GlyCosmos Portal

Homo sapiens (human)

Summary

Taxonomy ID: 9606
PubChem Taxonomy: 9606

Genes (10109) Glycans (5831) Glycoproteins (15837) Lectins (297) Pathways (2074)

Displaying entries **1826 - 1850** of **2074** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol
Interleukin-2 family signaling	Galectin-9 Hepatitis A virus cellular receptor 2	O00182 Q8TDQ0	HAVCR2 LGALS9 TIM3 TIMD3
Assembly of the pre-replicative complex	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Anaphase-promoting complex subunit 10 Anaphase-promoting complex subunit 11 Anaphase-promoting complex subunit 15 Anaphase-promoting complex subunit 16 Anaphase-promoting complex subunit 1 Anaphase-promoting complex subunit 2 Anaphase-promoting complex subunit 4 Anaphase-promoting complex subunit 5 Anaphase-promoting complex subunit 7 Anaphase-promoting complex subunit CDC26 Cell division control protein 6 homolog Cell division cycle protein 16 homolog Cell division cycle protein 23 homolog Cell division cycle protein 27 homolog DNA replication factor Cdt1 DNA replication licensing factor MCM2 DNA replication licensing factor MCM3 DNA replication licensing factor MCM4 DNA replication licensing factor MCM5 DNA replication licensing factor MCM6 DNA replication licensing factor MCM7 Fizzy-related protein homolog Geminin Origin recognition complex subunit 1 Origin recognition complex subunit 2 Origin recognition complex subunit 3 Origin recognition complex subunit 4 Origin recognition complex subunit 5 Origin recognition complex subunit 6 Polyubiquitin-B Polyubiquitin-C Proteasomal ubiquitin receptor ADRM1 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Ubiquitin-conjugating enzyme E2 C Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 E1 Ubiquitin-conjugating enzyme E2 S Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00231 O00232 O00487 O00762 O14818 O43242 O43913 O43929 O75496 P0CG47 P0CG48 P17980 P20618 P25205 P25786 P25787 P25788 P25789 P28066 P28070 P28072 P28074 P30260 P33991 P33992 P33993 P35998 P43686 P48556 P49720 P49721 P49736 P51665 P51668 P51965 P60006 P60896 P60900 P62191 P62195 P62333 P62979 P62987 Q13042 Q13200 Q13415 Q13416 Q14566 Q15008 Q16186 Q16763 Q8NHZ8 Q96DE5 Q99436 Q99460 Q99741 Q9H1A4 Q9H211 Q9NYG5 Q9UBD5 Q9UJX2 Q9UJX3 Q9UJX4 Q9UJX5 Q9UJX6 Q9UM11 Q9UM13 Q9UNM6 Q9Y5N6	ADRM1 ANAPC1 ANAPC10 ANAPC11 ANAPC12 ANAPC15 ANAPC16 ANAPC2 ANAPC3 ANAPC4 ANAPC5 ANAPC6 ANAPC7 ANAPC8 APC10 APC2 APC4 APC5 APC7 BM28 C10orf104 C11orf51 C7orf76 C9orf17 CCNL1 CDC16 CDC18L CDC21 CDC23 CDC26 CDC27 CDC46 CDC47 CDC6 CDCL1 CDH1 CDT1 CENP-27 D0S1430E D17S978E DSS1 E2EPF FYR FZR FZR1 GMNN GP110 HC2 HC3 HC8 HC9 HSPC KIAA0030 KIAA0107 KIAA1242 KIAA1406 LATHEO LMPX LMPY MB1 MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 MIP224 MOV34L MSS1 NU ORC1 ORC1L ORC2 ORC2L ORC3 ORC3L ORC4 ORC4L ORC5 ORC5L ORC6 ORC6L PARC1 PFAAP4 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PSMD8 RPS27A SEM1 SFT SHFDG1 SHFM1 SUG1 SUG2 TBP1 TBP7 TRAP2 TSG24 UBA52 UBA80 UBB UBC UBC5A UBCEP1 UBCEP2 UBCH10 UBCH5 UBCH5A UBCH6 UBE2C UBE2D1 UBE2E1 UBE2S X Y Z
