GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **2051 - 2075** of **2090** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism ▲	GlyTouCan ID
Telomere Extension By Telomerase	ATP-dependent DNA helicase PIF1 Adrenocortical dysplasia protein homolog Cyclin-A1 Cyclin-A2 Cyclin-dependent kinase 2 H/ACA ribonucleoprotein complex subunit 1 H/ACA ribonucleoprotein complex subunit 2 H/ACA ribonucleoprotein complex subunit 3 H/ACA ribonucleoprotein complex subunit DKC1 Protection of telomeres protein 1 Protein SHQ1 homolog Regulator of telomere elongation helicase 1 RuvB-like 1 RuvB-like 2 Serine/threonine-protein phosphatase 6 catalytic subunit Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A Serine/threonine-protein phosphatase 6 regulatory subunit 3 TERF1-interacting nuclear factor 2 Telomerase Cajal body protein 1 Telomerase reverse transcriptase Telomeric repeat-binding factor 1 Telomeric repeat-binding factor 2-interacting protein 1 Telomeric repeat-binding factor 2	O00743 O14746 O15084 O60832 P20248 P24941 P54274 P78396 Q15554 Q5H9R7 Q6PI26 Q96AP0 Q9BSI4 Q9BUR4 Q9H611 Q9NPE3 Q9NUX5 Q9NX24 Q9NY12 Q9NYB0 Q9NZ71 Q9Y230 Q9Y265	ACD ANKRD28 C11orf23 C15orf20 C20orf41 CCN1 CCNA CCNA1 CCNA2 CDK2 CDKN2 DKC1 DRIP5 EST2 GAR1 INO80H INO80J KIAA0379 KIAA1088 KIAA1558 NHL NHP2 NMP238 NOLA1 NOLA2 NOLA3 NOLA4 NOP10 PIF1 PIN2 PIP1 POT1 PP6R3 PPP6 PPP6C PPP6R3 PTOP RAP1 RTEL1 RUVBL1 RUVBL2 SAPL SAPS3 SHQ1 TCAB1 TCS1 TERF1 TERF2 TERF2IP TERT TIN2 TINF2 TINT1 TIP48 TIP49 TIP49A TIP49B TPP1 TRBF1 TRBF2 TRF TRF1 TRF2 TRT WDR79 WRAP53	Homo sapiens (human)
Inactivation, recovery and regulation of the phototransduction cascade	Calmodulin-1 Calmodulin-lysine N-methyltransferase Cyclic nucleotide-gated channel alpha-1 Cyclic nucleotide-gated channel beta-1 Glycylpeptide N-tetradecanoyltransferase 1 Glycylpeptide N-tetradecanoyltransferase 2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(t) subunit alpha-1 Guanylyl cyclase-activating protein 1 Guanylyl cyclase-activating protein 2 Guanylyl cyclase-activating protein 3 Methionine aminopeptidase 1 Methionine aminopeptidase 2 Protein farnesyltransferase subunit beta Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha Protein kinase C alpha type Protein kinase C theta type Recoverin Regulator of G-protein signaling 9-binding protein Retinal guanylyl cyclase 1 Retinal guanylyl cyclase 2 Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma Rhodopsin kinase GRK1 Rhodopsin kinase GRK7 Rhodopsin Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta S-arrestin Serine/threonine-protein phosphatase with EF-hands 1	O14829 O60551 O95843 P08100 P0DP23 P10523 P11488 P16499 P17252 P18545 