Signal transduction by L1
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- CAML1
- CK2A1
- CK2A2
- CK2N
- CSNK2A1
- CSNK2A2
- CSNK2B
- EGFR
- ERBB
- ERBB1
- ERK1
- ERK2
- FNRA
- FNRB
- G5A
- GP2B
- GP3A
- HER1
- ITGA2B
- ITGA5
- ITGA9
- ITGAB
- ITGAV
- ITGB1
- ITGB3
- L1CAM
- MAP2K1
- MAP2K2
- MAPK1
- MAPK3
- MDF2
- MEK1
- MEK2
- MIC5
- MKK2
- MSK12
- MSK8
- NCAM
- NCAM1
- NRP
- NRP1
- PAK1
- PRKM1
- PRKM2
- PRKM3
- PRKMK1
- PRKMK2
- RAC1
- TC25
- VAV2
- VEGF165R
- VNRA
- VTNR
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TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway
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- API1
- API2
- APO3L
- BAFF
- BAFFR
- BIRC2
- BIRC3
- BLYS
- BR3
- CAP-1
- CD40L
- CD40LG
- CRAF1
- D12S370
- DR3LG
- FN14
- HVEML
- LIGHT
- LTA
- LTB
- LTBR
- MAP3K14
- MIHB
- MIHC
- NIK
- OPGL
- RANK
- RANKL
- RNF48
- RNF49
- TALL1
- TNFB
- TNFC
- TNFCR
- TNFR3
- TNFRSF11A
- TNFRSF12A
- TNFRSF13C
- TNFRSF3
- TNFSF1
- TNFSF11
- TNFSF12
- TNFSF13B
- TNFSF14
- TNFSF20
- TNFSF3
- TNFSF5
- TRAF2
- TRAF3
- TRAFAMN
- TRANCE
- TRAP
- TRAP3
- ZTNF4
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FOXO-mediated transcription of cell cycle genes
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- AFX
- AFX1
- BTG1
- CAP20
- CAV
- CAV1
- CCNG2
- CDKN1
- CDKN1A
- CDKN1B
- CIP1
- DDIT1
- DPC4
- EZF
- FKH2
- FKHL1
- FKHL2
- FKHL3
- FKHL4
- FKHR
- FKHRL1
- FOXG1
- FOXG1A
- FOXG1B
- FOXG1C
- FOXO1
- FOXO1A
- FOXO3
- FOXO3A
- FOXO4
- GADD45
- GADD45A
- GDF8
- GKLF
- KIP1
- KLF4
- MADH2
- MADH3
- MADH4
- MADR2
- MDA6
- MLLT7
- MSTN
- PCBP4
- PIC1
- RB2
- RBL2
- SDI1
- SMAD2
- SMAD3
- SMAD4
- WAF1
- p27
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Dopamine Neurotransmitter Release Cycle
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- APBA1
- BZRAP1
- CASK
- CPLX1
- KIAA0340
- KIAA0612
- KIAA0654
- KIAA0897
- LIN2
- LIN7A
- LIN7B
- LIN7C
- LIP1
- MALS1
- MALS2
- MALS3
- MINT1
- PPFIA1
- PPFIA2
- PPFIA3
- PPFIA4
- RAB3A
- RAB3IP2
- RBP1
- RIM1
- RIMBP1
- RIMS1
- SLC18A2
- SNAP
- SNAP25
- STX1
- STX1A
- SVMT
- SVP65
- SYB2
- SYN1
- SYN2
- SYN3
- SYT
- SYT1
- TSPOAP1
- UNC13
- UNC13B
- VAMP2
- VELI1
- VELI2
- VELI3
- VMAT2
- X11
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Serotonin Neurotransmitter Release Cycle
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- BZRAP1
- CPLX1
- KIAA0340
- KIAA0612
- KIAA0654
- KIAA0897
- LIP1
- PPFIA1
- PPFIA2
- PPFIA3
- PPFIA4
- RAB3A
- RAB3IP2
- RBP1
- RIM1
- RIMBP1
- RIMS1
- SLC18A2
- SNAP
- SNAP25
- STX1
- STX1A
- SVMT
- SVP65
- SYB2
- SYN1
- SYN2
- SYN3
- SYT
- SYT1
- TSPOAP1
- UNC13
- UNC13B
- VAMP2
- VMAT2
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Norepinephrine Neurotransmitter Release Cycle
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- BZRAP1
- CPLX1
- KIAA0340
- KIAA0612
- KIAA0654
- KIAA0897
- LIP1
- MAOA
- OCT1
- OCT2
- PPFIA1
- PPFIA2
- PPFIA3
- PPFIA4
- RAB3A
- RAB3IP2
- RBP1
- RIM1
- RIMBP1
- RIMS1
- SLC18A2
- SLC22A1
- SLC22A2
- SNAP
- SNAP25
- STX1
- STX1A
- SVMT
- SVP65
- SYB2
- SYT
- SYT1
- TSPOAP1
- UNC13
- UNC13B
- VAMP2
- VMAT2
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Acetylcholine Neurotransmitter Release Cycle
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- BZRAP1
- CHAT
- CHT1
- CPLX1
- KIAA0340
- KIAA0612
- KIAA0654
- KIAA0897
- LIP1
- PPFIA1
- PPFIA2
- PPFIA3
- PPFIA4
- RAB3A
- RAB3IP2
- RBP1
- RIM1
- RIMBP1
