GlyCosmos Portal

Homo sapiens (human)

Summary

Taxonomy ID: 9606
PubChem Taxonomy: 9606

Genes (1582) Glycans (5831) Glycoproteins (18496) Lectins (298) Pathways (2090)

Displaying entries **801 - 825** of **2090** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▲
Retrograde transport at the Trans-Golgi-Network	ADP-ribosylation factor-like protein 1 ADP-ribosylation factor-related protein 1 Alpha-soluble NSF attachment protein Arfaptin-2 Beta-soluble NSF attachment protein Cation-dependent mannose-6-phosphate receptor Cation-independent mannose-6-phosphate receptor Conserved oligomeric Golgi complex subunit 1 Conserved oligomeric Golgi complex subunit 2 Conserved oligomeric Golgi complex subunit 3 Conserved oligomeric Golgi complex subunit 4 Conserved oligomeric Golgi complex subunit 5 Conserved oligomeric Golgi complex subunit 6 Conserved oligomeric Golgi complex subunit 7 Conserved oligomeric Golgi complex subunit 8 GRIP and coiled-coil domain-containing protein 1 GRIP and coiled-coil domain-containing protein 2 Gamma-soluble NSF attachment protein Golgin subfamily A member 1 Golgin subfamily A member 4 Guanine nucleotide exchange factor subunit RIC1 N-alpha-acetyltransferase 30 N-alpha-acetyltransferase 35, NatC auxiliary subunit N-alpha-acetyltransferase 38, NatC auxiliary subunit Perilipin-3 Protein SYS1 homolog RAB6A-GEF complex partner protein 2 Rab9 effector protein with kelch motifs Ras-related protein Rab-43 Ras-related protein Rab-6A Ras-related protein Rab-6B Ras-related protein Rab-9A Ras-related protein Rab-9B Rho-related BTB domain-containing protein 3 Short coiled-coil protein Syntaxin-10 Syntaxin-16 Syntaxin-6 TATA element modulatory factor Trans-Golgi network integral membrane protein 2 USP6 N-terminal-like protein Vacuolar protein sorting-associated protein 51 homolog Vacuolar protein sorting-associated protein 52 homolog Vacuolar protein sorting-associated protein 53 homolog Vacuolar protein sorting-associated protein 54 Vesicle transport through interaction with t-SNAREs homolog 1A Vesicle-associated membrane protein 3 Vesicle-associated membrane protein 4 Vesicle-fusing ATPase	O14662 O43493 O43752 O60499 O60664 O75379 O94955 P11717 P20340 P20645 P40616 P46459 P51151 P53365 P54920 P82094 P83436 Q13439 Q13795 Q14746 Q147X3 Q15836 Q4ADV7 Q5VIR6 Q5VZE5 Q7Z6M1 Q86YS6 Q8IWJ2 Q8N1B4 Q8N2H4 Q8WTW3 Q92546 Q92738 Q92805 Q96AJ9 Q96CN9 Q96JB2 Q96MW5 Q99747 Q9BRA0 Q9H115 Q9H9E3 Q9NP90 Q9NRW1 Q9P1Q0 Q9UID3 Q9UIL1 Q9UP83 Q9Y2V7	ANG2 ARA160 ARFIP2 ARFRP1 ARL1 ARP1 C11orf2 C11orf3 C14orf35 C20orf169 CIP150 COG1 COG2 COG3 COG4 COG5 COG6 COG7 COG8 EGAP FFR GCC1 GCC2 GOLGA1 GOLGA4 GOLTC1 GTC90 HCC8 IGF2R KIAA0019 KIAA0258 KIAA0336 KIAA0878 KIAA1134 KIAA1381 KIAA1432 LDLB LDLC LSMD1 M6PR M6PRBP1 MAK10 MAK3 MAK31 MPR46 MPRD MPRI NAA30 NAA35 NAA38 NAPA NAPB NAPG NAT12 NSF PFAAP2 PLIN3 POR1 RAB41 RAB43 RAB6 RAB6A RAB6B RAB9 RAB9A RAB9B RAB9L RAB9P40 RABEPK RANBP2L4 RGP1 RHOBTB3 RIC1 SACM2L SCOC SCOCO SEC34 SNAPA SNAPB SNAPG STX10 STX16 STX6 SYB3 SYN10 SYS1 TGN46 TGN51 TGOLN2 TIP47 TMF1 USP6NL VAMP3 VAMP4 VPS51 VPS52 VPS53 VPS54 VTI1A
Tie2 Signaling	Angiopoietin-1 receptor Angiopoietin-1 Angiopoietin-2 Angiopoietin-4 Docking protein 2 GTPase HRas GTPase NRas Growth factor receptor-bound protein 14 Growth factor receptor-bound protein 7 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform SHC-transforming protein 1 Son of sevenless homolog 1 Tyrosine-protein phosphatase non-receptor type 11	O00459 O15123 O60496 P01111 P01112 P27986 P29353 P42336 P42338 Q02763 Q06124 Q07889 Q14449 Q14451 Q15389 Q9Y264	ANG3 ANG4 ANGPT1 ANGPT2 ANGPT4 DOK2 GRB1 GRB14 GRB7 HRAS HRAS1 KIAA0003 NRAS PIK3C1 PIK3CA PIK3CB PIK3R1 PIK3R2 PTP2C PTPN11 SHC SHC1 SHCA SHPTP2 SOS1 TEK TIE2 VMCM VMCM1
