GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **1401 - 1425** of **2090** in total

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Pathway Name	Protein Name	UniProt ID ▼	Gene Symbol	Organism
Mitochondrial protein degradation	2-oxoglutarate dehydrogenase complex component E1 3-hydroxyacyl-CoA dehydrogenase type-2 3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial 5-aminolevulinate synthase, non-specific, mitochondrial 60 kDa heat shock protein, mitochondrial ADP/ATP translocase 2 ADP/ATP translocase 3 ATP synthase subunit O, mitochondrial ATP synthase subunit a ATP synthase subunit alpha, mitochondrial ATP synthase subunit beta, mitochondrial ATP synthase subunit d, mitochondrial ATP synthase subunit g, mitochondrial ATP synthase subunit gamma, mitochondrial ATP synthase-coupling factor 6, mitochondrial ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial ATP-dependent Clp protease proteolytic subunit, mitochondrial ATP-dependent zinc metalloprotease YME1L1 Acetyl-CoA acetyltransferase, mitochondrial Aconitate hydratase, mitochondrial Acyl-coenzyme A thioesterase 2, mitochondrial Aldehyde dehydrogenase X, mitochondrial Aldehyde dehydrogenase, mitochondrial Arginase-2, mitochondrial Calcium uptake protein 2, mitochondrial Citrate synthase, mitochondrial Coiled-coil-helix-coiled-coil-helix domain-containing protein 2 Cytochrome b-c1 complex subunit 2, mitochondrial Cytochrome b-c1 complex subunit 8 Cytochrome c oxidase subunit 1 Cytochrome c oxidase subunit 2 Cytochrome c oxidase subunit 4 isoform 1, mitochondrial Cytochrome c oxidase subunit 5A, mitochondrial Cytochrome c oxidase subunit 5B, mitochondrial D-beta-hydroxybutyrate dehydrogenase, mitochondrial Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial Delta-1-pyrroline-5-carboxylate synthase Dihydrolipoyl dehydrogenase, mitochondrial Dynamin-like GTPase OPA1, mitochondrial Enoyl-CoA delta isomerase 1, mitochondrial Essential MCU regulator, mitochondrial Ferrochelatase, mitochondrial Fumarate hydratase, mitochondrial Glutamate dehydrogenase 1, mitochondrial Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial Hydroxymethylglutaryl-CoA synthase, mitochondrial Isobutyryl-CoA dehydrogenase, mitochondrial Isocitrate dehydrogenase [NADP], mitochondrial Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial Isoleucine--tRNA ligase, mitochondrial Large ribosomal subunit protein bL12m Large ribosomal subunit protein bL32m Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial Lon protease homolog, mitochondrial Malate dehydrogenase, mitochondrial Metalloendopeptidase OMA1, mitochondrial Mitochondrial import inner membrane translocase subunit Tim10 Mitochondrial import inner membrane translocase subunit Tim17-A Mitochondrial import inner membrane translocase subunit Tim22 Mitochondrial import inner membrane translocase subunit Tim9 Mitochondrial inner membrane m-AAA protease component AFG3L2 Mitochondrial inner membrane m-AAA protease component paraplegin Mitochondrial-processing peptidase subunit alpha NAD kinase 2, mitochondrial NAD-dependent malic enzyme, mitochondrial NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial NADH-ubiquinone oxidoreductase chain 1 NADH-ubiquinone oxidoreductase chain 2 NADH-ubiquinone oxidoreductase chain 5 NADH-ubiquinone oxidoreductase chain 6 PRELI domain-containing protein 1, mitochondrial Probable D-lactate dehydrogenase, mitochondrial Propionyl-CoA carboxylase beta chain, mitochondrial Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial Pyruvate dehydrogenase E1 component subunit beta, mitochondrial Serine hydroxymethyltransferase, mitochondrial Serine protease HTRA2, mitochondrial Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial Single-stranded DNA-binding protein, mitochondrial Small ribosomal subunit protein uS10m Small ribosomal subunit protein uS2m StAR-related lipid transfer protein 7, mitochondrial Steroidogenic acute regulatory protein, mitochondrial Stress-70 protein, mitochondrial Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial Succinyl-CoA TP53-regulated inhibitor of apoptosis 1 Transcription factor A, mitochondrial Twinkle mtDNA helicase [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial cAMP-dependent protein kinase catalytic subunit alpha	O14949 O43464 O43678 O43715 O60313 O75390 O75489 O75947 O75964 O76031 O95139 P00367 P00395 P00403 P00846 P03886 P03891 P03915 P03923 P05091 P05141 P05166 P06576 P07954 P08559 P09622 P10606 P10809 P11177 P11182 P12236 P13073 P13196 P17612 P18859 P20674 P22695 P22830 P23368 P24752 P25705 P28331 P30837 P34897 P36542 P36776 P38646 P40926 P42126 P45954 P48047 P48735 P49675 P49753 P49821 P50213 P52815 P54868 P54886 P55809 