GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **1951 - 1975** of **2090** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▼	Organism	GlyTouCan ID
Cargo recognition for clathrin-mediated endocytosis	AP-2 complex subunit alpha-1 AP-2 complex subunit alpha-2 AP-2 complex subunit beta AP-2 complex subunit mu AP-2 complex subunit sigma AP2-associated protein kinase 1 Adaptin ear-binding coat-associated protein 1 Adaptin ear-binding coat-associated protein 2 Amphiregulin Apolipoprotein B-100 Arf-GAP domain and FG repeat-containing protein 1 Beta-2 adrenergic receptor Beta-adrenergic receptor kinase 1 Beta-arrestin-1 Beta-arrestin-2 COP9 signalosome complex subunit 1 COP9 signalosome complex subunit 2 COP9 signalosome complex subunit 3 COP9 signalosome complex subunit 4 COP9 signalosome complex subunit 5 COP9 signalosome complex subunit 6 COP9 signalosome complex subunit 7a COP9 signalosome complex subunit 7b COP9 signalosome complex subunit 8 Cation-dependent mannose-6-phosphate receptor Cation-independent mannose-6-phosphate receptor Clathrin coat assembly protein AP180 Clathrin heavy chain 1 Clathrin heavy chain 2 Clathrin light chain A Clathrin light chain B Cystic fibrosis transmembrane conductance regulator Disabled homolog 2 Dyslexia-associated protein KIAA0319 E3 ubiquitin-protein ligase CBL Endophilin-A1 Endophilin-A2 Endophilin-A3 Epidermal growth factor receptor substrate 15-like 1 Epidermal growth factor receptor substrate 15 Epidermal growth factor receptor Epigen Epsin-1 Epsin-2 F-BAR domain only protein 1 F-BAR domain only protein 2 Frizzled-4 G protein-coupled receptor kinase 3 Hepatocyte growth factor-regulated tyrosine kinase substrate Interleukin-7 receptor subunit alpha Intersectin-1 Intersectin-2 Low density lipoprotein receptor adapter protein 1 Low-density lipoprotein receptor-related protein 2 Low-density lipoprotein receptor Lysosome membrane protein 2 Muscarinic acetylcholine receptor M2 NEDD8 Phosphatidylinositol-binding clathrin assembly protein Polyubiquitin-B Polyubiquitin-C Pro-epidermal growth factor Probetacellulin Proepiregulin Proheparin-binding EGF-like growth factor Protein Wnt-5a Protransforming growth factor alpha RalBP1-associated Eps domain-containing protein 1 RalBP1-associated Eps domain-containing protein 2 SH3 domain-containing kinase-binding protein 1 SH3-containing GRB2-like protein 3-interacting protein 1 Segment polarity protein dishevelled homolog DVL-2 Serotransferrin Signal transducing adapter molecule 1 Signal transducing adapter molecule 2 Solute carrier family 2, facilitated glucose transporter member 8 Stonin-1 Stonin-2 Substance-P receptor Synaptotagmin-11 Synaptotagmin-1 Synaptotagmin-2 Synaptotagmin-8 Synaptotagmin-9 T-cell surface glycoprotein CD3 delta chain T-cell surface glycoprotein CD3 gamma chain T-cell surface glycoprotein CD4 Torsin-1A Torsin-1B Trans-Golgi network integral membrane protein 2 Transferrin receptor protein 1 Type-1 angiotensin II receptor Ubiquilin-1 Ubiquilin-2 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Vasopressin V2 receptor Vasopressin-neurophysin 2-copeptin Vesicle-associated membrane protein 2 Vesicle-associated membrane protein 3 Vesicle-associated membrane protein 4 Vesicle-associated membrane protein 7 Vesicle-associated membrane protein 8 Vesicular acetylcholine transporter	O14526 O14641 O14656 O14657 O14944 O14964 O43493 O60641 O75379 O75886 O94973 O95208 O95782 P00533 P01130 P01133 P01135 P01185 P01730 P02786 P02787 P04114 P04234 P07550 P08172 P09496 P09497 P09693 P0CG47 P0CG48 P11717 P13569 P15514 P16871 P20645 P21579 P22681 P25098 P25103 P30518 P30556 P32121 P35070 P35626 P41221 P42566 P49407 P51809 P52594 P53675 P53680 P61201 P62979 P62987 P63010 P63027 P98082 P98164 Q00610 Q0JRZ9 Q13098 Q13492 Q14108 Q15811 Q15836 Q15843 Q16572 Q2M2I8 Q5SW96 Q5VV43 Q6UW88 Q7L5N1 Q86SS6 Q8N9I0 Q8NBV8 Q8NC96 Q8NFH8 Q8WXE9 Q92783 Q92905 Q96B97 Q96CW1 Q96D71 Q99075 Q99627 Q99961 Q99962 Q99963 Q9BQI5 Q9BT78 Q9BT88 Q9BV40 Q9H9Q2 Q9NVZ3 Q9NY64 Q9NZM3 Q9UBC2 Q9UBW8 Q9UHD9 Q9ULV1 Q9UMX0 Q9UNS2 Q9Y6I3 Q9Y6Q2	AAK1 ABCC7 ADHR ADRB2 ADRB2R ADRBK1 ADRBK2 ADTAA ADTAB ADTB2 AF1P AGFG1 AGTR1 AGTR1A AGTR1B AP17 AP2A1 AP2A2 AP2B1 AP2M1 AP2S1 APOB ARB2 AREG AREGB ARH ARR1 ARR2 ARRB1 ARRB2 ARVP AT2R1 AT2R1B AVP AVPR2 B2AR BARK BARK1 BARK2 BTC CALM CBL CBL2 CD36L2 CD3D CD3G CD4 CFTR CHRM2 CIN85 CLAPA1 CLAPA2 CLAPB1 CLAPM1 CLAPS2 CLH17 CLH22 CLTA CLTB CLTC CLTCL CLTCL1 CLTCL2 CLTD CNSA1 CNSA2 CNSA3 COPS1 COPS2 COPS3 COPS4 COPS5 COPS6 COPS7A COPS7B COPS8 CSN1 CSN2 CSN3 CSN4 CSN5 CSN6 CSN7A CSN7B CSN8 DA41 DAB2 DERP10 DIR DIR3 DOC2 DQ1 DQ2 DTR DTS DVL2 DYT1 EGF EGFR EPGN EPN1 EPN2 EPS15 EPS15L1 EPS15R ERBB ERBB1 EREG FCHO1 FCHO2 FZD4 GLUT8 GLUTX1 GPS1 GRK2 GRK3 HBEGF HBP HEGFL HER1 HGS HIP9 HRB HRS HVIP HYPJ IGF2R IL7R ITSN ITSN1 ITSN2 JAB1 KIAA0034 KIAA0080 KIAA0109 KIAA0290 KIAA0319 KIAA0656 KIAA0899 KIAA1048 KIAA1065 KIAA1256 LDLR LDLRAP1 LIMP2 LIMPII LRP2 M6PR MPR46 MPRD MPRI N4BP4 NECAP1 NECAP2 NEDD8 NK1R PICALM PLIC1 PLIC2 POB1 RAB REPS1 REPS2 RIP RNF55 RPS27A SALF SBLF SCARB2 SDGF SGIP1 SH3D1A SH3D1B SH3D2A SH3D2B SH3D2C SH3GL1 SH3GL2 SH3GL3 SH3KBP1 SLC18A3 SLC2A8 SNAP91 STAM STAM1 STAM2 STN1 STN2 STNB STON1 STON2 SVP65 SWAP SYB2 SYB3 SYBL1 SYT SYT1 SYT11 SYT2 SYT8 SYT9 T3D T3G TA TAC1R TACR1 TF TFRC TGFA TGN46 TGN51 TGOLN2 TOR1A TOR1B TORA TRIP15 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 UBQLN1 UBQLN2 V2R VACHT VAMP2 VAMP3 VAMP4 VAMP7 VAMP8 VP WNT5A	Homo sapiens (human)
