GlyCosmos Portal

Homo sapiens (human)

Summary

Taxonomy ID: 9606
PubChem Taxonomy: 9606

Genes (1582) Glycans (5831) Glycoproteins (18496) Lectins (298) Pathways (2090)

Displaying entries **1776 - 1800** of **2090** in total

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Pathway Name	Protein Name	UniProt ID ▼	Gene Symbol	GlyTouCan ID
Ion influx/efflux at host-pathogen interface	Copper transport protein ATOX1 Copper-transporting ATPase 1 Natural resistance-associated macrophage protein 1 PDZ domain-containing protein 11	O00244 P49279 Q04656 Q5EBL8	AIPP1 ATOX1 ATP7A HAH1 LSH MC1 MNK NRAMP NRAMP1 PDZD11 PDZK11 PISP SLC11A1
Detoxification of Reactive Oxygen Species	Aquaporin-8 Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] Catalase Copper chaperone for superoxide dismutase Copper transport protein ATOX1 Copper-transporting ATPase 1 Cytochrome b-245 heavy chain Cytochrome b-245 light chain Cytochrome c ERO1-like protein alpha Epididymal secretory glutathione peroxidase Extracellular superoxide dismutase [Cu-Zn] Glutathione S-transferase P Glutathione peroxidase 1 Glutathione peroxidase 2 Glutathione peroxidase 3 Glutathione peroxidase 6 Glutathione peroxidase 7 NADPH oxidase 4 NADPH oxidase 5 Neutrophil cytosol factor 1 Neutrophil cytosol factor 2 Neutrophil cytosol factor 4 Peroxiredoxin-1 Peroxiredoxin-2 Peroxiredoxin-6 Probable glutathione peroxidase 8 Protein disulfide-isomerase Superoxide dismutase [Cu-Zn] Superoxide dismutase [Mn], mitochondrial Thioredoxin reductase 1, cytoplasmic Thioredoxin reductase 2, mitochondrial Thioredoxin, mitochondrial Thioredoxin-dependent peroxide reductase, mitochondrial Thioredoxin	O00244 O14618 O75715 O94778 P00441 P04040 P04179 P04839 P07203 P07237 P08294 P09211 P10599 P13498 P14598 P18283 P19878 P22352 P30041 P30048 P32119 P50583 P59796 P99999 Q04656 Q06830 Q15080 Q16881 Q8TED1 Q96HE7 Q96PH1 Q96SL4 Q99757 Q9NNW7 Q9NPH5	AOP1 AOP2 APAH1 AQP8 ATOX1 ATP7A CAT CCS CYBA CYBB CYC CYCS ERBA2L ERO1A ERO1L FAEES3 GPX1 GPX2 GPX3 GPX5 GPX6 GPX7 GPX8 GPXP GRIM12 GST3 GSTP1 HAH1 KDRF KIAA0106 KIAA1652 MC1 MNK NCF1 NCF2 NCF4 NKEFB NOX2 NOX4 NOX5 NOXA2 NOXO2 NUDT2 P4HB P67PHOX PAGA PAGB PDI PDIA1 PO4DB PRDX1 PRDX2 PRDX3 PRDX6 RENOX SH3PXD1A SH3PXD4 SOD1 SOD2 SOD3 TDPX1 TDPX2 TRDX TRX TRX1 TRX2 TRXR2 TXN TXN2 TXNRD1 TXNRD2
Signal regulatory protein family interactions	FYN-binding protein 1 Focal adhesion kinase 1 Leukocyte surface antigen CD47 Protein-tyrosine kinase 2-beta Signal-regulatory protein beta-1 Signal-regulatory protein gamma Src kinase-associated phosphoprotein 2 TYRO protein tyrosine kinase-binding protein Tyrosine-protein phosphatase non-receptor type 11 Tyrosine-protein phosphatase non-receptor type 6 Tyrosine-protein phosphatase non-receptor type substrate 1	O00241 O15117 O43914 O75563 P29350 P78324 Q05397 Q06124 Q08722 Q14289 Q9P1W8	BIT CD47 DAP12 FAK FAK1 FAK2 FYB FYB1 HCP KARAP MER6 MFR MYD1 PRAP PTK2 PTK2B PTP1C PTP2C PTPN11 PTPN6 PTPNS1 PYK2 RA70 RAFTK SAPS SCAP2 SHPS1 SHPTP2 SIRP SIRPA SIRPB1 SIRPB2 SIRPG SKAP2 SKAP55R SLAP130 TYROBP
Signaling by BMP	Activin receptor type-2A Activin receptor type-2B Anti-Muellerian hormone type-2 receptor Bone morphogenetic protein 10 Bone morphogenetic protein 2 Bone morphogenetic protein receptor type-1A Bone morphogenetic protein receptor type-1B Bone morphogenetic protein receptor type-2 Cerberus Chordin-like protein 1 E3 ubiquitin-protein ligase SMURF1 E3 ubiquitin-protein ligase SMURF2 Follistatin-related protein 1 Gremlin-2 Growth/differentiation factor 2 Inhibin alpha chain Inhibin beta A chain Mothers against decapentaplegic homolog 1 Mothers against decapentaplegic homolog 4 Mothers against decapentaplegic homolog 5 Mothers against decapentaplegic homolog 6 Mothers against decapentaplegic homolog 7 Mothers against decapentaplegic homolog 9 Muellerian-inhibiting factor Noggin Serine/threonine-protein kinase receptor R3 Ski oncogene Transforming growth factor beta receptor type 3 Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 D3 Zinc finger FYVE domain-containing protein 16	O00238 O15105 O15198 O43541 O95393 O95813 P03971 P05111 P08476 P12643 P12755 P27037 P36894 P37023 P51668 P61077 Q03167 Q12841 Q13253 Q13485 Q13705 Q13873 Q15797 Q16671 Q7Z3T8 Q99717 Q9BU40 Q9H772 Q9HAU4 Q9HCE7 Q9UK05	ACVR2 ACVR2A ACVR2B ACVRL1 ACVRLK1 ACVRLK3 ALK1 ALK3 AMH AMHR AMHR2 BMP10 BMP2 BMP2A BMP9 BMPR1A BMPR1B BMPR2 BSP1 CER1 CHRDL1 CKTSF1B2 DAND3 DAND4 DPC4 FRP FSTL1 GDF2 GREM2 INHA INHBA KIAA0305 KIAA1625 MADH1 MADH4 MADH5 MADH6 MADH7 MADH8 MADH9 MADR1 MIF MISR2 NOG NRLN1 PPH1 PRDC SFT SKI SMAD1 SMAD4 SMAD5 SMAD6 SMAD7 SMAD8 SMAD9 SMURF1 SMURF2 TGFBR3 UBC5A UBC5C UBCH5 UBCH5A UBCH5C UBE2D1 UBE2D3 ZFYVE16
