GlyCosmos Portal

Homo sapiens (human)

Summary

Taxonomy ID: 9606
PubChem Taxonomy: 9606

Genes (1582) Glycans (5831) Glycoproteins (18496) Lectins (298) Pathways (2090)

Displaying entries **826 - 850** of **2090** in total

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Pathway Name	Protein Name ▲	UniProt ID	Gene Symbol
Release of apoptotic factors from the mitochondria	Apoptosis regulator BAX Bcl-2 homologous antagonist/killer Cytochrome c Diablo IAP-binding mitochondrial protein Gasdermin-D Gasdermin-E	O60443 P57764 P99999 Q07812 Q16611 Q9NR28	BAK BAK1 BAX BCL2L4 BCL2L7 CDN1 CYC CYCS DFNA5 DFNA5L DIABLO GSDMD GSDMDC1 GSDME ICERE1 SMAC
Transcriptional regulation by RUNX2	Apoptosis regulator BAX Bone morphogenetic protein 2 Core-binding factor subunit beta Cyclin-dependent kinase 1 Cyclin-dependent kinase 4 Cyclin-dependent kinase inhibitor 1 G1/S-specific cyclin-D1 G2/mitotic-specific cyclin-B1 Heart- and neural crest derivatives-expressed protein 2 Histone deacetylase 6 Protein phosphatase 1D Transcription factor SOX-9 Twist-related protein 1 Twist-related protein 2	O15297 P06493 P11802 P12643 P14635 P24385 P38936 P48436 P61296 Q07812 Q13951 Q15672 Q8WVJ9 Q9UBN7	BAX BCL1 BCL2L4 BHLHA26 BHLHA38 BHLHA39 BMP2 BMP2A CAP20 CBFB CCNB CCNB1 CCND1 CDC2 CDC28A CDK1 CDK4 CDKN1 CDKN1A CIP1 DERMO1 DHAND HAND2 HDAC6 KIAA0901 MDA6 P34CDC2 PIC1 PPM1D PRAD1 SDI1 SOX9 TWIST TWIST1 TWIST2 WAF1 WIP1
NTRK3 as a dependence receptor	Apoptosis regulator BAX NT-3 growth factor receptor Negative elongation factor B	Q07812 Q16288 Q8WX92	BAX BCL2L4 COBRA1 KIAA1182 NELFB NTRK3 TRKC
Estrogen-dependent gene expression	Apoptosis regulator Bcl-2 Axin-1 BTB/POZ domain-containing protein KCTD6 CREB-binding protein CXXC-type zinc finger protein 5 Cathepsin D Cbp/p300-interacting transactivator 1 Chromodomain-helicase-DNA-binding protein 1 Cohesin subunit SA-1 Cohesin subunit SA-2 Core-binding factor subunit beta Cyclic AMP-dependent transcription factor ATF-2 Cyclin-T1 Cyclin-dependent kinase 9 DNA-directed RNA polymerase II subunit RPB11-a DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 Double-strand-break repair protein rad21 homolog Estrogen receptor G1/S-specific cyclin-D1 General transcription factor IIF subunit 1 General transcription factor IIF subunit 2 Glycerol-3-phosphate acyltransferase 1, mitochondrial Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Helicase MOV-10 Hepatocyte nuclear factor 3-alpha Histone H2A type 1-B/E Histone H2A type 1-C Histone H2A type 1-D Histone H2A type 1-J Histone H2A type 2-A Histone H2A type 2-C Histone H2A-Bbd type 1 Histone H2A.J Histone H2A.V Histone H2AX Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/F/G/I Histone H2B type 1-D Histone H2B type 1-H Histone H2B type 1-J Histone H2B