Interaction between L1 and Ankyrins	Ankyrin-1 Ankyrin-2 Ankyrin-3 Neural cell adhesion molecule L1 Neurofascin Neuronal cell adhesion molecule Potassium voltage-gated channel subfamily KQT member 2 Potassium voltage-gated channel subfamily KQT member 3 Sodium channel protein type 1 subunit alpha Sodium channel protein type 10 subunit alpha Sodium channel protein type 11 subunit alpha Sodium channel protein type 2 subunit alpha Sodium channel protein type 3 subunit alpha Sodium channel protein type 4 subunit alpha Sodium channel protein type 5 subunit alpha Sodium channel protein type 7 subunit alpha Sodium channel protein type 8 subunit alpha Sodium channel protein type 9 subunit alpha Sodium channel regulatory subunit beta-1 Sodium channel regulatory subunit beta-2 Sodium channel regulatory subunit beta-3 Sodium channel subunit beta-4 Spectrin alpha chain, erythrocytic 1 Spectrin alpha chain, non-erythrocytic 1 Spectrin beta chain, erythrocytic Spectrin beta chain, non-erythrocytic 1 Spectrin beta chain, non-erythrocytic 2 Spectrin beta chain, non-erythrocytic 4 Spectrin beta chain, non-erythrocytic 5	O15020 O43525 O43526 O60939 O94856 P02549 P11277 P16157 P32004 P35498 P35499 Q01082 Q01118 Q01484 Q07699 Q12955 Q13813 Q14524 Q15858 Q8IWT1 Q92823 Q99250 Q9H254 Q9NRC6 Q9NY46 Q9NY72 Q9UI33 Q9UQD0 Q9Y5Y9	ANK ANK1 ANK2 ANK3 ANKB BSPECV CAML1 HBA HUBSPECV HUSPECV KCNQ2 KCNQ3 KIAA0302 KIAA0343 KIAA0756 KIAA1158 KIAA1356 KIAA1642 L1CAM MED MIC5 NAC1 NAC2 NAC3 NEAS NENA NFASC NRCAM SCA5 SCN1 SCN10A SCN11A SCN12A SCN1A SCN1B SCN2A SCN2A1 SCN2A2 SCN2B SCN3A SCN3B SCN4A SCN4B SCN5A SCN6A SCN7A SCN8A SCN9A SNS2 SPTA SPTA1 SPTA2 SPTAN1 SPTB SPTB1 SPTB2 SPTBN1 SPTBN2 SPTBN3 SPTBN4 SPTBN5
Voltage gated Potassium channels	A-type voltage-gated potassium channel KCND1 A-type voltage-gated potassium channel KCND2 A-type voltage-gated potassium channel KCND3 Potassium voltage-gated channel subfamily A member 10 Potassium voltage-gated channel subfamily A member 1 Potassium voltage-gated channel subfamily A member 2 Potassium voltage-gated channel subfamily A member 3 Potassium voltage-gated channel subfamily A member 4 Potassium voltage-gated channel subfamily A member 5 Potassium voltage-gated channel subfamily A member 6 Potassium voltage-gated channel subfamily A member 7 Potassium voltage-gated channel subfamily B member 1 Potassium voltage-gated channel subfamily B member 2 Potassium voltage-gated channel subfamily KQT member 1 Potassium voltage-gated channel subfamily KQT member 2 Potassium voltage-gated channel subfamily KQT member 3 Potassium voltage-gated channel subfamily KQT member 4 Potassium voltage-gated channel subfamily KQT member 5 Potassium voltage-gated channel subfamily S member 1 Potassium voltage-gated channel subfamily S member 2 Potassium voltage-gated channel subfamily S member 3 Potassium voltage-gated channel subfamily V member 1 Potassium voltage-gated channel subfamily V member 2 Voltage-gated delayed rectifier potassium channel KCNH1 Voltage-gated delayed rectifier potassium channel KCNH4 Voltage-gated delayed rectifier potassium channel KCNH5 Voltage-gated delayed rectifier potassium channel KCNH8 Voltage-gated inwardly rectifying potassium channel KCNH2 Voltage-gated inwardly rectifying potassium channel KCNH3 Voltage-gated inwardly rectifying potassium channel KCNH6 Voltage-gated inwardly rectifying potassium channel KCNH7 Voltage-gated potassium channel KCNC1 Voltage-gated potassium channel