Assembly of active LPL and LIPC lipase complexes	Angiopoietin-like protein 8 Angiopoietin-related protein 3 Angiopoietin-related protein 4 Apolipoprotein A-IV Apolipoprotein A-V Apolipoprotein C-II Cyclic AMP-responsive element-binding protein 3-like protein 3 Fibroblast growth factor 21 Furin Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 Hepatic triacylglycerol lipase Lipase maturation factor 1 Lipase maturation factor 2 Lipoprotein lipase Membrane-bound transcription factor site-1 protease Membrane-bound transcription factor site-2 protease Proprotein convertase subtilisin/kexin type 5 Proprotein convertase subtilisin/kexin type 6	O43462 P02655 P06727 P06858 P09958 P11150 P29122 Q14703 Q68CJ9 Q6Q788 Q6UXH0 Q8IV16 Q92824 Q96S06 Q9BU23 Q9BY76 Q9NSA1 Q9Y5C1	ANGPT5 ANGPTL3 ANGPTL4 ANGPTL8 APC2 APOA4 APOA5 APOC2 ARP4 C16orf26 C19orf80 CREB3L3 CREBH FGF21 FUR FURIN GPIHBP1 HBP1 HFARP HTGL KIAA0091 LIPC LIPD LMF1 LMF2 LPL MBTPS1 MBTPS2 PACE PACE4 PC5 PC6 PCSK3 PCSK5 PCSK6 PGAR RAP3 RIFL S1P S2P SKI1 TMEM112 TMEM112B TMEM153
LXRs regulate gene expression linked to lipogenesis	Angiopoietin-related protein 3 Fatty acid synthase Nuclear receptor-interacting protein 1 Oxysterols receptor LXR-alpha Oxysterols receptor LXR-beta Retinoic acid receptor RXR-alpha Retinoic acid receptor RXR-beta Stearoyl-CoA desaturase	O00767 P19793 P28702 P48552 P49327 P55055 Q13133 Q9Y5C1	ANGPT5 ANGPTL3 FADS5 FAS FASN LXRA LXRB NER NR1H2 NR1H3 NR2B1 NR2B2 NRIP1 RXRA RXRB SCD SCD1 SCDOS UNR
Interaction between L1 and Ankyrins	Ankyrin-1 Ankyrin-2 Ankyrin-3 Neural cell adhesion molecule L1 Neurofascin Neuronal cell adhesion molecule Potassium voltage-gated channel subfamily KQT member 2 Potassium voltage-gated channel subfamily KQT member 3 Sodium channel protein type 1 subunit alpha Sodium channel protein type 10 subunit alpha Sodium channel protein type 11 subunit alpha Sodium channel protein type 2 subunit alpha Sodium channel protein type 3 subunit alpha Sodium channel protein type 4 subunit alpha Sodium channel protein type 5 subunit alpha Sodium channel protein type 7 subunit alpha Sodium channel protein type 8 subunit alpha Sodium channel protein type 9 subunit alpha Sodium channel regulatory subunit beta-3 Sodium channel subunit beta-1 Sodium channel subunit beta-2 Sodium channel subunit beta-4 Spectrin alpha chain, erythrocytic 1 Spectrin alpha chain, non-erythrocytic 1 Spectrin beta chain, erythrocytic Spectrin beta chain, non-erythrocytic 1 Spectrin beta chain, non-erythrocytic 2 Spectrin beta chain, non-erythrocytic 4 Spectrin beta chain, non-erythrocytic 5	O15020 O43525 O43526 O60939 O94856 P02549 P11277 P16157 P32004 P35498 P35499 Q01082 Q01118 Q01484 Q07699 Q12955 Q13813 Q14524 Q15858 Q8IWT1 Q92823 Q99250 Q9H254 Q9NRC6 Q9NY46 Q9NY72 Q9UI33 Q9UQD0 Q9Y5Y9	ANK ANK1 ANK2 ANK3 ANKB BSPECV CAML1 HBA HUBSPECV HUSPECV KCNQ2 KCNQ3 KIAA0302 KIAA0343 KIAA0756 KIAA1158 KIAA1356 KIAA1642 L1CAM MED MIC5 NAC1 NAC2 NAC3 NEAS NENA NFASC NRCAM SCA5 SCN1 SCN10A SCN11A SCN12A SCN1A SCN1B SCN2A SCN2A1 SCN2A2 SCN2B SCN3A SCN3B SCN4A SCN4B SCN5A SCN6A SCN7A SCN8A SCN9A SNS2 SPTA SPTA1 SPTA2 SPTAN1 SPTB SPTB1 SPTB2 SPTBN1 SPTBN2 SPTBN3 SPTBN4 SPTBN5
NrCAM interactions	Ankyrin-1 Contactin-2 Disks large homolog 1 Disks large homolog 3 Disks large homolog 4 Neuronal cell adhesion molecule Neuropilin-2	O60462 P16157 P78352 Q02246 Q12959 Q92796 Q92823	ANK ANK1 AXT CNTN2 DLG1 DLG3 DLG4 KIAA0343 KIAA1232 NRCAM NRP2 PSD95 TAG1 TAX1 VEGF165R2
CHL1 interactions	Ankyrin-1 Contactin-6 Heat shock cognate 71 kDa protein Integrin alpha-10 Integrin alpha-1 Integrin alpha-2 Integrin beta-1 Neural cell adhesion molecule L1-like protein Neuropilin-1	O00533 O14786 O75578 P05556 P11142 P16157 P17301 P56199 Q9UQ52	ANK ANK1 CALL CD49B CHL1 CNTN6 FNRB HSC70 HSP73 HSPA10 HSPA8 ITGA1 ITGA10 ITGA2 ITGB1 MDF2 MSK12 NRP NRP1 VEGF165R
Neurofascin interactions	Ankyrin-1 Contactin-1 Contactin-associated protein 1 Neurofascin Neuronal cell adhesion molecule Neuronal migration protein doublecortin Syntenin-1	O00560 O43602 O94856 P16157 P78357 Q12860 Q92823	ANK ANK1 CASPR CNTN1 CNTNAP1 DBCN DCX KIAA0343 KIAA0756 LISX MDA9 NFASC NRCAM NRXN4 SDCBP SYCL
