GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **676 - 700** of **1070** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism ▼	GlyTouCan ID
Cilium Assembly	Alpha-tubulin N-acetyltransferase 1	Q6MG11	Atat1 Mec17	Rattus norvegicus (Norway rat)
Toll Like Receptor 4 (TLR4) Cascade	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 Bactericidal permeability-increasing protein CD180 molecule Dynamin-1 Dynamin-2 Dynamin-3 Lipopolysaccharide-binding protein Lymphocyte antigen 86 Lymphocyte antigen 96 Monocyte differentiation antigen CD14 TIR domain containing adaptor molecule 2 Toll-like receptor 4 Tyrosine-protein phosphatase non-receptor type	D3ZAS0 D3ZIP2 D3ZXR7 G3V6B9 P21575 P24135 P39052 Q08877 Q56DL5 Q63313 Q63691 Q6AXU0 Q9QX05	Bpi Cd14 Cd180 Dnm Dnm1 Dnm2 Dnm3 Dyn2 Dyn3 Lbp Ly86 Ly96 Plcg2 Ptpn4 Ticam2 Tlr4	Rattus norvegicus (Norway rat)
Adherens junctions interactions	Afadin Angiogenin ribonuclease 2 Cadherin 10 Cadherin 11 Cadherin 12 Cadherin 13 Cadherin 15 Cadherin 18 Cadherin 24 Cadherin 3 Cadherin 9 Cadherin-17 Cadherin-1 Cadherin-2 Cadherin-5 Cadherin-6 Cadherin-7 Cadherin-8 Cell adhesion molecule 1 Cell adhesion molecule 2 Cell adhesion molecule 3 Nectin cell adhesion molecule 1 Nectin cell adhesion molecule 2 Nectin cell adhesion molecule 3 Nectin cell adhesion molecule 4	A0A0G2K0I6 A0A8I5YBQ6 A0A8I5ZU75 A0A8I6AM66 A0A8I6G502 D3ZFQ5 D3ZTI3 F1LMI3 F1LNP8 F1LR98 F1M1A2 F1M702 F1MAH6 O35889 O54800 P55280 P55281 Q1WIM2 Q1WIM3 Q5DWV2 Q5FVC5 Q5GAM5 Q6AYP5 Q9R0T4 Q9Z1Y3	Af6 Afdn Ang Ang2 Cad7 Cadm1 Cadm2 Cadm3 Cdh1 Cdh10 Cdh11 Cdh12 Cdh13 Cdh15 Cdh17 Cdh18 Cdh2 Cdh24 Cdh3 Cdh5 Cdh6 Cdh7 Cdh8 Cdh9 Igsf4b Igsf4d Kcad Mllt4 Necl1 Necl3 Nectin1 Nectin2 Nectin3 Nectin4 Pvrl1 Pvrl2 Raa2 SynCam1	Rattus norvegicus (Norway rat)
Other interleukin signaling	Caspase-3 Interleukin-34 Macrophage colony-stimulating factor 1 receptor Macrophage colony-stimulating factor 1 Pro-interleukin-16 Receptor-type tyrosine-protein phosphatase zeta Synaptosomal-associated protein 25 Syndecan-1 Syntaxin-1A Syntaxin-3 Syntaxin-4 Syntaxin-binding protein 2 T-cell surface glycoprotein CD4 Taxilin alpha Vesicle-associated membrane protein 2	A0A8I6AF93 B2GV14 P05540 P26260 P32851 P55213 P60881 P63045 Q00495 Q08849 Q08850 Q4KM46 Q62656 Q62753 Q8JZQ0	Casp3 Cd4 Cpp32 Csf1 Csf1r Csfm Csfmr Fms IL16 Il16 Il34 Ptprz Ptprz1 Ptpz Sap Sdc1 Snap Snap25 Stx1a Stx3 Stx3a Stx4 Stx4a Stxbp2 Syb2 Synd1 Txlna Unc18b Vamp2	Rattus norvegicus (Norway rat)
Extra-nuclear estrogen signaling	72 kDa type IV collagenase Amphiregulin Betacellulin Calmodulin-3 Caveolin-1 Caveolin-2 Estrogen receptor beta Estrogen receptor Focal adhesion kinase 1 Guanine nucleotide-binding protein G(i) subunit alpha-1 Guanine nucleotide-binding protein G(i) subunit alpha-2 Guanine nucleotide-binding protein G(i) subunit alpha-3 Guanine nucleotide-binding protein G(t) subunit alpha-3 Heat shock protein HSP 90-alpha Insulin-like growth factor 1 receptor Matrilysin Matrix metalloproteinase-9 Nitric oxide synthase 3 Palmitoyltransferase