GlyCosmos Portal

Homo sapiens (human)

Summary

Taxonomy ID: 9606
PubChem Taxonomy: 9606

Genes (10109) Glycans (5831) Glycoproteins (15837) Lectins (297) Pathways (2074)

Displaying entries **1726 - 1750** of **2074** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol
Synthesis of PG	5'-3' exonuclease PLD3 5'-3' exonuclease PLD4 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial Mitochondrial cardiolipin hydrolase Phosphatidate cytidylyltransferase 2 Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 Phospholipase D1 Phospholipase D2	O14939 O95674 Q13393 Q32NB8 Q8IV08 Q8N2A8 Q8WUK0 Q96BZ4	C14orf175 CDS2 MOSP PGS1 PLD1 PLD2 PLD3 PLD4 PLD6 PLIP PTPMT1
Rap1 signalling	14-3-3 protein beta/alpha 14-3-3 protein zeta/delta RAF proto-oncogene serine/threonine-protein kinase RAS guanyl-releasing protein 1 RAS guanyl-releasing protein 2 Rap guanine nucleotide exchange factor 3 Rap guanine nucleotide exchange factor 4 Rap1 GTPase-activating protein 1 Rap1 GTPase-activating protein 2 Ras-related protein Rap-1A Ras-related protein Rap-1b Signal-induced proliferation-associated protein 1 cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit gamma	O95267 O95398 P04049 P17612 P22612 P22694 P31946 P47736 P61224 P62834 P63104 Q684P5 Q7LDG7 Q8WZA2 Q96FS4	CDC25L CGEF1 CGEF2 EPAC EPAC1 EPAC2 GARNL4 KIAA0474 KIAA1039 KREV1 MCG7 PKACA PRKACA PRKACB PRKACG RAF RAF1 RAP1A RAP1B RAP1GA1 RAP1GA2 RAP1GAP RAP1GAP2 RAPGEF3 RAPGEF4 RASGRP RASGRP1 RASGRP2 SIPA1 SPA1 YWHAB YWHAZ
Tyrosine catabolism	4-hydroxyphenylpyruvate dioxygenase Fumarylacetoacetase Homogentisate 1,2-dioxygenase Maleylacetoacetate isomerase Tyrosine aminotransferase	O43708 P16930 P17735 P32754 Q93099	FAH GSTZ1 HGD HGO HPD MAAI PPD TAT
POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation	Developmental pluripotency-associated protein 4 Ephrin type-A receptor 1 Fibroblast growth factor 2 Forkhead box protein D3 Homeobox protein NANOG POU domain, class 5, transcription factor 1 Protein Cripto Sal-like protein 1 Sal-like protein 4 Signal transducer and activator of transcription 3 Transcription factor SOX-2 Zinc finger protein ZIC 3	O60481 P09038 P13385 P21709 P40763 P48431 Q01860 Q7L190 Q9H9S0 Q9NSC2 Q9UJQ4 Q9UJU5	APRF CRIPTO CRIPTO-1 DPPA4 EPH EPHA1 EPHT EPHT1 FGF2 FGFB FOXD3 HFH2 NANOG OCT3 OCT4 OTF3 POU5F1 SAL1 SALL1 SALL4 SOX2 STAT3 TDGF1 ZIC3 ZNF203 ZNF794 ZNF797
TWIK-releated acid-sensitive K+ channel (TASK)	Potassium channel subfamily K member 3 Potassium channel subfamily K member 9	O14649 Q9NPC2	KCNK3 KCNK9 TASK TASK1 TASK3
ATF6 (ATF6-alpha) activates chaperones	Cyclic AMP-dependent transcription factor ATF-6 alpha Endoplasmic reticulum chaperone BiP Membrane-bound transcription factor site-1 protease Membrane-bound transcription factor site-2 protease	O43462 P11021 P18850 Q14703	ATF6 GRP78 HSPA5 KIAA0091 MBTPS1 MBTPS2 S1P S2P SKI1
Variant SLC6A20 contributes towards hyperglycinuria (HG) and iminoglycinuria (IG)	Sodium- and chloride-dependent transporter XTRP3	Q9NP91	SIT1 SLC6A20 XT3 XTRP3
