GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **451 - 475** of **2090** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▲	Organism	GlyTouCan ID
Glycolysis	ADP-dependent glucokinase ATP-dependent 6-phosphofructokinase, liver type ATP-dependent 6-phosphofructokinase, muscle type ATP-dependent 6-phosphofructokinase, platelet type Alpha-enolase Beta-enolase Bisphosphoglycerate mutase Enolase 4 Fructose-bisphosphate aldolase A Fructose-bisphosphate aldolase B Fructose-bisphosphate aldolase C Gamma-enolase Glucosamine-6-phosphate isomerase 1 Glucosamine-6-phosphate isomerase 2 Glucose 1,6-bisphosphate synthase Glucose-6-phosphate isomerase Glyceraldehyde-3-phosphate dehydrogenase, testis-specific Glyceraldehyde-3-phosphate dehydrogenase Glycerol-3-phosphate phosphatase Hexokinase HKDC1 Hexokinase-1 Hexokinase-2 Hexokinase-3 Hexokinase-4 Phosphoglycerate kinase 1 Phosphoglycerate kinase 2 Phosphoglycerate mutase 1 Phosphoglycerate mutase 2 Triosephosphate isomerase	A6NDG6 A6NNW6 O14556 P00558 P04075 P04406 P05062 P06733 P06744 P07205 P07738 P08237 P09104 P09972 P13929 P15259 P17858 P18669 P19367 P35557 P46926 P52789 P52790 P60174 Q01813 Q2TB90 Q6PCE3 Q8TDQ7 Q9BRR6	ADPGK ALDA ALDB ALDC ALDOA ALDOB ALDOC BM32A BPGM C10orf134 ENO1 ENO1L1 ENO2 ENO3 ENO4 GAPD GAPD2 GAPDH GAPDH2 GAPDHS GAPDS GCK GNP2 GNPDA1 GNPDA2 GNPI GPI HK1 HK2 HK3 HKDC1 HLN KIAA0060 MBPB1 MPB1 PFKF PFKL PFKM PFKP PFKX PGAM1 PGAM2 PGAMA PGAMM PGK1 PGK2 PGKA PGKB PGM2L1 PGP TPI TPI1	Homo sapiens (human)	G58161NS
Acyl chain remodeling of DAG and TAG	1-acylglycerol-3-phosphate O-acyltransferase PNPLA3 Acyl-CoA wax alcohol acyltransferase 2 Diacylglycerol O-acyltransferase 1 Diacylglycerol O-acyltransferase 2-like protein 6 Diacylglycerol O-acyltransferase 2 Monoglyceride lipase Patatin-like phospholipase domain-containing protein 2	O75907 Q6E213 Q6ZPD8 Q96AD5 Q96PD7 Q99685 Q9NST1	ADPN AGRP1 ATGL AWAT2 C22orf20 DC3 DC4 DGAT DGAT1 DGAT2 DGAT2L4 DGAT2L6 MFAT MGLL PNPLA2 PNPLA3 WS	Homo sapiens (human)
POLB-Dependent Long Patch Base Excision Repair	ADP-ribosylhydrolase ARH3 DNA ligase 1 DNA polymerase beta DNA repair nuclease/redox regulator APEX1 Flap endonuclease 1 Poly [ADP-ribose] polymerase 1 Poly [ADP-ribose] polymerase 2 Poly(ADP-ribose) glycohydrolase	P06746 P09874 P18858 P27695 P39748 Q86W56 Q9NX46 Q9UGN5	ADPRHL2 ADPRS ADPRT ADPRT2 ADPRTL2 APE APE1 APEX APEX1 APX ARH3 FEN1 HAP1 LIG1 PARG PARP1 PARP2 POLB PPOL RAD2 REF1	Homo sapiens (human)
Phosphate bond hydrolysis by NUDT proteins	ADP-sugar pyrophosphatase Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase Nucleotide triphosphate diphosphatase NUDT15 U8 snoRNA-decapping enzyme	Q3LIE5 Q96DE0 Q9NV35 Q9UKK9	ADPRM C17orf48 MTH2 NUDIX5 NUDT15 NUDT16 NUDT5	Homo sapiens (human)
