GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **401 - 425** of **1070** in total

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Pathway Name	Protein Name ▼	UniProt ID	Gene Symbol	Organism
Assembly of collagen fibrils and other multimeric structures	Cathepsin B Cathepsin S Collagen alpha-1(I) chain Collagen alpha-1(II) chain Collagen alpha-1(III) chain Collagen alpha-1(V) chain Collagen alpha-1(XI) chain Collagen alpha-2(I) chain Collagen type IV alpha 1 chain Collagen type IV alpha 2 chain Collagen type IV alpha 3 chain Collagen type IV alpha 4 chain Collagen type IV alpha 5 chain Collagen type V alpha 2 chain Collagen type V alpha 3 chain Collagen type VIII alpha 1 chain Collagen type VIII alpha 2 chain Collagen type X alpha 1 chain Collagen type XI alpha 2 chain Collagen type XV alpha 1 chain Collagen type XVIII alpha 1 chain Collagenase 3 (Fragment) Matrilysin Matrix metallopeptidase 20 Matrix metalloproteinase-9 Procathepsin L Similar to Cathepsin L precursor (Major excreted protein) (MEP) Stromelysin-1	A0A0G2JV12 A0A0G2K069 A0A0G2K742 A0A0G2K7A5 A0A8I5ZZ86 A0A8I6GLR1 D3ZKC3 D3ZXD9 D4AC70 D4ADG9 F1LQ00 F1LRJ1 F1M6Q3 F1MA59 F7EVZ0 P00787 P02454 P02466 P03957 P05539 P07154 P13941 P20909 P23097 P50280 P50282 Q02765 Q9JI03	Col10a1 Col11a1 Col11a2 Col15a1 Col18a1 Col1a1 Col1a2 Col2a1 Col3a1 Col4a1 Col4a2 Col4a3 Col4a4 Col4a5 Col5a1 Col5a2 Col5a3 Col8a1 Col8a2 Cts7l2 Ctsb Ctsl Ctsl1 Ctsll3 Ctss LOC100909752 LOC100911572 Mmp-7 Mmp13 Mmp20 Mmp3 Mmp7 Mmp9 RGD1308751	Rattus norvegicus (Norway rat)
RUNX3 regulates WNT signaling	Catenin beta-1 Lymphoid enhancer-binding factor 1 Runt-related transcription factor Transcription factor 7 like 1 Transcription factor 7 like 2 Transcription factor 7	A0A0G2K7T0 A0A8I5ZLY3 A0A8I5ZT78 A0A8I6A9A2 Q9QXN1 Q9WU82	Catnb Ctnnb1 Lef1 Runx3 Tcf7 Tcf7l1 Tcf7l2	Rattus norvegicus (Norway rat)
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production	Catenin beta-1 Histone lysine acetyltransferase CREBBP Interferon regulatory factor 3 histone acetyltransferase	A0A8I6G641 F7EXX5 Q6JHU9 Q9WU82	Catnb Cbp Crebbp Ctnnb1 Ep300 Irf3	Rattus norvegicus (Norway rat)
FasL/ CD95L signaling	Caspase-8 FAS-associated death domain protein Tumor necrosis factor ligand superfamily member 6 Tumor necrosis factor receptor superfamily member 6	P36940 Q63199 Q8R2E7 Q9JHX4	Apt1 Apt1Lg1 Casp8 Cd95l Fadd Fas Fasl Faslg Tnfrsf6 Tnfsf6	Rattus norvegicus (Norway rat)
Ligand-dependent caspase activation	Caspase-8 FAS-associated death domain protein Lymphocyte antigen 96 Monocyte differentiation antigen CD14 Receptor interacting serine/threonine kinase 1 TIR domain containing adaptor molecule 2 TIR domain-containing adapter molecule 1 Toll-like receptor 4	D3ZXR7 D3ZYL0 M0RA08 Q56DL5 Q63691 Q8R2E7 Q9JHX4 Q9QX05	Casp8 Cd14 Fadd Ly96 Plin3 Ripk1 Ticam1 Ticam2 Tlr4	Rattus norvegicus (Norway rat)
