GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **951 - 975** of **2090** in total

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Pathway Name	Protein Name	UniProt ID ▼	Gene Symbol	Organism
APOBEC3G mediated resistance to HIV-1 infection	Barrier-to-autointegration factor Gag polyprotein Gag-Pol polyprotein High mobility group protein HMG-I/HMG-Y PC4 and SFRS1-interacting protein Peptidyl-prolyl cis-trans isomerase A Protein Rev Protein Vpr Protein Vpu Virion infectivity factor	O75475 O75531 P04585 P04591 P04618 P05919 P17096 P62937 P69723 P69726	BAF BANF1 BCRG1 CYPA DFS70 HMGA1 HMGIY LEDGF PPIA PSIP1 PSIP2 gag gag-pol rev vif vpr vpu	Homo sapiens (human)
Integration of provirus	Barrier-to-autointegration factor Gag polyprotein Gag-Pol polyprotein High mobility group protein HMG-I/HMG-Y Importin subunit alpha-5 PC4 and SFRS1-interacting protein Peptidyl-prolyl cis-trans isomerase A Protein Rev Protein Vpr Protein Vpu Virion infectivity factor	O75475 O75531 P04585 P04591 P04618 P05919 P17096 P52294 P62937 P69723 P69726	BAF BANF1 BCRG1 CYPA DFS70 HMGA1 HMGIY KPNA1 LEDGF PPIA PSIP1 PSIP2 RCH2 gag gag-pol rev vif vpr vpu	Homo sapiens (human)
2-LTR circle formation	Barrier-to-autointegration factor DNA ligase 4 DNA repair protein XRCC4 Gag polyprotein Gag-Pol polyprotein High mobility group protein HMG-I/HMG-Y PC4 and SFRS1-interacting protein Protein Rev Protein Vpr Protein Vpu Virion infectivity factor X-ray repair cross-complementing protein 5 X-ray repair cross-complementing protein 6	O75475 O75531 P04585 P04591 P04618 P05919 P12956 P13010 P17096 P49917 P69723 P69726 Q13426	BAF BANF1 BCRG1 DFS70 G22P1 G22P2 HMGA1 HMGIY LEDGF LIG4 PSIP1 PSIP2 XRCC4 XRCC5 XRCC6 gag gag-pol rev vif vpr vpu	Homo sapiens (human)
IRE1alpha activates chaperones	Endoplasmic reticulum chaperone BiP Serine/threonine-protein kinase/endoribonuclease IRE1	O75460 P11021	ERN1 GRP78 HSPA5 IRE1	Homo sapiens (human)
Processing of SMDT1	ATP-dependent zinc metalloprotease YME1L1 Calcium uniporter protein, mitochondrial Calcium uniporter regulatory subunit MCUb, mitochondrial Calcium uptake protein 1, mitochondrial Calcium uptake protein 2, mitochondrial Calcium uptake protein 3, mitochondrial Essential MCU regulator, mitochondrial Mitochondrial inner membrane m-AAA protease component AFG3L2 Mitochondrial inner membrane m-AAA protease component paraplegin Mitochondrial-processing peptidase subunit alpha Mitochondrial-processing peptidase subunit beta Presenilin-associated rhomboid-like protein, mitochondrial Prohibitin 1 Prohibitin-2 Stomatin-like protein 2, mitochondrial m-AAA protease-interacting protein 1, mitochondrial	O75439 P35232 Q10713 Q86XE3 Q8IYU8 Q8NE86 Q8WWC4 Q96TA2 Q99623 Q9BPX6 Q9H300 Q9H4I9 Q9NWR8 Q9UJZ1 Q9UQ90 Q9Y4W6	AFG3L2 BAP C10orf42 C22orf32 C2orf47 CALC CAR CBARA1 CCDC109A CCDC109B CMAR EFHA1 EFHA2 EMRE FTSH1 INPP5E KIAA0123 MAIP1 MCU MCUB MICU1 MICU2 MICU3 MPPA MPPB PARL PGN PHB PHB1 PHB2 PMPCA PMPCB PSARL REA SLP2 SMDT1 SPG7 STOML2 YME1L YME1L1	Homo sapiens (human)