P29973 P30419 P35243 P35913 P43080 P49354 P49356 P50579 P51841 P53582 P62873 P63211 Q02846 Q04759 Q14028 Q15835 Q6ZS82 Q7Z624 Q8WTQ7 Q9UMX6	C2orf34 C6orf131 CALM CALM1 CAM CAM1 CAMKMT CLNMT CNCG CNCG1 CNCG2 CNCG3L CNCG4 CNGA1 CNGB1 CORD6 FNTA FNTB GCAP GCAP1 GCAP2 GCAP3 GNAT1 GNATR GNB1 GNGT1 GPRK7 GRK1 GRK7 GUC1A4 GUC2D GUC2F GUCA1 GUCA1A GUCA1B GUCA1C GUCY2D GUCY2F KIAA0094 METAP1 METAP2 MNPEP NMT NMT1 NMT2 OPN2 P67EIF2 PDE6A PDE6B PDE6G PDEA PDEB PDEG PKCA PPEF PPEF1 PPP7C PRKACA PRKCA PRKCQ PRKCT R9AP RCNC2 RCV1 RCVRN RETGC RETGC1 RETGC2 RGS9BP RHO RHOK SAG	Homo sapiens (human)
HSP90 chaperone cycle for SHRs	Actin-related protein 10 Alpha-centractin Androgen receptor Cytoplasmic dynein 1 heavy chain 1 Cytoplasmic dynein 1 intermediate chain 1 Cytoplasmic dynein 1 intermediate chain 2 Cytoplasmic dynein 1 light intermediate chain 1 Cytoplasmic dynein 1 light intermediate chain 2 DnaJ homolog subfamily A member 1 DnaJ homolog subfamily A member 2 DnaJ homolog subfamily A member 4 DnaJ homolog subfamily B member 1 Dynactin subunit 1 Dynactin subunit 2 Dynactin subunit 3 Dynactin subunit 4 Dynactin subunit 5 Dynactin subunit 6 Dynein light chain 1, cytoplasmic Dynein light chain 2, cytoplasmic F-actin-capping protein subunit alpha-1 F-actin-capping protein subunit alpha-2 F-actin-capping protein subunit alpha-3 F-actin-capping protein subunit beta Glucocorticoid receptor Heat shock 70 kDa protein 1-like Heat shock 70 kDa protein 1A Heat shock 70 kDa protein 1B Heat shock cognate 71 kDa protein Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Heat shock-related 70 kDa protein 2 Mineralocorticoid receptor Peptidyl-prolyl cis-trans isomerase FKBP4 Peptidyl-prolyl cis-trans isomerase FKBP5 Progesterone receptor Prostaglandin E synthase 3 Stress-induced-phosphoprotein 1	O00399 O14576 O43237 O60884 O75935 P04150 P06401 P07900 P08235 P08238 P0DMV8 P0DMV9 P10275 P11142 P25685 P31689 P31948 P34931 P47755 P47756 P52907 P54652 P61163 P63167 Q02790 Q13409 Q13451 Q13561 Q14203 Q14204 Q15185 Q8WW22 Q96FJ2 Q96KX2 Q9BTE1 Q9NZ32 Q9UJW0 Q9Y6G9	ACTR10 ACTR11 ACTR1A AIG6 AR ARP10 ARP11 CAPAA3 CAPZA1 CAPZA2 CAPZA3 CAPZB CPR3 CTRN1 DCTN1 DCTN2 DCTN22 DCTN3 DCTN4 DCTN5 DCTN50 DCTN6 DHC1 DHTR DLC1 DLC2 DNAJ1 DNAJ2 DNAJA1 DNAJA2 DNAJA4 DNAJB1 DNCH1 DNCI1 DNCI2 DNCIC1 DNCIC2 DNCL DNCL1 DNCLC1 DNCLI1 DNCLI2 DNECL DYHC DYNC1H1 DYNC1I1 DYNC1I2 DYNC1LI1 DYNC1LI2 DYNLL1 DYNLL2 FKBP4 FKBP5 FKBP51 FKBP52 GRL GSG3 HDJ1 HDJ2 HDLC1 HIRIP4 HSC70 HSJ2 HSP72 HSP73 HSP90A HSP90AA1 HSP90AB1 HSP90B HSPA1 HSPA10 HSPA1A HSPA1B HSPA1L HSPA2 HSPA8 HSPC1 HSPC2 HSPC3 HSPCA HSPCB HSPF1 HSPF4 HSX70 KIAA0325 LIC2 MCR MLR NR3C1 NR3C2 NR3C3 NR3C4 P23 PGR PTGES3 STIP1 TEBP WS3	Homo sapiens (human)