- RIMS1
- SLC18A3
- SLC5A7
- SNAP
- SNAP25
- STX1
- STX1A
- SVP65
- SYB2
- SYT
- SYT1
- TSPOAP1
- UNC13
- UNC13B
- VACHT
- VAMP2
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Cytosolic sensors of pathogen-associated DNA
|
- DNA-dependent protein kinase catalytic subunit
- DNA-directed RNA polymerase III subunit RPC10
- DNA-directed RNA polymerase III subunit RPC1
- DNA-directed RNA polymerase III subunit RPC2
- DNA-directed RNA polymerase III subunit RPC3
- DNA-directed RNA polymerase III subunit RPC4
- DNA-directed RNA polymerase III subunit RPC5
- DNA-directed RNA polymerase III subunit RPC6
- DNA-directed RNA polymerase III subunit RPC7-like
- DNA-directed RNA polymerase III subunit RPC7
- DNA-directed RNA polymerase III subunit RPC8
- DNA-directed RNA polymerase III subunit RPC9
- DNA-directed RNA polymerases I and III subunit RPAC1
- DNA-directed RNA polymerases I, II, and III subunit RPABC1
- DNA-directed RNA polymerases I, II, and III subunit RPABC2
- DNA-directed RNA polymerases I, II, and III subunit RPABC3
- DNA-directed RNA polymerases I, II, and III subunit RPABC4
- DNA-directed RNA polymerases I, II, and III subunit RPABC5
- Double-strand break repair protein MRE11
- Interferon-inducible protein AIM2
- Protein POLR1D, isoform 2
- X-ray repair cross-complementing protein 5
- X-ray repair cross-complementing protein 6
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- AIM2
- BN51
- BN51T
- CRCP
- G22P1
- G22P2
- HNGS1
- HYRC
- HYRC1
- KIAA1452
- KIAA1665
- MRE11
- MRE11A
- POLR1C
- POLR1D
- POLR1E
- POLR2E
- POLR2F
- POLR2H
- POLR2K
- POLR2L
- POLR3A
- POLR3B
- POLR3C
- POLR3D
- POLR3E
- POLR3F
- POLR3G
- POLR3GL
- POLR3H
- POLR3K
- POLRF
- PRKDC
- RPC11
- RPC8
- XRCC5
- XRCC6
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RNA Polymerase III Chain Elongation
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- DNA-directed RNA polymerase III subunit RPC10
- DNA-directed RNA polymerase III subunit RPC1
- DNA-directed RNA polymerase III subunit RPC2
- DNA-directed RNA polymerase III subunit RPC3
- DNA-directed RNA polymerase III subunit RPC4
- DNA-directed RNA polymerase III subunit RPC5
- DNA-directed RNA polymerase III subunit RPC6
- DNA-directed RNA polymerase III subunit RPC7-like
- DNA-directed RNA polymerase III subunit RPC7
- DNA-directed RNA polymerase III subunit RPC8
- DNA-directed RNA polymerase III subunit RPC9
- DNA-directed RNA polymerases I and III subunit RPAC1
- DNA-directed RNA polymerases I, II, and III subunit RPABC1
- DNA-directed RNA polymerases I, II, and III subunit RPABC2
- DNA-directed RNA polymerases I, II, and III subunit RPABC3
- DNA-directed RNA polymerases I, II, and III subunit RPABC4
- DNA-directed RNA polymerases I, II, and III subunit RPABC5
- Protein POLR1D, isoform 2
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- BN51
- BN51T
- CRCP
- KIAA1452
- KIAA1665
- POLR1C
- POLR1D
- POLR1E
- POLR2E
- POLR2F
- POLR2H
- POLR2K
- POLR2L
- POLR3A
- POLR3B
- POLR3C
- POLR3D
- POLR3E
- POLR3F
- POLR3G
- POLR3GL
- POLR3H
- POLR3K
- POLRF
- RPC11
- RPC8
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Amine ligand-binding receptors
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- GPR102
- GPR143
- GPR57
- GPR58
- OA1
- PNR
- TA1
- TA3
- TA4
- TA5
- TAAR1
- TAAR2
- TAAR3
- TAAR3P
- TAAR5
- TAAR6
- TAAR8
- TAAR9
- TAR1
- TAR3
- TAR4
- TAR5
- TRAR1
- TRAR3
- TRAR4
- TRAR5
