GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **251 - 275** of **2090** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism
Defective PMM2 causes CDG-1a	Phosphomannomutase 2	O15305	PMM2	Homo sapiens (human)
Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA	Insulin-like growth factor 2 mRNA-binding protein 1 Insulin-like growth factor 2 mRNA-binding protein 2 Insulin-like growth factor 2 mRNA-binding protein 3	O00425 Q9NZI8 Q9Y6M1	CRDBP IGF2BP1 IGF2BP2 IGF2BP3 IMP2 IMP3 KOC1 VICKZ1 VICKZ2 VICKZ3 ZBP1	Homo sapiens (human)
B-WICH complex positively regulates rRNA expression	Actin, cytoplasmic 1 DNA excision repair protein ERCC-6 DNA-directed RNA polymerase I subunit RPA12 DNA-directed RNA polymerase I subunit RPA1 DNA-directed RNA polymerase I subunit RPA2 DNA-directed RNA polymerase I subunit RPA34 DNA-directed RNA polymerase I subunit RPA43 DNA-directed RNA polymerase I subunit RPA49 DNA-directed RNA polymerases I and III subunit RPAC1 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 Glycogen synthase kinase-3 beta Histone H2A type 1-B/E Histone H2A type 1-C Histone H2A type 1-D Histone H2A type 1-J Histone H2A type 2-A Histone H2A type 2-C Histone H2A-Bbd type 1 Histone H2A.J Histone H2A.V Histone H2AX Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/F/G/I Histone H2B type 1-D Histone H2B type 1-H Histone H2B type 1-J Histone H2B type 1-K Histone H2B type 1-L Histone H2B type 1-M Histone H2B type 1-N Histone H2B type 1-O Histone H2B type 2-E Histone H2B type 3-B Histone H2B type F-S Histone H3.1 Histone H3.2 Histone H3.3 Histone H4 Histone acetyltransferase KAT2A Histone acetyltransferase KAT2B Histone acetyltransferase p300 Myb-binding protein 1A Nucleolar RNA helicase 2 Protein DEK Protein POLR1D, isoform 2 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 Splicing factor 3B subunit 1 TATA box-binding protein-associated factor RNA polymerase I subunit A TATA box-binding protein-associated factor RNA polymerase I subunit B TATA box-binding protein-associated factor RNA polymerase I subunit C TATA box-binding protein-associated factor RNA polymerase I subunit D TATA-box-binding protein Tyrosine-protein kinase BAZ1B	O15160 O15446 O60264 O60814 O75533 O95602 P04908 P06899 P0C5Y9 P0DPB5 P16104 P19388 P20226 P20671 P23527 P33778 P35659 P49841 P52434 P53803 P57053 P58876 P60709 P61218 P62805 P62807 P62875 P68431 P84243 Q03468 Q09472 Q15572 Q15573 Q16777 Q16778 Q3B726 Q53T94 Q6FI13 Q71DI3 Q71UI9 Q8N257 Q92830 Q92831 Q93077 Q93079 Q96A08 Q99877 Q99878 Q99879 Q99880 Q9BQG0 Q9BTM1 Q9GZS1 Q9H5J8 Q9H9Y6 Q9NR30 Q9P1U0 Q9UIG0	ACTB ASE1 BAZ1B CAST CD3EAP CSB DDX21 DEK EP300 ERCC6 GCN5 GCN5L2 GSK3B GTF2D1 H2AB1 H2AC14 H2AC18 H2AC19 H2AC20 H2AC4 