ER Quality Control Compartment (ERQC)	Derlin-2 E3 ubiquitin-protein ligase AMFR E3 ubiquitin-protein ligase MARCHF6 E3 ubiquitin-protein ligase RNF103 E3 ubiquitin-protein ligase RNF139 E3 ubiquitin-protein ligase RNF185 E3 ubiquitin-protein ligase RNF5 E3 ubiquitin-protein ligase TRIM13 E3 ubiquitin-protein ligase synoviolin ER degradation-enhancing alpha-mannosidase-like protein 1 ER degradation-enhancing alpha-mannosidase-like protein 2 ER degradation-enhancing alpha-mannosidase-like protein 3 Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase Polyubiquitin-B Polyubiquitin-C Protein OS-9 Protein sel-1 homolog 1 UDP-glucose UDP-glucose Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00237 O60337 O60858 P0CG47 P0CG48 P62979 P62987 Q13438 Q86TM6 Q8WU17 Q92611 Q96GF1 Q99942 Q9BV94 Q9BZQ6 Q9GZP9 Q9NYU1 Q9NYU2 Q9UBV2 Q9UKM7 Q9UKV5	AMFR C1orf22 C20orf31 C20orf49 DER2 DERL2 EDEM EDEM1 EDEM2 EDEM3 FLANA G16 GT HRD1 KIAA0212 KIAA0597 KIAA1810 LEU5 MAN1B1 MARCH6 MARCHF6 NG2 OS9 RFP2 RMA1 RNF103 RNF139 RNF176 RNF185 RNF45 RNF5 RNF77 RPS27A SEL1L SYVN1 TEB4 TRC8 TRIM13 TSA305 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 UGCGL1 UGCGL2 UGGT UGGT1 UGGT2 UGT1 UGT2 UGTR ZFP103	G70323CJ G93575MM
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Cullin-1 E3 ubiquitin-protein ligase RBX1 F-box/WD repeat-containing protein 1A Glycogen synthase kinase-3 beta Nuclear factor erythroid 2-related factor 2 Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-10 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 S-phase kinase-associated protein 1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00231 O00232 O00233 O00487 O14818 O43242 O75832 P0CG47 P0CG48 P17980 P20618 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P35998 P40306 P43686 P48556 P49720 P49721 P49841 P51665 P55036 P60896 P60900 P61289 P62191 P62195 P62333 P62877 P62979 P62987 P63208 Q06323 Q13200 Q13616 Q15008 Q16236 Q16401 Q92530 Q99436 Q99460 Q9UL46 Q9UNM6 Q9Y297	BTRC BTRCP C7orf76 CUL1 DSS1 EMC19 FBW1A FBXW1A GSK3B HC2 HC3 HC8 HC9 HSPC IFI5111 KIAA0072 KIAA0107 LMP10 LMP2 LMP7 LMPX LMPY MB1 MCB1 MECL1 MIP224 MOV34L MSS1 NFE2L2 NRF2 NU OCP2 PFAAP4 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB10 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSMF1 RBX1 RING10 RING12 RNF75 ROC1 RPS27A SEM1 SHFDG1 SHFM1 SKP1 SKP1A SUG1 SUG2 TBP1 TBP7 TCEB1L TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 X Y Y2 Z
Negative regulation of NOTCH4 signaling	14-3-3 protein zeta/delta 26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Cullin-1 E3 ubiquitin-protein ligase RBX1 Neurogenic locus notch homolog protein 4 Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-10 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 RAC-alpha serine/threonine-protein kinase S-phase kinase-associated protein 1 Transforming acidic coiled-coil-containing protein 3 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00231 O00232 O00233 O00487 O14818 O43242 O75832 P0CG47 P0CG48 P17980 P20618 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P31749 P35998 P40306 P43686 P48556 P49720 P49721 P51665 P55036 P60896 P60900 P61289 P62191 P62195 P62333 P62877 P62979 P62987 P63104 P63208 Q06323 Q13200 Q13616 Q15008 Q16401 Q92530 Q99436 Q99460 Q99466 Q9UL46 Q9UNM6 Q9Y6A5	AKT1 C7orf76 CUL1 DSS1 EMC19 ERIC1 HC2 HC3 HC8 HC9 HSPC IFI5111 INT3 KIAA0072 KIAA0107 LMP10 LMP2 LMP7 LMPX LMPY MB1 MCB1 MECL1 MIP224 MOV34L MSS1 NOTCH4 NU OCP2 PFAAP4 PKB POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB10 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSMF1 RAC RBX1 RING10 RING12 RNF75 ROC1 RPS27A SEM1 SHFDG1 SHFM1 SKP1 SKP1A SUG1 SUG2 TACC3 TBP1 TBP7 TCEB1L TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 X Y Y2 YWHAZ Z
