GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **426 - 450** of **2090** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▲	Organism
Glucagon signaling in metabolic regulation	Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Adenylate cyclase type 9 Glucagon receptor Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Guanine nucleotide-binding protein subunit beta-4 Pro-glucagon	O43306 O60262 O60266 O60503 O95622 P01275 P16520 P40145 P47871 P50150 P50151 P51828 P59768 P61952 P62873 P62879 P63092 P63215 P63218 Q08462 Q08828 Q5JWF2 Q8NFM4 Q9HAV0 Q9P2W3 Q9UBI6 Q9UK08	ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 GCG GCGR GNAS GNAS1 GNB1 GNB2 GNB3 GNB4 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT10 GNGT11 GNGT3 GNGT4 GNGT5 GNGT7 GNGT9 GSP KIAA0037 KIAA0422 KIAA0511 KIAA0520 KIAA1060	Homo sapiens (human)
Adenylate cyclase inhibitory pathway	Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Adenylate cyclase type 9 Guanine nucleotide-binding protein G(i) subunit alpha-1 Guanine nucleotide-binding protein G(i) subunit alpha-2 Guanine nucleotide-binding protein G(i) subunit alpha-3 Guanine nucleotide-binding protein G(olf) subunit alpha Guanine nucleotide-binding protein G(t) subunit alpha-3	A8MTJ3 O43306 O60266 O60503 O95622 P04899 P08754 P38405 P40145 P51828 P63096 Q08462 Q08828 Q8NFM4	ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 GNAI1 GNAI2 GNAI2B GNAI3 GNAL GNAT3 KIAA0037 KIAA0422 KIAA0511 KIAA0520 KIAA1060	Homo sapiens (human)
Adenylate cyclase activating pathway	Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Adenylate cyclase type 9 Guanine nucleotide-binding protein G(olf) subunit alpha	O43306 O60266 O60503 O95622 P38405 P40145 P51828 Q08462 Q08828 Q8NFM4	ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 GNAL KIAA0037 KIAA0422 KIAA0511 KIAA0520 KIAA1060	Homo sapiens (human)
PKA activation in glucagon signalling	Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Adenylate cyclase type 9 Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas Guanine nucleotide-binding protein G(s) subunit alpha isoforms short cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit gamma cAMP-dependent protein kinase type I-alpha regulatory subunit cAMP-dependent protein kinase type I-beta regulatory subunit cAMP-dependent protein kinase type II-alpha regulatory subunit cAMP-dependent protein kinase type II-beta regulatory subunit	O43306 O60266 O60503 O95622 P10644 P13861 P17612 P22612 P22694 P31321 P31323 P40145 P51828 P63092 Q08462 Q08828 Q5JWF2 Q8NFM4	ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 GNAS GNAS1 GSP KIAA0037 KIAA0422 KIAA0511 KIAA0520 KIAA1060 PKACA PKR1 PKR2 PRKACA PRKACB PRKACG PRKAR1 PRKAR1A PRKAR1B PRKAR2 PRKAR2A PRKAR2B TSE1	Homo sapiens (human)
