GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **1701 - 1725** of **2090** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▲	Organism	GlyTouCan ID
Recycling of eIF2:GDP	Eukaryotic translation initiation factor 2 subunit 1 Eukaryotic translation initiation factor 2 subunit 2 Eukaryotic translation initiation factor 2 subunit 3 Translation initiation factor eIF2B subunit alpha Translation initiation factor eIF2B subunit beta Translation initiation factor eIF2B subunit delta Translation initiation factor eIF2B subunit epsilon Translation initiation factor eIF2B subunit gamma	P05198 P20042 P41091 P49770 Q13144 Q14232 Q9NR50 Q9UI10	EIF2A EIF2B EIF2B1 EIF2B2 EIF2B3 EIF2B4 EIF2B5 EIF2BA EIF2BB EIF2BD EIF2BE EIF2G EIF2S1 EIF2S2 EIF2S3	Homo sapiens (human)
SUMOylation of immune response proteins	E3 SUMO-protein ligase PIAS3 E3 SUMO-protein ligase PIAS4 E3 ubiquitin-protein ligase Topors Inhibitor of nuclear factor kappa-B kinase subunit epsilon Interferon-induced, double-stranded RNA-activated protein kinase NF-kappa-B essential modulator NF-kappa-B inhibitor alpha Nuclear factor NF-kappa-B p100 subunit SUMO-conjugating enzyme UBC9 Small ubiquitin-related modifier 1 Small ubiquitin-related modifier 3 Transcription factor p65	P19525 P25963 P55854 P63165 P63279 Q00653 Q04206 Q14164 Q8N2W9 Q9NS56 Q9Y6K9 Q9Y6X2	EIF2AK2 FIP3 IKBA IKBKE IKBKG IKKE IKKI KIAA0151 LUN LYT10 MAD3 NEMO NFKB2 NFKB3 NFKBI NFKBIA PIAS3 PIAS4 PIASG PKR PRKR RELA SMT3A SMT3C SMT3H1 SMT3H3 SUMO1 SUMO3 TOPORS TP53BPL UBC9 UBCE9 UBE2I UBL1	Homo sapiens (human)
Inhibition of PKR	Interferon-induced, double-stranded RNA-activated protein kinase Non-structural protein 1	P03496 P19525	EIF2AK2 NS PKR PRKR	Homo sapiens (human)
tRNA processing in the mitochondrion	3-hydroxyacyl-CoA dehydrogenase type-2 CCA tRNA nucleotidyltransferase 1, mitochondrial Mitochondrial ribonuclease P catalytic subunit Zinc phosphodiesterase ELAC protein 2 tRNA methyltransferase 10 homolog C	O15091 Q7L0Y3 Q96Q11 Q99714 Q9BQ52	ELAC2 ERAB HADH2 HPC2 HSD17B10 KIAA0391 MRPP1 MRPP2 MRPP3 PRORP RG9MTD1 SCHAD SDR5C1 TRMT10C TRNT1 XH98G2	Homo sapiens (human)
rRNA processing in the mitochondrion	3-hydroxyacyl-CoA dehydrogenase type-2 Mitochondrial ribonuclease P catalytic subunit Zinc phosphodiesterase ELAC protein 2 tRNA methyltransferase 10 homolog C	O15091 Q7L0Y3 Q99714 Q9BQ52	ELAC2 ERAB HADH2 HPC2 HSD17B10 KIAA0391 MRPP1 MRPP2 MRPP3 PRORP RG9MTD1 SCHAD SDR5C1 TRMT10C XH98G2	Homo sapiens (human)
MPS IV - Morquio syndrome B	Beta-galactosidase	P16278	ELNR1 GLB1	Homo sapiens (human)	G82768YB
Mitotic Metaphase/Anaphase Transition	F-box only protein 5 Serine/threonine-protein kinase PLK1	P53350 Q9UKT4	EMI1 FBX5 FBXO5 PLK PLK1	Homo sapiens (human)
Manipulation of host energy metabolism	6 kDa early secretory antigenic target Alpha-enolase Phosphoglycerate kinase 1	P00558 P06733 P9WNK7	ENO1 ENO1L1 MBPB1 MPB1 PGK1 PGKA esaT6 esxA	Homo sapiens (human)