Formation of Incision Complex in GG-NER	CDK-activating kinase assembly factor MAT1 Centrin-2 Chromodomain-helicase-DNA-binding protein 1-like Cullin-4A Cullin-4B Cyclin-H Cyclin-dependent kinase 7 DNA damage-binding protein 1 DNA damage-binding protein 2 DNA excision repair protein ERCC-1 DNA excision repair protein ERCC-5 DNA repair endonuclease XPF DNA repair protein complementing XP-A cells DNA repair protein complementing XP-C cells E3 SUMO-protein ligase PIAS1 E3 SUMO-protein ligase PIAS3 E3 ubiquitin-protein ligase Arkadia E3 ubiquitin-protein ligase RBX1 General transcription and DNA repair factor IIH helicase subunit XPD General transcription and DNA repair factor IIH helicase/translocase subunit XPB General transcription factor IIH subunit 1 General transcription factor IIH subunit 2 General transcription factor IIH subunit 3 General transcription factor IIH subunit 4 General transcription factor IIH subunit 5 Poly [ADP-ribose] polymerase 1 Poly [ADP-ribose] polymerase 2 Polyubiquitin-B Polyubiquitin-C Replication protein A 14 kDa subunit Replication protein A 32 kDa subunit Replication protein A 70 kDa DNA-binding subunit SUMO-conjugating enzyme UBC9 Small ubiquitin-related modifier 1 Small ubiquitin-related modifier 2 Small ubiquitin-related modifier 3 UV excision repair protein RAD23 homolog A UV excision repair protein RAD23 homolog B Ubiquitin carboxyl-terminal hydrolase 45 Ubiquitin-conjugating enzyme E2 N Ubiquitin-conjugating enzyme E2 variant 2 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O75925 P07992 P09874 P0CG47 P0CG48 P15927 P18074 P19447 P23025 P27694 P28715 P32780 P35244 P41208 P50613 P51946 P51948 P54725 P54727 P55854 P61088 P61956 P62877 P62979 P62987 P63165 P63279 Q01831 Q13619 Q13620 Q13888 Q13889 Q15819 Q16531 Q6ZNA4 Q6ZYL4 Q70EL2 Q86WJ1 Q92466 Q92759 Q92889 Q9UGN5 Q9Y6X2	ADPRT ADPRT2 ADPRTL2 ALC1 BLU BTF2 BTF2P44 C6orf175 CAK CAK1 CALT CAP35 CCNH CDK7 CDKN7 CEN2 CETN2 CHD1L CUL4A CUL4B DDB1 DDB2 DDXBP1 ERCC1 ERCC11 ERCC2 ERCC3 ERCC4 ERCC5 ERCM2 GTF2H1 GTF2H2 GTF2H3 GTF2H4 GTF2H5 KIAA0695 MAT1 MMS2 MNAT1 MO15 PARP1 PARP2 PIAS1 PIAS3 PPOL RAD23A RAD23B RBX1 REPA1 REPA2 REPA3 RNF111 RNF66 RNF75 ROC1 RPA1 RPA14 RPA2 RPA3 RPA32 RPA34 RPA70 RPS27A SMT3A SMT3B SMT3C SMT3H1 SMT3H2 SMT3H3 STK1 SUMO1 SUMO2 SUMO3 TTDA UBA52 UBA80 UBB UBC UBC9 UBCE9 UBCEP1 UBCEP2 UBE2I UBE2N UBE2V2 UBL1 UEV2 USP45 XAP1 XPA XPAC XPB XPBC XPC XPCC XPD XPDC XPF XPG XPGC	Homo sapiens (human)