Regulation of RUNX3 expression and activity	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Core-binding factor subunit beta E3 ubiquitin-protein ligase Mdm2 E3 ubiquitin-protein ligase SMURF1 E3 ubiquitin-protein ligase SMURF2 Histone acetyltransferase p300 Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-10 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Proto-oncogene tyrosine-protein kinase Src Runt-related transcription factor 3 Transforming growth factor beta-1 proprotein Tumor suppressor ARF Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00231 O00232 O00233 O00487 O14818 O43242 O75832 P01137 P0CG47 P0CG48 P12931 P17980 P20618 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P35998 P40306 P43686 P48556 P49720 P49721 P51665 P55036 P60896 P60900 P61289 P62191 P62195 P62333 P62979 P62987 Q00987 Q06323 Q09472 Q13200 Q13761 Q13951 Q15008 Q16401 Q8N726 Q92530 Q99436 Q99460 Q9HAU4 Q9HCE7 Q9UL46 Q9UNM6	AML2 C7orf76 CBFA3 CBFB CDKN2 CDKN2A DSS1 EP300 HC2 HC3 HC8 HC9 HSPC IFI5111 KIAA0072 KIAA0107 KIAA1625 LMP10 LMP2 LMP7 LMPX LMPY MB1 MCB1 MDM2 MECL1 MIP224 MLM MOV34L MSS1 NU P300 PEBP2A3 PFAAP4 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB10 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSMF1 RING10 RING12 RPS27A RUNX3 SEM1 SHFDG1 SHFM1 SMURF1 SMURF2 SRC SRC1 SUG1 SUG2 TBP1 TBP7 TGFB TGFB1 TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 X Y Y2 Z
SCF(Skp2)-mediated degradation of p27/p21	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Cullin-1 Cyclin-A1 Cyclin-A2 Cyclin-dependent kinase 2 Cyclin-dependent kinase 4 Cyclin-dependent kinase inhibitor 1 Cyclin-dependent kinase inhibitor 1B Cyclin-dependent kinases regulatory subunit 1 G1/S-specific cyclin-D1 G1/S-specific cyclin-E1 G1/S-specific cyclin-E2 Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-10 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Protein-tyrosine kinase 6 S-phase kinase-associated protein 1 S-phase kinase-associated protein 2 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00231 O00232 O00233 O00487 O14818 O43242 O75832 O96020 P0CG47 P0CG48 P11802 P17980 P20248 P20618 P24385 P24864 P24941 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P35998 P38936 P40306 P43686 P46527 P48556 P49720 P49721 P51665 P55036 P60896 P60900 P61024 P61289 P62191 P62195 P62333 P62979 P62987 P63208 P78396 Q06323 Q13200 Q13309 Q13616 Q13882 Q15008 Q16401 Q92530 Q99436 Q99460 Q9UL46 Q9UNM6	BCL1 BRK C7orf76 CAP20 CCN1 CCNA CCNA1 CCNA2 CCND1 CCNE CCNE1 CCNE2 CDK2 CDK4 CDKN1 CDKN1A CDKN1B CDKN2 CIP1 CKS1 CKS1B CUL1 DSS1 EMC19 FBXL1 HC2 HC3 HC8 HC9 HSPC IFI5111 KIAA0072 KIAA0107 KIP1 LMP10 LMP2 LMP7 LMPX LMPY MB1 MCB1 MDA6 MECL1 MIP224 MOV34L MSS1 NU OCP2 PFAAP4 PIC1 POH1 PRAD1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB10 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSMF1 PTK6 RING10 RING12 RPS27A SDI1 SEM1 SHFDG1 SHFM1 SKP1 SKP1A SKP2 SUG1 SUG2 TBP1 TBP7 TCEB1L TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 WAF1 X Y Y2 Z p27
Autodegradation of Cdh1 by Cdh1:APC/C	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Anaphase-promoting complex subunit 10 Anaphase-promoting complex subunit 11 Anaphase-promoting complex subunit 15 Anaphase-promoting complex subunit 16 Anaphase-promoting complex subunit 1 Anaphase-promoting complex subunit 2 Anaphase-promoting complex subunit 4 Anaphase-promoting complex subunit 5 Anaphase-promoting complex subunit 7 Anaphase-promoting complex subunit CDC26 Cell division cycle protein 16 homolog Cell division cycle protein 23 homolog Cell division cycle protein 27 homolog Fizzy-related protein homolog Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-10 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Ubiquitin-conjugating enzyme E2 C Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 E1 Ubiquitin-conjugating enzyme E2 S Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00231 O00232 O00233 O00487 O00762 O14818 O43242 O75832 P0CG47 P0CG48 P17980 P20618 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P30260 P35998 P40306 P43686 P48556 P49720 P49721 P51665 P51668 P51965 P55036 P60006 P60896 P60900 P61289 P62191 P62195 P62333 P62979 P62987 Q06323 Q13042 Q13200 Q15008 Q16401 Q16763 Q8NHZ8 Q92530 Q96DE5 Q99436 Q99460 Q9H1A4 Q9NYG5 Q9UJX2 Q9UJX3 Q9UJX4 Q9UJX5 Q9UJX6 Q9UL46 Q9UM11 Q9UM13 Q9UNM6	ANAPC1 ANAPC10 ANAPC11 ANAPC12 ANAPC15 ANAPC16 ANAPC2 ANAPC3 ANAPC4 ANAPC5 ANAPC6 ANAPC7 ANAPC8 APC10 APC2 APC4 APC5 APC7 C10orf104 C11orf51 C7orf76 C9orf17 CDC16 CDC23 CDC26 CDC27 CDH1 CENP-27 D0S1430E D17S978E DSS1 E2EPF FYR FZR FZR1 HC2 HC3 HC8 HC9 HSPC IFI5111 KIAA0072 KIAA0107 KIAA1242 KIAA1406 LMP10 LMP2 LMP7 LMPX LMPY MB1 MCB1 MECL1 MIP224 MOV34L MSS1 NU PFAAP4 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB10 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSMF1 RING10 RING12 RPS27A SEM1 SFT SHFDG1 SHFM1 SUG1 SUG2 TBP1 TBP7 TRAP2 TSG24 UBA52 UBA80 UBB UBC UBC5A UBCEP1 UBCEP2 UBCH10 UBCH5 UBCH5A UBCH6 UBE2C UBE2D1 UBE2E1 UBE2S X Y Y2 Z