Defective SLC29A3 causes histiocytosis-lymphadenopathy plus syndrome (HLAS)	Equilibrative nucleoside transporter 3	Q9BZD2	ENT3 SLC29A3	Homo sapiens (human)
Glycogen synthesis	1,4-alpha-glucan-branching enzyme E3 ubiquitin-protein ligase NHLRC1 Glycogen [starch] synthase, liver Glycogen [starch] synthase, muscle Glycogenin-1 Glycogenin-2 Laforin Phosphoglucomutase-1 Polyubiquitin-B Polyubiquitin-C Protein phosphatase 1 regulatory subunit 3C UTP--glucose-1-phosphate uridylyltransferase Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O15488 O95278 P0CG47 P0CG48 P13807 P36871 P46976 P54840 P62979 P62987 Q04446 Q16851 Q6VVB1 Q9UQK1	EPM2A EPM2B GBE1 GYG GYG1 GYG2 GYS GYS1 GYS2 NHLRC1 PGM1 PPP1R3C PPP1R5 RPS27A UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 UGP1 UGP2	Homo sapiens (human)
Myoclonic epilepsy of Lafora	E3 ubiquitin-protein ligase NHLRC1 Glycogen [starch] synthase, muscle Glycogenin-1 Laforin Polyubiquitin-B Polyubiquitin-C Protein phosphatase 1 regulatory subunit 3C Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O95278 P0CG47 P0CG48 P13807 P46976 P62979 P62987 Q6VVB1 Q9UQK1	EPM2A EPM2B GYG GYG1 GYS GYS1 NHLRC1 PPP1R3C PPP1R5 RPS27A UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Homo sapiens (human)
Erythropoietin activates Phosphoinositide-3-kinase (PI3K)	Erythropoietin receptor Erythropoietin GRB2-associated-binding protein 1 Insulin receptor substrate 2 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform Phosphoinositide 3-kinase regulatory subunit 5 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Lyn	O00329 O60674 P01588 P07948 P19235 P27986 P42336 P42338 P48736 Q13480 Q8WYR1 Q9Y4H2	EPO EPOR GAB1 GRB1 IRS2 JAK2 JTK8 LYN PIK3C1 PIK3CA PIK3CB PIK3CD PIK3CG PIK3R1 PIK3R5	Homo sapiens (human)
Erythropoietin activates Phospholipase C gamma (PLCG)	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 Erythropoietin receptor Erythropoietin Insulin receptor substrate 2 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Lyn	O60674 P01588 P07948 P16885 P19174 P19235 Q9Y4H2	EPO EPOR IRS2 JAK2 JTK8 LYN PLC1 PLCG1 PLCG2	Homo sapiens (human)
Erythropoietin activates STAT5	Erythropoietin receptor Erythropoietin Insulin receptor substrate 2 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Lyn	O60674 P01588 P07948 P19235 P42229 P51692 Q9Y4H2	EPO EPOR IRS2 JAK2 JTK8 LYN STAT5 STAT5A STAT5B	Homo sapiens (human)
Signaling by Erythropoietin	Erythropoietin receptor Erythropoietin Insulin receptor substrate 2 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Lyn	O60674 P01588 P07948 P19235 Q9Y4H2	EPO EPOR IRS2 JAK2 JTK8 LYN	Homo sapiens (human)
tRNA modification in the mitochondrion	3-hydroxyacyl-CoA dehydrogenase type-2 Mitochondrial ribonuclease P catalytic subunit Mitochondrial tRNA-specific 2-thiouridylase 1 Protein MTO1 homolog, mitochondrial tRNA (adenine(58)-N(1))-methyltransferase, mitochondrial tRNA dimethylallyltransferase tRNA methyltransferase 10 homolog C tRNA modification GTPase GTPBP3, mitochondrial	O15091 O75648 Q7L0Y3 Q969Y2 Q99714 Q9BVS5 Q9H3H1 Q9Y2Z2	ERAB GTPBP3 HADH2 HSD17B10 IPT KIAA0391 MOD5 MRPP1 MRPP2 MRPP3 MTGP1 MTO1 MTU1 PRORP RG9MTD1 SCHAD SDR5C1 TRIT1 TRMT1 TRMT10C TRMT61B TRMU XH98G2	Homo sapiens (human)