Dual Incision in GG-NER	Chromodomain-helicase-DNA-binding protein 1-like Cullin-4A Cullin-4B DNA damage-binding protein 1 DNA damage-binding protein 2 DNA excision repair protein ERCC-1 DNA excision repair protein ERCC-5 DNA polymerase delta catalytic subunit DNA polymerase delta subunit 2 DNA polymerase delta subunit 3 DNA polymerase delta subunit 4 DNA polymerase epsilon catalytic subunit A DNA polymerase epsilon subunit 2 DNA polymerase epsilon subunit 3 DNA polymerase epsilon subunit 4 DNA polymerase kappa DNA repair endonuclease XPF DNA repair protein complementing XP-A cells E3 ubiquitin-protein ligase RBX1 General transcription and DNA repair factor IIH helicase subunit XPD General transcription and DNA repair factor IIH helicase/translocase subunit XPB General transcription factor IIH subunit 1 General transcription factor IIH subunit 2 General transcription factor IIH subunit 3 General transcription factor IIH subunit 4 General transcription factor IIH subunit 5 Poly [ADP-ribose] polymerase 1 Poly [ADP-ribose] polymerase 2 Polyubiquitin-B Polyubiquitin-C Proliferating cell nuclear antigen Replication factor C subunit 1 Replication factor C subunit 2 Replication factor C subunit 3 Replication factor C subunit 4 Replication factor C subunit 5 Replication protein A 14 kDa subunit Replication protein A 32 kDa subunit Replication protein A 70 kDa DNA-binding subunit Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	P07992 P09874 P0CG47 P0CG48 P12004 P15927 P18074 P19447 P23025 P27694 P28340 P28715 P32780 P35244 P35249 P35250 P35251 P40937 P40938 P49005 P56282 P62877 P62979 P62987 Q07864 Q13619 Q13620 Q13888 Q13889 Q15054 Q16531 Q6ZYL4 Q86WJ1 Q92466 Q92759 Q92889 Q9HCU8 Q9NR33 Q9NRF9 Q9UBT6 Q9UGN5	ADPRT ADPRT2 ADPRTL2 ALC1 BTF2 BTF2P44 C6orf175 CHD1L CHRAC17 CUL4A CUL4B DDB1 DDB2 DINB1 DPE2 ERCC1 ERCC11 ERCC2 ERCC3 ERCC4 ERCC5 ERCM2 GTF2H1 GTF2H2 GTF2H3 GTF2H4 GTF2H5 KIAA0039 KIAA0695 PARP1 PARP2 PCNA POLD POLD1 POLD2 POLD3 POLD4 POLDS POLE POLE1 POLE2 POLE3 POLE4 POLK PPOL RBX1 REPA1 REPA2 REPA3 RFC1 RFC140 RFC2 RFC3 RFC4 RFC5 RNF75 ROC1 RPA1 RPA14 RPA2 RPA3 RPA32 RPA34 RPA70 RPS27A TTDA UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 XAP1 XPA XPAC XPB XPBC XPD XPDC XPF XPG XPGC	Homo sapiens (human)
HDR through MMEJ (alt-NHEJ)	Breast cancer type 2 susceptibility protein DNA endonuclease RBBP8 DNA ligase 3 DNA polymerase theta DNA repair protein RAD50 DNA repair protein RAD52 homolog DNA repair protein XRCC1 Double-strand break repair protein MRE11 Flap endonuclease 1 Nibrin Poly [ADP-ribose] polymerase 1 Poly [ADP-ribose] polymerase 2	O60934 O75417 P09874 P18887 P39748 P43351 P49916 P49959 P51587 Q92878 Q99708 Q9UGN5	ADPRT ADPRT2 ADPRTL2 BRCA2 CTIP FACD FANCD1 FEN1 HNGS1 LIG3 MRE11 MRE11A NBN NBS NBS1 P95 PARP1 PARP2 POLH POLQ PPOL RAD2 RAD50 RAD52 RBBP8 XRCC1	Homo sapiens (human)