RHOG GTPase cycle	10 kDa heat shock protein, mitochondrial ADP-ribosylation factor GTPase-activating protein 3 Ankyrin repeat and LEM domain-containing protein 2 Caveolin-1 Cdc42 effector protein 1 Cell division control protein 42 homolog Cell surface glycoprotein MUC18 Cytoplasmic FMR1-interacting protein 1 DEP domain-containing protein 1B Dedicator of cytokinesis protein 1 Dedicator of cytokinesis protein 2 Dedicator of cytokinesis protein 3 Dedicator of cytokinesis protein 4 Dedicator of cytokinesis protein 5 Delta(14)-sterol reductase LBR Desmoglein-2 Emerin Engulfment and cell motility protein 2 Ephrin type-A receptor 2 Erbin Extended synaptotagmin-1 Granule associated Rac and RHOG effector protein 1 Guanine nucleotide exchange factor DBS Guanine nucleotide exchange factor VAV2 Guanine nucleotide exchange factor VAV3 Inner nuclear membrane protein Man1 Integrin beta-1 Intersectin-1 Kalirin Kinectin Lamina-associated polypeptide 2, isoforms beta/gamma MAGUK p55 subfamily member 7 Membrane-associated progesterone receptor component 2 Mitochondrial proton/calcium exchanger protein Mitogen-activated protein kinase kinase kinase 11 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial Oligophrenin-1 Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein Phosphatidylinositol 3-kinase regulatory subunit alpha Phospholipase D1 Pleckstrin homology domain-containing family G member 3 Protein ERGIC-53 Protein diaphanous homolog 3 Proto-oncogene DBL Proto-oncogene vav Ragulator complex protein LAMTOR1 Ras GTPase-activating-like protein IQGAP2 Ras-related protein Rab-7a Rho GDP-dissociation inhibitor 1 Rho GDP-dissociation inhibitor 2 Rho GDP-dissociation inhibitor 3 Rho GTPase-activating protein 1 Rho GTPase-activating protein 21 Rho GTPase-activating protein 32 Rho GTPase-activating protein 35 Rho GTPase-activating protein 39 Rho GTPase-activating protein 5 Rho guanine nucleotide exchange factor 16 Rho guanine nucleotide exchange factor 26 Rho guanine nucleotide exchange factor 5 Rho-related GTP-binding protein RhoG Serine hydroxymethyltransferase, mitochondrial Serine/threonine-protein kinase PAK 2 Serine/threonine-protein kinase PAK 4 Serine/threonine-protein kinase VRK2 Starch-binding domain-containing protein 1 Synaptobrevin homolog YKT6 Syntaxin-5 Transferrin receptor protein 1 Triple functional domain protein Vang-like protein 1 Vesicle-associated membrane protein 3 Vesicle-associated membrane protein-associated protein B/C	A1L390 A7KAX9 O15063 O15068 O15173 O15498 O60229 O60890 O75489 O75962 O95202 O95210 O95292 O96013 P02786 P05556 P10911 P15498 P27986 P29317 P34897 P42167 P43121 P49257 P50402 P51149 P52565 P52566 P52735 P60953 P61604 P84095 Q00587 Q03135 Q07960 Q12774 Q13017 Q13177 Q13190 Q13393 Q13576 Q14126 Q14185 Q14739 Q15811 Q15836 Q16584 Q16718 Q5T2T1 Q5T5U3 Q5VV41 Q6IAA8 Q7L576 Q86UP2 Q86XL3 Q86Y07 Q8IZD9 Q8N1I0 Q8TAA9 Q8TCU6 Q8WUY9 Q92608 Q96DR7 Q96JJ3 Q96RT1 Q99819 Q9BSJ8 Q9C0H5 Q9H7D0 Q9NP61 Q9NRY4 Q9NSV4 Q9UKW4 Q9Y2U8	ANKLE2 ARFGAP1 ARFGAP3 ARHG ARHGAP1 ARHGAP10 ARHGAP21 ARHGAP32 ARHGAP35 ARHGAP39 ARHGAP5 ARHGDIA ARHGDIB ARHGDIG ARHGEF16 ARHGEF26 ARHGEF5 BORG5 C11orf59 CAV CAV1 CDC42 CDC42EP1 CDC42GAP CDHF5 CED12A CEP1 CG1 CYFIP1 DBL DEPDC1B DG6 DIAP3 DIAPH3 DOCK1 DOCK2 DOCK3 DOCK4 DOCK5 DSG2 DUET DUO ECK EDMD ELMO2 EMD EPHA2 EPHEXIN4 ERBB2IP ERBIN ERGIC53 ESYT1 F5F8D FAM62A FNRB GARRE1 GDIA1 GDIA2 GDID4 GRB1 GRF1 GRIT GRLF1 HAPIP HSPE1 IQGAP2 ITGB1 ITSN ITSN1 KALRN KIAA0004 KIAA0068 KIAA0209 KIAA0299 KIAA0355 KIAA0362 KIAA0599 KIAA0692 KIAA0712 KIAA0716 KIAA0747 KIAA1142 KIAA1225 KIAA1415 KIAA1424 KIAA1688 KIAA1722 KIAA1834 KTN1 LAMTOR1 LAP2 LBR LEM4 LEMD3 LETM1 LMAN1 MAN1 MAP3K11 MBC2 MCAM MCF2 MCF2L MDF2 MLK3 MOCA MPP7 MSE55 MSK12 MUC18 NBR NDUFA5 NDUFS3 OPHN1 OST P190A PAK2 PAK4 PDRO PGRMC2 PIK3R1 PLD1 PLEKHG3 PMBP PREX1 PTK1 RAB7 RAB7A RAP1GN1 RHOG RHOGAP1 RHOGAP5 RICS SGEF SH3D1A SHMT2 SPRK STA STB2 STBD1 STX5 STX5A SYB3 TFRC TIM TMPO TRAD TRIO VAMP3 VANGL1 VAPB VAV VAV1 VAV2 VAV3 VRK2 XTP8 YKT6 p190ARHOGAP
Initiation of Nuclear Envelope (NE) Reformation	Ankyrin repeat and LEM domain-containing protein 2 Barrier-to-autointegration factor Cyclin-dependent kinase 1 Delta(14)-sterol reductase LBR Emerin G2/mitotic-specific cyclin-B1 G2/mitotic-specific cyclin-B2 Importin subunit beta-1 Inner nuclear membrane protein Man1 LEM domain-containing protein 2 Lamin-B1 NAD-dependent protein deacetylase sirtuin-2 Serine/threonine-protein kinase VRK1 Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform	O75531 O95067 P06493 P14635 P20700 P30153 P50402 P63151 P67775 Q14739 Q14974 Q86XL3 Q8IXJ6 Q8NC56 Q99986 Q9Y2U8	ANKLE2 BAF BANF1 BCRG1 CCNB CCNB1 CCNB2 CDC2 CDC28A CDK1 CDKN1 EDMD EMD KIAA0692 KPNB1 LBR LEM4 LEMD2 LEMD3 LMN2 LMNB LMNB1 MAN1 NTF97 P34CDC2 PPP2CA PPP2R1A PPP2R2A SIR2L SIR2L2 SIRT2 STA VRK1