type 1-K Histone H2B type 1-L Histone H2B type 1-M Histone H2B type 1-N Histone H2B type 1-O Histone H2B type 2-E Histone H2B type 3-B Histone H2B type F-S Histone H3.1 Histone H3.2 Histone H3.3 Histone H4 Histone acetyltransferase KAT2B Histone acetyltransferase KAT5 Histone acetyltransferase p300 Histone deacetylase 1 Histone-arginine methyltransferase CARM1 Importin subunit alpha-1 KN motif and ankyrin repeat domain-containing protein 1 Lysine-specific demethylase 4B Lysine-specific histone demethylase 1A Mediator of RNA polymerase II transcription subunit 1 Myc proto-oncogene protein Nuclear receptor coactivator 1 Nuclear receptor coactivator 2 Nuclear receptor coactivator 3 Nuclear receptor subfamily 5 group A member 2 Nuclear receptor-interacting protein 1 POU domain, class 2, transcription factor 1 Peptidyl-prolyl cis-trans isomerase FKBP4 Probable ATP-dependent RNA helicase DDX5 Progesterone receptor Prostaglandin E synthase 3 Protein FosB Protein GREB1 Protein arginine N-methyltransferase 1 Protein argonaute-1 Protein argonaute-2 Protein argonaute-3 Protein argonaute-4 Protein c-Fos Protransforming growth factor alpha Receptor-binding cancer antigen expressed on SiSo cells Runt-related transcription factor 1 Stromal cell-derived factor 1 Structural maintenance of chromosomes protein 1A Structural maintenance of chromosomes protein 3 TATA-box-binding protein Trans-acting T-cell-specific transcription factor GATA-3 Transcription factor Jun Transcription factor JunD Transcription factor Sp1 Transcription initiation factor IIA subunit 1 Transcription initiation factor IIA subunit 2 Transcriptional activator Myb Transcriptional repressor protein YY1 Transducin-like enhancer protein 3 Trefoil factor 1 Trefoil factor 3 Trinucleotide repeat-containing gene 6A protein Trinucleotide repeat-containing gene 6B protein Trinucleotide repeat-containing gene 6C protein Upstream stimulatory factor 1 Upstream stimulatory factor 2 Zinc finger protein 217	O00482 O00559 O14646 O15169 O15514 O60216 O60341 O60563 O60814 O75362 O94953 P01100 P01106 P01135 P03372 P04155 P04908 P05412 P06401 P06899 P07339 P07900 P08047 P08238 P0C5Y9 P10242 P10415 P13984 P14859 P15336 P16104 P17535 P17844 P19387 P19388 P20226 P20671 P22415 P23527 P23771 P24385 P24928 P25490 P30876 P33778 P35269 P36954 P48061 P48552 P50750 P52292 P52434 P52435 P52655 P52657 P53539 P53803 P55317 P57053 P58876 P61218 P62487 P62805 P62807 P62875 P68431 P84243 Q01196 Q02790 Q04726 Q07654 Q09472 Q13547 Q13951 Q14678 Q14683 Q15185 Q15596 Q15648 Q15788 Q15853 Q16777 Q16778 Q4ZG55 Q6FI13 Q71DI3 Q71UI9 Q7LFL8 Q86X55 Q8N257 Q8N3U4 Q8NC69 Q8NDV7 Q8WVM7 Q92793 Q92831 Q92993 Q93077 Q93079 Q96A08 Q99873 Q99877 Q99878 Q99879 Q99880 Q99966 Q9BTM1 Q9H9G7 Q9HCE1 Q9HCJ0 Q9HCK5 Q9HCL2 Q9UKV8 