KCNC2 Voltage-gated potassium channel KCNC3 Voltage-gated potassium channel KCNC4 Voltage-gated potassium channel regulatory subunit KCNF1 Voltage-gated potassium channel regulatory subunit KCNG1 Voltage-gated potassium channel regulatory subunit KCNG2 Voltage-gated potassium channel regulatory subunit KCNG3 Voltage-gated potassium channel regulatory subunit KCNG4 Voltage-gated potassium channel subunit beta-1 Voltage-gated potassium channel subunit beta-2 Voltage-gated potassium channel subunit beta-3	O43448 O43525 O43526 O95259 P16389 P17658 P22001 P22459 P22460 P48547 P51787 P56696 Q03721 Q09470 Q12809 Q13303 Q14003 Q14721 Q14722 Q16322 Q6PIU1 Q8NCM2 Q8TAE7 Q8TDN1 Q8TDN2 Q92953 Q96KK3 Q96L42 Q96PR1 Q96RP8 Q9BQ31 Q9H252 Q9H3M0 Q9NR82 Q9NS40 Q9NSA2 Q9NZV8 Q9UIX4 Q9UJ96 Q9UK17 Q9ULD8 Q9ULS6 Q9UQ05	C1orf30 EAG EAG1 EAG2 ERG ERG1 ERG2 ERG3 HERG HGK5 KCNA1 KCNA10 KCNA1B KCNA2 KCNA2B KCNA3 KCNA3B KCNA4 KCNA4L KCNA5 KCNA6 KCNA7 KCNA8 KCNA9 KCNAB1 KCNAB2 KCNAB3 KCNB1 KCNB2 KCNC1 KCNC2 KCNC3 KCNC4 KCND1 KCND2 KCND3 KCNF1 KCNF2 KCNG1 KCNG2 KCNG3 KCNG4 KCNH1 KCNH2 KCNH3 KCNH4 KCNH5 KCNH6 KCNH7 KCNH8 KCNK2 KCNQ1 KCNQ2 KCNQ3 KCNQ4 KCNQ5 KCNS1 KCNS2 KCNS3 KCNV1 KCNV2 KIAA1044 KIAA1144 KIAA1282 KVLQT1
Branched-chain amino acid catabolism	2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial 3-hydroxyacyl-CoA dehydrogenase type-2 3-hydroxyisobutyrate dehydrogenase, mitochondrial 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial Acetyl-CoA acetyltransferase, mitochondrial Branched-chain alpha-ketoacid dehydrogenase kinase Branched-chain-amino-acid aminotransferase, cytosolic Branched-chain-amino-acid aminotransferase, mitochondrial Dihydrolipoyl dehydrogenase, mitochondrial Enoyl-CoA hydratase, mitochondrial Isobutyryl-CoA dehydrogenase, mitochondrial Isovaleryl-CoA dehydrogenase, mitochondrial Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial Methylglutaconyl-CoA hydratase, mitochondrial Methylmalonate-semialdehyde/malonate-semialdehyde dehydrogenase [acylating], mitochondrial Protein phosphatase Mn(2+)-dependent 1K Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial Solute carrier family 25 member 44	O14874 O15382 P09622 P11182 P12694 P21953 P24752 P26440 P30084 P31937 P45954 P54687 Q02252 Q13825 Q6NVY1 Q8N3J5 Q96H78 Q96RQ3 Q99714 Q9HCC0 Q9UKU7	ACAD8 ACADSB ACAT ACAT1 ALDH6A1 ARC42 AUH BCAT1 BCAT2 BCATE2 BCATM BCKDHA BCKDHB BCKDHE2 BCKDK BCT1 BCT2 DBT DLD ECA39 ECA40 ECHS1 ERAB GCSL HADH2 HIBADH HIBCH HSD17B10 IBD IVD KIAA0446 LAD MAT MCCA MCCB MCCC1 MCCC2 MMSDH MRPP2 PHE3 PP2CM PPM1K SCHAD SDR5C1 SLC25A44 XH98G2
p130Cas linkage to MAPK signaling for integrins	Adapter molecule crk Amyloid beta A4 precursor protein-binding family B member 1-interacting protein Breast cancer anti-estrogen resistance protein 1 Fibrinogen alpha chain Fibrinogen beta chain Fibrinogen gamma chain Fibronectin Focal adhesion kinase 1 Integrin alpha-IIb Integrin beta-3 Proto-oncogene tyrosine-protein kinase Src Ras-related protein Rap-1A Ras-related protein Rap-1b Talin-1 von Willebrand factor	P02671 P02675 P02679 P02751 P04275 P05106 P08514 P12931 P46108 P56945 P61224 P62834 Q05397 Q7Z5R6 Q9Y490	APBB1IP BCAR1 CAS CASS1 CRK CRKAS F8VWF FAK FAK1 FGA FGB FGG FN FN1 GP2B GP3A ITGA2B ITGAB ITGB3 KIAA1027 KREV1 PREL1 PTK2 RAP1A RAP1B RARP1 RIAM SRC SRC1 TLN TLN1 VWF
