GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **1876 - 1900** of **2090** in total

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Pathway Name ▲	Protein Name	UniProt ID	Gene Symbol	Organism
TYSND1 cleaves peroxisomal proteins	3-ketoacyl-CoA thiolase, peroxisomal Alkyldihydroxyacetonephosphate synthase, peroxisomal Peroxisomal acyl-coenzyme A oxidase 1 Peroxisomal leader peptide-processing protease Peroxisomal multifunctional enzyme type 2 Phytanoyl-CoA dioxygenase, peroxisomal Sterol carrier protein 2	O00116 O14832 P09110 P22307 P51659 Q15067 Q2T9J0	ACAA ACAA1 ACOX ACOX1 AGPS EDH17B4 HSD17B4 PAHX PHYH PTHIO SCP2 SDR8C1 TYSND1	Homo sapiens (human)
Tachykinin receptors bind tachykinins	Neuromedin-K receptor Protachykinin-1 Substance-K receptor Substance-P receptor Tachykinin-3	P20366 P21452 P25103 P29371 Q9UHF0	NK1R NK2R NK3R NKA NKNA NKNAR NKNB TAC1 TAC1R TAC2 TAC2R TAC3 TAC3R TACR1 TACR2 TACR3	Homo sapiens (human)
Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)	Potassium channel subfamily K member 1 Potassium channel subfamily K member 6 Potassium channel subfamily K member 7	O00180 Q9Y257 Q9Y2U2	HOHO1 KCNK1 KCNK6 KCNK7 KCNO1 TOSS TWIK1 TWIK2	Homo sapiens (human)
Tandem pore domain halothane-inhibited K+ channel (THIK)	Potassium channel subfamily K member 13	Q9HB14	KCNK13	Homo sapiens (human)
Tat-mediated HIV elongation arrest and recovery	Cyclin-T1 Cyclin-dependent kinase 9 DNA-directed RNA polymerase II subunit RPB11-a DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 Elongin-A2 Elongin-A Elongin-B Elongin-C FACT complex subunit SPT16 FACT complex subunit SSRP1 General transcription factor IIF subunit 1 General transcription factor IIF subunit 2 Negative elongation factor A Negative elongation factor B Negative elongation factor C/D Negative elongation factor E Protein Tat RNA polymerase II elongation factor ELL RNA polymerase II subunit A C-terminal domain phosphatase Transcription elongation factor A protein 1 Transcription elongation factor SPT4 Transcription elongation factor SPT5	O00267 O15514 O60563 P04608 P13984 P18615 P19387 P19388 P23193 P24928 P30876 P35269 P36954 P50750 P52434 P52435 P53803 P55199 P61218 P62487 P62875 P63272 Q08945 Q14241 Q15369 Q15370 Q8IXH7 Q8IYF1 Q8WX92 Q9H3P2 Q9Y5B0 Q9Y5B9	C19orf17 CCNT1 CDC2L4 CDK9 COBRA1 CTDP1 ELL ELOA ELOA2 ELOB ELOC FACT140 FACT80 FACTP140 FCP1 GTF2F1 GTF2F2 GTF2S KIAA1182 NELFA NELFB NELFCD NELFD NELFE POLR2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J1 POLR2K POLR2L POLRF RAP30 RAP74 RD RDBP RPB7 SPT4H SPT5 SPT5H SSRP1 SUPT16H SUPT4H SUPT4H1 SUPT5H TAK TCEA1 TCEB1 TCEB2 TCEB3 TCEB3B TCEB3L TFIIS TH1 TH1L WHSC2 tat	Homo sapiens (human)