H2AC6 H2AC7 H2AC8 H2AFA H2AFB1 H2AFE H2AFG H2AFJ H2AFL H2AFM H2AFO H2AFQ H2AFV H2AFX H2AJ H2AV H2AX H2AZ2 H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H2BFA H2BFB H2BFC H2BFD H2BFE H2BFF H2BFG H2BFH H2BFJ H2BFK H2BFL H2BFN H2BFQ H2BFR H2BFS H2BFT H2BS1 H2BU1 H3-3A H3-3B H3.3A H3.3B H3C1 H3C10 H3C11 H3C12 H3C13 H3C14 H3C15 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 H3F2 H3F3 H3F3A H3F3B H3FA H3FB H3FC HIST1H3C H3FD H3FF H3FH H3FI H3FJ H3FK H3FL H3FM H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HIRIP1 HIRIP2 HIST1H2AB HIST1H2AC HIST1H2AD HIST1H2AE HIST1H2AJ HIST1H2BA HIST1H2BB HIST1H2BC HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2BI HIST1H2BJ HIST1H2BK HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST1H3A HIST1H3B HIST1H3D HIST1H3E HIST1H3F HIST1H3G HIST1H3H HIST1H3I HIST1H3J HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H2AA HIST2H2AA3 HIST2H2AA4 HIST2H2AC HIST2H2BE HIST2H3A HIST2H3C HIST2H3D HIST2H4 HIST2H4A HIST2H4B HIST3H2BB HIST4H4 JOSD3 KAT2A KAT2B MYBBP1A P160 P300 PAF49 PAF53 PCAF POLR1A POLR1B POLR1C POLR1D POLR1E POLR1F POLR1G POLR1H POLR2E POLR2F POLR2H POLR2K POLR2L POLRF PRAF1 RPA12 SAP155 SF3B1 SMARCA5 SNF2H TAF1A TAF1B TAF1C TAF1D TBP TF2D TFIID TSH2B TWISTNB WBSC10 WBSCR10 WBSCR9 WCRF135 WSTF ZNRD1	Homo sapiens (human)
Signaling by RAF1 mutants	14-3-3 protein beta/alpha Amyloid beta A4 precursor protein-binding family B member 1-interacting protein Beta-arrestin-1 Beta-arrestin-2 Calcium/calmodulin-dependent protein kinase type II subunit alpha Calcium/calmodulin-dependent protein kinase type II subunit beta Calcium/calmodulin-dependent protein kinase type II subunit delta Calcium/calmodulin-dependent protein kinase type II subunit gamma Calmodulin-1 Connector enhancer of kinase suppressor of ras 1 Connector enhancer of kinase suppressor of ras 2 Dual specificity mitogen-activated protein kinase kinase 1 Dual specificity mitogen-activated protein kinase kinase 2 Fibrinogen alpha chain Fibrinogen beta chain Fibrinogen gamma chain Fibronectin GTPase HRas GTPase NRas Integrin alpha-IIb Integrin beta-3 Kinase suppressor of Ras 1 Kinase suppressor of Ras 2 MAP/microtubule affinity-regulating kinase 3 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Proto-oncogene tyrosine-protein kinase Src RAF proto-oncogene serine/threonine-protein kinase Ras GTPase-activating-like protein IQGAP1 Ras-related protein Rap-1A Ras-related protein Rap-1b Serine/threonine-protein kinase A-Raf Serine/threonine-protein kinase B-raf Talin-1 Tyrosine-protein kinase CSK Tyrosine-protein kinase JAK2 Vinculin von Willebrand factor	O60674 P01111 P01112 P02671 P02675 P02679 P02751 P04049 P04275 P05106 P08514 P0DP23 P10398 