GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **276 - 300** of **1070** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism
Deactivation of the beta-catenin transactivating complex	14-3-3 protein zeta/delta Adenomatous polyposis coli protein Beta-transducin repeat containing E3 ubiquitin protein ligase C-terminal-binding protein 1 Catenin beta-1 Catenin, beta-interacting protein 1 Chromodomain-helicase-DNA-binding protein 8 E3 ubiquitin-protein ligase XIAP Exportin-1 Histone deacetylase 1 Lymphoid enhancer-binding factor 1 Polyubiquitin-B Polyubiquitin-C Protein chibby homolog 1 RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase SRY-box transcription factor 13 SRY-box transcription factor 17 SRY-box transcription factor 2 SRY-box transcription factor 3 SRY-box transcription factor 7 TLE family member 1, transcriptional corepressor TLE family member 2, transcriptional corepressor Transcription factor 7 like 1 Transcription factor 7 like 2 Transcription factor 7 Transcription factor SOX-6 Transcription factor SOX-9 Transcription factor SOX Transducin-like enhancer protein 3 Transducin-like enhancer protein 4 Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein	A0A0G2JTZ2 A0A0G2K109 A0A8I5Y0T5 A0A8I5ZLY3 A0A8I5ZM42 A0A8I5ZQY6 A0A8I5ZT78 A0A8I6A5Y3 A0A8I6A9A2 A0A8I6AT29 A0A8I6G2R1 D3ZTE1 D4A543 D4A8S0 F1LYL9 G3V923 P0CG51 P47196 P47197 P62982 P63102 P70478 Q07141 Q4QQW4 Q63429 Q80U96 Q8K4I6 Q9JIT3 Q9JIX5 Q9QXN1 Q9R0I6 Q9WU82 Q9Z2F5	Akt1 Akt2 Apc Api3 Bars Birc4 Btrc Catnb Cby Cby1 Chd8 Crm1 Ctbp1 Ctbp3 Ctnnb1 Ctnnbip1 Esp2 Esp3 Grg4 Hdac1 LOC100360645 Lef1 Msfs1 Pgea1 Rps27a Sox-6 Sox13 Sox17 Sox2 Sox3 Sox4 Sox6 Sox7 Sox9 Tcf7 Tcf7l1 Tcf7l2 Tle1 Tle2 Tle3 Tle4 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1 Xiap Xpo1 Ywhaz	Rattus norvegicus (Norway rat)
PKA activation	Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Calmodulin-3 adenylate cyclase cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase type I-alpha regulatory subunit cAMP-dependent protein kinase type I-beta regulatory subunit cAMP-dependent protein kinase type II-alpha regulatory subunit cAMP-dependent protein kinase type II-beta regulatory subunit	D4A3N4 F1LQT1 M0R5U4 P09456 P0DP31 P12368 P12369 P21932 P26769 P26770 P27791 P40146 P68182 P81377 Q03343 Q04400	Adcy1 Adcy2 Adcy3 Adcy4 Adcy5 Adcy6 Adcy7 Adcy8 Adcy9 CaMIII Calm3 Cam3 Camc Pkacb Prkaca Prkacb Prkar1a Prkar1b Prkar2a Prkar2b	Rattus norvegicus (Norway rat)
p53-Dependent G1 DNA Damage Response	Cyclin E2 Cyclin-A1 Cyclin-A2 Cyclin-dependent kinase 2 Cyclin-dependent kinase inhibitor 1A Cyclin-dependent kinase inhibitor 1B G1/S-specific cyclin-E1	A0A0G2JVY9 A0A8I5ZZ18 D3ZQ41 O08769 P39949 Q63699 Q6AY13	Ccna1 Ccna2 Ccne Ccne1 Ccne2 Cdk2 Cdkn1a Cdkn1b Cdkn2 p27Kip1	Rattus norvegicus (Norway rat)
Apoptosis induced DNA fragmentation	Caspase-3 DNA fragmentation factor subunit alpha DNA fragmentation factor subunit beta H1.2 linker histone, cluster member High mobility group protein B1 High mobility group protein B1 High mobility group protein B1 High mobility group protein B1 High mobility group protein B2 Histone H1.0 Histone H1.1 Histone H1.4 Histone H1.5 Importin subunit alpha-5 Importin subunit beta-1	A0A0G2K654 A0A0G2K6P4 A0A8I5Y7D7 A0A8I6ANF5 A0A8I6GBU6 D3ZBN0 D4A3K5 P15865 P43278 P52296 P52925 P55213 P63159 P83953 Q99N34	Cad Casp3 Cpp32 Dffa Dffb H1-0 H1-1 H1-4 H1-5 H1f0 H1f2 H1f4 H1f5 HIf5 Hist1h1a Hist1h1b Hmg-1 Hmg1 Hmg2 Hmgb1 Hmgb1-ps33 Hmgb1-ps4 Hmgb1l1 Hmgb1l2 Hmgb1l3 Hmgb1l5 Hmgb2 Kpna1 Kpnb1 LOC108349189 LOC108350839	Rattus norvegicus (Norway rat)