TRIF-mediated programmed cell death	Caspase-8 FAS-associated death domain protein Lymphocyte antigen 96 Monocyte differentiation antigen CD14 Receptor interacting serine/threonine kinase 1 Receptor-interacting serine/threonine-protein kinase 3 TIR domain containing adaptor molecule 2 TIR domain-containing adapter molecule 1 Toll-like receptor 4	D3ZXR7 D3ZYL0 M0RA08 Q56DL5 Q63691 Q8R2E7 Q9JHX4 Q9QX05 Q9Z2P5	Casp8 Cd14 Fadd Ly96 Plin3 Rip3 Ripk1 Ripk3 Ticam1 Ticam2 Tlr4	Rattus norvegicus (Norway rat)
Breakdown of the nuclear lamina	Caspase-6 Lamin-B1 Prelamin-A/C	O35397 P48679 P70615	Casp6 Lmn1 Lmna Lmnb1 Mch2	Rattus norvegicus (Norway rat)
Other interleukin signaling	Caspase-3 Interleukin-34 Macrophage colony-stimulating factor 1 receptor Macrophage colony-stimulating factor 1 Pro-interleukin-16 Receptor-type tyrosine-protein phosphatase zeta Synaptosomal-associated protein 25 Syndecan-1 Syntaxin-1A Syntaxin-3 Syntaxin-4 Syntaxin-binding protein 2 T-cell surface glycoprotein CD4 Taxilin alpha Vesicle-associated membrane protein 2	A0A8I6AF93 B2GV14 P05540 P26260 P32851 P55213 P60881 P63045 Q00495 Q08849 Q08850 Q4KM46 Q62656 Q62753 Q8JZQ0	Casp3 Cd4 Cpp32 Csf1 Csf1r Csfm Csfmr Fms IL16 Il16 Il34 Ptprz Ptprz1 Ptpz Sap Sdc1 Snap Snap25 Stx1a Stx3 Stx3a Stx4 Stx4a Stxbp2 Syb2 Synd1 Txlna Unc18b Vamp2	Rattus norvegicus (Norway rat)
Apoptosis induced DNA fragmentation	Caspase-3 DNA fragmentation factor subunit alpha DNA fragmentation factor subunit beta H1.2 linker histone, cluster member High mobility group protein B1 High mobility group protein B1 High mobility group protein B1 High mobility group protein B1 High mobility group protein B2 Histone H1.0 Histone H1.1 Histone H1.4 Histone H1.5 Importin subunit alpha-5 Importin subunit beta-1	A0A0G2K654 A0A0G2K6P4 A0A8I5Y7D7 A0A8I6ANF5 A0A8I6GBU6 D3ZBN0 D4A3K5 P15865 P43278 P52296 P52925 P55213 P63159 P83953 Q99N34	Cad Casp3 Cpp32 Dffa Dffb H1-0 H1-1 H1-4 H1-5 H1f0 H1f2 H1f4 H1f5 HIf5 Hist1h1a Hist1h1b Hmg-1 Hmg1 Hmg2 Hmgb1 Hmgb1-ps33 Hmgb1-ps4 Hmgb1l1 Hmgb1l2 Hmgb1l3 Hmgb1l5 Hmgb2 Kpna1 Kpnb1 LOC108349189 LOC108350839	Rattus norvegicus (Norway rat)
Interleukin-1 processing	Caspase-1 Cathepsin G Gasdermin D Interleukin-1 alpha Interleukin-1 beta Interleukin-18 Nuclear factor kappa B subunit 2 RELA proto-oncogene, NF-kB subunit	A0A096MJ11 A0A8I5ZMV7 A0A8I6G6F3 P16598 P17977 P43527 P97636 Q63264	Casp1 Ctsg Gsdmd Igif Il18 Il1a Il1b Il1bc Il1bce Nfkb2 Rela	Rattus norvegicus (Norway rat)