Cross-presentation of soluble exogenous antigens (endosomes)	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 C-type lectin domain family 4 member K C-type mannose receptor 2 High affinity immunoglobulin gamma Fc receptor I Macrophage mannose receptor 1 Proteasomal ubiquitin receptor ADRM1 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Putative high affinity immunoglobulin gamma Fc receptor IB	O00231 O00232 O00487 O14818 O43242 P12314 P17980 P20618 P22897 P25786 P25787 P25788 P25789 P28066 P28070 P28072 P28074 P35998 P43686 P48556 P49720 P49721 P51665 P60896 P60900 P62191 P62195 P62333 Q13200 Q15008 Q16186 Q92637 Q99436 Q99460 Q9UBG0 Q9UJ71 Q9UNM6	ADRM1 C7orf76 CD207 CLEC13D CLEC13DL CLEC13E CLEC4K DSS1 ENDO180 FCG1 FCGR1 FCGR1A FCGR1B FCGR1BP GP110 HC2 HC3 HC8 HC9 HSPC IGFR1 IGFRB KIAA0107 KIAA0709 LMPX LMPY MB1 MIP224 MOV34L MRC1 MRC1L1 MRC2 MSS1 NU PFAAP4 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PSMD8 SEM1 SHFDG1 SHFM1 SUG1 SUG2 TBP1 TBP7 TRAP2 UPARAP X Y Z
Membrane binding and targetting of GAG proteins	Gag polyprotein Glycylpeptide N-tetradecanoyltransferase 2 Multivesicular body subunit 12A Multivesicular body subunit 12B Polyubiquitin-B Polyubiquitin-C Tumor susceptibility gene 101 protein Ubiquitin-associated protein 1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Vacuolar protein sorting-associated protein 28 homolog Vacuolar protein sorting-associated protein 37A Vacuolar protein sorting-associated protein 37B Vacuolar protein sorting-associated protein 37C Vacuolar protein sorting-associated protein 37D	A5D8V6 O60551 P04591 P0CG47 P0CG48 P62979 P62987 Q86XT2 Q8NEZ2 Q96EY5 Q99816 Q9H7P6 Q9H9H4 Q9NZ09 Q9UK41	C9orf28 CFBP FAM125A FAM125B HCRP1 MVB12A MVB12B NMT2 PML39 RPS27A TSG101 UBA52 UBA80 UBAP1 UBB UBC UBCEP1 UBCEP2 VPS28 VPS37A VPS37B VPS37C VPS37D WBSCR24 gag
Ceramide signalling	Beta-nerve growth factor Sphingomyelin phosphodiesterase 2 Tumor necrosis factor receptor superfamily member 16	O60906 P01138 P08138	NGF NGFB NGFR SMPD2 TNFRSF16
RAB GEFs exchange GTP for GDP on RABs	14-3-3 protein epsilon ALS2 C-terminal-like protein Alsin Ankyrin repeat domain-containing protein 27 BLOC-3 complex member HPS1 BLOC-3 complex member HPS4 C-myc promoter-binding protein DENN domain-containing protein 1A DENN domain-containing protein 1B DENN domain-containing protein 1C DENN domain-containing protein 2A DENN domain-containing protein 2B DENN domain-containing protein 2C DENN domain-containing protein 2D DENN domain-containing protein 3 DENN domain-containing protein 4B DENN domain-containing protein 4C DENN domain-containing protein 5A DENN domain-containing protein 5B GTPase-activating protein and VPS9 domain-containing protein 1 Guanine nucleotide exchange factor for Rab-3A Guanine nucleotide exchange factor subunit RIC1 Myotubularin-related protein 13 Myotubularin-related protein 5 Protein DENND6A Protein DENND6B RAB6A-GEF complex partner protein 2 RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Rab GDP dissociation inhibitor alpha Rab GDP dissociation inhibitor beta Rab proteins geranylgeranyltransferase component A 1 Rab proteins geranylgeranyltransferase component A 2 Rab-3A-interacting protein Rab3 GTPase-activating protein catalytic subunit Rab3 GTPase-activating protein non-catalytic subunit Rab5 GDP/GTP exchange factor Ras and Rab interactor 1 Ras and Rab interactor 2 Ras and Rab interactor 3 Ras and Rab interactor-like protein Ras-related protein Rab-10 Ras-related protein Rab-12 Ras-related protein Rab-13 Ras-related protein Rab-14 Ras-related protein Rab-18 Ras-related protein Rab-1A Ras-related protein Rab-1B Ras-related protein Rab-21 Ras-related protein Rab-27A Ras-related protein Rab-27B Ras-related protein Rab-31 Ras-related protein Rab-32 Ras-related protein Rab-35 Ras-related protein Rab-38 Ras-related protein Rab-39A Ras-related protein Rab-39B Ras-related protein Rab-3A Ras-related protein Rab-5A Ras-related protein Rab-5B Ras-related protein