GlyCosmos Portal

Homo sapiens (human)

Summary

Taxonomy ID: 9606
PubChem Taxonomy: 9606

Genes (1582) Glycans (5831) Glycoproteins (18496) Lectins (298) Pathways (2090)

Displaying entries **1026 - 1050** of **2090** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol
RHO GTPases regulate CFTR trafficking	Cystic fibrosis transmembrane conductance regulator Golgi-associated PDZ and coiled-coil motif-containing protein Rho-related GTP-binding protein RhoQ	P13569 P17081 Q9HD26	ABCC7 ARHQ CAL CFTR FIG GOPC RASL7A RHOQ TC10
G beta:gamma signalling through PLC beta	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5	O14610 O14775 O60262 P16520 P50150 P50151 P59768 P61952 P62873 P62879 P63211 P63215 P63218 Q00722 Q01970 Q9HAV0 Q9NQ66 Q9P2W3 Q9UBI6 Q9UK08	GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 KIAA0581 PLCB1 PLCB2 PLCB3
Defective SLC11A2 causes hypochromic microcytic anemia, with iron overload 1 (AHMIO1)	Natural resistance-associated macrophage protein 2	P49281	DCT1 DMT1 NRAMP2 SLC11A2
NFE2L2 regulating ER-stress associated genes	CREB-binding protein Cyclic AMP-dependent transcription factor ATF-4 Histone acetyltransferase p300 Nuclear factor erythroid 2-related factor 2 Transcription factor MafK	O60675 P18848 Q09472 Q16236 Q92793	ATF4 CBP CREB2 CREBBP EP300 MAFK NFE2L2 NRF2 P300 TXREB
Scavenging by Class H Receptors	Apolipoprotein B-100 SPARC Stabilin-1 Stabilin-2	P04114 P09486 Q8WWQ8 Q9NY15	APOB FEEL1 FEEL2 FELL FEX2 HARE KIAA0246 ON SPARC STAB1 STAB2
RAB GEFs exchange GTP for GDP on RABs	14-3-3 protein epsilon ALS2 C-terminal-like protein Alsin Ankyrin repeat domain-containing protein 27 BLOC-3 complex member HPS1 BLOC-3 complex member HPS4 C-myc promoter-binding protein DENN domain-containing protein 1A DENN domain-containing protein 1B DENN domain-containing protein 1C DENN domain-containing protein 2A DENN domain-containing protein 2B DENN domain-containing protein 2C DENN domain-containing protein 2D DENN domain-containing protein 3 DENN domain-containing protein 4B DENN domain-containing protein 4C DENN domain-containing protein 5A DENN domain-containing protein 5B GTPase-activating protein and VPS9 domain-containing protein 1 Guanine nucleotide exchange factor for Rab-3A Guanine nucleotide exchange factor subunit RIC1 Myotubularin-related protein 13 Myotubularin-related protein 5 Protein DENND6A Protein DENND6B RAB6A-GEF complex partner protein 2 RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Rab GDP dissociation inhibitor alpha Rab GDP dissociation inhibitor beta Rab proteins geranylgeranyltransferase component A 1 Rab proteins geranylgeranyltransferase component A 2 Rab-3A-interacting protein Rab3 GTPase-activating protein catalytic subunit Rab3 GTPase-activating protein non-catalytic subunit Rab5 GDP/GTP exchange factor Ras and Rab interactor 1 Ras and Rab interactor 2 Ras and Rab interactor 3 Ras and Rab interactor-like protein Ras-related protein Rab-10 Ras-related protein