neurodegenerative disease

Summary
Synonym
  • degenerative disease
Definition
A central nervous system disease that results in the progressive deterioration of function or structure of neurons.
Super Class
central nervous system disease
Disease Ontology
DOID:1289
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 81 - 90 of 106 in total
Gene ID Gene Symbol Description Source
26524 LATS2 large tumor suppressor kinase 2
29978 UBQLN2 ubiquilin 2
29979 UBQLN1 ubiquilin 1
51087 YBX2 Y-box binding protein 2
51422 PRKAG2 protein kinase AMP-activated non-catalytic subunit gamma 2
53335 BCL11A BCL11 transcription factor A
53632 PRKAG3 protein kinase AMP-activated non-catalytic subunit gamma 3
54893 MTMR10 myotubularin related protein 10
55666 NPLOC4 NPL4 homolog, ubiquitin recognition factor
56893 UBQLN4 ubiquilin 4
Displaying entries 1 - 10 of 73 in total
Gene ID Gene Symbol Description Source
11804 Aplp2 amyloid beta precursor-like protein 2
13424 Dync1h1 dynein cytoplasmic 1 heavy chain 1
13542 Dvl1 dishevelled segment polarity protein 1
13728 Mark2 MAP/microtubule affinity regulating kinase 2
13856 Epo erythropoietin
14473 Gc vitamin D binding protein
14799 Gria1 glutamate receptor, ionotropic, AMPA1 (alpha 1)
14800 Gria2 glutamate receptor, ionotropic, AMPA2 (alpha 2)
14802 Gria4 glutamate receptor, ionotropic, AMPA4 (alpha 4)
14807 Grik3 glutamate receptor, ionotropic, kainate 3
Displaying entries 11 - 20 of 33 in total
Gene ID Gene Symbol Description Source
29489 Dync1h1 dynein cytoplasmic 1 heavy chain 1
29559 Grik1 glutamate ionotropic receptor kainate type subunit 1
29627 Gria2 glutamate ionotropic receptor AMPA type subunit 2
29628 Gria3 glutamate ionotropic receptor AMPA type subunit 3
29629 Gria4 glutamate ionotropic receptor AMPA type subunit 4
50592 Gria1 glutamate ionotropic receptor AMPA type subunit 1
54257 Grik2 glutamate ionotropic receptor kainate type subunit 2
79250 Aco2 aconitase 2
84012 Slc1a6 solute carrier family 1 member 6
84024 Pon1 paraoxonase 1
Displaying entries 1 - 10 of 15 in total
Gene ID Gene Symbol Description Source
31002 Appl beta amyloid protein precursor-like
31902 Gga Golgi-localized, gamma-adaptin ear containing, ARF binding protein
33627 ft fat
33658 FIG4 FIG4 phosphoinositide 5-phosphatase
35784 Nup50 Nucleoporin 50kD
35851 ptc patched
36484 AttC Attacin-C
36635 Dro Drosocin
38218 drpr draper
38419 Drs Drosomycin
Displaying entries 11 - 19 of 19 in total
Gene ID Gene Symbol Description Source
437021 tspan36 tetraspanin 36
447803 pon1 paraoxonase 1
494492 slc17a6a solute carrier family 17 member 6a
560753 tpi1b triosephosphate isomerase 1b
563467 slc17a8 solute carrier family 17 member 8
791696 asic1a acid-sensing (proton-gated) ion channel 1a
100004455 epoa erythropoietin a
100006041 rhoab ras homolog gene family, member Ab
100149756 slc17a6b solute carrier family 17 member 6b
Displaying all 3 entries
Gene ID Gene Symbol Description Source Organism
448598 pon2 paraoxonase 2 Xenopus tropicalis (tropical clawed frog)
780064 slc17a7 solute carrier family 17 (vesicular glutamate transporter), member 7 Xenopus tropicalis (tropical clawed frog)
100038162 tpi1 triosephosphate isomerase 1 Xenopus tropicalis (tropical clawed frog)
Displaying entries 1 - 10 of 15 in total
Gene ID Gene Symbol Description Source
173064 ced-1 Cell death abnormality protein 1
173631 ptc-3 Protein patched homolog 3
174274 ptc-1 Protein patched homolog 1;SSD domain-containing protein
175502 tir-1 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase;NAD(+) hydrolase tir-1;Sterile alpha and TIR motif-containing protein 1
176204 glr-1 Glutamate receptor 1
176291 eat-4 Major facilitator superfamily (MFS) profile domain-containing protein;putative vesicular glutamate transporter eat-4
176441 vglu-2 Major facilitator superfamily (MFS) profile domain-containing protein
176442 vglu-3 putative vesicular glutamate transporter vglu-3
177882 glt-3 Putative sodium-dependent excitatory amino acid transporter glt-3
180783 apl-1 Amyloid-beta-like protein
Displaying all 10 entries
Gene ID Gene Symbol Description Source
851013 ACO1 aconitate hydratase ACO1
851620 TPI1 triose-phosphate isomerase TPI1
853173 MTM1 Mtm1p
853770 BUD2 GTPase-activating protein BUD2
853792 OSI1 Osi1p
854943 NTE1 lysophospholipase
855392 FIG4 phosphatidylinositol-3,5-bisphosphate 5-phosphatase
855897 HRR25 serine/threonine protein kinase HRR25
856294 RHO1 Rho family GTPase RHO1
856422 RPN1 proteasome regulatory particle base subunit RPN1

About Release Notes Help Feedback

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


Logo License Policies Site Map

Contact: support@glycosmos.org

This work is licensed under Creative Commons Attribution 4.0 International


GlyCosmos Portal v4.1.0

Last updated: December 9, 2024