P56181 P62072 P78540 P82664 Q00059 Q02218 Q02338 Q04837 Q10713 Q13011 Q15118 Q16740 Q16836 Q4G0N4 Q86WU2 Q8IYU8 Q96E52 Q96I99 Q96RR1 Q96TA2 Q99595 Q99714 Q99798 Q9BYC8 Q9H4I9 Q9NQZ5 Q9NSE4 Q9NWU1 Q9P0J0 Q9UKU7 Q9UQ90 Q9Y255 Q9Y399 Q9Y4W6 Q9Y584 Q9Y5J7 Q9Y6H1	15E1.1 AAC2 AAC3 ACAD8 ACADSB ACAT ACAT1 ACO2 ACOT2 AFG3L2 ALAS1 ALAS3 ALASH ALDH18A1 ALDH1B1 ALDH2 ALDH5 ALDHX ALDM ANT2 ANT3 ARC42 ARG2 ATP5A ATP5A1 ATP5AL2 ATP5B ATP5C ATP5C1 ATP5CL1 ATP5F1A ATP5F1B ATP5F1C ATP5H ATP5J ATP5L ATP5MG ATP5O ATP5PD ATP5PF ATP5PO ATP6 ATPASE6 ATPM ATPMB ATPO ATPSB BCATE2 BCKDHE2 BDH BDH1 C10orf2 C22orf32 C5orf33 C7orf17 CAR CHCHD2 CLPP CLPX CMAR COI COII COX2 COX4 COX4I1 COX5A COX5B COXI COXII CS DBT DCI DLD ECH1 ECI1 EFHA1 EMRE ERAB FECH FH FTSH1 GCSL GLUD GLUD1 GRIM19 GRP75 GSAS GTT1 HAD HAD1 HADH HADH2 HADHSC HMGCS2 HSD17B10 HSP60 HSPA9 HSPA9B HSPD1 HTRA2 IARS2 IBD IDH2 IDH3A INPP5E KIAA0123 KIAA0567 LAD LDHD LONP1 MAT MDH2 ME2 MICU2 MIMT17 MNADK MPPA MPRP1 MRPL12 MRPL32 MRPL7 MRPP2 MRPS10 MRPS2 MT-ATP6 MT-CO1 MT-CO2 MT-ND1 MT-ND2 MT-ND5 MT-ND6 MTATP6 MTCO1 MTCO2 MTND1 MTND2 MTND5 MTND6 NADH1 NADH2 NADH5 NADH6 NADK2 NADKD1 ND1 ND2 ND5 ND6 NDUFA13 NDUFA2 NDUFB6 NDUFS1 NDUFS3 NDUFV1 NDUFV3 OGDH OMA1 OMI OPA1 OXCT OXCT1 OXSM P5CS PCCB PDHA1 PDHB PDHK1 PDK1 PEO1 PGN PHE1A PHE1B PHE3 PKACA PMPCA PRELI PRELID1 PRKACA PRSS15 PRSS25 PTE2 PTE2A PYCS RPML12 SCHAD SCOT SDR5C1 SDR9C1 SHMT2 SLC25A5 SLC25A6 SMDT1 SPG7 SSBP SSBP1 STAR STARD1 STARD7 SUCLG2 TCF6 TCF6L2 TEX4 TFAM TIM10 TIM17 TIM17A TIM22 TIM9 TIM9A TIMM10 TIMM17 TIMM17A TIMM22 TIMM9 TIMM9A TRIAP1 TWNK UQCRC2 UQCRQ UQOR1 XH98G2 YME1L YME1L1 mt-HSP70	Homo sapiens (human)
Transcriptional and post-translational regulation of MITF-M expression and activity	Adenosine 5'-monophosphoramidase HINT1 Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 Arginine--tRNA ligase, cytoplasmic Aspartate--tRNA ligase, cytoplasmic Bifunctional glutamate/proline--tRNA ligase CREB-binding protein Catenin beta-1 Eukaryotic translation elongation factor 1 epsilon-1 Exportin-1 Forkhead box protein D3 Glutamine--tRNA ligase Glycogen synthase kinase-3 beta Homeobox protein aristaless-like 3 Isoleucine--tRNA ligase, cytoplasmic Leucine--tRNA ligase, cytoplasmic Lymphoid enhancer-binding factor 1 Lysine--tRNA ligase Mast/stem cell growth factor receptor Kit Melanocortin receptor 3 Melanocortin receptor 4 Melanocortin receptor 5 Melanocyte-stimulating hormone receptor Methionine--tRNA ligase, cytoplasmic Microphthalmia-associated transcription factor Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 POU domain, class 3, transcription factor 2 Paired box protein Pax-3 Pro-opiomelanocortin Protein Wnt-3a Ribosomal protein S6 kinase alpha-1 Transcription factor E3 Transcription factor EB Transcription factor EC Transcription factor SOX-10 Transcription factor SOX-2	O14948 O14980 O43324 O75030 O95076 P01189 P07814 P10721 P14868 P19484 P19532 P20265 P23760 P27361 P28482 P32245 P33032 P35222 P41252 P41968 P47897 P48431 P49773 P49841 P54136 P56192 P56693 P56704 Q01726 Q12904 Q13155 Q15046 Q15418 Q92793 Q9P2J5 Q9UJU2 Q9UJU5	AIMP1 AIMP2 AIMP3 ALX3 BHLHE32 BHLHE33 BHLHE34 BHLHE35 BRN2 CBP CREBBP CRM1 CTNNB CTNNB1 DARS DARS1 EEF1E1 EMAP2 EPRS EPRS1 ERK1 ERK2 FOXD3 GLNS GSK3B HFH2 HINT HINT1 HUP2 IARS IARS1 JTV1 KARS KARS1 KIAA0070 KIAA1352 KIT LARS LARS1 LEF1 MAPK1 MAPK3 MAPKAPK1A MARS MARS1 MC1R MC3R MC4R MC5R MITF MSHR OCT7 OTF7 P18 PARS PAX3 PKCI1 POMC POU3F2 PRKCNH1 PRKM1 PRKM2 PRKM3 QARS QARS1 QPRS RARS RARS1 RPS6KA1 RSK1 SCFR SCYE1 SOX10 SOX2 TCFEC TFE3 TFEB TFEC TFECL WNT3A XPO1	Homo sapiens (human)
Inhibition of Signaling by Overexpressed EGFR	Amphiregulin Epidermal growth factor receptor Epigen Pro-epidermal growth factor Probetacellulin Proepiregulin Proheparin-binding EGF-like growth factor Protransforming growth factor alpha	O14944 P00533 P01133 P01135 P15514 P35070 Q6UW88 Q99075	AREG AREGB BTC DTR DTS EGF EGFR EPGN ERBB ERBB1 EREG HBEGF HEGFL HER1 SDGF TGFA	Homo sapiens (human)
EGFR interacts with phospholipase C-gamma	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Amphiregulin Epidermal growth factor receptor Epigen Pro-epidermal growth factor Probetacellulin Proepiregulin Proheparin-binding EGF-like growth factor Protransforming growth factor alpha	O14944 P00533 P01133 P01135 P15514 P19174 P35070 Q6UW88 Q99075	AREG AREGB BTC DTR DTS EGF EGFR EPGN ERBB ERBB1 EREG HBEGF HEGFL HER1 PLC1 PLCG1 SDGF TGFA	Homo sapiens (human)
