MAPK1 (ERK2) activation
|
|
|
- ERK2
- IFNB2
- IL6
- IL6R
- JAK1
- JAK1A
- JAK1B
- JAK2
- MAP2K2
- MAPK1
- MEK2
- MKK2
- PRKM1
- PRKM2
- PRKMK2
- PTP2C
- PTPN11
- SHPTP2
- TYK2
|
|
Recycling of bile acids and salts
|
|
|
- ABCB11
- ABCC3
- ACSB
- ACSVL6
- ALB
- ASBT
- BAAT
- BAR
- BHLHE74
- BHLHE75
- BSEP
- CMOAT2
- FABP6
- FACVL3
- FATP5
- FXR
- HRR1
- ILBP
- ILLBP
- ISBT
- LST1
- LST2
- MLP2
- MRP3
- NCOA1
- NCOA2
- NR1H4
- NR2B1
- NTCP
- NTCP2
- OATP
- OATP1
- OATP1A2
- OATP1B1
- OATP1B3
- OATP2
- OATP8
- OATPC
- OSTA
- OSTB
- RIP14
- RXRA
- SLC10A1
- SLC10A2
- SLC21A3
- SLC21A6
- SLC21A8
- SLC27A5
- SLC51A
- SLC51B
- SLCO1A2
- SLCO1B1
- SLCO1B3
- SRC1
- SRC2
- STARD5
- TIF2
|
|
RNA Polymerase II Transcription Termination
|
|
|
- ALY
- ALYREF
- ASF
- BAT1
- BEF
- C1orf77
- C22orf19
- CASC3
- CBP20
- CBP80
- CDC40
- CFIM25
- CHTOP
- CLP1
- COD
- CPSF1
- CPSF100
- CPSF160
- CPSF2
- CPSF25
- CPSF3
- CPSF30
- CPSF4
- CPSF5
- CPSF7
- CPSF73
- CSTF1
- CSTF2
- CSTF2T
- CSTF3
- CXorf3
- DDX38
- DDX39
- DDX39A
- DDX39B
- DDX48
- DHX38
- EHB3
- EIF4A3
- FIP1
- FIP1L1
- FOP
- FYTTD1
- HBP
- HCC1
- HEAB
- HPR1
- HRS
- KIAA0111
- KIAA0224
- KIAA0663
- KIAA0689
- KIAA0824
- KIAA0983
- KIAA1141
- KIAA1367
- KIAA1649
- LDC2
- LSM10
- LSM11
- LUZP4
- MAGOH
- MAGOH2
- MAGOHA
- MAGOHB
- MLN51
- NAR
- NCBP
- NCBP1
- NCBP2
- NEB1
- NIF3L1BP1
- NUDT21
- PAB2
- PABP2
- PABPN1
- PAP
- PAPOLA
- PBSCF
- PBSCG
- PCF11
- PDIP46
- POLDIP3
- PRP16
- PRP17
- PRPF17
- RBM8
- RBM8A
- RENT3B
- RHE
- RNPS1
- SARNP
- SF2
- SF2P33
- SFRS1
- SFRS11
- SFRS2
- SFRS3
- SFRS4
- SFRS5
- SFRS6
- SFRS7
- SFRS9
- SLBP
- SLU7
- SNRPB
- SNRPB1
- SNRPD3
- SNRPE
- SNRPF
- SNRPG
- SPK
- SRM160
- SRP20
- SRP30C
- SRP40
- SRP55
- SRP75
- SRRM1
- SRSF1
- SRSF11
- SRSF2
- SRSF3
- SRSF4
- SRSF5
- SRSF6
- SRSF7
- SRSF9
- SYMPK
- THOC1
- THOC2
- THOC3
- THOC4
- THOC5
- THOC6
- THOC7
- U2AF1
- U2AF1-RS3
- U2AF1L3
- U2AF1L4
- U2AF2
- U2AF35
- U2AF65
- U2AFBP
- UAP56
- UIF
- UPF3B
- UPF3X
- WDC146
- WDR33
- WDR58
- ZC3H11A
- ZC3HDC11A
- ZFP100
- ZNF473
|
|
Impaired BRCA2 binding to PALB2
|
|
|
- ATM
- BACH1
- BARD1
- BLM
- BRCA1
- BRCA2
- BRIP1
- C16orf75
- C9orf76
- CTIP
- DNA2
- DNA2L
- EXO1
- EXOI
- FACD
- FANCD1
- FANCJ
- FANCN
- HEX1
- HNGS1
- HTATIP
- KAT5
- KIAA0083
- MRE11
- MRE11A
- NBN
- NBS
- NBS1
- P95
- PALB2
- PIR51
- RAD50