Downregulation of SMAD2/3:SMAD4 transcriptional activity	E3 ubiquitin-protein ligase Arkadia E3 ubiquitin-protein ligase NEDD4-like E3 ubiquitin-protein ligase SMURF2 E3 ubiquitin-protein ligase TRIM33 Histone deacetylase 1 Homeobox protein TGIF1 Homeobox protein TGIF2 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Mothers against decapentaplegic homolog 2 Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 4 Mothers against decapentaplegic homolog 7 Nuclear receptor corepressor 1 Nuclear receptor corepressor 2 Poly [ADP-ribose] polymerase 1 Polyubiquitin-B Polyubiquitin-C Protein ATP1B4 Protein phosphatase 1A SNW domain-containing protein 1 Ski oncogene Ski-like protein Ubiquitin carboxyl-terminal hydrolase 9X Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 D3 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein WW domain-containing transcription regulator protein 1	O15105 O75376 P09874 P0CG47 P0CG48 P12755 P12757 P27361 P28482 P35813 P51668 P61077 P62979 P62987 P84022 Q13485 Q13547 Q13573 Q15583 Q15796 Q6ZNA4 Q93008 Q96PU5 Q9GZN2 Q9GZV5 Q9HAU4 Q9UN42 Q9UPN9 Q9Y618	ADPRT ATP1B4 CTG26 DFFRX DPC4 ERK1 ERK2 FAM HDAC1 KIAA0439 KIAA1047 KIAA1113 MADH2 MADH3 MADH4 MADH7 MADH8 MADR2 MAPK1 MAPK3 NCOR1 NCOR2 NEDD4L NEDL3 PARP1 PPM1A PPOL PPPM1A PRKM1 PRKM2 PRKM3 RFG7 RNF111 RPD3L1 RPS27A SFT SKI SKIIP SKIL SKIP SMAD2 SMAD3 SMAD4 SMAD7 SMURF2 SNO SNW1 TAZ TGIF TGIF1 TGIF2 TIF1G TRIM33 UBA52 UBA80 UBB UBC UBC5A UBC5C UBCEP1 UBCEP2 UBCH5 UBCH5A UBCH5C UBE2D1 UBE2D3 USP9 USP9X WWTR1	Homo sapiens (human)
vRNA Synthesis	Nucleoprotein Poly [ADP-ribose] polymerase 1 Polymerase acidic protein Polymerase basic protein 2 RNA-directed RNA polymerase catalytic subunit	P03428 P03431 P03433 P03466 P09874	ADPRT NP PA PARP1 PB1 PB2 PPOL	Homo sapiens (human)
Nicotinamide salvaging	7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase ATP-dependent (S)-NAD(P)H-hydrate dehydratase NAD(P)H-hydrate epimerase NAD-capped RNA hydrolase NUDT12 Nicotinamide N-methyltransferase Nicotinamide phosphoribosyltransferase Nicotinate phosphoribosyltransferase Prostacyclin synthase Prostaglandin G/H synthase 2 Protein mono-ADP-ribosyltransferase PARP10 Protein mono-ADP-ribosyltransferase PARP14 Protein mono-ADP-ribosyltransferase PARP16 Protein mono-ADP-ribosyltransferase PARP4 Protein mono-ADP-ribosyltransferase PARP6 Protein mono-ADP-ribosyltransferase PARP8 Protein mono-ADP-ribosyltransferase PARP9 Renalase Sodium-coupled monocarboxylate transporter 1 Solute carrier family 22 member 13	P35354 P40261 P43490 Q16647 Q2NL67 Q460N5 Q53GL7 Q5VYX0 Q6XQN6 Q8IW45 Q8IXQ6 Q8N3A8 Q8N5Y8 Q8N695 Q8NCW5 Q9BQG2 Q9UKK3 Q9UNU6 Q9Y226	ADPRTL1 AIBP AIT APOA1BP ARTD15 BAL BAL1 BAL2 C10orf59 C15orf30 CARKD COX2 CYP12 CYP8 CYP8A1 CYP8B1 FHIP KIAA0177 KIAA1268 NAMPT NAPRT NAPRT1 NAXD NAXE NNMT NUDT12 OCTL1 ORCTL3 PARP10 PARP14 PARP16 PARP4 PARP6 PARP8 PARP9 PARPL PBEF PBEF1 PTGIS PTGS2 RNLS SLC22A13 SLC5A8 SMCT SMCT1 YJEFN1	Homo sapiens (human)