Rab-5C Ras-related protein Rab-6A Ras-related protein Rab-6B Ras-related protein Rab-7a Ras-related protein Rab-7b Ras-related protein Rab-8A Ras-related protein Rab-8B Ras-related protein Rab-9A Ras-related protein Rab-9B Serine/threonine-protein kinase ULK1 Trafficking protein particle complex subunit 10 Trafficking protein particle complex subunit 11 Trafficking protein particle complex subunit 12 Trafficking protein particle complex subunit 13 Trafficking protein particle complex subunit 1 Trafficking protein particle complex subunit 2-like protein Trafficking protein particle complex subunit 2 Trafficking protein particle complex subunit 3 Trafficking protein particle complex subunit 4 Trafficking protein particle complex subunit 5 Trafficking protein particle complex subunit 6A Trafficking protein particle complex subunit 6B Trafficking protein particle complex subunit 8 Trafficking protein particle complex subunit 9 Vacuolar fusion protein CCZ1 homolog B Vacuolar fusion protein CCZ1 homolog Vacuolar fusion protein MON1 homolog A Vacuolar fusion protein MON1 homolog B	A2RUS2 A5PLN9 O00194 O43617 O75064 O75385 O75865 O95248 P0DI81 P20336 P20339 P20340 P24386 P26374 P31150 P31749 P31751 P48553 P50395 P51148 P51149 P51151 P51153 P51159 P57729 P61006 P61020 P61026 P61106 P62258 P62820 P78524 P86790 P86791 Q13636 Q13637 Q13671 Q14964 Q14C86 Q15042 Q15286 Q4ADV7 Q5VZ89 Q60I27 Q68D51 Q6IQ22 Q6IQ26 Q6P3S1 Q6ZS11 Q6ZUT9 Q7L1V2 Q7Z392 Q7Z401 Q86SZ2 Q86VX9 Q86WG5 Q8IUR0 Q8IV53 Q8IWF6 Q8NEG7 Q8TB24 Q8TBN0 Q8TEH3 Q8WVT3 Q8WYP3 Q92546 Q92902 Q92930 Q96AH8 Q96DA2 Q96NW4 Q96Q05 Q96Q42 Q96QF0 Q9H0U4 Q9H2M9 Q9H6A0 Q9NP72 Q9NP90 Q9NQG7 Q9NRW1 Q9UJ41 Q9UL25 Q9UL33 Q9ULE3 Q9Y243 Q9Y296 Q9Y2L5 Q9Y5R8	AKT1 AKT2 AKT3 ALS2 ALS2CL ALS2CR6 ANKRD27 BET3 BET5 C1orf218 C4orf41 C5orf44 C7orf28A C7orf28B C9orf55 C9orf55B CCZ1 CCZ1B CHM CHML CIP150 CMT4B2 DENND1A DENND1B DENND1C DENND2A DENND2B DENND2C DENND2D DENND3 DENND4A DENND4B DENND4C DENND5A DENND5B DENND6A DENND6B EHOC1 FAM116A FAM116B FAM31A FAM31B FAM31C GAPEX5 GAPVD1 GDI1 GDI2 GDIL HPS HPS1 HPS4 HSRG1 HTS1 IRLB KIAA0066 KIAA0118 KIAA0258 KIAA0476 KIAA0722 KIAA0839 KIAA0870 KIAA0872 KIAA1012 KIAA1091 KIAA1277 KIAA1432 KIAA1521 KIAA1563 KIAA1608 KIAA1667 KIAA1766 KIAA1882 MEL MON1A MON1B MTMR13 MTMR5 MUM2 MYCPBP NIBP OPHN2 PKB PKBG RAB1 RAB10 RAB12 RAB13 RAB14 RAB18 RAB1A RAB1B RAB1C RAB21 RAB22B RAB27 RAB27A RAB27B RAB31 RAB32 RAB35 RAB38 RAB39 RAB39A RAB39B RAB3A RAB3GAP RAB3GAP1 RAB3GAP2 RAB3IL1 RAB3IP RAB5 RAB5A RAB5B RAB5C RAB6 RAB6A RAB6B RAB6IP1 RAB7 RAB7A RAB7B RAB8 RAB8A RAB8B RAB9 RAB9A RAB9B RAB9L RABEX5 RABGDIA RABGDIB RABGEF1 RABIN8 RABL RAC RAP6 RASSF4 RAY REP1 REP2 RGP1 RIC1 RIN1 RIN2 RIN3 RINL SAND1 SAND2 SBDN SBF1 SBF2 SEDL ST5 TCD TMEM1 TRAMM TRAPPC1 TRAPPC10 TRAPPC11 TRAPPC12 TRAPPC13 TRAPPC2 TRAPPC2L TRAPPC3 TRAPPC4 TRAPPC5 TRAPPC6A TRAPPC6B TRAPPC8 TRAPPC9 TTC15 ULK1 XAP4 YWHAE
Post-chaperonin tubulin folding pathway	ADP-ribosylation factor-like protein 2 Putative tubulin-like protein alpha-4B Tubulin alpha chain-like 3 Tubulin alpha-1A chain Tubulin alpha-1B chain Tubulin alpha-1C chain Tubulin alpha-3C chain Tubulin alpha-3D chain Tubulin alpha-3E chain Tubulin alpha-4A chain Tubulin alpha-8 chain Tubulin beta-1 chain Tubulin beta-2A chain Tubulin beta-2B chain Tubulin beta-3 chain Tubulin beta-4A chain Tubulin beta-4B chain Tubulin beta-6 chain Tubulin-folding cofactor B Tubulin-specific chaperone A Tubulin-specific chaperone C Tubulin-specific chaperone D Tubulin-specific chaperone E	A6NHL2 O75347 P04350 P0DPH7 P0DPH8 P36404 P68363 P68366 P68371 Q13509 Q13885 Q15813 Q15814 Q6PEY2 Q71U36 Q99426 Q9BQE3 Q9BTW9 Q9BUF5 Q9BVA1 Q9H4B7 Q9H853 Q9NY65	ARL2 CG22 CKAP1 KIAA0988 SSD1 TBCA TBCB TBCC TBCD TBCE TFCD TUBA1 TUBA1A TUBA1B TUBA1C TUBA2 TUBA3 TUBA3C TUBA3D TUBA3E TUBA4 TUBA4A TUBA4B TUBA6 TUBA8 TUBAL2 TUBAL3 TUBB1 TUBB2 TUBB2A TUBB2B TUBB2C TUBB3 TUBB4 TUBB4A TUBB4B TUBB5 TUBB6