Rab-12 Ras-related protein Rab-13 Ras-related protein Rab-14 Ras-related protein Rab-18 Ras-related protein Rab-1A Ras-related protein Rab-1B Ras-related protein Rab-21 Ras-related protein Rab-27A Ras-related protein Rab-27B Ras-related protein Rab-31 Ras-related protein Rab-32 Ras-related protein Rab-35 Ras-related protein Rab-38 Ras-related protein Rab-39A Ras-related protein Rab-39B Ras-related protein Rab-3A Ras-related protein Rab-5A Ras-related protein Rab-5B Ras-related protein Rab-5C Ras-related protein Rab-6A Ras-related protein Rab-6B Ras-related protein Rab-7a Ras-related protein Rab-7b Ras-related protein Rab-8A Ras-related protein Rab-8B Ras-related protein Rab-9A Ras-related protein Rab-9B Serine/threonine-protein kinase ULK1 Trafficking protein particle complex subunit 10 Trafficking protein particle complex subunit 11 Trafficking protein particle complex subunit 12 Trafficking protein particle complex subunit 13 Trafficking protein particle complex subunit 1 Trafficking protein particle complex subunit 2-like protein Trafficking protein particle complex subunit 2 Trafficking protein particle complex subunit 3 Trafficking protein particle complex subunit 4 Trafficking protein particle complex subunit 5 Trafficking protein particle complex subunit 6A Trafficking protein particle complex subunit 6B Trafficking protein particle complex subunit 8 Trafficking protein particle complex subunit 9 Vacuolar fusion protein CCZ1 homolog B Vacuolar fusion protein CCZ1 homolog Vacuolar fusion protein MON1 homolog A Vacuolar fusion protein MON1 homolog B	A2RUS2 A5PLN9 O00194 O43617 O75064 O75385 O75865 O95248 P0DI81 P20336 P20339 P20340 P24386 P26374 P31150 P31749 P31751 P48553 P50395 P51148 P51149 P51151 P51153 P51159 P57729 P61006 P61020 P61026 P61106 P62258 P62820 P78524 P86790 P86791 Q13636 Q13637 Q13671 Q14964 Q14C86 Q15042 Q15286 Q4ADV7 Q5VZ89 Q60I27 Q68D51 Q6IQ22 Q6IQ26 Q6P3S1 Q6ZS11 Q6ZUT9 Q7L1V2 Q7Z392 Q7Z401 Q86SZ2 Q86VX9 Q86WG5 Q8IUR0 Q8IV53 Q8IWF6 Q8NEG7 Q8TB24 Q8TBN0 Q8TEH3 Q8WVT3 Q8WYP3 Q92546 Q92902 Q92930 Q96AH8 Q96DA2 Q96NW4 Q96Q05 Q96Q42 Q96QF0 Q9H0U4 Q9H2M9 Q9H6A0 Q9NP72 Q9NP90 Q9NQG7 Q9NRW1 Q9UJ41 Q9UL25 Q9UL33 Q9ULE3 Q9Y243 Q9Y296 Q9Y2L5 Q9Y5R8	AKT1 AKT2 AKT3 ALS2 ALS2CL ALS2CR6 ANKRD27 BET3 BET5 C1orf218 C4orf41 C5orf44 C7orf28A C7orf28B C9orf55 C9orf55B CCZ1 CCZ1B CHM CHML CIP150 CMT4B2 DENND1A DENND1B DENND1C DENND2A DENND2B DENND2C DENND2D DENND3 DENND4A DENND4B DENND4C DENND5A DENND5B DENND6A DENND6B EHOC1 FAM116A FAM116B FAM31A FAM31B FAM31C GAPEX5 GAPVD1 GDI1 GDI2 GDIL HPS HPS1 HPS4 HSRG1 HTS1 IRLB KIAA0066 KIAA0118 KIAA0258 KIAA0476 KIAA0722 KIAA0839 KIAA0870 KIAA0872 KIAA1012 KIAA1091 KIAA1277 KIAA1432 KIAA1521 KIAA1563 KIAA1608 KIAA1667 KIAA1766 KIAA1882 MEL MON1A MON1B MTMR13 MTMR5 MUM2 MYCPBP NIBP OPHN2 PKB PKBG RAB1 RAB10 RAB12 RAB13 RAB14 RAB18 RAB1A RAB1B RAB1C RAB21 RAB22B RAB27 RAB27A RAB27B RAB31 RAB32 RAB35 RAB38 RAB39 RAB39A RAB39B RAB3A RAB3GAP RAB3GAP1 RAB3GAP2 RAB3IL1 RAB3IP RAB5 RAB5A RAB5B RAB5C RAB6 RAB6A RAB6B RAB6IP1 RAB7 RAB7A RAB7B RAB8 RAB8A RAB8B RAB9 RAB9A RAB9B RAB9L RABEX5 RABGDIA RABGDIB RABGEF1 RABIN8 RABL RAC RAP6 RASSF4 RAY REP1 REP2 RGP1 RIC1 RIN1 RIN2 RIN3 RINL SAND1 SAND2 SBDN SBF1 SBF2 SEDL ST5 TCD TMEM1 TRAMM TRAPPC1 TRAPPC10 TRAPPC11 TRAPPC12 TRAPPC13 TRAPPC2 TRAPPC2L TRAPPC3 TRAPPC4 TRAPPC5 TRAPPC6A TRAPPC6B TRAPPC8 TRAPPC9 TTC15 ULK1 XAP4 YWHAE