Assembly of the pre-replicative complex	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Anaphase-promoting complex subunit 10 Anaphase-promoting complex subunit 11 Anaphase-promoting complex subunit 15 Anaphase-promoting complex subunit 16 Anaphase-promoting complex subunit 1 Anaphase-promoting complex subunit 2 Anaphase-promoting complex subunit 4 Anaphase-promoting complex subunit 5 Anaphase-promoting complex subunit 7 Anaphase-promoting complex subunit CDC26 Cell division control protein 6 homolog Cell division cycle protein 16 homolog Cell division cycle protein 23 homolog Cell division cycle protein 27 homolog DNA replication factor Cdt1 DNA replication licensing factor MCM2 DNA replication licensing factor MCM3 DNA replication licensing factor MCM4 DNA replication licensing factor MCM5 DNA replication licensing factor MCM6 DNA replication licensing factor MCM7 Fizzy-related protein homolog Geminin Origin recognition complex subunit 1 Origin recognition complex subunit 2 Origin recognition complex subunit 3 Origin recognition complex subunit 4 Origin recognition complex subunit 5 Origin recognition complex subunit 6 Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-10 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Ubiquitin-conjugating enzyme E2 C Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 E1 Ubiquitin-conjugating enzyme E2 S Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00231 O00232 O00233 O00487 O00762 O14818 O43242 O43913 O43929 O75496 O75832 P0CG47 P0CG48 P17980 P20618 P25205 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P30260 P33991 P33992 P33993 P35998 P40306 P43686 P48556 P49720 P49721 P49736 P51665 P51668 P51965 P55036 P60006 P60896 P60900 P61289 P62191 P62195 P62333 P62979 P62987 Q06323 Q13042 Q13200 Q13415 Q13416 Q14566 Q15008 Q16401 Q16763 Q8NHZ8 Q92530 Q96DE5 Q99436 Q99460 Q99741 Q9H1A4 Q9H211 Q9NYG5 Q9UBD5 Q9UJX2 Q9UJX3 Q9UJX4 Q9UJX5 Q9UJX6 Q9UL46 Q9UM11 Q9UM13 Q9UNM6 Q9Y5N6	ANAPC1 ANAPC10 ANAPC11 ANAPC12 ANAPC15 ANAPC16 ANAPC2 ANAPC3 ANAPC4 ANAPC5 ANAPC6 ANAPC7 ANAPC8 APC10 APC2 APC4 APC5 APC7 BM28 C10orf104 C11orf51 C7orf76 C9orf17 CCNL1 CDC16 CDC18L CDC21 CDC23 CDC26 CDC27 CDC46 CDC47 CDC6 CDCL1 CDH1 CDT1 CENP-27 D0S1430E D17S978E DSS1 E2EPF FYR FZR FZR1 GMNN HC2 HC3 HC8 HC9 HSPC IFI5111 KIAA0030 KIAA0072 KIAA0107 KIAA1242 KIAA1406 LATHEO LMP10 LMP2 LMP7 LMPX LMPY MB1 MCB1 MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 MECL1 MIP224 MOV34L MSS1 NU ORC1 ORC1L ORC2 ORC2L ORC3 ORC3L ORC4 ORC4L ORC5 ORC5L ORC6 ORC6L PARC1 PFAAP4 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB10 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSMF1 RING10 RING12 RPS27A SEM1 SFT SHFDG1 SHFM1 SUG1 SUG2 TBP1 TBP7 TRAP2 TSG24 UBA52 UBA80 UBB UBC UBC5A UBCEP1 UBCEP2 UBCH10 UBCH5 UBCH5A UBCH6 UBE2C UBE2D1 UBE2E1 UBE2S X Y Y2 Z
Peptide ligand-binding receptors	Adrenocorticotropic hormone receptor Angiotensinogen Apelin receptor Apelin Atypical chemokine receptor 1 B1 bradykinin receptor B2 bradykinin receptor Bombesin receptor subtype-3 C3a anaphylatoxin chemotactic receptor C5a anaphylatoxin chemotactic receptor 1 C5a anaphylatoxin chemotactic receptor 2 Cholecystokinin receptor type A Cholecystokinin Complement C3 Complement C5 Cortistatin Delta-type opioid receptor Endoplasmic reticulum membrane adapter protein XK Endothelin receptor type B Endothelin-1 receptor Endothelin-1 Endothelin-2 Endothelin-3 Endothelin-converting enzyme 1 Endothelin-converting enzyme 2 G-protein coupled estrogen receptor 1 G-protein coupled receptor 37-like 1 Galanin peptides Galanin receptor type 1 Galanin receptor type 2 Galanin receptor type 3 Gastrin-releasing peptide receptor Gastrin-releasing peptide Gastrin/cholecystokinin type B receptor Growth hormone secretagogue receptor type 1 Interleukin-8 Kappa-type opioid receptor Kell blood group glycoprotein KiSS-1 receptor Kininogen-1 Melanin-concentrating hormone receptor 1 Melanin-concentrating hormone receptor 2 Melanocortin receptor 3 Melanocortin receptor 4 Melanocortin receptor 5 Melanocyte-stimulating hormone receptor Metastasis-suppressor KiSS-1 Motilin receptor Mu-type opioid receptor Neurolysin, mitochondrial Neuromedin-B receptor Neuromedin-B Neuromedin-S Neuromedin-U receptor 1 Neuromedin-U receptor 2 Neuromedin-U Neuropeptide B Neuropeptide S receptor Neuropeptide S Neuropeptide W Neuropeptide Y receptor type 1 Neuropeptide Y receptor type 2 Neuropeptide Y receptor type 4 Neuropeptide Y receptor type 5 Neuropeptides B/W receptor type 1 Neuropeptides B/W receptor type 2 Neurotensin receptor type 1 Neurotensin receptor type 2 Neurotensin/neuromedin N Nociceptin receptor Pancreatic polypeptide prohormone Peptide YY Prepronociceptin Pro-MCH Pro-neuropeptide Y Pro-opiomelanocortin