- RAD51
- RAD51A
- RAD51AP1
- RAD51B
- RAD51C
- RAD51D
- RAD51L1
- RAD51L2
- RAD51L3
- RBBP8
- REC2
- RECA
- RECQ2
- RECQ3
- RECQL2
- RECQL3
- RMI1
- RMI2
- RNF53
- TIP60
- TOP3
- TOP3A
- WRN
- XRCC2
|
|
Signal regulatory protein family interactions
|
|
|
- BIT
- CD47
- DAP12
- FAK
- FAK1
- FAK2
- FYB
- FYB1
- HCP
- KARAP
- MER6
- MFR
- MYD1
- PRAP
- PTK2
- PTK2B
- PTP1C
- PTP2C
- PTPN11
- PTPN6
- PTPNS1
- PYK2
- RA70
- RAFTK
- SAPS
- SCAP2
- SHPS1
- SHPTP2
- SIRP
- SIRPA
- SIRPB1
- SIRPB2
- SIRPG
- SKAP2
- SKAP55R
- SLAP130
- TYROBP
|
|
Ephrin signaling
|
|
|
- ARHGEF7
- COOL1
- DRT
- EFL3
- EFNB1
- EFNB2
- EFNB3
- ELK
- EPHB1
- EPHB2
- EPHB3
- EPHB4
- EPHB6
- EPHT2
- EPHT3
- EPLG2
- EPLG5
- EPLG8
- EPTH3
- ERK
- ETK2
- FYN
- GIT1
- GRB4
- HEK2
- HEK5
- HEK6
- HTK
- HTKL
- KIAA0142
- LERK2
- LERK5
- LERK8
- MDA9
- MLCB
- MRLC3
- MYK1
- MYL12A
- NCK2
- NET
- OPHN3
- P85SPR
- PAK1
- PAK2
- PAK3
- PAK3BP
- PIXB
- RAC1
- RLC
- SDCBP
- SYCL
- TC25
- TYRO11
- TYRO5
- TYRO6
|
|
Defective SLC34A2 causes pulmonary alveolar microlithiasis (PALM)
|
|
|
|
|
RNA Polymerase II Transcription Initiation And Promoter Clearance
|
- CDK-activating kinase assembly factor MAT1
- Cyclin-H
- Cyclin-dependent kinase 7
- DNA-directed RNA polymerase II subunit RPB11-a
- DNA-directed RNA polymerase II subunit RPB1
- DNA-directed RNA polymerase II subunit RPB2
- DNA-directed RNA polymerase II subunit RPB3
- DNA-directed RNA polymerase II subunit RPB4
- DNA-directed RNA polymerase II subunit RPB7
- DNA-directed RNA polymerase II subunit RPB9
- DNA-directed RNA polymerases I, II, and III subunit RPABC1
- DNA-directed RNA polymerases I, II, and III subunit RPABC2
- DNA-directed RNA polymerases I, II, and III subunit RPABC3
- DNA-directed RNA polymerases I, II, and III subunit RPABC4
- DNA-directed RNA polymerases I, II, and III subunit RPABC5
- General transcription and DNA repair factor IIH helicase subunit XPD
- General transcription and DNA repair factor IIH helicase/translocase subunit XPB
- General transcription factor IIE subunit 1
- General transcription factor IIF subunit 1
- General transcription factor IIF subunit 2
- General transcription factor IIH subunit 1
- General transcription factor IIH subunit 2
- General transcription factor IIH subunit 3
- General transcription factor IIH subunit 4