Defective B3GALT6 causes EDSP2 and SEMDJL1	Agrin Basement membrane-specific heparan sulfate proteoglycan core protein Beta-1,3-galactosyltransferase 6 Biglycan Brevican core protein Chondroitin sulfate proteoglycan 4 Chondroitin sulfate proteoglycan 5 Decorin Glypican-1 Glypican-2 Glypican-3 Glypican-4 Glypican-5 Glypican-6 Neurocan core protein Syndecan-1 Syndecan-2 Syndecan-3 Syndecan-4 Versican core protein	O00468 O14594 O75056 O75487 O95196 P07585 P13611 P18827 P21810 P31431 P34741 P35052 P51654 P78333 P98160 Q6UVK1 Q8N158 Q96GW7 Q96L58 Q9Y625	AGRIN AGRN B3GALT6 BCAN BEHAB BGN CALEB CSPG2 CSPG3 CSPG4 CSPG5 CSPG7 DCN GPC1 GPC2 GPC3 GPC4 GPC5 GPC6 HSPG1 HSPG2 KIAA0468 MCSP NCAN NEUR NGC OCI5 SDC SDC1 SDC2 SDC3 SDC4 SLRR1A SLRR1B VCAN
Heme signaling	3'-5' exoribonuclease HELZ2 Apolipoprotein A-I Apolipoprotein B-100 Basic helix-loop-helix ARNT-like protein 1 C-type lectin domain family 1 member B CREB-binding protein CREB-regulated transcription coactivator 1 CREB-regulated transcription coactivator 2 CREB-regulated transcription coactivator 3 Chromodomain-helicase-DNA-binding protein 9 Circadian locomoter output cycles protein kaput Cyclic AMP-dependent transcription factor ATF-2 Exportin-1 F-box-like/WD repeat-containing protein TBL1X F-box-like/WD repeat-containing protein TBL1XR1 Heme oxygenase 1 Hemoglobin subunit alpha Hemoglobin subunit beta Histone acetyltransferase p300 Histone deacetylase 3 Histone-arginine methyltransferase CARM1 Lymphocyte antigen 96 Mediator of RNA polymerase II transcription subunit 1 Membrane-associated progesterone receptor component 2 Myocyte-specific enhancer factor 2C Myocyte-specific enhancer factor 2D NAD-dependent protein deacetylase sirtuin-1 Neuronal PAS domain-containing protein 2 Nuclear factor erythroid 2-related factor 2 Nuclear receptor ROR-alpha Nuclear receptor coactivator 1 Nuclear receptor coactivator 2 Nuclear receptor coactivator 6 Nuclear receptor corepressor 1 Nuclear receptor subfamily 1 group D member 1 Nuclear receptor-interacting protein 1 Peroxisome proliferator-activated receptor alpha Peroxisome proliferator-activated receptor gamma coactivator 1-alpha Proton-coupled folate transporter Retinoic acid receptor RXR-alpha Retinoic acid-induced protein 1 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 Toll-like receptor 4 Transcription factor MafK Transcription regulator protein BACH1 Trimethylguanosine synthase	O00206 O00327 O14867 O14980 O15173 O15379 O15516 O60675 O60907 O75376 P02647 P04114 P09601 P15336 P19793 P20393 P35398 P48552 