Pro-thyrotropin-releasing hormone Proenkephalin-A Proenkephalin-B Prokineticin receptor 1 Prokineticin receptor 2 Prokineticin-1 Prokineticin-2 Prolactin-releasing peptide receptor Prolactin-releasing peptide Promotilin Prosaposin receptor GPR37 Prosaposin Proteinase-activated receptor 1 Proteinase-activated receptor 2 Proteinase-activated receptor 3 Proteinase-activated receptor 4 Prothrombin Somatostatin receptor type 1 Somatostatin receptor type 2 Somatostatin receptor type 3 Somatostatin receptor type 4 Somatostatin receptor type 5 Somatostatin Thyrotropin-releasing hormone receptor Type-1 angiotensin II receptor Type-2 angiotensin II receptor Urotensin-2 receptor Urotensin-2 Urotensin-2B	O00230 O00254 O15354 O43193 O43603 O60755 O60883 O95399 O95665 P00734 P01019 P01024 P01031 P01042 P01189 P01210 P01213 P01298 P01303 P05305 P06307 P07492 P07602 P08949 P0C0P6 P0DPD6 P10082 P10145 P12872 P14138 P20382 P20396 P20800 P21730 P22466 P23276 P24530 P25101 P25116 P25929 P28336 P30411 P30550 P30556 P30872 P30874 P30989 P30990 P31391 P32238 P32239 P32245 P32247 P32745 P33032 P34981 P35346 P35372 P35414 P41143 P41145 P41146 P41968 P42892 P46663 P47211 P48145 P48146 P48645 P49146 P49683 P50052 P50391 P51811 P55085 P58294 P61278 P81277 Q01718 Q01726 Q13519 Q15726 Q15761 Q16570 Q16581 Q5H8A3 Q6W5P4 Q765I0 Q8N729 Q8NFJ6 Q8NG41 Q8TCW9 Q92847 Q969F8 Q969V1 Q96RI0 Q99527 Q99705 Q9BYT8 Q9GZQ4 Q9HB89 Q9HC23 Q9P296 Q9UKP6 Q9ULZ1	ACKR1 ACTHR AGT AGTBP AGTR1 AGTR1A AGTR1B AGTR2 AGTRL1 APEL APJ APLN APLNR AT2R1 AT2R1B AXOR12 AZ3B BDK BDKRB1 BDKRB2 BKR2 BRADYB1 BRS3 BV8 C3 C3AR1 C3R1 C5 C5AR C5AR1 C5AR2 C5L2 C5R1 CCK CCKAR CCKBR CCKRA CCKRB CEPR CF2R CMKRL2 CORT CPAMD1 CPAMD4 CXCL8 DARC DRY12 ECE1 ECE2 EDN1 EDN2 EDN3 EDNRA EDNRB ETA ETBRLP2 ETRA ETRB F2 F2R F2RL1 F2RL2 F2RL3 FY GAL GAL1 GALN GALNR GALNR1 GALNR2 GALNR3 GALR1 GALR2 GALR3 GHSR GLBA GLNN GPD GPER GPER1 GPR10 GPR11 GPR14 GPR145 GPR154 GPR24 GPR30 GPR37 GPR37L1 GPR38 GPR54 GPR66 GPR7 GPR73 GPR73L1 GPR77 GPR8 GPRA GR3 GRP GRPR HNFAG09 IL8 KEL KIAA0604 KIAA1226 KISS1 KISS1R KNG KNG1 MC1R MC2R MC3R MC4R MC5R MCH MCHR1 MCHR2 MLN MLNR MOR1 MSHR MTLR MTLR1 NLN NMB NMBR NMS NMU NMU2R NMUR1 NMUR2 NPB NPBWR1 NPBWR2 NPS NPSR1 NPW NPY NPY1R NPY2R NPY4R NPY5R NPYR NPYR5 NPYY1 NTRR NTS NTSR1 NTSR2 OFQ OOR OPRD OPRD1 OPRK OPRK1 OPRL1 OPRM1 ORL1 PAR1 PAR2 PAR3 PAR4 PDYN PENK PGR14 PKR1 PKR2 PMCH PNOC PNP POMC PPL7 PPL8 PPNPB PPNPW PPY PPYR1 PRH PRLH PRLHR PROK1 PROK2 PROKR1 PROKR2 PSAP PYY SAP1 SERPINA8 SLC1 SLT SST SSTR1 SSTR2 SSTR3 SSTR4 SSTR5 TGR1 TR TRH TRHR URP UTS2 UTS2B UTS2D UTS2R XK XKR1 XRG1
Class C/3 (Metabotropic glutamate/pheromone receptors)	Extracellular calcium-sensing receptor G-protein coupled receptor family C group 6 member A Gamma-aminobutyric acid type B receptor subunit 1 Gamma-aminobutyric acid type B receptor subunit 2 Metabotropic glutamate receptor 1 Metabotropic glutamate receptor 2 Metabotropic glutamate receptor 3 Metabotropic glutamate receptor 4 Metabotropic glutamate receptor 5 Metabotropic glutamate receptor 6 Metabotropic glutamate receptor 7 Metabotropic glutamate receptor 8 Taste receptor type 1 member 1 Taste receptor type 1 member 2 Taste receptor type 1 member 3 Taste receptor type 2 member 10 Taste receptor type 2 member 13 Taste receptor type 2 member 14 Taste receptor type 2 member 16 Taste receptor type 2 member 19 Taste receptor type 2 member 1 Taste receptor type 2 member 20 Taste receptor type 2 member 30 Taste receptor type 2 member 31 Taste receptor type 2 member 38 Taste receptor type 2 member 39 Taste receptor type 2 member 3 Taste receptor type 2 member 40 Taste receptor type 2 member 41 Taste receptor type 2 member 42 Taste receptor type 2 member 43 Taste receptor type 2 member 45 Taste receptor type 2 member 46 Taste receptor type 2 member 4 Taste receptor type 2 member 50 Taste receptor type 2 member 5 Taste receptor type 2 member 60 Taste receptor type 2 member 7 Taste receptor type 2 member 8 Taste receptor type 2 member 9	O00222 O15303 O75899 P41180 P41594 P59533 P59534 P59535 P59536 P59537 P59538 P59539 P59540 P59541 P59542 P59543 P59544 P59551 Q13255 Q14416 Q14831 Q14832 Q14833 Q5T6X5 Q7RTR8 Q7RTX0 Q7RTX1 Q8TE23 Q9NYV7 Q9NYV8 Q9NYV9 Q9NYW0 Q9NYW1 Q9NYW2 Q9NYW3 Q9NYW4 Q9NYW5 Q9NYW6 Q9NYW7 Q9UBS5	CASR GABBR1 GABBR2 GPR51 GPR59 GPR60 GPR70 GPR71 GPRC1A GPRC1B GPRC1C GPRC1D GPRC1E GPRC1F GPRC1G GPRC1H GPRC2A GPRC3A GPRC3B GPRC6A GRM1 GRM2 GRM3 GRM4 GRM5 GRM6 GRM7 GRM8 MGLUR1 MGLUR2 MGLUR3 MGLUR4 MGLUR5 MGLUR6 MGLUR7 MGLUR8 PCAR1 PTC T1R1 T1R2 T1R3 TAS1R1 TAS1R2 TAS1R3 TAS2R1 TAS2R10 TAS2R13 TAS2R14 TAS2R16 TAS2R19 TAS2R20 TAS2R23 TAS2R3 TAS2R30 TAS2R31 TAS2R38 TAS2R39 TAS2R4 TAS2R40 TAS2R41 TAS2R42 TAS2R43 TAS2R44 TAS2R45 TAS2R46 TAS2R47 TAS2R48 TAS2R49 TAS2R5 TAS2R50 TAS2R55 TAS2R60 TAS2R7 TAS2R8 TAS2R9 TR1 TR2 TR3	G58161NS