Q9UL18 Q9UPQ9 Q9UQE7 Q9Y6Q9	AGO1 AGO2 AGO3 AGO4 AIB1 AML1 ANKRD15 AOF2 ARC205 ATF2 AXIN AXIN1 B1F BAM BCEI BCL1 BCL2 BHLHB11 BHLHB12 BHLHE39 BHLHE42 BHLHE74 BHLHE75 BMH CAGH26 CARM1 CBFA2 CBFB CBP CCND1 CCNT1 CDC2L4 CDK9 CHD1 CITED1 CPF CPSD CREB2 CREBBP CREBP1 CRSP1 CRSP200 CSPG6 CTSD CXCL12 CXXC5 DDX5 DRIP205 DRIP230 DXS423E EBAG9 EIF2C1 EIF2C2 EIF2C3 EIF2C4 EP300 ESR ESR1 FKBP4 FKBP52 FOS FOSB FOXA1 FTF G0S3 G0S7 G17P1 GATA3 GPAM GPAT1 GREB1 GTF2A1 GTF2A2 GTF2D1 GTF2F1 GTF2F2 H2AB1 H2AC14 H2AC18 H2AC19 H2AC20 H2AC4 H2AC6 H2AC7 H2AC8 H2AFA H2AFB1 H2AFE H2AFG H2AFJ H2AFL H2AFM H2AFO H2AFQ H2AFV H2AFX H2AJ H2AV H2AX H2AZ2 H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H2BFA H2BFB H2BFC H2BFD H2BFE H2BFF H2BFG H2BFH H2BFJ H2BFK H2BFL H2BFN H2BFQ H2BFR H2BFS H2BFT H2BS1 H2BU1 H3-3A H3-3B H3.3A H3.3B H3C1 H3C10 H3C11 H3C12 H3C13 H3C14 H3C15 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 H3F2 H3F3 H3F3A H3F3B H3FA H3FB H3FC HIST1H3C H3FD H3FF H3FH H3FI H3FJ H3FK H3FL H3FM H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HDAC1 HELR HIRIP1 HIRIP2 HIST1H2AB HIST1H2AC HIST1H2AD HIST1H2AE HIST1H2AJ HIST1H2BA HIST1H2BB HIST1H2BC HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2BI HIST1H2BJ HIST1H2BK HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST1H3A HIST1H3B HIST1H3D HIST1H3E HIST1H3F HIST1H3G HIST1H3H HIST1H3I HIST1H3J HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H2AA HIST2H2AA3 HIST2H2AA4 HIST2H2AC HIST2H2BE HIST2H3A HIST2H3C HIST2H3D HIST2H4 HIST2H4A HIST2H4B HIST3H2BB HIST4H4 HLR1 HMT2 HNF3A HR21 HRMT1L2 HSP90A HSP90AA1 HSP90AB1 HSP90B HSPC1 HSPC2 HSPC3 HSPCA HSPCB HTATIP INO80S IR1B4 ITF JHDM3B JMJD2B JUN JUND KANK KANK1 KAT2B KAT5 KCTD6 KDM1 KDM1A KDM4B KIAA0078 KIAA0172 KIAA0178 KIAA0575 KIAA0601 KIAA0876 KIAA1093 KIAA1460 KIAA1547 KIAA1560 KIAA1567 KIAA1582 KIAA1631 KPNA2 LSD1 MED1 MOV10 MSG1 MYB MYC NCOA1 NCOA2 NCOA3 NR3A1 NR3C3 NR5A2 NRIP1 NXP1 OCT1 OTF1 P23 P300 PBP PCAF PGR POLR2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J1 POLR2K POLR2L POLRF POU2F1 PPARBP PPARGBP PRAD1 PRMT1 PRMT4 PS2 PTGES3 RAC3 RAD21 RAP30 RAP74 RB18A RCAS1 RCH1 RPB7 RPD3L1 RUNX1 SA1 SA2 SB1.8 SCC1 SCC3 SDF1 SDF1A SDF1B SMC1 SMC1A SMC1L1 SMC3 SMC3L1 SP1 SRC1 SRC2 SRP1 STAG1 STAG2 TAK TBP TCF3A TEBP TF2A1 TF2A2 TF2D TFF1 TFF3 TFI TFIID TGFA TIF2 TIP60 TLE3 TNRC6 TNRC6A TNRC6B TNRC6C TRAM1 TRAP220 TRIP2 TSFP1 TSH2B USF USF1 USF2 YY1 ZABC1 ZNF217
BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members	Apoptosis regulator Bcl-2 BH3-interacting domain death agonist Bcl-2-binding component 3, isoforms 1/2 Bcl-2-like protein 11 Bcl-2-like protein 1 Bcl-2-modifying factor Bcl2-associated agonist of cell death Phorbol-12-myristate-13-acetate-induced protein 1 Signal transducer and activator of transcription 3	O43521 P10415 P40763 P55957 Q07817 Q13794 Q92934 Q96LC9 Q9BXH1	APRF BAD BBC3 BBC6 BCL2 BCL2L BCL2L1 BCL2L11 BCL2L8 BCLX BID BIM BMF NOXA PMAIP1 PUMA STAT3