P68871 P69905 Q06413 Q07869 Q09472 Q14686 Q14814 Q15596 Q15648 Q15788 Q16236 Q3L8U1 Q53ET0 Q6STE5 Q6UUV7 Q6UUV9 Q7Z5J4 Q86X55 Q92793 Q96EB6 Q96NT5 Q96RS0 Q99743 Q9BYK8 Q9BZK7 Q9P126 Q9UBK2 Q9Y6Y9	AIB3 APOA1 APOB ARC205 ARNTL ATF2 BACH1 BAF60C BHLHE5 BHLHE74 BHLHE75 BHLHE8 BHLHE9 BMAL1 CARM1 CBP CHD9 CLEC1B CLEC2 CLOCK CREB2 CREBBP CREBP1 CRM1 CRSP1 CRSP200 CRTC1 CRTC2 CRTC3 DG6 DRIP205 DRIP230 EAR1 EP300 ESOP1 G21 HBA1 HBA2 HBB HCA137 HCP1 HDAC3 HELZ2 HMOX1 HO HO1 HREV IRA1 KIAA0181 KIAA0308 KIAA0334 KIAA0616 KIAA1047 KIAA1769 KIAA1820 KISH2 LEM6 LY96 MAFK MD2 MECT1 MED1 MEF2C MEF2D MOP3 MOP4 NCOA1 NCOA2 NCOA6 NCOA6IP NCOR1 NFE2L2 NPAS2 NR1C1 NR1D1 NR1F1 NR2B1 NRF2 NRIP1 P300 PASD3 PASD4 PBP PCFT PGC1 PGC1A PGRMC2 PIMT PMBP PPAR PPARA PPARBP PPARGBP PPARGC1 PPARGC1A PRIC285 PRIC320 PRMT4 RAI1 RAP250 RB18A RORA RXRA RZRA SIR2L1 SIRT1 SLC46A1 SMARCD3 SRC1 SRC2 TBL1 TBL1X TBL1XR1 TBLR1 TGS1 THRAL TIF2 TLR4 TORC1 TORC2 TORC3 TRAP220 TRBP TRIP2 WAMTP1 XPO1
CD28 dependent Vav1 pathway	Cell division control protein 42 homolog Proto-oncogene vav Ras-related C3 botulinum toxin substrate 1 Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 2 Serine/threonine-protein kinase PAK 3 T-cell-specific surface glycoprotein CD28 T-lymphocyte activation antigen CD80 T-lymphocyte activation antigen CD86 Tyrosine-protein kinase Fyn Tyrosine-protein kinase Lck	O75914 P06239 P06241 P10747 P15498 P33681 P42081 P60953 P63000 Q13153 Q13177	CD28 CD28LG CD28LG1 CD28LG2 CD80 CD86 CDC42 FYN LAB7 LCK OPHN3 PAK1 PAK2 PAK3 RAC1 TC25 VAV VAV1
Downregulation of TGF-beta receptor signaling	BMP and activin membrane-bound inhibitor homolog E3 ubiquitin-protein ligase CHIP E3 ubiquitin-protein ligase NEDD4-like E3 ubiquitin-protein ligase SMURF1 E3 ubiquitin-protein ligase SMURF2 Exportin-1 Mothers against decapentaplegic homolog 2 Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 7 Myotubularin-related protein 4 Polyubiquitin-B Polyubiquitin-C Protein TMEPAI Protein phosphatase 1 regulatory subunit 15A Serine-threonine kinase receptor-associated protein Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Serine/threonine-protein phosphatase PP1-beta catalytic subunit Serine/threonine-protein phosphatase PP1-gamma catalytic subunit TGF-beta receptor type-1 TGF-beta receptor type-2 Transforming growth factor beta-1 proprotein Ubiquitin carboxyl-terminal hydrolase 15 Ubiquitin carboxyl-terminal hydrolase isozyme L5 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O14980 O15105 O75807 P01137 P0CG47 P0CG48 P36873 P36897 P37173 P62136 P62140 P62979 P62987 P84022 Q13145 Q15796 Q969W9 Q96PU5 Q9HAU4 Q9HCE7 Q9NYA4 Q9UNE7 Q9Y3F4 Q9Y4E8 Q9Y5K5	ALK5 BAMBI CHIP CRM1 GADD34 KIAA0439 KIAA0529 KIAA0647 KIAA1625 MADH2 MADH3 MADH7 MADH8 MADR2 MAWD MTMR4 NEDD4L NEDL3 NMA PMEPA1 PPP1A PPP1CA PPP1CB PPP1CC PPP1R15A RPS27A SKR4 SMAD2 SMAD3 SMAD7 SMURF1 SMURF2 STAG1 STRAP STUB1 TGFB TGFB1 TGFBR1 TGFBR2 TMEPAI UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 UCH37 UCHL5 UNRIP USP15 XPO1 ZFYVE11