- General transcription factor IIH subunit 5
- TATA-binding protein-associated factor 2N
- TATA-box-binding protein
- Transcription initiation factor IIA subunit 1
- Transcription initiation factor IIA subunit 2
- Transcription initiation factor IIB
- Transcription initiation factor IIE subunit beta
- Transcription initiation factor TFIID subunit 1-like
- Transcription initiation factor TFIID subunit 10
- Transcription initiation factor TFIID subunit 11
- Transcription initiation factor TFIID subunit 12
- Transcription initiation factor TFIID subunit 13
- Transcription initiation factor TFIID subunit 1
- Transcription initiation factor TFIID subunit 2
- Transcription initiation factor TFIID subunit 3
- Transcription initiation factor TFIID subunit 4
- Transcription initiation factor TFIID subunit 4B
- Transcription initiation factor TFIID subunit 5
- Transcription initiation factor TFIID subunit 6
- Transcription initiation factor TFIID subunit 7-like
- Transcription initiation factor TFIID subunit 7
- Transcription initiation factor TFIID subunit 9
- Transcription initiation factor TFIID subunit 9B
|
|
- BA2R
- BTF2
- BTF2P44
- C6orf175
- CAK
- CAK1
- CAP35
- CCG1
- CCGS
- CCNH
- CDK7
- CDKN7
- CIF150
- ERCC2
- ERCC3
- GTF2A1
- GTF2A2
- GTF2B
- GTF2D1
- GTF2E1
- GTF2E2
- GTF2F1
- GTF2F2
- GTF2H1
- GTF2H2
- GTF2H3
- GTF2H4
- GTF2H5
- MAT1
- MNAT1
- MO15
- POLR2
- POLR2A
- POLR2B
- POLR2C
- POLR2D
- POLR2E
- POLR2F
- POLR2G
- POLR2H
- POLR2I
- POLR2J
- POLR2J1
- POLR2K
- POLR2L
- POLRF
- RAP30
- RAP74
- RBP56
- RNF66
- RPB7
- STK1
- TAF1
- TAF10
- TAF11
- TAF12
- TAF13
- TAF15
- TAF1L
- TAF2
- TAF2A
- TAF2B
- TAF2C
- TAF2C1
- TAF2C2
- TAF2D
- TAF2E
- TAF2F
- TAF2G
- TAF2H
- TAF2I
- TAF2J
- TAF2K
- TAF2N
- TAF2Q
- TAF3
- TAF4
- TAF4A
- TAF4B
- TAF5
- TAF6
- TAF7
- TAF7L
- TAF9
- TAF9B
- TAF9L
- TAFII105
- TAFII130
- TAFII135
- TAFII18
- TAFII20
- TAFII30
- TAFII31
- TAFII55
- TAFII70
- TBP
- TF2A1
- TF2A2
- TF2B
- TF2D
- TF2E1
- TF2E2
- TFIIB
- TFIID
- TTDA
- XPB
- XPBC
- XPD
- XPDC
|
|
Autodegradation of the E3 ubiquitin ligase COP1
|
|
|
- ATM
- C7orf76
- COP1
- DSS1
- HC2
- HC3
- HC8
- HC9
- HSPC
- IFI5111
- KIAA0072
- KIAA0077
- KIAA0107
- LMP10
- LMP2
- LMP7
- LMPX
- LMPY
- MB1
- MCB1
- MECL1
- MIP224
- MOV34L
- MSS1
- NU
- P53
- PFAAP4
- POH1
- PROS26
- PROS27
- PROS30
- PSC2
- PSC3
- PSC5
- PSC8