Clathrin-mediated endocytosis	ADP-ribosylation factor 6 ADP-ribosylation factor GTPase-activating protein 1 AP-2 complex subunit alpha-1 AP-2 complex subunit alpha-2 AP-2 complex subunit beta AP-2 complex subunit mu AP-2 complex subunit sigma AP2-associated protein kinase 1 Actin nucleation-promoting factor WASL Actin-related protein 2/3 complex subunit 1A Actin-related protein 2/3 complex subunit 2 Actin-related protein 2/3 complex subunit 3 Actin-related protein 2/3 complex subunit 4 Actin-related protein 2/3 complex subunit 5 Actin-related protein 2 Actin-related protein 3 Adaptin ear-binding coat-associated protein 1 Adaptin ear-binding coat-associated protein 2 Amphiphysin Amphiregulin Apolipoprotein B-100 Arf-GAP domain and FG repeat-containing protein 1 Auxilin Beta-2 adrenergic receptor Beta-arrestin-1 Beta-arrestin-2 Cation-dependent mannose-6-phosphate receptor Cation-independent mannose-6-phosphate receptor Cdc42-interacting protein 4 Clathrin coat assembly protein AP180 Clathrin heavy chain 1 Clathrin heavy chain 2 Clathrin light chain A Clathrin light chain B Cyclin-G-associated kinase Cystic fibrosis transmembrane conductance regulator Disabled homolog 2 Dynamin-1 Dynamin-2 Dynamin-3 Dyslexia-associated protein KIAA0319 E3 ubiquitin-protein ligase CBL Endophilin-A1 Endophilin-A2 Endophilin-A3 Epidermal growth factor receptor substrate 15-like 1 Epidermal growth factor receptor substrate 15 Epidermal growth factor receptor Epigen Epsin-1 Epsin-2 F-BAR domain only protein 1 F-BAR domain only protein 2 Formin-binding protein 1-like Formin-binding protein 1 Frizzled-4 GTPase-activating protein and VPS9 domain-containing protein 1 Heat shock cognate 71 kDa protein Hepatocyte growth factor-regulated tyrosine kinase substrate Huntingtin-interacting protein 1-related protein Huntingtin-interacting protein 1 Inositol polyphosphate 5-phosphatase OCRL Interleukin-7 receptor subunit alpha Intersectin-1 Intersectin-2 Low density lipoprotein receptor adapter protein 1 Low-density lipoprotein receptor-related protein 2 Low-density lipoprotein receptor Lysosome membrane protein 2 Muscarinic acetylcholine receptor M2 Myc box-dependent-interacting protein 1 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma Phosphatidylinositol-binding clathrin assembly protein Polyubiquitin-B Polyubiquitin-C Pro-epidermal growth factor Probetacellulin Proepiregulin Proheparin-binding EGF-like growth factor Protein Wnt-5a Protein kinase C and casein kinase substrate in neurons protein 1 Protein kinase C and casein kinase substrate in neurons protein 2 Protein kinase C and casein kinase substrate in neurons protein 3 Protransforming growth factor alpha RalBP1-associated Eps domain-containing protein 1 RalBP1-associated Eps domain-containing protein 2 Ras-related protein Rab-5A Ras-related protein Rab-5B Ras-related protein Rab-5C SH3 domain-containing kinase-binding protein 1 SH3-containing GRB2-like protein 3-interacting protein 1 Segment polarity protein dishevelled homolog DVL-2 Serotransferrin Signal transducing adapter molecule 1 Signal transducing adapter molecule 2 Solute carrier family 2, facilitated glucose transporter member 8 Sorting nexin-18 Sorting nexin-9 Src substrate cortactin Stonin-1 Stonin-2 Substance-P receptor Synaptojanin-1 Synaptojanin-2 Synaptotagmin-11 Synaptotagmin-1 Synaptotagmin-2 Synaptotagmin-8 Synaptotagmin-9 T-cell surface glycoprotein CD3 delta chain T-cell surface glycoprotein CD3 gamma chain T-cell surface glycoprotein CD4 Trans-Golgi network integral membrane protein 2 Transferrin receptor protein 1 Type-1 angiotensin II receptor Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Vasopressin V2 receptor Vasopressin-neurophysin 2-copeptin Vesicle-associated membrane protein 2 Vesicle-associated membrane protein 3 Vesicle-associated membrane protein 4 Vesicle-associated membrane protein 7 Vesicle-associated membrane protein 8 Vesicular acetylcholine transporter	O00291 O00401 O00443 O00499 O14526 O14641 O14944 O14964 O14976 O15056 O15144 O15145 O15511 O43426 O43493 O60331 O60641 O75061 O75146 O75379 O75886 O94973 O95208 O95782 P00533 P01130 P01133 P01135 P01185 P01730 P02786 P02787 P04114 P04234 P07550 P08172 P09496 P09497 P09693 P0CG47 P0CG48 P11142 P11717 P13569 P15514 P16871 P20339 P20645 P21579 P22681 P25103 P30518 P30556 P32121 P35070 P41221 P42566 P49407 P49418 P50570 P51148 P51809 P52594 P53675 P53680 P59998 P61020 P61158 P61160 P62330 P62979 P62987 P63010 P63027 P98082 P98164 Q00610 Q01968 Q05193 Q0JRZ9 Q13492 Q14108 Q14247 Q14C86 Q15642 Q15811 Q15836 Q16572 Q2M2I8 Q5SW96 Q5T0N5 Q5VV43 Q6UW88 Q86SS6 Q8N6T3 Q8N9I0 Q8NBV8 Q8NC96 Q8NFH8 Q8WXE9 Q92747 Q92783 Q96B97 Q96CW1 Q96D71 Q96RF0 Q96RU3 Q99075 Q99961 Q99962 Q99963 Q9BQI5 Q9BT88 Q9BV40 Q9BY11 Q9NVZ3 Q9NY64 Q9NZM3 Q9UBC2 