P12931 P15056 P18206 P27361 P27448 P28482 P31946 P32121 P36507 P41240 P46940 P49407 P61224 P62834 Q02750 Q13554 Q13555 Q13557 Q6VAB6 Q7Z5R6 Q8IVT5 Q8WXI2 Q969H4 Q9UQM7 Q9Y490	APBB1IP ARAF ARAF1 ARB2 ARR1 ARR2 ARRB1 ARRB2 BRAF BRAF1 CALM CALM1 CAM CAM1 CAM2 CAMK CAMK-II CAMK2 CAMK2A CAMK2B CAMK2D CAMK2G CAMKA CAMKB CAMKD CAMKG CNK1 CNK2 CNKSR1 CNKSR2 CSK CTAK1 EMK2 ERK1 ERK2 F8VWF FGA FGB FGG FN FN1 GP2B GP3A HRAS HRAS1 IQGAP1 ITGA2B ITGAB ITGB3 JAK2 KIAA0051 KIAA0902 KIAA0968 KIAA1027 KREV1 KSR KSR1 KSR2 MAP2K1 MAP2K2 MAPK1 MAPK3 MARK3 MEK1 MEK2 MKK2 NRAS PKS PKS2 PREL1 PRKM1 PRKM2 PRKM3 PRKMK1 PRKMK2 RAF RAF1 RAFB1 RAP1A RAP1B RARP1 RIAM SRC SRC1 TLN TLN1 VCL VWF YWHAB	Homo sapiens (human)
Regulation of gene expression in beta cells	DNA-binding protein RFX6 Forkhead box protein O1 Hepatocyte nuclear factor 1-alpha Hepatocyte nuclear factor 3-beta Hepatocyte nuclear factor 3-gamma Hepatocyte nuclear factor 4-gamma Hexokinase-4 Homeobox protein Nkx-2.2 Homeobox protein Nkx-6.1 Insulin Islet amyloid polypeptide Neurogenic differentiation factor 1 Paired box protein Pax-6 Pancreas/duodenum homeobox protein 1 Solute carrier family 2, facilitated glucose transporter member 2 Transcription factor MafA	O95096 P01308 P10997 P11168 P20823 P26367 P35557 P52945 P55318 P78426 Q12778 Q13562 Q14541 Q8HWS3 Q8NHW3 Q9Y261	AN2 BHLHA3 FKHR FOXA2 FOXA3 FOXO1 FOXO1A GCK GLUT2 HNF1A HNF3B HNF3G HNF4G IAPP INS IPF1 MAFA NEUROD NEUROD1 NKX2-2 NKX2.2 NKX2B NKX6-1 NKX6A NR2A2 PAX6 PDX1 RFX6 RFXDC1 SLC2A2 STF1 TCF1 TCF3B TCF3G	Homo sapiens (human)
Activated NTRK2 signals through CDK5	BDNF/NT-3 growth factors receptor Brain-derived neurotrophic factor Cyclin-dependent kinase 5 activator 1 Cyclin-dependent kinase 5 Ras-related C3 botulinum toxin substrate 1 Rho guanine nucleotide exchange factor TIAM1	P23560 P63000 Q00535 Q13009 Q15078 Q16620	BDNF CDK5 CDK5R CDK5R1 CDKN5 NCK5A NTRK2 PSSALRE RAC1 TC25 TIAM1 TRKB	Homo sapiens (human)
Enhanced binding of GP1BA variant to VWF multimer:collagen	Platelet glycoprotein IX Platelet glycoprotein Ib alpha chain Platelet glycoprotein Ib beta chain Platelet glycoprotein V von Willebrand factor	P04275 P07359 P13224 P14770 P40197	F8VWF GP1BA GP1BB GP5 GP9 VWF	Homo sapiens (human)
O-linked glycosylation of mucins	Acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase Alpha-1,4-N-acetylglucosaminyltransferase Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3 Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 4 Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 7 Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase Beta-1,4-galactosyltransferase 5 Beta-1,4-galactosyltransferase 6 C1GALT1-specific chaperone 1 Carbohydrate sulfotransferase 4 Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 Inactive polypeptide N-acetylgalactosaminyltransferase-like protein 5 Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase Mucin-12 Mucin-13 Mucin-15 Mucin-16 Mucin-17 Mucin-19 Mucin-1 Mucin-20 Mucin-21 Mucin-2 Mucin-3A Mucin-3B Mucin-4 Mucin-5AC Mucin-5B Mucin-6 Mucin-7 Mucin-like protein 1 N-acetylgalactosaminyltransferase 7 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 4 Polypeptide N-acetylgalactosaminyltransferase 10 Polypeptide N-acetylgalactosaminyltransferase 11 Polypeptide N-acetylgalactosaminyltransferase 12 Polypeptide N-acetylgalactosaminyltransferase 13 Polypeptide N-acetylgalactosaminyltransferase 14 Polypeptide N-acetylgalactosaminyltransferase 15 Polypeptide N-acetylgalactosaminyltransferase 16 Polypeptide N-acetylgalactosaminyltransferase 17 Polypeptide N-acetylgalactosaminyltransferase 18 Polypeptide N-acetylgalactosaminyltransferase 1 Polypeptide N-acetylgalactosaminyltransferase 2 Polypeptide N-acetylgalactosaminyltransferase 3 Polypeptide N-acetylgalactosaminyltransferase 4 Polypeptide N-acetylgalactosaminyltransferase 5 Polypeptide N-acetylgalactosaminyltransferase 6 Polypeptide N-acetylgalactosaminyltransferase 9 Polypeptide N-acetylgalactosaminyltransferase-like 6 Probable polypeptide N-acetylgalactosaminyltransferase 8 Queuosine-tRNA galactosyltransferase UDP-GlcNAc UDP-GlcNAc UDP-GlcNAc	O43286 O95395 P15941 P98088 Q02505 Q02742 Q02817 Q10471 Q10472 Q14435 Q49A17 Q5SSG8 Q67FW5 Q685J3 Q6IS24 Q6P9A2 Q6UX72 Q6W4X9 Q6ZMB0 Q6ZNI0 Q7Z4T8 Q7Z5P9 Q7Z7M8 Q7Z7M9 Q86SF2 Q86SR1 Q8IUC8 Q8IXK2 Q8N307 Q8N387 Q8N3T1 Q8N428 Q8N4A0 Q8NCG5 Q8NCL4 Q8NCW6 Q8NFL0 Q8TAX7 Q8WXI7 Q96DR8 Q96EU7 Q96FL9 Q99102 Q9BYG0 Q9C0J1 Q9H195 Q9H3R2 Q9HC84 Q9HCQ5 Q9NS00 Q9NY28 Q9NY97 Q9P109 Q9UBX8 Q9UKN1 Q9UNA3 Q9Y2A9	A4GNT B3GALT7 B3GALT8 B3GNT1 B3GNT2 B3GNT3 B3GNT4 B3GNT5 B3GNT6 B3GNT7 B3GNT8 B3GNT9 B3GNTL1 B4GALT5 B4GALT6 BGALT15 C1GALT1 C1GALT1C1 C20orf105 C6orf205 CA125 CHST4 COSMC DRCC1 GALNT1 GALNT10 GALNT11 GALNT12 GALNT13 GALNT14 GALNT15 GALNT16 GALNT17 GALNT18 GALNT2 GALNT3 GALNT4 GALNT5 GALNT6 GALNT7 GALNT8 GALNT9 GALNTL1 GALNTL2 GALNTL4 GALNTL5 GALNTL6 GCNT1 GCNT3 GCNT4 GCNT7 KIAA1130 KIAA1359 KIAA1918 MG2 MUC1 MUC11 MUC12 MUC13 MUC15 MUC16 MUC17 MUC19 MUC2 MUC20 MUC21 MUC3 MUC3A MUC3B MUC4 MUC5 MUC5AC MUC5B MUC6 MUC7 MUCL1 NACGT2 PUM QTGAL RECC SBEM SMUC TMEM3 WBSCR17	Homo sapiens (human)
Defective DHDDS causes RP59	Dehydrodolichyl diphosphate synthase complex subunit DHDDS Dehydrodolichyl diphosphate synthase complex subunit NUS1	Q86SQ9 Q96E22	C6orf68 DHDDS HDS NGBR NUS1	Homo sapiens (human)