Interleukin-12 signaling	Interleukin-12 receptor subunit beta-1 Interleukin-12 receptor subunit beta-2 Interleukin-12 subunit alpha Interleukin-12 subunit beta Non-receptor tyrosine-protein kinase TYK2 Protein disulfide-isomerase Signal transducer and activator of transcription 4 Tyrosine-protein kinase JAK1 Tyrosine-protein kinase JAK2 Vesicle-associated membrane protein 7	O60674 P07237 P23458 P29459 P29460 P29597 P42701 P51809 Q14765 Q99665	ERBA2L IL12A IL12B IL12R IL12RB IL12RB1 IL12RB2 JAK1 JAK1A JAK1B JAK2 NKSF1 NKSF2 P4HB PDI PDIA1 PO4DB STAT4 SYBL1 TYK2 VAMP7	Homo sapiens (human)
GRB7 events in ERBB2 signaling	Growth factor receptor-bound protein 7 Pro-neuregulin-1, membrane-bound isoform Pro-neuregulin-2, membrane-bound isoform Receptor tyrosine-protein kinase erbB-2	O14511 P04626 Q02297 Q14451	ERBB2 GGF GRB7 HER2 HGL HRGA MLN19 NDF NEU NGL NRG1 NRG2 NTAK SMDF	Homo sapiens (human)
Transport to the Golgi and subsequent modification	Multiple coagulation factor deficiency protein 2 Protein ERGIC-53	P49257 Q8NI22	ERGIC53 F5F8D LMAN1 MCFD2 SDNSF	Homo sapiens (human)
STAT6-mediated induction of chemokines	Serine/threonine-protein kinase TBK1 Signal transducer and activator of transcription 6 Stimulator of interferon genes protein	P42226 Q86WV6 Q9UHD2	ERIS MITA NAK STAT6 STING STING1 TBK1 TMEM173	Homo sapiens (human)
FCERI mediated MAPK activation	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 Dual specificity mitogen-activated protein kinase kinase 4 Dual specificity mitogen-activated protein kinase kinase 7 GRB2-related adapter protein 2 GTPase HRas GTPase NRas Guanine nucleotide exchange factor VAV2 Guanine nucleotide exchange factor VAV3 IGHV7-81 protein Immunoglobulin heavy constant epsilon Immunoglobulin heavy variable 1-2 Immunoglobulin heavy variable 1-46 Immunoglobulin heavy variable 1-69 Immunoglobulin heavy variable 2-5 Immunoglobulin heavy variable 2-70 Immunoglobulin heavy variable 3-11 Immunoglobulin heavy variable 3-13 Immunoglobulin heavy variable 3-23 Immunoglobulin heavy variable 3-30 Immunoglobulin heavy variable 3-33 Immunoglobulin heavy variable 3-48 Immunoglobulin heavy variable 3-53 Immunoglobulin heavy variable 3-7 Immunoglobulin heavy variable 3-9 Immunoglobulin heavy variable 4-34 Immunoglobulin heavy variable 4-39 Immunoglobulin heavy variable 4-59 Immunoglobulin kappa constant Immunoglobulin kappa variable 1-12 Immunoglobulin kappa variable 1-16 Immunoglobulin kappa variable 1-17 Immunoglobulin kappa variable 1-33 Immunoglobulin kappa variable 1-39 Immunoglobulin kappa variable 1-5 Immunoglobulin kappa variable 1D-12 Immunoglobulin kappa variable 1D-16 