GlyCosmos Portal

Homo sapiens (human)

Summary

Taxonomy ID: 9606
PubChem Taxonomy: 9606

Genes (1582) Glycans (5831) Glycoproteins (18496) Lectins (298) Pathways (2090)

Displaying entries **1776 - 1800** of **2090** in total

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Pathway Name	Protein Name ▲	UniProt ID	Gene Symbol
MPS II - Hunter syndrome	Iduronate 2-sulfatase	P22304	IDS SIDS
Inhibition of nitric oxide production	Importin subunit alpha-5 Importin subunit beta-1 Nitric oxide synthase, inducible PPE family protein PPE2	P35228 P52294 P9WI47 Q14974	KPNA1 KPNB1 NOS2 NOS2A NTF97 PPE2 RCH2
Defective SLC6A18 may confer susceptibility to iminoglycinuria and/or hyperglycinuria	Inactive sodium-dependent neutral amino acid transporter B(0)AT3	Q96N87	B0AT3 SLC6A18 XTRP2
Defective SLC6A18 may confer susceptibility to iminoglycinuria and/or hyperglycinuria	Inactive sodium-dependent neutral amino acid transporter B(0)AT3	Q96N87	B0AT3 SLC6A18 XTRP2
IkBA variant leads to EDA-ID	Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta NF-kappa-B essential modulator NF-kappa-B inhibitor alpha Nuclear factor NF-kappa-B p100 subunit Nuclear factor NF-kappa-B p105 subunit Transcription factor p65	O14920 O15111 P19838 P25963 Q00653 Q04206 Q9Y6K9	CHUK FIP3 IKBA IKBKB IKBKG IKKA IKKB LYT10 MAD3 NEMO NFKB1 NFKB2 NFKB3 NFKBI NFKBIA RELA TCF16
IKBKB deficiency causes SCID	Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta NF-kappa-B essential modulator	O14920 O15111 Q9Y6K9	CHUK FIP3 IKBKB IKBKG IKKA IKKB NEMO TCF16
IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR)	Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta NF-kappa-B essential modulator	O14920 O15111 Q9Y6K9	CHUK FIP3 IKBKB IKBKG IKKA IKKB NEMO TCF16
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE)	Inhibitor of nuclear factor kappa-B kinase subunit epsilon Interferon regulatory factor 3 Interferon regulatory factor 7 Lymphocyte antigen 96 Monocyte differentiation antigen CD14 Optineurin Polyubiquitin-B Polyubiquitin-C Serine/threonine-protein kinase TBK1 TIR domain-containing adapter molecule 1 TIR domain-containing adapter molecule 2 TNF receptor-associated factor 3 TRAF family member-associated NF-kappa-B activator Toll-like receptor 4 Tyrosine-protein phosphatase non-receptor type 11 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00206 P08571 P0CG47 P0CG48 P62979 P62987 Q06124 Q13114 Q14164 Q14653 Q86XR7 Q8IUC6 Q92844 Q92985 Q96CV9 Q9UHD2 Q9Y6Y9	CAP-1 CD14 CRAF1 ESOP1 FIP2 GLC1E HIP7 HYPL IKBKE IKKE IKKI IRF3 IRF7 ITRAF KIAA0151 LY96 MD2 NAK NRP OPTN PRVTIRB PTP2C PTPN11 RPS27A SHPTP2 TANK TBK1 TICAM1 TICAM2 TIRAP3 TIRP TLR4 TRAF2 TRAF3 TRAFAMN TRAM TRIF UBA52 UBA80 UBB UBC UBCEP1 UBCEP2