Defensins	Beta-defensin (Fragment) Beta-defensin 103 Beta-defensin 104 Beta-defensin 105 Beta-defensin 106 Beta-defensin 107 Beta-defensin 108B Beta-defensin 110 Beta-defensin 112 Beta-defensin 113 Beta-defensin 114 Beta-defensin 115 Beta-defensin 116 Beta-defensin 119 Beta-defensin 121 Beta-defensin 123 Beta-defensin 124 Beta-defensin 125 Beta-defensin 126 Beta-defensin 127 Beta-defensin 128 Beta-defensin 129 Beta-defensin 130A Beta-defensin 130B Beta-defensin 131A Beta-defensin 132 Beta-defensin 133 Beta-defensin 134 Beta-defensin 135 Beta-defensin 1 Defensin alpha 4 Defensin alpha 5 Defensin beta 118 Defensin beta 136 Defensin beta 4A Defensin-6 Neutrophil defensin 1 Neutrophil defensin 3	O15263 P0DP73 P0DP74 P12838 P59665 P59666 P59861 P60022 P81534 Q01523 Q01524 Q30KP8 Q30KP9 Q30KQ1 Q30KQ3 Q30KQ4 Q30KQ5 Q30KQ6 Q30KQ7 Q30KQ8 Q30KQ9 Q4QY38 Q5J5C9 Q7Z7B7 Q7Z7B8 Q8IZN7 Q8N104 Q8N687 Q8N688 Q8N690 Q8NES8 Q8NET1 Q8NG35 Q8WTQ1 Q96PH6 Q9BYW3 Q9H1M3 Q9H1M4	BD1 BD3 BD5 BD6 C20orf63 C20orf73 C20orf8 C20orf87 DEF1 DEF3 DEF4 DEF5 DEF6 DEFA1 DEFA1B DEFA2 DEFA3 DEFA4 DEFA5 DEFA6 DEFB1 DEFB10 DEFB102 DEFB103 DEFB103A DEFB103B DEFB104 DEFB104A DEFB104B DEFB105 DEFB105A DEFB105B DEFB106 DEFB106A DEFB106B DEFB107 DEFB107A DEFB107B DEFB108 DEFB108B DEFB11 DEFB110 DEFB111 DEFB112 DEFB113 DEFB114 DEFB115 DEFB116 DEFB117 DEFB118 DEFB119 DEFB12 DEFB120 DEFB121 DEFB123 DEFB124 DEFB125 DEFB126 DEFB127 DEFB128 DEFB129 DEFB13 DEFB130 DEFB130A DEFB130B DEFB131 DEFB131A DEFB132 DEFB133 DEFB134 DEFB135 DEFB136 DEFB14 DEFB15 DEFB16 DEFB18 DEFB19 DEFB2 DEFB20 DEFB21 DEFB23 DEFB24 DEFB25 DEFB26 DEFB27 DEFB28 DEFB29 DEFB3 DEFB30 DEFB31 DEFB32 DEFB4 DEFB4A DEFB4B DEFB5 DEFB6 DEFB7 DEFB8 ESC42 HBD1 MRS	Homo sapiens (human)
Defective Mismatch Repair Associated With PMS2	DNA mismatch repair protein Mlh1 Mismatch repair endonuclease PMS2	P40692 P54278	COCA2 MLH1 PMS2 PMSL2	Homo sapiens (human)
Prefoldin mediated transfer of substrate to CCT/TriC	Actin, cytoplasmic 1 Prefoldin subunit 1 Prefoldin subunit 2 Prefoldin subunit 3 Prefoldin subunit 4 Prefoldin subunit 5 Prefoldin subunit 6 T-complex protein 1 subunit alpha T-complex protein 1 subunit beta T-complex protein 1 subunit delta T-complex protein 1 subunit epsilon T-complex protein 1 subunit eta T-complex protein 1 subunit gamma T-complex protein 1 subunit theta T-complex protein 1 subunit zeta-2 T-complex protein 1 subunit zeta Tubulin alpha-1A chain Tubulin alpha-1C chain Tubulin alpha-3C chain Tubulin alpha-3D chain Tubulin alpha-4A chain Tubulin beta-1 chain Tubulin beta-2A chain Tubulin beta-2B chain Tubulin beta-3 chain Tubulin beta-4A chain Tubulin beta-4B chain