Ligand-dependent caspase activation	Caspase-8 FAS-associated death domain protein FLICE inhibitory protein Lymphocyte antigen 96 Monocyte differentiation antigen CD14 Receptor-interacting serine/threonine-protein kinase 1 TIR domain-containing adapter molecule 1 TIR domain-containing adapter molecule 2 TNF receptor-associated factor 2 Toll-like receptor 4 Tumor necrosis factor ligand superfamily member 10 Tumor necrosis factor ligand superfamily member 6 Tumor necrosis factor receptor superfamily member 10A Tumor necrosis factor receptor superfamily member 10B Tumor necrosis factor receptor superfamily member 6 Tumor necrosis factor receptor type 1-associated DEATH domain protein Viral CASP8 and FADD-like apoptosis regulator	O00206 O00220 O14763 P08571 P25445 P48023 P50591 Q12933 Q13158 Q13546 Q14790 Q15628 Q76RF1 Q86XR7 Q8IUC6 Q98325 Q9Y6Y9	APO2 APO2L APT1 APT1LG1 CASP8 CD14 CD95L DR4 DR5 ESOP1 FADD FAS FAS1 FASL FASLG KILLER LY96 MC159L MCH5 MD2 MORT1 ORF71 PRVTIRB RIP RIP1 RIPK1 TICAM1 TICAM2 TIRAP3 TIRP TLR4 TNFRSF10A TNFRSF10B TNFRSF6 TNFSF10 TNFSF6 TRADD TRAF2 TRAIL TRAILR1 TRAILR2 TRAM TRAP3 TRICK2 TRIF ZTNFR9	Homo sapiens (human)
Localization of the PINCH-ILK-PARVIN complex to focal adhesions	Alpha-parvin Integrin beta-1 Integrin-linked protein kinase Paxillin	P05556 P49023 Q13418 Q9NVD7	FNRB ILK ILK1 ILK2 ITGB1 MDF2 MSK12 MXRA2 PARVA PXN	Homo sapiens (human)
Defective PGM1 causes CDG1t	Phosphoglucomutase-1	P36871	PGM1	Homo sapiens (human)
Methylation	Adenosylhomocysteinase Arsenite methyltransferase Catechol O-methyltransferase Cytochrome P450 1A2 Glutathione S-transferase omega-1 Methionine adenosyltransferase 2 subunit beta Methionine synthase reductase Methionine synthase Methyltransferase N6AMT1 Multifunctional methyltransferase subunit TRM112-like protein Nicotinamide N-methyltransferase S-adenosylmethionine synthase isoform type-1 S-adenosylmethionine synthase isoform type-2 Thiopurine S-methyltransferase	P05177 P21964 P23526 P31153 P40261 P51580 P78417 Q00266 Q99707 Q9HBK9 Q9NZL9 Q9UBK8 Q9UI30 Q9Y5N5	AHCY AMS1 AMS2 AS3MT C21orf127 COMT CYP1A2 CYT19 GSTO1 GSTTLP28 HEMK2 KMT9 MAT1A MAT2A MAT2B MATA1 MATA2 MTR MTRR N6AMT1 NNMT PRED28 SAHH TGR TPMT TRMT112	Homo sapiens (human)
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes	ATP-binding cassette sub-family A member 6 Agouti-related protein Ataxin-3 Catalase E3 ubiquitin-protein ligase TRIM63 F-box only protein 32 Forkhead box protein O1 Forkhead box protein O3 Forkhead box protein O4 Forkhead box protein O6 Glucocorticoid receptor Glucose-6-phosphatase catalytic subunit 1 Hexokinase-4 Histone deacetylase 1 Histone deacetylase 2 Insulin-like growth factor-binding protein 1 Insulin Mothers against decapentaplegic homolog 2 Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 4 NAD-dependent protein