Heme biosynthesis	5-aminolevulinate synthase, erythroid-specific, mitochondrial 5-aminolevulinate synthase, non-specific, mitochondrial 5-aminolevulinate synthase Albumin Amine oxidase Broad substrate specificity ATP-binding cassette transporter ABCG2 Cytochrome c oxidase assembly homolog COX15 Delta-aminolevulinic acid dehydratase Ferrochelatase Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial Porphobilinogen deaminase Protoheme IX farnesyltransferase, mitochondrial Uroporphyrinogen decarboxylase (Fragment) uroporphyrinogen-III synthase	A0A8I6GEM4 D3ZVN7 D4A414 F1LVF4 F1LVW9 P02770 P06214 P13195 P19356 P32362 Q3B7D0 Q5XIF2 Q63147 Q80W57	Abcg2 Alad Alas1 Alas2 Alase Alb Bcrp1 Cox10 Cox15 Cpo Cpox Fech Hmbs LOC100911779 Ppox Urod Uros	Rattus norvegicus (Norway rat)
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha	26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Cullin 2 Egl nine homolog 1 (Fragment) Elongin-B Elongin-C Endothelial PAS domain-containing protein 1 Hypoxia-inducible factor 1-alpha Hypoxia-inducible factor 3-alpha LIM domain-containing protein 1 LIM domain-containing protein ajuba Polyubiquitin-B Polyubiquitin-C Prolyl hydroxylase EGLN2 Prolyl hydroxylase EGLN3 Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 12 Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 6 Proteasome 26S subunit, non-ATPase 3 Proteasome 26S subunit, non-ATPase 7 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha type Proteasome subunit beta type-10 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Proteasome subunit beta Ring-box 1 Ubiquitin B-like Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 D2 Ubiquitin-conjugating enzyme E2 D3 Ubiquitin-ribosomal protein eS31 fusion protein WT1 interacting protein von Hippel-Lindau disease tumor suppressor	A0A0G2JSL0 A0A0G2JUC8 A0A0G2KAX0 A0A8I5ZM79 A0A8I5ZNE7 A0A8I6A5Y3 A0A8I6G8I6 B0BN93 B5DEH0 D3ZDK2 F1LMC1 F1LMQ3 F1LMZ8 F1M6I7 F7FGV7 G3V6W6 G3V8G2 O35800 O88761 P0CG51 P17220 P18420 P18421 P18422 P21670 P28064 P28073 P28075 P28077 P34064 P34067 P40112 P40307 P48004 P59722 P60901 P61078 P62193 P62198 P62839 P62870 P62982 P83941 Q4FZT9 Q4KM35 Q4V8E2 Q5U2Z2 Q5XIC6 Q5XIU5 Q62630 Q63347 Q63429 Q63569 Q63570 Q63797 Q63798 Q64259 Q6AYU4 Q9JHS1 Q9JHS2 Q9JHW0 Q9WTV5 Q9Z2X3	Ajuba Cul2 Egln1 Egln2 Egln3 Elob Eloc Epas1 Hif1a Hif2a Hif3a Jub LOC100360645 LOC100360846 LOC100365869 Limd1 Lmp10 Lmp2 Mecl1 Mss1 Psma1 Psma2 Psma3 Psma4 Psma5 Psma6 Psma7 Psma8 Psmb1 Psmb10 Psmb2 Psmb3 Psmb4 Psmb5 Psmb6 Psmb6l Psmb6l1 Psmb7 Psmb8 Psmb9 Psmc1 Psmc2 Psmc3 Psmc4 Psmc5 Psmc6 Psmd1 Psmd10 Psmd11 Psmd12 Psmd13 Psmd14 Psmd2 Psmd3 Psmd5 Psmd6 Psmd7 Psmd8 Psmd9 Psme1 Psme2 Psme4 Psmf1 Rbx1 Ring12 Rps27a Sm20 Sug1 Tbp1 Tbp7 Tceb1 Tceb2 Uba80 Ubb Ubbl1 Ubc Ubc4 Ubcep1 Ubch4 Ubch5b Ubcl1 Ube2d1 Ube2d2 Ube2d3 Vhl Wtip	Rattus norvegicus (Norway rat)