Cristae formation	ATP synthase F(0) complex subunit B1, mitochondrial ATP synthase F(0) complex subunit C1, mitochondrial ATP synthase F(0) complex subunit C2, mitochondrial ATP synthase F(0) complex subunit C3, mitochondrial ATP synthase protein 8 ATP synthase subunit O, mitochondrial ATP synthase subunit a ATP synthase subunit alpha, mitochondrial ATP synthase subunit beta, mitochondrial ATP synthase subunit d, mitochondrial ATP synthase subunit delta, mitochondrial ATP synthase subunit e, mitochondrial ATP synthase subunit epsilon, mitochondrial ATP synthase subunit f, mitochondrial ATP synthase subunit g, mitochondrial ATP synthase subunit gamma, mitochondrial ATP synthase subunit s, mitochondrial ATP synthase-coupling factor 6, mitochondrial DnaJ homolog subfamily C member 11 MICOS complex subunit MIC10 MICOS complex subunit MIC13 MICOS complex subunit MIC19 MICOS complex subunit MIC25 MICOS complex subunit MIC26 MICOS complex subunit MIC27 MICOS complex subunit MIC60 Metaxin-1 Metaxin-2 Sorting and assembly machinery component 50 homolog Stress-70 protein, mitochondrial Transmembrane protein 11, mitochondrial	O75431 O75947 O75964 P00846 P03928 P05496 P06576 P17152 P18859 P24539 P25705 P30049 P36542 P38646 P48047 P48201 P56134 P56381 P56385 Q06055 Q13505 Q16891 Q5TGZ0 Q5XKP0 Q6UXV4 Q99766 Q9BRQ6 Q9BUR5 Q9NVH1 Q9NX63 Q9Y512	APOO APOOL ATP5A ATP5A1 ATP5AL2 ATP5B ATP5C ATP5C1 ATP5CL1 ATP5D ATP5E ATP5F1 ATP5F1A ATP5F1B ATP5F1C ATP5F1D ATP5F1E ATP5G1 ATP5G2 ATP5G3 ATP5H ATP5I ATP5J ATP5J2 ATP5JL ATP5K ATP5L ATP5MC1 ATP5MC2 ATP5MC3 ATP5ME ATP5MF ATP5MG ATP5O ATP5PB ATP5PD ATP5PF ATP5PO ATP5S ATP6 ATP8 ATPASE6 ATPASE8 ATPM ATPMB ATPO ATPSB ATPW C17orf35 C19orf70 C1orf151 CHCHD3 CHCHD6 CHCM1 CXorf33 DMAC2L DNAJC11 FAM121A FAM121B GRP75 HMP HSPA9 HSPA9B IMMT MIC10 MIC13 MIC19 MIC23 MIC25 MIC26 MIC27 MIC60 MICOS10 MICOS13 MINOS1 MINOS2 MINOS3 MT-ATP6 MT-ATP8 MTATP6 MTATP8 MTX MTX1 MTX2 MTXN PM1 QIL1 SAM50 SAMM50 TMEM11 mt-HSP70	Homo sapiens (human)
Unwinding of DNA	Cell division control protein 45 homolog DNA helicase MCM8 DNA replication complex GINS protein PSF1 DNA replication complex GINS protein PSF2 DNA replication complex GINS protein PSF3 DNA replication complex GINS protein SLD5 DNA replication licensing factor MCM2 DNA replication licensing factor MCM3 DNA replication licensing factor MCM4 DNA replication licensing factor MCM5 DNA replication licensing factor MCM6 DNA replication licensing factor MCM7	O75419 P25205 P33991 P33992 P33993 P49736 Q14566 Q14691 Q9BRT9 Q9BRX5 Q9UJA3 Q9Y248	BM28 C20orf154 CCNL1 CDC21 CDC45 CDC45L CDC45L2 CDC46 CDC47 CDCL1 GINS1 GINS2 GINS3 GINS4 KIAA0030 KIAA0186 MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 MCM8 PSF1 PSF2 PSF3 SLD5	Homo sapiens (human)