Maturation of nucleoprotein	Casein kinase I isoform alpha Glycogen synthase kinase-3 alpha Glycogen synthase kinase-3 beta Nucleoprotein Protein arginine N-methyltransferase 1 Protein mono-ADP-ribosyltransferase PARP10 Protein mono-ADP-ribosyltransferase PARP14 Protein mono-ADP-ribosyltransferase PARP16 Protein mono-ADP-ribosyltransferase PARP4 Protein mono-ADP-ribosyltransferase PARP6 Protein mono-ADP-ribosyltransferase PARP8 Protein mono-ADP-ribosyltransferase PARP9 SRSF protein kinase 1 SRSF protein kinase 2 SUMO-conjugating enzyme UBC9 Small ubiquitin-related modifier 1	P0DTC9 P48729 P49840 P49841 P63165 P63279 P78362 Q2NL67 Q460N5 Q53GL7 Q8IXQ6 Q8N3A8 Q8N5Y8 Q96SB4 Q99873 Q9UKK3	ADPRTL1 ARTD15 BAL BAL1 BAL2 C15orf30 CSNK1A1 GSK3A GSK3B HMT2 HRMT1L2 IR1B4 KIAA0177 KIAA1268 N PARP10 PARP14 PARP16 PARP4 PARP6 PARP8 PARP9 PARPL PRMT1 SMT3C SMT3H3 SRPK1 SRPK2 SUMO1 UBC9 UBCE9 UBE2I UBL1	Homo sapiens (human)
Maturation of nucleoprotein	Glycogen synthase kinase-3 alpha Glycogen synthase kinase-3 beta Nucleoprotein Protein mono-ADP-ribosyltransferase PARP10 Protein mono-ADP-ribosyltransferase PARP14 Protein mono-ADP-ribosyltransferase PARP16 Protein mono-ADP-ribosyltransferase PARP4 Protein mono-ADP-ribosyltransferase PARP6 Protein mono-ADP-ribosyltransferase PARP8 Protein mono-ADP-ribosyltransferase PARP9 SUMO-conjugating enzyme UBC9 Small ubiquitin-related modifier 1	P49840 P49841 P59595 P63165 P63279 Q2NL67 Q460N5 Q53GL7 Q8IXQ6 Q8N3A8 Q8N5Y8 Q9UKK3	ADPRTL1 ARTD15 BAL BAL1 BAL2 C15orf30 GSK3A GSK3B KIAA0177 KIAA1268 N PARP10 PARP14 PARP16 PARP4 PARP6 PARP8 PARP9 PARPL SMT3C SMT3H3 SUMO1 UBC9 UBCE9 UBE2I UBL1	Homo sapiens (human)
Sealing of the nuclear envelope (NE) by ESCRT-III	Charged multivesicular body protein 2a Charged multivesicular body protein 2b Charged multivesicular body protein 3 Charged multivesicular body protein 4a Charged multivesicular body protein 4b Charged multivesicular body protein 4c Charged multivesicular body protein 6 Charged multivesicular body protein 7 Coiled-coil and C2 domain-containing protein 1B IST1 homolog LEM domain-containing protein 2 Putative tubulin-like protein alpha-4B Spastin Tubulin alpha chain-like 3 Tubulin alpha-1A chain Tubulin alpha-1B chain Tubulin alpha-1C chain Tubulin alpha-3C chain Tubulin alpha-3D chain Tubulin alpha-3E chain Tubulin alpha-4A chain Tubulin alpha-8 chain Tubulin beta 8B Tubulin beta-1 chain Tubulin beta-2A chain Tubulin beta-2B chain Tubulin beta-3 chain Tubulin beta-4A chain Tubulin beta-4B chain Tubulin beta-6 chain Tubulin beta-8 chain Vacuolar protein sorting-associated protein 4A	A6NHL2 A6NNZ2 O43633 P04350 P0DPH7 P0DPH8 P53990 P68363 P68366 P68371 Q13509 Q13885 Q3ZCM7 Q5T0F9 Q6PEY2 Q71U36 Q8NC56 Q8WUX9 Q96CF2 Q96FZ7 Q9BQE3 Q9BUF5 Q9BVA1 Q9BY43 Q9H444 Q9H4B7 Q9H853 Q9NY65 Q9UBP0 Q9UN37 Q9UQN3 Q9Y3E7	ADPSP BC2 C14orf123 C20orf178 CC2D1B CGI149 CHMP2 CHMP2A CHMP2B CHMP3 CHMP4A CHMP4B CHMP4C CHMP6 CHMP7 FSP2 IST1 KIAA0174 KIAA1083 KIAA1836 LEMD2 LGD1 NEDF SHAX1 SHAX2 SHAX3 SPAST SPG4 TUBA1 TUBA1A TUBA1B TUBA1C TUBA2 TUBA3 TUBA3C TUBA3D TUBA3E TUBA4 TUBA4A TUBA4B TUBA6 TUBA8 TUBAL2 TUBAL3 TUBB1 TUBB2 TUBB2A TUBB2B TUBB2C TUBB3 TUBB4 TUBB4A TUBB4B TUBB5 TUBB6 TUBB8 TUBB8B VPS20 VPS24 VPS4 VPS4A	Homo sapiens (human)