GAB1 signalosome	Amphiregulin Epidermal growth factor receptor Epigen GRB2-associated-binding protein 1 Paxillin Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 Pro-epidermal growth factor Probetacellulin Proepiregulin Proheparin-binding EGF-like growth factor Proto-oncogene tyrosine-protein kinase Src Protransforming growth factor alpha Tyrosine-protein kinase CSK Tyrosine-protein phosphatase non-receptor type 11	O14944 P00533 P01133 P01135 P12931 P15514 P27986 P35070 P41240 P42336 P49023 Q06124 Q13480 Q6UW88 Q99075 Q9NWQ8	AREG AREGB BTC CBP CSK DTR DTS EGF EGFR EPGN ERBB ERBB1 EREG GAB1 GRB1 HBEGF HEGFL HER1 PAG PAG1 PIK3CA PIK3R1 PTP2C PTPN11 PXN SDGF SHPTP2 SRC SRC1 TGFA	Homo sapiens (human)
GRB2 events in EGFR signaling	Amphiregulin Epidermal growth factor receptor Epigen GTPase HRas GTPase NRas Pro-epidermal growth factor Probetacellulin Proepiregulin Proheparin-binding EGF-like growth factor Protransforming growth factor alpha Son of sevenless homolog 1	O14944 P00533 P01111 P01112 P01133 P01135 P15514 P35070 Q07889 Q6UW88 Q99075	AREG AREGB BTC DTR DTS EGF EGFR EPGN ERBB ERBB1 EREG HBEGF HEGFL HER1 HRAS HRAS1 NRAS SDGF SOS1 TGFA	Homo sapiens (human)
SHC1 events in EGFR signaling	Amphiregulin Epidermal growth factor receptor Epigen GTPase HRas GTPase NRas Pro-epidermal growth factor Probetacellulin Proepiregulin Proheparin-binding EGF-like growth factor Protransforming growth factor alpha SHC-transforming protein 1 Son of sevenless homolog 1	O14944 P00533 P01111 P01112 P01133 P01135 P15514 P29353 P35070 Q07889 Q6UW88 Q99075	AREG AREGB BTC DTR DTS EGF EGFR EPGN ERBB ERBB1 EREG HBEGF HEGFL HER1 HRAS HRAS1 NRAS SDGF SHC SHC1 SHCA SOS1 TGFA	Homo sapiens (human)
Estrogen-dependent nuclear events downstream of ESR-membrane signaling	Amphiregulin Apoptosis regulator Bcl-2 Cyclin-dependent kinase inhibitor 1B ETS domain-containing protein Elk-1 Epidermal growth factor receptor Epigen Exportin-1 Focal adhesion kinase 1 Forkhead box protein O3 G1/S-specific cyclin-D1 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Pro-epidermal growth factor Probetacellulin Proepiregulin Proheparin-binding EGF-like growth factor Protein c-Fos Protransforming growth factor alpha RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Serine/threonine-protein kinase Kist Serum response factor	O14944 O14980 O43524 P00533 P01100 P01133 P01135 P10415 P11831 P15514 P19419 P24385 P27361 P28482 P31749 P31751 P35070 P46527 Q05397 Q6UW88 Q8TAS1 Q99075 Q9Y243	AKT1 AKT2 AKT3 AREG AREGB BCL1 BCL2 BTC CCND1 CDKN1B CRM1 DTR DTS EGF EGFR ELK1 EPGN ERBB ERBB1 EREG ERK1 ERK2 FAK FAK1 FKHRL1 FOS FOXO3 FOXO3A G0S7 HBEGF HEGFL HER1 KIP1 KIS KIST MAPK1 MAPK3 PKB PKBG PRAD1 PRKM1 PRKM2 PRKM3 PTK2 RAC SDGF SRF TGFA UHMK1 XPO1 p27	Homo sapiens (human)
EGFR downregulation	Amphiregulin Cell division control protein 42 homolog E3 ubiquitin-protein ligase CBL Endophilin-A1 Endophilin-A2 Endophilin-A3 Epidermal growth factor receptor substrate 15-like 1 Epidermal growth factor receptor substrate 15 Epidermal growth factor receptor Epigen Epsin-1 Hepatocyte growth factor-regulated tyrosine kinase substrate Polyubiquitin-B Polyubiquitin-C Pro-epidermal growth factor Probetacellulin Proepiregulin Proheparin-binding EGF-like growth factor Protein sprouty homolog 1 Protein sprouty homolog 2 Protransforming growth factor alpha Receptor-type tyrosine-protein phosphatase kappa Rho guanine nucleotide exchange factor 7 SH3 domain-containing kinase-binding protein 1 Signal transducing adapter molecule 1 Signal transducing adapter molecule 2 Tyrosine-protein phosphatase non-receptor type 12 Tyrosine-protein phosphatase non-receptor type 3 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O14944 O14964 O43597 O43609 O75886 P00533 P01133 P01135 P0CG47 P0CG48 P15514 P22681 P26045 P35070 P42566 P60953 P62979 P62987 Q05209 Q14155 Q15262 Q6UW88 Q92783 Q96B97 Q99075 Q99961 Q99962 Q99963 Q9UBC2 Q9Y6I3	AF1P AREG AREGB ARHGEF7 BTC CBL CBL2 CDC42 CIN85 CNSA1 CNSA2 CNSA3 COOL1 DTR DTS EGF EGFR EPGN EPN1 EPS15 EPS15L1 EPS15R ERBB ERBB1 EREG HBEGF HBP HEGFL HER1 HGS HRS KIAA0142 P85SPR PAK3BP PIXB PTPH1 PTPK PTPN12 PTPN3 PTPRK RNF55 RPS27A SDGF SH3D2A SH3D2B SH3D2C SH3GL1 SH3GL2 SH3GL3 SH3KBP1 SPRY1 SPRY2 STAM STAM1 STAM2 TGFA UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Homo sapiens (human)
Synthesis of PG	5'-3' exonuclease PLD3 5'-3' exonuclease PLD4 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial Mitochondrial cardiolipin hydrolase Phosphatidate cytidylyltransferase 2 Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 Phospholipase D1 Phospholipase D2	O14939 O95674 Q13393 Q32NB8 Q8IV08 Q8N2A8 Q8WUK0 Q96BZ4	C14orf175 CDS2 MOSP PGS1 PLD1 PLD2 PLD3 PLD4 PLD6 PLIP PTPMT1	Homo sapiens (human)