G1/S-Specific Transcription	Cell division control protein 45 homolog Cell division control protein 6 homolog Cyclin-A1 Cyclin-dependent kinase 1 DNA polymerase alpha catalytic subunit DNA replication factor Cdt1 Dihydrofolate reductase F-box only protein 5 G1/S-specific cyclin-E1 Histone deacetylase 1 Histone-binding protein RBBP4 Origin recognition complex subunit 1 Proliferating cell nuclear antigen Protein lin-37 homolog Protein lin-52 homolog Protein lin-54 homolog Protein lin-9 homolog Retinoblastoma-like protein 1 Retinoblastoma-like protein 2 Ribonucleoside-diphosphate reductase subunit M2 Thymidine kinase, cytosolic Thymidylate synthase Transcription factor Dp-1 Transcription factor Dp-2 Transcription factor E2F1 Transcription factor E2F4 Transcription factor E2F5 Transcription factor E2F6	O75419 O75461 P00374 P04183 P04818 P06493 P09884 P12004 P24864 P28749 P31350 P78396 Q01094 Q08999 Q09028 Q13415 Q13547 Q14186 Q14188 Q15329 Q16254 Q52LA3 Q5TKA1 Q6MZP7 Q96GY3 Q99741 Q9H211 Q9UKT4	BARA C14orf46 CCNA1 CCNE CCNE1 CDC18L CDC2 CDC28A CDC45 CDC45L CDC45L2 CDC6 CDK1 CDKN1 CDT1 CXCDC1 DHFR DP1 DP2 E2F1 E2F4 E2F5 E2F6 EMI1 FBX5 FBXO5 HDAC1 KIAA2037 LIN37 LIN52 LIN54 LIN9 ORC1 ORC1L P34CDC2 PARC1 PCNA POLA POLA1 RB2 RBAP48 RBBP3 RBBP4 RBL1 RBL2 RPD3L1 RR2 RRM2 TFDP1 TFDP2 TGS TK1 TS TYMS	Homo sapiens (human)
Amino acid transport across the plasma membrane	Amino acid transporter heavy chain SLC3A1 Amino acid transporter heavy chain SLC3A2 Asc-type amino acid transporter 1 Cationic amino acid transporter 3 Cystine/glutamate transporter High affinity cationic amino acid transporter 1 Inactive sodium-dependent neutral amino acid transporter B(0)AT3 Large neutral amino acids transporter small subunit 1 Large neutral amino acids transporter small subunit 2 Large neutral amino acids transporter small subunit 3 Large neutral amino acids transporter small subunit 4 Mitochondrial basic amino acids transporter Monocarboxylate transporter 10 Neutral amino acid transporter A Neutral amino acid transporter B(0) Neutral amino acid uniporter 4 Proton-coupled amino acid transporter 1 Proton-coupled amino acid transporter 2 Sodium- and chloride-dependent betaine transporter Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+) Sodium- and chloride-dependent taurine transporter Sodium- and chloride-dependent transporter XTRP3 Sodium-coupled neutral amino acid symporter 1 Sodium-coupled neutral amino acid symporter 2 Sodium-coupled neutral amino acid transporter 3 Sodium-coupled neutral amino acid transporter 4 Sodium-coupled neutral amino