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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
systemic lupus erythematosus
Summary
- Synonym
-
- Lupus Erythematosus, systemic
- SLE - Lupus Erythematosus, systemic
- disseminated lupus erythematosus
- Definition
- A lupus erythematosus that is an inflammation of connective tissue marked by skin rashes, joint pain and swelling, inflammation of the kidneys and inflammation of the tissue surrounding the heart.
- Super Class
- connective tissue disease lupus erythematosus
External Links
- Disease Ontology
- DOID:9074
- Mondo Disease Ontology
- MeSH
- UMLS
- NCI Thesaurus
- ORDO
- OMIM
- GARD
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 177 | AGER | advanced glycosylation end-product specific receptor | |
| 335 | APOA1 | apolipoprotein A1 | |
| 355 | FAS | Fas cell surface death receptor | |
| 639 | PRDM1 | PR/SET domain 1 | |
| 712 | C1QA | complement C1q A chain | |
| 717 | C2 | complement C2 | |
| 718 | C3 | complement C3 | |
| 720 | C4A | complement C4A (Chido/Rodgers blood group) | |
| 721 | C4B | complement C4B (Chido/Rodgers blood group) | |
| 831 | CAST | calpastatin |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 18173 | Slc11a1 | solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 | |
| 18566 | Pdcd1 | programmed cell death 1 | |
| 18646 | Prf1 | perforin 1 (pore forming protein) | |
| 18654 | Pgf | placental growth factor | |
| 19016 | Pparg | peroxisome proliferator activated receptor gamma | |
| 19264 | Ptprc | protein tyrosine phosphatase receptor type C | |
| 20181 | Rxra | retinoid X receptor alpha | |
| 20296 | Ccl2 | C-C motif chemokine ligand 2 | |
| 20343 | Sell | selectin, lymphocyte | |
| 20390 | Sftpd | surfactant associated protein D |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 24232 | C3 | complement C3 | |
| 24233 | C4a | complement C4A | |
| 24296 | Cyp1a1 | cytochrome P450, family 1, subfamily a, polypeptide 1 | |
| 24699 | Ptprc | protein tyrosine phosphatase, receptor type, C | |
| 24770 | Ccl2 | C-C motif chemokine ligand 2 | |
| 24787 | Sod2 | superoxide dismutase 2 | |
| 24835 | Tnf | tumor necrosis factor | |
| 24854 | Clu | clusterin | |
| 25149 | Esr2 | estrogen receptor 2 | |
| 25325 | Il10 | interleukin 10 |
| Gene ID | Gene Symbol | Description | Source | Organism |
|---|---|---|---|---|
| 373644 | ldlr.S | low density lipoprotein receptor S homeolog | Xenopus laevis (African clawed frog) | |
| 397757 | ldlr.L | low density lipoprotein receptor L homeolog | Xenopus laevis (African clawed frog) | |
| 734211 | epor.L | erythropoietin receptor L homeolog | Xenopus laevis (African clawed frog) |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 174116 | gldi-2 | EGF-like domain-containing protein | |
| 177044 | smf-3 | NRAMP-like transporter smf-3 | |
| 178748 | zmp-3 | Matrix metalloproteinase-C | |
| 179105 | F09G2.8 | putative phospholipase D F09G2.8 | |
| 179632 | aman-2 | Alpha-mannosidase | |
| 180836 | W01C8.5 | DM13 domain-containing protein | |
| 180939 | smf-1 | NRAMP-like transporter smf-1 | |
| 191766 | smf-2 | NRAMP-like transporter smf-2 | |
| 3565419 | clr-1 | Receptor-type tyrosine-protein phosphatase;protein-tyrosine-phosphatase |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0002039 | Anorexia |
| HP:0001250 | Seizure |
| HP:0012378 | Fatigue |
| HP:0000716 | Depression |
| HP:0003493 | Antinuclear antibody positivity |
| HP:0001873 | Thrombocytopenia |
| HP:0000155 | Oral ulcer |
| HP:0001882 | Leukopenia |
| HP:0007417 | Discoid lupus rash |
| HP:0000822 | Hypertension |