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RAF activation
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- ARAF
- ARAF1
- BRAF
- BRAF1
- BRAP
- CALM
- CALM1
- CAM
- CAM1
- CAM2
- CAMK
- CAMK-II
- CAMK2
- CAMK2A
- CAMK2B
- CAMK2D
- CAMK2G
- CAMKA
- CAMKB
- CAMKD
- CAMKG
- CTAK1
- EMK2
- HRAS
- HRAS1
- JAK2
- KIAA0044
- KIAA0862
- KIAA0968
- KSR
- KSR1
- MAP2K1
- MAP2K2
- MAP3K11
- MARK3
- MEK1
- MEK2
- MKK2
- MLK3
- MRAS
- NRAS
- PHB
- PHB1
- PKS
- PKS2
- PPP1CB
- PPP1CC
- PPP2CA
- PPP2CB
- PPP2R1A
- PPP2R1B
- PPP2R5A
- PPP2R5B
- PPP2R5C
- PPP2R5D
- PPP2R5E
- PRKMK1
- PRKMK2
- PTK1
- RAF
- RAF1
- RAFB1
- RNF52
- RRAS3
- SHOC2
- SPRK
- SRC
- SRC1
- YWHAB
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SHOC2 M1731 mutant abolishes MRAS complex function
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- ARAF
- ARAF1
- BRAF
- BRAF1
- KIAA0862
- MRAS
- PKS
- PKS2
- PPP1CB
- PPP1CC
- RAF
- RAF1
- RAFB1
- RRAS3
- SHOC2
- YWHAB
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Gain-of-function MRAS complexes activate RAF signaling
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- ARAF
- ARAF1
- BRAF
- BRAF1
- KIAA0862
- MRAS
- PKS
- PKS2
- PPP1CB
- PPP1CC
- RAF
- RAF1
- RAFB1
- RRAS3
- SHOC2
- YWHAB
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GABA synthesis, release, reuptake and degradation
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- CLN4
- CPLX1
- DNAJC5
- GAD
- GAD1
- GAD2
- GAD65
- GAD67
- HSC70
- HSP73
- HSPA10
- HSPA8
- KIAA0340
- RAB3A
- RAB3IP2
- RIM1
- RIMS1
- SLC32A1
- SNAP
- SNAP25
- STX1
- STX1A
- SVP65
- SYB2
- SYT
- SYT1
- VAMP2
- VGAT
- VIAAT
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Ras activation upon Ca2+ influx through NMDA receptor
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- ACTN2
- CALM
- CALM1
- CAM
- CAM1
- CAM2
- CAMK
- CAMK-II
- CAMK2
- CAMK2A
- CAMK2B
- CAMK2D
- CAMK2G
- CAMKA
- CAMKB
- CAMKD
- CAMKG
- CDC25
- DLG1
- DLG2
- DLG3
- DLG4
- GNRP
- GRF1
- GRF2
- GRIN1
- GRIN2B
- GRIN2D
- GluN2D
- HRAS
- HRAS1
- KIAA0968
- KIAA1232
- KIAA1365
- LAP1
- LRRC7
- NEFL
- NF68
- NFL
- NMDAR1
- NMDAR2B
- NMDAR2D
- NRAS
- PSD95
- RASGRF1
- RASGRF2
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Inactivation, recovery and regulation of the phototransduction cascade
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- C2orf34
- C6orf131
- CALM
- CALM1
- CAM
- CAM1
- CAMKMT
- CLNMT
- CNCG
- CNCG1
- CNCG2
- CNCG3L
- CNCG4
- CNGA1
- CNGB1
- CORD6
- FNTA
- FNTB
- GCAP
- GCAP1
- GCAP2
- GCAP3
- GNAT1
- GNATR
- GNB1
- GNGT1
- GPRK7
- GRK1
- GRK7
- GUC1A4
- GUC2D
- GUC2F
- GUCA1
- GUCA1A
- GUCA1B
- GUCA1C
- GUCY2D
- GUCY2F
- KIAA0094
- METAP1
- METAP2
- MNPEP
- NMT
- NMT1
- NMT2
- OPN2
- P67EIF2
- PDE6A
- PDE6B
- PDE6G
- PDEA
- PDEB
- PDEG
- PKCA
- PPEF
- PPEF1
- PPP7C
- PRKACA
- PRKCA
- PRKCQ
- PRKCT
- R9AP
- RCNC2
- RCV1
- RCVRN
- RETGC
- RETGC1
- RETGC2
- RGS9BP
- RHO
- RHOK
- SAG
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Alpha-oxidation of phytanate
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|
- ACSVL1
- FACVL1
- FATP2
- HACL1
- HPCL
- HPCL2
- PAHX
- PECR
- PHYH
- PHYH2
- PMP34
- SDR29C1
- SLC25A17
- SLC27A2
- VLACS
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Defective OPLAH causes OPLAHD
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Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion
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- FFAR1
- GA11
- GAQ
- GNA11