acid transporter 5 Sodium-dependent neutral amino acid transporter B(0)AT1 Sodium-dependent neutral amino acid transporter B(0)AT2 Y+L amino acid transporter 1 Y+L amino acid transporter 2 b(0,+)-type amino acid transporter 1	O75387 P08195 P30825 P31641 P43007 P48065 P82251 Q01650 Q07837 Q15758 Q495M3 Q695T7 Q6YBV0 Q7Z2H8 Q8N370 Q8N8R3 Q8TF71 Q8WUX1 Q8WY07 Q92536 Q969I6 Q96N87 Q96QD8 Q99624 Q9H2H9 Q9H2J7 Q9NP91 Q9NS82 Q9UHI5 Q9UM01 Q9UN76 Q9UPY5	ASC1 ASCT1 ASCT2 ATA1 ATA2 ATA3 ATRC1 ATRC3 B0AT1 B0AT2 B0AT3 BAT1 BGT1 C14orf69 CAT3 CD98LC ERR G17 JM24 KIAA0245 KIAA1382 LAT1 LAT2 LAT3 LAT4 M7V1 MCT10 MDU1 MPE16 NAT1 NAT2 NAT3 NBAT NTT73 ORNT3 PAT1 PAT2 PAT4 PB39 POV1 RDR RDRC REC1L SAT1 SAT2 SATT SBAT1 SIT1 SLC16A10 SLC1A4 SLC1A5 SLC25A29 SLC36A1 SLC36A2 SLC36A4 SLC38A1 SLC38A2 SLC38A3 SLC38A4 SLC38A5 SLC3A1 SLC3A2 SLC43A1 SLC43A2 SLC6A12 SLC6A14 SLC6A15 SLC6A18 SLC6A19 SLC6A20 SLC6A6 SLC7A1 SLC7A10 SLC7A11 SLC7A3 SLC7A5 SLC7A6 SLC7A7 SLC7A8 SLC7A9 SN1 SN2 SNAT1 SNAT2 SNAT3 SNAT4 SNAT5 TAT1 TRAMD1 XT3 XTRP2 XTRP3	Homo sapiens (human)
TBC/RABGAPs	ADP-ribosylation factor 6 ADP-ribosylation factor-binding protein GGA1 ADP-ribosylation factor-binding protein GGA2 ADP-ribosylation factor-binding protein GGA3 Carabin Gamma-aminobutyric acid receptor-associated protein-like 2 Gamma-aminobutyric acid receptor-associated protein Genome polyprotein Hamartin Microtubule-associated proteins 1A/1B light chain 3B Optineurin Rab GTPase-activating protein 1 Rab GTPase-binding effector protein 1 Rab5 GDP/GTP exchange factor Ras-related protein Rab-11A Ras-related protein Rab-11B Ras-related protein Rab-33A Ras-related protein Rab-33B Ras-related protein Rab-35 Ras-related protein Rab-4A Ras-related protein Rab-5A Ras-related protein Rab-5B Ras-related protein Rab-5C Ras-related protein Rab-6A Ras-related protein Rab-6B Ras-related protein Rab-7a Ras-related protein Rab-7b Ras-related protein Rab-8A Ras-related protein Rab-8B Serine/threonine-protein kinase ULK1 Synaptotagmin-like protein 1 TBC1 domain family member 10A TBC1 domain family member 10B TBC1 domain family member 13 TBC1 domain family member 14 TBC1 domain family member 15 TBC1 domain family member 16 TBC1 domain family member 17 TBC1 domain family member 20 TBC1 domain family member 24 TBC1 domain family member 25 TBC1 domain family member 2A TBC1 domain family member 3 TBC1 domain family member 7 Tuberin	O75385 O95166 P20338 P20339 P20340 P27958 P49815 P51148 P51149 P60520 P61006 P61020 P62330 P62491 Q14088 Q15276 Q15286 Q15907 Q3MII6 Q4KMP7 Q8IV04 Q8IYJ3 Q8IZP1 Q8TBP0 Q8TC07 Q92574 Q92930 Q96AH8 Q96BZ9 Q96CV9 Q9BXI6 Q9BYX2 Q9GZQ8 Q9H082 Q9HA65 Q9NRW1 Q9NVG8 Q9NZ52 Q9P0N9 Q9P2M4 Q9UJ41 Q9UJY4 Q9UJY5 Q9ULP9 Q9Y3P9	ARF6 C20orf140 EPI64 FIP2 FLC3A FLC3B GABARAP GABARAPL2 GEF2 GGA1 GGA2 