CLEC7A/inflammasome pathway	Apoptosis-associated speck-like protein containing a CARD Caspase-8 Interleukin-1 beta Mucosa-associated lymphoid tissue lymphoma translocation protein 1 Nuclear factor NF-kappa-B p105 subunit Transcription factor p65	P01584 P19838 Q04206 Q14790 Q9UDY8 Q9ULZ3	ASC CARD5 CASP8 IL1B IL1F2 MALT1 MCH5 MLT NFKB1 NFKB3 PYCARD RELA TMS1
Activation of PUMA and translocation to mitochondria	Apoptosis-stimulating of p53 protein 1 Apoptosis-stimulating of p53 protein 2 Bcl-2-binding component 3, isoforms 1/2 Cellular tumor antigen p53 Transcription factor Dp-1 Transcription factor Dp-2 Transcription factor E2F1 Tumor protein 63 Tumor protein p73	O15350 P04637 Q01094 Q13625 Q14186 Q14188 Q96KQ4 Q9BXH1 Q9H3D4	ASPP1 ASPP2 BBC3 BBP DP1 DP2 E2F1 KET KIAA0771 P53 P63 P73 P73H P73L PPP1R13B PUMA RBBP3 TFDP1 TFDP2 TP53 TP53BP2 TP63 TP73 TP73L
TP53 Regulates Transcription of Death Receptors and Ligands	Apoptosis-stimulating of p53 protein 1 Apoptosis-stimulating of p53 protein 2 Cellular tumor antigen p53 Insulin-like growth factor-binding protein 3 receptor Insulin-like growth factor-binding protein 3 Tumor necrosis factor receptor superfamily member 10A Tumor necrosis factor receptor superfamily member 10B Tumor necrosis factor receptor superfamily member 10C Tumor necrosis factor receptor superfamily member 10D Tumor necrosis factor receptor superfamily member 6 Tumor protein 63 Tumor protein p73	O00220 O14763 O14798 O15350 P04637 P17936 P25445 Q13625 Q86XT9 Q96KQ4 Q9H3D4 Q9UBN6	APO2 APT1 ASPP1 ASPP2 BBP DCR1 DCR2 DR4 DR5 FAS FAS1 IBP3 IGFBP3 KET KIAA0771 KILLER LIT P53 P63 P73 P73H P73L PPP1R13B TMEM219 TNFRSF10A TNFRSF10B TNFRSF10C TNFRSF10D TNFRSF6 TP53 TP53BP2 TP63 TP73 TP73L TRAILR1 TRAILR2 TRAILR3 TRAILR4 TRICK2 TRID TRUNDD ZTNFR9
Regulation of TP53 Activity through Association with Co-factors	Apoptosis-stimulating of p53 protein 1 Apoptosis-stimulating of p53 protein 2 Cellular tumor antigen p53 PHD finger protein 20 POU domain, class 4, transcription factor 1 POU domain, class 4, transcription factor 2 Protein BANP RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase RelA-associated inhibitor Tumor protein 63 Tumor protein p73 Zinc finger protein 385A	O15350 P04637 P31749 P31751 Q01851 Q12837 Q13625 Q8N9N5 Q8WUF5 Q96KQ4 Q96PM9 Q9BVI0 Q9H3D4 Q9Y243	AKT1 AKT2 AKT3 ASPP1 ASPP2 BANP BBP BEND1 BRN3A BRN3B C20orf104 GLEA2 HCA58 HZF IASPP KET KIAA0771 NKIP1 NZF P53 P63 P73 P73H P73L PHF20 PKB PKBG POU4F1 POU4F2 PPP1R13B PPP1R13BL PPP1R13L RAC RAI RDC1 RZF SMAR1 TP53 TP53BP2 TP63 TP73 TP73L TZP ZNF385 ZNF385A