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB	Bridging integrator 2 Golgin subfamily A member 4 KN motif and ankyrin repeat domain-containing protein 1 Transcription factor ETV6 Vascular endothelial growth factor receptor 2	P35968 P41212 Q13439 Q14678 Q9UBW5	ANKRD15 BIN2 BRAP1 ETV6 FLK1 GOLGA4 KANK KANK1 KDR KIAA0172 TEL TEL1 VEGFR2
RND3 GTPase cycle	Ankyrin repeat domain-containing protein 26 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 Carboxypeptidase D Caveolin-1 Creatine kinase B-type Cytoskeleton-associated protein 4 DEP domain-containing protein 1B Desmoglein-1 Desmoplakin Disks large homolog 5 Dystonin Ephrin type-A receptor 2 Flotillin-2 Girdin Inner nuclear membrane protein Man1 Kinectin Mucin-13 Nischarin Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol-binding clathrin assembly protein Plakophilin-4 Pleckstrin homology domain-containing family G member 5 Probable ATP-dependent RNA helicase DDX4 Protein FAM83B Protein scribble homolog RNA-binding motif protein, X chromosome Ras GTPase-activating protein nGAP Rho GTPase-activating protein 21 Rho GTPase-activating protein 35 Rho GTPase-activating protein 5 Rho-associated protein kinase 1 Rho-related GTP-binding protein RhoE Semaphorin-4F Thioredoxin-like protein 1 Tropomodulin-3 Tyrosine-protein phosphatase non-receptor type 13 UBX domain-containing protein 11 Vang-like protein 1 Vang-like protein 2 tRNA (34-2'-O)-methyltransferase regulator WDR6	O00459 O43396 O75976 O94827 O95754 P12277 P15924 P27986 P29317 P38159 P61587 Q02413 Q03001 Q03135 Q07065 Q12923 Q13017 Q13464 Q13492 Q13829 Q14160 Q14254 Q3V6T2 Q5T0W9 Q5T124 Q5T5U3 Q86UP2 Q8TAA9 Q8TDM6 Q8WUY9 Q8WZ19 Q99569 Q9H3R2 Q9NNW5 Q9NQI0 Q9NRY4 Q9NYL9 Q9UJF2 Q9ULK5 Q9UPS8 Q9Y2I1 Q9Y2U8	ANKRD26 APE ARHE ARHGAP10 ARHGAP21 ARHGAP35 ARHGAP5 BACURD1 BACURD2 BP230 BP240 BPAG1 C6orf143 CALM CAV CAV1 CCDC88A CDHF4 CG1 CKAP4 CKB CKBB CPD CRIB1 DDX4 DEPDC1B DLG5 DMH DRCC1 DSG1 DSP DST DT ECK EDP1 EPHA2 ESA1 FAM83B FLOT2 GRB1 GRDN GRF1 GRLF1 HNRPG IRAS KCTD13 KIAA0004 KIAA0147 KIAA0583 KIAA0720 KIAA0728 KIAA0975 KIAA1074 KIAA1212 KIAA1215 KIAA1424 KIAA1722 KTN1 LAP4 LEMD3 M17S1 MAN1 MUC13 NGAP NISCH P190A PDIP1 PDLG PICALM PIK3R1 PIK3R2 PKP4 PLEKHG5 PNP1 POLDIP1 PTP1E PTPL1 PTPN13 RASAL2 RBMX RBMXP1 RECC RHO8 RHOE RHOGAP5 RND3 ROCK1 SCRB1 SCRIB SEMA4F SEMAM SEMAW SOC STB1 STB2 TMOD3 TNFAIP1 TRP32 TXL TXNL TXNL1 UBXD5 UBXN11 VANGL1 VANGL2 VARTUL VASA WDR6 XTP8 p190ARHOGAP
TRP channels	Mucolipin-1 Mucolipin-2 Mucolipin-3 Short transient receptor potential channel 1 Short transient receptor potential channel 3 Short transient receptor potential channel 4-associated protein Short transient receptor potential channel 4 Short transient receptor potential channel 5 Short transient receptor potential channel 6 Short transient receptor potential channel 7 Transient receptor potential cation channel subfamily A member 1 Transient receptor potential cation channel subfamily M member 1 Transient receptor potential cation channel subfamily M member 2 Transient receptor potential cation channel subfamily M member 3 Transient receptor potential cation channel subfamily M member 4 Transient receptor potential cation channel subfamily M member 5 Transient receptor potential cation channel subfamily M member 6 Transient receptor potential cation channel subfamily M member 7 Transient receptor potential cation channel subfamily M member 8 Transient receptor potential cation channel subfamily V member 1 Transient receptor potential cation channel subfamily V member 2 Transient receptor potential cation channel subfamily V member 3 Transient receptor potential cation channel subfamily V member 4 Transient receptor potential cation channel subfamily V member 5 Transient receptor potential cation channel subfamily V member 6	O75762 O94759 P48995 Q13507 Q7Z2W7 Q7Z4N2 Q8IZK6 Q8NER1 Q8NET8 Q8TD43 Q8TDD5 Q8TEL6 Q96QT4 Q9BX84 Q9GZU1 Q9H1D0 Q9HBA0 Q9HCF6 Q9HCX4 Q9NQA5 Q9NZQ8 Q9UBN4 Q9UL62 Q9Y210 Q9Y5S1	ANKTM1 C20orf188 CHAK1 CHAK2 ECAC1 ECAC2 EREG1 KIAA1616 KNP3 LTRPC1 LTRPC2 LTRPC3 LTRPC4 LTRPC5 LTRPC6 LTRPC7 MCOLN1 MCOLN2 MCOLN3 ML4 MLSN MLSN1 MTR1 TRP1 TRP3 TRP5 TRP6 TRP7 TRPA1 TRPC1 TRPC3 TRPC4 TRPC4AP TRPC5 TRPC6 TRPC7 TRPM1 TRPM2 TRPM3 TRPM4 TRPM5 TRPM6 TRPM7 TRPM8 TRPML1 TRPP8 TRPV1 TRPV2 TRPV3 TRPV4 TRPV5 TRPV6 TRRP4AP VR1 VRL VRL2 VROAC