GGA3 GLC1E HIP7 HYPL KIAA0154 KIAA0243 KIAA0722 KIAA1080 KIAA1171 KIAA1322 MAP1ALC3 MAP1LC3B MEL NRP OATL1 OPTN PARIS1 PP8997 PRC17 RAB11 RAB11A RAB11B RAB1C RAB33A RAB33B RAB35 RAB4 RAB4A RAB5 RAB5A RAB5B RAB5C RAB5EP RAB6 RAB6A RAB6B RAB7 RAB7A RAB7B RAB8 RAB8A RAB8B RABEP1 RABEX5 RABGAP1 RABGEF1 RABL RABPT5 RABPT5A RABS10 RAY SLP1 SYTL1 TBC1D10 TBC1D10A TBC1D10B TBC1D10C TBC1D13 TBC1D14 TBC1D15 TBC1D16 TBC1D17 TBC1D2 TBC1D20 TBC1D24 TBC1D25 TBC1D2A TBC1D3 TBC1D3A TBC1D7 TBC7 TSC TSC1 TSC2 TSC4 ULK1 YPT3	Homo sapiens (human)
Receptor Mediated Mitophagy	Autophagy protein 5 Casein kinase II subunit alpha' Casein kinase II subunit alpha Casein kinase II subunit beta FUN14 domain-containing protein 1 Microtubule-associated proteins 1A/1B light chain 3A Microtubule-associated proteins 1A/1B light chain 3B Serine/threonine-protein kinase ULK1 Ubiquitin-like protein ATG12	O75385 O94817 P19784 P67870 P68400 Q8IVP5 Q9GZQ8 Q9H1Y0 Q9H492	APG12 APG12L APG5L ASP ATG12 ATG5 CK2A1 CK2A2 CK2N CSNK2A1 CSNK2A2 CSNK2B FUNDC1 G5A KIAA0722 MAP1ALC3 MAP1LC3A MAP1LC3B ULK1	Homo sapiens (human)
LXRs regulate gene expression to control bile acid homeostasis	Gastrotropin Nuclear receptor coactivator 1 Nuclear receptor corepressor 1 Nuclear receptor corepressor 2 Oxysterols receptor LXR-alpha Oxysterols receptor LXR-beta Retinoic acid receptor RXR-alpha Retinoic acid receptor RXR-beta UDP-glucuronosyltransferase 1A3	O75376 P19793 P28702 P35503 P51161 P55055 Q13133 Q15788 Q9Y618	BHLHE74 CTG26 FABP6 GNT1 ILBP ILLBP KIAA1047 LXRA LXRB NCOA1 NCOR1 NCOR2 NER NR1H2 NR1H3 NR2B1 NR2B2 RXRA RXRB SRC1 UGT1 UGT1A3 UNR	Homo sapiens (human)
Nuclear Receptor transcription pathway	Androgen receptor COUP transcription factor 1 Estrogen receptor beta Estrogen receptor Estrogen-related receptor gamma Hepatocyte nuclear factor 4-alpha Hepatocyte nuclear factor 4-gamma Mediator of RNA polymerase II transcription subunit 1 Nuclear receptor 2C2-associated protein Nuclear receptor ROR-alpha Nuclear receptor ROR-beta Nuclear receptor ROR-gamma Nuclear receptor corepressor 1 Nuclear receptor corepressor 2 Nuclear receptor subfamily 0 group B member 2 Nuclear receptor subfamily 1 group D member 1 Nuclear receptor subfamily 1 group D member 2 Nuclear receptor subfamily 2 group C member 1 Nuclear receptor subfamily 2 group C member 2 Nuclear receptor subfamily 2 group E member 1 Nuclear receptor subfamily 2 group F member 6 Nuclear receptor subfamily 4 group A member 2 Nuclear receptor subfamily 4immunitygroup A member 1 Nuclear receptor-binding protein Oxysterols receptor LXR-beta Peroxisome proliferator-activated receptor alpha Peroxisome proliferator-activated receptor delta Peroxisome proliferator-activated receptor gamma Progesterone receptor Retinoic acid receptor RXR-alpha