Synthesis of PA	1-acyl-sn-glycerol-3-phosphate acyltransferase alpha 1-acyl-sn-glycerol-3-phosphate acyltransferase beta 1-acyl-sn-glycerol-3-phosphate acyltransferase delta 1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma Cytosolic phospholipase A2 beta Cytosolic phospholipase A2 delta Cytosolic phospholipase A2 Dihydroxyacetone phosphate acyltransferase Glycerol-3-phosphate acyltransferase 1, mitochondrial Glycerol-3-phosphate acyltransferase 2, mitochondrial Glycerol-3-phosphate acyltransferase 3 Glycerol-3-phosphate acyltransferase 4 Glycerol-3-phosphate dehydrogenase 1-like protein Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic Glycerol-3-phosphate dehydrogenase, mitochondrial Group 10 secretory phospholipase A2 Group IID secretory phospholipase A2 Group IIE secretory phospholipase A2 Group IIF secretory phospholipase A2 Group XIIA secretory phospholipase A2 Intestinal-type alkaline phosphatase Lipase member H Lipase member I Lysocardiolipin acyltransferase 1 Lysophosphatidic acid phosphatase type 6 Lysophosphatidylcholine acyltransferase 1 Lysophospholipid acyltransferase LPCAT4 Mitochondrial cardiolipin hydrolase Mitoguardin 1 Mitoguardin 2 Phospholipase A2 group V Phospholipase A2, membrane associated Phospholipase A2 Phospholipase D1 Phospholipase D2 Phospholipase DDHD1 Phospholipase DDHD2 Secretory phospholipase A2 receptor	O14939 O15120 O15228 O15496 O94830 P04054 P09923 P0C869 P14555 P21695 P39877 P43304 P47712 Q13018 Q13393 Q53EU6 Q643R3 Q6NUI2 Q6UWP7 Q6XZB0 Q7L4E1 Q86UL3 Q86XP0 Q8N2A8 Q8N335 Q8NAN2 Q8NEL9 Q8NF37 Q8WWY8 Q99943 Q9BZM1 Q9BZM2 Q9HCL2 Q9NPH0 Q9NRZ5 Q9NRZ7 Q9NUQ2 Q9NZK7 Q9UNK4	ACP6 ACPL1 AGPAT1 AGPAT2 AGPAT3 AGPAT4 AGPAT5 AGPAT6 AGPAT7 AGPAT8 AGPAT9 ALCAT1 ALPI AYTL2 AYTL3 C9orf54 CLEC13C CPLA2 DAPAT DDHD1 DDHD2 DHAPAT FAM73A FAM73B G15 GNPAT GPAM GPAT1 GPAT2 GPAT3 GPAT4 GPD1 GPD1L GPD2 KIAA0089 KIAA0725 KIAA1560 KIAA1705 LCLAT1 LIPH LIPI LPAAT3 LPAP LPCAT1 LPCAT4 LPDL LPDLR LPEAT2 LYCAT MAG1 MIGA1 MIGA2 MPAPLA1 PFAAP3 PLA1B PLA2 PLA2A PLA2B PLA2G10 PLA2G12 PLA2G12A PLA2G1B PLA2G2A PLA2G2D PLA2G2E PLA2G2F PLA2G4 PLA2G4A PLA2G4B PLA2G4D PLA2G5 PLA2L PLA2R1 PLD1 PLD2 PLD6 PPLA2 RASF-A SAMWD1 SPLASH TSARG7	Homo sapiens (human)
Syndecan interactions	Alpha-actinin-1 Fibroblast growth factor 2 Integrin alpha-2 Integrin alpha-6 Integrin alpha-V Integrin beta-1 Integrin beta-3 Integrin beta-4 Integrin beta-5 Peripheral plasma membrane protein CASK Protein kinase C alpha type Syndecan-1 Syndecan-2 Syndecan-3 Syndecan-4 Tenascin Thrombospondin-1 Trafficking protein particle complex subunit 4 Transforming growth factor beta-1 proprotein Vitronectin	O14936 O75056 P01137 P04004 P05106 P05556 P06756 P07996 P09038 P12814 P16144 P17252 P17301 P18084 P18827 P23229 P24821 P31431 P34741 Q9Y296	ACTN1 CASK CD49B FGF2 FGFB FNRB GP3A HSPG1 HXB ITGA2 ITGA6 ITGAV ITGB1 ITGB3 ITGB4 ITGB5 KIAA0468 LIN2 MDF2 MSK12 MSK8 PKCA PRKACA PRKCA SBDN SDC SDC1 SDC2 SDC3 SDC4 TGFB TGFB1 THBS1 TNC TRAPPC4 TSP TSP1 VNRA VTN VTNR	Homo sapiens (human)
Termination of translesion DNA synthesis	DNA polymerase delta catalytic subunit DNA polymerase delta subunit 2 DNA polymerase delta subunit 3 DNA polymerase delta subunit 4 DNA polymerase epsilon catalytic subunit A DNA polymerase epsilon subunit 2 DNA polymerase epsilon subunit 3 DNA polymerase epsilon subunit 4 DNA polymerase eta DNA polymerase iota DNA polymerase kappa DNA repair protein REV1 E3 ubiquitin/ISG15 ligase TRIM25 PCNA-associated factor Polyubiquitin-B Polyubiquitin-C Proliferating cell nuclear antigen Replication factor C subunit 1 Replication factor C subunit 2 Replication factor C subunit 3 Replication factor C subunit 4 Replication factor C subunit 5 Replication protein A 14 kDa subunit Replication protein A 32 kDa subunit Replication protein A 70 kDa DNA-binding subunit Ubiquitin carboxyl-terminal hydrolase 10 Ubiquitin carboxyl-terminal hydrolase 43 Ubiquitin-like modifier-activating enzyme 7 Ubiquitin-like protein ISG15 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Ubiquitin/ISG15-conjugating enzyme E2 L6	O14933 P05161 P0CG47 P0CG48 P12004 P15927 P27694 P28340 P35244 P35249 P35250 P35251 P40937 P40938 P41226 P49005 P56282 P62979 P62987 Q07864 Q14258 Q14694 Q15004 Q15054 Q70EL4 Q9HCU8 Q9NR33 Q9NRF9 Q9UBT6 Q9UBZ9 Q9UNA4 Q9Y253	CHRAC17 DINB1 DPE2 EFP G1P2 ISG15 KIAA0039 KIAA0101 KIAA0190 NS5ATP9 PAF PCLAF PCNA POLD POLD1 POLD2 POLD3 POLD4 POLDS POLE POLE1 POLE2 POLE3 POLE4 POLH POLI POLK RAD30 RAD30A RAD30B REPA1 REPA2 REPA3 REV1 REV1L RFC1 RFC140 RFC2 RFC3 RFC4 RFC5 RNF147 RPA1 RPA14 RPA2 RPA3 RPA32 RPA34 RPA70 RPS27A TRIM25 UBA52 UBA7 UBA80 UBB UBC UBCEP1 UBCEP2 UBCH8 UBE1L UBE2 UBE2L6 UCRP USP10 USP43 XPV ZNF147	Homo sapiens (human)