Physiological factors	Atrial natriuretic peptide receptor 1 Atrial natriuretic peptide receptor 2 Atrial natriuretic peptide-converting enzyme C-type natriuretic peptide Histone acetyltransferase KAT2B Homeobox protein Nkx-2.5 Homeodomain-interacting protein kinase 1 Homeodomain-interacting protein kinase 2 Liver carboxylesterase 1 Natriuretic peptides A Neprilysin T-box transcription factor TBX5 Transcription factor GATA-4 WW domain-containing transcription regulator protein 1	P01160 P08473 P16066 P20594 P23141 P23582 P43694 P52952 Q86Z02 Q92831 Q99593 Q9GZV5 Q9H2X6 Q9Y5Q5	ANP ANPRA ANPRB CES1 CES2 CNP2 CORIN CRN CSX EPN GATA4 HIPK1 HIPK2 KAT2B KIAA0630 MME MYAK NBAK2 NKX2-5 NKX2.5 NKX2E NPPA NPPC NPR1 NPR2 PCAF PND SES1 TAZ TBX5 TMPRSS10 WWTR1
YAP1- and WWTR1 (TAZ)-stimulated gene expression	CCN family member 2 Histone acetyltransferase KAT2B Homeobox protein Nkx-2.5 Homeodomain-interacting protein kinase 1 Homeodomain-interacting protein kinase 2 Natriuretic peptides A T-box transcription factor TBX5 Transcription factor GATA-4 Transcriptional coactivator YAP1 Transcriptional enhancer factor TEF-1 Transcriptional enhancer factor TEF-3 Transcriptional enhancer factor TEF-4 Transcriptional enhancer factor TEF-5 WW domain-containing transcription regulator protein 1	P01160 P28347 P29279 P43694 P46937 P52952 Q15561 Q15562 Q86Z02 Q92831 Q99593 Q99594 Q9GZV5 Q9H2X6	ANP CCN2 CSX CTGF GATA4 HCS24 HIPK1 HIPK2 IGFBP8 KAT2B KIAA0630 MYAK NBAK2 NKX2-5 NKX2.5 NKX2E NPPA PCAF PND RTEF1 TAZ TBX5 TCF13 TCF13L1 TEAD1 TEAD2 TEAD3 TEAD4 TEAD5 TEF1 TEF3 TEF4 TEF5 WWTR1 YAP1 YAP65
HuR (ELAVL1) binds and stabilizes mRNA	Acidic leucine-rich nuclear phosphoprotein 32 family member A ELAV-like protein 1 Exportin-1 Nuclear pore complex protein Nup214 Protein SET Protein kinase C alpha type Protein kinase C delta type Tumor necrosis factor ligand superfamily member 13	O14980 O75888 P17252 P35658 P39687 Q01105 Q05655 Q15717	ANP32A APRIL C15orf1 CAIN CAN CRM1 ELAVL1 HUR KIAA0023 LANP MAPM NUP214 PHAP1 PKCA PKCD PRKACA PRKCA PRKCD SET TALL2 TNFSF13 XPO1 ZTNF2
Vitamin B6 activation to pyridoxal phosphate	Aldehyde oxidase Pyridoxal kinase Pyridoxine-5'-phosphate oxidase	O00764 Q06278 Q9NVS9	AO AOX1 C21orf124 C21orf97 PDXK PKH PNK PNPO
HDMs demethylate histones	AT-rich interactive domain-containing protein 5B Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 Histone H3.1 Histone H3.2 Histone H4 Histone demethylase UTY Histone lysine demethylase PHF8 Lysine-specific demethylase 2A Lysine-specific demethylase 2B Lysine-specific demethylase 3A Lysine-specific demethylase 3B Lysine-specific demethylase 4A Lysine-specific demethylase 4B Lysine-specific demethylase 4C Lysine-specific demethylase 4D Lysine-specific demethylase 5A Lysine-specific demethylase 5B Lysine-specific demethylase 5C Lysine-specific demethylase 5D Lysine-specific demethylase 6A Lysine-specific demethylase 6B Lysine-specific demethylase 7A Lysine-specific demethylase PHF2 Lysine-specific histone demethylase 1A Lysine-specific histone demethylase 2 Ribosomal oxygenase 2	O14607 O15054 O15550 O60341 O75151 O75164 O94953 P29375 P41229 P62805 P68431 Q14865 Q6B0I6 Q6NYC1 Q6ZMT4 Q71DI3 Q7LBC6 Q8IUF8 Q8NB78 Q8NHM5 Q9BY66 Q9H3R0 Q9UGL1 Q9UPP1 Q9Y2K7 Q9Y4C1	AOF1 AOF2 ARID5B C5orf7 C6orf193 CENP-35 CXXC2 CXXC8 DESRT DXS1272E FBL10 FBL11 FBL7 FBXL10 FBXL11 GASC1 H3C1 H3C10 H3C11 H3C12 H3C13 H3C14 H3C15 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 H3F2 H3FA H3FB H3FC HIST1H3C H3FD H3FF H3FH H3FI H3FJ H3FK H3FL H3FM H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HIST1H3A HIST1H3B HIST1H3D HIST1H3E HIST1H3F HIST1H3G HIST1H3H HIST1H3I HIST1H3J HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H3A HIST2H3C HIST2H3D HIST2H4 HIST2H4A HIST2H4B HIST4H4 HY HYA JARID1A JARID1B JARID1C JARID1D JHDM1A JHDM1B JHDM1D JHDM2A JHDM2B JHDM3A JHDM3B JHDM3C JHDM3D JMJD1 JMJD1A JMJD1B JMJD2 JMJD2A JMJD2B JMJD2C JMJD2D JMJD3 JMJD6 KDM1 KDM1A KDM1B KDM2A KDM2B KDM3A KDM3B KDM4A KDM4B KDM4C KDM4D KDM5A KDM5B KDM5C KDM5D KDM6A KDM6B KDM6C KDM7 KDM7A KIAA0234 KIAA0346 KIAA0585 KIAA0601 KIAA0662 KIAA0677 KIAA0742 KIAA0780 KIAA0876 KIAA1004 KIAA1082 KIAA1111 KIAA1718 LSD1 LSD2 MDIG MINA MINA53 MRF2 NDY1 NO52 PCCX2 PHF2 PHF8 PLU1 PSR PTDSR RBBP2 RBBP2H1 RBP2 RIOX2 SMCX SMCY TSGA UTX UTY XE169 ZNF422