deacetylase sirtuin-3, mitochondrial Paired amphipathic helix protein Sin3a Peroxisome proliferator-activated receptor gamma coactivator 1-alpha Phosphoenolpyruvate carboxykinase, cytosolic [GTP] Plexin-A4 Pro-neuropeptide Y Pro-opiomelanocortin Resistin Sterol regulatory element-binding protein 1 Superoxide dismutase [Mn], mitochondrial	A8MYZ6 O00253 O43524 P01189 P01303 P01308 P04040 P04150 P04179 P08833 P35557 P35558 P35575 P36956 P54252 P84022 P98177 Q12778 Q13485 Q13547 Q15796 Q8N139 Q92769 Q969P5 Q969Q1 Q96ST3 Q9HCM2 Q9HD89 Q9NTG7 Q9UBK2	ABCA6 AFX AFX1 AGRP AGRT ART ATX3 ATXN3 BHLHD1 CAT DPC4 FBXO32 FIZZ3 FKHR FKHRL1 FOXO1 FOXO1A FOXO3 FOXO3A FOXO4 FOXO6 G6PC G6PC1 G6PT GCK GRL HDAC1 HDAC2 HXCP1 IBP1 IGFBP1 INS IRF KIAA1550 LEM6 MADH2 MADH3 MADH4 MADR2 MJD MJD1 MLLT7 MURF1 NPY NR3C1 PCK1 PEPCK1 PGC1 PGC1A PLXNA4 PLXNA4A PLXNA4B POMC PPARGC1 PPARGC1A RETN RNF28 RPD3L1 RSTN SCA3 SIN3A SIR2L3 SIRT3 SMAD2 SMAD3 SMAD4 SMRZ SOD2 SREBF1 SREBP1 TRIM63	Homo sapiens (human)
Abasic sugar-phosphate removal via the single-nucleotide replacement pathway	DNA polymerase beta DNA repair nuclease/redox regulator APEX1	P06746 P27695	APE APE1 APEX APEX1 APX HAP1 POLB REF1	Homo sapiens (human)
Sensing of DNA Double Strand Breaks	DNA repair protein RAD50 Double-strand break repair protein MRE11 Histone acetyltransferase KAT5 Importin subunit alpha-1 Nibrin Serine-protein kinase ATM	O60934 P49959 P52292 Q13315 Q92878 Q92993	ATM HNGS1 HTATIP KAT5 KPNA2 MRE11 MRE11A NBN NBS NBS1 P95 RAD50 RCH1 SRP1 TIP60	Homo sapiens (human)
Neurophilin interactions with VEGF and VEGFR	Neuropilin-1 Neuropilin-2 Vascular endothelial growth factor receptor 1 Vascular endothelial growth factor receptor 2	O14786 O60462 P17948 P35968	FLK1 FLT FLT1 FRT KDR NRP NRP1 NRP2 VEGF165R VEGF165R2 VEGFR1 VEGFR2	Homo sapiens (human)
Asparagine N-linked glycosylation	Asialoglycoprotein receptor 1 Asialoglycoprotein receptor 2 Beta-1,4 N-acetylgalactosaminyltransferase 2 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A Magnesium transporter protein 1 Tumor suppressor candidate 3 Uromodulin	P04843 P04844 P07306 P07307 P07911 P39656 P46977 P61803 Q13454 Q8NHY0 Q9H0U3	ASGR1 ASGR2 B4GALNT2 CLEC4H1 CLEC4H2 DAD1 DDOST GALGT2 IAG2 ITM1 KIAA0115 MAGT1 N33 OST48 RPN1 RPN2 STT3A TMC TUSC3 UMOD	Homo sapiens (human)
UNC93B1 deficiency - HSE	Protein unc-93 homolog B1 Toll-like receptor 3	O15455 Q9H1C4	TLR3 UNC93 UNC93B UNC93B1	Homo sapiens (human)
FGFRL1 modulation of FGFR1 signaling	Fibroblast growth factor 10 Fibroblast growth factor 18 Fibroblast growth factor 22 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor 4 Fibroblast growth factor receptor-like 1 Sprouty-related, EVH1 domain-containing protein 1 Sprouty-related, EVH1 domain-containing protein 2	O15520 O76093 P08620 P09038 P11487 Q7Z698 Q7Z699 Q8N441 Q9GZV9 Q9HCT0	FGF10 FGF18 FGF2 FGF22 FGF23 FGF3 FGF4 FGFB FGFR5 FGFRL1 FHFR HST HSTF1 HYPF INT2 KS3 SPRED1 SPRED2	Homo sapiens (human)