Transcriptional Regulation by E2F6	Apoptotic protease-activating factor 1 Breast cancer type 1 susceptibility protein Cell division cycle 7-related protein kinase Chromobox protein homolog 3 Chromobox protein homolog 5 DNA endonuclease RBBP8 DNA repair protein RAD51 homolog 1 E3 ubiquitin-protein ligase RING1 E3 ubiquitin-protein ligase RING2 Enhancer of polycomb homolog 1 Histone-binding protein RBBP4 Histone-binding protein RBBP7 Histone-lysine N-methyltransferase EHMT1 Histone-lysine N-methyltransferase EHMT2 Histone-lysine N-methyltransferase EZH2 Lethal(3)malignant brain tumor-like protein 2 MAX gene-associated protein Polycomb complex protein BMI-1 Polycomb group RING finger protein 2 Polycomb group RING finger protein 6 Polycomb protein EED Polycomb protein SUZ12 Polyhomeotic-like protein 1 Polyhomeotic-like protein 3 Protein UXT Protein max RING1 and YY1-binding protein Ribonucleoside-diphosphate reductase subunit M2 Serine/threonine-protein kinase Chk1 Transcription factor Dp-1 Transcription factor Dp-2 Transcription factor E2F1 Transcription factor E2F6 YY1-associated factor 2	O00311 O14727 O14757 O75461 O75530 P31350 P35226 P35227 P38398 P45973 P61244 P78364 Q01094 Q06587 Q06609 Q09028 Q13185 Q14186 Q14188 Q15022 Q15910 Q16576 Q8IWI9 Q8IY57 Q8N488 Q8NDX5 Q969R5 Q96KQ7 Q99496 Q99708 Q9BYE7 Q9H2F5 Q9H9B1 Q9UBK9	APAF1 BAP1 BAT8 BHLHD4 BMI1 BRCA1 C6orf30 CBX3 CBX5 CDC7 CDC7L1 CHEK1 CHET9 CHK1 CTIP DEDAF DING DP1 DP2 E2F1 E2F6 EDR1 EDR3 EED EHMT1 EHMT2 EPC1 EUHMTASE1 EZH2 G9A GLP HIPI3 HP1A JJAZ1 KIAA0160 KIAA0413 KIAA0518 KIAA1876 KMT1C KMT1D KMT6 L3MBTL2 MAD5 MAX MBLR MEL18 MGA NG36 PCGF2 PCGF4 PCGF6 PH1 PH3 PHC1 PHC3 RAD51 RAD51A RBAP46 RBAP48 RBBP3 RBBP4 RBBP7 RBBP8 RECA RING1 RING1A RING1B RNF1 RNF110 RNF134 RNF2 RNF51 RNF53 RR2 RRM2 RYBP SUZ12 TFDP1 TFDP2 UXT YAF2 YEAF1 ZNF144
Regulation of the apoptosome activity	Apoptotic protease-activating factor 1 Caspase recruitment domain-containing protein 8 Caspase-9 Cell death regulator Aven Cytochrome c Diablo IAP-binding mitochondrial protein E3 ubiquitin-protein ligase XIAP Methylthioribulose-1-phosphate dehydratase Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Uveal autoantigen with coiled-coil domains and ankyrin repeats	O14727 P27361 P28482 P55211 P98170 P99999 Q96GX9 Q9BZF9 Q9NQS1 Q9NR28 Q9Y2G2	APAF1 API3 APIP AVEN BIRC4 CARD8 CASP9 CYC CYCS DACAR DIABLO ERK1 ERK2 IAP3 KIAA0413 KIAA0955 KIAA1561 MAPK1 MAPK3 MCH6 NDPP1 PRKM1 PRKM2 PRKM3 SMAC UACA XIAP
Formation of apoptosome	Apoptotic protease-activating factor 1 Caspase recruitment domain-containing protein 8 Caspase-9 Cell death regulator Aven Cytochrome c Methylthioribulose-1-phosphate dehydratase	O14727 P55211 P99999 Q96GX9 Q9NQS1 Q9Y2G2	APAF1 APIP AVEN CARD8 CASP9 CYC CYCS DACAR KIAA0413 KIAA0955 MCH6 NDPP1
