxylase Phenylethanolamine N-methyltransferase Tyrosine 3-monooxygenase	P07101 P09172 P11086 P20711	AADC DBH DDC PENT PNMT TH TYH	Homo sapiens (human)
Specification of the neural plate border	Bone morphogenetic protein 4 Catenin beta-1 Fibroblast growth factor 4 Homeobox protein DLX-5 Homeobox protein GBX-2 Homeobox protein MSX-1 POU domain, class 5, transcription factor 1 Paired box protein Pax-3 Paired box protein Pax-7 Protein Wnt-3a Transcription factor 7-like 1 Transcription factor AP-2 gamma Transcription factor AP-2-alpha Transcription factor AP-2-beta Transcription factor SOX-2 Transcriptional activator Myb Zinc finger protein ZIC 1	P05549 P08620 P10242 P12644 P23759 P23760 P28360 P35222 P48431 P52951 P56178 P56704 Q01860 Q15915 Q92481 Q92754 Q9HCS4	AP2TF BMP2B BMP4 CTNNB CTNNB1 DLX5 DVR4 FGF4 GBX2 HOX7 HST HSTF1 HUP1 HUP2 KS3 MSX1 MYB OCT3 OCT4 OTF3 PAX3 PAX7 POU5F1 SOX2 TCF3 TCF7L1 TFAP2 TFAP2A TFAP2B TFAP2C WNT3A ZIC ZIC1 ZNF201	Homo sapiens (human)
Myogenesis	BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 C-Jun-amino-terminal kinase-interacting protein 4 Cadherin-15 Cadherin-2 Cadherin-4 Catenin alpha-1 Catenin alpha-2 Catenin beta-1 Cell adhesion molecule-related/down-regulated by oncogenes Cell division control protein 42 homolog Dual specificity mitogen-activated protein kinase kinase 6 Mitogen-activated protein kinase 11 Mitogen-activated protein kinase 12 Mitogen-activated protein kinase 14 Myoblast determination protein 1 Myocyte-specific enhancer factor 2A Myocyte-specific enhancer factor 2B Myocyte-specific enhancer factor 2C Myocyte-specific enhancer factor 2D Myogenic factor 5 Myogenic factor 6 Myogenin Neogenin Netrin-3 Transcription factor 12 Transcription factor 4 Transcription factor E2-alpha Tyrosine-protein kinase ABL1	O00634 O60271 P00519 P13349 P15172 P15173 P15884 P15923 P19022 P23409 P26232 P35221 P35222 P52564 P53778 P55283 P55291 P60953 Q02078 Q02080 Q06413 Q12982 Q14814 Q15759 Q16539 Q4KMG0 Q92859 Q99081	ABL ABL1 BHLHB19 BHLHB20 BHLHB21 BHLHC1 BHLHC2 BHLHC3 BHLHC4 BNIP2 CAPR CDC42 CDH14 CDH15 CDH2 CDH3 CDH4 CDHN CDO CDON CSBP CSBP1 CSBP2 CSPB1 CTNNA1 CTNNA2 CTNNB CTNNB1 E2A ERK6 HEB HSS HTF4 IGDCC2 ITF1 ITF2 JTK7 KIAA0516 MAP2K6 MAPK11 MAPK12 MAPK14 MAPK8IP4 MEF2 MEF2A MEF2B MEF2C MEF2D MEK6 MKK6 MRF4 MXI2 MYF3 MYF4 MYF5 MYF6 MYOD MYOD1 MYOG NCAD NEO1 NGN NIP2 NTN2L NTN3 PRKM11 PRKMK6 SAPK2 SAPK2A SAPK2B SAPK3 SEF2 SKK3 SPAG9 SYD1 TCF12 TCF3 TCF4 XMEF2	Homo sapiens (human)
Signaling by FGFR2 fusions	Fibroblast growth factor receptor 2	P21802	BEK FGFR2 KGFR KSAM	Homo sapiens (human)
MPS IIID - Sanfilippo syndrome D	N-acetylglucosamine-6-sulfatase	P15586	GNS	Homo sapiens (human)	G80016QC
Enzymatic degradation of Dopamine by monoamine oxidase	Amine oxidase [flavin-containing] A Catechol O-methyltransferase	P21397 P21964	COMT MAOA	Homo sapiens (human)