CREB1 phosphorylation through the activation of Adenylate Cyclase	Adenylate cyclase type 1 Adenylate cyclase type 8 Calmodulin-1 cAMP-dependent protein kinase catalytic subunit PRKX cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit gamma cAMP-dependent protein kinase type I-alpha regulatory subunit cAMP-dependent protein kinase type I-beta regulatory subunit cAMP-dependent protein kinase type II-alpha regulatory subunit cAMP-dependent protein kinase type II-beta regulatory subunit	P0DP23 P10644 P13861 P17612 P22612 P22694 P31321 P31323 P40145 P51817 Q08828	ADCY1 ADCY8 CALM CALM1 CAM CAM1 PKACA PKR1 PKR2 PKX1 PRKACA PRKACB PRKACG PRKAR1 PRKAR1A PRKAR1B PRKAR2 PRKAR2A PRKAR2B PRKX TSE1	Homo sapiens (human)
Olfactory Signaling Pathway	Adenylate cyclase type 3 Anoctamin-2 Cyclic nucleotide-gated channel alpha-2 Cyclic nucleotide-gated channel alpha-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(olf) subunit alpha Olfactory receptor 10A6 Olfactory receptor 10G3 Olfactory receptor 10G4 Olfactory receptor 10G7 Olfactory receptor 10H2 Olfactory receptor 10H5 Olfactory receptor 10J5 Olfactory receptor 10S1 Olfactory receptor 10X1 Olfactory receptor 11A1 Olfactory receptor 11H4 Olfactory receptor 11H6 Olfactory receptor 13C3 Olfactory receptor 14A2 Olfactory receptor 14J1 Olfactory receptor 1A1 Olfactory receptor 1C1 Olfactory receptor 1D2 Olfactory receptor 1D5 Olfactory receptor 1E1 Olfactory receptor 1N2 Olfactory receptor 2A1/2A42 Olfactory receptor 2A25 Olfactory receptor 2A7 Olfactory receptor 2AT4 Olfactory receptor 2B11 Olfactory receptor 2C1 Olfactory receptor 2F1 Olfactory receptor 2J1 Olfactory receptor 2J2 Olfactory receptor 2J3 Olfactory receptor 2L13 Olfactory receptor 2M2 Olfactory receptor 2M7 Olfactory receptor 2S2 Olfactory receptor 2T1 Olfactory receptor 2T4 Olfactory receptor 2W1 Olfactory receptor 2W3 Olfactory receptor 3A1 Olfactory receptor 4C12 Olfactory receptor 4D2 Olfactory receptor 4F17 Olfactory receptor 4L1 Olfactory receptor 4Q3 Olfactory receptor 51B5 Olfactory receptor 51D1 Olfactory receptor 51E1 Olfactory receptor 51E2 Olfactory receptor 51L1 Olfactory receptor 52B6 Olfactory receptor 56A4 Olfactory receptor 5AL1 Olfactory receptor 5D14 Olfactory receptor 5K1 Olfactory receptor 5P3 Olfactory receptor 6F1 Olfactory receptor 6P1 Olfactory receptor 7C1 Olfactory receptor 7D4 Olfactory receptor 7G2 Olfactory receptor 8B3 Olfactory receptor 8D1 Olfactory receptor 8K3 Olfactory receptor 8U8 Olfactory receptor 9G1	A4D2G3 A6NND4 O43869 O60266 O60403 O76001 O76002 O76099 O95371 P0C617 P0C7N1 P30953 P34982 P38405 P47881 P58170 P58180 P62873 Q13607 Q15619 Q16280 Q5JQS5 Q7Z3T1 Q8IV77 Q8N349 Q8NG81 Q8NG98 Q8NG99 Q8NGA6 Q8NGA8 Q8NGC4 Q8NGC7 Q8NGC9 Q8NGF0 Q8NGF3 Q8NGG8 Q8NGH8 Q8NGJ5 Q8NGL3 Q8NGN2 Q8NGN3 Q8NGN6 Q8NGR9 Q8NGS6 Q8NGT9 Q8NGX9 Q8NGY0 Q8NGZ6 Q8NH00 Q8NH05 Q8NH43 Q8NH51 Q8NH74 Q8NH87 Q8NHB7 Q8NHC4 Q8TCB6 Q8WZ84 Q8WZ94 Q96R28 Q96R45 Q96R54 Q96R67 Q9GZK6 Q9GZK7 Q9H255 Q9H339 Q9NQ90 Q9NQN1 Q9P1Q5 Q9P2W3 Q9UGF5 Q9Y3N9	ADCY3 ANO2 C12orf3 C14orf13 CNCA CNCA1 CNCG2 CNGA2 CNGA4 GNAL GNB1 GNG13 GPR164 KIAA0511 OLF3 OLFR1 OLFRA03 OR10A6 OR10G3 OR10G4 OR10G7 OR10H2 OR10H5 OR10J5 OR10S1 OR10X1 OR10X1P OR11A1 OR11A2 OR11H4 OR11H6 OR13C3 OR14A2 OR14J1 OR1A1 OR1C1 OR1D2 