Q9UKS6 Q9ULV1 Q9UNF0 Q9UQ16 Q9Y5X1 Q9Y6I3 Q9Y6Q2	AAK1 ABCC7 ACTR2 ACTR3 ADHR ADRB2 ADRB2R ADTAA ADTAB ADTB2 AF1P AGFG1 AGTR1 AGTR1A AGTR1B AMPH AMPH1 AMPHL AP17 AP2A1 AP2A2 AP2B1 AP2M1 AP2S1 APOB ARB2 ARC16 ARC20 ARC21 ARC34 AREG AREGB ARF1GAP ARF6 ARFGAP1 ARH ARP2 ARP3 ARPC1A ARPC2 ARPC3 ARPC4 ARPC5 ARR1 ARR2 ARRB1 ARRB2 ARVP AT2R1 AT2R1B AVP AVPR2 B2AR BIN1 BTC C1orf39 CALM CBL CBL2 CD36L2 CD3D CD3G CD4 CFTR CHRM2 CIN85 CIP4 CLAPA1 CLAPA2 CLAPB1 CLAPM1 CLAPS2 CLH17 CLH22 CLTA CLTB CLTC CLTCL CLTCL1 CLTCL2 CLTD CNSA1 CNSA2 CNSA3 CTTN DAB2 DIR DIR3 DNAJC26 DNAJC6 DNM DNM1 DNM2 DNM3 DOC2 DTR DTS DVL2 DYN2 EGF EGFR EMS1 EPGN EPN1 EPN2 EPS15 EPS15L1 EPS15R ERBB ERBB1 EREG FBP17 FCHO1 FCHO2 FNBP1 FNBP1L FZD4 GAK GAPEX5 GAPVD1 GLUT8 GLUTX1 HBEGF HBP HEGFL HER1 HGS HIP1 HIP12 HIP1R HIP9 HRB HRS HSC70 HSP73 HSPA10 HSPA8 HYPJ IGF2R IL7R ITSN ITSN1 ITSN2 KIAA0034 KIAA0080 KIAA0109 KIAA0290 KIAA0319 KIAA0348 KIAA0473 KIAA0554 KIAA0589 KIAA0655 KIAA0656 KIAA0820 KIAA0899 KIAA0910 KIAA1048 KIAA1065 KIAA1256 KIAA1379 KIAA1521 LDLR LDLRAP1 LIMP2 LIMPII LRP2 M6PR MPR46 MPRD MPRI NECAP1 NECAP2 NK1R OCRL OCRL1 PACSIN1 PACSIN2 PACSIN3 PICALM PIK3C2A PIP5K1C POB1 RAB RAB5 RAB5A RAB5B RAB5C RABL RAP6 REPS1 REPS2 RIP RNF55 RPS27A SALF SBLF SCARB2 SDGF SGIP1 SH3D1A SH3D1B SH3D2A SH3D2B SH3D2C SH3GL1 SH3GL2 SH3GL3 SH3KBP1 SH3PX1 SH3PXD3A SH3PXD3B SLC18A3 SLC2A8 SNAP91 SNX18 SNX9 SOP2L STAM STAM1 STAM2 STN1 STN2 STNB STON1 STON2 STOT STP SVP65 SWAP SYB2 SYB3 SYBL1 SYNJ1 SYNJ2 SYT SYT1 SYT11 SYT2 SYT8 SYT9 T3D T3G TAC1R TACR1 TF TFRC TGFA TGN46 TGN51 TGOLN2 TOCA1 TRIP10 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 V2R VACHT VAMP2 VAMP3 VAMP4 VAMP7 VAMP8 VP WASL WNT5A	Homo sapiens (human)
Displacement of DNA glycosylase by APEX1	DNA repair nuclease/redox regulator APEX1 DNA-3-methyladenine glycosylase Endonuclease III-like protein 1 G/T mismatch-specific thymine DNA glycosylase Methyl-CpG-binding domain protein 4 N-glycosylase/DNA lyase Single-strand selective monofunctional uracil DNA glycosylase	O15527 O95243 P27695 P29372 P78549 Q13569 Q53HV7	AAG ANPG APE APE1 APEX APEX1 APX HAP1 MBD4 MED1 MID1 MMH MPG MUTM NTH1 NTHL1 OCTS3 OGG1 OGH1 REF1 SMUG1 TDG	Homo sapiens (human)
Recognition and association of DNA glycosylase with site containing an affected purine	Adrenocortical dysplasia protein homolog DNA-3-methyladenine glycosylase Endonuclease 8-like 3 Histone H2A type 1-B/E Histone H2A type 1-C Histone H2A type 1-D Histone H2A type 1-J Histone H2A type 2-A Histone H2A type 2-C Histone H2A-Bbd type 1 Histone H2A.J Histone H2A.V Histone H2AX Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/F/G/I Histone H2B type 1-D Histone H2B type 1-H Histone H2B type 1-J Histone H2B type 1-K Histone H2B type 1-L Histone H2B type 1-M Histone H2B type 1-N Histone H2B type 1-O Histone H2B type 2-E Histone H2B type 3-B Histone H2B type F-S Histone H3.1t Histone H4 N-glycosylase/DNA lyase Protection of telomeres protein 1 TERF1-interacting nuclear factor 2 Telomeric repeat-binding factor 1 Telomeric repeat-binding factor 2-interacting protein 1 Telomeric repeat-binding factor 2	O15527 O60814 P04908 P06899 P0C5Y9 P16104 P20671 P23527 P29372 P33778 P54274 P57053 P58876 P62805 P62807 Q15554 Q16695 Q16777 Q16778 Q6FI13 Q71UI9 Q8N257 Q8TAT5 Q93077 Q93079 Q96A08 Q96AP0 Q99877 Q99878 Q99879 Q99880 Q9BSI4 Q9BTM1 Q9NUX5 Q9NYB0	AAG ACD ANPG DRIP5 H2AB1 H2AC14 H2AC18 H2AC19 H2AC20 H2AC4 H2AC6 H2AC7 H2AC8 H2AFA H2AFB1 H2AFE H2AFG H2AFJ H2AFL H2AFM H2AFO H2AFQ H2AFV H2AFX H2AJ H2AV H2AX H2AZ2 H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H2BFA H2BFB H2BFC H2BFD H2BFE H2BFF H2BFG H2BFH H2BFJ H2BFK H2BFL H2BFN H2BFQ H2BFR H2BFS H2BFT H2BS1 H2BU1 H3-4 H3FT H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HIRIP1 HIRIP2 HIST1H2AB HIST1H2AC HIST1H2AD HIST1H2AE HIST1H2AJ HIST1H2BA HIST1H2BB HIST1H2BC HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2BI HIST1H2BJ HIST1H2BK HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H2AA HIST2H2AA3 HIST2H2AA4 HIST2H2AC HIST2H2BE HIST2H4 HIST2H4A HIST2H4B HIST3H2BB HIST3H3 HIST4H4 MID1 MMH MPG MUTM NEIL3 OGG1 OGH1 PIN2 PIP1 POT1 PTOP RAP1 TERF1 TERF2 TERF2IP TIN2 TINF2 TINT1 TPP1 TRBF1 TRBF2 TRF TRF1 TRF2 TSH2B	Homo sapiens (human)
Cleavage of the damaged purine	Adrenocortical dysplasia protein homolog DNA-3-methyladenine glycosylase Endonuclease 8-like 3 Histone H2A type 1-B/E Histone H2A type 1-C Histone H2A type 1-D Histone H2A type 1-J Histone H2A type 2-A Histone H2A type 2-C Histone H2A-Bbd type 1 Histone H2A.J Histone H2A.V Histone H2AX Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/F/G/I Histone H2B type 1-D Histone H2B type 1-H Histone H2B type 1-J Histone H2B type 1-K Histone H2B type 1-L Histone H2B type 1-M Histone H2B type 1-N Histone H2B type 1-O Histone H2B type 2-E Histone H2B type 3-B Histone H2B type F-S Histone H3.1t Histone H4 N-glycosylase/DNA lyase Protection of telomeres protein 1 TERF1-interacting nuclear factor 2 Telomeric repeat-binding factor 1 Telomeric repeat-binding factor 2-interacting protein 1 Telomeric repeat-binding factor 2	O15527 O60814 P04908 P06899 P0C5Y9 P16104 P20671 P23527 P29372 