Synthesis of bile acids and bile salts via 27-hydroxycholesterol	25-hydroxycholesterol 7-alpha-hydroxylase (Fragment) 3 beta-hydroxysteroid dehydrogenase type 7 Aldo-keto reductase family 1 member C21 Aldo-keto reductase family 1 member D1 Aldo-keto reductase family 1, member C1 Bile acid receptor Cytochrome P450 7A1 Cytochrome P450 family 8 subfamily B member 1 Nuclear receptor coactivator 2 Nuclear receptor coactivator Prostacyclin synthase Retinoic acid receptor RXR-alpha Sterol 26-hydroxylase, mitochondrial	A0A8I6APA0 G3V8J2 O35048 P17178 P18125 P31210 Q05343 Q3MHS3 Q62735 Q62969 Q63688 Q6AYQ2 Q9WUI9	Akr1c1 Akr1c21 Akr1d1 Bar Cca2 Cyp27 Cyp27a1 Cyp7 Cyp7a1 Cyp7b1 Cyp8 Cyp8b1 Fxr Hsd17b5 Hsd3b7 Ncoa1 Ncoa2 Nr1h4 Nr2b1 Ptgis Rip14 Rxra Tif2	Rattus norvegicus (Norway rat)
SCF-beta-TrCP mediated degradation of Emi1	26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Beta-transducin repeat containing E3 ubiquitin protein ligase Cell division cycle protein 20 homolog Cullin 1 Fizzy and cell division cycle 20 related 1 Polyubiquitin-B Polyubiquitin-C Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 12 Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 6 Proteasome 26S subunit, non-ATPase 3 Proteasome 26S subunit, non-ATPase 7 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha type Proteasome subunit beta type-10 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Proteasome subunit beta S-phase kinase-associated protein 1 Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein	A0A0G2JSL0 A0A0G2KAX0 A0A8I5Y0H0 A0A8I5ZM79 A0A8I5ZNE7 A0A8I6A5Y3 A0A8I6G2R1 B0BN93 B1WCA1 F1LMQ3 F1LMZ8 F1M6I7 F7FGV7 G3V6W6 G3V8G2 O88761 P0CG51 P17220 P18420 P18421 P18422 P21670 P28064 P28073 P28075 P28077 P34064 P34067 P40112 P40307 P48004 P60901 P62193 P62198 P62982 Q4FZT9 Q4KM35 Q4V8E2 Q5XIC6 Q5XIU5 Q62623 Q63347 Q63429 Q63569 Q63570 Q63797 Q63798 Q6PEC4 Q9JHW0 Q9WTV5 Q9Z2X3	Btrc Cdc20 Cul1 Fzr1 LOC100360645 LOC100360846 LOC100365869 Lmp10 Lmp2 Mecl1 Mss1 Psma1 Psma2 Psma3 Psma4 Psma5 Psma6 Psma7 Psma8 Psmb1 Psmb10 Psmb2 Psmb3 Psmb4 Psmb5 Psmb6 Psmb6l Psmb6l1 Psmb7 Psmb8 Psmb9 Psmc1 Psmc2 Psmc3 Psmc4 Psmc5 Psmc6 Psmd1 Psmd10 Psmd11 Psmd12 Psmd13 Psmd14 Psmd2 Psmd3 Psmd5 Psmd6 Psmd7 Psmd8 Psmd9 Psme1 Psme2 Psme4 Psmf1 Ring12 Rps27a Skp1 Skp1a Sug1 Tbp1 Tbp7 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1	Rattus norvegicus (Norway rat)
Transport and synthesis of PAPS	3'-phosphoadenosine 5'-phosphosulfate synthase 1 3'-phosphoadenosine 5'-phosphosulfate synthase 2 Adenosine 3'-phospho 5'-phosphosulfate transporter 1 Adenosine 3'-phospho 5'-phosphosulfate transporter 2 Sulfate anion transporter 1 Sulfate transporter	A0A0G2K0L0 A0A0G2K950 D4AAG3 F7FLA1 O70531 P45380	Dtdst Papss1 Papss2 Sat1 Slc26a1 Slc26a2 Slc35b2 Slc35b3	Rattus norvegicus (Norway rat)
Assembly of collagen fibrils and other multimeric structures	Cathepsin B Cathepsin S Collagen alpha-1(I) chain Collagen alpha-1(II) chain Collagen alpha-1(III) chain Collagen alpha-1(V) chain Collagen alpha-1(XI) chain Collagen alpha-2(I) chain Collagen type IV alpha 1 chain Collagen type IV alpha 2 chain Collagen type IV alpha 3 chain Collagen type IV alpha 4 chain Collagen type IV alpha 5 chain Collagen type V alpha 2 chain Collagen type V alpha 3 chain Collagen type VIII alpha 1 chain Collagen type VIII alpha 2 chain Collagen type X alpha 1 chain Collagen type XI alpha 2 chain Collagen type XV alpha 1 chain Collagen type XVIII alpha 1 chain Collagenase 