Adrenoceptors	Alpha-1A adrenergic receptor Alpha-1B adrenergic receptor Alpha-1D adrenergic receptor Alpha-2A adrenergic receptor Alpha-2B adrenergic receptor Alpha-2C adrenergic receptor Beta-1 adrenergic receptor Beta-2 adrenergic receptor Beta-3 adrenergic receptor	P07550 P08588 P08913 P13945 P18089 P18825 P25100 P35348 P35368	ADRA1A ADRA1B ADRA1C ADRA1D ADRA2A ADRA2B ADRA2C ADRA2L1 ADRA2L2 ADRA2R ADRA2RL1 ADRA2RL2 ADRAR ADRB1 ADRB1R ADRB2 ADRB2R ADRB3 ADRB3R B1AR B2AR B3AR	Homo sapiens (human)
Adrenaline signalling through Alpha-2 adrenergic receptor	Alpha-2A adrenergic receptor Alpha-2B adrenergic receptor Alpha-2C adrenergic receptor	P08913 P18089 P18825	ADRA2A ADRA2B ADRA2C ADRA2L1 ADRA2L2 ADRA2R ADRA2RL1 ADRA2RL2 ADRAR	Homo sapiens (human)
Serotonin receptors	5-hydroxytryptamine receptor 1A 5-hydroxytryptamine receptor 1B 5-hydroxytryptamine receptor 1D 5-hydroxytryptamine receptor 1E 5-hydroxytryptamine receptor 1F 5-hydroxytryptamine receptor 2A 5-hydroxytryptamine receptor 2B 5-hydroxytryptamine receptor 2C 5-hydroxytryptamine receptor 4 5-hydroxytryptamine receptor 5A 5-hydroxytryptamine receptor 6 5-hydroxytryptamine receptor 7	P08908 P28221 P28222 P28223 P28335 P28566 P30939 P34969 P41595 P47898 P50406 Q13639	ADRB2RL1 ADRBRL1 HTR1A HTR1B HTR1C HTR1D HTR1DA HTR1DB HTR1E HTR1EL HTR1F HTR2 HTR2A HTR2B HTR2C HTR4 HTR5A HTR6 HTR7 HTRL	Homo sapiens (human)
Activation of SMO	Beta-adrenergic receptor kinase 1 Beta-arrestin-1 Beta-arrestin-2 Brother of CDO Casein kinase I isoform alpha Cell adhesion molecule-related/down-regulated by oncogenes Desert hedgehog protein Dynein regulatory complex subunit 4 EF-hand calcium-binding domain-containing protein 7 EvC complex member EVC Growth arrest-specific protein 1 IQ domain-containing protein E Indian hedgehog protein Kinesin-like protein KIF3A Limbin Protein patched homolog 1 Protein smoothened Sonic hedgehog protein	A8K855 O43323 O95995 P25098 P32121 P48729 P49407 P54826 P57679 Q13635 Q14623 Q15465 Q4KMG0 Q6IPM2 Q86UK5 Q99835 Q9BWV1 Q9Y496	ADRBK1 ARB2 ARR1 ARR2 ARRB1 ARRB2 BARK BARK1 BOC CDO CDON CSNK1A1 DHH DRC4 EFCAB7 EVC EVC2 GAS1 GAS11 GAS8 GRK2 IHH IQCE KIAA1023 KIAA1799 KIF3 KIF3A LBN PTCH PTCH1 SHH SMO SMOH	Homo sapiens (human)
Calmodulin induced events	Beta-adrenergic receptor kinase 1 Calmodulin-1 Protein kinase C alpha type Protein kinase C delta type Protein kinase C gamma type	P05129 P0DP23 P17252 P25098 Q05655	ADRBK1 BARK BARK1 CALM CALM1 CAM CAM1 GRK2 PKCA PKCD PKCG PRKACA PRKCA PRKCD PRKCG	Homo sapiens (human)