ZDHHC7 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 3-kinase regulatory subunit gamma Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Pro-epidermal growth factor Proepiregulin Proheparin-binding EGF-like growth factor Protein arginine N-methyltransferase 1 Proto-oncogene tyrosine-protein kinase Src Protransforming growth factor alpha RAC-alpha serine/threonine-protein kinase Receptor protein-tyrosine kinase SHC-transforming protein 1 Sphingosine kinase 1 Sphingosine-1-phosphate receptor 3 Striatin Stromelysin-1	A0A0G2K344 A0A8I6AQ55 F1M9D3 G3V6K6 O35346 P01134 P03957 P04897 P06211 P07522 P08753 P0DP31 P10824 P24062 P24338 P29348 P33436 P41350 P47196 P50280 P50282 P70483 P82995 Q06175 Q2IBC5 Q5M824 Q62600 Q62986 Q63009 Q63787 Q63788 Q63789 Q91V26 Q923G5 Q9WUD9 Q9Z0L5	Akt1 Areg Btc CaMIII Calm3 Cam3 Camc Cav Cav1 Cav2 Dtr Egf Egfr Erbeta Ereg Esr Esr1 Esr2 Estr Fak Fak1 Gnai-1 Gnai-2 Gnai-3 Gnai1 Gnai2 Gnai3 Gnat-3 Gnat3 Hbegf Hegfl Hrmt1l2 Hsp86 Hsp90aa1 Hspca Igf1r Mmp-7 Mmp2 Mmp3 Mmp7 Mmp9 Nos3 Nr3a1 Nr3a2 Pik3ca Pik3r1 Pik3r2 Pik3r3 Prmt1 Ptk2 S1pr3 Sdgf Serz Shc1 Sphk1 Src Strn Tgfa Zdhhc7	Rattus norvegicus (Norway rat)
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function	ASH2 like histone lysine methyltransferase complex subunit Core-binding factor subunit beta Erythroid transcription factor Histone H2A type 2-A Histone H2A.J Histone H2A Histone H2A Histone H2A Histone H2A Histone H2A Histone H2A Histone H2B type 1-A Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H3.1 Histone H3.3 Histone H3 Histone H4 Histone acetyltransferase Histone deacetylase 1 Histone-lysine N-methyltransferase Protein arginine N-methyltransferase 1 RB binding protein 5, histone lysine methyltransferase complex subunit Runt-related transcription factor 1 SET domain containing 1A, histone lysine methyltransferase SET domain containing 1B, histone lysine methyltransferase SIN3 transcription regulator family member A SIN3 transcription regulator family member B WD repeat-containing protein 5 Zinc finger protein, multitype 1 [histone H3]-lysine(4) N-methyltransferase [histone H3]-lysine(4) N-methyltransferase histone acetyltransferase	A0A0G2JXI9 A0A0G2K1E3 A0A0G2K6T6 A0A8I5Y222 A0A8I5ZSA8 A0A8I5ZYY0 A0A8I6A2W1 A0A8I6A4Z1 A0A8I6A7P3 A0A8I6AFW8 A0A8I6ANV4 A0A8I6AWT3 A0A8I6G641 A0A8I6G659 A0A8I6G8L9 A0A8I6GMB2 A9UMV8 D3ZBP2 D3ZC01 D3ZJ08 D3ZTV7 D3ZVK7 D3ZXP3 D4A168 D4ACM0 F1M0L3 G3V9C7 M0RBQ5 P0CC09 P43429 P62804 P84245 Q00729 Q498M4 Q4QQW4 Q63009 Q63046 Q6LED0	Aml1 Ash2l Cbfa2 Cbfb ENSRNOG00000062927 ENSRNOG00000064540 ENSRNOG00000066901 ENSRNOG00000068034 Ep300 Gata1 H2ab3 H2ac10 H2ac18 H2ac4 H2afb3 H2afx H2aj H2ax H2az2 H2bc1 H2bc12l1 H2bc6 H2bcl1 H2bcl2 H2bu1 H3-3b H3.3b H3c13 H3f3b H4c16 H4c2 H4f16 H4ft Hdac1 Hist1h2ba Hist1h2bc Hist1h2bg Hist1h2bo Hist1h2bq Hist1h4b Hist1h4m Hist2h2aa3 Hist2h3c2 Hist4 Hist4h4 Hrmt1l2 Kat2b Kmt2a Kmt2b Kmt2c LOC100365043 LOC100910200 LOC120097726 LOC684797 Mll Mll1 Prmt1 Rbbp5 Runx1 Setd1a Setd1b Sin3a Sin3b Th2b Wdr5 Zfpm1	Rattus norvegicus (Norway rat)