3 (Fragment) Matrilysin Matrix metallopeptidase 20 Matrix metalloproteinase-9 Procathepsin L Similar to Cathepsin L precursor (Major excreted protein) (MEP) Stromelysin-1	A0A0G2JV12 A0A0G2K069 A0A0G2K742 A0A0G2K7A5 A0A8I5ZZ86 A0A8I6GLR1 D3ZKC3 D3ZXD9 D4AC70 D4ADG9 F1LQ00 F1LRJ1 F1M6Q3 F1MA59 F7EVZ0 P00787 P02454 P02466 P03957 P05539 P07154 P13941 P20909 P23097 P50280 P50282 Q02765 Q9JI03	Col10a1 Col11a1 Col11a2 Col15a1 Col18a1 Col1a1 Col1a2 Col2a1 Col3a1 Col4a1 Col4a2 Col4a3 Col4a4 Col4a5 Col5a1 Col5a2 Col5a3 Col8a1 Col8a2 Cts7l2 Ctsb Ctsl Ctsl1 Ctsll3 Ctss LOC100909752 LOC100911572 Mmp-7 Mmp13 Mmp20 Mmp3 Mmp7 Mmp9 RGD1308751	Rattus norvegicus (Norway rat)
RMTs methylate histone arginines	AT-rich interaction domain 1A AT-rich interaction domain 1B Actin-like 6A Actin-like protein 6B Coordinator of PRMT5 and differentiation stimulator Cyclin-dependent kinase 4 DNA (cytosine-5)-methyltransferase 3A G1/S-specific cyclin-D1 Histone H2A type 2-A Histone H2A type 3 Histone H2A.J Histone H2A Histone H2A Histone H2A Histone H3.1 Histone H3 Histone H4 Histone-arginine methyltransferase CARM1 Histone-binding protein RBBP7 Methylosome protein WDR77 Polybromo 1 Protein arginine N-methyltransferase 1 Protein arginine N-methyltransferase 3 Protein arginine N-methyltransferase 5 Protein arginine N-methyltransferase 7 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 Small ribosomal subunit protein uS5 Small ribosomal subunit protein uS5 Transcription activator BRG1 WD repeat-containing protein 5	A0A0G2JVD3 A0A8I5ZMW9 A0A8I5ZQQ2 A0A8I5ZYY0 A0A8I6A5E1 A0A8I6AJE2 A0A8I6AMA8 A0A8I6AWT3 A0A8J8YH81 A9UMV8 D3ZB92 D3ZBS9 D3ZJ08 D3ZT78 D3ZVK7 D4A0E8 E9PTG1 O54772 O70467 P0CC09 P27952 P35426 P39948 P62804 P86173 Q1LZ53 Q498M4 Q4AE70 Q4FZT6 Q4KM87 Q4QR85 Q56A18 Q5U4E8 Q63009 Q6LED0 Q71UF4 Q8K1P7	AABR07029195.1 Actl6a Actl6b Arid1a Arid1b Baf190a Baf57 Baf60b Brg1 Carm1 Ccnd1 Cdk4 Coprs Dnmt3a ENSRNOG00000062927 H2ac10 H2ac18 H2ac25 H2ac4 H2aj H3c13 H4c16 H4c2 H4f16 H4ft Hist1h4b Hist1h4m Hist2h2aa3 Hist2h3c2 Hist3h2a Hist4 Hist4h4 Hrmt1l2 Hrmt1l3 LOC120097726 Mep50 Pbrm1 Prmt1 Prmt3 Prmt4 Prmt5 Prmt7 RGD1565675 Rbbp7 Rps2 Smarca2 Smarca4 Smarcb1 Smarcc1 Smarcc2 Smarcd1 Smarcd2 Smarcd3 Smarce1 Snf2b Snf2l4 Wdr5 Wdr77	Rattus norvegicus (Norway rat)
APC/C:Cdc20 mediated degradation of Securin	26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Anaphase promoting complex subunit 1 Anaphase promoting complex subunit 7 Anaphase-promoting complex subunit 15 Anaphase-promoting complex subunit 16 Anaphase-promoting complex subunit 2 Anaphase-promoting complex subunit 4 Anaphase-promoting complex subunit 5 Anaphase-promoting complex subunit CDC26 Cell division cycle 16 Cell division cycle 23 Cell division cycle protein 20 homolog Cell division cycle protein 27 homolog E2 ubiquitin-conjugating enzyme Polyubiquitin-B Polyubiquitin-C Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 12 Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 6 Proteasome 26S subunit, non-ATPase 3 Proteasome 26S subunit, non-ATPase 7 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha type Proteasome subunit beta type-10 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Proteasome subunit beta Securin Ubiquitin B-like Ubiquitin-conjugating enzyme E2 C Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 S Ubiquitin-ribosomal protein eS31 fusion protein	A0A0G2JSL0 A0A0G2KAX0 A0A8I5ZM79 A0A8I5ZNE7 A0A8I6A4J8 A0A8I6A5Y3 A0A8I6AE10 A0A8I6ANL9 A1L1K3 B0BN93 B5DFI8 D3ZDK2 D3ZDN9 D3ZIT4 D3ZQX4 D3ZUB7 D3ZUW6 F1LMQ3 F1LMZ8 F1M3L4 F1M6I7 F7EWF8 F7FGV7 G3V6W6 G3V8G2 O88761 P0CG51 P17220 P18420 P18421 P18422 P21670 P28064 P28073 P28075 P28077 P34064 P34067 P40112 P40307 P48004 P60901 P62193 P62198 P62982 P97613 Q4FZT9 Q4KM35 Q4V8A2 Q4V8E2 Q5XIC6 Q5XIU5 Q62623 Q63347 Q63429 Q63569 Q63570 Q63797 Q63798 Q6YDN7 Q9JHW0 Q9WTV5 Q9Z2X3	Anapc1 Anapc15 Anapc16 Anapc2 Anapc4 Anapc5 Anapc7 Cdc16 Cdc20 Cdc23 Cdc26 Cdc27 LOC100360645 LOC100360846 LOC100365869 LOC100366017 Lmp10 Lmp2 Mecl1 Mss1 Psma1 Psma2 Psma3 Psma4 Psma5 Psma6 Psma7 Psma8 Psmb1 Psmb10 Psmb2 Psmb3 Psmb4 Psmb5 Psmb6 Psmb6l Psmb6l1 Psmb7 Psmb8 Psmb9 Psmc1 Psmc2 Psmc3 Psmc4 Psmc5 Psmc6 Psmd1 Psmd10 Psmd11 Psmd12 Psmd13 Psmd14 Psmd2 Psmd3 Psmd5 Psmd6 Psmd7 Psmd8 Psmd9 Psme1 Psme2 Psme4 Psmf1 Pttg Pttg1 Ring12 Rps27a Sug1 Tbp1 Tbp7 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1 Ube2c Ube2d1 Ube2e1 Ube2s	Rattus norvegicus (Norway rat)
TRIF-mediated programmed cell death	Caspase-8 FAS-associated death domain protein Lymphocyte antigen 96 Monocyte differentiation antigen CD14 Receptor interacting serine/threonine kinase 1 Receptor-interacting serine/threonine-protein kinase 3 TIR domain containing adaptor molecule 2 TIR domain-containing adapter molecule 1 Toll-like receptor 4	D3ZXR7 D3ZYL0 M0RA08 Q56DL5 Q63691 Q8R2E7 Q9JHX4 Q9QX05 Q9Z2P5	Casp8 Cd14 Fadd Ly96 Plin3 Rip3 Ripk1 Ripk3 Ticam1 Ticam2 Tlr4	Rattus norvegicus (Norway rat)
Regulation of IFNA/IFNB signaling	Interferon 1ai1 Interferon 1ai2 Interferon 1ai3 Interferon alpha and beta receptor subunit 1 Interferon alpha and beta receptor subunit 2 Interferon alpha-1-like Interferon alpha-12-like Interferon alpha-12-like Interferon alpha-12-like Interferon alpha-12-like Interferon alpha-12-like Interferon alpha-1 Interferon beta Signal transducer and activator of transcription 4 Signal transducer and activator of transcription Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type 11 Tyrosine-protein phosphatase non-receptor type 1 Tyrosine-protein phosphatase non-receptor type 6 Uncharacterized protein ubiquitinyl hydrolase 1	A0A0G2JX93 A0A7R8C3L7 A0A8I5ZN08 A0A8I5ZQR5 A0A8I6A4N8 A0A8I6AEQ7 A0A8I6AM23 A0A8I6AN84 A0A8I6ANZ6 A0A8I6GMD9 D3Z919 D3ZD03 D3ZDS9 D3ZFH0 F7EYG9 M0R8H7 P05011 P20417 P41499 P70499 P81718 Q6AYC7	ENSRNOG00000065554 If1ai1 If1ai2 If1ai3 Ifna1 Ifna12l Ifna4 Ifna4l1 Ifnar1 Ifnar2 Ifnb Ifnb1 Jak1 LOC100911527 LOC120103158 LOC120103159 LOC120103160 LOC120103161 LOC120103162 LOC120103163 LOC120103164 Ptph6 Ptpn1 Ptpn11 Ptpn6 RGD1560539 Stat1 Stat2 Stat4 Tyk2 Usp18	Rattus norvegicus (Norway rat)
Recycling of bile acids and salts	ATP-binding cassette sub-family C member 3 Albumin Bile acid receptor Bile acid-CoA Bile salt export pump Gastrotropin Hepatic sodium/bile acid cotransporter Ileal sodium/bile acid cotransporter Long-chain fatty acid transport protein 5 Nuclear receptor coactivator 2 Nuclear receptor coactivator Retinoic acid receptor RXR-alpha Solute carrier family 51 subunit alpha Solute carrier family 51 subunit beta Solute carrier organic anion transporter family member 1A4 