P33778 P54274 P57053 P58876 P62805 P62807 Q15554 Q16695 Q16777 Q16778 Q6FI13 Q71UI9 Q8N257 Q8TAT5 Q93077 Q93079 Q96A08 Q96AP0 Q99877 Q99878 Q99879 Q99880 Q9BSI4 Q9BTM1 Q9NUX5 Q9NYB0	AAG ACD ANPG DRIP5 H2AB1 H2AC14 H2AC18 H2AC19 H2AC20 H2AC4 H2AC6 H2AC7 H2AC8 H2AFA H2AFB1 H2AFE H2AFG H2AFJ H2AFL H2AFM H2AFO H2AFQ H2AFV H2AFX H2AJ H2AV H2AX H2AZ2 H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H2BFA H2BFB H2BFC H2BFD H2BFE H2BFF H2BFG H2BFH H2BFJ H2BFK H2BFL H2BFN H2BFQ H2BFR H2BFS H2BFT H2BS1 H2BU1 H3-4 H3FT H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HIRIP1 HIRIP2 HIST1H2AB HIST1H2AC HIST1H2AD HIST1H2AE HIST1H2AJ HIST1H2BA HIST1H2BB HIST1H2BC HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2BI HIST1H2BJ HIST1H2BK HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H2AA HIST2H2AA3 HIST2H2AA4 HIST2H2AC HIST2H2BE HIST2H4 HIST2H4A HIST2H4B HIST3H2BB HIST3H3 HIST4H4 MID1 MMH MPG MUTM NEIL3 OGG1 OGH1 PIN2 PIP1 POT1 PTOP RAP1 TERF1 TERF2 TERF2IP TIN2 TINF2 TINT1 TPP1 TRBF1 TRBF2 TRF TRF1 TRF2 TSH2B	Homo sapiens (human)
Catecholamine biosynthesis	Aromatic-L-amino-acid decarboxylase Dopamine beta-hydroxylase Phenylethanolamine N-methyltransferase Tyrosine 3-monooxygenase	P07101 P09172 P11086 P20711	AADC DBH DDC PENT PNMT TH TYH	Homo sapiens (human)
Serotonin and melatonin biosynthesis	Acetylserotonin O-methyltransferase Aromatic-L-amino-acid decarboxylase Serotonin N-acetyltransferase Tryptophan 5-hydroxylase 1 Tryptophan 5-hydroxylase 2	P17752 P20711 P46597 Q16613 Q8IWU9	AADC AANAT ASMT DDC NTPH SNAT TPH TPH1 TPH2 TPRH TRPH	Homo sapiens (human)
Tryptophan catabolism	2-amino-3-carboxymuconate-6-semialdehyde decarboxylase 3-hydroxyanthranilate 3,4-dioxygenase Amino acid transporter heavy chain SLC3A2 Indoleamine 2,3-dioxygenase 1 Indoleamine 2,3-dioxygenase 2 Kynureninase Kynurenine 3-monooxygenase Kynurenine formamidase Kynurenine--oxoglutarate transaminase 1 Kynurenine--oxoglutarate transaminase 3 Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial Large neutral amino acids transporter small subunit 1 Neutral amino acid uniporter 4 Tryptophan 2,3-dioxygenase	O15229 P08195 P14902 P46952 P48775 Q01650 Q16719 Q16773 Q63HM1 Q6YBV0 Q6YP21 Q6ZQW0 Q8N5Z0 Q8TDX5	AADAT ACMSD AFMID CCBL1 CCBL2 CD98LC HAAO IDO IDO1 IDO2 INDO INDOL1 KAT2 KAT3 KMO KYAT1 KYAT2 KYAT3 KYNU LAT1 MDU1 MPE16 PAT4 SLC36A4 SLC3A2 SLC7A5 TDO TDO2	Homo sapiens (human)
Lysine catabolism	2-oxoadipate dehydrogenase complex component E1 5-phosphohydroxy-L-lysine phospho-lyase Alpha-aminoadipic semialdehyde dehydrogenase Alpha-aminoadipic semialdehyde synthase, mitochondrial Dihydrolipoyl dehydrogenase, mitochondrial Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial Glutaryl-CoA dehydrogenase, mitochondrial Hydroxylysine kinase Ketimine reductase mu-crystallin Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial Mitochondrial 2-oxodicarboxylate carrier Peroxisomal sarcosine oxidase	A2RU49 P09622 P36957 P49419 Q14894 Q8IUZ5 Q8N5Z0 Q92947 Q96HY7 Q9BQT8 Q9P0Z9 Q9UDR5	AADAT AASS AGPHD1 AGXT2L2 ALDH7A1 ATQ1 CRYM DHTKD1 DLD DLST DLTS GCDH GCSL HYKK KAT2 KIAA1630 KYAT2 LAD LPIPOX ODC PHE3 PHYKPL PIPOX PSO SLC25A21 THBP	Homo sapiens (human)
LDL clearance	AP-2 complex subunit alpha-1 AP-2 complex subunit alpha-2 AP-2 complex subunit beta AP-2 complex subunit mu AP-2 complex subunit sigma Apolipoprotein B-100 Carboxylesterase 3 Clathrin heavy chain 1 Clathrin light chain A Lipolysis-stimulated lipoprotein receptor Low density lipoprotein receptor adapter protein 1 Low-density lipoprotein receptor Lysosomal acid lipase/cholesteryl ester hydrolase NPC intracellular cholesterol transporter 1 NPC intracellular cholesterol transporter 2 Neutral cholesterol ester hydrolase 1 Proprotein convertase subtilisin/kexin type 9 Sterol O-acyltransferase 1 Sterol O-acyltransferase 2	O15118 O75908 O94973 O95782 P01130 P04114 P09496 P35610 P38571 P53680 P61916 P63010 Q00610 Q5SW96 Q6PIU2 Q6UWW8 Q86X29 Q8NBP7 Q96CW1	AADACL1 ACACT ACACT1 ACACT2 ACAT ACAT1 ACAT2 ADTAA ADTAB ADTB2 AP17 AP2A1 AP2A2 AP2B1 AP2M1 AP2S1 APOB ARH CES3 CLAPA1 CLAPA2 CLAPB1 CLAPM1 CLAPS2 CLH17 CLTA CLTC CLTCL2 HE1 HIP9 HYPJ ILDR3 KIAA0034 KIAA0109 KIAA0899 KIAA1363 LDLR LDLRAP1 LIPA LISCH LSR NARC1 NCEH1 NPC1 NPC2 PCSK9 SOAT SOAT1 SOAT2 STAT	Homo sapiens (human)
Phase I - Functionalization of compounds	Aldehyde dehydrogenase, dimeric NADP-preferring Amine oxidase [copper-containing] 2 Amine oxidase [copper-containing] 3 Aryl hydrocarbon receptor nuclear translocator 2 Aryl hydrocarbon receptor nuclear translocator Aryl hydrocarbon receptor repressor Aryl hydrocarbon receptor Arylacetamide deacetylase Carbonyl reductase [NADPH] 3 Carboxylesterase 3 Carboxymethylenebutenolidase homolog Cocaine esterase Cytochrome P450 2B6 Cytochrome P450 3A4 Cytochrome b5 type B Diamine oxidase [copper-containing] Epoxide hydrolase 1 Liver carboxylesterase 1 Mitochondrial amidoxime reducing component 2 Mitochondrial amidoxime-reducing component 1 NADH-cytochrome b5 reductase 3 Ribosyldihydronicotinamide dehydrogenase [quinone] Valacyclovir hydrolase	A9YTQ3 O00748 O43169 O75106 O75828 P00387 P07099 P08684 P16083 P19801 P20813 P22760 P23141 P27540 P30838 P35869 Q16853 Q5VT66 Q6UWW8 Q86WA6 Q969Z3 Q96DG6 Q9HBZ2	AADAC ABP ABP1 AHR AHRR ALDH3 ALDH3A1 AOC1 AOC2 AOC3 ARNT ARNT2 BHLHE1 BHLHE2 BHLHE76 BHLHE77 BPHL CBR3 CES1 CES2 CES3 CMBL CYB5B CYB5M CYB5R3 CYP2B6 CYP3A3 CYP3A4 DAC DAO DIA1 EPHX EPHX1 EPOX ICE KIAA0307 KIAA1234 MARC1 MARC2 MCNAA MOSC1 MOSC2 MTARC1 MTARC2 NMOR2 NQO2 OMB5 SDR21C2 SES1 VAP1	Homo sapiens (human)