Presynaptic depolarization and calcium channel opening	Voltage-dependent L-type calcium channel subunit beta-1 Voltage-dependent L-type calcium channel subunit beta-2 Voltage-dependent L-type calcium channel subunit beta-3 Voltage-dependent L-type calcium channel subunit beta-4 Voltage-dependent N-type calcium channel subunit alpha-1B Voltage-dependent P/Q-type calcium channel subunit alpha-1A Voltage-dependent R-type calcium channel subunit alpha-1E Voltage-dependent calcium channel gamma-2 subunit Voltage-dependent calcium channel gamma-4 subunit Voltage-dependent calcium channel subunit alpha-2/delta-2 Voltage-dependent calcium channel subunit alpha-2/delta-3	D4A055 P54282 P54283 P54287 Q02294 Q07652 Q71RJ2 Q8CFG5 Q8CFG6 Q8VGC3 Q8VHW9	Cach4 Cach5 Cach6 Cacn3 Cacna1a Cacna1b Cacna1e Cacna2d2 Cacna2d3 Cacnb1 Cacnb2 Cacnb3 Cacnb4 Cacng2 Cacng4 Cacnl1a4 Cacnl1a5 Cacnl1a6 Cacnlb1 Cacnlb2 Cacnlb3 Stg	Rattus norvegicus (Norway rat)
Loss of Nlp from mitotic centrosomes	14-3-3 protein epsilon 14-3-3 protein gamma A-kinase anchoring protein 9 ALMS1, centrosome and basal body associated protein Alpha-centractin CDK5 regulatory subunit-associated protein 2 Casein kinase I isoform delta Centrin 2 Centriolar coiled-coil protein 110 Centromere protein J Centrosomal protein 131 Centrosomal protein 135 Centrosomal protein 152 Centrosomal protein 164 Centrosomal protein 192 Centrosomal protein 250 Centrosomal protein 290 Centrosomal protein 43 Centrosomal protein 72 Centrosomal protein 78 Centrosomal protein of 41 kDa Centrosomal protein of 57 kDa Centrosomal protein of 63 kDa Centrosomal protein of 70 kDa Centrosomal protein of 76 kDa Cyclin-dependent kinase 1 Cytoplasmic dynein 1 heavy chain 1 Cytoplasmic dynein 1 intermediate chain 2 Cytoplasmic linker associated protein 1 Cytoskeleton associated protein 5 Dynactin 3-like 1 Dynactin subunit 1 Dynactin subunit 2 Dynein light chain 1, cytoplasmic Family with sequence similarity 29, member A HAUS augmin-like complex subunit 1 HAUS augmin-like complex subunit 8 HAUS augmin-like complex, subunit 4 HAUS augmin-like complex, subunit 5 HAUS augmin-like complex, subunit 7 Heat shock protein HSP 90-alpha Microtubule-associated protein RP/EB family member 1 NEDD1 gamma-tubulin ring complex targeting factor Ninein-like Nuclear distribution protein nudE homolog 1 Ofd1 centriole and centriolar satellite protein Outer dense fiber protein 2 Pericentrin Pericentriolar material 1 Platelet-activating factor acetylhydrolase IB subunit alpha Protein phosphatase 2 scaffold subunit A alpha SFI1 centrin binding protein SHH signaling and ciliogenesis regulator SDCCAG8 SS nuclear autoantigen 1 Serine/threonine-protein kinase PLK1 Serine/threonine-protein kinase PLK4 Tubulin alpha-1A chain Tubulin alpha-4A chain Tubulin beta-4B chain Tubulin beta-5 chain Tubulin gamma-1 chain cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase type II-beta regulatory subunit non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase	A0A0G2JYQ1 A0A0G2K4Y6 