- PSC9
- PSMA1
- PSMA2
- PSMA3
- PSMA4
- PSMA5
- PSMA6
- PSMA7
- PSMA7L
- PSMA8
- PSMB1
- PSMB10
- PSMB11
- PSMB2
- PSMB3
- PSMB4
- PSMB5
- PSMB5i
- PSMB6
- PSMB6i
- PSMB7
- PSMB8
- PSMB9
- PSMC1
- PSMC2
- PSMC3
- PSMC4
- PSMC5
- PSMC6
- PSMD1
- PSMD10
- PSMD11
- PSMD12
- PSMD13
- PSMD14
- PSMD2
- PSMD3
- PSMD4
- PSMD5
- PSMD6
- PSMD7
- PSMD8
- PSMD9
- PSME1
- PSME2
- PSME3
- PSME4
- PSMF1
- RFWD2
- RING10
- RING12
- RNF200
- RPS27A
- SEM1
- SHFDG1
- SHFM1
- SUG1
- SUG2
- TBP1
- TBP7
- TP53
- TRAP2
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
- X
- Y
- Y2
- Z
|
|
SIRT1 negatively regulates rRNA expression
|
|
|
- GTF2D1
- H2AB1
- H2AC14
- H2AC18
- H2AC19
- H2AC20
- H2AC4
- H2AC6
- H2AC7
- H2AC8
- H2AFA
- H2AFB1
- H2AFE
- H2AFG
- H2AFJ
- H2AFL
- H2AFM
- H2AFO
- H2AFQ
- H2AFV
- H2AFX
- H2AJ
- H2AV
- H2AX
- H2AZ2
- H2BC1
- H2BC10
- H2BC11
- H2BC12
- H2BC12L
- H2BC13
- H2BC14
- H2BC15
- H2BC17
- H2BC21
- H2BC26
- H2BC3
- H2BC4
- H2BC5
- H2BC6
- H2BC7
- H2BC8
- H2BC9
- H2BFA
- H2BFB
- H2BFC
- H2BFD
- H2BFE
- H2BFF
- H2BFG
- H2BFH
- H2BFJ
- H2BFK
- H2BFL
- H2BFN
- H2BFQ
- H2BFR
- H2BFS
- H2BFT
- H2BS1
- H2BU1
- H3-3A
- H3-3B
- H3.3A
- H3.3B
- H3C1
- H3C10
- H3C11
- H3C12
- H3C13
- H3C14
- H3C15
- H3C2
- H3C3
- H3C4
- H3C6
- H3C7
- H3C8
- H3F2
- H3F3
- H3F3A
- H3F3B
- H3FA
- H3FB
- H3FC HIST1H3C
- H3FD
- H3FF
- H3FH
- H3FI
- H3FJ
- H3FK
- H3FL
- H3FM
- H4-16
- H4/A
- H4/B
- H4/C
- H4/D
- H4/E
- H4/G
- H4/H
- H4/I
- H4/J
- H4/K
- H4/M
- H4/N
- H4/O
- H4C1
- H4C11
- H4C12
- H4C13
- H4C14
- H4C15
- H4C16
- H4C2
- H4C3
- H4C4
- H4C5
- H4C6
- H4C8
- H4C9
- H4F2
- H4FA
- H4FB
- H4FC
- H4FD
- H4FE
- H4FG
- H4FH
- H4FI
- H4FJ
- H4FK
- H4FM
- H4FN
- H4FO
- HIRIP1
- HIRIP2
- HIST1H2AB
- HIST1H2AC
- HIST1H2AD
- HIST1H2AE
- HIST1H2AJ
- HIST1H2BA
- HIST1H2BB
- HIST1H2BC
- HIST1H2BD
- HIST1H2BE
- HIST1H2BF
- HIST1H2BG
- HIST1H2BH
- HIST1H2BI
- HIST1H2BJ
- HIST1H2BK
- HIST1H2BL
- HIST1H2BM
- HIST1H2BN
- HIST1H2BO
- HIST1H3A
- HIST1H3B
- HIST1H3D
- HIST1H3E
- HIST1H3F
- HIST1H3G
- HIST1H3H
- HIST1H3I
- HIST1H3J
- HIST1H4A
- HIST1H4B
- HIST1H4C
- HIST1H4D
- HIST1H4E
- HIST1H4F
- HIST1H4H
- HIST1H4I
- HIST1H4J
- HIST1H4K
- HIST1H4L
- HIST2H2AA
- HIST2H2AA3
- HIST2H2AA4
- HIST2H2AC
- HIST2H2BE
- HIST2H3A
- HIST2H3C
- HIST2H3D
- HIST2H4
- HIST2H4A
- HIST2H4B
- HIST3H2BB
- HIST4H4
- JOSD3
- KIAA0409