OR1D5 OR1E1 OR1E5 OR1E6 OR1E9P OR1N2 OR2A1 OR2A25 OR2A25P OR2A27 OR2A42 OR2A7 OR2AT4 OR2B11 OR2C1 OR2C2P OR2F1 OR2F3 OR2F3P OR2F4 OR2F5 OR2J1 OR2J1P OR2J2 OR2J3 OR2L13 OR2L14 OR2M2 OR2M7 OR2S2 OR2T1 OR2T4 OR2W1 OR2W3 OR2W3P OR2W8P OR3A1 OR4C12 OR4D2 OR4F11P OR4F17 OR4F18 OR4F19 OR4L1 OR4L2P OR4Q3 OR4Q4 OR51B5 OR51D1 OR51E1 OR51E1P OR51E2 OR51L1 OR52A3P OR52B6 OR56A4 OR5AL1 OR5AL1P OR5AX1 OR5AX1P OR5D14 OR5K1 OR5P3 OR5U1 OR6F1 OR6P1 OR7C1 OR7C4 OR7D4 OR7D4P OR7G2 OR8B3 OR8D1 OR8D3 OR8K3 OR8U8 OR9G1 OR9G5 POGR PSGR PSGR2 TMEM16B	Homo sapiens (human)
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion	A-kinase anchor protein 5 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 8 Glucagon-like peptide 1 receptor Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Inositol 1,4,5-trisphosphate receptor type 2 Inositol 1,4,5-trisphosphate receptor type 3 Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1 Potassium voltage-gated channel subfamily B member 1 Potassium voltage-gated channel subfamily C member 2 Potassium voltage-gated channel subfamily G member 2 Potassium voltage-gated channel subfamily S member 3 Pro-glucagon Rap guanine nucleotide exchange factor 3 Rap guanine nucleotide exchange factor 4 Ras GTPase-activating-like protein IQGAP1 Ras-related protein Rap-1A cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit gamma cAMP-dependent protein kinase type I-alpha regulatory subunit cAMP-dependent protein kinase type I-beta regulatory subunit cAMP-dependent protein kinase type II-alpha regulatory subunit cAMP-dependent protein kinase type II-beta regulatory subunit	O14610 O14775 O43306 O60262 O95398 O95622 P01275 P10644 P13861 P16520 P17612 P22612 P22694 P24588 P31321 P31323 P40145 P43220 P46940 P50150 P50151 P59768 P61952 P62834 P62873 P62879 P63092 P63211 P63215 P63218 Q14571 Q14573 Q14643 Q14721 Q5JWF2 Q8WZA2 Q96PR1 Q9BQ31 Q9HAV0 Q9P2W3 Q9UBI6 Q9UJ96 Q9UK08	ADCY5 ADCY6 ADCY8 AKAP5 AKAP79 CGEF1 CGEF2 EPAC EPAC1 EPAC2 GCG GLP1R GNAS GNAS1 GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 GSP INSP3R1 IQGAP1 ITPR1 ITPR2 ITPR3 KCNB1 KCNC2 KCNF2 KCNG2 KCNS3 KIAA0051 KIAA0422 KREV1 PKACA PKR1 PKR2 PRKACA PRKACB PRKACG PRKAR1 PRKAR1A PRKAR1B PRKAR2 PRKAR2A PRKAR2B RAP1A RAPGEF3 RAPGEF4 TSE1	Homo sapiens (human)
Adrenaline,noradrenaline inhibits insulin secretion	Adenylate cyclase type 5 Adenylate cyclase type 6 Alpha-2A adrenergic receptor Alpha-2C adrenergic receptor Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(i) subunit alpha-1 Guanine nucleotide-binding protein G(i) subunit alpha-2 Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Voltage-dependent L-type calcium channel subunit alpha-1C Voltage-dependent L-type calcium channel subunit alpha-1D Voltage-dependent L-type calcium channel subunit beta-2 Voltage-dependent L-type calcium channel subunit beta-3 Voltage-dependent calcium channel subunit alpha-2/delta-2	O14610 O14775 O43306 O60262 O95622 P04899 P08913 P16520 P18825 P50150 P50151 P54284 P59768 P61952 P62873 P62879 P63096 P63211 P63215 P63218 Q01668 Q08289 Q13936 Q9HAV0 Q9NY47 Q9P2W3 Q9UBI6 Q9UK08	ADCY5 ADCY6 ADRA2A ADRA2C ADRA2L2 ADRA2R ADRA2RL2 ADRAR CACH2 CACH3 CACN2 CACN4 CACNA1C CACNA1D CACNA2D2 CACNB2 CACNB3 CACNL1A1 CACNL1A2 CACNLB2 CACNLB3 CCHL1A1 CCHL1A2 GNAI1 GNAI2 GNAI2B GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 KIAA0422 KIAA0558 MYSB	Homo sapiens (human)