A0A0G2K548 A0A0G2K929 A0A8I5ZRX6 A0A8I5ZSK7 A0A8I5ZUW5 A0A8I6A1X1 A0A8I6A567 A0A8I6A773 A0A8I6AA62 A0A8I6ACI2 A0A8I6AEZ5 A0A8I6AHQ6 A0A8I6AIV4 A0A8I6ALB1 B2GUY1 B4F7A7 D3ZAH3 D3ZI35 D3ZMY8 D3ZTG6 D3ZVQ1 D4A194 D4A3J9 D4AB06 D4AEL8 F1LP29 F1M7J7 G3V931 G3V9W0 M0R9A9 P12369 P27791 P28023 P38650 P39951 P61983 P62260 P63004 P63170 P68370 P69897 P82995 P83888 P85515 Q06486 Q4KLY0 Q4KM37 Q4V7C1 Q5BK57 Q5PQQ9 Q5XI34 Q5XIF6 Q62673 Q62871 Q66HR2 Q6AYC0 Q6AYH5 Q6AYX5 Q6P9T8 Q99PS2 Q9ES39 Q9JLH5 Q9R0A8	AABR07000222.1 Actr1a Akap9 Alms1 Azi1 Ccdc5 Ccp110 Cdc2 Cdc2a Cdk1 Cdk5rap2 Cdkn1 Cenpj Cep131 Cep135 Cep152 Cep164 Cep192 Cep250 Cep290 Cep41 Cep43 Cep57 Cep63 Cep70 Cep72 Cep76 Cep78 Cetn2 Ck1e-2 Ckap5 Clasp1 Csnk1d Csnk1e Ctrn1 Dctn1 Dctn2 Dctn3l1 Dhc1 Dnch1 Dnchc1 Dnci2 Dncic2 Dncl1 Dnclc1 Dnec1 Dyhc Dync1h1 Dync1i2 Dynll1 Fgfr1op Haus1 Haus4 Haus5 Haus6 Haus7 Haus8 Hckid Hice1 Hsp86 Hsp90aa1 Hspca LOC309692 Lis-1 Lis1 Map1c Mapre1 Nde1 Nedd1 Nek2l1 Ninl Nude Nude1 Ny-sar-48 Odf2 Odf84 Ofd1 Pafah1b1 Pafaha Pcm1 Pcnt Pin Plk Plk1 Plk4 Ppp2r1a Prkaca Prkar2b Sak Sdccag8 Sfi1 Ssna1 Tsga14 Tuba1 Tuba1a Tuba4 Tuba4a Tubb2c Tubb4b Tubb5 Tubg Tubg1 Ywhae Ywhag	Rattus norvegicus (Norway rat)
SHC1 events in ERBB2 signaling	Betacellulin Neuregulin 3 Pro-epidermal growth factor Pro-neuregulin-1, membrane-bound isoform Pro-neuregulin-2, membrane-bound isoform Proepiregulin Proheparin-binding EGF-like growth factor Protein kinase C alpha type Protein kinase C delta type Protein kinase C epsilon type Receptor protein-tyrosine kinase Receptor tyrosine-protein kinase erbB-2 Receptor tyrosine-protein kinase erbB-3 SHC-transforming protein 1 Tyrosine-protein phosphatase non-receptor type 12	A0A8I5Y1H8 A0A8I6AQ55 G3V6K6 G3V7Q4 O35569 P05696 P06494 P07522 P09215 P09216 P43322 Q06175 Q5M824 Q62799 Q9Z0L5	Btc Dtr Egf Egfr Erbb2 Erbb3 Ereg Hbegf Hegfl Ndf Neu Nrg1 Nrg2 Nrg3 Ntak Pkca Pkcd Pkce Prkca Prkcd Prkce Ptpn12 Shc1	Rattus norvegicus (Norway rat)
Ion channel transport	ATPase H+ transporting V0 subunit B ATPase H+ transporting V0 subunit D1 ATPase H+ transporting V1 subunit E2 H(+)-transporting two-sector ATPase V-type proton ATPase 116 kDa subunit a 1 V-type proton ATPase 16 kDa proteolipid subunit c V-type proton ATPase subunit B, brain isoform V-type proton ATPase subunit C 1 V-type proton ATPase subunit C 2 V-type proton ATPase subunit D V-type proton ATPase subunit E 1 V-type proton ATPase subunit F V-type proton ATPase subunit G V-type proton ATPase subunit G V-type proton ATPase subunit G V-type proton ATPase subunit H V-type proton ATPase subunit S1 V-type proton ATPase subunit a V-type proton ATPase subunit a V-type proton ATPase subunit d 2 V-type proton ATPase subunit e 1 V-type proton ATPase subunit e 2 Vacuolar proton pump subunit B	A0A8I5ZND3 A0A8I5ZWI2 A0A8I6B3N3 A0A8J8XD13 D3ZJ78 D3ZTZ4 D3ZZS8 D4A133 D4A1H0 F7FFW7 O54715 P25286 P50408 P62815 P63081 Q5EB76 Q5FVI6 Q5FVL0 Q6AYE4 Q6P503 Q6PCU2 Q794C0 Q8R2H0	Aif1 Atp6ap1 Atp6b2 Atp6c Atp6ip1 Atp6l Atp6n1 Atp6s1 Atp6s14 Atp6v0a1 Atp6v0a4 