TICAM1-dependent activation of IRF3/IRF7	Inhibitor of nuclear factor kappa-B kinase subunit epsilon Interferon regulatory factor 3 Interferon regulatory factor 7 Optineurin Polyubiquitin-B Polyubiquitin-C Serine/threonine-protein kinase TBK1 TIR domain-containing adapter molecule 1 TNF receptor-associated factor 3 TRAF family member-associated NF-kappa-B activator Toll-like receptor 3 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O15455 P0CG47 P0CG48 P62979 P62987 Q13114 Q14164 Q14653 Q8IUC6 Q92844 Q92985 Q96CV9 Q9UHD2	CAP-1 CRAF1 FIP2 GLC1E HIP7 HYPL IKBKE IKKE IKKI IRF3 IRF7 ITRAF KIAA0151 NAK NRP OPTN PRVTIRB RPS27A TANK TBK1 TICAM1 TLR3 TRAF2 TRAF3 TRAFAMN TRIF UBA52 UBA80 UBB UBC UBCEP1 UBCEP2
Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7	Inhibitor of nuclear factor kappa-B kinase subunit epsilon Lymphocyte antigen 96 Monocyte differentiation antigen CD14 Optineurin Polyubiquitin-B Polyubiquitin-C Serine/threonine-protein kinase TBK1 TIR domain-containing adapter molecule 1 TIR domain-containing adapter molecule 2 TNF receptor-associated factor 3 TRAF family member-associated NF-kappa-B activator Toll-like receptor 4 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00206 P08571 P0CG47 P0CG48 P62979 P62987 Q13114 Q14164 Q86XR7 Q8IUC6 Q92844 Q96CV9 Q9UHD2 Q9Y6Y9	CAP-1 CD14 CRAF1 ESOP1 FIP2 GLC1E HIP7 HYPL IKBKE IKKE IKKI ITRAF KIAA0151 LY96 MD2 NAK NRP OPTN PRVTIRB RPS27A TANK TBK1 TICAM1 TICAM2 TIRAP3 TIRP TLR4 TRAF2 TRAF3 TRAFAMN TRAM TRIF UBA52 UBA80 UBB UBC UBCEP1 UBCEP2
Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation	Inhibitor of nuclear factor kappa-B kinase subunit epsilon Optineurin Polyubiquitin-B Polyubiquitin-C Serine/threonine-protein kinase TBK1 TIR domain-containing adapter molecule 1 TNF receptor-associated factor 3 TRAF family member-associated NF-kappa-B activator Toll-like receptor 3 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O15455 P0CG47 P0CG48 P62979 P62987 Q13114 Q14164 Q8IUC6 Q92844 Q96CV9 Q9UHD2	CAP-1 CRAF1 FIP2 GLC1E HIP7 HYPL IKBKE IKKE IKKI ITRAF KIAA0151 NAK NRP OPTN PRVTIRB RPS27A TANK TBK1 TICAM1 TLR3 TRAF2 TRAF3 TRAFAMN TRIF UBA52 UBA80 UBB UBC UBCEP1 UBCEP2
Pyrophosphate hydrolysis	Inorganic pyrophosphatase 2, mitochondrial Inorganic pyrophosphatase Phospholysine phosphohistidine inorganic pyrophosphate phosphatase	Q15181 Q9H008 Q9H2U2	IOPPP LHPP PP PPA1 PPA2
Synthesis of IPs in the nucleus	Inositol hexakisphosphate kinase 1 Inositol hexakisphosphate kinase 2 Inositol polyphosphate multikinase Inositol-pentakisphosphate 2-kinase	Q8NFU5 Q92551 Q9H8X2 Q9UHH9	C9orf12 IHPK1 IHPK2 IMPK IP6K1 IP6K2 IPMK IPPK KIAA0263
Synthesis of IP2, IP, and Ins in the cytosol	Inositol monophosphatase 1 Inositol monophosphatase 2 Inositol oxygenase Inositol polyphosphate 1-phosphatase Inositol polyphosphate 4-phosphatase type II Inositol polyphosphate 5-phosphatase OCRL Inositol polyphosphate-4-phosphatase type I A Inositol polyphosphate-5-phosphatase A Inositol-3-phosphate synthase 1 Myotubularin-related protein 7 Myotubularin-related protein 9 Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A Synaptojanin-1 Type II inositol 1,4,5-trisphosphate 5-phosphatase	O14732 O15327 O43426 P29218 P32019 P49441 Q01968 Q14642 Q15735 Q96PE3 Q96QG7 Q9NPH2 Q9UGB7 Q9Y216	5PTASE ALDRL6 C8orf9 IMP.18P IMPA IMPA1 IMPA2 INO1 INPP1 INPP4A INPP4B INPP5A INPP5B INPP5J ISYNA1 KIAA0910 KSP32 MIOX MTMR7 MTMR8 MTMR9 OCRL OCRL1 OCRL2 PIB5PA PIPP RSOR SYNJ1