NGF-independant TRKA activation	Adenosine receptor A2a BDNF/NT-3 growth factors receptor High affinity nerve growth factor receptor Pituitary adenylate cyclase-activating polypeptide type I receptor Pituitary adenylate cyclase-activating polypeptide	P04629 P18509 P29274 P41586 Q16620	ADCYAP1 ADCYAP1R1 ADORA2 ADORA2A MTC NTRK1 NTRK2 TRK TRKA TRKB	Homo sapiens (human)
Glucagon-type ligand receptors	Gastric inhibitory polypeptide receptor Gastric inhibitory polypeptide Glucagon receptor Glucagon-like peptide 1 receptor Glucagon-like peptide 2 receptor Growth hormone-releasing hormone receptor Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Pituitary adenylate cyclase-activating polypeptide type I receptor Pituitary adenylate cyclase-activating polypeptide Pro-glucagon Secretin receptor Secretin Somatoliberin VIP peptides Vasoactive intestinal polypeptide receptor 1 Vasoactive intestinal polypeptide receptor 2	O14610 O14775 O60262 O95838 P01275 P01282 P01286 P09681 P09683 P16520 P18509 P32241 P41586 P41587 P43220 P47871 P47872 P48546 P50150 P50151 P59768 P61952 P62873 P62879 P63092 P63211 P63215 P63218 Q02643 Q5JWF2 Q9HAV0 Q9P2W3 Q9UBI6 Q9UK08	ADCYAP1 ADCYAP1R1 GCG GCGR GHRF GHRH GHRHR GIP GIPR GLP1R GLP2R GNAS GNAS1 GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 GSP SCT SCTR VIP VIP2R VIPR1 VIPR2	Homo sapiens (human)
Caspase-mediated cleavage of cytoskeletal proteins	Alpha-adducin Caspase-3 Caspase-6 Caspase-7 Caspase-8 Drebrin-like protein Gelsolin Growth arrest-specific protein 2 Microtubule-associated protein tau Plectin Spectrin alpha chain, non-erythrocytic 1 Vimentin	O43903 P06396 P08670 P10636 P35611 P42574 P55210 P55212 Q13813 Q14790 Q15149 Q9UJU6	ADD1 ADDA CASP3 CASP6 CASP7 CASP8 CMAP CPP32 DBNL GAS2 GSN MAPT MAPTL MCH2 MCH3 MCH5 MTBT1 NEAS PLEC PLEC1 SH3P7 SPTA2 SPTAN1 TAU VIM	Homo sapiens (human)
Purine ribonucleoside monophosphate biosynthesis	Adenylosuccinate lyase Adenylosuccinate synthetase isozyme 1 Adenylosuccinate synthetase isozyme 2 Amidophosphoribosyltransferase Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase Bifunctional purine biosynthesis protein ATIC GMP synthase [glutamine-hydrolyzing] Inosine-5'-monophosphate dehydrogenase 1 Inosine-5'-monophosphate dehydrogenase 2 Phosphoribosylformylglycinamidine synthase Trifunctional purine biosynthetic protein adenosine-3	O15067 P12268 P20839 P22102 P22234 P30520 P30566 P31939 P49915 Q06203 Q8N142	ADE2 ADSL ADSS ADSS1 ADSS2 ADSSL1 AIRC AMPS ATIC GART GMPS GPAT IMPD1 IMPD2 IMPDH1 IMPDH2 KIAA0361 PAICS PAIS PFAS PGFT PPAT PRGS PURH	Homo sapiens (human)