XAV939 stabilizes AXIN	Poly [ADP-ribose] polymerase tankyrase-1 Poly [ADP-ribose] polymerase tankyrase-2	O95271 Q9H2K2	PARP5A PARP5B PARPL TANK2 TIN1 TINF1 TNKL TNKS TNKS1 TNKS2
Antigen Presentation: Folding, assembly and peptide loading of class I MHC	Antigen peptide transporter 1 Antigen peptide transporter 2 Beclin 1-associated autophagy-related key regulator Beclin-1 Beta-2-microglobulin Calnexin Calreticulin Endoplasmic reticulum aminopeptidase 1 Endoplasmic reticulum aminopeptidase 2 Endoplasmic reticulum chaperone BiP HLA class I histocompatibility antigen, A alpha chain HLA class I histocompatibility antigen, B alpha chain HLA class I histocompatibility antigen, C alpha chain HLA class I histocompatibility antigen, alpha chain E HLA class I histocompatibility antigen, alpha chain F HLA class I histocompatibility antigen, alpha chain G ORF8 protein Phosphatidylinositol 3-kinase catalytic subunit type 3 Phosphoinositide 3-kinase regulatory subunit 4 Protein SEC13 homolog Protein disulfide-isomerase A3 Protein transport protein Sec23A Protein transport protein Sec24A Protein transport protein Sec24B Protein transport protein Sec24C Protein transport protein Sec24D Protein transport protein Sec31A Putative HLA class I histocompatibility antigen, alpha chain H Small COPII coat GTPase SAR1B Tapasin	O15533 O94855 O94979 O95486 O95487 P01889 P01893 P04439 P0DTC8 P10321 P11021 P13747 P17693 P27797 P27824 P30101 P30511 P53992 P55735 P61769 Q03518 Q03519 Q14457 Q15436 Q6P179 Q6ZNE5 Q8NEB9 Q99570 Q9NZ08 Q9Y6B6	8 ABCB2 ABCB3 APPILS ARTS1 ATG14 ATG14L B2M BECN1 CALR CANX CRTC D3S1231E ERAP1 ERAP2 ERP57 ERP60 GRP58 GRP78 GT197 HLA-5.4 HLA-6.0 HLA-6.2 HLA-A HLA-B HLA-C HLA-E HLA-F HLA-G HLA-H HLAA HLAB HLAC HLAE HLAF HLAG HLAH HSPA5 KIAA0079 KIAA0525 KIAA0755 KIAA0831 KIAA0905 LRAP NGS17 PDIA3 PIK3C3 PIK3R4 PSF1 PSF2 RING11 RING4 SAR1B SARA2 SARB SEC13 SEC13A SEC13L1 SEC13R SEC23A SEC24A SEC24B SEC24C SEC24D SEC31A SEC31L1 TAP1 TAP2 TAPA TAPBP VPS15 VPS34 Y1 Y3
Defective SLC39A4 causes acrodermatitis enteropathica, zinc-deficiency type (AEZ)	Zinc transporter ZIP4	Q6P5W5	SLC39A4 ZIP4
Generation of second messenger molecules	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 Actin nucleation-promoting factor WAS Ena/VASP-like protein FYN-binding protein 1 GRB2-related adapter protein 2 HLA class II histocompatibility antigen, DP alpha 1 chain HLA class II histocompatibility antigen, DP beta 1 chain HLA class II histocompatibility antigen, DQ alpha 1 chain HLA class II histocompatibility antigen, DQ alpha 2 chain HLA class II histocompatibility antigen, DQ beta 1 chain HLA class II histocompatibility antigen, DQ beta 2 chain HLA class II histocompatibility antigen, DR alpha chain HLA class II histocompatibility antigen, DR beta 3 chain HLA class II histocompatibility antigen, DR beta 4 chain HLA class II histocompatibility antigen, DR beta 5 chain HLA class II histocompatibility antigen, DRB1 beta chain Immunoglobulin superfamily member 2 Linker for activation of T-cells family member 1 Lymphocyte cytosolic protein 2 Protein enabled