Synthesis of Ketone Bodies	3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic Acetoacetyl-CoA synthetase Acetyl-CoA acetyltransferase, mitochondrial Acyl-CoA synthetase short-chain family member 3, mitochondrial D-beta-hydroxybutyrate dehydrogenase, mitochondrial Dehydrogenase/reductase SDR family member 6 Hydroxymethylglutaryl-CoA lyase, mitochondrial Hydroxymethylglutaryl-CoA synthase, mitochondrial	P24752 P35914 P54868 Q02338 Q86V21 Q8TB92 Q9BUT1 Q9H6R3	AACS ACAT ACAT1 ACSF1 ACSS3 BDH BDH1 BDH2 DHRS6 HMGCL HMGCLL1 HMGCS2 MAT SDR15C1 SDR9C1	Homo sapiens (human)
Influenza Virus Induced Apoptosis	ADP/ATP translocase 3 Neuraminidase Protein PB1-F2 Transforming growth factor beta-1 proprotein	P01137 P03468 P0C0U1 P12236	AAC3 ANT3 NA PB1 SLC25A6 TGFB TGFB1	Homo sapiens (human)
Mitochondrial protein import	4-hydroxybenzoate polyprenyltransferase, mitochondrial 60 kDa heat shock protein, mitochondrial ADP/ATP translocase 1 ADP/ATP translocase 3 ATP synthase F(0) complex subunit C1, mitochondrial ATP synthase subunit alpha, mitochondrial ATP synthase subunit beta, mitochondrial Aconitate hydratase, mitochondrial COX assembly mitochondrial protein 2 homolog Citrate synthase, mitochondrial Coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial Coiled-coil-helix-coiled-coil-helix domain-containing protein 2 Coiled-coil-helix-coiled-coil-helix domain-containing protein 5 Coiled-coil-helix-coiled-coil-helix domain-containing protein 7 Cx9C motif-containing protein 4 Cytochrome c oxidase assembly factor 4 homolog, mitochondrial Cytochrome c oxidase assembly factor 6 homolog Cytochrome c oxidase assembly protein COX19 Cytochrome c oxidase copper chaperone Cytochrome c1, heme protein, mitochondrial Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial FAD-linked sulfhydryl oxidase ALR Frataxin, mitochondrial GrpE protein homolog 1, mitochondrial GrpE protein homolog 2, mitochondrial Iron-sulfur cluster co-chaperone protein HscB Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial MICOS complex subunit MIC19 Metaxin-1 Metaxin-2 Mitochondrial chaperone BCS1 Mitochondrial import inner membrane translocase subunit TIM14 Mitochondrial import inner membrane translocase subunit TIM16 Mitochondrial import inner membrane translocase subunit TIM44 Mitochondrial import inner membrane translocase subunit TIM50 Mitochondrial import inner membrane translocase subunit Tim10 B Mitochondrial import inner membrane translocase subunit Tim10 Mitochondrial import inner membrane translocase subunit Tim13 Mitochondrial import inner membrane translocase subunit Tim17-A Mitochondrial import inner membrane translocase subunit Tim17-B Mitochondrial import inner membrane translocase subunit Tim21 Mitochondrial import inner membrane translocase subunit Tim22 Mitochondrial import inner membrane translocase subunit Tim23 Mitochondrial import inner membrane translocase subunit Tim8 A Mitochondrial import inner membrane translocase subunit Tim8 B Mitochondrial import inner membrane translocase subunit Tim9 Mitochondrial import receptor subunit TOM20 homolog Mitochondrial import receptor subunit TOM22 homolog Mitochondrial import receptor subunit TOM40 homolog Mitochondrial import receptor subunit TOM5 homolog Mitochondrial import receptor subunit TOM6 homolog Mitochondrial import receptor subunit TOM7 homolog Mitochondrial import receptor subunit TOM70 Mitochondrial intermembrane space import and assembly protein 40 Mitochondrial-processing peptidase subunit alpha Mitochondrial-processing peptidase subunit beta NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial Ornithine transcarbamylase, mitochondrial Presequence protease, mitochondrial Probable D-lactate dehydrogenase, mitochondrial Sorting and assembly machinery component 50 homolog Stress-70 protein, mitochondrial Tafazzin Voltage-dependent anion-selective channel protein 1	O14925 O43615 O60220 O60830 O75390 O75431 O75439 O75746 O94826 O95169 O96008 P00480 P05496 P06576 P08574 P10809 P12235 P12236 P21796 P25705 P38646 P51553 P55789 P56277 P62072 Q10713 Q13505 Q14061 Q15388 Q16595 Q16635 Q3ZCQ8 Q49B96 Q5JRX3 Q5JTJ3 Q86WU2 Q8IWL3 Q8N4H5 Q8N4Q1 Q8TAA5 Q8WYQ3 Q96B49 Q96DA6 Q96H96 Q99595 Q99798 Q9BSY4 Q9BUK0 Q9BVV7 Q9HAV7 Q9NRP2 Q9NS69 Q9NX63 Q9NYJ1 Q9P0U1 Q9UJS0 Q9Y276 Q9Y3D7 Q9Y512 Q9Y584 Q9Y5J6 Q9Y5J7 Q9Y5J9 Q9Y5L4 Q9Y6H1	AAC1 AAC3 ACO2 AGC1 ALR ANT1 ANT3 ARALAR1 ATP5A ATP5A1 ATP5AL2 ATP5B ATP5F1A ATP5F1B ATP5G1 ATP5MC1 ATPM ATPMB ATPSB BCS1 BCS1L C16orf61 C18orf55 C19orf1 C1orf31 C22orf16 C2orf9 C6.1B C7orf17 C9orf105 CHCHD10 CHCHD2 CHCHD3 CHCHD4 CHCHD5 CHCHD7 CHCHD8 CL640 CMC2 CMC4 COA4 COA6 COQ2 COX17 COX19 CS CYC1 DDP DDP1 DDP2 DDPL DNAJC19 DNAJC20 E2IG2 EFE2 FRDA FXC1 FXN G4.5 GFER GREPEL1 GRP75 GRPEL1 GRPEL2 HERV1 HPO HSC20 HSCB HSP60 HSPA9 HSPA9B HSPD1 IDH3G INPP5E KIAA0016 KIAA0123 KIAA0719 KIAA1104 LDHD MAGMAS MIA40 MIC19 MIMT17 MIMT44 MINOS3 MP1 MPPA MPPB MTCP1 MTCP1NB MTX MTX1 MTX2 MTXN NDUFB8 OBTP OTC PAM16 PEREC1 PITRM1 PMPCA PMPCB PREP SAM50 SAMM50 SLC25A12 SLC25A13 SLC25A4 SLC25A6 TAFAZZIN TAZ TEX4 TIM10 TIM13B TIM14 TIM16 TIM17 TIM17A TIM17B TIM21 TIM22 TIM23 TIM44 TIM50 TIM8A TIM8B TIM9 TIM9A TIM9B TIMM10 TIMM10B TIMM13 TIMM13A TIMM13B TIMM14 TIMM16 TIMM17 TIMM17A TIMM17B TIMM21 TIMM22 TIMM23 TIMM44 TIMM50 TIMM8A TIMM8B TIMM9 TIMM9A TIMM9B TOM22 TOM40 TOM5 TOM6 TOM7 TOM70 TOMM07 TOMM20 TOMM22 TOMM40 TOMM5 TOMM6 TOMM7 TOMM70 TOMM70A VDAC VDAC1 X25 mt-HSP70	Homo sapiens (human)