Transcription of the HIV genome	CDK-activating kinase assembly factor MAT1 Cyclin-H Cyclin-dependent kinase 7 DNA-directed RNA polymerase II subunit RPB11-a DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 General transcription and DNA repair factor IIH helicase subunit XPD General transcription and DNA repair factor IIH helicase/translocase subunit XPB General transcription factor IIE subunit 1 General transcription factor IIF subunit 1 General transcription factor IIF subunit 2 General transcription factor IIH subunit 1 General transcription factor IIH subunit 2 General transcription factor IIH subunit 3 General transcription factor IIH subunit 4 General transcription factor IIH subunit 5 TATA-binding protein-associated factor 2N TATA-box-binding protein Transcription initiation factor IIA subunit 1 Transcription initiation factor IIA subunit 2 Transcription initiation factor IIB Transcription initiation factor IIE subunit beta Transcription initiation factor TFIID subunit 1-like Transcription initiation factor TFIID subunit 10 Transcription initiation factor TFIID subunit 11 Transcription initiation factor TFIID subunit 12 Transcription initiation factor TFIID subunit 13 Transcription initiation factor TFIID subunit 1 Transcription initiation factor TFIID subunit 2 Transcription initiation factor TFIID subunit 3 Transcription initiation factor TFIID subunit 4 Transcription initiation factor TFIID subunit 4B Transcription initiation factor TFIID subunit 5 Transcription initiation factor TFIID subunit 6 Transcription initiation factor TFIID subunit 7-like Transcription initiation factor TFIID subunit 7 Transcription initiation factor TFIID subunit 9 Transcription initiation factor TFIID subunit 9B	O00268 O15514 P13984 P18074 P19387 P19388 P19447 P20226 P21675 P24928 P29083 P29084 P30876 P32780 P35269 P36954 P49848 P50613 P51946 P51948 P52434 P52435 P52655 P52657 P53803 P61218 P62487 P62875 Q00403 Q12962 Q13888 Q13889 Q15542 Q15543 Q15544 Q15545 Q16514 Q16594 Q5H9L4 Q5VWG9 Q6P1X5 Q6ZYL4 Q8IZX4 Q92750 Q92759 Q92804 Q9HBM6	BA2R BTF2 BTF2P44 C6orf175 CAK CAK1 CAP35 CCG1 CCGS CCNH CDK7 CDKN7 CIF150 ERCC2 ERCC3 GTF2A1 GTF2A2 GTF2B GTF2D1 GTF2E1 GTF2E2 GTF2F1 GTF2F2 GTF2H1 GTF2H2 GTF2H3 GTF2H4 GTF2H5 MAT1 MNAT1 MO15 POLR2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J1 POLR2K POLR2L POLRF RAP30 RAP74 RBP56 RNF66 RPB7 STK1 TAF1 TAF10 TAF11 TAF12 TAF13 TAF15 TAF1L TAF2 TAF2A TAF2B TAF2C TAF2C1 TAF2C2 TAF2D TAF2E TAF2F TAF2G TAF2H TAF2I TAF2J TAF2K TAF2N TAF2Q TAF3 TAF4 TAF4A TAF4B TAF5 TAF6 TAF7 TAF7L TAF9 TAF9B TAF9L TAFII105 TAFII130 TAFII135 TAFII18 TAFII20 TAFII30 TAFII31 TAFII55 TAFII70 TBP TF2A1 TF2A2 TF2B TF2D TF2E1 TF2E2 TFIIB TFIID TTDA XPB XPBC XPD XPDC	Homo sapiens (human)