homolog SH2/SH3 adapter protein NCK1 Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 2 Serine/threonine-protein kinase PAK 3 T cell receptor alpha chain constant T cell receptor alpha variable 19 T cell receptor alpha variable 29/delta variable 5 T cell receptor alpha variable 8-4 T cell receptor beta constant 1 T cell receptor beta variable 12-3 T cell receptor beta variable 7-9 T-cell surface glycoprotein CD3 delta chain T-cell surface glycoprotein CD3 epsilon chain T-cell surface glycoprotein CD3 gamma chain T-cell surface glycoprotein CD4 Tyrosine-protein kinase ITK/TSK Tyrosine-protein kinase Lck Tyrosine-protein kinase ZAP-70 Vasodilator-stimulated phosphoprotein	A0A0A6YYK7 O15117 O43561 O75791 O75914 P01730 P01733 P01737 P01848 P01850 P01903 P01906 P01909 P01911 P01920 P04234 P04435 P04437 P04440 P05538 P06239 P07766 P09693 P13762 P16333 P16885 P19174 P20036 P42768 P43403 P50552 P79483 Q08881 Q13094 Q13153 Q13177 Q30154 Q8N8S7 Q93033 Q9UI08	CD101 CD3D CD3E CD3G CD4 EMT ENAH EVL EWI101 FYB FYB1 GADS GRAP2 GRB2L GRID HLA-DP1A HLA-DP1B HLA-DPA1 HLA-DPB1 HLA-DQA1 HLA-DQA2 HLA-DQB HLA-DQB1 HLA-DQB2 HLA-DRA HLA-DRA1 HLA-DRB1 HLA-DRB3 HLA-DRB4 HLA-DRB5 HLA-DXA HLA-DXB HLASB IGSF2 IMD2 ITK LAT LCK LCP2 LYK MENA NCK NCK1 OPHN3 PAK1 PAK2 PAK3 PLC1 PLCG1 PLCG2 RNB6 SLAP130 SRK T3D T3E T3G TCRA TCRBV12S3 TCRBV8S1 TRAC TRAV19 TRAV29DV5 TRAV8-4 TRBC1 TRBV12-3 TRBV7-9 V7 VASP WAS ZAP70
Resolution of D-loop Structures through Holliday Junction Intermediates	26S proteasome complex subunit SEM1 BRCA1-associated RING domain protein 1 Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN Breast cancer type 1 susceptibility protein Breast cancer type 2 susceptibility protein Crossover junction endonuclease EME1 Crossover junction endonuclease MUS81 DNA endonuclease RBBP8 DNA repair protein RAD50 DNA repair protein RAD51 homolog 1 DNA repair protein RAD51 homolog 2 DNA repair protein RAD51 homolog 3 DNA repair protein RAD51 homolog 4 DNA repair protein XRCC2 DNA repair protein XRCC3 DNA repair-scaffolding protein DNA replication ATP-dependent helicase/nuclease DNA2 DNA topoisomerase 3-alpha Double-strand break repair protein MRE11 Exonuclease 1 FIGNL1-interacting regulator of recombination and mitosis Fanconi anemia group J protein Fidgetin-like protein 1 Flap endonuclease GEN homolog 1 Histone acetyltransferase KAT5 Nibrin Partner and localizer of BRCA2 Probable crossover junction endonuclease EME2 RAD51-associated protein 1 RecQ-like DNA helicase BLM RecQ-mediated genome instability protein 1 RecQ-mediated genome instability protein 2 Serine-protein kinase ATM Structure-specific endonuclease subunit SLX1 Structure-specific endonuclease subunit SLX4	A4GXA9 O15315 O43502 O43542 O43543 O60934 O75771 P38398 P49959 P51530 P51587 P54132 P60896 Q06609 Q13315 Q13472 Q14159 Q14191 Q17RS7 Q6PIW4 Q86YC2 Q8IY92 Q92878 Q92993 Q96AY2 Q96B01 Q96E14 Q96NY9 Q99708 Q99728 Q9BQ83 Q9BX63 Q9H9A7 Q9NSG2 Q9UQ84	APOLO1 ATM BACH1 BARD1 BLM BRCA1 BRCA2 BRIP1 BTBD12 C16orf75 C1orf112 C7orf76 C9orf76 CTIP DNA2 DNA2L DSS1 EME1 EME2 EXO1 EXOI FACD FANCD1 FANCJ FANCN FIGNL1 FIRRM GEN1 GIYD1 GIYD2 HEX1 HNGS1 HTATIP KAT5 KIAA0083 KIAA0146 KIAA1784 KIAA1987 MMS4 MRE11 MRE11A MUS81 NBN NBS NBS1 P95 PALB2 PIR51 RAD50 RAD51 RAD51A RAD51AP1 RAD51B RAD51C RAD51D RAD51L1 RAD51L2 RAD51L3 RBBP8 REC2 RECA RECQ2 RECQ3 RECQL2 RECQL3 RMI1 RMI2 RNF53 SEM1 SHFDG1 SHFM1 SLX1 SLX1A SLX1B SLX4 SPIDR TIP60 TOP3 TOP3A WRN XRCC2 XRCC3