Tubulin beta-6 chain	O15212 O60925 P04350 P0DPH7 P0DPH8 P17987 P40227 P48643 P49368 P50990 P50991 P60709 P61758 P68366 P68371 P78371 Q13509 Q13885 Q71U36 Q92526 Q99471 Q99832 Q9BQE3 Q9BUF5 Q9BVA1 Q9H4B7 Q9NQP4 Q9UHV9	99D8.1 ACTB C21orf112 CCT1 CCT2 CCT3 CCT4 CCT5 CCT6 CCT6A CCT6B CCT7 CCT8 CCTA CCTB CCTD CCTE CCTG CCTH CCTQ CCTZ HKE2 KIAA0002 KIAA0098 MM1 NIP7-1 PFD1 PFD2 PFD4 PFD5 PFD6 PFDN1 PFDN2 PFDN3 PFDN4 PFDN5 PFDN6 SRB TCP1 TRIC5 TUBA1 TUBA1A TUBA1C TUBA2 TUBA3 TUBA3C TUBA3D TUBA4A TUBA6 TUBB1 TUBB2 TUBB2A TUBB2B TUBB2C TUBB3 TUBB4 TUBB4A TUBB4B TUBB5 TUBB6 VBP1	Homo sapiens (human)
Signaling by VEGF	Angio-associated migratory cell protein Vascular endothelial growth factor A, long form	P15692 Q13685	AAMP VEGF VEGFA	Homo sapiens (human)
Adenosine P1 receptors	Adenosine receptor A1 Adenosine receptor A2a Adenosine receptor A2b Adenosine receptor A3	P0DMS8 P29274 P29275 P30542	ADORA1 ADORA2 ADORA2A ADORA2B ADORA3	Homo sapiens (human)
Adenylate cyclase inhibitory pathway	Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Adenylate cyclase type 9 Guanine nucleotide-binding protein G(i) subunit alpha-1 Guanine nucleotide-binding protein G(i) subunit alpha-2 Guanine nucleotide-binding protein G(i) subunit alpha-3 Guanine nucleotide-binding protein G(olf) subunit alpha Guanine nucleotide-binding protein G(t) subunit alpha-3	A8MTJ3 O43306 O60266 O60503 O95622 P04899 P08754 P38405 P40145 P51828 P63096 Q08462 Q08828 Q8NFM4	ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 GNAI1 GNAI2 GNAI2B GNAI3 GNAL GNAT3 KIAA0037 KIAA0422 KIAA0511 KIAA0520 KIAA1060	Homo sapiens (human)
p75NTR recruits signalling complexes	Beta-nerve growth factor Inhibitor of nuclear factor kappa-B kinase subunit beta Interleukin-1 receptor-associated kinase 1 Myeloid differentiation primary response protein MyD88 Polyubiquitin-B Polyubiquitin-C Protein kinase C iota type Receptor-interacting serine/threonine-protein kinase 2 Sequestosome-1 TNF receptor-associated factor 6 Tumor necrosis factor receptor superfamily member 16 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O14920 O43353 P01138 P08138 P0CG47 P0CG48 P41743 P51617 P62979 P62987 Q13501 Q99836 Q9Y4K3	CARDIAK DXS1179E IKBKB IKKB IRAK IRAK1 MYD88 NGF NGFB NGFR ORCA OSIL PRKCI RICK RIP2 RIPK2 RNF85 RPS27A SQSTM1 TNFRSF16 TRAF6 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Homo sapiens (human)
Resistance of ERBB2 KD mutants to osimertinib	Erbin Heat shock protein HSP 90-alpha Hsp90 co-chaperone Cdc37 Receptor tyrosine-protein kinase erbB-2	P04626 P07900 Q16543 Q96RT1	CDC37 CDC37A ERBB2 ERBB2IP ERBIN HER2 HSP90A HSP90AA1 HSPC1 HSPCA KIAA1225 LAP2 MLN19 NEU NGL	Homo sapiens (human)