Acetylation	Arylamine N-acetyltransferase 1 Arylamine N-acetyltransferase 2	P11245 P18440	AAC1 AAC2 NAT1 NAT2	Homo sapiens (human)
APAP ADME	ATP-binding cassette sub-family C member 2 ATP-binding cassette sub-family C member 3 ATP-binding cassette sub-family C member 4 ATP-binding cassette sub-family C member 5 Aminoacylase-1 Arylamine N-acetyltransferase 1 Arylamine N-acetyltransferase 2 Broad substrate specificity ATP-binding cassette transporter ABCG2 Cytochrome P450 2E1 Cytosolic non-specific dipeptidase Glutathione S-transferase Mu 1 Glutathione S-transferase P Glutathione S-transferase theta-1 Glutathione hydrolase 1 proenzyme Glutathione hydrolase 5 proenzyme Glutathione hydrolase 6 Glutathione hydrolase 7 Multidrug resistance-associated protein 1 Putative glutathione hydrolase 3 proenzyme Sulfotransferase 1A1 Sulfotransferase 1A3 Sulfotransferase 1A4 Sulfotransferase 1C4 Sulfotransferase 1E1 Sulfotransferase 2A1 UDP-glucuronosyltransferase 1-6 UDP-glucuronosyltransferase 1A10 UDP-glucuronosyltransferase 1A1 UDP-glucuronosyltransferase 1A9 UDP-glucuronosyltransferase 2B15	A6NGU5 O15438 O15439 O15440 O60656 O75897 P05181 P09211 P09488 P0DMM9 P0DMN0 P11245 P18440 P19224 P19440 P22309 P30711 P33527 P36269 P49888 P50225 P54855 Q03154 Q06520 Q6P531 Q92887 Q96KP4 Q9HAW8 Q9UJ14 Q9UNQ0	AAC1 AAC2 ABCC1 ABCC2 ABCC3 ABCC4 ABCC5 ABCG2 ABCP ACY1 BCRP BCRP1 CMOAT CMOAT1 CMOAT2 CMRP CN2 CNDP2 CPGL CYP2E CYP2E1 FAEES3 GGT GGT1 GGT3 GGT3P GGT5 GGT6 GGT7 GGTL3 GGTL5 GGTLA1 GNT1 GST1 GST3 GSTM1 GSTP1 GSTT1 HEL-S-13 HST MLP2 MOATB MRP MRP1 MRP2 MRP3 MRP4 MRP5 MXR NAT1 NAT2 PEPA STD STE STM STP STP1 SULT1A1 SULT1A3 SULT1A4 SULT1C2 SULT1C4 SULT1E1 SULT2A1 UGT1 UGT1A1 UGT1A10 UGT1A6 UGT1A9 UGT2B15 UGT2B8	Homo sapiens (human)
Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization	ADP/ATP translocase 1 ADP/ATP translocase 2 ADP/ATP translocase 3 Protein Vpr	P05141 P12235 P12236 P69726	AAC1 AAC2 AAC3 ANT1 ANT2 ANT3 SLC25A4 SLC25A5 SLC25A6 vpr	Homo sapiens (human)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane	ADP-ribosylation factor-like protein 2-binding protein ADP-ribosylation factor-like protein 2 ADP/ATP translocase 1 ADP/ATP translocase 2 ADP/ATP translocase 3 Equilibrative nucleoside transporter 1 Equilibrative nucleoside transporter 2 Equilibrative nucleoside transporter 3 Equilibrative nucleoside transporter 4 Sodium/nucleoside cotransporter 1 Sodium/nucleoside cotransporter 2 Solute carrier family 28 member 3	O00337 O43868 P05141 P12235 P12236 P36404 Q14542 Q7RTT9 Q99808 Q9BZD2 Q9HAS3 Q9Y2Y0	AAC1 AAC2 AAC3 ANT1 ANT2 ANT3 ARL2 ARL2BP BART BART1 CNT1 CNT2 CNT3 DER12 ENT1 ENT2 ENT3 ENT4 HNP36 PMAT SLC25A4 SLC25A5 SLC25A6 SLC28A1 SLC28A2 SLC28A3 SLC29A1 SLC29A2 SLC29A3 SLC29A4	Homo sapiens (human)
SUMOylation of SUMOylation proteins	Aladin E3 SUMO-protein ligase PIAS4 E3 SUMO-protein ligase RanBP2 E3 ubiquitin-protein ligase Topors Nuclear envelope pore membrane protein POM 121 Nuclear envelope pore membrane protein POM 121C Nuclear pore complex protein Nup107 Nuclear pore complex protein Nup133 Nuclear pore complex protein Nup153 Nuclear pore complex protein Nup155 Nuclear pore complex protein Nup160 Nuclear pore complex protein Nup205 Nuclear pore complex protein Nup214 Nuclear pore complex protein Nup50 Nuclear pore complex protein Nup85 Nuclear pore complex protein Nup88 Nuclear pore complex protein Nup93 Nuclear pore glycoprotein p62 Nuclear pore membrane glycoprotein 210 Nucleoporin NDC1 Nucleoporin NUP188 Nucleoporin NUP35 Nucleoporin NUP42 Nucleoporin Nup37 Nucleoporin Nup43 Nucleoporin p54 Nucleoprotein TPR Protein SEC13 homolog SUMO-conjugating enzyme UBC9 Small ubiquitin-related modifier 1 Small ubiquitin-related modifier 2 mRNA export factor RAE1	A8CG34 O15504 O75694 P12270 P35658 P37198 P49790 P49792 P55735 P57740 P61956 P63165 P63279 P78406 Q12769 Q5SRE5 Q7Z3B4 Q8N1F7 Q8N2W9 Q8NFH3 Q8NFH4 Q8NFH5 Q8TEM1 Q8WUM0 Q92621 Q96HA1 Q99567 Q9BTX1 Q9BW27 Q9NRG9 Q9NS56 Q9UKX7	AAAS ADRACALA C7orf14 CAIN CAN CG1 D3S1231E KIAA0023 KIAA0095 KIAA0169 KIAA0197 KIAA0225 KIAA0618 KIAA0791 KIAA0906 LUN MP44 MRNP41 NDC1 NPAP60L NUP107 NUP120 NUP121 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP358 NUP37 NUP42 NUP43 NUP50 NUP53 NUP54 NUP62 NUP75 NUP85 NUP88 NUP93 NUPL2 PCNT1 PIAS4 PIASG POM121 POM121A POM121C RAE1 RANBP2 SEC13 SEC13A SEC13L1 SEC13R SMT3B SMT3C SMT3H2 SMT3H3 SUMO1 SUMO2 TMEM48 TOPORS TP53BPL TPR UBC9 UBCE9 UBE2I UBL1	Homo sapiens (human)