Interferon alpha/beta signaling	2'-5'-oligoadenylate synthase 1 2'-5'-oligoadenylate synthase 2 2'-5'-oligoadenylate synthase 3 2'-5'-oligoadenylate synthase-like protein 2-5A-dependent ribonuclease ATP-binding cassette sub-family E member 1 Bone marrow stromal antigen 2 Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 Double-stranded RNA-specific adenosine deaminase Early growth response protein 1 Guanylate-binding protein 2 HLA class I histocompatibility antigen, A alpha chain HLA class I histocompatibility antigen, B alpha chain HLA class I histocompatibility antigen, C alpha chain HLA class I histocompatibility antigen, alpha chain E HLA class I histocompatibility antigen, alpha chain F HLA class I histocompatibility antigen, alpha chain G Importin subunit alpha-5 Importin subunit beta-1 Inositol hexakisphosphate kinase 2 Interferon alpha-1/13 Interferon alpha-10 Interferon alpha-14 Interferon alpha-16 Interferon alpha-17 Interferon alpha-21 Interferon alpha-2 Interferon alpha-4 Interferon alpha-5 Interferon alpha-6 Interferon alpha-7 Interferon alpha-8 Interferon alpha-inducible protein 27, mitochondrial Interferon alpha-inducible protein 6 Interferon alpha/beta receptor 1 Interferon beta Interferon regulatory factor 1 Interferon regulatory factor 2 Interferon regulatory factor 3 Interferon regulatory factor 4 Interferon regulatory factor 5 Interferon regulatory factor 6 Interferon regulatory factor 7 Interferon regulatory factor 8 Interferon regulatory factor 9 Interferon-induced 35 kDa protein Interferon-induced GTP-binding protein Mx1 Interferon-induced GTP-binding protein Mx2 Interferon-induced protein with tetratricopeptide repeats 1 Interferon-induced protein with tetratricopeptide repeats 2 Interferon-induced protein with tetratricopeptide repeats 3 Interferon-induced protein with tetratricopeptide repeats 5 Interferon-induced transmembrane protein 1 Interferon-induced transmembrane protein 2 Interferon-induced transmembrane protein 3 Interferon-induced, double-stranded RNA-activated protein kinase Interferon-stimulated gene 20 kDa protein Non-receptor tyrosine-protein kinase TYK2 Nucleoprotein Polyubiquitin-B Polyubiquitin-C Proteasome subunit beta type-8 Putative HLA class I histocompatibility antigen, alpha chain H S-adenosylmethionine-dependent nucleotide dehydratase RSAD2 Signal transducer and activator of transcription 1-alpha/beta Signal transducer and activator of transcription 2 Suppressor of cytokine signaling 1 Suppressor of cytokine signaling 3 Tyrosine-protein kinase JAK1 Tyrosine-protein phosphatase non-receptor type 11 Tyrosine-protein phosphatase non-receptor type 6 Ubiquitin-like protein ISG15 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein XIAP-associated factor 1	O14543 O14879 O14896 O15524 P00973 P01562 P01563 P01566 P01567 P01568 P01569 P01570 P01571 P01574 P01889 P01893 P04439 P05013 P05014 P05015 P05161 P09912 P09913 P09914 P0CG47 P0CG48 P0DTC9 P10321 P10914 P13164 P13747 P14316 P17181 P17693 P18146 P19525 P20591 P20592 P23458 P28062 P29350 P29597 P29728 P30511 P32456 P32881 P40305 P42224 P52294 P52630 P55265 P61221 P62979 P62987 P80217 Q00978 Q01628 Q01629 Q02556 Q05823 Q06124 Q10589 Q13325 Q13568 Q14653 Q14974 Q15306 Q15646 Q6GPH4 Q8WXG1 Q92985 Q96AZ6 Q9UHH9 Q9Y3Z3 Q9Y6K5	ABCE1 ADAR ADAR1 BIRC4BP BST2 CD225 CIG-42 CIG-49 CIG5 CIS3 DSRAD EGR1 EIF2AK2 G10P1 G10P2 G1P1 G1P2 G1P3 GBP2 HCP HEM45 HLA-5.4 HLA-6.0 HLA-6.2 HLA-A HLA-B HLA-C HLA-E HLA-F HLA-G HLA-H HLAA HLAB HLAC HLAE HLAF HLAG HLAH ICSBP1 IFB IFI17 IFI27 IFI35 IFI4 IFI54 IFI56 