WNT5A-dependent internalization of FZD4	AP-2 complex subunit alpha-1 AP-2 complex subunit alpha-2 AP-2 complex subunit beta AP-2 complex subunit mu AP-2 complex subunit sigma Beta-arrestin-2 Clathrin heavy chain 1 Clathrin light chain A Clathrin light chain B Frizzled-4 Protein Wnt-5a Protein kinase C alpha type Protein kinase C beta type Protein kinase C gamma type Segment polarity protein dishevelled homolog DVL-2	O14641 O94973 O95782 P05129 P05771 P09496 P09497 P17252 P32121 P41221 P53680 P63010 Q00610 Q96CW1 Q9ULV1	ADTAA ADTAB ADTB2 AP17 AP2A1 AP2A2 AP2B1 AP2M1 AP2S1 ARB2 ARR2 ARRB2 CLAPA1 CLAPA2 CLAPB1 CLAPM1 CLAPS2 CLH17 CLTA CLTB CLTC CLTCL2 DVL2 FZD4 HIP9 HYPJ KIAA0034 KIAA0109 KIAA0899 PKCA PKCB PKCG PRKACA PRKCA PRKCB PRKCB1 PRKCG WNT5A	Homo sapiens (human)
Nef Mediated CD4 Down-regulation	ADP-ribosylation factor 1 AP-2 complex subunit alpha-1 AP-2 complex subunit alpha-2 AP-2 complex subunit beta AP-2 complex subunit mu AP-2 complex subunit sigma Protein Nef T-cell surface glycoprotein CD4 Tyrosine-protein kinase Lck V-type proton ATPase subunit H	O94973 O95782 P01730 P04601 P06239 P53680 P63010 P84077 Q96CW1 Q9UI12	ADTAA ADTAB ADTB2 AP17 AP2A1 AP2A2 AP2B1 AP2M1 AP2S1 ARF1 ATP6V1H CD4 CLAPA1 CLAPA2 CLAPB1 CLAPM1 CLAPS2 HIP9 HYPJ KIAA0109 KIAA0899 LCK nef	Homo sapiens (human)
Nef Mediated CD8 Down-regulation	AP-2 complex subunit alpha-1 AP-2 complex subunit alpha-2 AP-2 complex subunit beta AP-2 complex subunit mu AP-2 complex subunit sigma Protein Nef T-cell surface glycoprotein CD8 beta chain V-type proton ATPase subunit H	O94973 O95782 P04601 P10966 P53680 P63010 Q96CW1 Q9UI12	ADTAA ADTAB ADTB2 AP17 AP2A1 AP2A2 AP2B1 AP2M1 AP2S1 ATP6V1H CD8B CD8B1 CLAPA1 CLAPA2 CLAPB1 CLAPM1 CLAPS2 HIP9 HYPJ KIAA0109 KIAA0899 nef	Homo sapiens (human)
VLDLR internalisation and degradation	AP-2 complex subunit alpha-1 AP-2 complex subunit alpha-2 AP-2 complex subunit beta AP-2 complex subunit mu AP-2 complex subunit sigma Clathrin heavy chain 1 Clathrin light chain A E3 ubiquitin-protein ligase MYLIP Oxysterols receptor LXR-alpha Oxysterols receptor LXR-beta Polyubiquitin-B Polyubiquitin-C Proprotein convertase subtilisin/kexin type 9 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Very low-density lipoprotein receptor	O94973 O95782 P09496 P0CG47 P0CG48 P53680 P55055 P62979 P62987 P63010 P98155 Q00610 Q13133 Q8NBP7 Q8WY64 Q96CW1	ADTAA ADTAB ADTB2 AP17 AP2A1 AP2A2 AP2B1 AP2M1 AP2S1 BZF1 CLAPA1 CLAPA2 CLAPB1 CLAPM1 CLAPS2 CLH17 CLTA CLTC CLTCL2 HIP9 HYPJ IDOL KIAA0034 KIAA0109 KIAA0899 LXRA LXRB MYLIP NARC1 NER NR1H2 NR1H3 PCSK9 RPS27A UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 UNR VLDLR	Homo sapiens (human)