CASP8 activity is inhibited	Caspase-8 FAS-associated death domain protein Receptor-interacting serine/threonine-protein kinase 1 TNF receptor-associated factor 2 Tumor necrosis factor ligand superfamily member 10 Tumor necrosis factor ligand superfamily member 6 Tumor necrosis factor receptor superfamily member 10A Tumor necrosis factor receptor superfamily member 10B Tumor necrosis factor receptor superfamily member 6 Tumor necrosis factor receptor type 1-associated DEATH domain protein	O00220 O14763 P25445 P48023 P50591 Q12933 Q13158 Q13546 Q14790 Q15628	APO2 APO2L APT1 APT1LG1 CASP8 CD95L DR4 DR5 FADD FAS FAS1 FASL FASLG KILLER MCH5 MORT1 RIP RIP1 RIPK1 TNFRSF10A TNFRSF10B TNFRSF6 TNFSF10 TNFSF6 TRADD TRAF2 TRAIL TRAILR1 TRAILR2 TRAP3 TRICK2 ZTNFR9
Regulation by c-FLIP	Caspase-8 FAS-associated death domain protein Receptor-interacting serine/threonine-protein kinase 1 TNF receptor-associated factor 2 Tumor necrosis factor ligand superfamily member 10 Tumor necrosis factor ligand superfamily member 6 Tumor necrosis factor receptor superfamily member 10A Tumor necrosis factor receptor superfamily member 10B Tumor necrosis factor receptor superfamily member 6 Tumor necrosis factor receptor type 1-associated DEATH domain protein	O00220 O14763 P25445 P48023 P50591 Q12933 Q13158 Q13546 Q14790 Q15628	APO2 APO2L APT1 APT1LG1 CASP8 CD95L DR4 DR5 FADD FAS FAS1 FASL FASLG KILLER MCH5 MORT1 RIP RIP1 RIPK1 TNFRSF10A TNFRSF10B TNFRSF6 TNFSF10 TNFSF6 TRADD TRAF2 TRAIL TRAILR1 TRAILR2 TRAP3 TRICK2 ZTNFR9
Dimerization of procaspase-8	Caspase-8 FAS-associated death domain protein Receptor-interacting serine/threonine-protein kinase 1 TNF receptor-associated factor 2 Tumor necrosis factor ligand superfamily member 10 Tumor necrosis factor ligand superfamily member 6 Tumor necrosis factor receptor superfamily member 10A Tumor necrosis factor receptor superfamily member 10B Tumor necrosis factor receptor superfamily member 6 Tumor necrosis factor receptor type 1-associated DEATH domain protein	O00220 O14763 P25445 P48023 P50591 Q12933 Q13158 Q13546 Q14790 Q15628	APO2 APO2L APT1 APT1LG1 CASP8 CD95L DR4 DR5 FADD FAS FAS1 FASL FASLG KILLER MCH5 MORT1 RIP RIP1 RIPK1 TNFRSF10A TNFRSF10B TNFRSF6 TNFSF10 TNFSF6 TRADD TRAF2 TRAIL TRAILR1 TRAILR2 TRAP3 TRICK2 ZTNFR9
TRAIL signaling	CASP8 and FADD-like apoptosis regulator Caspase-10 Caspase-8 FAS-associated death domain protein Tumor necrosis factor ligand superfamily member 10 Tumor necrosis factor receptor superfamily member 10A Tumor necrosis factor receptor superfamily member 10B Tumor necrosis factor receptor superfamily member 10D	O00220 O14763 O15519 P50591 Q13158 Q14790 Q92851 Q9UBN6	APO2 APO2L CASH CASP10 CASP8 CASP8AP1 CFLAR CLARP DCR2 DR4 DR5 FADD KILLER MCH4 MCH5 MORT1 MRIT TNFRSF10A TNFRSF10B TNFRSF10D TNFSF10 TRAIL TRAILR1 TRAILR2 TRAILR4 TRICK2 TRUNDD ZTNFR9
TP53 Regulates Transcription of Death Receptors and Ligands	Apoptosis-stimulating of p53 protein 1 Apoptosis-stimulating of p53 protein 2 Cellular tumor antigen p53 Insulin-like growth factor-binding protein 3 receptor Insulin-like growth factor-binding protein 3 Tumor necrosis factor receptor superfamily member 10A Tumor necrosis factor receptor superfamily member 10B Tumor necrosis factor receptor superfamily member 10C Tumor necrosis factor receptor superfamily member 10D Tumor necrosis factor receptor superfamily member 6 Tumor protein 63 Tumor protein p73	O00220 O14763 O14798 O15350 P04637 P17936 P25445 Q13625 Q86XT9 Q96KQ4 Q9H3D4 Q9UBN6	APO2 APT1 ASPP1 ASPP2 BBP DCR1 DCR2 DR4 DR5 FAS FAS1 IBP3 IGFBP3 KET KIAA0771 KILLER LIT P53 P63 P73 P73H P73L PPP1R13B TMEM219 TNFRSF10A TNFRSF10B TNFRSF10C TNFRSF10D TNFRSF6 TP53 TP53BP2 TP63 TP73 TP73L TRAILR1 TRAILR2 TRAILR3 TRAILR4 TRICK2 TRID TRUNDD ZTNFR9