IRS-related events triggered by IGF1R	Insulin receptor substrate 1 Insulin receptor substrate 2 Insulin receptor substrate 4 Insulin-like growth factor 1 receptor Insulin-like growth factor I Insulin-like growth factor II	O14654 P01344 P05019 P08069 P35568 Q9Y4H2	IBP1 IGF1 IGF1R IGF2 IRS1 IRS2 IRS4
Signaling by Leptin	Insulin receptor substrate 1 Insulin receptor substrate 2 Leptin Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Suppressor of cytokine signaling 3 Tyrosine-protein kinase JAK2 Tyrosine-protein phosphatase non-receptor type 11	O14543 O60674 P35568 P40763 P41159 P42229 P51692 Q06124 Q9Y4H2	APRF CIS3 IRS1 IRS2 JAK2 LEP OB OBS PTP2C PTPN11 SHPTP2 SOCS3 SSI3 STAT3 STAT5 STAT5A STAT5B
IRS-mediated signalling	Insulin receptor substrate 1 Insulin receptor substrate 2 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	O00459 P27986 P35568 P42336 P42338 Q9Y4H2	GRB1 IRS1 IRS2 PIK3C1 PIK3CA PIK3CB PIK3R1 PIK3R2
Activated NTRK3 signals through PI3K	Insulin receptor substrate 1 NT-3 growth factor receptor Neurotrophin-3 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Proto-oncogene tyrosine-protein kinase Src	P12931 P20783 P27986 P35568 P42336 Q16288	GRB1 IRS1 NTF3 NTRK3 PIK3CA PIK3R1 SRC SRC1 TRKC
Signaling by Insulin receptor	Insulin receptor Insulin	P01308 P06213	INS INSR
Relaxin receptors	Insulin-like 3 Insulin-like peptide INSL5 Prorelaxin H2 Relaxin receptor 1 Relaxin receptor 2 Relaxin-3 receptor 1 Relaxin-3 receptor 2 Relaxin-3	P04090 P51460 Q8TDU9 Q8WXD0 Q8WXF3 Q9HBX9 Q9NSD7 Q9Y5Q6	GPCR135 GPCR142 GPR100 GPR106 GREAT INSL3 INSL5 INSL7 LGR7 LGR8 RLF RLN2 RLN3 RLN3R1 RLN3R2 RLNL RXFP1 RXFP2 RXFP3 RXFP4 RXN3 SALPR ZINS4
Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA	Insulin-like growth factor 2 mRNA-binding protein 1 Insulin-like growth factor 2 mRNA-binding protein 2 Insulin-like growth factor 2 mRNA-binding protein 3	O00425 Q9NZI8 Q9Y6M1	CRDBP IGF2BP1 IGF2BP2 IGF2BP3 IMP2 IMP3 KOC1 VICKZ1 VICKZ2 VICKZ3 ZBP1
Regulation of IFNA/IFNB signaling	Interferon alpha-1/13 Interferon alpha-10 Interferon alpha-14 Interferon alpha-16 Interferon alpha-17 Interferon alpha-21 Interferon alpha-2 Interferon alpha-4 Interferon alpha-5 Interferon alpha-6 Interferon alpha-7 Interferon alpha-8 Interferon alpha/beta receptor 1 Interferon beta Non-receptor tyrosine-protein kinase TYK2 Signal transducer and activator of transcription 2 Suppressor of cytokine signaling 1 Suppressor of cytokine signaling 3 Tyrosine-protein kinase JAK1 