- KMT1A
- NML
- RRP8
- SIR2L1
- SIRT1
- SUV39H
- SUV39H1
- TAF1A
- TAF1B
- TAF1C
- TAF1D
- TBP
- TF2D
- TFIID
- TSH2B
|
|
Synthesis of bile acids and bile salts
|
|
|
- BAR
- BHLHE74
- BHLHE75
- CH25H
- CYP7
- CYP7A1
- CYP7B1
- FXR
- HRR1
- KIAA0704
- KIAA0772
- NCOA1
- NCOA2
- NR1H4
- NR2B1
- ORP1
- ORP2
- ORP3
- ORP6
- ORP7
- ORP9
- OSBP
- OSBP1
- OSBP3
- OSBP4
- OSBP8
- OSBPL1
- OSBPL1A
- OSBPL1B
- OSBPL2
- OSBPL3
- OSBPL6
- OSBPL7
- OSBPL9
- RIP14
- RXRA
- SRC1
- SRC2
- TIF2
|
|
PTK6 Down-Regulation
|
|
|
- BRK
- C20orf148
- PTK6
- PTP1B
- PTPN1
- SRMS
|
|
Metabolism of ingested MeSeO2H into MeSeH
|
|
|
|
|
VEGF binds to VEGFR leading to receptor dimerization
|
|
|
- FIGF
- FLK1
- FLT
- FLT1
- FLT4
- FRT
- KDR
- PGF
- PGFL
- PLGF
- VEGF
- VEGFA
- VEGFB
- VEGFC
- VEGFD
- VEGFR1
- VEGFR2
- VEGFR3
- VRF
|
|
Termination of translesion DNA synthesis
|
|
|
- CHRAC17
- DINB1
- DPE2
- EFP
- G1P2
- ISG15
- KIAA0039
- KIAA0101
- KIAA0190
- NS5ATP9
- PAF
- PCLAF
- PCNA
- POLD
- POLD1
- POLD2
- POLD3
- POLD4
- POLDS
- POLE
- POLE1
- POLE2
- POLE3
- POLE4
- POLH
- POLI
- POLK
- RAD30
- RAD30A
- RAD30B
- REPA1
- REPA2
- REPA3
- REV1
- REV1L
- RFC1
- RFC140
- RFC2
- RFC3
- RFC4
- RFC5
- RNF147
- RPA1
- RPA14
- RPA2
- RPA3
- RPA32
- RPA34
- RPA70
- RPS27A
- TRIM25
- UBA52
- UBA7
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
- UBCH8
- UBE1L
- UBE2
- UBE2L6
- UCRP
- USP10
- USP43
- XPV
- ZNF147
|
|
InlA-mediated entry of Listeria monocytogenes into host cells
|
|
|
- CBLL1
- CDH1
- CDHE
- CTNNB
- CTNNB1
- CTNND1
- HAKAI
- KIAA0384
- RNF188
- RPS27A
- SRC
- SRC1
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
- UVO
- inlA
|
|
eNOS activation
|
|
|
- AKT1
- APT1
- CALM
- CALM1
- CAM
- CAM1
- CAV
- CAV1
- CYGB
- DDAH
- DDAH1
- HSP90A
- HSP90AA1
- HSPC1
- HSPCA
- LPL1
- LYPLA1
- NOS3
- PKB
- RAC
- SPR
- STAP
- ZDHHC21
|
|
Defective CSF2RB causes SMDP5
|
|
|
- COLEC4
- COLEC5
- COLEC7
- CSF2R
- CSF2RA
- CSF2RB
- CSF2RY
- IL3RB
- IL5RB
- PSAP
- PSPD
- SFTA3
- SFTP1
- SFTP2
- SFTP3
- SFTP4
- SFTPA
- SFTPA1
- SFTPA1B
- SFTPA2
- SFTPA2B
- SFTPB
- SFTPC
- SFTPD
- SFTPH
|
|
Defective ACY1 causes encephalopathy
|
|
|
|
|
Glycogen synthesis
|
|
|
- EPM2A
- EPM2B
- GBE1
- GYG
- GYG1
- GYG2
- GYS
- GYS1
- GYS2
- NHLRC1
- PGM1
- PPP1R3C
- PPP1R5
- RPS27A
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