RIPK1-mediated regulated necrosis	Baculoviral IAP repeat-containing protein 2 Baculoviral IAP repeat-containing protein 3 Caspase-8 E3 ubiquitin-protein ligase CHIP E3 ubiquitin-protein ligase XIAP FAS-associated death domain protein Flotillin-1 Flotillin-2 Mixed lineage kinase domain-like protein Non-structural protein 1 Programmed cell death 6-interacting protein Receptor-interacting serine/threonine-protein kinase 1 Receptor-interacting serine/threonine-protein kinase 3 Ribonucleoside-diphosphate reductase large subunit Syntenin-1 TNF receptor-associated factor 2 Tumor necrosis factor ligand superfamily member 10 Tumor necrosis factor ligand superfamily member 6 Tumor necrosis factor receptor superfamily member 10A Tumor necrosis factor receptor superfamily member 10B Tumor necrosis factor receptor superfamily member 6 Tumor necrosis factor receptor type 1-associated DEATH domain protein UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit	O00220 O00560 O14763 O15294 O75955 P03496 P08543 P25445 P48023 P50591 P98170 Q12933 Q13158 Q13489 Q13490 Q13546 Q14254 Q14790 Q15628 Q8NB16 Q8WUM4 Q9UNE7 Q9Y572	AIP1 ALIX API1 API2 API3 APO2 APO2L APT1 APT1LG1 BIRC2 BIRC3 BIRC4 CASP8 CD95L CHIP DR4 DR5 ESA1 FADD FAS FAS1 FASL FASLG FLOT1 FLOT2 IAP3 ICP6 KIAA1375 KILLER M17S1 MCH5 MDA9 MIHB MIHC MLKL MORT1 NS OGT PDCD6IP RIP RIP1 RIP3 RIPK1 RIPK3 RIR1 RNF48 RNF49 SDCBP STUB1 SYCL TNFRSF10A TNFRSF10B TNFRSF6 TNFSF10 TNFSF6 TRADD TRAF2 TRAIL TRAILR1 TRAILR2 TRAP3 TRICK2 XIAP ZTNFR9
Hyaluronan biosynthesis and export	ATP-binding cassette sub-family C member 5 Cell migration-inducing and hyaluronan-binding protein Hyaluronan synthase 1 Hyaluronan synthase 2 Hyaluronan synthase 3	O00219 O15440 Q8WUJ3 Q92819 Q92839	ABCC5 CEMIP HAS HAS1 HAS2 HAS3 HYBID KIAA1199 MRP5	G35674CY
Complex I biogenesis	Acyl carrier protein, mitochondrial Arginine-hydroxylase NDUFAF5, mitochondrial Complex I assembly factor ACAD9, mitochondrial Complex I assembly factor TIMMDC1, mitochondrial Complex I assembly factor TMEM126B, mitochondrial Complex I intermediate-associated protein 30, mitochondrial Cytochrome c oxidase assembly factor 1 homolog Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial Iron-sulfur cluster transfer protein NUBPL NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial NADH dehydrogenase [ubiquinone] 1 subunit C2 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial NADH-ubiquinone oxidoreductase chain 1 NADH-ubiquinone oxidoreductase chain 2 NADH-ubiquinone oxidoreductase chain 3 NADH-ubiquinone oxidoreductase chain 4 NADH-ubiquinone oxidoreductase chain 5 NADH-ubiquinone oxidoreductase chain 6 Protein arginine methyltransferase NDUFAF7, mitochondrial Transmembrane protein 186	O00217 O14561 O15239 O43181 O43674 O43676 O43677 O43678 O43920 O75251 O75306 O75380 O75438 O75489 O95139 O95167 O95168 O95169 O95178 O95182 O95298 O95299 O96000 P03886 P03891 P03897 P03905 P03915 P03923 P17568 P19404 P28331 P49821 P51970 P56181 P56556 Q16718 Q16795 Q330K2 Q5TEU4 Q7L592 Q86Y39 Q8IUX1 Q8N183 Q8TB37 Q96B77 Q9BQ95 Q9BU61 Q9GZY4 Q9H845 Q9NPL8 Q9NX14 Q9P032 Q9P0J0 Q9UI09 Q9Y375 Q9Y6M9	ACAD9 C14orf127 C16orf51 C20orf7 C2orf56 C3orf1 C3orf60 C6orf66 C7orf44 C8orf38 CIA30 COA1 DAP13 ECSIT GRIM19 HRPAP20 LYRM3 LYRM6 MITRAC15 MT-ND1 MT-ND2 MT-ND3 MT-ND4 MT-ND5 MT-ND6 MTND1 MTND2 MTND3 MTND4 MTND5 MTND6 NADH1 NADH2 NADH3 NADH4 NADH5 NADH6 NADHB14 ND1 ND2 ND3 ND4 ND5 ND6 NDUFA1 NDUFA10 NDUFA11 NDUFA12 NDUFA12L NDUFA13 NDUFA2 NDUFA3 NDUFA5 NDUFA6 NDUFA7 NDUFA8 NDUFA9 NDUFAB1 NDUFAF1 NDUFAF2 NDUFAF3 NDUFAF4 NDUFAF5 NDUFAF6 NDUFAF7 NDUFB1 NDUFB10 NDUFB11 NDUFB2 NDUFB3 NDUFB4 NDUFB5 NDUFB6 NDUFB7 NDUFB8 NDUFB9 NDUFC1 NDUFC2 NDUFS1 NDUFS2 NDUFS2L NDUFS3 NDUFS4 NDUFS5 NDUFS6 NDUFS7 NDUFS8 NDUFV1 NDUFV2 NDUFV3 NUBPL TIMMDC1 TMEM126B TMEM186 UQOR1 UQOR22
Respiratory electron transport	Acyl carrier protein, mitochondrial Coenzyme Q-binding protein COQ10 homolog A, mitochondrial Coenzyme Q-binding protein COQ10 homolog B, mitochondrial Cytochrome b-c1 complex subunit 1, mitochondrial Cytochrome b-c1 complex subunit 10 Cytochrome b-c1 complex subunit 2, mitochondrial Cytochrome b-c1 complex subunit 6, mitochondrial Cytochrome b-c1 complex subunit 7 Cytochrome b-c1 complex subunit 8 Cytochrome b-c1 complex subunit 9 Cytochrome b-c1 complex subunit Rieske, mitochondrial Cytochrome b Cytochrome c oxidase assembly factor 1 homolog Cytochrome c oxidase assembly protein COX11, mitochondrial Cytochrome c oxidase assembly protein COX14 Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial Cytochrome c oxidase assembly protein COX18, mitochondrial Cytochrome c oxidase assembly protein COX19 Cytochrome c oxidase assembly protein COX20, mitochondrial Cytochrome c oxidase subunit 1 Cytochrome c oxidase subunit 2 Cytochrome c oxidase subunit 3 Cytochrome c oxidase subunit 4 isoform 1, mitochondrial Cytochrome c oxidase subunit 5A, mitochondrial Cytochrome c oxidase subunit 5B, mitochondrial Cytochrome c oxidase subunit 6A1, mitochondrial Cytochrome c oxidase subunit 6B1 Cytochrome c oxidase subunit 6C Cytochrome c oxidase subunit 7A-related