- GNA14
- GNA15
- GNA16
- GNAQ
- GPR40
- KIAA0581
- PLCB1
- PLCB2
- PLCB3
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Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
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|
- ADCP2
- AN2
- CD26
- DPP4
- FFAR1
- GATA4
- GIP
- GPR119
- GPR40
- ISL1
- KIAA0102
- NEC1
- PAX6
- PCSK1
- SEC11A
- SEC11C
- SEC11L1
- SEC11L3
- SPC12
- SPC18
- SPC21
- SPC22
- SPC25
- SPCS1
- SPCS2
- SPCS3
- SPCS4A
- SPCS4C
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NFE2L2 regulating anti-oxidant/detoxification enzymes
|
|
|
- ATF4
- BACH1
- C20orf139
- CBP
- CREB2
- CREBBP
- DIA4
- EP300
- GCLC
- GCLM
- GLCL
- GLCLC
- GLCLR
- GRIM12
- GSTA1
- GSTA3
- HMOX1
- HO
- HO1
- KDRF
- MAFK
- NFE2L2
- NMOR1
- NQO1
- NRF2
- P300
- PAGA
- PAGB
- PRDX1
- SLC7A11
- SOD3
- SRX
- SRX1
- SRXN1
- TDPX2
- TRDX
- TRX
- TRX1
- TXN
- TXNRD1
- TXREB
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Regulation of HMOX1 expression and activity
|
|
|
- BACH1
- H13
- HM13
- HMOX1
- HO
- HO1
- IMP1
- MAFK
- NFE2L2
- NRF2
- PSL3
- SPP
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Regulation of BACH1 activity
|
|
|
- BACH1
- CUL1
- EMC19
- FBL17
- FBX13
- FBXL1
- FBXL17
- FBXO13
- MAFK
- OCP2
- RBX1
- RNF75
- ROC1
- RPS27A
- SKP1
- SKP1A
- SKP2
- TCEB1L
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
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Branched-chain amino acid catabolism
|
- 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial
- 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial
- 3-hydroxyacyl-CoA dehydrogenase type-2
- 3-hydroxyisobutyrate dehydrogenase, mitochondrial
- 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial
- Acetyl-CoA acetyltransferase, mitochondrial
- Branched-chain alpha-ketoacid dehydrogenase kinase
- Branched-chain-amino-acid aminotransferase, cytosolic
- Branched-chain-amino-acid aminotransferase, mitochondrial
- Dihydrolipoyl dehydrogenase, mitochondrial
- Enoyl-CoA hydratase, mitochondrial
- Isobutyryl-CoA dehydrogenase, mitochondrial
- Isovaleryl-CoA dehydrogenase, mitochondrial
- Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial
- Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial
- Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial
- Methylglutaconyl-CoA hydratase, mitochondrial
- Methylmalonate-semialdehyde/malonate-semialdehyde dehydrogenase [acylating], mitochondrial
- Protein phosphatase Mn(2+)-dependent 1K
- Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial
- Solute carrier family 25 member 44
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|
- ACAD8
- ACADSB
- ACAT
- ACAT1
- ALDH6A1
- ARC42
- AUH
- BCAT1
- BCAT2
- BCATE2
- BCATM
- BCKDHA
- BCKDHB
- BCKDHE2
- BCKDK
- BCT1
- BCT2
- DBT
- DLD
- ECA39
- ECA40
- ECHS1
- ERAB
- GCSL
- HADH2
- HIBADH
- HIBCH
- HSD17B10
- IBD
- IVD
- KIAA0446
- LAD
- MAT
- MCCA
- MCCB
- MCCC1
- MCCC2
- MMSDH
- MRPP2
- PHE3
- PP2CM
- PPM1K
- SCHAD
- SDR5C1
- SLC25A44
- XH98G2
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|
Glutathione conjugation
|
|
|
- AKR1A1
- ALDR1
- ALR
- ESD
- FAEES3
- GST1
- GST12
- GST2
- GST3
- GST4
- GST5
- GSTA1
- GSTA2
- GSTA3
- GSTA4
- GSTA5
- GSTK1
- GSTM1
- GSTM2
- GSTM3
- GSTM4
- GSTM5
- GSTO1
- GSTO2
- GSTP1
- GSTS
- GSTT1
- GSTT2
- GSTT2B
- GSTTLP28
- GSTZ1
- HPGDS
- MAAI
- MGST
- MGST1
- MGST2
- MGST3
- PGDS
- PTGDS2
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