Branched-chain amino acid catabolism	2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial 3-hydroxyacyl-CoA dehydrogenase type-2 3-hydroxyisobutyrate dehydrogenase, mitochondrial 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial Acetyl-CoA acetyltransferase, mitochondrial Branched-chain alpha-ketoacid dehydrogenase kinase Branched-chain-amino-acid aminotransferase, cytosolic Branched-chain-amino-acid aminotransferase, mitochondrial Dihydrolipoyl dehydrogenase, mitochondrial Enoyl-CoA hydratase, mitochondrial Isobutyryl-CoA dehydrogenase, mitochondrial Isovaleryl-CoA dehydrogenase, mitochondrial Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial Methylglutaconyl-CoA hydratase, mitochondrial Methylmalonate-semialdehyde/malonate-semialdehyde dehydrogenase [acylating], mitochondrial Protein phosphatase Mn(2+)-dependent 1K Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial Solute carrier family 25 member 44	O14874 O15382 P09622 P11182 P12694 P21953 P24752 P26440 P30084 P31937 P45954 P54687 Q02252 Q13825 Q6NVY1 Q8N3J5 Q96H78 Q96RQ3 Q99714 Q9HCC0 Q9UKU7	ACAD8 ACADSB ACAT ACAT1 ALDH6A1 ARC42 AUH BCAT1 BCAT2 BCATE2 BCATM BCKDHA BCKDHB BCKDHE2 BCKDK BCT1 BCT2 DBT DLD ECA39 ECA40 ECHS1 ERAB GCSL HADH2 HIBADH HIBCH HSD17B10 IBD IVD KIAA0446 LAD MAT MCCA MCCB MCCC1 MCCC2 MMSDH MRPP2 PHE3 PP2CM PPM1K SCHAD SDR5C1 SLC25A44 XH98G2	Homo sapiens (human)
Phosphorylation of CD3 and TCR zeta chains	HLA class II histocompatibility antigen, DP alpha 1 chain HLA class II histocompatibility antigen, DP beta 1 chain HLA class II histocompatibility antigen, DQ alpha 1 chain HLA class II histocompatibility antigen, DQ alpha 2 chain HLA class II histocompatibility antigen, DQ beta 1 chain HLA class II histocompatibility antigen, DQ beta 2 chain HLA class II histocompatibility antigen, DR alpha chain HLA class II histocompatibility antigen, DR beta 3 chain HLA class II histocompatibility antigen, DR beta 4 chain HLA class II histocompatibility antigen, DR beta 5 chain HLA class II histocompatibility antigen, DRB1 beta chain Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 Receptor-type tyrosine-protein phosphatase C Receptor-type tyrosine-protein phosphatase eta T cell receptor alpha chain constant T cell receptor alpha variable 19 T cell receptor alpha variable 29/delta variable 5 T cell receptor alpha variable 8-4 T cell receptor beta constant 1 T cell receptor beta variable 12-3 T cell receptor beta variable 7-9 T-cell surface glycoprotein CD3 delta chain T-cell surface glycoprotein CD3 epsilon chain T-cell surface glycoprotein CD3 gamma chain T-cell surface glycoprotein CD4 Tyrosine-protein kinase CSK Tyrosine-protein kinase