DDX58/IFIH1-mediated induction of interferon-alpha/beta	ATP-dependent RNA helicase DHX58 Antiviral innate immune response receptor RIG-I E3 ISG15--protein ligase HERC5 E3 ubiquitin-protein ligase RNF135 E3 ubiquitin-protein ligase TRIM4 E3 ubiquitin/ISG15 ligase TRIM25 Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Interferon regulatory factor 3 Interferon-induced helicase C domain-containing protein 1 Mitochondrial antiviral-signaling protein Mitochondrial import receptor subunit TOM70 NLR family member X1 Nucleoprotein ORF9b protein Protein NLRC5 Serine/threonine-protein kinase TBK1 Triokinase/FMN cyclase Ubiquitin-like modifier-activating enzyme 7 Ubiquitin-like protein ISG15 Ubiquitin/ISG15-conjugating enzyme E2 L6	O14933 O94826 O95786 P05161 P07900 P08238 P0DTC9 P0DTD2 P41226 Q14258 Q14653 Q3LXA3 Q7Z434 Q86UT6 Q86WI3 Q8IUD6 Q96C10 Q9BYX4 Q9C037 Q9UHD2 Q9UII4	9b CEB1 CEBP1 D11LGP2E DAK DDX58 DHX58 EFP G1P2 HERC5 HSP90A HSP90AA1 HSP90AB1 HSP90B HSPC1 HSPC2 HSPC3 HSPCA HSPCB IFIH1 IPS1 IRF3 ISG15 KIAA0719 KIAA1271 LGP2 MAVS MDA5 N NAK NLRC5 NLRX1 NOD27 NOD4 NOD5 NOD9 RH116 RIGI RNF135 RNF147 RNF87 TBK1 TKFC TOM70 TOMM70 TOMM70A TRIM25 TRIM4 UBA7 UBCH8 UBE1L UBE2 UBE2L6 UCRP VISA ZNF147	Homo sapiens (human)
Negative regulators of RIG-I/MDA5 signaling	Antiviral innate immune response receptor RIG-I Autophagy protein 5 E3 ISG15--protein ligase HERC5 E3 ubiquitin-protein ligase Itchy homolog E3 ubiquitin-protein ligase RNF125 E3 ubiquitin-protein ligase RNF135 E3 ubiquitin-protein ligase RNF216 E3 ubiquitin-protein ligase TRIM4 E3 ubiquitin/ISG15 ligase TRIM25 Inhibitor of nuclear factor kappa-B kinase subunit epsilon Interferon regulatory factor 3 Interferon-induced helicase C domain-containing protein 1 Mitochondrial antiviral-signaling protein NLR family member X1 OTU domain-containing protein 5 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Poly(rC)-binding protein 2 Polyubiquitin-B Polyubiquitin-C Protein NLRC5 Serine/threonine-protein kinase TBK1 TNF receptor-associated factor 3 Tax1-binding protein 1 Tumor necrosis factor alpha-induced protein 3 Ubiquitin carboxyl-terminal hydrolase CYLD Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 D2 Ubiquitin-conjugating enzyme E2 D3 Ubiquitin-conjugating enzyme E2 K Ubiquitin-like modifier-activating enzyme 7 Ubiquitin-like protein ATG12 Ubiquitin-like protein ISG15 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Ubiquitin/ISG15-conjugating enzyme E2 L6	O14933 O94817 O95786 P05161 P0CG47 P0CG48 P21580 P41226 P51668 P61077 P61086 P62837 P62979 P62987 Q13114 Q13526 Q14164 Q14258 Q14653 Q15366 Q7Z434 Q86UT6 Q86VP1 Q86WI3 Q8IUD6 Q96EQ8 Q96G74 Q96J02 Q9BYX4 Q9C037 Q9H1Y0 Q9NQC7 Q9NWF9 Q9UHD2 Q9UII4	APG12 APG12L APG5L ASP ATG12 ATG5 CAP-1 CEB1 CEBP1 CRAF1 CYLD CYLD1 DDX58 EFP G1P2 HERC5 HIP2 IFIH1 IKBKE IKKE IKKI IPS1 IRF3 ISG15 ITCH KIAA0151 KIAA0849 KIAA1271 LIG MAVS MDA5 NAK NLRC5 NLRX1 NOD27 NOD4 NOD5 NOD9 OTUD5 OTUD7C PCBP2 PIN1 PUBC1 RH116 RIGI RNF125 RNF135 RNF147 RNF216 RNF87 RPS27A SFT T6BP TAX1BP1 TBK1 TNFAIP3 TRAF3 TRAFAMN TRIAD3 TRIM25 TRIM4 UBA52 UBA7 UBA80 UBB UBC UBC4 UBC5A UBC5B UBC5C UBCE7IP1 UBCEP1 UBCEP2 UBCH4 UBCH5 UBCH5A UBCH5B UBCH5C UBCH8 UBE1L UBE2 UBE2D1 UBE2D2 UBE2D3 UBE2K UBE2L6 UCRP VISA ZIN ZNF147	Homo sapiens (human)
HATs acetylate histones	Actin, cytoplasmic 1 Actin-like protein 6A Ataxin-7-like protein 3 Ataxin-7 Bromodomain and PHD finger-containing protein 3 Bromodomain-containing protein 1 Bromodomain-containing protein 8 CREB-binding protein Chromatin modification-related protein MEAF6 Circadian locomoter output cycles protein kaput Cyclic AMP-dependent transcription factor ATF-2 Cysteine-rich protein 2-binding protein DNA methyltransferase 1-associated protein 1 E1A-binding protein p400 E3 ubiquitin-protein ligase Jade-2 E3 ubiquitin-protein ligase MSL2 Elongator complex protein 1 Elongator complex protein 2 Elongator complex protein 3 Elongator complex protein 4 Elongator complex protein 5 Elongator complex protein 6 Enhancer of polycomb homolog 1 Histone H2A type 1-A Histone H2A type 1-B/E Histone H2A type 1-C Histone H2A type 1-D Histone H2A type 1-H Histone H2A type 1-J Histone H2A type 1 Histone H2A type 2-A Histone H2A type 2-B Histone H2A type 2-C Histone H2A type 3 Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/F/G/I Histone H2B type 1-D Histone H2B type 1-H Histone H2B type 1-J Histone H2B type 1-K Histone H2B type 1-L Histone H2B type 1-M Histone H2B type 1-N Histone H2B type 1-O Histone H2B type 2-E Histone H2B type 2-F Histone H2B type 3-B Histone H3.1 Histone H3.2 Histone H4 Histone acetyltransferase KAT2A Histone acetyltransferase KAT2B Histone acetyltransferase KAT5 Histone acetyltransferase KAT6A Histone acetyltransferase KAT6B Histone acetyltransferase KAT7 Histone acetyltransferase KAT8 Histone acetyltransferase p300 Histone acetyltransferase type B catalytic subunit Histone deacetylase complex subunit SAP130 Histone-binding