Atp6v0b Atp6v0c Atp6v0d1 Atp6v0d2 Atp6v0e Atp6v0e1 Atp6v0e2 Atp6v1a Atp6v1b1 Atp6v1b2 Atp6v1c1 Atp6v1c2 Atp6v1d Atp6v1e1 Atp6v1e2 Atp6v1f Atp6v1g1 Atp6v1g2 Atp6v1g3 Atp6v1h Atpl Bat1a Cdk2ap1-ps2 Cdk2ap1-ps3 Cdk2ap1-ps4 Cdk2ap1-ps5 Cdk2ap1-ps6 Dsr1 E230034O05Rik LOC224733l-3 LOC224733l-4 LOC224733l-5 LOC224733l-6 LOC224733l-7 LOC224733l-8 Lst1 RT1-CE12 RT1-CE3 RT1-CE5 RT1-CE6 RT1-CE8 RT1-CE9 Sacm2l-ps3 Sacm2l-ps4 Sacm2l-ps5 Sacm2l-ps6 Sacm2l-ps7 Tcirg1 Tnf Vat2 Vatf Vpp1	Rattus norvegicus (Norway rat)
Fructose catabolism	Aldehyde dehydrogenase 1A1 Fructose-bisphosphate aldolase B Glycerate kinase Ketohexokinase Triokinase/FMN cyclase	P00884 P51647 Q02974 Q0VGK3 Q4KLZ6	Aldh Aldh1a1 Aldob Dak Glyctk Khk Tkfc	Rattus norvegicus (Norway rat)
Interleukin-9 signaling	Interleukin 9 receptor Interleukin 9 Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 4 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Tyrosine-protein kinase JAK3 Tyrosine-protein kinase	A0A0G2JX93 A0A8I6AHK3 A0A8I6AM23 D4A8I9 P52631 P52632 Q62771 Q63272	Il9 Il9r Jak1 Jak3 Mgf Stat1 Stat3 Stat4 Stat5a Stat5b	Rattus norvegicus (Norway rat)
Cytosolic sensors of pathogen-associated DNA	Absent in melanoma 2 Double-strand break repair protein MRE11	D4A9W0 Q9JIM0	Aim2 Mre11 Mre11a	Rattus norvegicus (Norway rat)
MAP2K and MAPK activation	14-3-3 protein beta/alpha Amyloid beta A4 precursor protein-binding family B member 1-interacting protein Beta-arrestin-1 Beta-arrestin-2 Connector enhancer of kinase suppressor of Ras 1 Connector enhancer of kinase suppressor of ras 2 Dual specificity mitogen-activated protein kinase kinase 1 Dual specificity mitogen-activated protein kinase kinase 2 Fibrinogen alpha chain Fibrinogen beta chain Fibrinogen gamma chain Fibronectin GTPase HRas GTPase KRas GTPase NRas IQ motif containing GTPase activating protein 1 Integrin beta-3 Integrin subunit alpha 2b Interleukin 17 receptor D Kinase suppressor of ras 1 Kinase suppressor of ras 2 MAP/microtubule affinity-regulating kinase 3 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Phosphatidylethanolamine-binding protein 1 Proto-oncogene tyrosine-protein kinase Src RAF proto-oncogene serine/threonine-protein kinase Ragulator complex protein LAMTOR3 Ras-related protein Rap-1A Ras-related protein Rap-1b Roadblock/LAMTOR2 domain-containing protein Serine/threonine-protein kinase A-Raf Talin 1 Tyrosine-protein kinase CSK Vinculin WD repeat domain-containing protein 83 non-specific serine/threonine protein kinase	A0A8I5ZQW6 A0A8I6ABG6 A0A8I6ADH7 A0A8I6AI85 A0A8I6ATH0 A0A8I6GGN2 D3ZDZ1 D3ZGQ0 F1LY04 G3V7Q7 P02680 P04937 P06399 P08644 P11345 P14056 P14480 P20171 P21708 P29066 P29067 P31044 P32577 P35213 P36506 P62836 P63086 P85972 Q01986 Q04970 Q5BLX8 Q5U204 Q62636 Q8R2H2 Q8VHF0 Q9WUD9 Q9Z1T4	A-raf Apbb1ip Araf Araf1 Arrb1 Arrb2 Braf Cnksr1 Cnksr2 Csk ENSRNOG00000066475 Erk1 Erk2 Fga Fgb Fgg Fn1 Hras Hras1 Il17rd Iqgap1 Itga2b Itgb3 Kras Kras2 Krev1 Ksr1 Ksr2 Lamtor3 Map2k1 Map2k1ip1 Map2k2 Mapk Mapk1 Mapk3 Mark3 Mek1 Mek2 Mkk2 Morg1 Nras Pbp Pebp Pebp1 Prkm1 Prkm3 Prkmk1 Prkmk2 RGD1562674 Raf Raf1 Rap1a Rap1b Src Tln1 Vcl Wdr83 Ywhab	Rattus norvegicus (Norway rat)