Tat-mediated elongation of the HIV-1 transcript	CDK-activating kinase assembly factor MAT1 Cyclin-H Cyclin-T1 Cyclin-dependent kinase 7 Cyclin-dependent kinase 9 DNA-directed RNA polymerase II subunit RPB11-a DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 Elongin-A2 Elongin-A Elongin-B Elongin-C FACT complex subunit SPT16 FACT complex subunit SSRP1 General transcription and DNA repair factor IIH helicase subunit XPD General transcription and DNA repair factor IIH helicase/translocase subunit XPB General transcription factor IIF subunit 1 General transcription factor IIF subunit 2 General transcription factor IIH subunit 1 General transcription factor IIH subunit 2 General transcription factor IIH subunit 3 General transcription factor IIH subunit 4 General transcription factor IIH subunit 5 Negative elongation factor A Negative elongation factor B Negative elongation factor C/D Negative elongation factor E Protein Tat RNA polymerase II elongation factor ELL RNA polymerase II subunit A C-terminal domain phosphatase Transcription elongation factor A protein 1 Transcription elongation factor SPT4 Transcription elongation factor SPT5	O00267 O15514 O60563 P04608 P13984 P18074 P18615 P19387 P19388 P19447 P23193 P24928 P30876 P32780 P35269 P36954 P50613 P50750 P51946 P51948 P52434 P52435 P53803 P55199 P61218 P62487 P62875 P63272 Q08945 Q13888 Q13889 Q14241 Q15369 Q15370 Q6ZYL4 Q8IXH7 Q8IYF1 Q8WX92 Q92759 Q9H3P2 Q9Y5B0 Q9Y5B9	BTF2 BTF2P44 C19orf17 C6orf175 CAK CAK1 CAP35 CCNH CCNT1 CDC2L4 CDK7 CDK9 CDKN7 COBRA1 CTDP1 ELL ELOA ELOA2 ELOB ELOC ERCC2 ERCC3 FACT140 FACT80 FACTP140 FCP1 GTF2F1 GTF2F2 GTF2H1 GTF2H2 GTF2H3 GTF2H4 GTF2H5 GTF2S KIAA1182 MAT1 MNAT1 MO15 NELFA NELFB NELFCD NELFD NELFE POLR2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J1 POLR2K POLR2L POLRF RAP30 RAP74 RD RDBP RNF66 RPB7 SPT4H SPT5 SPT5H SSRP1 STK1 SUPT16H SUPT4H SUPT4H1 SUPT5H TAK TCEA1 TCEB1 TCEB2 TCEB3 TCEB3B TCEB3L TFIIS TH1 TH1L TTDA WHSC2 XPB XPBC XPD XPDC tat	Homo sapiens (human)
Telomere C-strand (Lagging Strand) Synthesis	Adrenocortical dysplasia protein homolog DNA polymerase delta catalytic subunit DNA polymerase delta subunit 2 DNA polymerase delta subunit 3 DNA polymerase delta subunit 4 Proliferating cell nuclear antigen Protection of telomeres protein 1 TERF1-interacting nuclear factor 2 Telomeric repeat-binding factor 1 Telomeric repeat-binding factor 2-interacting protein 1 Telomeric repeat-binding factor 2	P12004 P28340 P49005 P54274 Q15054 Q15554 Q96AP0 Q9BSI4 Q9HCU8 Q9NUX5 Q9NYB0	ACD DRIP5 KIAA0039 PCNA PIN2 PIP1 POLD POLD1 POLD2 POLD3 POLD4 POLDS POT1 PTOP RAP1 TERF1 TERF2 TERF2IP TIN2 TINF2 TINT1 TPP1 TRBF1 TRBF2 TRF TRF1 TRF2	Homo sapiens (human)
Telomere C-strand synthesis initiation	Adrenocortical dysplasia protein homolog CST complex subunit CTC1 CST complex subunit STN1 CST complex subunit TEN1 DNA polymerase alpha catalytic subunit DNA polymerase alpha subunit B DNA primase large subunit DNA primase small subunit Protection of telomeres protein 1 TERF1-interacting nuclear factor 2 Telomeric repeat-binding factor 1 Telomeric repeat-binding factor 2-interacting protein 1 Telomeric repeat-binding factor 2	P09884 P49642 P49643 P54274 Q14181 Q15554 Q2NKJ3 Q86WV5 Q96AP0 Q9BSI4 Q9H668 Q9NUX5 Q9NYB0	ACD C17orf106 C17orf68 CTC1 DRIP5 OBFC1 PIN2 PIP1 POLA POLA1 POLA2 POT1 PRIM1 PRIM2 PRIM2A PTOP RAP1 STN1 TEN1 TERF1 TERF2 TERF2IP TIN2 TINF2 TINT1 TPP1 TRBF1 TRBF2 TRF TRF1 TRF2	Homo sapiens (human)