Immunoglobulin kappa variable 1D-33 Immunoglobulin kappa variable 1D-39 Immunoglobulin kappa variable 2-28 Immunoglobulin kappa variable 2-29 Immunoglobulin kappa variable 2-30 Immunoglobulin kappa variable 2D-28 Immunoglobulin kappa variable 2D-30 Immunoglobulin kappa variable 2D-40 Immunoglobulin kappa variable 3-11 Immunoglobulin kappa variable 3-15 Immunoglobulin kappa variable 3-20 Immunoglobulin kappa variable 3D-20 Immunoglobulin kappa variable 4-1 Immunoglobulin kappa variable 5-2 Immunoglobulin lambda constant 1 Immunoglobulin lambda constant 2 Immunoglobulin lambda constant 3 Immunoglobulin lambda constant 6 Immunoglobulin lambda constant 7 Immunoglobulin lambda variable 1-40 Immunoglobulin lambda variable 1-44 Immunoglobulin lambda variable 1-47 Immunoglobulin lambda variable 1-51 Immunoglobulin lambda variable 2-11 Immunoglobulin lambda variable 2-14 Immunoglobulin lambda variable 2-23 Immunoglobulin lambda variable 2-8 Immunoglobulin lambda variable 3-19 Immunoglobulin lambda variable 3-1 Immunoglobulin lambda variable 3-21 Immunoglobulin lambda variable 3-25 Immunoglobulin lambda variable 3-27 Immunoglobulin lambda variable 6-57 Immunoglobulin lambda variable 7-43 Immunolglobulin kappa light chain variable region L22 (Fragment) Lymphocyte cytosolic protein 2 Mitogen-activated protein kinase 10 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Mitogen-activated protein kinase 8 Mitogen-activated protein kinase 9 Mitogen-activated protein kinase kinase kinase 1 Protein c-Fos Proto-oncogene vav Ras-related C3 botulinum toxin substrate 1 Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 2 Son of sevenless homolog 1 Transcription factor Jun Tyrosine-protein kinase Lyn Tyrosine-protein kinase SYK UGa8H (Fragment) V1-11 protein (Fragment) V1-13 protein (Fragment) V1-16 protein (Fragment) V1-20 protein (Fragment) V1-3 protein (Fragment) V1-5 protein (Fragment) V1-7 protein (Fragment) V1-9 protein (Fragment) V2-11 protein (Fragment) V2-15 protein (Fragment) V2-17 protein (Fragment) V2-19 protein (Fragment) V2-8 protein (Fragment) V3-2 protein (Fragment) V3-3 protein (Fragment) V3-4 protein (Fragment) V4-1 protein (Fragment) V4-2 protein (Fragment) V4-6 protein (Fragment) V5-1 protein (Fragment) V5-4 protein (Fragment) V5-6 protein (Fragment)	A0A075B6P5 A0A075B6S6 A0A0C4DH25 A0A0C4DH73 A0M8Q6 A2KUC3 A2NJV5 A2NXD2 O14733 O75791 P01100 P01111 P01112 P01593 P01594 P01597 P01599 P01601 P01602 P01611 P01614 P01615 P01619 P01624 P01699 P01700 P01701 P01703 P01704 P01705 P01706 P01709 P01714 P01715 P01717 P01718 P01721 P01742 P01743 P01762 P01763 P01764 P01766 P01767 P01768 P01772 P01780 P01782 P01814 P01817 P01824 P01825 P01834 P01854 P04211 P04430 P04432 P04433 P05412 P06310 P06312 P06315 P06331 P07948 P0CF74 P0CG04 P0DOY2 P0DOY3 P15498 P16885 P19174 P23083 P27361 P28482 P43405 P45983 P45984 P45985 P52735 P53779 P63000 P80748 Q07889 Q13094 Q13153 Q13177 Q13233 Q5NV61 Q5NV62 