Urea cycle	Arginase-1 Arginase-2, mitochondrial Argininosuccinate lyase Carbamoyl-phosphate synthase [ammonia], mitochondrial Mitochondrial ornithine transporter 1 N-acetylglutamate synthase Ornithine transcarbamylase, mitochondrial Solute carrier family 25 member 2	A0A0G2K309 A0A8I6G8E8 D4A904 O08701 P00481 P07756 P07824 P20673	Arg1 Arg2 Asl Cps1 Nags Otc Slc25a15 Slc25a2	Rattus norvegicus (Norway rat)
IL-6-type cytokine receptor ligand interactions	Cardiotrophin-1 Cardiotrophin-like cytokine factor 1 Ciliary neurotrophic factor receptor subunit alpha Ciliary neurotrophic factor Cytokine receptor-like factor 1 Interleukin 31 receptor A Interleukin 31 Interleukin-11 receptor subunit alpha Interleukin-11 Interleukin-6 receptor subunit beta Leukemia inhibitory factor receptor Leukemia inhibitory factor Oncostatin-M-specific receptor subunit beta Oncostatin-M Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Tyrosine-protein kinase	A0A8I5ZNP8 A0A8I6AM23 A0A8I6GGY9 D3ZD03 D3ZIV9 F1LZR4 O70535 P17777 P20294 P40190 Q08406 Q62689 Q63086 Q65Z14 Q65Z15 Q99MF4 Q99MF5	Clcf1 Cntf Cntfr Crlf1 Ctf1 Il11 Il11ra1 Il31 Il31ra Il6st Jak1 Jak2 Lif Lifr Osm Osmr Osmrb Tyk2	Rattus norvegicus (Norway rat)
CREB phosphorylation	Activating transcription factor 1 Cyclic AMP-responsive element-binding protein 1 MAPK activated protein kinase 2 Ribosomal protein S6 kinase alpha-1 Ribosomal protein S6 kinase Ribosomal protein S6 kinase Ribosomal protein S6 kinase	A0A8I6A7D1 A0A8I6AR08 A0A8I6AWJ2 F7FD47 P15337 Q63531 Q80ZF4	Atf1 Creb-1 Creb1 Mapkapk1a Mapkapk2 Rps6ka1 Rps6ka2 Rps6ka3 Rps6ka5 Rsk1	Rattus norvegicus (Norway rat)
NOTCH3 Activation and Transmission of Signal to the Nucleus	Delta-like protein 1 Delta-like protein 4 Disintegrin and metalloproteinase domain-containing protein 10 E3 ubiquitin-protein ligase Gamma-secretase subunit APH-1 Gamma-secretase subunit PEN-2 Neurogenic locus notch homolog protein 3 Nicastrin Polyubiquitin-B Polyubiquitin-C Presenilin-1 Presenilin-2 Pro-epidermal growth factor Protein jagged-1 Protein jagged-2 (Fragment) Receptor protein-tyrosine kinase Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein	A0A8I6A5Y3 B4F767 D3ZHH1 F7EYZ3 G3V6K6 O88777 P07522 P0CG51 P62982 P97607 P97677 P97887 Q10743 Q63429 Q63722 Q6QI68 Q8CGU6 Q9R172	Adam10 Aph1a Dll1 Dll4 Egf Egfr Jag1 Jag2 LOC100360645 Madm Ncstn Notch3 Ps2 Psen1 Psen2 Psenen Psnl1 Psnl2 Rps27a Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1 Wwp2	Rattus norvegicus (Norway rat)