Lipophagy	5'-AMP-activated protein kinase catalytic subunit alpha-2 5'-AMP-activated protein kinase subunit beta-1 5'-AMP-activated protein kinase subunit beta-2 5'-AMP-activated protein kinase subunit gamma-1 5'-AMP-activated protein kinase subunit gamma-2 5'-AMP-activated protein kinase subunit gamma-3 Heat shock cognate 71 kDa protein Perilipin-2 Perilipin-3	O43741 O60664 P11142 P54619 P54646 Q99541 Q9UGI9 Q9UGJ0 Q9Y478	ADFP AMPK AMPK2 AMPKG3 HSC70 HSP73 HSPA10 HSPA8 M6PRBP1 PLIN2 PLIN3 PRKAA2 PRKAB1 PRKAB2 PRKAG1 PRKAG2 PRKAG3 TIP47	Homo sapiens (human)
Class B/2 (Secretin family receptors)	Adhesion G protein-coupled receptor E1 Adhesion G protein-coupled receptor E2 Adhesion G protein-coupled receptor E3 Adhesion G protein-coupled receptor E5 Complement decay-accelerating factor Corticoliberin Corticotropin-releasing factor receptor 1 Corticotropin-releasing factor-binding protein Desert hedgehog protein Frizzled-10 Frizzled-1 Frizzled-2 Frizzled-3 Frizzled-4 Frizzled-5 Frizzled-6 Frizzled-7 Frizzled-8 Frizzled-9 Indian hedgehog protein Parathyroid hormone 2 receptor Parathyroid hormone-related protein Parathyroid hormone/parathyroid hormone-related peptide receptor Parathyroid hormone Protein Wnt-10a Protein Wnt-10b Protein Wnt-11 Protein Wnt-16 Protein Wnt-2 Protein Wnt-2b Protein Wnt-3a Protein Wnt-4 Protein Wnt-5a Protein Wnt-6 Protein Wnt-7a Protein Wnt-7b Protein Wnt-8a Protein Wnt-8b Protein Wnt-9a Protein Wnt-9b Protein patched homolog 1 Protein patched homolog 2 Protein smoothened Proto-oncogene Wnt-1 Proto-oncogene Wnt-3 Sonic hedgehog protein Tuberoinfundibular peptide of 39 residues Urocortin-2 Urocortin-3 Urocortin	O00144 O00744 O00755 O14904 O14905 O43323 O60353 O75084 O96014 P01270 P04628 P06850 P08174 P09544 P12272 P24387 P34998 P41221 P48960 P49190 P55089 P56703 P56704 P56705 P56706 Q03431 Q13467 Q13635 Q14246 Q14332 Q14623 Q15465 Q93097 Q93098 Q969E3 Q96A98 Q96RP3 Q99835 Q9BY15 Q9GZT5 Q9H1J5 Q9H461 Q9NPG1 Q9UBV4 Q9UHX3 Q9ULV1 Q9ULW2 Q9UP38 Q9Y6C5 Q9Y6F9	ADGRE1 ADGRE2 ADGRE3 ADGRE5 C2orf31 CD55 CD97 CR CRFBP CRFR CRFR1 CRH CRHBP CRHR CRHR1 DAF DHH EMR1 EMR2 EMR3 FZD1 FZD10 FZD2 FZD3 FZD4 FZD5 FZD6 FZD7 FZD8 FZD9 IHH INT1 INT1L1 INT4 IRP PTCH PTCH1 PTCH2 PTH PTH1R PTH2 PTH2R PTHLH PTHR PTHR1 PTHR2 PTHRP SHH SMO SMOH SPC SRP TIP39 TIPF39 TM7LN3 UCN UCN2 UCN3 URP WNT1 WNT10A WNT10B WNT11 WNT12 WNT13 WNT14 WNT14B WNT15 WNT16 WNT2 WNT2B WNT3 WNT3A WNT4 WNT5A WNT6 WNT7A WNT7B WNT8A WNT8B WNT8D WNT9A WNT9B	Homo sapiens (human)
RA biosynthesis pathway	2-aminomuconic semialdehyde dehydrogenase Alcohol dehydrogenase 1A Alcohol dehydrogenase 1C Aldehyde dehydrogenase 1A1 Aldo-keto reductase family 1 member C3 All-trans-retinol dehydrogenase [NAD(+)] ADH4 Cellular retinoic acid-binding protein 1 Cytochrome P450 26A1 Cytochrome P450 26B1 Cytochrome P450 26C1 Dehydrogenase/reductase SDR family member 4 Dehydrogenase/reductase SDR family member 9 Epidermal retinol dehydrogenase 2 Retinal dehydrogenase 2 Retinaldehyde dehydrogenase 3 Retinol dehydrogenase 10 Retinol dehydrogenase 11 Retinol