protein RBBP7 Host cell factor 1 Inhibitor of growth protein 3 Inhibitor of growth protein 4 Inhibitor of growth protein 5 KAT8 regulatory NSL complex subunit 1 KAT8 regulatory NSL complex subunit 2 KAT8 regulatory NSL complex subunit 3 MAP3K12-binding inhibitory protein 1 MRG/MORF4L-binding protein MSL complex subunit 3 Male-specific lethal 1 homolog Microspherule protein 1 Mortality factor 4-like protein 1 Mortality factor 4-like protein 2 Nuclear receptor coactivator 1 Nuclear receptor coactivator 2 PHD finger protein 20 Paired box protein Pax-3 Peregrin Protein Dr1 Protein Jade-1 Protein Jade-3 RuvB-like 1 RuvB-like 2 SAGA-associated factor 29 STAGA complex 65 subunit gamma TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L Transcription and mRNA export factor ENY2 Transcription factor SPT20 homolog Transcription initiation factor TFIID subunit 10 Transcription initiation factor TFIID subunit 12 Transcription initiation factor TFIID subunit 9 Transcription initiation protein SPT3 homolog Transcriptional adapter 1 Transcriptional adapter 2-alpha Transcriptional adapter 2-beta Transcriptional adapter 3 Transformation/transcription domain-associated protein UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit Ubiquitin carboxyl-terminal hydrolase 22 Vacuolar protein sorting-associated protein 72 homolog WD repeat-containing protein 5 YEATS domain-containing protein 2 YEATS domain-containing protein 4 ZZ-type zinc finger-containing protein 3	O14929 O15265 O15294 O15516 O60814 O75478 O75486 O75528 O75529 O94864 O95163 O95251 O95619 O95696 O96019 P04908 P06899 P0C0S8 P15336 P20671 P23527 P23760 P33778 P51610 P55201 P58876 P60709 P61964 P62805 P62807 P68431 Q01658 Q09472 Q0PNE2 Q12962 Q14CW9 Q15014 Q15596 Q15788 Q15906 Q16514 Q16576 Q16594 Q16777 Q16778 Q5QNW6 Q68DK7 Q6FI13 Q6IA86 Q6IE81 Q71DI3 Q7L7L0 Q7Z3B3 Q86TJ2 Q8IUE6 Q8IYH5 Q8N257 Q8N5Y2 Q8NEM7 Q8TE02 Q8WYB5 Q8WYH8 Q92613 Q92793 Q92794 Q92830 Q92831 Q92993 Q93077 Q93079 Q96A08 Q96BN2 Q96EB1 Q96ES7 Q96EZ8 Q96KK5 Q96L91 Q96QV6 Q99877 Q99878 Q99879 Q99880 Q9BVI0 Q9H0E3 Q9H0E9 Q9H2F5 Q9H7Z6 Q9H8E8 Q9H9L4 Q9H9T3 Q9HAF1 Q9HCI7 Q9NPA8 Q9NPF5 Q9NQC1 Q9NS73 Q9NV56 Q9NXR8 Q9P2N6 Q9UBU8 Q9ULD4 Q9ULM3 Q9UNL4 Q9UPT9 Q9Y230 Q9Y265 Q9Y4A5 Q9Y6J9	ACTB ACTL6A ADA2B ADA3 ATF2 ATP1 ATXN7 ATXN7L3 BAF53 BAF53A BHLHE74 BHLHE75 BHLHE8 BIG3 BR140 BRD1 BRD8 BRL BRPF1 BRPF2 BRPF3 C11orf19 C12orf41 C13orf19 C17orf81 C1orf149 C20orf104 C20orf20 C3orf75 CAGH32 CBP CCDC101 CENP-28 CENP-36 CLOCK CREB2 CREBBP CREBP1 CSRP2BP DERP6 DMAP1 DR1 EAF6 ELP1 ELP2 ELP3 ELP4 ELP5 ELP6 ENY2 EP300 EP400 EPC1 FAM48A GAS41 GCN5 GCN5L2 GLEA2 H2AC1 H2AC11 H2AC12 H2AC13 H2AC14 H2AC15 H2AC16 H2AC17 H2AC18 H2AC19 H2AC20 H2AC21 H2AC25 H2AC4 H2AC6 H2AC7 H2AC8 H2AFA H2AFC H2AFD H2AFE H2AFG H2AFI H2AFL H2AFM H2AFN H2AFO H2AFP H2AFQ H2AFR H2AW H2BC1 H2BC10 H2BC11 H2BC12 H2BC13 H2BC14 H2BC15 H2BC17 H2BC18 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H2BFA H2BFB H2BFC H2BFD H2BFE H2BFF H2BFG H2BFH H2BFJ H2BFK H2BFL H2BFN H2BFQ H2BFR H2BFT H2BU1 H3C1 H3C10 H3C11 H3C12 H3C13 H3C14 H3C15 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 H3F2 H3FA H3FB H3FC HIST1H3C H3FD H3FF H3FH H3FI H3FJ H3FK H3FL H3FM H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HAT1 HBO1 HBOa HCA58 HCF1 HCFC1 HFC1 HIRIP1 HIRIP2 HIST1H2AA HIST1H2AB HIST1H2AC HIST1H2AD HIST1H2AE HIST1H2AG HIST1H2AH HIST1H2AI HIST1H2AJ HIST1H2AK HIST1H2AL HIST1H2AM HIST1H2BA HIST1H2BB HIST1H2BC HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2BI HIST1H2BJ HIST1H2BK HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST1H3A HIST1H3B HIST1H3D HIST1H3E HIST1H3F HIST1H3G HIST1H3H HIST1H3I HIST1H3J HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H2AA HIST2H2AA3 HIST2H2AA4 HIST2H2AB HIST2H2AC HIST2H2BE HIST2H2BF HIST2H3A HIST2H3C HIST2H3D HIST2H4 HIST2H4A HIST2H4B HIST3H2A HIST3H2BB HIST4H4 HTATIP HUP2 IKAP IKBKAP ING3 ING4 ING5 INO80H INO80J INO80K INO80Q JADE1 JADE2 JADE3 KANSL1 KANSL2 KANSL3 KAT1 KAT14 KAT2A KAT2B KAT5 KAT6A KAT6B KAT7 KAT8 KIAA0026 KIAA0215 KIAA0239 KIAA0334 KIAA0383 KIAA0764 KIAA1063 KIAA1197 KIAA1267 KIAA1286 KIAA1310 KIAA1425 KIAA1498 KIAA1585 KIAA1807 KIAA1818 MBIP MCRS1 MEAF6 MOF MORF MORF4L1 MORF4L2 MOZ MOZ2 MRG15 MRGBP MRGX MSL1 MSL1L1 MSL1V1 MSL2 MSL2L1 MSL3 MSL3L1 MSP58 MYST1 MYST2 MYST3 MYST4 NCOA1 NCOA2 NMP238 NSL1 NSL2 NSL3 NZF OGT P300 PAF400 PAF65A PAF65B PAX3 PAXNEB PCAF PHF15 PHF16 PHF17 PHF20 PRTD RBAP46 RBBP7 RNF184 RUNXBP2 RUVBL1 RUVBL2 SAP130 SCA7 SGF29 SI1 SMAP SMAP2 SPT3 SRC1 SRC2 STATIP1 SUPT20H SUPT3H SUPT7L TADA1 TADA1L TADA2A TADA2B TADA2L TADA3 TADA3L TAF10 TAF12 TAF15 TAF2A TAF2G TAF2H TAF2J TAF5L TAF6L TAF9 TAFII20 TAFII30 TAFII31 TCFL1 TIF2 TIP48 TIP49 TIP49A TIP49B TIP60 TMEM103 TNRC12 TRRAP TSH2B TZP USP22 USP3L VPS72 WDR5 YEATS2 YEATS4 YL1 ZNF220 ZZZ3	Homo sapiens (human)