Solute carrier organic anion transporter family member 1B2 StAR-related lipid transfer domain containing 5	A0A8I6APA0 D3ZN38 D3ZYJ2 D4AC81 O35913 O70127 O88563 P02770 P26435 P80020 Q05343 Q62633 Q62735 Q63276 Q9ES38 Q9QZX8 Q9WUI9	Abcb11 Abcc3 Acsb Alb Baat Bar Bsep Cmoat2 Fabp6 Fatp5 Fxr Ilbp Illbp Mlp2 Mrp3 Ncoa1 Ncoa2 Nr1h4 Nr2b1 Ntcp Ntcp2 Oatp1a4 Oatp1b2 Oatp2 Rip14 Rxra Slc10a1 Slc10a2 Slc21a10 Slc21a5 Slc27a5 Slc51a Slc51b Slco1a4 Slco1b2 Spgp Stard5 Tif2 Vlacsr	Rattus norvegicus (Norway rat)
Post-translational protein phosphorylation	Ac2-248 Albumin Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A Alpha-1-antiproteinase Alpha-2-HS-glycoprotein Alpha-fetoprotein Ameloblastin Amelogenin, X isoform Amelotin Amyloid beta precursor like protein 2 Amyloid-beta precursor protein Anoctamin Apolipoprotein A-I Apolipoprotein A-II Apolipoprotein A-V Apolipoprotein B-100 Apolipoprotein E Apolipoprotein L 11a Apolipoprotein L 9a Apolipoprotein L, 2 Apolipoprotein L3-like BPI fold containing family B, member 2 Bone morphogenetic protein 15 Bone morphogenetic protein 4 CCN family member 1 Cadherin-2 Ceruloplasmin Chordin-like protein 1 Complement C3 Complement C4 Complement C4B (Chido blood group) Cystatin-C Cytoskeleton-associated protein 4 Dentin matrix acidic phosphoprotein 1 Disintegrin and metalloproteinase domain-containing protein 10 DnaJ homolog subfamily C member 3 Enamelin Endoplasmin FAM20A, golgi associated secretory pathway pseudokinase FAM20C, golgi associated secretory pathway kinase Fibrillin 1 Fibrinogen alpha chain Fibrinogen gamma chain Fibroblast growth factor 23 Fibronectin Follistatin-related protein 1 Follistatin-related protein 3 Galectin-1 Glucosidase 2 subunit beta Glypican-3 Golgi membrane protein 1 Growth arrest-specific protein 6 Heparin cofactor 2 Histidine rich calcium binding protein Insulin-like growth factor binding protein 7 Insulin-like growth factor-binding protein 1 Insulin-like growth factor-binding protein 3 Insulin-like growth factor-binding protein 4 Insulin-like growth factor-binding protein 5 Inter-alpha-trypsin inhibitor heavy chain 2 Interleukin-6 Kinectin 1 Kininogen-1 Lactadherin Latent-transforming growth factor beta-binding protein 1 MIA SH3 domain ER export factor 3 Macrophage colony-stimulating factor 1 Matrilin 3 Matrix extracellular phosphoglycoprotein Matrix remodeling-associated protein 8 Melanotransferrin Membrane-bound transcription factor site-1 protease Menin Mesothelin Metalloproteinase inhibitor 1 Multiple epidermal growth factor-like domains protein 6 Neurosecretory protein VGF Nucleobindin-1 Osteopontin Patatin-like phospholipase domain-containing protein 2 Plasma alpha-L-fucosidase Proenkephalin-A Proprotein convertase subtilisin/kexin type 9 Protein Z-dependent protease inhibitor Protein disulfide-isomerase A6 Protein disulfide-isomerase Reticulocalbin 1 SPARC-like protein 1 Secreted phosphoprotein 24 Secretogranin-1 Secretogranin-2 Secretogranin-3 Serine protease 23 Serotransferrin Similar to apolipoprotein L2; apolipoprotein L-II Stanniocalcin-2 Sulfhydryl oxidase 1 Syndecan-2 Tenascin C Trans-Golgi network integral membrane protein TGN38 Transmembrane protein 132A Uncharacterized LOC108351606 Uncharacterized protein Versican core protein (Fragments) Vitamin K-dependent