IFI6 IFI60 IFIT1 IFIT2 IFIT3 IFIT4 IFIT5 IFITM1 IFITM2 IFITM3 IFNA1 IFNA10 IFNA13 IFNA14 IFNA16 IFNA17 IFNA2 IFNA21 IFNA2A IFNA2B IFNA2C IFNA4 IFNA5 IFNA6 IFNA7 IFNA8 IFNAI1 IFNAR IFNAR1 IFNB IFNB1 IFP35 IHPK2 IP6K2 IRF1 IRF2 IRF3 IRF4 IRF5 IRF6 IRF7 IRF8 IRF9 ISG15 ISG20 ISG54 ISG56 ISG58 ISG60 ISGF3G JAK1 JAK1A JAK1B KPNA1 KPNB1 KROX24 LMP7 MOP5 MUM1 MX1 MX2 N NTF97 OAS1 OAS2 OAS3 OASL OIAS PKR PRKR PSMB5i PSMB8 PTP1C PTP2C PTPN11 PTPN6 RCH2 RI58 RING10 RLI RNASEL RNASEL1 RNASELI RNS4 RNS4I RPS27A RSAD2 SAMHD1 SHPTP2 SOCS1 SOCS3 SSI1 SSI3 STAT1 STAT2 TIP3 TRIP14 TYK2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 UCRP XAF1 XIAPAF1 Y2 ZNF225
Ubiquitin-dependent degradation of Cyclin D	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Cyclin-dependent kinase 4 G1/S-specific cyclin-D1 Glycogen synthase kinase-3 beta Polyubiquitin-B Polyubiquitin-C Proteasomal ubiquitin receptor ADRM1 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00231 O00232 O00487 O14818 O43242 P0CG47 P0CG48 P11802 P17980 P20618 P24385 P25786 P25787 P25788 P25789 P28066 P28070 P28072 P28074 P35998 P43686 P48556 P49720 P49721 P49841 P51665 P60896 P60900 P62191 P62195 P62333 P62979 P62987 Q13200 Q15008 Q16186 Q99436 Q99460 Q9UNM6	ADRM1 BCL1 C7orf76 CCND1 CDK4 DSS1 GP110 GSK3B HC2 HC3 HC8 HC9 HSPC KIAA0107 LMPX LMPY MB1 MIP224 MOV34L MSS1 NU PFAAP4 POH1 PRAD1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PSMD8 RPS27A SEM1 SHFDG1 SHFM1 SUG1 SUG2 TBP1 TBP7 TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 X Y Z
SLIT2:ROBO1 increases RHOA activity	Roundabout homolog 1 Slit homolog 2 protein Transforming protein RhoA Unconventional myosin-IXb	O94813 P61586 Q13459 Q9Y6N7	ARH12 ARHA DUTT1 MYO9B MYR5 RHO12 RHOA ROBO1 SLIL3 SLIT2
DEx/H-box helicases activate type I IFN and inflammatory cytokines production	ATP-dependent DNA/RNA helicase DHX36 ATP-dependent RNA helicase A Interferon regulatory factor 7 Myeloid differentiation primary response protein MyD88 Nuclear factor NF-kappa-B p100 subunit Nuclear factor NF-kappa-B p105 subunit Transcription factor p65	P19838 Q00653 Q04206 Q08211 Q92985 Q99836 Q9H2U1	DDX36 DDX9 DHX36 DHX9 IRF7 KIAA1488 LKP LYT10 MLEL1 MYD88 NDH2 NFKB1 NFKB2 NFKB3 RELA RHAU
CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde	Calcium/calmodulin-dependent protein kinase kinase 1 Calcium/calmodulin-dependent protein kinase kinase 2 Calcium/calmodulin-dependent protein kinase type II subunit beta Calcium/calmodulin-dependent protein kinase type II subunit gamma Calcium/calmodulin-dependent protein kinase type IV Calmodulin-1 Importin subunit alpha-1	P0DP23 P52292 Q13554 Q13555 Q16566 Q8N5S9 Q96RR4	CALM CALM1 CAM CAM1 CAM2 CAMK CAMK-GR CAMK-II CAMK2 CAMK2B CAMK2G CAMK4 CAMKB CAMKG CAMKIV CAMKK1 CAMKK2 CAMKKA CAMKKB KIAA0787 KPNA2 RCH1 SRP1
NF-kB is activated and signals survival	Beta-nerve growth factor Inhibitor of nuclear factor kappa-B kinase subunit beta Interleukin-1 receptor-associated kinase 1 NF-kappa-B inhibitor alpha Nuclear factor NF-kappa-B p105 subunit Polyubiquitin-B Polyubiquitin-C Sequestosome-1 TNF receptor-associated factor 6 Transcription factor p65 Tumor necrosis factor receptor superfamily member 16 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O14920 P01138 P08138 P0CG47 P0CG48 P19838 P25963 P51617 P62979 P62987 Q04206 Q13501 Q9Y4K3	IKBA IKBKB IKKB IRAK IRAK1 MAD3 NFKB1 NFKB3 NFKBI NFKBIA NGF NGFB NGFR ORCA OSIL RELA RNF85 RPS27A SQSTM1 TNFRSF16 TRAF6 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2