protein, mitochondrial Cytochrome c oxidase subunit 7B, mitochondrial Cytochrome c oxidase subunit 7C, mitochondrial Cytochrome c oxidase subunit 8A, mitochondrial Cytochrome c oxidase subunit NDUFA4 Cytochrome c1, heme protein, mitochondrial Cytochrome c Electron transfer flavoprotein subunit alpha, mitochondrial Electron transfer flavoprotein subunit beta Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial Heat shock protein 75 kDa, mitochondrial Leucine-rich PPR motif-containing protein, mitochondrial NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial NADH dehydrogenase [ubiquinone] 1 subunit C2 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial NADH-ubiquinone oxidoreductase chain 1 NADH-ubiquinone oxidoreductase chain 2 NADH-ubiquinone oxidoreductase chain 3 NADH-ubiquinone oxidoreductase chain 4 NADH-ubiquinone oxidoreductase chain 5 NADH-ubiquinone oxidoreductase chain 6 Protein SCO1 homolog, mitochondrial Protein SCO2 homolog, mitochondrial Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial Succinate dehydrogenase cytochrome b560 subunit, mitochondrial Surfeit locus protein 1 Translational activator of cytochrome c oxidase 1 Transmembrane protein 186	O00217 O00483 O14521 O14548 O14561 O14949 O14957 O15239 O43181 O43674 O43676 O43677 O43678 O43819 O43920 O75251 O75306 O75380 O75438 O75489 O75880 O95139 O95167 O95168 O95169 O95178 O95182 O95298 O95299 O96000 P00156 P00395 P00403 P00414 P03886 P03891 P03897 P03905 P03915 P03923 P07919 P08574 P09669 P10176 P10606 P12074 P13073 P13804 P14854 P14927 P15954 P17568 P19404 P20674 P21912 P22695 P24311 P28331 P31040 P31930 P38117 P42704 P47985 P49821 P51970 P56181 P56556 P99999 Q12931 Q15526 Q16134 Q16718 Q16795 Q49B96 Q5RI15 Q86Y39 Q8N8Q8 Q96B77 Q96I36 Q96MF6 Q99643 Q9BSH4 Q9GZY4 Q9H8M1 Q9NX14 Q9P0J0 Q9P0S2 Q9UDW1 Q9UI09 Q9Y6M9 Q9Y6N1	C12orf62 C14orf112 C16orf51 C7orf44 CCDC44 COA1 COB COI COII COIII COQ10A COQ10B COX11 COX14 COX16 COX18 COX19 COX2 COX20 COX4 COX4I1 COX5A COX5B COX6A1 COX6AL COX6B COX6B1 COX6C COX7A2L COX7AR COX7B COX7C COX7RP COX8 COX8A COX8L COXI COXII COXIII CYB560 CYC CYC1 CYCS CYTB DAP13 ETFA ETFB ETFDH FAM36A GRIM19 HSP75 HSPC5 LRP130 LRPPRC LYRM3 LYRM6 MITRAC15 MT-CO1 MT-CO2 MT-CO3 MT-CYB MT-ND1 MT-ND2 MT-ND3 MT-ND4 MT-ND5 MT-ND6 MTCO1 MTCO2 MTCO3 MTCYB MTND1 MTND2 MTND3 MTND4 MTND5 MTND6 NADH1 NADH2 NADH3 NADH4 NADH5 NADH6 NADHB14 ND1 ND2 ND3 ND4 ND5 ND6 NDUFA1 NDUFA10 NDUFA11 NDUFA12 NDUFA13 NDUFA2 NDUFA3 NDUFA4 NDUFA5 NDUFA6 NDUFA7 NDUFA8 NDUFA9 NDUFAB1 NDUFB1 NDUFB10 NDUFB11 NDUFB2 NDUFB3 NDUFB4 NDUFB5 NDUFB6 NDUFB7 NDUFB8 NDUFB9 NDUFC1 NDUFC2 NDUFS1 NDUFS2 NDUFS2L NDUFS3 NDUFS4 NDUFS5 NDUFS6 NDUFS7 NDUFS8 NDUFV1 NDUFV2 NDUFV3 OXA1L2 SCO1 SCO2 SCOD1 SDH SDH1 SDH2 SDH3 SDH4 SDHA SDHB SDHC SDHD SDHF SURF-1 SURF1 TACO1 TMEM186 TRAP1 UCRC UQBP UQCR UQCR10 UQCR11 UQCRB UQCRC1 UQCRC2 UQCRFS1 UQCRH UQCRQ UQOR1 UQOR22
MyD88-independent TLR4 cascade	Lymphocyte antigen 96 Monocyte differentiation antigen CD14 TIR domain-containing adapter molecule 1 TIR domain-containing adapter molecule 2 Toll-like receptor 4	O00206 P08571 Q86XR7 Q8IUC6 Q9Y6Y9	CD14 ESOP1 LY96 MD2 PRVTIRB TICAM1 TICAM2 TIRAP3 TIRP TLR4 TRAM TRIF
TRIF-mediated programmed cell death	Caspase-8 FAS-associated death domain protein Lymphocyte antigen 96 Monocyte differentiation antigen CD14 Receptor-interacting serine/threonine-protein kinase 1 Receptor-interacting serine/threonine-protein kinase 3 TIR domain-containing adapter molecule 1 TIR domain-containing adapter molecule 2 Toll-like receptor 4	O00206 P08571 Q13158 Q13546 Q14790 Q86XR7 Q8IUC6 Q9Y572 Q9Y6Y9	CASP8 CD14 ESOP1 FADD LY96 MCH5 MD2 MORT1 PRVTIRB RIP RIP1 RIP3 RIPK1 RIPK3 TICAM1 TICAM2 TIRAP3 TIRP TLR4 TRAM TRIF
Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7	Inhibitor of nuclear factor kappa-B kinase subunit epsilon Lymphocyte antigen 96 Monocyte differentiation antigen CD14 Optineurin Polyubiquitin-B Polyubiquitin-C Serine/threonine-protein kinase TBK1 TIR domain-containing adapter molecule 1 TIR domain-containing adapter molecule 2 TNF receptor-associated factor 3 TRAF family member-associated NF-kappa-B activator Toll-like receptor 4 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00206 P08571 P0CG47 P0CG48 P62979 P62987 Q13114 Q14164 Q86XR7 Q8IUC6 Q92844 Q96CV9 Q9UHD2 Q9Y6Y9	CAP-1 CD14 CRAF1 ESOP1 FIP2 GLC1E HIP7 HYPL IKBKE IKKE IKKI ITRAF KIAA0151 LY96 MD2 NAK NRP OPTN PRVTIRB RPS27A TANK TBK1 TICAM1 TICAM2 TIRAP3 TIRP TLR4 TRAF2 TRAF3 TRAFAMN TRAM TRIF UBA52 UBA80 UBB UBC UBCEP1 UBCEP2

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