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3	Androgen receptor Histone H2A type 1-B/E Histone H2A type 1-C Histone H2A type 1-D Histone H2A type 1-J Histone H2A type 2-A Histone H2A type 2-C Histone H2A-Bbd type 1 Histone H2A.J Histone H2A.V Histone H2AX Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/F/G/I Histone H2B type 1-D Histone H2B type 1-H Histone H2B type 1-J Histone H2B type 1-K Histone H2B type 1-L Histone H2B type 1-M Histone H2B type 1-N Histone H2B type 1-O Histone H2B type 2-E Histone H2B type 3-B Histone H2B type F-S Histone H3.1 Histone H3.2 Histone H3.3 Histone H4 Kallikrein-2 Lysine-specific demethylase 4C Lysine-specific histone demethylase 1A Nuclear receptor coactivator 2 Prostate-specific antigen Serine/threonine-protein kinase N1	O60341 O60814 P04908 P06899 P07288 P0C5Y9 P10275 P16104 P20151 P20671 P23527 P33778 P57053 P58876 P62805 P62807 P68431 P84243 Q15596 Q16512 Q16777 Q16778 Q6FI13 Q71DI3 Q71UI9 Q8N257 Q93077 Q93079 Q96A08 Q99877 Q99878 Q99879 Q99880 Q9BTM1 Q9H3R0	AOF2 APS AR BHLHE75 DHTR GASC1 H2AB1 H2AC14 H2AC18 H2AC19 H2AC20 H2AC4 H2AC6 H2AC7 H2AC8 H2AFA H2AFB1 H2AFE H2AFG H2AFJ H2AFL H2AFM H2AFO H2AFQ H2AFV H2AFX H2AJ H2AV H2AX H2AZ2 H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H2BFA H2BFB H2BFC H2BFD H2BFE H2BFF H2BFG H2BFH H2BFJ H2BFK H2BFL H2BFN H2BFQ H2BFR H2BFS H2BFT H2BS1 H2BU1 H3-3A H3-3B H3.3A H3.3B H3C1 H3C10 H3C11 H3C12 H3C13 H3C14 H3C15 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 H3F2 H3F3 H3F3A H3F3B H3FA H3FB H3FC HIST1H3C H3FD H3FF H3FH H3FI H3FJ H3FK H3FL H3FM H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HIRIP1 HIRIP2 HIST1H2AB HIST1H2AC HIST1H2AD HIST1H2AE HIST1H2AJ HIST1H2BA HIST1H2BB HIST1H2BC HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2BI HIST1H2BJ HIST1H2BK HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST1H3A HIST1H3B HIST1H3D HIST1H3E HIST1H3F HIST1H3G HIST1H3H HIST1H3I HIST1H3J HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H2AA HIST2H2AA3 HIST2H2AA4 HIST2H2AC HIST2H2BE HIST2H3A HIST2H3C HIST2H3D HIST2H4 HIST2H4A HIST2H4B HIST3H2BB HIST4H4 JHDM3C JMJD2C KDM1 KDM1A KDM4C KIAA0601 KIAA0780 KLK2 KLK3 LSD1 NCOA2 NR3C4 PAK1 PKN PKN1 PRK1 PRKCL1 SRC2 TIF2 TSH2B
HDACs deacetylate histones	AT-rich interactive domain-containing protein 4A AT-rich interactive domain-containing protein 4B Breast cancer metastasis-suppressor 1 Chromodomain-helicase-DNA-binding protein 3 Chromodomain-helicase-DNA-binding protein 4 F-box-like/WD repeat-containing protein TBL1X F-box-like/WD repeat-containing protein TBL1XR1 G protein pathway suppressor 2 Histone H2A type 1-A Histone H2A type 1-B/E Histone H2A type 1-C Histone H2A type 1-D Histone H2A type 1-H Histone H2A type 1-J Histone H2A type 1 Histone H2A type 2-A Histone H2A type 2-B Histone H2A type 2-C Histone H2A type 3 Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/F/G/I Histone H2B type 1-D Histone H2B type 1-H Histone H2B type 1-J Histone H2B type 1-K Histone H2B type 1-L Histone H2B type 1-M Histone H2B type 1-N Histone H2B type 1-O Histone H2B type 2-E Histone H2B type 2-F Histone H2B type 3-B Histone H3.1 Histone H3.2 Histone H4 Histone deacetylase 1 Histone deacetylase 2 Histone deacetylase 3 Histone deacetylase 8 Histone deacetylase complex subunit SAP18 Histone deacetylase complex subunit SAP30 Histone deacetylase complex subunit SAP30L Histone-binding protein RBBP4 Histone-binding protein RBBP7 Lysine-specific histone demethylase 1A Metastasis-associated protein MTA1 Metastasis-associated protein MTA2 Metastasis-associated protein MTA3 Methyl-CpG-binding