Gluconeogenesis	Beta-enolase Enolase 4 Fructose-1,6-bisphosphatase 1 Fructose-1,6-bisphosphatase isozyme 2 Fructose-bisphosphate aldolase A Fructose-bisphosphate aldolase B Fructose-bisphosphate aldolase C Gamma-enolase Glucose-6-phosphatase 3 Glucose-6-phosphatase catalytic subunit 1 Glucose-6-phosphate isomerase Glyceraldehyde-3-phosphate dehydrogenase, testis-specific Glyceraldehyde-3-phosphate dehydrogenase Glyceraldehyde-3-phosphate dehydrogenase Phosphoenolpyruvate carboxykinase, cytosolic [GTP] Phosphoglycerate kinase 1 Phosphoglycerate kinase Phosphoglycerate mutase 1 Phosphoglycerate mutase 2 Pyruvate carboxylase, mitochondrial Solute carrier family 37 (Glycerol-3-phosphate transporter), member 1 Solute carrier family 37 member 2 Solute carrier family 37 member 4 Triosephosphate isomerase Triosephosphate isomerase phosphoenolpyruvate carboxykinase (GTP)	A0A0G2JTY3 A0A0G2K6J4 A0A8I5ZVI4 A0A8I6AN31 F1LQJ7 F1LUV3 P00884 P04797 P05065 P07323 P07379 P09117 P15429 P16290 P16617 P19112 P25113 P43428 P48500 P52873 Q5XIV1 Q66H72 Q6AZ83 Q6P6V0 Q9ESV6 Q9Z1N1	Aldoa Aldob Aldoc ENSRNOG00000066746 Eno-2 Eno-3 Eno2 Eno3 Eno4 Fbp Fbp1 Fbp2 G6pc G6pc1 G6pc3 G6pt Gapd Gapd-s Gapdh Gapdhs Gapds Gpi Pc Pck1 Pck2 Pgam1 Pgam2 Pgk-1 Pgk1 Pgk2 RGD1563601 Slc37a1 Slc37a2 Slc37a4 Tpi1 Tpi1l2	Rattus norvegicus (Norway rat)	G58161NS
Phosphorylation of the APC/C	Anaphase promoting complex subunit 1 Anaphase promoting complex subunit 7 Anaphase-promoting complex subunit 15 Anaphase-promoting complex subunit 16 Anaphase-promoting complex subunit 2 Anaphase-promoting complex subunit 4 Anaphase-promoting complex subunit 5 Anaphase-promoting complex subunit CDC26 Cell division cycle 16 Cell division cycle 23 Cell division cycle protein 27 homolog Cyclin-dependent kinase 1 E2 ubiquitin-conjugating enzyme G2/mitotic-specific cyclin-B1 Serine/threonine-protein kinase PLK1 Ubiquitin-conjugating enzyme E2 C Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 S	A0A8I6A4J8 A0A8I6AE10 A0A8I6ANL9 A1L1K3 B5DFI8 D3ZDK2 D3ZDN9 D3ZIT4 D3ZQX4 D3ZUB7 D3ZUW6 F1M3L4 F7EWF8 P30277 P39951 Q4V8A2 Q62673 Q6YDN7	Anapc1 Anapc15 Anapc16 Anapc2 Anapc4 Anapc5 Anapc7 Ccnb1 Cdc16 Cdc2 Cdc23 Cdc26 Cdc27 Cdc2a Cdk1 Cdkn1 LOC100366017 Plk Plk1 Ube2c Ube2d1 Ube2e1 Ube2s	Rattus norvegicus (Norway rat)
Activation of Ca-permeable Kainate Receptor	Calmodulin-3 Disks large homolog 1 Disks large homolog 3 Disks large homolog 4 Glutamate receptor ionotropic, kainate 1 Glutamate receptor ionotropic, kainate 2 Glutamate receptor ionotropic, kainate 3 Glutamate receptor ionotropic, kainate 4 Glutamate receptor ionotropic, kainate 5 Neurocalcin-delta	P0DP31 P22756 P31016 P42260 P42264 Q01812 Q5PQN0 Q62696 Q62936 Q63273	CaMIII Calm3 Cam3 Camc Dlg1 Dlg3 Dlg4 Dlgh1 Dlgh3 Dlgh4 Glur5 Glur6 Glur7 Grik1 Grik2 Grik3 Grik4 Grik5 Ncald Psd95	Rattus norvegicus (Norway rat)
SHC-related events triggered by IGF1R	Growth factor receptor-bound protein 2 Insulin-like growth factor 1 receptor Insulin-like growth factor I Insulin-like growth factor II SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1	D4A3T0 P01346 P08025 P24062 P62994 Q5M824	Ash Grb2 Igf-1 Igf-2 Igf1 Igf1r Igf2 Shc1 Sos1	Rattus norvegicus (Norway rat)
Sodium-coupled sulphate, di- and tri-carboxylate transporters	Na(+)/citrate cotransporter Na(+)/dicarboxylate cotransporter 3 Sodium sulfate cotransporter-2 Solute carrier family 13 member 1 Solute carrier family 13 member 2	P70545 Q07782 Q5EC47 Q8CJ44 Q9Z0Z5	Nact Nadc1 Nadc3 Nas1 Nasi1 Sdct1 Sdct2 Slc13a1 Slc13a2 Slc13a3 Slc13a4 Slc13a5	Rattus norvegicus (Norway rat)