Q5NV64 Q5NV65 Q5NV66 Q5NV67 Q5NV68 Q5NV69 Q5NV75 Q5NV79 Q5NV80 Q5NV81 Q5NV82 Q5NV83 Q5NV84 Q5NV85 Q5NV86 Q5NV87 Q5NV89 Q5NV90 Q5NV91 Q5NV92 Q6PIL0 Q9UKW4	ERK1 ERK2 FOS G0S7 GADS GRAP2 GRB2L GRID HRAS HRAS1 IGHE IGHV IGHV1-2 IGHV1-46 IGHV1-69 IGHV2-5 IGHV2-70 IGHV3-11 IGHV3-13 IGHV3-23 IGHV3-30 IGHV3-33 IGHV3-48 IGHV3-53 IGHV3-7 IGHV3-9 IGHV4-34 IGHV4-39 IGHV4-59 IGHV7-81 IGKC IGKV1-12 IGKV1-16 IGKV1-17 IGKV1-33 IGKV1-39 IGKV1-5 IGKV1D-12 IGKV1D-16 IGKV1D-33 IGKV1D-39 IGKV2-28 IGKV2-29 IGKV2-30 IGKV2D-28 IGKV2D-30 IGKV2D-40 IGKV3-11 IGKV3-15 IGKV3-20 IGKV3D-20 IGKV4-1 IGKV5-2 IGLC1 IGLC2 IGLC3 IGLC6 IGLC7 IGLV IGLV1-40 IGLV1-44 IGLV1-47 IGLV1-51 IGLV2-11 IGLV2-14 IGLV2-23 IGLV2-8 IGLV3-1 IGLV3-19 IGLV3-21 IGLV3-25 IGLV3-27 IGLV6-57 IGLV7-43 JNK1 JNK2 JNK3 JNK3A JNKK1 JNKK2 JTK8 JUN LCP2 LYN MAP2K4 MAP2K7 MAP3K1 MAPK1 MAPK10 MAPK3 MAPK8 MAPK9 MAPKKK1 MEK4 MEK7 MEKK MEKK1 MKK4 MKK7 NRAS PAK1 PAK2 PLC1 PLCG1 PLCG2 PRKM1 PRKM10 PRKM2 PRKM3 PRKM8 PRKM9 PRKMK4 PRKMK7 RAC1 SAPK1 SAPK1A SAPK1B SAPK1C SEK1 SERK1 SKK1 SKK4 SOS1 SYK TC25 V1-11 V1-13 V1-16 V1-20 V1-3 V1-5 V1-7 V1-9 V2-11 V2-15 V2-17 V2-19 V2-8 V3-2 V3-3 V3-4 V4-1 V4-2 V4-6 V5-1 V5-4 V5-6 VAV VAV1 VAV2 VAV3	Homo sapiens (human)
Signal attenuation	Growth factor receptor-bound protein 10 Insulin receptor substrate 1 Insulin receptor substrate 2 Insulin receptor Insulin Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 SHC-transforming protein 1 Son of sevenless homolog 1	P01308 P06213 P27361 P28482 P29353 P35568 Q07889 Q13322 Q9Y4H2	ERK1 ERK2 GRB10 GRBIR INS INSR IRS1 IRS2 KIAA0207 MAPK1 MAPK3 PRKM1 PRKM2 PRKM3 SHC SHC1 SHCA SOS1	Homo sapiens (human)
IFNG signaling activates MAPKs	Interferon gamma receptor 1 Interferon gamma receptor 2 Interferon gamma Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 RAF proto-oncogene serine/threonine-protein kinase Tyrosine-protein kinase JAK1 Tyrosine-protein kinase JAK2	O60674 P01579 P04049 P15260 P23458 P27361 P28482 P38484	ERK1 ERK2 IFNG IFNGR1 IFNGR2 IFNGT1 JAK1 JAK1A JAK1B JAK2 MAPK1 MAPK3 PRKM1 PRKM2 PRKM3 RAF RAF1	Homo sapiens (human)
RSK activation	3-phosphoinositide-dependent protein kinase 1 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Ribosomal protein S6 kinase alpha-1 Ribosomal protein S6 kinase alpha-2 Ribosomal protein S6 kinase alpha-3 Ribosomal protein S6 kinase alpha-6	O15530 P27361 P28482 P51812 Q15349 Q15418 Q9UK32	ERK1 ERK2 ISPK1 MAPK1 MAPK3 MAPKAPK1A MAPKAPK1B MAPKAPK1C PDK1 PDPK1 PRKM1 PRKM2 PRKM3 RPS6KA1 RPS6KA2 RPS6KA3 RPS6KA6 RSK1 RSK2 RSK3 RSK4	Homo sapiens (human)
Signaling by MAP2K mutants	Dual specificity mitogen-activated protein kinase kinase 1 Dual specificity mitogen-activated protein kinase kinase 2 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3	P27361 P28482 P36507 Q02750	ERK1 ERK2 MAP2K1 MAP2K2 MAPK1 MAPK3 MEK1 MEK2 MKK2 PRKM1 PRKM2 PRKM3 PRKMK1 PRKMK2	Homo sapiens (human)

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