VEGF binds to VEGFR leading to receptor dimerization	Placenta growth factor Vascular endothelial growth factor A, long form Vascular endothelial growth factor B Vascular endothelial growth factor C Vascular endothelial growth factor D Vascular endothelial growth factor receptor 1 Vascular endothelial growth factor receptor 2 Vascular endothelial growth factor receptor 3	O43915 P15692 P17948 P35916 P35968 P49763 P49765 P49767	FIGF FLK1 FLT FLT1 FLT4 FRT KDR PGF PGFL PLGF VEGF VEGFA VEGFB VEGFC VEGFD VEGFR1 VEGFR2 VEGFR3 VRF
activated TAK1 mediates p38 MAPK activation	Dual specificity mitogen-activated protein kinase kinase 3 Dual specificity mitogen-activated protein kinase kinase 6 Interleukin-1 receptor-associated kinase 1 Interleukin-1 receptor-associated kinase-like 2 MAP kinase-activated protein kinase 2 MAP kinase-activated protein kinase 3 Mitogen-activated protein kinase 11 Mitogen-activated protein kinase 14 Mitogen-activated protein kinase kinase kinase 7 NF-kappa-B essential modulator Nucleotide-binding oligomerization domain-containing protein 1 Nucleotide-binding oligomerization domain-containing protein 2 Receptor-interacting serine/threonine-protein kinase 2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 TNF receptor-associated factor 6 Ubiquitin-conjugating enzyme E2 N Ubiquitin-conjugating enzyme E2 variant 1	O43187 O43318 O43353 P46734 P49137 P51617 P52564 P61088 Q13404 Q15750 Q15759 Q16539 Q16644 Q8N5C8 Q9HC29 Q9NYJ8 Q9Y239 Q9Y4K3 Q9Y6K9	BLU CARD15 CARD4 CARDIAK CROC1 CSBP CSBP1 CSBP2 CSPB1 FIP3 IKBKG IRAK IRAK1 IRAK2 KIAA0733 MAP2K3 MAP2K6 MAP3K7 MAP3K7IP1 MAP3K7IP2 MAP3K7IP3 MAPK11 MAPK14 MAPKAPK2 MAPKAPK3 MEK3 MEK6 MKK3 MKK6 MXI2 NEMO NOD1 NOD2 PRKM11 PRKMK3 PRKMK6 RICK RIP2 RIPK2 RNF85 SAPK2 SAPK2A SAPK2B SKK2 SKK3 TAB1 TAB2 TAB3 TAK1 TRAF6 UBE2N UBE2V UBE2V1 UEV1
Intrinsic Pathway of Fibrin Clot Formation	Alpha-2-macroglobulin Antithrombin-III Coagulation factor IX Coagulation factor VIII Coagulation factor X Coagulation factor XI Coagulation factor XII Complement component 1 Q subcomponent-binding protein, mitochondrial Glia-derived nexin Heparin cofactor 2 Kininogen-1 Lysosomal Pro-X carboxypeptidase Plasma kallikrein Plasma protease C1 inhibitor Plasma serine protease inhibitor Platelet glycoprotein IX Platelet glycoprotein Ib alpha chain Platelet glycoprotein Ib beta chain Platelet glycoprotein V Prothrombin Vitamin K-dependent protein C Vitamin K-dependent protein S von Willebrand factor	P00451 P00734 P00740 P00742 P00748 P01008 P01023 P01042 P03951 P03952 P04070 P04275 P05154 P05155 P05546 P07093 P07225 P07359 P13224 P14770 P40197 P42785 Q07021	A2M AT3 BDK C1IN C1NH C1QBP CPAMD5 F10 F11 F12 F2 F8 F8C F8VWF F9 GC1QBP GP1BA GP1BB GP5 GP9 HABP1 HCF2 KLK3 KLKB1 KNG KNG1 PCI PCP PI7 PLANH3 PN1 PRCP PROC PROCI PROS PROS1 SERPINA5 SERPINC1 SERPIND1 SERPINE2 SERPING1 SF2P32 VWF