domain protein 3 Nuclear receptor corepressor 1 Nuclear receptor corepressor 2 PHD finger protein 21A Polyamine deacetylase HDAC10 RE1-silencing transcription factor REST corepressor 1 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related Sin3 histone deacetylase corepressor complex component SDS3 Transcriptional repressor p66-alpha Transcriptional repressor p66-beta	O00422 O15379 O60341 O60814 O60907 O75376 O75446 O94776 O95983 P04908 P06899 P0C0S8 P20671 P23527 P29374 P33778 P58876 P62805 P62807 P68431 Q09028 Q12873 Q13127 Q13227 Q13330 Q13547 Q14839 Q16576 Q16777 Q16778 Q4LE39 Q5QNW6 Q6FI13 Q71DI3 Q7L7L0 Q86YP4 Q8IUE6 Q8N257 Q8WXI9 Q92769 Q93077 Q93079 Q969S8 Q96A08 Q96BD5 Q96KK5 Q96QV6 Q99877 Q99878 Q99879 Q99880 Q9BTC8 Q9BY41 Q9BZK7 Q9H7L9 Q9HAJ7 Q9HCU9 Q9P0W2 Q9UKL0 Q9Y618	AOF2 ARID4A ARID4B BHC80 BRAF35 BRCAA1 BRMS1 CHD3 CHD4 CTG26 GATAD2A GATAD2B GPS2 H2AC1 H2AC11 H2AC12 H2AC13 H2AC14 H2AC15 H2AC16 H2AC17 H2AC18 H2AC19 H2AC20 H2AC21 H2AC25 H2AC4 H2AC6 H2AC7 H2AC8 H2AFA H2AFC H2AFD H2AFE H2AFG H2AFI H2AFL H2AFM H2AFN H2AFO H2AFP H2AFQ H2AFR H2AW H2BC1 H2BC10 H2BC11 H2BC12 H2BC13 H2BC14 H2BC15 H2BC17 H2BC18 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H2BFA H2BFB H2BFC H2BFD H2BFE H2BFF H2BFG H2BFH H2BFJ H2BFK H2BFL H2BFN H2BFQ H2BFR H2BFT H2BU1 H3C1 H3C10 H3C11 H3C12 H3C13 H3C14 H3C15 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 H3F2 H3FA H3FB H3FC HIST1H3C H3FD H3FF H3FH H3FI H3FJ H3FK H3FL H3FM H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HDAC1 HDAC10 HDAC2 HDAC3 HDAC8 HDACL1 HIRIP1 HIRIP2 HIST1H2AA HIST1H2AB HIST1H2AC HIST1H2AD HIST1H2AE HIST1H2AG HIST1H2AH HIST1H2AI HIST1H2AJ HIST1H2AK HIST1H2AL HIST1H2AM HIST1H2BA HIST1H2BB HIST1H2BC HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2BI HIST1H2BJ HIST1H2BK HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST1H3A HIST1H3B HIST1H3D HIST1H3E HIST1H3F HIST1H3G HIST1H3H HIST1H3I HIST1H3J HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H2AA HIST2H2AA3 HIST2H2AA4 HIST2H2AB HIST2H2AC HIST2H2BE HIST2H2BF HIST2H3A HIST2H3C HIST2H3D HIST2H4 HIST2H4A HIST2H4B HIST3H2A HIST3H2BB HIST4H4 HMG20B HMGX2 HMGXB2 IRA1 KDM1 KDM1A KIAA0071 KIAA0601 KIAA1047 KIAA1150 KIAA1266 KIAA1696 LSD1 MBD3 MTA1 MTA1L1 MTA2 MTA3 NCOR1 NCOR2 NRSF NS4ATP2 PHF21A PID RBAP46 RBAP48 RBBP1 RBBP1L1 RBBP4 RBBP7 RBP1 RBP1L1 RCOR RCOR1 REST RPD3L1 SAP18 SAP180 SAP30 SAP30L SAP45 SDS3 SMARCE1R SUDS3 TBL1 TBL1X TBL1XR1 TBLR1 TSH2B XBR
Regulation of PTEN gene transcription	Atrophin-1 Cellular tumor antigen p53 Chromobox protein homolog 2 Chromobox protein homolog 6 Chromobox protein homolog 8 Chromodomain-helicase-DNA-binding protein 3 Chromodomain-helicase-DNA-binding protein 4 Cyclic AMP-dependent transcription factor ATF-2 E3 SUMO-protein ligase CBX4 E3 ubiquitin-protein ligase RING1 E3 ubiquitin-protein ligase RING2 Early growth response protein 1 GTP-binding protein Rheb Histone deacetylase 1 Histone deacetylase 2 Histone deacetylase 3 Histone deacetylase 5 Histone deacetylase 7 Histone-binding protein RBBP4 Histone-binding protein RBBP7 Histone-lysine N-methyltransferase EZH2 Histone-lysine N-methyltransferase MECOM Lysine-specific histone demethylase 1A Metastasis-associated protein MTA1 Metastasis-associated protein MTA2 Metastasis-associated protein MTA3 Methyl-CpG-binding domain protein 3 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Neutral amino acid transporter 9 Nuclear receptor subfamily 2 group E member 1 Peroxisome proliferator-activated receptor gamma Polycomb complex protein BMI-1 Polycomb protein EED Polycomb protein SUZ12 Polyhomeotic-like protein 1 Polyhomeotic-like protein 2 Polyhomeotic-like protein 3 RE1-silencing transcription factor REST corepressor 1 Ragulator complex protein LAMTOR1 Ragulator complex protein LAMTOR2 Ragulator complex protein LAMTOR3 Ragulator complex protein LAMTOR4 Ragulator complex protein LAMTOR5 Ras-related GTP-binding protein A Ras-related GTP-binding protein B Ras-related GTP-binding protein C Ras-related GTP-binding protein D Regulatory-associated protein of mTOR Repressor of RNA polymerase III transcription MAF1 homolog Sal-like protein 4 Serine/threonine-protein