Lck Tyrosine-protein phosphatase non-receptor type 22	A0A0A6YYK7 P01730 P01733 P01737 P01848 P01850 P01903 P01906 P01909 P01911 P01920 P04234 P04435 P04437 P04440 P05538 P06239 P07766 P08575 P09693 P13762 P20036 P41240 P79483 Q12913 Q30154 Q9NWQ8 Q9Y2R2	CBP CD3D CD3E CD3G CD4 CD45 CSK DEP1 HLA-DP1A HLA-DP1B HLA-DPA1 HLA-DPB1 HLA-DQA1 HLA-DQA2 HLA-DQB HLA-DQB1 HLA-DQB2 HLA-DRA HLA-DRA1 HLA-DRB1 HLA-DRB3 HLA-DRB4 HLA-DRB5 HLA-DXA HLA-DXB HLASB LCK PAG PAG1 PTPN22 PTPN8 PTPRC PTPRJ T3D T3E T3G TCRA TCRBV12S3 TCRBV8S1 TRAC TRAV19 TRAV29DV5 TRAV8-4 TRBC1 TRBV12-3 TRBV7-9	Homo sapiens (human)
Transcriptional regulation of testis differentiation	Desert hedgehog protein Doublesex- and mab-3-related transcription factor 1 Fibroblast growth factor 9 Muellerian-inhibiting factor Prostaglandin-H2 D-isomerase Sex-determining region Y protein Steroidogenic factor 1 Transcription factor GATA-4 Transcription factor SOX-9 Wilms tumor protein Zinc finger protein ZFPM2	O43323 P03971 P19544 P31371 P41222 P43694 P48436 Q05066 Q13285 Q8WW38 Q9Y5R6	AD4BP AMH DHH DMRT1 DMT1 FGF9 FOG2 FTZF1 GATA4 MIF NR5A1 PDS PTGDS SF1 SOX9 SRY TDF WT1 ZFPM2 ZNF89B	Homo sapiens (human)
TGFBR2 Kinase Domain Mutants in Cancer	TGF-beta receptor type-1 TGF-beta receptor type-2 Transforming growth factor beta-1 proprotein	P01137 P36897 P37173	ALK5 SKR4 TGFB TGFB1 TGFBR1 TGFBR2	Homo sapiens (human)
Maturation of spike protein	Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase Calnexin Glucosidase 2 subunit beta Mannosyl-oligosaccharide glucosidase Neutral alpha-glucosidase AB Spike glycoprotein	P14314 P26572 P27824 P59594 Q13724 Q14697	CANX G19P1 G2AN GANAB GCS1 GGNT1 GLCT1 GLYT1 KIAA0088 MGAT MGAT1 MOGS PRKCSH S	Homo sapiens (human)	G71142DF
Vif-mediated degradation of APOBEC3G	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Cullin-5 E3 ubiquitin-protein ligase RBX1 Elongin-B Elongin-C Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Virion infectivity factor	A5LHX3 O00231 O00232 O00233 O00487 O14818 O43242 O75832 P0CG47 P0CG48 P17980 P20618 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P35998 P40306 P43686 P48556 P49720 P49721 P51665 P55036 P60896 P60900 P61289 P62191 P62195 P62333 P62877 P62979 P62987 P69723 Q06323 Q13200 Q14997 Q15008 Q15369 Q15370 Q16401 Q8TAA3 Q92530 Q93034 Q99436 Q99460 Q9UL46 Q9UNM6	C7orf76 CUL5 DSS1 ELOB ELOC HC2 HC3 HC8 HC9 HSPC IFI5111 KIAA0072 KIAA0077 KIAA0107 LMP10 LMP2 LMP7 LMPX LMPY MB1 MCB1 MECL1 MIP224 MOV34L MSS1 NU PFAAP4 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 RBX1 RING10 RING12 RNF75 ROC1 RPS27A SEM1 SHFDG1 SHFM1 SUG1 SUG2 TBP1 TBP7 TCEB1 TCEB2 TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 VACM1 X Y Y2 Z vif	Homo sapiens (human)