Tyrosine-protein phosphatase non-receptor type 11 Tyrosine-protein phosphatase non-receptor type 1 Tyrosine-protein phosphatase non-receptor type 6 Ubl carboxyl-terminal hydrolase 18	O14543 O15524 P01562 P01563 P01566 P01567 P01568 P01569 P01570 P01571 P01574 P05013 P05014 P05015 P17181 P18031 P23458 P29350 P29597 P32881 P52630 Q06124 Q9UMW8	CIS3 HCP IFB IFNA1 IFNA10 IFNA13 IFNA14 IFNA16 IFNA17 IFNA2 IFNA21 IFNA2A IFNA2B IFNA2C IFNA4 IFNA5 IFNA6 IFNA7 IFNA8 IFNAR IFNAR1 IFNB IFNB1 ISG43 JAK1 JAK1A JAK1B PTP1B PTP1C PTP2C PTPN1 PTPN11 PTPN6 SHPTP2 SOCS1 SOCS3 SSI1 SSI3 STAT2 TIP3 TYK2 USP18
IFNG signaling activates MAPKs	Interferon gamma receptor 1 Interferon gamma receptor 2 Interferon gamma Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 RAF proto-oncogene serine/threonine-protein kinase Tyrosine-protein kinase JAK1 Tyrosine-protein kinase JAK2	O60674 P01579 P04049 P15260 P23458 P27361 P28482 P38484	ERK1 ERK2 IFNG IFNGR1 IFNGR2 IFNGT1 JAK1 JAK1A JAK1B JAK2 MAPK1 MAPK3 PRKM1 PRKM2 PRKM3 RAF RAF1
Interleukin-20 family signaling	Interferon lambda receptor 1 Interferon lambda-1 Interferon lambda-2 Interferon lambda-3 Interleukin-10 receptor subunit beta Interleukin-19 Interleukin-20 receptor subunit alpha Interleukin-20 receptor subunit beta Interleukin-20 Interleukin-22 receptor subunit alpha-1 Interleukin-22 receptor subunit alpha-2 Interleukin-22 Interleukin-24 Interleukin-26 Non-receptor tyrosine-protein kinase TYK2 Signal transducer and activator of transcription 1-alpha/beta Signal transducer and activator of transcription 2 Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 4 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Tyrosine-protein kinase JAK1 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase JAK3 Tyrosine-protein phosphatase non-receptor type 11	O60674 P23458 P29597 P40763 P42224 P42229 P51692 P52333 P52630 Q06124 Q08334 Q13007 Q14765 Q6UXL0 Q8IU54 Q8IU57 Q8IZI9 Q8IZJ0 Q8N6P7 Q969J5 Q9GZX6 Q9NPH9 Q9NYY1 Q9UHD0 Q9UHF4	AK155 APRF CRFB4 D21S58 D21S66 DIRS1 IFNL1 IFNL2 IFNL3 IFNLR1 IL10RB IL19 IL20 IL20RA IL20RB IL22 IL22R IL22RA1 IL22RA2 IL24 IL26 IL28A IL28B IL28C IL28RA IL29 ILTIF JAK1 JAK1A JAK1B JAK2 JAK3 LICR2 MDA7 PTP2C PTPN11 SHPTP2 ST16 STAT1 STAT2 STAT3 STAT4 STAT5 STAT5A STAT5B TYK2 ZCYTO10 ZCYTO18 ZCYTO20 ZCYTO21 ZCYTO22 ZMDA1
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling	Interferon regulatory factor 7 Interleukin-1 receptor-associated kinase 1 Interleukin-1 receptor-associated kinase 4 Myeloid differentiation primary response protein MyD88 TNF receptor-associated factor 6 Toll-like receptor 7 Toll-like receptor 9 Ubiquitin-conjugating enzyme E2 N Ubiquitin-conjugating enzyme E2 variant 1	P51617 P61088 Q13404 Q92985 Q99836 Q9NR96 Q9NWZ3 Q9NYK1 Q9Y4K3	BLU CROC1 IRAK IRAK1 IRAK4 IRF7 MYD88 RNF85 TLR7 TLR9 TRAF6 UBE2N UBE2V UBE2V1 UEV1

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