G beta:gamma signalling through PI3Kgamma	3-phosphoinositide-dependent protein kinase 1 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform Phosphoinositide 3-kinase regulatory subunit 5 Phosphoinositide 3-kinase regulatory subunit 6 RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Transforming protein RhoA	O14610 O14775 O15530 O60262 P16520 P31749 P31751 P48736 P50150 P50151 P59768 P61586 P61952 P62873 P62879 P63211 P63215 P63218 Q5UE93 Q8WYR1 Q9HAV0 Q9P2W3 Q9UBI6 Q9UK08 Q9Y243	AKT1 AKT2 AKT3 ARH12 ARHA C17orf38 GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 PDK1 PDPK1 PIK3CG PIK3R5 PIK3R6 PKB PKBG RAC RHO12 RHOA	Homo sapiens (human)
G0 and Early G1	Cyclin-A1 Cyclin-A2 Cyclin-dependent kinase 2 Dual specificity tyrosine-phosphorylation-regulated kinase 1A G1/S-specific cyclin-E1 G1/S-specific cyclin-E2 Histone deacetylase 1 Histone-binding protein RBBP4 Protein lin-37 homolog Protein lin-52 homolog Protein lin-54 homolog Protein lin-9 homolog Retinoblastoma-like protein 1 Retinoblastoma-like protein 2 Transcription factor Dp-1 Transcription factor Dp-2 Transcription factor E2F4 Transcription factor E2F5	O96020 P20248 P24864 P24941 P28749 P78396 Q08999 Q09028 Q13547 Q13627 Q14186 Q14188 Q15329 Q16254 Q52LA3 Q5TKA1 Q6MZP7 Q96GY3	BARA C14orf46 CCN1 CCNA CCNA1 CCNA2 CCNE CCNE1 CCNE2 CDK2 CDKN2 CXCDC1 DP1 DP2 DYRK DYRK1A E2F4 E2F5 HDAC1 KIAA2037 LIN37 LIN52 LIN54 LIN9 MNB MNBH RB2 RBAP48 RBBP4 RBL1 RBL2 RPD3L1 TFDP1 TFDP2 TGS	Homo sapiens (human)
Downstream signal transduction	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Adapter molecule crk Breast cancer anti-estrogen resistance protein 1 Crk-like protein Cytoplasmic protein NCK2 GTPase HRas GTPase NRas Growth factor receptor-bound protein 7 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Platelet-derived growth factor receptor alpha Platelet-derived growth factor receptor beta Platelet-derived growth factor subunit B Proto-oncogene tyrosine-protein kinase Src Rap guanine nucleotide exchange factor 1 Ras GTPase-activating protein 1 SH2/SH3 adapter protein NCK1 Signal transducer and activator of transcription 1-alpha/beta Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Signal transducer and activator of transcription 6 Son of sevenless homolog 1 Tyrosine-protein phosphatase non-receptor type 11	O00459 O43639 P01111 P01112 P01127 P09619 P12931 P16234 P16333 P19174 P20936 P27986 P40763 P42224 P42226 P42229 P42336 P42338 P46108 P46109 P51692 P56945 Q06124 Q07889 Q13905 Q14451	APRF BCAR1 CAS CASS1 CRK CRKAS CRKL GAP GRB1 GRB4 GRB7 GRF2 HRAS HRAS1 NCK NCK1 NCK2 NRAS PDGF2 PDGFB PDGFR PDGFR1 PDGFR2 PDGFRA PDGFRB PIK3C1 PIK3CA PIK3CB PIK3R1 PIK3R2 PLC1 PLCG1 PTP2C PTPN11 RAPGEF1 RASA RASA1 RHEPDGFRA SHPTP2 SIS SOS1 SRC SRC1 STAT1 STAT3 STAT5 STAT5A STAT5B STAT6	Homo sapiens (human)