Mitochondrial protein import	4-hydroxybenzoate polyprenyltransferase, mitochondrial 60 kDa heat shock protein, mitochondrial ADP/ATP translocase 1 ADP/ATP translocase 3 ATP synthase F(0) complex subunit C1, mitochondrial ATP synthase subunit alpha, mitochondrial ATP synthase subunit beta, mitochondrial Aconitate hydratase, mitochondrial COX assembly mitochondrial protein 2 homolog Citrate synthase, mitochondrial Coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial Coiled-coil-helix-coiled-coil-helix domain-containing protein 2 Coiled-coil-helix-coiled-coil-helix domain-containing protein 5 Coiled-coil-helix-coiled-coil-helix domain-containing protein 7 Cx9C motif-containing protein 4 Cytochrome c oxidase assembly factor 4 homolog, mitochondrial Cytochrome c oxidase assembly factor 6 homolog Cytochrome c oxidase assembly protein COX19 Cytochrome c oxidase copper chaperone Cytochrome c1, heme protein, mitochondrial Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial FAD-linked sulfhydryl oxidase ALR Frataxin, mitochondrial GrpE protein homolog 1, mitochondrial GrpE protein homolog 2, mitochondrial Iron-sulfur cluster co-chaperone protein HscB Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial MICOS complex subunit MIC19 Metaxin-1 Metaxin-2 Mitochondrial chaperone BCS1 Mitochondrial import inner membrane translocase subunit TIM14 Mitochondrial import inner membrane translocase subunit TIM16 Mitochondrial import inner membrane translocase subunit TIM44 Mitochondrial import inner membrane translocase subunit TIM50 Mitochondrial import inner membrane translocase subunit Tim10 B Mitochondrial import inner membrane translocase subunit Tim10 Mitochondrial import inner membrane translocase subunit Tim13 Mitochondrial import inner membrane translocase subunit Tim17-A Mitochondrial import inner membrane translocase subunit Tim17-B Mitochondrial import inner membrane translocase subunit Tim21 Mitochondrial import inner membrane translocase subunit Tim22 Mitochondrial import inner membrane translocase subunit Tim23 Mitochondrial import inner membrane translocase subunit Tim8 A Mitochondrial import inner membrane translocase subunit Tim8 B Mitochondrial import inner membrane translocase subunit Tim9 Mitochondrial import receptor subunit TOM20 homolog Mitochondrial import receptor subunit TOM22 homolog Mitochondrial import receptor subunit TOM40 homolog Mitochondrial import receptor subunit TOM5 homolog Mitochondrial import receptor subunit TOM6 homolog Mitochondrial import receptor subunit TOM7 homolog Mitochondrial import receptor subunit TOM70 Mitochondrial intermembrane space import and assembly protein 40 Mitochondrial-processing peptidase subunit alpha Mitochondrial-processing peptidase subunit beta NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial Ornithine transcarbamylase, mitochondrial Presequence protease, mitochondrial Probable D-lactate dehydrogenase, mitochondrial Sorting and assembly machinery component 50 homolog Stress-70 protein, mitochondrial Tafazzin Voltage-dependent anion-selective channel protein 1	O14925 O43615 O60220 O60830 O75390 O75431 O75439 O75746 O94826 O95169 O96008 P00480 P05496 P06576 P08574 P10809 P12235 P12236 P21796 P25705 P38646 P51553 P55789 P56277 P62072 Q10713 Q13505 Q14061 Q15388 Q16595 Q16635 Q3ZCQ8 Q49B96 Q5JRX3 Q5JTJ3 Q86WU2 Q8IWL3 Q8N4H5 Q8N4Q1 Q8TAA5 Q8WYQ3 Q96B49 Q96DA6 Q96H96 Q99595 Q99798 Q9BSY4 Q9BUK0 Q9BVV7 Q9HAV7 Q9NRP2 Q9NS69 Q9NX63 Q9NYJ1 Q9P0U1 Q9UJS0 Q9Y276 Q9Y3D7 Q9Y512 Q9Y584 Q9Y5J6 Q9Y5J7 Q9Y5J9 Q9Y5L4 Q9Y6H1	AAC1 AAC3 ACO2 AGC1 ALR ANT1 ANT3 ARALAR1 ATP5A ATP5A1 ATP5AL2 ATP5B ATP5F1A ATP5F1B ATP5G1 ATP5MC1 ATPM ATPMB ATPSB BCS1 BCS1L C16orf61 C18orf55 C19orf1 C1orf31 C22orf16 C2orf9 C6.1B C7orf17 C9orf105 CHCHD10 CHCHD2 CHCHD3 CHCHD4 CHCHD5 CHCHD7 CHCHD8 CL640 CMC2 CMC4 COA4 COA6 COQ2 COX17 COX19 CS CYC1 DDP DDP1 DDP2 DDPL DNAJC19 DNAJC20 E2IG2 EFE2 FRDA FXC1 FXN G4.5 GFER GREPEL1 GRP75 GRPEL1 GRPEL2 HERV1 HPO HSC20 HSCB HSP60 HSPA9 HSPA9B HSPD1 IDH3G INPP5E KIAA0016 KIAA0123 KIAA0719 KIAA1104 LDHD MAGMAS MIA40 MIC19 MIMT17 MIMT44 MINOS3 MP1 MPPA MPPB MTCP1 MTCP1NB MTX MTX1 MTX2 MTXN NDUFB8 OBTP OTC PAM16 PEREC1 PITRM1 PMPCA PMPCB PREP SAM50 SAMM50 SLC25A12 SLC25A13 SLC25A4 SLC25A6 TAFAZZIN TAZ TEX4 TIM10 TIM13B TIM14 TIM16 TIM17 TIM17A TIM17B TIM21 TIM22 TIM23 TIM44 TIM50 TIM8A TIM8B TIM9 TIM9A TIM9B TIMM10 TIMM10B TIMM13 TIMM13A TIMM13B TIMM14 TIMM16 TIMM17 TIMM17A TIMM17B TIMM21 TIMM22 TIMM23 TIMM44 TIMM50 TIMM8A TIMM8B TIMM9 TIMM9A TIMM9B TOM22 TOM40 TOM5 TOM6 TOM7 TOM70 TOMM07 TOMM20 TOMM22 TOMM40 TOMM5 TOMM6 TOMM7 TOMM70 TOMM70A VDAC VDAC1 X25 mt-HSP70	Homo sapiens (human)