SUMO is transferred from E1 to E2 (UBE2I, UBC9)	RWD domain-containing protein 3 SUMO-activating enzyme subunit 1 SUMO-activating enzyme subunit 2 SUMO-conjugating enzyme UBC9 Small ubiquitin-related modifier 1 Small ubiquitin-related modifier 2 Small ubiquitin-related modifier 3	P55854 P61956 P63165 P63279 Q9UBE0 Q9UBT2 Q9Y3V2	AOS1 RSUME RWDD3 SAE1 SAE2 SMT3A SMT3B SMT3C SMT3H1 SMT3H2 SMT3H3 SUA1 SUMO1 SUMO2 SUMO3 UBA2 UBC9 UBCE9 UBE2I UBL1 UBLE1A UBLE1B
AXIN missense mutants destabilize the destruction complex	APC membrane recruitment protein 1 Adenomatous polyposis coli protein Axin-1 Casein kinase I isoform alpha Glycogen synthase kinase-3 beta Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform	O15169 P25054 P30153 P30154 P48729 P49841 P62714 P67775 Q13362 Q14738 Q15172 Q15173 Q16537 Q5JTC6	AMER1 APC AXIN AXIN1 CSNK1A1 DP2.5 FAM123B GSK3B KIAA0044 PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E WTX
RNA Polymerase I Transcription Termination	CDK-activating kinase assembly factor MAT1 Caveolae-associated protein 1 Cyclin-H Cyclin-dependent kinase 7 DNA-directed RNA polymerase I subunit RPA12 DNA-directed RNA polymerase I subunit RPA1 DNA-directed RNA polymerase I subunit RPA2 DNA-directed RNA polymerase I subunit RPA34 DNA-directed RNA polymerase I subunit RPA43 DNA-directed RNA polymerase I subunit RPA49 DNA-directed RNA polymerases I and III subunit RPAC1 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 General transcription and DNA repair factor IIH helicase subunit XPD General transcription and DNA repair factor IIH helicase/translocase subunit XPB General transcription factor IIH subunit 1 General transcription factor IIH subunit 2 General transcription factor IIH subunit 3 General transcription factor IIH subunit 4 General transcription factor IIH subunit 5 Nucleolar transcription factor 1 Protein POLR1D, isoform 2 TATA box-binding protein-associated factor RNA polymerase I subunit A TATA box-binding protein-associated factor RNA polymerase I subunit B TATA box-binding protein-associated factor RNA polymerase I subunit C TATA box-binding protein-associated factor RNA polymerase I subunit D TATA-box-binding protein Transcription termination factor 1	O15160 O15446 O95602 P0DPB5 P17480 P18074 P19388 P19447 P20226 P32780 P50613 P51946 P51948 P52434 P53803 P61218 P62875 Q13888 Q13889 Q15361 Q15572 Q15573 Q3B726 Q53T94 Q6NZI2 Q6ZYL4 Q92759 Q9GZS1 Q9H5J8 Q9H9Y6 Q9P1U0	ASE1 BTF2 BTF2P44 C6orf175 CAK CAK1 CAP35 CAST CAVIN1 CCNH CD3EAP CDK7 CDKN7 ERCC2 ERCC3 GTF2D1 GTF2H1 GTF2H2 GTF2H3 GTF2H4 GTF2H5 JOSD3 MAT1 MNAT1 MO15 PAF49 PAF53 POLR1A POLR1B POLR1C POLR1D POLR1E POLR1F POLR1G POLR1H POLR2E POLR2F POLR2H POLR2K POLR2L POLRF PRAF1 PTRF RNF66 RPA12 STK1 TAF1A TAF1B TAF1C TAF1D TBP TF2D TFIID TTDA TTF1 TWISTNB UBF UBF1 UBTF XPB XPBC XPD XPDC ZNRD1