Degradation of GLI1 by the proteasome	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Cullin-1 E3 ubiquitin-protein ligase Itchy homolog E3 ubiquitin-protein ligase RBX1 F-box/WD repeat-containing protein 1A Polyubiquitin-B Polyubiquitin-C Proteasomal ubiquitin receptor ADRM1 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Protein numb homolog S-phase kinase-associated protein 1 Suppressor of fused homolog Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Zinc finger protein GLI1 cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit gamma	O00231 O00232 O00487 O14818 O43242 P08151 P0CG47 P0CG48 P17612 P17980 P20618 P22612 P22694 P25786 P25787 P25788 P25789 P28066 P28070 P28072 P28074 P35998 P43686 P48556 P49720 P49721 P49757 P51665 P60896 P60900 P62191 P62195 P62333 P62877 P62979 P62987 P63208 Q13200 Q13616 Q15008 Q16186 Q96J02 Q99436 Q99460 Q9UMX1 Q9UNM6 Q9Y297	ADRM1 BTRC BTRCP C14orf41 C7orf76 CUL1 DSS1 EMC19 FBW1A FBXW1A GLI GLI1 GP110 HC2 HC3 HC8 HC9 HSPC ITCH KIAA0107 LMPX LMPY MB1 MIP224 MOV34L MSS1 NU NUMB OCP2 PFAAP4 PKACA POH1 PRKACA PRKACB PRKACG PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PSMD8 RBX1 RNF75 ROC1 RPS27A SEM1 SHFDG1 SHFM1 SKP1 SKP1A SUFU SUG1 SUG2 TBP1 TBP7 TCEB1L TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 X Y Z
SHOC2 M1731 mutant abolishes MRAS complex function	14-3-3 protein beta/alpha Leucine-rich repeat protein SHOC-2 RAF proto-oncogene serine/threonine-protein kinase Ras-related protein M-Ras Serine/threonine-protein kinase A-Raf Serine/threonine-protein kinase B-raf Serine/threonine-protein phosphatase PP1-beta catalytic subunit Serine/threonine-protein phosphatase PP1-gamma catalytic subunit	O14807 P04049 P10398 P15056 P31946 P36873 P62140 Q9UQ13	ARAF ARAF1 BRAF BRAF1 KIAA0862 MRAS PKS PKS2 PPP1CB PPP1CC RAF RAF1 RAFB1 RRAS3 SHOC2 YWHAB
Signaling downstream of RAS mutants	14-3-3 protein beta/alpha Amyloid beta A4 precursor protein-binding family B member 1-interacting protein BRCA1-associated protein Beta-arrestin-1 Beta-arrestin-2 Calcium/calmodulin-dependent protein kinase type II subunit alpha Calcium/calmodulin-dependent protein kinase type II subunit beta Calcium/calmodulin-dependent protein kinase type II subunit delta Calcium/calmodulin-dependent protein kinase type II subunit gamma Calmodulin-1 Connector enhancer of kinase suppressor of ras 1 Connector enhancer of kinase suppressor of ras 2 Dual specificity mitogen-activated protein kinase kinase 1 Dual specificity mitogen-activated protein kinase kinase 2 Fibrinogen alpha chain Fibrinogen beta chain Fibrinogen gamma chain Fibronectin GTPase HRas GTPase KRas GTPase NRas Integrin alpha-IIb Integrin beta-3 Kinase suppressor of Ras 1 Kinase suppressor of Ras 2 MAP/microtubule affinity-regulating kinase 3 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Mitogen-activated protein kinase kinase kinase 11 Phosphatidylethanolamine-binding protein 1 Prohibitin 1 Proto-oncogene tyrosine-protein kinase Src RAF proto-oncogene serine/threonine-protein kinase Ras GTPase-activating-like protein IQGAP1 Ras-related protein Rap-1A Ras-related protein Rap-1b Serine/threonine-protein kinase A-Raf Serine/threonine-protein kinase B-raf Talin-1 Tyrosine-protein kinase CSK Tyrosine-protein kinase JAK2 Vinculin von Willebrand factor	O60674 P01111 P01112 P01116 P02671 P02675 P02679 P02751 P04049 P04275 P05106 P08514 P0DP23 P10398 P12931 P15056 P18206 P27361 P27448 P28482 P30086 P31946 P32121 P35232 P36507 P41240 P46940 P49407 P61224 P62834 Q02750 Q13554 Q13555 Q13557 Q16584 Q6VAB6 Q7Z569 Q7Z5R6 Q8IVT5 Q8WXI2 Q969H4 Q9UQM7 Q9Y490	APBB1IP ARAF ARAF1 ARB2 ARR1 ARR2 ARRB1 ARRB2 BRAF BRAF1 