Formation of the cornified envelope	Caspase 14 Chymotrypsin-like elastase family member 2A Corneodesmosin Desmocollin 1 Desmocollin 2 Desmocollin 3 Desmoglein 1 Desmoglein 2 Desmoglein 3 Desmoglein-4 Desmoplakin Envoplakin Junction plakoglobin Kallikrein k Kallikrein l Kallikrein m Kallikrein related-peptidase 5 Kallikrein-8 Kazrin Lipase Lipase Lipase P53 apoptosis effector related to PMP22 Periplakin Plakophilin 1 Plakophilin 3 Plakophilin 4 Plakophilin-2 Protein-glutamine gamma-glutamyltransferase K Repetin Serine peptidase inhibitor, Kazal type 5 Serine protease inhibitor Kazal-type 6 Small proline-rich protein 3 Stefin A2-like 3	A0A0G2K230 A0A0G2K430 A0A0G2KA90 A0A8I5ZKH8 A0A8I6A880 A0A8I6AG90 A0A8I6GLK6 B2GVC0 D3ZD22 D3ZET2 D3ZHQ6 D3ZJ50 D3ZJ70 D3ZJR7 D3ZL74 D3ZM39 D3ZRA7 D3ZRF0 D3ZY51 D3ZZ65 D4A5T8 D4A9L7 D4AA61 F1LMV6 F1M091 F1M7L9 G3V765 O88780 P00774 P23606 Q5FWS6 Q6IE47 Q6P0K8 Q6W3B0	AABR07044375.1 Bsp1 Casp14 Cdsn Cela2a Dsc1 Dsc2 Dsc3 Dsg1 Dsg2 Dsg3 Dsg4 Dsp Ela2 Ela2a Evpl Jup Kaz Kazn Klk12 Klk13 Klk14 Klk5 Klk8 Klnk Klnl Klnm Lipk Lipm Lipn Nrpn Perp Pg Pkp1 Pkp2 Pkp3 Pkp4 Ppl Prss19 Rptn Spink5 Spink5l1 Spink6 Sprr3 Stfa2l3 Tgm1	Rattus norvegicus (Norway rat)
Signal transduction by L1	Casein kinase II subunit alpha Casein kinase II subunit alpha Casein kinase II subunit beta Dual specificity mitogen-activated protein kinase kinase 1 Dual specificity mitogen-activated protein kinase kinase 2 Fibroblast growth factor receptor 1 Integrin beta-1 Integrin beta-3 Integrin subunit alpha 2b Integrin subunit alpha 5 Integrin subunit alpha 9 Integrin subunit alpha V Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Neural cell adhesion molecule 1 Neural cell adhesion molecule L1 Neuropilin-1 Ras-related C3 botulinum toxin substrate 1 Receptor protein-tyrosine kinase Serine/threonine-protein kinase PAK 1 Vav guanine nucleotide exchange factor 2	A0A0G2K1E2 A0A8I6GGN2 D3ZN51 D3ZYG0 F1LZX9 F7FH41 G3V6K6 P13596 P19139 P21708 P35465 P36506 P49134 P63086 P67874 Q01986 Q04589 Q05695 Q6RUV5 Q8R2H2 Q9QWJ9	Caml1 Ck2n Csnk2a1 Csnk2a2 Csnk2b Egfr Erk1 Erk2 Fgfr1 Flg Itga2b Itga5 Itga9 Itgav Itgb1 Itgb3 L1cam Map2k1 Map2k2 Mapk Mapk1 Mapk3 Mek1 Mek2 Mkk2 Ncam Ncam1 Nrp1 Pak1 Prkm1 Prkm3 Prkmk1 Prkmk2 Rac Rac1 Vav2	Rattus norvegicus (Norway rat)
WNT mediated activation of DVL	Casein kinase II subunit alpha Casein kinase II subunit alpha Casein kinase II subunit beta Dishevelled segment polarity protein 2 Dishevelled segment polarity protein 3 Phosphatidylinositol 4-phosphate 5-kinase type-1 beta Segment polarity protein dishevelled homolog DVL-1 non-specific serine/threonine protein kinase	A0A8I6GKX7 D3ZB71 F7FH41 P19139 P67874 Q5CZZ9 Q99PS2 Q9WVB9	Ck1e-2 Ck2n Csnk1e Csnk2a1 Csnk2a2 Csnk2b Dvl1 Dvl2 Dvl3 LOC100361515 Pip5k1b	Rattus norvegicus (Norway rat)