DNA Damage/Telomere Stress Induced Senescence	Adrenocortical dysplasia protein homolog Cellular tumor antigen p53 Cyclin-A1 Cyclin-A2 Cyclin-dependent kinase 2 Cyclin-dependent kinase inhibitor 1 Cyclin-dependent kinase inhibitor 1B DNA repair protein RAD50 Double-strand break repair protein MRE11 E1A-binding protein p400 G1/S-specific cyclin-E1 G1/S-specific cyclin-E2 Histone H2A type 1-B/E Histone H2A type 1-C Histone H2A type 1-D Histone H2A type 1-J Histone H2A type 2-A Histone H2A type 2-C Histone H2A-Bbd type 1 Histone H2A.J Histone H2A.V Histone H2AX Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/F/G/I Histone H2B type 1-D Histone H2B type 1-H Histone H2B type 1-J Histone H2B type 1-K Histone H2B type 1-L Histone H2B type 1-M Histone H2B type 1-N Histone H2B type 1-O Histone H2B type 2-E Histone H2B type 3-B Histone H2B type F-S Histone H3.1t Histone H4 Histone acetyltransferase KAT5 Nibrin Protection of telomeres protein 1 Serine-protein kinase ATM TERF1-interacting nuclear factor 2 Telomeric repeat-binding factor 1 Telomeric repeat-binding factor 2-interacting protein 1 Telomeric repeat-binding factor 2	O60814 O60934 O96020 P04637 P04908 P06899 P0C5Y9 P16104 P20248 P20671 P23527 P24864 P24941 P33778 P38936 P46527 P49959 P54274 P57053 P58876 P62805 P62807 P78396 Q13315 Q15554 Q16695 Q16777 Q16778 Q6FI13 Q71UI9 Q8N257 Q92878 Q92993 Q93077 Q93079 Q96A08 Q96AP0 Q96L91 Q99877 Q99878 Q99879 Q99880 Q9BSI4 Q9BTM1 Q9NUX5 Q9NYB0	ACD ATM CAGH32 CAP20 CCN1 CCNA CCNA1 CCNA2 CCNE CCNE1 CCNE2 CDK2 CDKN1 CDKN1A CDKN1B CDKN2 CIP1 DRIP5 EP400 H2AB1 H2AC14 H2AC18 H2AC19 H2AC20 H2AC4 H2AC6 H2AC7 H2AC8 H2AFA H2AFB1 H2AFE H2AFG H2AFJ H2AFL H2AFM H2AFO H2AFQ H2AFV H2AFX H2AJ H2AV H2AX H2AZ2 H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H2BFA H2BFB H2BFC H2BFD H2BFE H2BFF H2BFG H2BFH H2BFJ H2BFK H2BFL H2BFN H2BFQ H2BFR H2BFS H2BFT H2BS1 H2BU1 H3-4 H3FT H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HIRIP1 HIRIP2 HIST1H2AB HIST1H2AC HIST1H2AD HIST1H2AE HIST1H2AJ HIST1H2BA HIST1H2BB HIST1H2BC HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2BI HIST1H2BJ HIST1H2BK HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H2AA HIST2H2AA3 HIST2H2AA4 HIST2H2AC HIST2H2BE HIST2H4 HIST2H4A HIST2H4B HIST3H2BB HIST3H3 HIST4H4 HNGS1 HTATIP KAT5 KIAA1498 KIAA1818 KIP1 MDA6 MRE11 MRE11A NBN NBS NBS1 P53 P95 PIC1 PIN2 PIP1 POT1 PTOP RAD50 RAP1 SDI1 TERF1 TERF2 TERF2IP TIN2 TINF2 TINT1 TIP60 TNRC12 TP53 TPP1 TRBF1 TRBF2 TRF TRF1 TRF2 TSH2B WAF1 p27	Homo sapiens (human)
STAT5 activation downstream of FLT3 ITD mutants	Bcl-2-like protein 1 Cyclin-dependent kinase inhibitor 1 GRB2-associated-binding protein 2 Growth factor receptor-bound protein 2 NADPH oxidase 4 Receptor-type tyrosine-protein kinase FLT3 Serine/threonine-protein kinase pim-1 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Tyrosine-protein phosphatase non-receptor type 11	P11309 P36888 P38936 P42229 P51692 P62993 Q06124 Q07817 Q9NPH5 Q9UQC2	ASH BCL2L BCL2L1 BCLX CAP20 CD135 CDKN1 CDKN1A CIP1 FLK2 FLT3 GAB2 GRB2 KIAA0571 MDA6 NOX4 PIC1 PIM1 PTP2C PTPN11 RENOX SDI1 SHPTP2 STAT5 STAT5A STAT5B STK1 WAF1	Homo sapiens (human)