kinase mTOR Target of rapamycin complex subunit LST8 Transcription factor Jun Transcriptional repressor p66-alpha Transcriptional repressor p66-beta Zinc finger protein SNAI1 Zinc finger protein SNAI2	O00257 O15379 O43504 O43623 O60341 O75530 O94776 O95503 O95863 O95983 P04637 P05412 P15336 P18146 P27361 P28482 P35226 P37231 P42345 P54259 P78364 Q03112 Q06587 Q09028 Q0VGL1 Q12873 Q13127 Q13330 Q13547 Q14781 Q14839 Q15022 Q15382 Q15910 Q16576 Q5VZM2 Q6IAA8 Q7L523 Q86YP4 Q8IXK0 Q8N122 Q8NBW4 Q8NDX5 Q8WUI4 Q8WXI9 Q92769 Q99496 Q9BTC8 Q9BVC4 Q9H063 Q9HB90 Q9HC52 Q9NQL2 Q9UHA4 Q9UJQ4 Q9UKL0 Q9UQL6 Q9Y2Q5 Q9Y466	AOF2 ATF2 ATN1 BAP1 BMI1 C11orf59 C7orf59 CBX2 CBX4 CBX6 CBX8 CHD3 CHD4 CHET9 CREB2 CREBP1 D12S755E DING DRPLA EDR1 EDR2 EDR3 EED EGR1 ERK1 ERK2 EVI1 EZH2 FRAP FRAP1 FRAP2 GATAD2A GATAD2B GBL HBXIP HDAC1 HDAC2 HDAC3 HDAC5 HDAC7 HDAC7A HIPI3 JJAZ1 JUN KDM1 KDM1A KIAA0071 KIAA0160 KIAA0600 KIAA0601 KIAA1150 KIAA1266 KIAA1303 KMT6 KROX24 LAMTOR1 LAMTOR2 LAMTOR3 LAMTOR4 LAMTOR5 LSD1 LST8 MAF1 MAP2K1IP1 MAPBPIP MAPK1 MAPK3 MAPKSP1 MBD3 MDS1 MECOM MLST8 MTA1 MTA1L1 MTA2 MTA3 MTOR NR1C3 NR2E1 NRSF P53 PC3 PCGF4 PDRO PH1 PH2 PH3 PHC1 PHC2 PHC3 PID PPARG PRDM3 PRKM1 PRKM2 PRKM3 RAFT1 RAPT1 RAPTOR RBAP46 RBAP48 RBBP4 RBBP7 RC1 RCOR RCOR1 REST RHEB RHEB2 RING1 RING1A RING1B RNF1 RNF2 RNF51 ROBLD3 RPD3L1 RPTOR RRAGA RRAGB RRAGC RRAGD SALL4 SLC38A9 SLUG SLUGH SNAH SNAI1 SNAI2 SUZ12 TLX TP53 URLC11 XBR XIP ZNF225 ZNF797
Detoxification of Reactive Oxygen Species	Aquaporin-8 Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] Catalase Copper chaperone for superoxide dismutase Copper transport protein ATOX1 Copper-transporting ATPase 1 Cytochrome b-245 heavy chain Cytochrome b-245 light chain Cytochrome c ERO1-like protein alpha Epididymal secretory glutathione peroxidase Extracellular superoxide dismutase [Cu-Zn] Glutathione S-transferase P Glutathione peroxidase 1 Glutathione peroxidase 2 Glutathione peroxidase 3 Glutathione peroxidase 6 Glutathione peroxidase 7 NADPH oxidase 4 NADPH oxidase 5 Neutrophil cytosol factor 1 Neutrophil cytosol factor 2 Neutrophil cytosol factor 4 Peroxiredoxin-1 Peroxiredoxin-2 Peroxiredoxin-6 Probable glutathione peroxidase 8 Protein disulfide-isomerase Superoxide dismutase [Cu-Zn] Superoxide dismutase [Mn], mitochondrial Thioredoxin reductase 1, cytoplasmic Thioredoxin reductase 2, mitochondrial Thioredoxin, mitochondrial Thioredoxin-dependent peroxide reductase, mitochondrial Thioredoxin	O00244 O14618 O75715 O94778 P00441 P04040 P04179 P04839 P07203 P07237 P08294 P09211 P10599 P13498 P14598 P18283 P19878 P22352 P30041 P30048 P32119 P50583 P59796 P99999 Q04656 Q06830 Q15080 Q16881 Q8TED1 Q96HE7 Q96PH1 Q96SL4 Q99757 Q9NNW7 Q9NPH5	AOP1 AOP2 APAH1 AQP8 ATOX1 ATP7A CAT CCS CYBA CYBB CYC CYCS ERBA2L ERO1A ERO1L FAEES3 GPX1 GPX2 GPX3 GPX5 GPX6 GPX7 GPX8 GPXP GRIM12 GST3 GSTP1 HAH1 KDRF KIAA0106 KIAA1652 MC1 MNK NCF1 NCF2 NCF4 NKEFB NOX2 NOX4 NOX5 NOXA2 NOXO2 NUDT2 P4HB P67PHOX PAGA PAGB PDI PDIA1 PO4DB PRDX1 PRDX2 PRDX3 PRDX6 RENOX SH3PXD1A SH3PXD4 SOD1 SOD2 SOD3 TDPX1 TDPX2 TRDX TRX TRX1 TRX2 TRXR2 TXN TXN2 TXNRD1 TXNRD2
SUMO is transferred from E1 to E2 (UBE2I, UBC9)	RWD domain-containing protein 3 SUMO-activating enzyme subunit 1 SUMO-activating enzyme subunit 2 SUMO-conjugating enzyme UBC9 Small ubiquitin-related modifier 1 Small ubiquitin-related modifier 2 Small ubiquitin-related modifier 3	P55854 P61956 P63165 P63279 Q9UBE0 Q9UBT2 Q9Y3V2	AOS1 RSUME RWDD3 SAE1 SAE2 SMT3A SMT3B SMT3C SMT3H1 SMT3H2 SMT3H3 SUA1 SUMO1 SUMO2 SUMO3 UBA2 UBC9 UBCE9 UBE2I UBL1 UBLE1A UBLE1B
SUMO is conjugated to E1 (UBA2:SAE1)	SUMO-activating enzyme subunit 1 SUMO-activating enzyme subunit 2 Small ubiquitin-related modifier 1 Small ubiquitin-related modifier 2 Small ubiquitin-related modifier 3	P55854 P61956 P63165 Q9UBE0 Q9UBT2	AOS1 SAE1 SAE2 SMT3A SMT3B SMT3C SMT3H1 SMT3H2 SMT3H3 SUA1 SUMO1 SUMO2 SUMO3 UBA2 UBL1 UBLE1A UBLE1B
Nef mediated downregulation of CD28 cell surface expression	AP-2 complex subunit mu Protein Nef T-cell-specific surface glycoprotein CD28	P04601 P10747 Q96CW1	AP2M1 CD28 CLAPM1 KIAA0109 nef

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