Condensation of Prometaphase Chromosomes	Casein kinase II subunit alpha Casein kinase II subunit alpha Casein kinase II subunit beta Condensin complex subunit 1 Condensin complex subunit 2 Non-SMC condensin I complex, subunit G Structural maintenance of chromosomes protein Structural maintenance of chromosomes protein	A0A0G2JWH3 A0A8I6GK63 D3ZD72 D4A5Q2 D4A8M7 F7FH41 P19139 P67874	Ck2n Csnk2a1 Csnk2a2 Csnk2b Ncapd2 Ncapg Ncaph Smc2 Smc4	Rattus norvegicus (Norway rat)
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding	Casein kinase II subunit alpha Casein kinase II subunit alpha Casein kinase II subunit beta Chaperonin containing TCP1 subunit 6B Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Phosducin-like protein Regulator of G-protein signaling 7 Regulator of G-protein signaling 9 T-complex protein 1 subunit alpha T-complex protein 1 subunit beta T-complex protein 1 subunit delta T-complex protein 1 subunit epsilon T-complex protein 1 subunit eta T-complex protein 1 subunit gamma T-complex protein 1 subunit theta T-complex protein 1 subunit zeta	A0A8I6AR12 D4ACB8 F7ELS2 F7FH41 O35353 P19139 P28480 P49803 P49805 P52287 P54311 P54313 P62882 P67874 Q5XIM9 Q63737 Q68FQ0 Q6AYJ7 Q6P502 Q7TPB1	Cct1 Cct2 Cct3 Cct4 Cct5 Cct6a Cct6b Cct7 Cct8 Ccta Cctb Ck2n Csnk2a1 Csnk2a2 Csnk2b Gnb1 Gnb2 Gnb3 Gnb4 Gnb5 LOC363658 Pdcl Rgs7 Rgs9 Tcp1	Rattus norvegicus (Norway rat)
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)	Cartilage intermediate layer protein Insulin-like growth factor 1 receptor Insulin-like growth factor I Insulin-like growth factor II	D3ZGB8 P01346 P08025 P24062	Cilp Igf-1 Igf-2 Igf1 Igf1r Igf2	Rattus norvegicus (Norway rat)
IL-6-type cytokine receptor ligand interactions	Cardiotrophin-1 Cardiotrophin-like cytokine factor 1 Ciliary neurotrophic factor receptor subunit alpha Ciliary neurotrophic factor Cytokine receptor-like factor 1 Interleukin 31 receptor A Interleukin 31 Interleukin-11 receptor subunit alpha Interleukin-11 Interleukin-6 receptor subunit beta Leukemia inhibitory factor receptor Leukemia inhibitory factor Oncostatin-M-specific receptor subunit beta Oncostatin-M Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Tyrosine-protein kinase	A0A8I5ZNP8 A0A8I6AM23 A0A8I6GGY9 D3ZD03 D3ZIV9 F1LZR4 O70535 P17777 P20294 P40190 Q08406 Q62689 Q63086 Q65Z14 Q65Z15 Q99MF4 Q99MF5	Clcf1 Cntf Cntfr Crlf1 Ctf1 Il11 Il11ra1 Il31 Il31ra Il6st Jak1 Jak2 Lif Lifr Osm Osmr Osmrb Tyk2	Rattus norvegicus (Norway rat)
Fibronectin matrix formation	Carcinoembryonic antigen-related cell adhesion molecule 1 Fibronectin Integrin beta-1 Integrin subunit alpha 5	A0A0G2K1E2 P04937 P16573 P49134	Ceacam1 Fn1 Itga5 Itgb1	Rattus norvegicus (Norway rat)