BRAP CALM CALM1 CAM CAM1 CAM2 CAMK CAMK-II CAMK2 CAMK2A CAMK2B CAMK2D CAMK2G CAMKA CAMKB CAMKD CAMKG CNK1 CNK2 CNKSR1 CNKSR2 CSK CTAK1 EMK2 ERK1 ERK2 F8VWF FGA FGB FGG FN FN1 GP2B GP3A HRAS HRAS1 IQGAP1 ITGA2B ITGAB ITGB3 JAK2 KIAA0051 KIAA0902 KIAA0968 KIAA1027 KRAS KRAS2 KREV1 KSR KSR1 KSR2 MAP2K1 MAP2K2 MAP3K11 MAPK1 MAPK3 MARK3 MEK1 MEK2 MKK2 MLK3 NRAS PBP PEBP PEBP1 PHB PHB1 PKS PKS2 PREL1 PRKM1 PRKM2 PRKM3 PRKMK1 PRKMK2 PTK1 RAF RAF1 RAFB1 RAP1A RAP1B RARP1 RASK2 RIAM RNF52 SPRK SRC SRC1 TLN TLN1 VCL VWF YWHAB
Phospholipase C-mediated cascade; FGFR3	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Fibroblast growth factor 16 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 4 Fibroblast growth factor 9	O43320 O76093 P05230 P08620 P09038 P19174 P31371 Q9GZV9 Q9NP95	FGF1 FGF16 FGF18 FGF2 FGF20 FGF23 FGF4 FGF9 FGFA FGFB HST HSTF1 HYPF KS3 PLC1 PLCG1
MyD88 cascade initiated on plasma membrane	Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial Flagellin Interleukin-1 receptor-associated kinase 1 Interleukin-1 receptor-associated kinase 4 Interleukin-1 receptor-associated kinase-like 2 Mitogen-activated protein kinase kinase kinase 1 Myeloid differentiation primary response protein MyD88 TNF receptor-associated factor 6 Toll-like receptor 10 Toll-like receptor 5	O43187 O60602 P04949 P51617 Q13233 Q99836 Q9BQ95 Q9BXR5 Q9NWZ3 Q9Y4K3	ECSIT IRAK IRAK1 IRAK2 IRAK4 MAP3K1 MAPKKK1 MEKK MEKK1 MYD88 RNF85 TIL3 TLR10 TLR5 TRAF6 flaF fliC hag
TBC/RABGAPs	ADP-ribosylation factor 6 ADP-ribosylation factor-binding protein GGA1 ADP-ribosylation factor-binding protein GGA2 ADP-ribosylation factor-binding protein GGA3 Carabin Gamma-aminobutyric acid receptor-associated protein-like 2 Gamma-aminobutyric acid receptor-associated protein Genome polyprotein Hamartin Microtubule-associated proteins 1A/1B light chain 3B Optineurin Rab GTPase-activating protein 1 Rab GTPase-binding effector protein 1 Rab5 GDP/GTP exchange factor Ras-related protein Rab-11A Ras-related protein Rab-11B Ras-related protein Rab-33A Ras-related protein Rab-33B Ras-related protein Rab-35 Ras-related protein Rab-4A Ras-related protein Rab-5A Ras-related protein Rab-5B Ras-related protein Rab-5C Ras-related protein Rab-6A Ras-related protein Rab-6B Ras-related protein Rab-7a Ras-related protein Rab-7b Ras-related protein Rab-8A Ras-related protein Rab-8B Serine/threonine-protein kinase ULK1 Synaptotagmin-like protein 1 TBC1 domain family member 10A TBC1 domain family member 10B TBC1 domain family member 13 TBC1 domain family member 14 TBC1 domain family member 15 TBC1 domain family member 16 TBC1 domain family member 17 TBC1 domain family member 20 TBC1 domain family member 24 TBC1 domain family member 25 TBC1 domain family member 2A TBC1 domain family member 3 TBC1 domain family member 7 Tuberin	O75385 O95166 P20338 P20339 P20340 P27958 P49815 P51148 P51149 P60520 P61006 P61020 P62330 P62491 Q14088 Q15276 Q15286 Q15907 Q3MII6 Q4KMP7 Q8IV04 Q8IYJ3 Q8IZP1 Q8TBP0 Q8TC07 Q92574 Q92930 Q96AH8 Q96BZ9 Q96CV9 Q9BXI6 Q9BYX2 Q9GZQ8 Q9H082 Q9HA65 Q9NRW1 Q9NVG8 Q9NZ52 Q9P0N9 Q9P2M4 Q9UJ41 Q9UJY4 Q9UJY5 Q9ULP9 Q9Y3P9	ARF6 C20orf140 EPI64 FIP2 FLC3A FLC3B GABARAP GABARAPL2 GEF2 GGA1 GGA2 GGA3 GLC1E HIP7 HYPL KIAA0154 KIAA0243 KIAA0722 KIAA1080 KIAA1171 KIAA1322 MAP1ALC3 MAP1LC3B MEL NRP OATL1 OPTN PARIS1 PP8997 PRC17 RAB11 RAB11A RAB11B RAB1C RAB33A RAB33B RAB35 RAB4 RAB4A RAB5 RAB5A RAB5B RAB5C RAB5EP RAB6 RAB6A RAB6B RAB7 RAB7A RAB7B RAB8 RAB8A RAB8B RABEP1 RABEX5 RABGAP1 RABGEF1 RABL RABPT5 RABPT5A RABS10 RAY SLP1 SYTL1 TBC1D10 TBC1D10A TBC1D10B TBC1D10C TBC1D13 TBC1D14 TBC1D15 TBC1D16 TBC1D17 TBC1D2 TBC1D20 TBC1D24 TBC1D25 TBC1D2A TBC1D3 TBC1D3A TBC1D7 TBC7 TSC TSC1 TSC2 TSC4 ULK1 YPT3