Regulation by c-FLIP	CASP8 and FADD-like apoptosis regulator Caspase-8 FAS-associated death domain protein Receptor interacting serine/threonine kinase 1 TNF receptor superfamily member 10b TNF receptor-associated factor Tumor necrosis factor ligand superfamily member 6 Tumor necrosis factor ligand superfamily member Tumor necrosis factor receptor superfamily member 6 Tumor necrosis factor receptor type 1-associated DEATH domain protein	A0A0G2JZE1 A0A0U5J7B5 B5DFH7 C0H5Y5 D3ZYL0 D3ZZC5 P36940 Q63199 Q8R2E7 Q9JHX4	AABR07018323.1 Apt1 Apt1Lg1 Casp8 Cd95l Cflar Fadd Fas Fasl Faslg Ripk1 Tnfrsf10b Tnfrsf6 Tnfsf10 Tnfsf6 Tnlg6a Tradd Traf2	Rattus norvegicus (Norway rat)
Nonhomologous End-Joining (NHEJ)	BRCA1-A complex subunit Abraxas 1 BRCA1-A complex subunit RAP80 BRCA1-associated RING domain protein 1 BRISC and BRCA1-A complex member 1 BRISC and BRCA1-A complex member 2 Breast cancer type 1 susceptibility protein homolog DNA ligase DNA polymerase lambda DNA repair protein RAD50 DNA-dependent protein kinase catalytic subunit DNA-directed DNA/RNA polymerase mu Double-strand break repair protein MRE11 E3 ubiquitin-protein ligase RNF168 E3 ubiquitin-protein ligase RNF8 HECT-type E3 ubiquitin transferase Histone H2A Histone H2B type 1-A Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H4 Histone acetyltransferase KAT5 Lys-63-specific deubiquitinase BRCC36 Mediator of DNA damage checkpoint protein 1 Nibrin Non-homologous end-joining factor 1 Nuclear receptor binding SET domain protein 2 PAX-interacting protein 1 Protein artemis Protein inhibitor of activated STAT, 4 Replication timing regulatory factor 1 Serine-protein kinase ATM Tumor protein p53 binding protein 1 Tyrosyl-DNA phosphodiesterase 1 Tyrosyl-DNA phosphodiesterase 2 Ubiquitin-conjugating enzyme E2 variant 2 X-ray repair cross complementing 4 X-ray repair cross complementing 6 X-ray repair cross-complementing protein 5	A0A0G2JUC9 A0A0G2JXI9 A0A8I5Y5Z6 A0A8I5ZSA8 A0A8I5ZSS0 A0A8I6A2W1 A0A8I6A7P3 A0A8I6AFW8 A0A8I6AHX2 B2RYM5 B2RYR0 B5DFF9 D3ZSX6 D3ZTN0 D3ZXP3 D4A0U6 D4A9J4 D4ACL8 F1M842 F7F6Z7 G3V817 G3V9C7 M0RBQ5 O54952 P62804 Q00729 Q3T1H5 Q4G056 Q4KLN8 Q5I0F1 Q5PQK4 Q5RKI3 Q5U2M8 Q5XIJ6 Q5XIX3 Q6AYI4 Q6P7Q1 Q7M767 Q99MK2 Q9JIL8 Q9JIL9 Q9JIM0 Q9QZH2	ABRAXAS1 Abra1 Atm Babam1 Babam2 Bard1 Brca1 Brcc3 Brcc36 Bre Ccdc98 Dclre1c ENSRNOG00000064540 ENSRNOG00000066901 ENSRNOG00000068034 Fam175a H2afx H2ax H2bc1 H2bc12l1 H2bc6 H2bcl1 H2bcl2 H2bu1 H4c16 H4c2 H4f16 H4ft Herc2 Hist1h2ba Hist1h2bc Hist1h2bg Hist1h2bo Hist1h2bq Hist1h4b Hist1h4m Hist4 Hist4h4 Htatip Kat5 LOC100365043 LOC100910200 LOC684797 Lig4 Mdc1 Merit40 Mms2 Mre11 Mre11a Nba1 Nbn Nbs1 Nhej1 Nsd2 Paxip1 Pias4 Poll Polm Prkdc Rad50 Rap80 Rif1 Rnf168 Rnf8 Snm1l Tdp1 Tdp2 Th2b Tip60 Tip60b Tp53bp1 Ttrap Ube2v2 Uev2 Uimc1 Whsc1 Xlf Xrcc4 Xrcc5 Xrcc6	Rattus norvegicus (Norway rat)

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