- UGP1
- UGP2
|
|
EGR2 and SOX10-mediated initiation of Schwann cell myelination
|
|
|
- ACOD4
- ADGRG6
- ADGRV1
- BAF190A
- BHLHD2
- BRG1
- BRN2
- CYP51
- CYP51A1
- DAG1
- DMDL
- DREG
- DRP1
- DRP2
- EGR2
- GAS3
- GMA
- GPR126
- GPR98
- HDAC2
- HMGCR
- KIAA0686
- KIAA1620
- KIAA1943
- KROX20
- LAMA2
- LAMB1
- LAMB2
- LAMC1
- LAMM
- MADER
- MAG
- MASS1
- MBP
- MPZ
- NAB1
- NAB2
- OCT6
- OCT7
- OTF6
- OTF7
- PMP22
- POU3F1
- POU3F2
- PRX
- SCD2
- SCD4
- SCD5
- SMARCA4
- SNF2B
- SNF2L4
- SOX10
- SREBF2
- SREBP2
- TAZ
- TCF13
- TEAD1
- TEF1
- UTRN
- VIGR
- VLGR1
- WWTR1
- YAP1
- YAP65
|
|
Invadopodia formation
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- ADAM12
- ADAM15
- ADAM19
- FISH
- KIAA0418
- MDC15
- MLTN
- MLTNB
- SH3MD1
- SH3PXD2A
- TKS5
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Biotin transport and metabolism
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- ACAC
- ACACA
- ACACB
- ACC1
- ACC2
- ACCA
- ACCB
- AIPP1
- BTD
- HLCS
- MCCA
- MCCB
- MCCC1
- MCCC2
- PC
- PCCA
- PCCB
- PDZD11
- PDZK11
- PISP
- SLC5A6
- SMVT
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Antigen Presentation: Folding, assembly and peptide loading of class I MHC
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- 8
- ABCB2
- ABCB3
- APPILS
- ARTS1
- ATG14
- ATG14L
- B2M
- BECN1
- CALR
- CANX
- CRTC
- D3S1231E
- ERAP1
- ERAP2
- ERP57
- ERP60
- GRP58
- GRP78
- GT197
- HLA-5.4
- HLA-6.0
- HLA-6.2
- HLA-A
- HLA-B
- HLA-C
- HLA-E
- HLA-F
- HLA-G
- HLA-H
- HLAA
- HLAB
- HLAC
- HLAE
- HLAF
- HLAG
- HLAH
- HSPA5
- KIAA0079
- KIAA0525
- KIAA0755
- KIAA0831
- KIAA0905
- LRAP
- NGS17
- PDIA3
- PIK3C3
- PIK3R4
- PSF1
- PSF2
- RING11
- RING4
- SAR1B
- SARA2
- SARB
- SEC13
- SEC13A
- SEC13L1
- SEC13R
- SEC23A
- SEC24A
- SEC24B
- SEC24C
- SEC24D
- SEC31A
- SEC31L1
- TAP1
- TAP2
- TAPA
- TAPBP
- VPS15
- VPS34
- Y1
- Y3
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Transcriptional Regulation by MECP2
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- AGO1
- AGO2
- AGO3
- AGO4
- C22orf12
- CAGH26
- DGCR8
- DGCRK6
- EIF2C1
- EIF2C2
- EIF2C3
- EIF2C4
- GAMT
- IRAK
- IRAK1
- KIAA1093
- KIAA1460
- KIAA1567
- KIAA1582
- KIAA1631
- MMAC1
- MOBP
- MOV10
- PTEN
- PVALB
- SGK
- SGK1
- SOX2
- TEP1
- TNRC6
- TNRC6A
- TNRC6B
- TNRC6C
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