protein C Wolframin ER transmembrane glycoprotein [Wnt protein] O-palmitoleoyl-L-serine hydrolase von Willebrand factor A domain-containing protein 1	A0A0G2JVM2 A0A0G2JXY3 A0A0G2JYF9 A0A0G2K7F8 A0A8I5ZPY1 A0A8I5ZV45 A0A8I5ZVC4 A0A8I6A4W2 A0A8I6AII9 A0A8I6ARC1 A0A8I6G5V5 A0A8I6GCQ3 B1WC34 D3ZH41 D3ZIB0 D3ZUB0 D3ZXI3 D4A5H4 D4ADK7 E9PT53 E9PTU9 F1M512 F1M9B2 G3V8S6 G3V9M6 I7LRF5 M0RBH1 O35314 O88281 P01026 P02650 P02680 P02770 P02773 P04094 P04638 P04639 P04785 P04937 P06399 P08592 P08649 P08721 P08934 P0C548 P10362 P11762 P12346 P13265 P13635 P14841 P15473 P15943 P17475 P19814 P20156 P20607 P21743 P21744 P24054 P24090 P24594 P30120 P31394 P34900 P47868 P59996 P63278 P70490 P98193 Q00918 Q06826 Q10743 Q3HS82 Q5M854 Q5XI43 Q5XIB6 Q62632 Q62740 Q62840 Q62975 Q63081 Q63083 Q63772 Q64268 Q642A6 Q66HD0 Q6AY61 Q6AYS4 Q6IUU3 Q6MG90 Q76LD0 Q7TMA5 Q7TPI9 Q80WF4 Q8JZQ0 Q8VI82 Q99PW7 Q9ERA7 Q9ERB4 Q9ES02 Q9ES72 Q9QUH3 Q9R0K8 Q9R0T3 Q9WTZ3 Q9WVR8 Q9Z1Y3	2b7 A4 AABR07058479.1 AD1 APPL2 Adam10 Afp Ags Ahsg Alb Ambn Amel Amelx Amgx Amtn Ano8 Aplp2 Apoa1 Apoa2 Apoa5 Apob Apoe Apol11a Apol2 Apol7a Apol7b Apol9a App Atgl Bmp-4 Bmp15 Bmp4 Bpifb2 C3 C4 C4a C4b Cabp1 Ccn1 Cdh2 Chgb Chgc Chrdl1 Ckap4 Cp Csf1 Csfm Cspg2 Cst3 Cyr61 Dmp1 Dnajc3 Dvr-4 Egfl3 Enam Erc Fam20a Fam20c Fbn1 Fetua Fga Fgf23 Fgg Flrg Fn1 Frp Fstl1 Fstl3 Fuca2 Gas6 Gbp Golm1 Gpc3 Grp94 Hcf2 Hrc Hsp90b1 Hspa5bp1 Hspc4 Hspg1 Igfbp-1 Igfbp-3 Igfbp-4 Igfbp-5 Igfbp1 Igfbp10 Igfbp3 Igfbp4 Igfbp5 Igfbp7 Il-6 Il6 Itih2 Kjr Kng Kng1 Ktn1 LOC120093819 LOC503164 Lgals1 Ltbp1 Madm Matn3 Mbtps1 Megf6 Meltf Men1 Mepe Mfge8 Mfi2 Mgat4a Mia3 Mpf Msln Mxra8 Narc1 Ng1 Notum Nuc Nucb1 P4hb P58ipk Pcsk9 Pdia1 Pdia6 Penk Penk-rs Penk1 Pnpla2 Prkcsh Proc Prss23 Qscn6 Qsox1 RGD1309808 Rap3 Rasp1 Rcn1 S1p Sc1 Scg-2 Scg2 Scg3 Sdc2 Serpina1 Serpina10 Serpinc1 Serpind1 Ski1 Sox2 Sparcl1 Spp-1 Spp1 Spp2 Spp24 Stc2 Synd2 Tf Timp-1 Timp1 Tmem132a Tnc Tra1 Ttgn1 Txndc7 Vcan Vgf Vwa1 Wfs1 Zpi	Rattus norvegicus (Norway rat)
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest	Cyclin E2 Cyclin-A1 Cyclin-A2 Cyclin-dependent kinase 2 Cyclin-dependent kinase inhibitor 1A Cyclin-dependent kinase inhibitor 1B G1/S-specific cyclin-E1 Transcription factor E2F7 Transcription factor E2F8	A0A0G2JVY9 A0A8I5ZZ18 D3ZQ41 D4A4D7 F1LMN3 O08769 P39949 Q63699 Q6AY13	Ccna1 Ccna2 Ccne Ccne1 Ccne2 Cdk2 Cdkn1a Cdkn1b Cdkn2 E2f7 E2f8 p27Kip1	Rattus norvegicus (Norway rat)
FRS-mediated FGFR1 signaling	Fibroblast growth factor 10 Fibroblast growth factor 17 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor 9 Fibroblast growth factor receptor 1 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor substrate 3 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GTPase HRas GTPase KRas GTPase NRas Growth factor receptor-bound protein 2 Klotho SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein phosphatase non-receptor type 11	A0A8I6B5D5 D4A244 D4A3T0 F1LSQ8 P08644 P13109 P20171 P36364 P41499 P48807 P61149 P62994 P63076 P70492 Q04589 Q04970 Q52RG8 Q8R5L5 Q8R5L9 Q8VI79 Q8VI82 Q9EST9 Q9Z2Y9	Ash FGF22 FGF6 Fgf-1 Fgf-2 Fgf-5 Fgf-9 Fgf1 Fgf10 Fgf17 Fgf2 Fgf20 Fgf22 Fgf23 Fgf3 Fgf4 Fgf5 Fgf5c Fgf5d Fgf6 Fgf7a Fgf7b Fgf8 Fgf9 Fgfa Fgfr1 Flg Frs2 Frs3 Grb2 Hras Hras1 Kl Kras Kras2 Nras Ptpn11 Snt2 Sos1	Rattus norvegicus (Norway rat)