Transport of Ribonucleoproteins into the Host Nucleus	Aladin E3 SUMO-protein ligase RanBP2 Importin subunit alpha-5 Importin subunit beta-1 Nuclear envelope pore membrane protein POM 121 Nuclear envelope pore membrane protein POM 121C Nuclear pore complex protein Nup107 Nuclear pore complex protein Nup133 Nuclear pore complex protein Nup153 Nuclear pore complex protein Nup155 Nuclear pore complex protein Nup160 Nuclear pore complex protein Nup205 Nuclear pore complex protein Nup214 Nuclear pore complex protein Nup50 Nuclear pore complex protein Nup85 Nuclear pore complex protein Nup88 Nuclear pore complex protein Nup93 Nuclear pore glycoprotein p62 Nuclear pore membrane glycoprotein 210 Nucleoporin NDC1 Nucleoporin NUP188 Nucleoporin NUP35 Nucleoporin NUP42 Nucleoporin Nup37 Nucleoporin Nup43 Nucleoporin p54 Nucleoprotein TPR Nucleoprotein Polymerase acidic protein Polymerase basic protein 2 Protein SEC13 homolog RNA-directed RNA polymerase catalytic subunit mRNA export factor RAE1	A8CG34 O15504 O75694 P03428 P03431 P03433 P03466 P12270 P35658 P37198 P49790 P49792 P52294 P55735 P57740 P78406 Q12769 Q14974 Q5SRE5 Q7Z3B4 Q8N1F7 Q8NFH3 Q8NFH4 Q8NFH5 Q8TEM1 Q8WUM0 Q92621 Q96HA1 Q99567 Q9BTX1 Q9BW27 Q9NRG9 Q9UKX7	AAAS ADRACALA C7orf14 CAIN CAN CG1 D3S1231E KIAA0023 KIAA0095 KIAA0169 KIAA0197 KIAA0225 KIAA0618 KIAA0791 KIAA0906 KPNA1 KPNB1 MP44 MRNP41 NDC1 NP NPAP60L NTF97 NUP107 NUP120 NUP121 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP358 NUP37 NUP42 NUP43 NUP50 NUP53 NUP54 NUP62 NUP75 NUP85 NUP88 NUP93 NUPL2 PA PB1 PB2 PCNT1 POM121 POM121A POM121C RAE1 RANBP2 RCH2 SEC13 SEC13A SEC13L1 SEC13R TMEM48 TPR	Homo sapiens (human)
Viral Messenger RNA Synthesis	Aladin DNA-directed RNA polymerase II subunit RPB11-a DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 E3 SUMO-protein ligase RanBP2 General transcription factor IIF subunit 1 General transcription factor IIF subunit 2 Nuclear envelope pore membrane protein POM 121 Nuclear envelope pore membrane protein POM 121C Nuclear pore complex protein Nup107 Nuclear pore complex protein Nup133 Nuclear pore complex protein Nup153 Nuclear pore complex protein Nup155 Nuclear pore complex protein Nup160 Nuclear pore complex protein Nup205 Nuclear pore complex protein Nup214 Nuclear pore complex protein Nup50 Nuclear pore complex protein Nup85 Nuclear pore complex protein Nup88 Nuclear pore complex protein Nup93 Nuclear pore glycoprotein p62 Nuclear pore membrane glycoprotein 210 Nucleoporin NDC1 Nucleoporin NUP188 Nucleoporin NUP35 Nucleoporin NUP42 Nucleoporin Nup37 Nucleoporin Nup43 Nucleoporin p54 Nucleoprotein TPR Nucleoprotein Polymerase acidic protein Polymerase basic protein 2 Protein SEC13 homolog RNA-directed RNA polymerase catalytic subunit mRNA export factor RAE1	A8CG34 O15504 O15514 O75694 P03428 P03431 P03433 P03466 P12270 P13984 P19387 P19388 P24928 P30876 P35269 P35658 P36954 P37198 P49790 P49792 P52434 P52435 P53803 P55735 P57740 P61218 P62487 P62875 P78406 Q12769 Q5SRE5 Q7Z3B4 Q8N1F7 Q8NFH3 Q8NFH4 Q8NFH5 Q8TEM1 Q8WUM0 Q92621 Q96HA1 Q99567 Q9BTX1 Q9BW27 Q9NRG9 Q9UKX7	AAAS ADRACALA C7orf14 CAIN CAN CG1 D3S1231E GTF2F1 GTF2F2 KIAA0023 KIAA0095 KIAA0169 KIAA0197 KIAA0225 KIAA0618 KIAA0791 KIAA0906 MP44 MRNP41 NDC1 NP NPAP60L NUP107 NUP120 NUP121 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP358 NUP37 NUP42 NUP43 NUP50 NUP53 NUP54 NUP62 NUP75 NUP85 NUP88 NUP93 NUPL2 PA PB1 PB2 PCNT1 POLR2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J1 POLR2K POLR2L POLRF POM121 POM121A POM121C RAE1 RANBP2 RAP30 RAP74 RPB7 SEC13 SEC13A SEC13L1 SEC13R TMEM48 TPR	Homo sapiens (human)
Regulation of Glucokinase by Glucokinase Regulatory Protein	Aladin E3 SUMO-protein ligase RanBP2 Glucokinase regulatory protein Hexokinase-4 Nuclear envelope pore membrane protein POM 121 Nuclear envelope pore membrane protein POM 121C Nuclear pore complex protein Nup107 Nuclear pore complex protein Nup133 Nuclear pore complex protein Nup153 Nuclear pore complex protein Nup155 Nuclear pore complex protein Nup160 Nuclear pore complex protein Nup205 Nuclear pore complex protein Nup214 Nuclear pore complex protein Nup50 Nuclear pore complex protein Nup85 Nuclear pore complex protein Nup88 Nuclear pore complex protein Nup93 Nuclear pore glycoprotein p62 Nuclear pore membrane glycoprotein 210 Nucleoporin NDC1 Nucleoporin NUP188 Nucleoporin NUP35 Nucleoporin NUP42 Nucleoporin Nup37 Nucleoporin Nup43 Nucleoporin p54 Nucleoprotein TPR Protein SEC13 homolog mRNA export factor RAE1	A8CG34 O15504 O75694 P12270 P35557 P35658 P37198 P49790 P49792 P55735 P57740 P78406 Q12769 Q14397 Q5SRE5 Q7Z3B4 Q8N1F7 Q8NFH3 Q8NFH4 Q8NFH5 Q8TEM1 Q8WUM0 Q92621 Q96HA1 Q99567 Q9BTX1 Q9BW27 Q9NRG9 Q9UKX7	AAAS ADRACALA C7orf14 CAIN CAN CG1 D3S1231E GCK GCKR KIAA0023 KIAA0095 KIAA0169 KIAA0197 KIAA0225 KIAA0618 KIAA0791 KIAA0906 MP44 MRNP41 NDC1 NPAP60L NUP107 NUP120 NUP121 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP358 NUP37 NUP42 NUP43 NUP50 NUP53 NUP54 NUP62 NUP75 NUP85 NUP88 NUP93 NUPL2 PCNT1 POM121 POM121A POM121C RAE1 RANBP2 SEC13 SEC13A SEC13L1 SEC13R TMEM48 TPR	Homo sapiens (human)	G58161NS