Dectin-1 mediated noncanonical NF-kB signaling	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Cullin-1 F-box/WD repeat-containing protein 11 F-box/WD repeat-containing protein 1A Inhibitor of nuclear factor kappa-B kinase subunit alpha Mitogen-activated protein kinase kinase kinase 14 NEDD8-activating enzyme E1 catalytic subunit NEDD8-conjugating enzyme Ubc12 Nuclear factor NF-kappa-B p100 subunit Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 S-phase kinase-associated protein 1 Transcription factor RelB Transcription factor p65 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A5LHX3 O00231 O00232 O00233 O00487 O14818 O15111 O43242 O75832 P0CG47 P0CG48 P17980 P20618 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P35998 P40306 P43686 P48556 P49720 P49721 P51665 P55036 P60896 P60900 P61081 P61289 P62191 P62195 P62333 P62979 P62987 P63208 Q00653 Q01201 Q04206 Q06323 Q13200 Q13616 Q14997 Q15008 Q16401 Q8TAA3 Q8TBC4 Q92530 Q99436 Q99460 Q99558 Q9UKB1 Q9UL46 Q9UNM6 Q9Y297	BTRC BTRCP BTRCP2 C7orf76 CHUK CUL1 DSS1 EMC19 FBW1A FBW1B FBXW11 FBXW1A FBXW1B HC2 HC3 HC8 HC9 HSPC IFI5111 IKKA KIAA0072 KIAA0077 KIAA0107 KIAA0696 LMP10 LMP2 LMP7 LMPX LMPY LYT10 MAP3K14 MB1 MCB1 MECL1 MIP224 MOV34L MSS1 NFKB2 NFKB3 NIK NU OCP2 PFAAP4 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 RELA RELB RING10 RING12 RPS27A SEM1 SHFDG1 SHFM1 SKP1 SKP1A SUG1 SUG2 TBP1 TBP7 TCEB1L TCF16 TRAP2 UBA3 UBA52 UBA80 UBB UBC UBC12 UBCEP1 UBCEP2 UBE1C UBE2M X Y Y2 Z
Manipulation of host energy metabolism	6 kDa early secretory antigenic target Alpha-enolase Phosphoglycerate kinase 1	P00558 P06733 P9WNK7	ENO1 ENO1L1 MBPB1 MPB1 PGK1 PGKA esaT6 esxA
crenolanib-resistant FLT3 mutants	Receptor-type tyrosine-protein kinase FLT3	P36888	CD135 FLK2 FLT3 STK1
SHC-mediated cascade:FGFR3	Fibroblast growth factor 16 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 4 Fibroblast growth factor 9 GTPase HRas GTPase NRas Son of sevenless homolog 1	O43320 O76093 P01111 P01112 P05230 P08620 P09038 P31371 Q07889 Q9GZV9 Q9NP95	FGF1 FGF16 FGF18 FGF2 FGF20 FGF23 FGF4 FGF9 FGFA FGFB HRAS HRAS1 HST HSTF1 HYPF KS3 NRAS SOS1
RHOBTB3 ATPase cycle	Cullin-3 G1/S-specific cyclin-E1 Hepatocyte growth factor-regulated tyrosine kinase substrate Leucine-rich repeat-containing protein 41 Perilipin-3 Ras-related protein Rab-9A Ras-related protein Rab-9B Rho-related BTB domain-containing protein 3 von Hippel-Lindau disease tumor suppressor	O14964 O60664 O94955 P24864 P40337 P51151 Q13618 Q15345 Q9NP90	CCNE CCNE1 CUL3 HGS HRS KIAA0617 KIAA0878 LRRC41 M6PRBP1 MUF1 PLIN3 RAB9 RAB9A RAB9B RAB9L RHOBTB3 TIP47 VHL
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Anaphase-promoting complex subunit 10 Anaphase-promoting complex subunit 11 Anaphase-promoting complex subunit 15 Anaphase-promoting complex subunit 16 Anaphase-promoting complex subunit 1 Anaphase-promoting complex subunit 2 Anaphase-promoting complex subunit 4 Anaphase-promoting complex subunit 5 Anaphase-promoting complex subunit 7 Anaphase-promoting complex subunit CDC26 Aurora kinase A Aurora