dehydrogenase 13 Retinol dehydrogenase 14 Retinol dehydrogenase 16 Retinol dehydrogenase 5 Short-chain dehydrogenase/reductase 3	O43174 O75452 O75911 O94788 P00326 P00352 P07327 P08319 P29762 P42330 P47895 Q6V0L0 Q8IZV5 Q8N3Y7 Q8NBN7 Q8TC12 Q92781 Q9BPW9 Q9BTZ2 Q9H2A2 Q9HBH5 Q9NR63	ADH1 ADH1A ADH1C ADH2 ADH3 ADH4 AKR1C3 ALDC ALDH1 ALDH12 ALDH1A1 ALDH1A2 ALDH1A3 ALDH6 ALDH8A1 ARSDR1 CRABP1 CYP26 CYP26A1 CYP26A2 CYP26B1 CYP26C1 DDH1 DHRS3 DHRS4 DHRS9 HSD17B5 HSD17B9 KIAA0119 P450RAI1 P450RAI2 PAN2 PGFS PSDR1 PUMB1 RALDH2 RBP5 RDH1 RDH10 RDH11 RDH13 RDH14 RDH15 RDH16 RDH17 RDH5 RDHE2 RODH4 SDR16C1 SDR16C4 SDR16C5 SDR25C2 SDR7C1 SDR7C3 SDR7C4 SDR9C4 SDR9C5 SDR9C8	Homo sapiens (human)
Interconversion of 2-oxoglutarate and 2-hydroxyglutarate	D-2-hydroxyglutarate dehydrogenase, mitochondrial Hydroxyacid-oxoacid transhydrogenase, mitochondrial L-2-hydroxyglutarate dehydrogenase, mitochondrial	Q8IWW8 Q8N465 Q9H9P8	ADHFE1 C14orf160 D2HGD D2HGDH L2HGDH	Homo sapiens (human)
Vasopressin-like receptors	Oxytocin receptor Oxytocin-neurophysin 1 Vasopressin V1a receptor Vasopressin V1b receptor Vasopressin V2 receptor Vasopressin-neurophysin 2-copeptin	P01178 P01185 P30518 P30559 P37288 P47901	ADHR ARVP AVP AVPR1 AVPR1A AVPR1B AVPR2 AVPR3 DIR DIR3 OT OXT OXTR V2R VP VPR3	Homo sapiens (human)
Defective AVP does not bind AVPR2 and causes neurohypophyseal diabetes insipidus (NDI)	Vasopressin V2 receptor Vasopressin-neurophysin 2-copeptin	P01185 P30518	ADHR ARVP AVP AVPR2 DIR DIR3 V2R VP	Homo sapiens (human)
Methionine salvage pathway	Acireductone dioxygenase Aspartate aminotransferase, cytoplasmic Enolase-phosphatase E1 Methylthioribose-1-phosphate isomerase Methylthioribulose-1-phosphate dehydratase S-methyl-5'-thioadenosine phosphorylase	P17174 Q13126 Q96GX9 Q9BV20 Q9BV57 Q9UHY7	ADI1 APIP ENOPH1 GOT1 MASA MRDI MRI1 MSAP MTAP MTCBP1	Homo sapiens (human)
Interconversion of nucleotide di- and triphosphates	Adenylate kinase 2, mitochondrial Adenylate kinase 4, mitochondrial Adenylate kinase 7 Adenylate kinase 8 Adenylate kinase 9 Adenylate kinase isoenzyme 1 Adenylate kinase isoenzyme 5 Adenylate kinase isoenzyme 6 CTP synthase 1 CTP synthase 2 Deoxycytidylate deaminase Glutaredoxin-1 Guanylate kinase NAD(P)H pyrophosphatase NUDT13, mitochondrial Nucleoside diphosphate kinase 3 Nucleoside diphosphate kinase A Nucleoside diphosphate kinase B Nucleoside diphosphate kinase, mitochondrial Putative nucleoside diphosphate kinase Ribonucleoside-diphosphate reductase large subunit Ribonucleoside-diphosphate reductase subunit M2 B Ribonucleoside-diphosphate reductase subunit M2 Thioredoxin reductase 1, cytoplasmic Thioredoxin Thymidylate kinase Thymidylate synthase UMP-CMP kinase dCTP pyrophosphatase 1	O00746 O60361 P00568 P04818 P10599 P15531 P17812 P22392 P23919 P23921 P27144 P30085 P31350 P32321 P35754 P54819 Q13232 Q16774 Q16881 Q5TCS8 Q7LG56 Q86X67 Q96M32 Q96MA6 Q9H773 Q9NRF8 Q9Y3D8 Q9Y6K8	ADK2 AK1 AK2 AK3 AK3L1 AK4 AK5 AK6 AK7 AK8 AK9 AKD1 AKD2 C6orf199 C6orf224 C9orf98 CDC8 CINAP CMK CMPK CMPK1 CTPS CTPS1 CTPS2 DCTD DCTPP1 DTYMK GLRX GMK GMPK GRIM12 GRX GUK1 KDRF NDPKA NM23 NM23B NM23D NME1 NME2 NME2P1 NME3 NME4 NUDT13 P53R2 RR1 RR2 RRM1 RRM2 RRM2B TMPK TRDX TRX TRX1 TS TXN TXNRD1 TYMK TYMS UCK UMK UMPK XTP3TPA	Homo sapiens (human)