HDR through Single Strand Annealing (SSA)	ATR-interacting protein BRCA1-associated RING domain protein 1 Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN Breast cancer type 1 susceptibility protein Cell cycle checkpoint control protein RAD9A Cell cycle checkpoint control protein RAD9B Cell cycle checkpoint protein RAD17 Cell cycle checkpoint protein RAD1 Checkpoint protein HUS1 DNA endonuclease RBBP8 DNA excision repair protein ERCC-1 DNA repair endonuclease XPF DNA repair protein RAD50 DNA repair protein RAD51 homolog 1 DNA repair protein RAD52 homolog DNA replication ATP-dependent helicase/nuclease DNA2 DNA topoisomerase 2-binding protein 1 DNA topoisomerase 3-alpha Double-strand break repair protein MRE11 Exonuclease 1 Fanconi anemia group J protein Histone acetyltransferase KAT5 Nibrin RAD9, HUS1, RAD1-interacting nuclear orphan protein 1 RecQ-like DNA helicase BLM RecQ-mediated genome instability protein 1 RecQ-mediated genome instability protein 2 Replication factor C subunit 2 Replication factor C subunit 3 Replication factor C subunit 4 Replication factor C subunit 5 Replication protein A 14 kDa subunit Replication protein A 32 kDa subunit Replication protein A 70 kDa DNA-binding subunit Serine-protein kinase ATM Serine/threonine-protein kinase ATR Tyrosine-protein kinase ABL1	O60671 O60921 O60934 O75943 P00519 P07992 P15927 P27694 P35244 P35249 P35250 P38398 P40937 P40938 P43351 P49959 P51530 P54132 Q06609 Q13315 Q13472 Q13535 Q14191 Q6WBX8 Q8WXE1 Q92547 Q92878 Q92889 Q92993 Q96E14 Q99638 Q99708 Q99728 Q9BSD3 Q9BX63 Q9H9A7 Q9UQ84	ABL ABL1 AGS1 ATM ATR ATRIP BACH1 BARD1 BLM BRCA1 BRIP1 C12orf32 C16orf75 C9orf76 CTIP DNA2 DNA2L ERCC1 ERCC11 ERCC4 EXO1 EXOI FANCJ FRP1 HEX1 HNGS1 HTATIP HUS1 JTK7 KAT5 KIAA0083 KIAA0259 MRE11 MRE11A NBN NBS NBS1 P95 R24L RAD1 RAD17 RAD50 RAD51 RAD51A RAD52 RAD9A RAD9B RBBP8 REC1 RECA RECQ2 RECQ3 RECQL2 RECQL3 REPA1 REPA2 REPA3 RFC2 RFC3 RFC4 RFC5 RHINO RHNO1 RMI1 RMI2 RNF53 RPA1 RPA14 RPA2 RPA3 RPA32 RPA34 RPA70 TIP60 TOP3 TOP3A TOPBP1 WRN XPF	Homo sapiens (human)
Toxicity of botulinum toxin type E (botE)	Botulinum neurotoxin type E NTNHA Synaptic vesicle glycoprotein 2A Synaptic vesicle glycoprotein 2B Synaptosomal-associated protein 25	P60880 Q00496 Q7L0J3 Q7L1I2 Q9LBS8	KIAA0735 KIAA0736 SNAP SNAP25 SV2A SV2B botE ntnha	Homo sapiens (human)

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