Reversible hydration of carbon dioxide	Carbonic anhydrase 14 Carbonic anhydrase 1 Carbonic anhydrase 2 Carbonic anhydrase 3 Carbonic anhydrase 4 Carbonic anhydrase 5A, mitochondrial Carbonic anhydrase 5B, mitochondrial Carbonic anhydrase Carbonic anhydrase Carbonic anhydrase Carbonic anhydrase	A0A8I6AHH2 B0BNN3 B5DFG6 F1LQ08 F7FAJ9 F7FL00 P14141 P27139 P43165 P48284 Q66HG6	Ca1 Ca2 Ca3 Ca4 Ca5 Ca5a Ca5b Car1 Car12 Car13 Car14 Car5b Car6 Car9	Rattus norvegicus (Norway rat)
PKA-mediated phosphorylation of key metabolic factors	Carbohydrate-responsive element-binding protein	Q8VIP2	Mlxipl Wbscr14	Rattus norvegicus (Norway rat)
Trafficking and processing of endosomal TLR	Canopy FGF signaling regulator 3 Cathepsin B Cathepsin K Cathepsin S Endoplasmin Legumain Procathepsin L Similar to Cathepsin L precursor (Major excreted protein) (MEP) Toll-like receptor 7 Toll-like receptor 8 Toll-like receptor 9 Unc-93 homolog B1, TLR signaling regulator	A0A8I6AM21 A5H300 D3ZDJ4 D3ZKC3 G3V828 M0RAA8 O35186 P00787 P07154 Q02765 Q66HD0 Q9R0J8	Cnpy3 Cts7l2 Ctsb Ctsk Ctsl Ctsl1 Ctsll3 Ctss Grp94 Hsp90b1 Hspc4 Lgmn Prsc1 RGD1308751 Tlr7 Tlr8 Tlr9 Tra1 Unc93b1	Rattus norvegicus (Norway rat)
Interleukin-35 Signalling	Calnexin Epstein-Barr virus induced 3 Interleukin 12 receptor subunit beta 2 Interleukin-12 subunit alpha Interleukin-6 receptor subunit beta Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 4 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Tyrosine-protein kinase	A0A0G2JX93 A0A8I6AM23 D3ZD03 F1LRH7 M0RD76 P35565 P40190 P52631 Q62689 Q9R103	Canx Ebi3 Il12a Il12rb2 Il6st Jak1 Jak2 Stat1 Stat3 Stat4 Tyk2	Rattus norvegicus (Norway rat)
Interleukin-27 signaling	Calnexin Cytokine receptor-like factor 1 Epstein-Barr virus induced 3 Interleukin 27 Interleukin-6 receptor subunit beta Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 4 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Tyrosine-protein kinase	A0A0G2JX93 A0A8I6AM23 D3ZD03 D3ZIV9 D3ZPW3 M0RD76 P35565 P40190 P52631 Q62689	Canx Crlf1 Ebi3 Il27 Il6st Jak1 Jak2 Stat1 Stat3 Stat4 Tyk2	Rattus norvegicus (Norway rat)
Calnexin/calreticulin cycle	Calnexin Calreticulin Protein disulfide-isomerase A3	P11598 P18418 P35565	Calr Canx Erp60 Grp58 Pdia3	Rattus norvegicus (Norway rat)
Reduction of cytosolic Ca++ levels	Calmodulin-3 Plasma membrane calcium-transporting ATPase 1 Plasma membrane calcium-transporting ATPase 3 Plasma membrane calcium-transporting ATPase 4 Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 Sodium/calcium exchanger 1 Sodium/calcium exchanger 2 Sodium/calcium exchanger 3 Sorcin	A0A8I5Y9M9 P0DP31 P11505 P11507 P18596 P48768 P70549 Q01728 Q64542 Q64568 Q64578	Atp2a1 Atp2a2 Atp2a3 Atp2b1 Atp2b3 Atp2b4 CaMIII Calm3 Cam3 Camc Ncx1 Ncx2 Ncx3 Pmca3 Slc8a1 Slc8a2 Slc8a3 Sri	Rattus norvegicus (Norway rat)

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