Platelet sensitization by LDL	Apolipoprotein B-100 Cytosolic phospholipase A2 Low-density lipoprotein receptor-related protein 8 Mitogen-activated protein kinase 14 Platelet endothelial cell adhesion molecule Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform Tyrosine-protein kinase Fgr Tyrosine-protein phosphatase non-receptor type 11 Tyrosine-protein phosphatase non-receptor type 6	P04114 P09769 P16284 P29350 P30153 P30154 P47712 P62714 P67775 Q06124 Q13362 Q14114 Q14738 Q15172 Q15173 Q16537 Q16539	APOB APOER2 CPLA2 CSBP CSBP1 CSBP2 CSPB1 FGR HCP KIAA0044 LRP8 MAPK14 MXI2 PECAM1 PLA2G4 PLA2G4A PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E PTP1C PTP2C PTPN11 PTPN6 SAPK2A SHPTP2 SRC2
RNA Polymerase II HIV Promoter Escape	CDK-activating kinase assembly factor MAT1 Cyclin-H Cyclin-dependent kinase 7 DNA-directed RNA polymerase II subunit RPB11-a DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 General transcription and DNA repair factor IIH helicase subunit XPD General transcription and DNA repair factor IIH helicase/translocase subunit XPB General transcription factor IIE subunit 1 General transcription factor IIF subunit 1 General transcription factor IIF subunit 2 General transcription factor IIH subunit 1 General transcription factor IIH subunit 2 General transcription factor IIH subunit 3 General transcription factor IIH subunit 4 General transcription factor IIH subunit 5 TATA-binding protein-associated factor 2N TATA-box-binding protein Transcription initiation factor IIA subunit 1 Transcription initiation factor IIA subunit 2 Transcription initiation factor IIB Transcription initiation factor IIE subunit beta Transcription initiation factor TFIID subunit 1-like Transcription initiation factor TFIID subunit 10 Transcription initiation factor TFIID subunit 11 Transcription initiation factor TFIID subunit 12 Transcription initiation factor TFIID subunit 13 Transcription initiation factor TFIID subunit 1 Transcription initiation factor TFIID subunit 2 Transcription initiation factor TFIID subunit 3 Transcription initiation factor TFIID subunit 4 Transcription initiation factor TFIID subunit 4B Transcription initiation factor TFIID subunit 5 Transcription initiation factor TFIID subunit 6 Transcription initiation factor TFIID subunit 7-like Transcription initiation factor TFIID subunit 7 Transcription initiation factor TFIID subunit 9 Transcription initiation factor TFIID subunit 9B	O00268 O15514 P13984 P18074 P19387 P19388 P19447 P20226 P21675 P24928 P29083 P29084 P30876 P32780 P35269 P36954 P49848 P50613 P51946 P51948 P52434 P52435 P52655 P52657 P53803 P61218 P62487 P62875 Q00403 Q12962 Q13888 Q13889 Q15542 Q15543 Q15544 Q15545 Q16514 Q16594 Q5H9L4 Q5VWG9 Q6P1X5 Q6ZYL4 Q8IZX4 Q92750 Q92759 Q92804 Q9HBM6	BA2R BTF2 BTF2P44 C6orf175 CAK CAK1 CAP35 CCG1 CCGS CCNH CDK7 CDKN7 CIF150 ERCC2 ERCC3 GTF2A1 GTF2A2 GTF2B GTF2D1 GTF2E1 GTF2E2 GTF2F1 GTF2F2 GTF2H1 GTF2H2 GTF2H3 GTF2H4 GTF2H5 MAT1 MNAT1 MO15 POLR2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J1 POLR2K POLR2L POLRF RAP30 RAP74 RBP56 RNF66 RPB7 STK1 TAF1 TAF10 TAF11 TAF12 TAF13 TAF15 TAF1L TAF2 TAF2A TAF2B TAF2C TAF2C1 TAF2C2 TAF2D TAF2E TAF2F TAF2G TAF2H TAF2I TAF2J TAF2K TAF2N TAF2Q TAF3 TAF4 TAF4A TAF4B TAF5 TAF6 TAF7 TAF7L TAF9 TAF9B TAF9L TAFII105 TAFII130 TAFII135 TAFII18 TAFII20 TAFII30 TAFII31 TAFII55 TAFII70 TBP TF2A1 TF2A2 TF2B TF2D TF2E1 TF2E2 TFIIB TFIID TTDA XPB XPBC XPD XPDC

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