Telomere Extension By Telomerase	ATP-dependent DNA helicase PIF1 Adrenocortical dysplasia protein homolog Cyclin-A1 Cyclin-A2 Cyclin-dependent kinase 2 H/ACA ribonucleoprotein complex subunit 1 H/ACA ribonucleoprotein complex subunit 2 H/ACA ribonucleoprotein complex subunit 3 H/ACA ribonucleoprotein complex subunit DKC1 Protection of telomeres protein 1 Protein SHQ1 homolog Regulator of telomere elongation helicase 1 RuvB-like 1 RuvB-like 2 Serine/threonine-protein phosphatase 6 catalytic subunit Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A Serine/threonine-protein phosphatase 6 regulatory subunit 3 TERF1-interacting nuclear factor 2 Telomerase Cajal body protein 1 Telomerase reverse transcriptase Telomeric repeat-binding factor 1 Telomeric repeat-binding factor 2-interacting protein 1 Telomeric repeat-binding factor 2	O00743 O14746 O15084 O60832 P20248 P24941 P54274 P78396 Q15554 Q5H9R7 Q6PI26 Q96AP0 Q9BSI4 Q9BUR4 Q9H611 Q9NPE3 Q9NUX5 Q9NX24 Q9NY12 Q9NYB0 Q9NZ71 Q9Y230 Q9Y265	ACD ANKRD28 C11orf23 C15orf20 C20orf41 CCN1 CCNA CCNA1 CCNA2 CDK2 CDKN2 DKC1 DRIP5 EST2 GAR1 INO80H INO80J KIAA0379 KIAA1088 KIAA1558 NHL NHP2 NMP238 NOLA1 NOLA2 NOLA3 NOLA4 NOP10 PIF1 PIN2 PIP1 POT1 PP6R3 PPP6 PPP6C PPP6R3 PTOP RAP1 RTEL1 RUVBL1 RUVBL2 SAPL SAPS3 SHQ1 TCAB1 TCS1 TERF1 TERF2 TERF2IP TERT TIN2 TINF2 TINT1 TIP48 TIP49 TIP49A TIP49B TPP1 TRBF1 TRBF2 TRF TRF1 TRF2 TRT WDR79 WRAP53	Homo sapiens (human)
Terminal pathway of complement	Clusterin Complement C5 Complement component C6 Complement component C7 Complement component C8 alpha chain Complement component C8 beta chain Complement component C8 gamma chain Complement component C9	P01031 P02748 P07357 P07358 P07360 P10643 P10909 P13671	APOJ C5 C6 C7 C8A C8B C8G C9 CLI CLU CPAMD4 KUB1	Homo sapiens (human)
Termination of O-glycan biosynthesis	Alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide alpha-2,6-sialyltransferase Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 Beta-galactoside alpha-2,6-sialyltransferase 1 CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 Mucin-12 Mucin-13 Mucin-15 Mucin-16 Mucin-17 Mucin-19 Mucin-1 Mucin-20 Mucin-21 Mucin-2 Mucin-3A Mucin-3B Mucin-4 Mucin-5AC Mucin-5B Mucin-6 Mucin-7 Mucin-like protein 1	P15907 P15941 P98088 Q02505 Q02817 Q11201 Q11203 Q11206 Q16842 Q5SSG8 Q685J3 Q6W4X9 Q7Z5P9 Q8N307 Q8N387 Q8NDV1 Q8TAX7 Q8WXI7 Q96DR8 Q99102 Q9H195 Q9H3R2 Q9H4F1 Q9HC84 Q9UJ37 Q9UKN1	C6orf205 CA125 CGS23 DRCC1 KIAA1359 MG2 MUC1 MUC11 MUC12 MUC13 MUC15 MUC16 MUC17 MUC19 MUC2 MUC20 MUC21 MUC3 MUC3A MUC3B MUC4 MUC5 MUC5AC MUC5B MUC6 MUC7 MUCL1 NANTA3 PUM RECC SBEM SIAT1 SIAT3C SIAT4 SIAT4A SIAT4B SIAT4C SIAT6 SIAT7B SIAT7C SIAT7D SIATL1 SMUC ST3GAL1 ST3GAL2 ST3GAL3 ST3GAL4 ST6GAL1 ST6GALNAC2 ST6GALNAC3 ST6GALNAC4 STHM STZ	Homo sapiens (human)