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB	Bridging integrator 2 Golgin subfamily A member 4 KN motif and ankyrin repeat domain-containing protein 1 Transcription factor ETV6 Vascular endothelial growth factor receptor 2	P35968 P41212 Q13439 Q14678 Q9UBW5	ANKRD15 BIN2 BRAP1 ETV6 FLK1 GOLGA4 KANK KANK1 KDR KIAA0172 TEL TEL1 VEGFR2
Activation of SMO	Beta-adrenergic receptor kinase 1 Beta-arrestin-1 Beta-arrestin-2 Brother of CDO Casein kinase I isoform alpha Cell adhesion molecule-related/down-regulated by oncogenes Desert hedgehog protein Dynein regulatory complex subunit 4 EF-hand calcium-binding domain-containing protein 7 EvC complex member EVC Growth arrest-specific protein 1 IQ domain-containing protein E Indian hedgehog protein Kinesin-like protein KIF3A Limbin Protein patched homolog 1 Protein smoothened Sonic hedgehog protein	A8K855 O43323 O95995 P25098 P32121 P48729 P49407 P54826 P57679 Q13635 Q14623 Q15465 Q4KMG0 Q6IPM2 Q86UK5 Q99835 Q9BWV1 Q9Y496	ADRBK1 ARB2 ARR1 ARR2 ARRB1 ARRB2 BARK BARK1 BOC CDO CDON CSNK1A1 DHH DRC4 EFCAB7 EVC EVC2 GAS1 GAS11 GAS8 GRK2 IHH IQCE KIAA1023 KIAA1799 KIF3 KIF3A LBN PTCH PTCH1 SHH SMO SMOH
G beta:gamma signalling through PI3Kgamma	3-phosphoinositide-dependent protein kinase 1 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform Phosphoinositide 3-kinase regulatory subunit 5 Phosphoinositide 3-kinase regulatory subunit 6 RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Transforming protein RhoA	O14610 O14775 O15530 O60262 P16520 P31749 P31751 P48736 P50150 P50151 P59768 P61586 P61952 P62873 P62879 P63211 P63215 P63218 Q5UE93 Q8WYR1 Q9HAV0 Q9P2W3 Q9UBI6 Q9UK08 Q9Y243	AKT1 AKT2 AKT3 ARH12 ARHA C17orf38 GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 PDK1 PDPK1 PIK3CG PIK3R5 PIK3R6 PKB PKBG RAC RHO12 RHOA
Acrosome Reaction and Sperm:Oocyte Membrane Binding	Acrosin CD9 antigen Izumo sperm-egg fusion protein 1 Izumo sperm-egg fusion protein 2 Izumo sperm-egg fusion protein 3 Izumo sperm-egg fusion protein 4	P10323 P21926 Q1ZYL8 Q5VZ72 Q6UXV1 Q8IYV9	ACR ACRS C19orf36 C19orf41 C9orf134 CD9 IZUMO1 IZUMO2 IZUMO3 IZUMO4 MIC3 SCRL TSPAN29
Mitochondrial Uncoupling	ADP/ATP translocase 1 Mitochondrial brown fat uncoupling protein 1	P12235 P25874	AAC1 ANT1 SLC25A4 SLC25A7 UCP UCP1
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation	ADP-ribosylation factor 1 AH receptor-interacting protein Annexin A2 BolA-like protein 2 Calponin-2 Carbonic anhydrase 1 Cell division control protein 42 homolog Cofilin-1 F-actin-capping protein subunit alpha-1 Glutathione S-transferase A2 Glutathione S-transferase omega-1 Heterogeneous nuclear ribonucleoprotein D-like Heterogeneous nuclear ribonucleoprotein F Heterogeneous nuclear ribonucleoproteins A2/B1 Interferon gamma Interleukin-10 Lamin-B1 Large ribosomal subunit protein uL10 Macrophage