TP53 Regulates Transcription of Caspase Activators and Caspases	Apoptotic protease-activating factor 1 Caspase-10 Caspase-1 Caspase-2 Caspase-6 Cellular tumor antigen p53 Death domain-containing protein CRADD NLR family CARD domain-containing protein 4 Serine-protein kinase ATM Tumor protein 63 Tumor protein p73 p53-induced death domain-containing protein 1	O14727 O15350 P04637 P29466 P42575 P55212 P78560 Q13315 Q92851 Q9H3D4 Q9HB75 Q9NPP4	APAF1 ATM CARD12 CASP1 CASP10 CASP2 CASP6 CLAN CLAN1 CRADD ICH1 IL1BC IL1BCE IPAF KET KIAA0413 LRDD MCH2 MCH4 NEDD2 NLRC4 P53 P63 P73 P73H P73L PIDD PIDD1 RAIDD TP53 TP63 TP73 TP73L
SMAC (DIABLO) binds to IAPs	Apoptotic protease-activating factor 1 Caspase-3 Caspase-7 Caspase-9 Cytochrome c Diablo IAP-binding mitochondrial protein E3 ubiquitin-protein ligase XIAP	O14727 P42574 P55210 P55211 P98170 P99999 Q9NR28	APAF1 API3 BIRC4 CASP3 CASP7 CASP9 CPP32 CYC CYCS DIABLO IAP3 KIAA0413 MCH3 MCH6 SMAC XIAP
SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes	Apoptotic protease-activating factor 1 Caspase-3 Caspase-7 Caspase-9 Cytochrome c Diablo IAP-binding mitochondrial protein E3 ubiquitin-protein ligase XIAP	O14727 P42574 P55210 P55211 P98170 P99999 Q9NR28	APAF1 API3 BIRC4 CASP3 CASP7 CASP9 CPP32 CYC CYCS DIABLO IAP3 KIAA0413 MCH3 MCH6 SMAC XIAP
Activation of caspases through apoptosome-mediated cleavage	Apoptotic protease-activating factor 1 Caspase-3 Caspase-7 Caspase-9 Cytochrome c E3 ubiquitin-protein ligase XIAP	O14727 P42574 P55210 P55211 P98170 P99999	APAF1 API3 BIRC4 CASP3 CASP7 CASP9 CPP32 CYC CYCS IAP3 KIAA0413 MCH3 MCH6 XIAP
Passive transport by Aquaporins	Aquaporin-10 Aquaporin-11 Aquaporin-12A Aquaporin-1 Aquaporin-2 Aquaporin-3 Aquaporin-4 Aquaporin-5 Aquaporin-6 Aquaporin-7 Aquaporin-8 Aquaporin-9 Lens fiber major intrinsic protein	O14520 O43315 O94778 P29972 P30301 P41181 P55064 P55087 Q13520 Q8IXF9 Q8NBQ7 Q92482 Q96PS8	AQP0 AQP1 AQP10 AQP11 AQP12 AQP12A AQP2 AQP2L AQP3 AQP4 AQP5 AQP6 AQP7 AQP7L AQP8 AQP9 AQPX1 AQPX2 CHIP28 MIP SSC1
Detoxification of Reactive Oxygen Species	Aquaporin-8 Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] Catalase Copper chaperone for superoxide dismutase Copper transport protein ATOX1 Copper-transporting ATPase 1 Cytochrome b-245 heavy chain Cytochrome b-245 light chain Cytochrome c ERO1-like protein alpha Epididymal secretory glutathione peroxidase Extracellular superoxide dismutase [Cu-Zn] Glutathione S-transferase P Glutathione peroxidase 1 Glutathione peroxidase 2 Glutathione peroxidase 3 Glutathione peroxidase 6 Glutathione peroxidase 7 NADPH oxidase 4 NADPH oxidase 5 Neutrophil cytosol factor 1 Neutrophil cytosol factor 2 Neutrophil cytosol factor 4 Peroxiredoxin-1 Peroxiredoxin-2 Peroxiredoxin-6 Probable glutathione peroxidase 8 Protein