NF-kB is activated and signals survival	Beta-nerve growth factor Inhibitor of nuclear factor kappa-B kinase subunit beta Interleukin-1 receptor-associated kinase 1 NF-kappa-B inhibitor alpha Nuclear factor NF-kappa-B p105 subunit Polyubiquitin-B Polyubiquitin-C Sequestosome-1 TNF receptor-associated factor 6 Transcription factor p65 Tumor necrosis factor receptor superfamily member 16 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O14920 P01138 P08138 P0CG47 P0CG48 P19838 P25963 P51617 P62979 P62987 Q04206 Q13501 Q9Y4K3	IKBA IKBKB IKKB IRAK IRAK1 MAD3 NFKB1 NFKB3 NFKBI NFKBIA NGF NGFB NGFR ORCA OSIL RELA RNF85 RPS27A SQSTM1 TNFRSF16 TRAF6 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Homo sapiens (human)
p75NTR recruits signalling complexes	Beta-nerve growth factor Inhibitor of nuclear factor kappa-B kinase subunit beta Interleukin-1 receptor-associated kinase 1 Myeloid differentiation primary response protein MyD88 Polyubiquitin-B Polyubiquitin-C Protein kinase C iota type Receptor-interacting serine/threonine-protein kinase 2 Sequestosome-1 TNF receptor-associated factor 6 Tumor necrosis factor receptor superfamily member 16 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O14920 O43353 P01138 P08138 P0CG47 P0CG48 P41743 P51617 P62979 P62987 Q13501 Q99836 Q9Y4K3	CARDIAK DXS1179E IKBKB IKKB IRAK IRAK1 MYD88 NGF NGFB NGFR ORCA OSIL PRKCI RICK RIP2 RIPK2 RNF85 RPS27A SQSTM1 TNFRSF16 TRAF6 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Homo sapiens (human)
IKBKB deficiency causes SCID	Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta NF-kappa-B essential modulator	O14920 O15111 Q9Y6K9	CHUK FIP3 IKBKB IKBKG IKKA IKKB NEMO TCF16	Homo sapiens (human)
IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR)	Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta NF-kappa-B essential modulator	O14920 O15111 Q9Y6K9	CHUK FIP3 IKBKB IKBKG IKKA IKKB NEMO TCF16	Homo sapiens (human)
IRAK1 recruits IKK complex	E3 ubiquitin-protein ligase pellino homolog 1 E3 ubiquitin-protein ligase pellino homolog 2 E3 ubiquitin-protein ligase pellino homolog 3 Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Interleukin-1 receptor-associated kinase 1 NF-kappa-B essential modulator TNF receptor-associated factor 6 Ubiquitin-conjugating enzyme E2 N Ubiquitin-conjugating enzyme E2 variant 1	O14920 O15111 P51617 P61088 Q13404 Q8N2H9 Q96FA3 Q9HAT8 Q9Y4K3 Q9Y6K9	BLU CHUK CROC1 FIP3 IKBKB IKBKG IKKA IKKB IRAK IRAK1 NEMO PELI1 PELI2 PELI3 PRISM RNF85 TCF16 TRAF6 UBE2N UBE2V UBE2V1 UEV1	Homo sapiens (human)
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation	E3 ubiquitin-protein ligase pellino homolog 1 E3 ubiquitin-protein ligase pellino homolog 2 E3 ubiquitin-protein ligase pellino homolog 3 Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Interleukin-1 receptor-associated kinase 1 NF-kappa-B essential modulator TNF receptor-associated factor 6 Ubiquitin-conjugating enzyme E2 N Ubiquitin-conjugating enzyme E2 variant 1	O14920 O15111 P51617 P61088 Q13404 Q8N2H9 Q96FA3 Q9HAT8 Q9Y4K3 Q9Y6K9	BLU CHUK CROC1 FIP3 IKBKB IKBKG IKKA IKKB IRAK IRAK1 NEMO PELI1 PELI2 PELI3 PRISM RNF85 TCF16 TRAF6 UBE2N UBE2V UBE2V1 UEV1	Homo sapiens (human)
IkBA variant leads to EDA-ID	Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta NF-kappa-B essential modulator NF-kappa-B inhibitor alpha Nuclear factor NF-kappa-B p100 subunit Nuclear factor NF-kappa-B p105 subunit Transcription factor p65	O14920 O15111 P19838 P25963 Q00653 Q04206 Q9Y6K9	CHUK FIP3 IKBA IKBKB IKBKG IKKA IKKB LYT10 MAD3 NEMO NFKB1 NFKB2 NFKB3 NFKBI NFKBIA RELA TCF16	Homo sapiens (human)
MAP3K8 (TPL2)-dependent MAPK1/3 activation	Cullin-1 Dual specificity mitogen-activated protein kinase kinase 1 Dual specificity mitogen-activated protein kinase kinase 4 F-box/WD repeat-containing protein 11 F-box/WD repeat-containing protein 1A Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Mitogen-activated protein kinase kinase kinase 8 NF-kappa-B essential modulator Nuclear factor NF-kappa-B p105 subunit Polyubiquitin-B Polyubiquitin-C S-phase kinase-associated protein 1 TNFAIP3-interacting protein 2 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O14920 O15111 P0CG47 P0CG48 P19838 P41279 P45985 P62979 P62987 P63208 Q02750 Q13616 Q8NFZ5 Q9UKB1 Q9Y297 Q9Y6K9	ABIN2 BTRC BTRCP BTRCP2 CHUK COT CUL1 EMC19 ESTF FBW1A FBW1B FBXW11 FBXW1A FBXW1B FIP3 FLIP1 IKBKB IKBKG IKKA IKKB JNKK1 KIAA0696 MAP2K1 MAP2K4 MAP3K8 MEK1 MEK4 MKK4 NEMO NFKB1 OCP2 PRKMK1 PRKMK4 RPS27A SEK1 SERK1 SKK1 SKP1 SKP1A TCEB1L TCF16 TNIP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Homo sapiens (human)

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