kinase B Cell division cycle protein 16 homolog Cell division cycle protein 20 homolog Cell division cycle protein 23 homolog Cell division cycle protein 27 homolog Fizzy-related protein homolog Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Retinoblastoma-associated protein S-phase kinase-associated protein 2 Securin Serine/threonine-protein kinase PLK1 Ubiquitin-conjugating enzyme E2 C Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 E1 Ubiquitin-conjugating enzyme E2 S Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A5LHX3 O00231 O00232 O00233 O00487 O00762 O14818 O14965 O43242 O75832 O95997 P06400 P0CG47 P0CG48 P17980 P20618 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P30260 P35998 P40306 P43686 P48556 P49720 P49721 P51665 P51668 P51965 P53350 P55036 P60006 P60896 P60900 P61289 P62191 P62195 P62333 P62979 P62987 Q06323 Q12834 Q13042 Q13200 Q13309 Q14997 Q15008 Q16401 Q16763 Q8NHZ8 Q8TAA3 Q92530 Q96DE5 Q96GD4 Q99436 Q99460 Q9H1A4 Q9NYG5 Q9UJX2 Q9UJX3 Q9UJX4 Q9UJX5 Q9UJX6 Q9UL46 Q9UM11 Q9UM13 Q9UNM6	AIK AIK2 AIM1 AIRK1 AIRK2 ANAPC1 ANAPC10 ANAPC11 ANAPC12 ANAPC15 ANAPC16 ANAPC2 ANAPC3 ANAPC4 ANAPC5 ANAPC6 ANAPC7 ANAPC8 APC10 APC2 APC4 APC5 APC7 ARK1 ARK2 AURA AURKA AURKB AYK1 BTAK C10orf104 C11orf51 C7orf76 C9orf17 CDC16 CDC20 CDC23 CDC26 CDC27 CDH1 CENP-27 D0S1430E D17S978E DSS1 E2EPF EAP1 FBXL1 FYR FZR FZR1 HC2 HC3 HC8 HC9 HSPC IAK1 IFI5111 KIAA0072 KIAA0077 KIAA0107 KIAA1242 KIAA1406 LMP10 LMP2 LMP7 LMPX LMPY MB1 MCB1 MECL1 MIP224 MOV34L MSS1 NU PFAAP4 PLK PLK1 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 PTTG PTTG1 RB1 RING10 RING12 RPS27A SEM1 SFT SHFDG1 SHFM1 SKP2 STK1 STK12 STK15 STK5 STK6 SUG1 SUG2 TBP1 TBP7 TRAP2 TSG24 TUTR1 UBA52 UBA80 UBB UBC UBC5A UBCEP1 UBCEP2 UBCH10 UBCH5 UBCH5A UBCH6 UBE2C UBE2D1 UBE2E1 UBE2S X Y Y2 Z
Cross-presentation of soluble exogenous antigens (endosomes)	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 C-type lectin domain family 4 member K C-type mannose receptor 2 High affinity immunoglobulin gamma Fc receptor I Macrophage mannose receptor 1 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Putative high affinity immunoglobulin gamma Fc receptor IB	A5LHX3 O00231 O00232 O00233 O00487 O14818 O43242 O75832 P12314 P17980 P20618 P22897 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P35998 P40306 P43686 P48556 P49720 P49721 P51665 P55036 P60896 P60900 P61289 P62191 P62195 P62333 Q06323 Q13200 Q14997 Q15008 Q16401 Q8TAA3 Q92530 Q92637 Q99436 Q99460 Q9UBG0 Q9UJ71 Q9UL46 Q9UNM6	C7orf76 CD207 CLEC13D CLEC13DL CLEC13E CLEC4K DSS1 ENDO180 FCG1 FCGR1 FCGR1A FCGR1B FCGR1BP HC2 HC3 HC8 HC9 HSPC IFI5111 IGFR1 IGFRB KIAA0072 KIAA0077 KIAA0107 KIAA0709 LMP10 LMP2 LMP7 LMPX LMPY MB1 MCB1 MECL1 MIP224 MOV34L MRC1 MRC1L1 MRC2 MSS1 NU PFAAP4 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 RING10 RING12 SEM1 SHFDG1 SHFM1 SUG1 SUG2 TBP1 TBP7 TRAP2 UPARAP X Y Y2 Z