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)	Aladin E3 SUMO-protein ligase RanBP2 Glucokinase regulatory protein Hexokinase-4 Nuclear envelope pore membrane protein POM 121 Nuclear envelope pore membrane protein POM 121C Nuclear pore complex protein Nup107 Nuclear pore complex protein Nup133 Nuclear pore complex protein Nup153 Nuclear pore complex protein Nup155 Nuclear pore complex protein Nup160 Nuclear pore complex protein Nup205 Nuclear pore complex protein Nup214 Nuclear pore complex protein Nup50 Nuclear pore complex protein Nup85 Nuclear pore complex protein Nup88 Nuclear pore complex protein Nup93 Nuclear pore glycoprotein p62 Nuclear pore membrane glycoprotein 210 Nucleoporin NDC1 Nucleoporin NUP188 Nucleoporin NUP35 Nucleoporin NUP42 Nucleoporin Nup37 Nucleoporin Nup43 Nucleoporin p54 Nucleoprotein TPR Protein SEC13 homolog mRNA export factor RAE1	A8CG34 O15504 O75694 P12270 P35557 P35658 P37198 P49790 P49792 P55735 P57740 P78406 Q12769 Q14397 Q5SRE5 Q7Z3B4 Q8N1F7 Q8NFH3 Q8NFH4 Q8NFH5 Q8TEM1 Q8WUM0 Q92621 Q96HA1 Q99567 Q9BTX1 Q9BW27 Q9NRG9 Q9UKX7	AAAS ADRACALA C7orf14 CAIN CAN CG1 D3S1231E GCK GCKR KIAA0023 KIAA0095 KIAA0169 KIAA0197 KIAA0225 KIAA0618 KIAA0791 KIAA0906 MP44 MRNP41 NDC1 NPAP60L NUP107 NUP120 NUP121 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP358 NUP37 NUP42 NUP43 NUP50 NUP53 NUP54 NUP62 NUP75 NUP85 NUP88 NUP93 NUPL2 PCNT1 POM121 POM121A POM121C RAE1 RANBP2 SEC13 SEC13A SEC13L1 SEC13R TMEM48 TPR	Homo sapiens (human)
NS1 Mediated Effects on Host Pathways	Aladin E3 SUMO-protein ligase RanBP2 Importin subunit alpha-1 Importin subunit alpha-3 Importin subunit alpha-4 Importin subunit alpha-5 Importin subunit alpha-6 Importin subunit alpha-8 Importin subunit beta-1 Non-structural protein 1 Nuclear envelope pore membrane protein POM 121 Nuclear envelope pore membrane protein POM 121C Nuclear pore complex protein Nup107 Nuclear pore complex protein Nup133 Nuclear pore complex protein Nup153 Nuclear pore complex protein Nup155 Nuclear pore complex protein Nup160 Nuclear pore complex protein Nup205 Nuclear pore complex protein Nup214 Nuclear pore complex protein Nup50 Nuclear pore complex protein Nup85 Nuclear pore complex protein Nup88 Nuclear pore complex protein Nup93 Nuclear pore glycoprotein p62 Nuclear pore membrane glycoprotein 210 Nucleoporin NDC1 Nucleoporin NUP188 Nucleoporin NUP35 Nucleoporin NUP42 Nucleoporin Nup37 Nucleoporin Nup43 Nucleoporin p54 Nucleoprotein TPR Protein SEC13 homolog Ubiquitin-like protein ISG15 mRNA export factor RAE1	A8CG34 A9QM74 O00505 O00629 O15131 O15504 O75694 P03496 P05161 P12270 P35658 P37198 P49790 P49792 P52292 P52294 P55735 P57740 P78406 Q12769 Q14974 Q5SRE5 Q7Z3B4 Q8N1F7 Q8NFH3 Q8NFH4 Q8NFH5 Q8TEM1 Q8WUM0 Q92621 Q96HA1 Q99567 Q9BTX1 Q9BW27 Q9NRG9 Q9UKX7	AAAS ADRACALA C7orf14 CAIN CAN CG1 D3S1231E G1P2 ISG15 KIAA0023 KIAA0095 KIAA0169 KIAA0197 KIAA0225 KIAA0618 KIAA0791 KIAA0906 KPNA1 KPNA2 KPNA3 KPNA4 KPNA5 KPNA7 KPNB1 MP44 MRNP41 NDC1 NPAP60L NS NTF97 NUP107 NUP120 NUP121 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP358 NUP37 NUP42 NUP43 NUP50 NUP53 NUP54 NUP62 NUP75 NUP85 NUP88 NUP93 NUPL2 PCNT1 POM121 POM121A POM121C QIP1 QIP2 RAE1 RANBP2 RCH1 RCH2 SEC13 SEC13A SEC13L1 SEC13R SRP1 TMEM48 TPR UCRP	Homo sapiens (human)
SUMOylation of ubiquitinylation proteins	Aladin E3 SUMO-protein ligase PIAS1 E3 SUMO-protein ligase PIAS4 E3 SUMO-protein ligase RanBP2 E3 ubiquitin-protein ligase Mdm2 Nuclear envelope pore membrane protein POM 121 Nuclear envelope pore membrane protein POM 121C Nuclear pore complex protein Nup107 Nuclear pore complex protein Nup133 Nuclear pore complex protein Nup153 Nuclear pore complex protein Nup155 Nuclear pore complex protein Nup160 Nuclear pore complex protein Nup205 Nuclear pore complex protein Nup214 Nuclear pore complex protein Nup50 Nuclear pore complex protein Nup85 Nuclear pore complex protein Nup88 Nuclear pore complex protein Nup93 Nuclear pore glycoprotein p62 Nuclear pore membrane glycoprotein 210 Nucleoporin NDC1 Nucleoporin NUP188 Nucleoporin NUP35 Nucleoporin NUP42 Nucleoporin Nup37 Nucleoporin Nup43 Nucleoporin p54 Nucleoprotein TPR Protein PML Protein SEC13 homolog SUMO-conjugating enzyme UBC9 Small ubiquitin-related modifier 1 Zinc finger protein RFP mRNA export factor RAE1 von Hippel-Lindau disease tumor suppressor	A8CG34 O15504 O75694 O75925 P12270 P14373 P29590 P35658 P37198 P40337 P49790 P49792 P55735 P57740 P63165 P63279 P78406 Q00987 Q12769 Q5SRE5 Q7Z3B4 Q8N1F7 Q8N2W9 Q8NFH3 Q8NFH4 Q8NFH5 Q8TEM1 Q8WUM0 Q92621 Q96HA1 Q99567 Q9BTX1 Q9BW27 Q9NRG9 Q9UKX7	AAAS ADRACALA C7orf14 CAIN CAN CG1 D3S1231E DDXBP1 KIAA0023 KIAA0095 KIAA0169 KIAA0197 KIAA0225 KIAA0618 KIAA0791 KIAA0906 MDM2 MP44 MRNP41 MYL NDC1 NPAP60L NUP107 NUP120 NUP121 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP358 NUP37 NUP42 NUP43 NUP50 NUP53 NUP54 NUP62 NUP75 NUP85 NUP88 NUP93 NUPL2 PCNT1 PIAS1 PIAS4 PIASG PML POM121 POM121A POM121C PP8675 RAE1 RANBP2 RFP RNF71 RNF76 SEC13 SEC13A SEC13L1 SEC13R SMT3C SMT3H3 SUMO1 TMEM48 TPR TRIM19 TRIM27 UBC9 UBCE9 UBE2I UBL1 VHL	Homo sapiens (human)

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