Defective B4GALT1 causes B4GALT1-CDG (CDG-2d)	Aggrecan core protein Beta-1,4-galactosyltransferase 1 Fibromodulin Keratocan Lumican Mimecan Osteomodulin Prolargin	O60938 P15291 P16112 P20774 P51884 P51888 Q06828 Q99983	ACAN AGC1 B4GALT1 CSPG1 FM FMOD GGTB2 KERA LDC LUM MSK16 OGN OIF OMD PRELP SLRR2A SLRR2B SLRR2C SLRR2D SLRR2E SLRR3A	Homo sapiens (human)
pexidartinib-resistant FLT3 mutants	Receptor-type tyrosine-protein kinase FLT3	P36888	CD135 FLK2 FLT3 STK1	Homo sapiens (human)
Synthesis of Leukotrienes (LT) and Eoxins (EX)	Arachidonate 5-lipoxygenase-activating protein Cytochrome P450 4A11 Cytochrome P450 4A22 Cytochrome P450 4B1 Cytochrome P450 4F11 Cytochrome P450 4F2 Cytochrome P450 4F3 Cytochrome P450 4F8 Dipeptidase 1 Dipeptidase 2 Dipeptidase 3 Glutathione hydrolase 1 proenzyme Glutathione hydrolase 5 proenzyme Leukotriene A-4 hydrolase Leukotriene C4 synthase MAP kinase-activated protein kinase 2 Multidrug resistance-associated protein 1 Polyunsaturated fatty acid 5-lipoxygenase Polyunsaturated fatty acid lipoxygenase ALOX15 Prostaglandin reductase 1 Ultra-long-chain fatty acid omega-hydroxylase	P09917 P09960 P13584 P16050 P16444 P19440 P20292 P33527 P36269 P49137 P78329 P98187 Q02928 Q08477 Q14914 Q16873 Q5TCH4 Q6NT55 Q9H4A9 Q9H4B8 Q9HBI6	ABCC1 ALOX15 ALOX5 ALOX5AP CYP4A11 CYP4A2 CYP4A22 CYP4B1 CYP4F11 CYP4F2 CYP4F22 CYP4F3 CYP4F8 DPEP1 DPEP2 DPEP3 FLAP GGT GGT1 GGT5 GGTLA1 LOG15 LOG5 LTA4 LTA4H LTB4DH LTB4H LTC4S MAPKAPK2 MDP MRP MRP1 PTGR1 RDP	Homo sapiens (human)
SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes	Apoptotic protease-activating factor 1 Caspase-3 Caspase-7 Caspase-9 Cytochrome c Diablo IAP-binding mitochondrial protein E3 ubiquitin-protein ligase XIAP	O14727 P42574 P55210 P55211 P98170 P99999 Q9NR28	APAF1 API3 BIRC4 CASP3 CASP7 CASP9 CPP32 CYC CYCS DIABLO IAP3 KIAA0413 MCH3 MCH6 SMAC XIAP	Homo sapiens (human)
Synthesis of 5-eicosatetraenoic acids	Arachidonate 5-lipoxygenase-activating protein Glutathione peroxidase 1 Glutathione peroxidase 2 Leukotriene C4 synthase Phospholipid hydroperoxide glutathione peroxidase GPX4 Polyunsaturated fatty acid 5-lipoxygenase Serum paraoxonase/arylesterase 1 Serum paraoxonase/arylesterase 2 Serum paraoxonase/lactonase 3	P07203 P09917 P18283 P20292 P27169 P36969 Q15165 Q15166 Q16873	ALOX5 ALOX5AP FLAP GPX1 GPX2 GPX4 LOG5 LTC4S PON PON1 PON2 PON3	Homo sapiens (human)
DAG and IP3 signaling	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Inositol 1,4,5-trisphosphate receptor type 2 Inositol 1,4,5-trisphosphate receptor type 3 Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1 Protein kinase C delta type Protein kinase C epsilon type S-adenosylhomocysteine hydrolase-like protein 1	O43865 P19174 Q02156 Q05655 Q14571 Q14573 Q14643	AHCYL1 DCAL INSP3R1 IRBIT ITPR1 ITPR2 ITPR3 PKCD PKCE PLC1 PLCG1 PRKCD PRKCE XPVKONA	Homo sapiens (human)

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