Physiological factors	Atrial natriuretic peptide receptor 1 Atrial natriuretic peptide receptor 2 Atrial natriuretic peptide-converting enzyme C-type natriuretic peptide Histone acetyltransferase KAT2B Homeobox protein Nkx-2.5 Homeodomain-interacting protein kinase 1 Homeodomain-interacting protein kinase 2 Liver carboxylesterase 1 Natriuretic peptides A Neprilysin T-box transcription factor TBX5 Transcription factor GATA-4 WW domain-containing transcription regulator protein 1	P01160 P08473 P16066 P20594 P23141 P23582 P43694 P52952 Q86Z02 Q92831 Q99593 Q9GZV5 Q9H2X6 Q9Y5Q5	ANP ANPRA ANPRB CES1 CES2 CNP2 CORIN CRN CSX EPN GATA4 HIPK1 HIPK2 KAT2B KIAA0630 MME MYAK NBAK2 NKX2-5 NKX2.5 NKX2E NPPA NPPC NPR1 NPR2 PCAF PND SES1 TAZ TBX5 TMPRSS10 WWTR1	Homo sapiens (human)
Interconversion of 2-oxoglutarate and 2-hydroxyglutarate	D-2-hydroxyglutarate dehydrogenase, mitochondrial Hydroxyacid-oxoacid transhydrogenase, mitochondrial L-2-hydroxyglutarate dehydrogenase, mitochondrial	Q8IWW8 Q8N465 Q9H9P8	ADHFE1 C14orf160 D2HGD D2HGDH L2HGDH	Homo sapiens (human)
FGFR2c ligand binding and activation	Fibroblast growth factor 16 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 4 Fibroblast growth factor 6 Fibroblast growth factor 9	O43320 O76093 P05230 P08620 P09038 P10767 P31371 Q9GZV9 Q9NP95	FGF1 FGF16 FGF18 FGF2 FGF20 FGF23 FGF4 FGF6 FGF9 FGFA FGFB HST HST2 HSTF1 HSTF2 HYPF KS3	Homo sapiens (human)
Translocation of SLC2A4 (GLUT4) to the plasma membrane	14-3-3 protein beta/alpha 14-3-3 protein epsilon 14-3-3 protein eta 14-3-3 protein gamma 14-3-3 protein sigma 14-3-3 protein theta 14-3-3 protein zeta/delta 5'-AMP-activated protein kinase catalytic subunit alpha-2 5'-AMP-activated protein kinase subunit beta-1 5'-AMP-activated protein kinase subunit beta-2 5'-AMP-activated protein kinase subunit gamma-1 5'-AMP-activated protein kinase subunit gamma-2 5'-AMP-activated protein kinase subunit gamma-3 C2 domain-containing protein 5 Calmodulin-1 Exocyst complex component 1 Exocyst complex component 2 Exocyst complex component 3 Exocyst complex component 4 Exocyst complex component 5 Exocyst complex component 6 Exocyst complex component 7 Exocyst complex component 8 Kinesin-associated protein 3 Kinesin-like protein KIF3A Kinesin-like protein KIF3B Leucyl-cystinyl aminopeptidase Myosin-9 RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase Ral GTPase-activating protein subunit alpha-2 Ral GTPase-activating protein subunit beta Ras-related C3 botulinum toxin substrate 1 Ras-related protein Rab-10 Ras-related protein Rab-11A Ras-related protein Rab-13 Ras-related protein Rab-14 Ras-related