Termination of translesion DNA synthesis	DNA polymerase delta catalytic subunit DNA polymerase delta subunit 2 DNA polymerase delta subunit 3 DNA polymerase delta subunit 4 DNA polymerase epsilon catalytic subunit A DNA polymerase epsilon subunit 2 DNA polymerase epsilon subunit 3 DNA polymerase epsilon subunit 4 DNA polymerase eta DNA polymerase iota DNA polymerase kappa DNA repair protein REV1 E3 ubiquitin/ISG15 ligase TRIM25 PCNA-associated factor Polyubiquitin-B Polyubiquitin-C Proliferating cell nuclear antigen Replication factor C subunit 1 Replication factor C subunit 2 Replication factor C subunit 3 Replication factor C subunit 4 Replication factor C subunit 5 Replication protein A 14 kDa subunit Replication protein A 32 kDa subunit Replication protein A 70 kDa DNA-binding subunit Ubiquitin carboxyl-terminal hydrolase 10 Ubiquitin carboxyl-terminal hydrolase 43 Ubiquitin-like modifier-activating enzyme 7 Ubiquitin-like protein ISG15 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Ubiquitin/ISG15-conjugating enzyme E2 L6	O14933 P05161 P0CG47 P0CG48 P12004 P15927 P27694 P28340 P35244 P35249 P35250 P35251 P40937 P40938 P41226 P49005 P56282 P62979 P62987 Q07864 Q14258 Q14694 Q15004 Q15054 Q70EL4 Q9HCU8 Q9NR33 Q9NRF9 Q9UBT6 Q9UBZ9 Q9UNA4 Q9Y253	CHRAC17 DINB1 DPE2 EFP G1P2 ISG15 KIAA0039 KIAA0101 KIAA0190 NS5ATP9 PAF PCLAF PCNA POLD POLD1 POLD2 POLD3 POLD4 POLDS POLE POLE1 POLE2 POLE3 POLE4 POLH POLI POLK RAD30 RAD30A RAD30B REPA1 REPA2 REPA3 REV1 REV1L RFC1 RFC140 RFC2 RFC3 RFC4 RFC5 RNF147 RPA1 RPA14 RPA2 RPA3 RPA32 RPA34 RPA70 RPS27A TRIM25 UBA52 UBA7 UBA80 UBB UBC UBCEP1 UBCEP2 UBCH8 UBE1L UBE2 UBE2L6 UCRP USP10 USP43 XPV ZNF147	Homo sapiens (human)
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation	6-pyruvoyl tetrahydrobiopterin synthase Calmodulin-1 Dihydrofolate reductase GTP cyclohydrolase 1 feedback regulatory protein GTP cyclohydrolase 1 Heat shock protein HSP 90-alpha Nitric oxide synthase 3 RAC-alpha serine/threonine-protein kinase Sepiapterin reductase cGMP-dependent protein kinase 2	P00374 P07900 P0DP23 P29474 P30047 P30793 P31749 P35270 Q03393 Q13237	AKT1 CALM CALM1 CAM CAM1 DHFR DYT5 GCH GCH1 GCHFR GFRP HSP90A HSP90AA1 HSPC1 HSPCA NOS3 PKB PRKG2 PRKGR2 PTS RAC SPR	Homo sapiens (human)
The NLRP3 inflammasome	Alpha-hemolysin Amyloid-beta precursor protein Apoptosis-associated speck-like protein containing a CARD Caspase-1 Heat shock protein HSP 90-beta Heme oxygenase 1 NACHT, LRR and PYD domains-containing protein 3 Nuclear factor NF-kappa-B p100 subunit Nuclear factor NF-kappa-B p105 subunit P2X purinoceptor 7 Pannexin-1 Proline-serine-threonine phosphatase-interacting protein 1 Protein SGT1 homolog Pyrin Thioredoxin-interacting protein Thioredoxin Transcription factor p65	O15553 O43586 P05067 P08238 P09601 P09616 P10599 P19838 P29466 Q00653 Q04206 Q96P20 Q96RD7 Q99572 Q9H3M7 Q9ULZ3 Q9Y2Z0	A4 AD1 APP ASC C1orf7 CARD5 CASP1 CD2BP1 CIAS1 HMOX1 HO HO1 HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB IL1BC IL1BCE LYT10 MEF MEFV MRS1 NALP3 NFKB1 NFKB2 NFKB3 NLRP3 P2RX7 PANX1 PSTPIP1 PYCARD PYPAF1 RELA SUGT1 TMS1 TRDX TRIM20 TRX TRX1 TXN TXNIP VDUP1 hla hly	Homo sapiens (human)