DNA Damage Recognition in GG-NER	Actin, cytoplasmic 1 Actin-like protein 6A Actin-related protein 5 Actin-related protein 8 COP9 signalosome complex subunit 1 COP9 signalosome complex subunit 2 COP9 signalosome complex subunit 3 COP9 signalosome complex subunit 4 COP9 signalosome complex subunit 5 COP9 signalosome complex subunit 6 COP9 signalosome complex subunit 7a COP9 signalosome complex subunit 7b COP9 signalosome complex subunit 8 Centrin-2 Chromatin-remodeling ATPase INO80 Cullin-4A Cullin-4B DNA damage-binding protein 1 DNA damage-binding protein 2 DNA repair protein complementing XP-C cells E3 ubiquitin-protein ligase RBX1 INO80 complex subunit B INO80 complex subunit C INO80 complex subunit D INO80 complex subunit E Microspherule protein 1 Nuclear factor related to kappa-B-binding protein Poly [ADP-ribose] polymerase 1 Poly [ADP-ribose] polymerase 2 Polyubiquitin-B Polyubiquitin-C RuvB-like 1 TCF3 fusion partner Transcriptional repressor protein YY1 UV excision repair protein RAD23 homolog A UV excision repair protein RAD23 homolog B Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O96019 P09874 P0C1Z6 P0CG47 P0CG48 P25490 P41208 P54725 P54727 P60709 P61201 P62877 P62979 P62987 Q01831 Q13098 Q13619 Q13620 Q16531 Q53TQ3 Q6P4R8 Q6PI98 Q7L5N1 Q8NBZ0 Q92466 Q92905 Q96EZ8 Q99627 Q9BT78 Q9C086 Q9H981 Q9H9F9 Q9H9Q2 Q9UBW8 Q9UGN5 Q9ULG1 Q9UNS2 Q9Y265	ACTB ACTL6A ACTR5 ACTR8 ADPRT ADPRT2 ADPRTL2 ARP5 ARP8 BAF53 BAF53A C18orf37 CALT CCDC95 CEN2 CETN2 COPS1 COPS2 COPS3 COPS4 COPS5 COPS6 COPS7A COPS7B COPS8 CSN1 CSN2 CSN3 CSN4 CSN5 CSN6 CSN7A CSN7B CSN8 CUL4A CUL4B DDB1 DDB2 DERP10 GPS1 HMGA1L4 HVIP INO80 INO80A INO80B INO80C INO80D INO80E INO80F INO80G INO80H INO80K INO80N INO80Q INO80S INOC1 JAB1 KIAA0695 KIAA1259 MCRS1 MSP58 NFRKB NMP238 PAPA1 PARP1 PARP2 PPOL RAD23A RAD23B RBX1 RNF75 ROC1 RPS27A RUVBL1 TFPT TIP49 TIP49A TRIP15 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 XAP1 XPC XPCC YY1 ZNHIT4
Uncoating of the Influenza Virion	Hemagglutinin Matrix protein 1 Matrix protein 2 Neuraminidase Nuclear export protein Nucleoprotein Polymerase acidic protein Polymerase basic protein 2 RNA-directed RNA polymerase catalytic subunit	P03428 P03431 P03433 P03452 P03466 P03468 P03485 P03508 P06821	HA M NA NP NS PA PB1 PB2
Apoptotic execution phase	B-cell receptor-associated protein 31 Caspase-8 Dynamin-1-like protein Serine/threonine-protein kinase 24	O00429 P51572 Q14790 Q9Y6E0	BAP31 BCAP31 CASP8 DLP1 DNM1L DRP1 DXS1357E MCH5 MST3 STK24 STK3
Defective SLC6A19 causes Hartnup disorder (HND)	Sodium-dependent neutral amino acid transporter B(0)AT1	Q695T7	B0AT1 SLC6A19
Fibronectin matrix formation	Carcinoembryonic antigen-related cell adhesion molecule 1 Carcinoembryonic antigen-related cell adhesion molecule 6 Carcinoembryonic antigen-related cell adhesion molecule 8 Fibronectin Integrin alpha-5 Integrin beta-1	P02751 P05556 P08648 P13688 P31997 P40199	BGP BGP1 CEACAM1 CEACAM6 CEACAM8 CGM6 FN FN1 FNRA FNRB ITGA5 ITGB1 MDF2 MSK12 NCA

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