Response to elevated platelet cytosolic Ca2+	Protein kinase C alpha type Protein kinase C beta type Protein kinase C gamma type	P05696 P63319 P68403	Pkca Pkcb Pkcc Pkcg Prkca Prkcb Prkcb1 Prkcc Prkcg	Rattus norvegicus (Norway rat)
Synthesis of IPs in the ER lumen	Multiple inositol polyphosphate phosphatase 1	O35217	Minpp1	Rattus norvegicus (Norway rat)
GAB1 signalosome	Amphiregulin Betacellulin GRB2-associated binding protein 1 Growth factor receptor-bound protein 2 Paxillin Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 Pro-epidermal growth factor Proepiregulin Proheparin-binding EGF-like growth factor Proto-oncogene tyrosine-protein kinase Src Protransforming growth factor alpha Receptor protein-tyrosine kinase Tyrosine-protein kinase CSK Tyrosine-protein phosphatase non-receptor type 11	A0A0G2K344 A0A8I6AQ55 D3ZAL7 G3V6K6 P01134 P07522 P24338 P32577 P41499 P62994 Q06175 Q63787 Q66H76 Q9JM80 Q9WUD9 Q9Z0L5	Areg Ash Btc Cbp Csk Dtr Egf Egfr Ereg Gab1 Grb2 Hbegf Hegfl Pag Pag1 Pik3ca Pik3r1 Ptpn11 Pxn Sdgf Src Tgfa	Rattus norvegicus (Norway rat)
Adrenaline,noradrenaline inhibits insulin secretion	Adenylate cyclase type 5 Adenylate cyclase type 6 Alpha-2A adrenergic receptor Alpha-2C adrenergic receptor Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(i) subunit alpha-1 Guanine nucleotide-binding protein G(i) subunit alpha-2 Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma	A0A8I6AF64 A0A8I6GAY3 A0A8I6GLD4 D4AAI1 F2Z3T8 G3V8K2 O35353 P04897 P10824 P22086 P22909 P43425 P52287 P54311 P54313 P61954 P62882 P63077 P63219 Q03343 Q04400	Adcy5 Adcy6 Adra2a Adra2c Gnai-1 Gnai-2 Gnai1 Gnai2 Gnb1 Gnb2 Gnb3 Gnb4 Gnb5 Gng10-ps1 Gng11 Gng12 Gng3 Gng4 Gng5 Gng5-ps4 Gng7 Gng8 Gng9 Gngt1 Gngt11 Gngt5 Gngt7 Gngt9	Rattus norvegicus (Norway rat)
p130Cas linkage to MAPK signaling for integrins	Adapter molecule crk Amyloid beta A4 precursor protein-binding family B member 1-interacting protein Breast cancer anti-estrogen resistance protein 1 Fibrinogen alpha chain Fibrinogen beta chain Fibrinogen gamma chain Fibronectin Focal adhesion kinase 1 Integrin beta-3 Integrin subunit alpha 2b Proto-oncogene tyrosine-protein kinase Src Ras-related protein Rap-1A Ras-related protein Rap-1b Talin 1	A0A8I6ABG6 A0A8I6GGN2 D3ZDZ1 O35346 P02680 P04937 P06399 P14480 P62836 Q62636 Q63767 Q63768 Q8R2H2 Q9WUD9	Apbb1ip Bcar1 Cas Crk Crkas Crko Fak Fak1 Fga Fgb Fgg Fn1 Itga2b Itgb3 Krev1 Ptk2 Rap1a Rap1b Src Tln1	Rattus norvegicus (Norway rat)
Fibronectin matrix formation	Carcinoembryonic antigen-related cell adhesion molecule 1 Fibronectin Integrin beta-1 Integrin subunit alpha 5	A0A0G2K1E2 P04937 P16573 P49134	Ceacam1 Fn1 Itga5 Itgb1	Rattus norvegicus (Norway rat)
Reduction of cytosolic Ca++ levels	Calmodulin-3 Plasma membrane calcium-transporting ATPase 1 Plasma membrane calcium-transporting ATPase 3 Plasma membrane calcium-transporting ATPase 4 Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 Sodium/calcium exchanger 1 Sodium/calcium exchanger 2 Sodium/calcium exchanger 3 Sorcin	A0A8I5Y9M9 P0DP31 P11505 P11507 P18596 P48768 P70549 Q01728 Q64542 Q64568 Q64578	Atp2a1 Atp2a2 Atp2a3 Atp2b1 Atp2b3 Atp2b4 CaMIII Calm3 Cam3 Camc Ncx1 Ncx2 Ncx3 Pmca3 Slc8a1 Slc8a2 Slc8a3 Sri	Rattus norvegicus (Norway rat)

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