The activation of arylsulfatases	Arylsulfatase A Arylsulfatase B Arylsulfatase D Arylsulfatase F Arylsulfatase G Arylsulfatase H Arylsulfatase I Arylsulfatase J Arylsulfatase K Arylsulfatase L Formylglycine-generating enzyme Inactive C-alpha-formylglycine-generating enzyme 2 Steryl-sulfatase	P08842 P15289 P15848 P51689 P51690 P54793 Q5FYA8 Q5FYB0 Q5FYB1 Q6UWY0 Q8NBJ7 Q8NBK3 Q96EG1	ARSA ARSB ARSC1 ARSD ARSE ARSF ARSG ARSH ARSI ARSJ ARSK ARSL KIAA1001 STS SUMF1 SUMF2 TSULF	Homo sapiens (human)
The canonical retinoid cycle in rods (twilight vision)	17-beta-hydroxysteroid dehydrogenase type 1 17-beta-hydroxysteroid dehydrogenase type 6 Cytochrome P450 4V2 Dehydrogenase/reductase SDR family member 9 Lecithin retinol acyltransferase Receptor for retinol uptake STRA6 Retinal-specific phospholipid-transporting ATPase ABCA4 Retinaldehyde-binding protein 1 Retinoid isomerohydrolase Retinol dehydrogenase 10 Retinol dehydrogenase 11 Retinol dehydrogenase 12 Retinol dehydrogenase 16 Retinol dehydrogenase 5 Retinol dehydrogenase 8 Retinol-binding protein 1 Retinol-binding protein 3 Retinol-binding protein 4 Rhodopsin Short-chain dehydrogenase/reductase family 9C member 7 Transthyretin Unconventional myosin-VIIa	O14756 O75452 O95237 P02753 P02766 P08100 P09455 P10745 P12271 P14061 P78363 Q13402 Q16518 Q6ZWL3 Q8IZV5 Q8NEX9 Q8TC12 Q92781 Q96NR8 Q9BPW9 Q9BX79 Q9NYR8	ABCA4 ABCR ARSDR1 CRALBP CRBP1 CYP4V2 DHRS9 E17KSR EDH17B1 EDH17B2 EDHB17 HSD17B1 HSD17B6 HSD17B9 LRAT MYO7A OPN2 PALB PRRDH PSDR1 RBP1 RBP3 RBP4 RDH1 RDH10 RDH11 RDH12 RDH15 RDH16 RDH5 RDH8 RDHS RHO RLBP1 RODH RODH4 RPE65 SDR16C4 SDR28C1 SDR28C2 SDR7C1 SDR7C2 SDR9C4 SDR9C5 SDR9C6 SDR9C7 SDR9C8 SDRO STRA6 TTR USH1B	Homo sapiens (human)
The fatty acid cycling model	Brain mitochondrial carrier protein 1 Dicarboxylate carrier SLC25A8 Mitochondrial brown fat uncoupling protein 1 Mitochondrial uncoupling protein 4 Putative mitochondrial transporter UCP3	O95258 O95847 P25874 P55851 P55916	BMCP1 SLC25A14 SLC25A27 SLC25A7 SLC25A8 SLC25A9 UCP UCP1 UCP2 UCP3 UCP4 UCP5	Homo sapiens (human)
The proton buffering model	Brain mitochondrial carrier protein 1 Dicarboxylate carrier SLC25A8 Mitochondrial brown fat uncoupling protein 1 Mitochondrial uncoupling protein 4 Putative mitochondrial transporter UCP3	O95258 O95847 P25874 P55851 P55916	BMCP1 SLC25A14 SLC25A27 SLC25A7 SLC25A8 SLC25A9 UCP UCP1 UCP2 UCP3 UCP4 UCP5	Homo sapiens (human)