Calcitonin-like ligand receptors	Calcitonin gene-related peptide 1 Calcitonin gene-related peptide 2 Calcitonin gene-related peptide type 1 receptor Calcitonin receptor Calcitonin Islet amyloid polypeptide Pro-adrenomedullin Protein ADM2 Receptor activity-modifying protein 1 Receptor activity-modifying protein 2 Receptor activity-modifying protein 3	O60894 O60895 O60896 P01258 P06881 P10092 P10997 P30988 P35318 Q16602 Q7Z4H4	ADM ADM2 AM AM2 CALC1 CALC2 CALCA CALCB CALCR CALCRL CGRPR IAPP RAMP1 RAMP2 RAMP3	Homo sapiens (human)
FGFR1c ligand binding and activation	Anosmin-1 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 4 Fibroblast growth factor 6 Fibroblast growth factor 9 PDZ domain-containing protein GIPC1 Transforming growth factor beta receptor type 3	O14908 P05230 P08620 P09038 P10767 P23352 P31371 Q03167 Q9GZV9 Q9NP95	ADMLX ANOS1 C19orf3 FGF1 FGF2 FGF20 FGF23 FGF4 FGF6 FGF9 FGFA FGFB GIPC GIPC1 HST HST2 HSTF1 HSTF2 HYPF KAL KAL1 KALIG1 KS3 RGS19IP1 TGFBR3	Homo sapiens (human)
Negative regulation of FGFR1 signaling	Anosmin-1 E3 ubiquitin-protein ligase CBL Fibroblast growth factor 10 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 22 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor 4 Fibroblast growth factor 6 Fibroblast growth factor 9 Fibroblast growth factor receptor substrate 2 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Polyubiquitin-B Polyubiquitin-C Tyrosine-protein phosphatase non-receptor type 11 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O15520 P05230 P08620 P09038 P0CG47 P0CG48 P10767 P11487 P22681 P23352 P27361 P28482 P31371 P62979 P62987 Q06124 Q8WU20 Q9GZV9 Q9HCT0 Q9NP95	ADMLX ANOS1 CBL CBL2 ERK1 ERK2 FGF1 FGF10 FGF2 FGF20 FGF22 FGF23 FGF3 FGF4 FGF6 FGF9 FGFA FGFB FRS2 HST HST2 HSTF1 HSTF2 HYPF INT2 KAL KAL1 KALIG1 KS3 MAPK1 MAPK3 PRKM1 PRKM2 PRKM3 PTP2C PTPN11 RNF55 RPS27A SHPTP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Homo sapiens (human)
Degradation of cysteine and homocysteine	2-aminoethanethiol dioxygenase 3-mercaptopyruvate sulfurtransferase Acidic amino acid decarboxylase GADL1 Aspartate aminotransferase, mitochondrial Cystathionine gamma-lyase Cysteine dioxygenase type 1 Cysteine sulfinic acid decarboxylase Flavin-containing monooxygenase 1 Thioredoxin, mitochondrial Thiosulfate sulfurtransferase	P00505 P25325 P32929 Q01740 Q16762 Q16878 Q6ZQY3 Q96SZ5 Q99757 Q9Y600	ADO C10orf22 CDO1 CSAD CSD CTH FMO1 GADL1 GOT2 KYAT4 MPST TRX2 TST TST2 TXN2	Homo sapiens (human)
Adenosine P1 receptors	Adenosine receptor A1 Adenosine receptor A2a Adenosine receptor A2b Adenosine receptor A3	P0DMS8 P29274 P29275 P30542	ADORA1 ADORA2 ADORA2A ADORA2B ADORA3	Homo sapiens (human)

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