Recycling pathway of L1	AP-2 complex subunit alpha-1 AP-2 complex subunit alpha-2 AP-2 complex subunit beta AP-2 complex subunit mu AP-2 complex subunit sigma Chromosome-associated kinesin KIF4A Chromosome-associated kinesin KIF4B Clathrin heavy chain 1 Clathrin light chain A Dihydropyrimidinase-related protein 2 Dynamin-1 Dynamin-2 Dynamin-3 Endophilin-A1 Ezrin Mitogen-activated protein kinase 1 Moesin Neural cell adhesion molecule L1 Protein numb homolog Radixin Ribosomal protein S6 kinase alpha-1 Ribosomal protein S6 kinase alpha-2 Ribosomal protein S6 kinase alpha-3 Ribosomal protein S6 kinase alpha-4 Ribosomal protein S6 kinase alpha-5 Ribosomal protein S6 kinase alpha-6 Shootin-1	A0MZ66 O75582 O75676 O94973 O95239 O95782 P09496 P15311 P26038 P28482 P32004 P35241 P49757 P50570 P51812 P53680 P63010 Q00610 Q05193 Q15349 Q15418 Q16555 Q2VIQ3 Q96CW1 Q99962 Q9UK32 Q9UQ16	ADTAA ADTAB ADTB2 AP17 AP2A1 AP2A2 AP2B1 AP2M1 AP2S1 C14orf41 CAML1 CLAPA1 CLAPA2 CLAPB1 CLAPM1 CLAPS2 CLH17 CLTA CLTC CLTCL2 CNSA2 CRMP2 DNM DNM1 DNM2 DNM3 DPYSL2 DYN2 ERK2 EZR HIP9 HYPJ ISPK1 KIAA0034 KIAA0109 KIAA0820 KIAA0899 KIAA1598 KIF4 KIF4A KIF4B L1CAM MAPK1 MAPKAPK1A MAPKAPK1B MAPKAPK1C MIC5 MSK1 MSK2 MSN NUMB PRKM1 PRKM2 RDX RPS6KA1 RPS6KA2 RPS6KA3 RPS6KA4 RPS6KA5 RPS6KA6 RSK1 RSK2 RSK3 RSK4 SH3D2A SH3GL2 SHTN1 ULIP2 VIL2	Homo sapiens (human)
WNT5A-dependent internalization of FZD2, FZD5 and ROR2	AP-2 complex subunit alpha-1 AP-2 complex subunit alpha-2 AP-2 complex subunit beta AP-2 complex subunit mu AP-2 complex subunit sigma Clathrin heavy chain 1 Clathrin light chain A Clathrin light chain B Frizzled-2 Frizzled-5 Inactive tyrosine-protein kinase transmembrane receptor ROR1 Protein Wnt-5a Tyrosine-protein kinase transmembrane receptor ROR2	O94973 O95782 P09496 P09497 P41221 P53680 P63010 Q00610 Q01973 Q01974 Q13467 Q14332 Q96CW1	ADTAA ADTAB ADTB2 AP17 AP2A1 AP2A2 AP2B1 AP2M1 AP2S1 C2orf31 CLAPA1 CLAPA2 CLAPB1 CLAPM1 CLAPS2 CLH17 CLTA CLTB CLTC CLTCL2 FZD2 FZD5 HIP9 HYPJ KIAA0034 KIAA0109 KIAA0899 NTRKR1 NTRKR2 ROR1 ROR2 WNT5A	Homo sapiens (human)
Retrograde neurotrophin signalling	AP-2 complex subunit alpha-1 AP-2 complex subunit alpha-2 AP-2 complex subunit beta AP-2 complex subunit mu AP-2 complex subunit sigma Beta-nerve growth factor Clathrin heavy chain 1 Clathrin light chain A Dynamin-1 Dynamin-2 Dynamin-3 Dynein axonemal light chain 4 Endophilin-A1 High affinity nerve growth factor receptor	O94973 O95782 O96015 P01138 P04629 P09496 P50570 P53680 P63010 Q00610 Q05193 Q96CW1 Q99962 Q9UQ16	ADTAA ADTAB ADTB2 AP17 AP2A1 AP2A2 AP2B1 AP2M1 AP2S1 CLAPA1 CLAPA2 CLAPB1 CLAPM1 CLAPS2 CLH17 CLTA CLTC CLTCL2 CNSA2 DNAL4 DNM DNM1 DNM2 DNM3 DYN2 HIP9 HYPJ KIAA0034 KIAA0109 KIAA0820 KIAA0899 MTC NGF NGFB NTRK1 SH3D2A SH3GL2 TRK TRKA	Homo sapiens (human)

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