protein Rab-4A Ras-related protein Rab-8A Ras-related protein Ral-A Rho-related GTP-binding protein RhoQ Solute carrier family 2, facilitated glucose transporter member 4 Synaptosomal-associated protein 23 Syntaxin-4 Syntaxin-binding protein 3 TBC1 domain family member 1 TBC1 domain family member 4 Tether containing UBX domain for GLUT4 Unconventional myosin-Ic Unconventional myosin-Va Vesicle-associated membrane protein 2	O00159 O00161 O00186 O00471 O15066 O43741 O60343 O60645 P0DP23 P11233 P14672 P17081 P20338 P27348 P31749 P31751 P31946 P31947 P35579 P51153 P54619 P54646 P61006 P61026 P61106 P61981 P62258 P62491 P63000 P63027 P63104 Q04917 Q12846 Q2PPJ7 Q86TI0 Q86X10 Q86YS7 Q8IYI6 Q8TAG9 Q92845 Q96A65 Q96KP1 Q9BZE9 Q9NV70 Q9UGI9 Q9UGJ0 Q9UIQ6 Q9UPT5 Q9Y478 Q9Y496 Q9Y4I1	AKT1 AKT2 AMPK AMPK2 AMPKG3 ARHQ AS160 ASPL ASPSCR1 C20orf74 C2CD5 CALM CALM1 CAM CAM1 CDP138 EXO70 EXOC1 EXOC2 EXOC3 EXOC4 EXOC5 EXOC6 EXOC7 EXOC8 GLUT4 HME1 KIAA0359 KIAA0528 KIAA0603 KIAA1067 KIAA1108 KIAA1219 KIAA1272 KIAA1699 KIF3 KIF3A KIF3AP KIF3B KIFAP3 LNPEP MEL MYH12 MYH9 MYO1C MYO5A OTASE PKB PRKAA2 PRKAB1 PRKAB2 PRKAG1 PRKAG2 PRKAG3 RAB10 RAB11 RAB11A RAB13 RAB14 RAB4 RAB4A RAB8 RAB8A RAC RAC1 RAL RALA RALGAPA2 RALGAPB RASL7A RCC17 RHOQ SEC10 SEC10L1 SEC15A SEC15L SEC15L1 SEC3 SEC3L1 SEC5 SEC5L1 SEC6 SEC6L1 SEC8 SEC8L1 SFN SLC2A4 SMAP SNAP23 STX4 STX4A STXBP3 SYB2 TBC1D1 TBC1D4 TC10 TC25 TUG UBXD9 UBXN9 VAMP2 YWHA1 YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ	Homo sapiens (human)
Defective ALG1 causes CDG-1k	Chitobiosyldiphosphodolichol beta-mannosyltransferase	Q9BT22	ALG1 HMAT1 HMT1	Homo sapiens (human)
Neurotransmitter receptors and postsynaptic signal transmission	5-hydroxytryptamine receptor 3A 5-hydroxytryptamine receptor 3B 5-hydroxytryptamine receptor 3C 5-hydroxytryptamine receptor 3D 5-hydroxytryptamine receptor 3E Glycine receptor subunit alpha-1 Glycine receptor subunit alpha-2 Glycine receptor subunit alpha-3 Glycine receptor subunit beta Neurobeachin	A5X5Y0 O75311 O95264 P23415 P23416 P46098 P48167 Q70Z44 Q8NFP9 Q8WXA8	5HT3R BCL8B GLRA1 GLRA2 GLRA3 GLRB HTR3 HTR3A HTR3B HTR3C HTR3D HTR3E KIAA1544 LYST2 NBEA	Homo sapiens (human)
Variant SLC6A20 contributes towards hyperglycinuria (HG) and iminoglycinuria (IG)	Sodium- and chloride-dependent transporter XTRP3	Q9NP91	SIT1 SLC6A20 XT3 XTRP3	Homo sapiens (human)
Maturation of protein E	Envelope small membrane protein Polyubiquitin-B Polyubiquitin-C Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	P0CG47 P0CG48 P0DTC4 P62979 P62987	E RPS27A UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Homo sapiens (human)

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