The retinoid cycle in cones (daylight vision)	Acyl-CoA wax alcohol acyltransferase 2 Long-wave-sensitive opsin 1 Medium-wave-sensitive opsin 1 Retinaldehyde-binding protein 1 Retinol-binding protein 3 Short-chain dehydrogenase/reductase 3 Short-wave-sensitive opsin 1	O75911 P03999 P04000 P04001 P10745 P12271 Q6E213	AWAT2 BCP CRALBP DC4 DGAT2L4 DHRS3 GCP MFAT OPN1LW OPN1MW OPN1SW RBP3 RCP RDH17 RLBP1 SDR16C1 WS	Homo sapiens (human)
The role of GTSE1 in G2/M progression after G2 checkpoint	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Cellular tumor antigen p53 Cyclin-dependent kinase 1 Cyclin-dependent kinase inhibitor 1 FK506-binding protein-like G2 and S phase-expressed protein 1 G2/mitotic-specific cyclin-B1 G2/mitotic-specific cyclin-B2 Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Microtubule-associated protein RP/EB family member 1 Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Serine/threonine-protein kinase PLK1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A5LHX3 O00231 O00232 O00233 O00487 O14818 O43242 O75832 O95067 P04637 P06493 P07900 P08238 P0CG47 P0CG48 P14635 P17980 P20618 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P35998 P38936 P40306 P43686 P48556 P49720 P49721 P51665 P53350 P55036 P60896 P60900 P61289 P62191 P62195 P62333 P62979 P62987 Q06323 Q13200 Q14997 Q15008 Q15691 Q16401 Q8TAA3 Q92530 Q99436 Q99460 Q9NYZ3 Q9UIM3 Q9UL46 Q9UNM6	C7orf76 CAP20 CCNB CCNB1 CCNB2 CDC2 CDC28A CDK1 CDKN1 CDKN1A CIP1 DIR1 DSS1 FKBPL GTSE1 HC2 HC3 HC8 HC9 HSP90A HSP90AA1 HSP90AB1 HSP90B HSPC HSPC1 HSPC2 HSPC3 HSPCA HSPCB IFI5111 KIAA0072 KIAA0077 KIAA0107 LMP10 LMP2 LMP7 LMPX LMPY MAPRE1 MB1 MCB1 MDA6 MECL1 MIP224 MOV34L MSS1 NG7 NU P34CDC2 P53 PFAAP4 PIC1 PLK PLK1 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 RING10 RING12 RPS27A SDI1 SEM1 SHFDG1 SHFM1 SUG1 SUG2 TBP1 TBP7 TP53 TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 WAF1 X Y Y2 Z	Homo sapiens (human)
Thrombin signalling through proteinase activated receptors (PARs)	Beta-arrestin-1 Beta-arrestin-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(q) subunit alpha Guanine nucleotide-binding protein subunit alpha-11 Guanine nucleotide-binding protein subunit alpha-12 Guanine nucleotide-binding protein subunit alpha-13 Guanine nucleotide-binding protein subunit alpha-14 Guanine nucleotide-binding protein subunit alpha-15 Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Proteinase-activated receptor 1 Proteinase-activated receptor 3 Proteinase-activated receptor 4 Prothrombin	O00254 O14610 O14775 O60262 O95837 P00734 P16520 P25116 P27361 P28482 P29992 P30679 P32121 P49407 P50148 P50150 P50151 P59768 P61952 P62873 P62879 P63211 P63215 P63218 Q03113 Q14344 Q96RI0 Q9HAV0 Q9P2W3 Q9UBI6 Q9UK08	ARB2 ARR1 ARR2 ARRB1 ARRB2 CF2R ERK1 ERK2 F2 F2R F2RL2 F2RL3 GA11 GAQ GNA11 GNA12 GNA13 GNA14 GNA15 GNA16 GNAQ GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 MAPK1 MAPK3 PAR1 PAR3 PAR4 PRKM1 PRKM2 PRKM3 TR	Homo sapiens (human)