migration inhibitory factor Moesin Peptidyl-prolyl cis-trans isomerase A Phosphatidylinositol transfer protein alpha isoform Plasminogen activator inhibitor 2 Plastin-2 Programmed cell death protein 4 Proteasome activator complex subunit 2 Ras-related protein Ral-A Ras-related protein Rap-1b S-methyl-5'-thioadenosine phosphorylase Serine/threonine-protein kinase PAK 2 Signal transducer and activator of transcription 4 Stress-70 protein, mitochondrial Superoxide dismutase [Cu-Zn] Superoxide dismutase [Mn], mitochondrial T-complex protein 1 subunit alpha Transaldolase U2 small nuclear ribonucleoprotein A'	O00170 O14979 P00441 P00915 P01579 P04179 P05120 P05388 P07355 P09210 P09661 P11233 P13796 P14174 P17987 P20700 P22301 P22626 P23528 P26038 P37837 P38646 P52597 P52907 P60953 P61224 P62937 P78417 P84077 Q00169 Q13126 Q13177 Q14765 Q53EL6 Q99439 Q9H3K6 Q9UL46	AIP ANX2 ANX2L4 ANXA2 ARF1 BOLA2 BOLA2A BOLA2B CA1 CAL1H CAPZA1 CCT1 CCTA CDC42 CFL CFL1 CNN2 CYPA GLIF GRP75 GST2 GSTA2 GSTO1 GSTTLP28 H731 HNRNPA2B1 HNRNPDL HNRNPF HNRPA2B1 HNRPDL HNRPF HSPA9 HSPA9B IFNG IL10 JKTBP LCP1 LMN2 LMNB LMNB1 LPC2D MIF MMIF MSAP MSN MTAP PAI2 PAK2 PDCD4 PITPN PITPNA PLANH2 PLS2 PPIA PSME2 RAL RALA RAP1B RPLP0 SERPINB2 SNRPA1 SOD1 SOD2 STAT4 TAL TALDO TALDO1 TALDOR TCP1 XAP2 mt-HSP70
NADPH regeneration	Cytoplasmic aconitate hydratase Isocitrate dehydrogenase [NADP] cytoplasmic	O75874 P21399	ACO1 IDH1 IREB1 PICD
Defective visual phototransduction due to ABCA4 loss of function	Retinal-specific phospholipid-transporting ATPase ABCA4	P78363	ABCA4 ABCR
Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant	Delta-like protein 1 Delta-like protein 4 Disintegrin and metalloproteinase domain-containing protein 10 Disintegrin and metalloproteinase domain-containing protein 17 Neurogenic locus notch homolog protein 1 Protein jagged-1 Protein jagged-2	O00548 O14672 P46531 P78504 P78536 Q9NR61 Q9Y219	ADAM10 ADAM17 CSVP DLL1 DLL4 JAG1 JAG2 JAGL1 KUZ MADM NOTCH1 TACE TAN1
NOTCH3 Activation and Transmission of Signal to the Nucleus	Delta-like protein 1 Delta-like protein 4 Disintegrin and metalloproteinase domain-containing protein 10 E3 ubiquitin-protein ligase MIB1 E3 ubiquitin-protein ligase MIB2 E3 ubiquitin-protein ligase NEURL1 E3 ubiquitin-protein ligase NEURL1B Epidermal growth factor receptor Gamma-secretase subunit APH-1A Gamma-secretase subunit APH-1B Gamma-secretase subunit PEN-2 NEDD4-like E3 ubiquitin-protein ligase WWP2 Neurogenic locus notch homolog protein 3 Nicastrin Polyubiquitin-B Polyubiquitin-C Presenilin-1 Presenilin-2 Pro-epidermal growth factor Protein jagged-1 Protein jagged-2 Transforming acidic coiled-coil-containing protein 3 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A8MQ27 O00308 O00548 O14672 O76050 P00533 P01133 P0CG47 P0CG48 P49768 P49810 P62979 P62987 P78504 Q86YT6 Q8WW43 Q92542 Q96AX9 Q96BI3 Q9NR61 Q9NZ42 Q9UM47 Q9Y219 Q9Y6A5	AD3 AD4 ADAM10 APH1A APH1B DIP1 DLL1 DLL4 EGF EGFR ERBB ERBB1 ERIC1 HER1 JAG1 JAG2 JAGL1 KIAA0253 KIAA1323 KUZ MADM MIB1 MIB2 NCSTN NEURL NEURL1 NEURL1A NEURL1B NEURL3 NOTCH3 PEN2 PS1 PS2 PSEN1 PSEN2 PSENEN PSF PSFL PSNL1 PSNL2 RNF67 RPS27A SKD STM2 TACC3 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 WWP2 ZZANK1 ZZANK2

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