disulfide-isomerase Superoxide dismutase [Cu-Zn] Superoxide dismutase [Mn], mitochondrial Thioredoxin reductase 1, cytoplasmic Thioredoxin reductase 2, mitochondrial Thioredoxin, mitochondrial Thioredoxin-dependent peroxide reductase, mitochondrial Thioredoxin	O00244 O14618 O75715 O94778 P00441 P04040 P04179 P04839 P07203 P07237 P08294 P09211 P10599 P13498 P14598 P18283 P19878 P22352 P30041 P30048 P32119 P50583 P59796 P99999 Q04656 Q06830 Q15080 Q16881 Q8TED1 Q96HE7 Q96PH1 Q96SL4 Q99757 Q9NNW7 Q9NPH5	AOP1 AOP2 APAH1 AQP8 ATOX1 ATP7A CAT CCS CYBA CYBB CYC CYCS ERBA2L ERO1A ERO1L FAEES3 GPX1 GPX2 GPX3 GPX5 GPX6 GPX7 GPX8 GPXP GRIM12 GST3 GSTP1 HAH1 KDRF KIAA0106 KIAA1652 MC1 MNK NCF1 NCF2 NCF4 NKEFB NOX2 NOX4 NOX5 NOXA2 NOXO2 NUDT2 P4HB P67PHOX PAGA PAGB PDI PDIA1 PO4DB PRDX1 PRDX2 PRDX3 PRDX6 RENOX SH3PXD1A SH3PXD4 SOD1 SOD2 SOD3 TDPX1 TDPX2 TRDX TRX TRX1 TRX2 TRXR2 TXN TXN2 TXNRD1 TXNRD2
Synthesis of 12-eicosatetraenoic acid derivatives	Arachidonate 12-lipoxygenase, 12R-type Glutathione peroxidase 1 Glutathione peroxidase 2 Hydroperoxide isomerase ALOXE3 Phospholipid hydroperoxide glutathione peroxidase GPX4 Polyunsaturated fatty acid lipoxygenase ALOX12 Polyunsaturated fatty acid lipoxygenase ALOX15	O75342 P07203 P16050 P18054 P18283 P36969 Q9BYJ1	12LO ALOX12 ALOX12B ALOX15 ALOXE3 GPX1 GPX2 GPX4 LOG12 LOG15
Synthesis of Leukotrienes (LT) and Eoxins (EX)	Arachidonate 5-lipoxygenase-activating protein Cytochrome P450 4A11 Cytochrome P450 4A22 Cytochrome P450 4B1 Cytochrome P450 4F11 Cytochrome P450 4F2 Cytochrome P450 4F3 Cytochrome P450 4F8 Dipeptidase 1 Dipeptidase 2 Dipeptidase 3 Glutathione hydrolase 1 proenzyme Glutathione hydrolase 5 proenzyme Leukotriene A-4 hydrolase Leukotriene C4 synthase MAP kinase-activated protein kinase 2 Multidrug resistance-associated protein 1 Polyunsaturated fatty acid 5-lipoxygenase Polyunsaturated fatty acid lipoxygenase ALOX15 Prostaglandin reductase 1 Ultra-long-chain fatty acid omega-hydroxylase	P09917 P09960 P13584 P16050 P16444 P19440 P20292 P33527 P36269 P49137 P78329 P98187 Q02928 Q08477 Q14914 Q16873 Q5TCH4 Q6NT55 Q9H4A9 Q9H4B8 Q9HBI6	ABCC1 ALOX15 ALOX5 ALOX5AP CYP4A11 CYP4A2 CYP4A22 CYP4B1 CYP4F11 CYP4F2 CYP4F22 CYP4F3 CYP4F8 DPEP1 DPEP2 DPEP3 FLAP GGT GGT1 GGT5 GGTLA1 LOG15 LOG5 LTA4 LTA4H LTB4DH LTB4H LTC4S MAPKAPK2 MDP MRP MRP1 PTGR1 RDP
Synthesis of 5-eicosatetraenoic acids	Arachidonate 5-lipoxygenase-activating protein Glutathione peroxidase 1 Glutathione peroxidase 2 Leukotriene C4 synthase Phospholipid hydroperoxide glutathione peroxidase GPX4 Polyunsaturated fatty acid 5-lipoxygenase Serum paraoxonase/arylesterase 1 Serum paraoxonase/arylesterase 2 Serum paraoxonase/lactonase 3	P07203 P09917 P18283 P20292 P27169 P36969 Q15165 Q15166 Q16873	ALOX5 ALOX5AP FLAP GPX1 GPX2 GPX4 LOG5 LTC4S PON PON1 PON2 PON3