Thromboxane signalling through TP receptor	Angio-associated migratory cell protein Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(q) subunit alpha Guanine nucleotide-binding protein subunit alpha-11 Guanine nucleotide-binding protein subunit alpha-13 Guanine nucleotide-binding protein subunit alpha-14 Guanine nucleotide-binding protein subunit alpha-15 Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Thromboxane A2 receptor	O14610 O14775 O60262 O95837 P16520 P21731 P29992 P30679 P50148 P50150 P50151 P59768 P61952 P62873 P62879 P63211 P63215 P63218 Q13685 Q14344 Q9HAV0 Q9P2W3 Q9UBI6 Q9UK08	AAMP GA11 GAQ GNA11 GNA13 GNA14 GNA15 GNA16 GNAQ GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 TBXA2R	Homo sapiens (human)
Thyroxine biosynthesis	Dual oxidase 1 Dual oxidase 2 Glycoprotein hormones alpha chain Iodotyrosine deiodinase 1 Sodium/iodide cotransporter Thyroid peroxidase Thyrotropin subunit beta	P01215 P01222 P07202 Q6PHW0 Q92911 Q9NRD8 Q9NRD9	C6orf71 CGA DEHAL1 DUOX DUOX1 DUOX2 IYD LNOX1 LNOX2 NIS SLC5A5 THOX1 THOX2 TPO TSHB	Homo sapiens (human)
Tie2 Signaling	Angiopoietin-1 receptor Angiopoietin-1 Angiopoietin-2 Angiopoietin-4 Docking protein 2 GTPase HRas GTPase NRas Growth factor receptor-bound protein 14 Growth factor receptor-bound protein 7 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform SHC-transforming protein 1 Son of sevenless homolog 1 Tyrosine-protein phosphatase non-receptor type 11	O00459 O15123 O60496 P01111 P01112 P27986 P29353 P42336 P42338 Q02763 Q06124 Q07889 Q14449 Q14451 Q15389 Q9Y264	ANG3 ANG4 ANGPT1 ANGPT2 ANGPT4 DOK2 GRB1 GRB14 GRB7 HRAS HRAS1 KIAA0003 NRAS PIK3C1 PIK3CA PIK3CB PIK3R1 PIK3R2 PTP2C PTPN11 SHC SHC1 SHCA SHPTP2 SOS1 TEK TIE2 VMCM VMCM1	Homo sapiens (human)
Tight junction interactions	Claudin-10 Claudin-11 Claudin-12 Claudin-14 Claudin-15 Claudin-16 Claudin-17 Claudin-18 Claudin-19 Claudin-1 Claudin-20 Claudin-22 Claudin-23 Claudin-2 Claudin-3 Claudin-4 Claudin-5 Claudin-6 Claudin-7 Claudin-8 Claudin-9 Envelope small membrane protein InaD-like protein Junctional adhesion molecule A Partitioning defective 3 homolog Partitioning defective 6 homolog alpha Partitioning defective 6 homolog beta Partitioning defective 6 homolog gamma Protein PALS1 Protein crumbs homolog 3 Protein kinase C iota type	O00501 O14493 O15551 O75508 O95471 O95484 O95500 O95832 P0DTC4 P41743 P56746 P56747 P56748 P56749 P56750 P56856 P56880 P57739 P78369 Q8N3R9 Q8N6F1 Q8N7P3 Q8NI35 Q8TEW0 Q96B33 Q9BUF7 Q9BYG4 Q9BYG5 Q9NPB6 Q9Y5I7 Q9Y624	AWAL C7orf1 CEPTRL2 CIPP CLD1 CLDN1 CLDN10 CLDN11 CLDN12 CLDN14 CLDN15 CLDN16 CLDN17 CLDN18 CLDN19 CLDN2 CLDN20 CLDN22 CLDN23 CLDN3 CLDN4 CLDN5 CLDN6 CLDN7 CLDN8 CLDN9 CPER CPETR1 CPETR2 CPETRL2 CRB3 DXS1179E E F11R INADL JAM1 JCAM MPP5 OSP OTM PALS1 PAR3 PAR3A PAR6A PAR6B PAR6G PARD3 PARD6A PARD6B PARD6G PATJ PCLN1 PRKCI SEMP1 TMVCF WBSCR8	Homo sapiens (human)

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