Netrin-1 signaling	Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 E3 ubiquitin-protein ligase SIAH1 E3 ubiquitin-protein ligase SIAH2 Ezrin Hemojuvelin Neogenin Netrin receptor DCC Netrin receptor UNC5A Netrin receptor UNC5B Netrin-1 Netrin-4 Protein kinase C theta type Repulsive guidance molecule A Repulsive guidance molecule B Roundabout homolog 1 Slit homolog 1 protein Slit homolog 2 protein Slit homolog 3 protein Unconventional myosin-X	O43255 O75093 O75094 O94813 O95631 P15311 P43146 Q04759 Q6NW40 Q6ZN44 Q6ZVN8 Q8IUQ4 Q8IZJ1 Q92859 Q96B86 Q99490 Q9HB63 Q9HD67 Q9Y6N7	AGAP2 CENTG1 DCC DUTT1 EZR HFE2 HJV HUMSIAH IGDCC1 IGDCC2 KIAA0167 KIAA0799 KIAA0813 KIAA0814 KIAA1976 MEGF4 MEGF5 MYO10 NEO1 NGN NTN1 NTN1L NTN4 P53RDL1 PRKCQ PRKCT RGM RGMA RGMB RGMC ROBO1 SIAH1 SIAH2 SLIL1 SLIL2 SLIL3 SLIT1 SLIT2 SLIT3 UNC5A UNC5B UNC5H1 UNC5H2 VIL2
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1	Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 Docking protein 1 E3 ubiquitin-protein ligase CBL Polyubiquitin-B Polyubiquitin-C Protein-tyrosine kinase 6 RAC-alpha serine/threonine-protein kinase Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	P0CG47 P0CG48 P22681 P31749 P62979 P62987 Q13882 Q96P48 Q99704	AKT1 ARAP1 BRK CBL CBL2 CENTD2 DOK1 KIAA0782 PKB PTK6 RAC RNF55 RPS27A UBA52 UBA80 UBB UBC UBCEP1 UBCEP2
Urea cycle	Arginase-1 Arginase-2, mitochondrial Argininosuccinate lyase Argininosuccinate synthase Carbamoyl-phosphate synthase [ammonia], mitochondrial Mitochondrial ornithine transporter 1 Mitochondrial ornithine transporter 2 N-acetylglutamate synthase, mitochondrial NmrA-like family domain-containing protein 1 Ornithine transcarbamylase, mitochondrial	P00480 P00966 P04424 P05089 P31327 P78540 Q8N159 Q9BXI2 Q9HBL8 Q9Y619	ARG1 ARG2 ASL ASS ASS1 CPS1 HSCARG NAGS NMRAL1 ORC1 ORC2 ORNT1 ORNT2 OTC SLC25A15 SLC25A2
Regulation of pyruvate metabolism	Armadillo repeat-containing protein 8 E3 ubiquitin-protein transferase MAEA E3 ubiquitin-protein transferase RMND5A E3 ubiquitin-protein transferase RMND5B Glucose-induced degradation protein 4 homolog Glucose-induced degradation protein 8 homolog L-lactate dehydrogenase A chain Muskelin NADP-dependent malic enzyme Polyubiquitin-B Polyubiquitin-C Ran-binding protein 9 Serine/threonine-protein kinase Nek1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein WD repeat-containing protein 26	P00338 P0CG47 P0CG48 P48163 P62979 P62987 Q7L5Y9 Q8IUR7 Q8IVV7 Q96G75 Q96PY6 Q96S59 Q9H7D7 Q9H871 Q9NWU2 Q9UL63	ARMC8 C17orf39 C20orf11 CDW2 EMP GID4 GID8 KIAA1901 LDHA MAEA ME1 MIP2 MKLN1 NEK1 RANBP9 RANBPM RMND5A RMND5B RPS27A TWA1 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 VID24 WDR26

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