Retinoic acid receptor RXR-beta Retinoic acid receptor RXR-gamma Retinoic acid receptor alpha Retinoic acid receptor beta Retinoic acid receptor gamma Steroid hormone receptor ERR1 Steroid hormone receptor ERR2 Steroidogenic factor 1 Thyroid hormone receptor alpha Thyroid hormone receptor beta Vitamin D3 receptor	O75376 O95718 P03372 P06401 P10275 P10276 P10588 P10589 P10826 P10827 P10828 P11473 P11474 P13056 P13631 P19793 P20393 P22736 P28702 P35398 P37231 P41235 P43354 P48443 P49116 P51449 P55055 P62508 Q03181 Q07869 Q13285 Q14541 Q14995 Q15466 Q15648 Q86WQ0 Q92731 Q92753 Q9UHY1 Q9Y466 Q9Y618	AD4BP AR ARC205 BCON3 CRSP1 CRSP200 CTG26 DHTR DRIP205 DRIP230 EAR1 EAR2 EAR3 EAR7 ERBA1 ERBA2 ERBAL2 ERBAL3 ERR1 ERR3 ERRB2 ERRG2 ESR ESR1 ESR2 ESRL1 ESRL2 ESRRA ESRRB ESRRG ESTRB FTZF1 GFRP1 HAP HMR HNF4 HNF4A HNF4G HREV KIAA0832 KIAA1047 LXRB MED1 NAK1 NCOR1 NCOR2 NER NOT NR0B2 NR1A1 NR1A2 NR1B1 NR1B2 NR1B3 NR1C1 NR1C2 NR1C3 NR1D1 NR1D2 NR1F1 NR1F2 NR1F3 NR1H2 NR1I1 NR2A1 NR2A2 NR2B1 NR2B2 NR2B3 NR2C1 NR2C2 NR2C2AP NR2E1 NR2F1 NR2F6 NR3A1 NR3A2 NR3B1 NR3B2 NR3B3 NR3C3 NR3C4 NR4A1 NR4A2 NR5A1 NRBP NRBP1 NURR1 PBP PGR PPAR PPARA PPARB PPARBP PPARD PPARG PPARGBP RARA RARB RARG RB18A RORA RORB RORC RORG RXRA RXRB RXRG RZRA RZRB RZRG SF1 SHP TAK1 TCF14 TFCOUP1 THR1 THRA THRA1 THRA2 THRAL THRB TINUR TLX TR2 TR4 TRA16 TRAP220 TRIP2 UNR VDR	Homo sapiens (human)
Phosphate bond hydrolysis by NTPDase proteins	Ectonucleoside triphosphate diphosphohydrolase 1 Ectonucleoside triphosphate diphosphohydrolase 2 Ectonucleoside triphosphate diphosphohydrolase 3 Ectonucleoside triphosphate diphosphohydrolase 4 Ectonucleoside triphosphate diphosphohydrolase 6 Ectonucleoside triphosphate diphosphohydrolase 7 Ectonucleoside triphosphate diphosphohydrolase 8 Nucleoside diphosphate phosphatase ENTPD5	O75354 O75355 O75356 P49961 Q5MY95 Q9NQZ7 Q9Y227 Q9Y5L3	CD39 CD39L1 CD39L2 CD39L3 CD39L4 ENTPD1 ENTPD2 ENTPD3 ENTPD4 ENTPD5 ENTPD6 ENTPD7 ENTPD8 IL6ST2 KIAA0392 LALP1 LALP70 LYSAL1 PCPH	Homo sapiens (human)
Defective MPDU1 causes CDG-1f	Mannose-P-dolichol utilization defect 1 protein	O75352	MPDU1	Homo sapiens (human)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein	Alpha-1,2-mannosyltransferase ALG9 Alpha-1,3/1,6-mannosyltransferase ALG2 Chitobiosyldiphosphodolichol beta-mannosyltransferase Dol-P-Glc Dol-P-Glc Dol-P-Man Dol-P-Man Dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase GDP-Man Man(5)GlcNAc(2)-PP-dolichol translocation protein RFT1 Mannose-P-dolichol utilization defect 1 protein UDP-N-acetylglucosamine transferase subunit ALG13 UDP-N-acetylglucosamine transferase subunit ALG14 UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase	O75352 Q2TAA5 Q5BKT4 Q5I7T1 Q92685 Q96AA3 Q96F25 Q9BT22 Q9BV10 Q9BVK2 Q9H3H5 Q9H553 Q9H6U8 Q9NP73 Q9Y672	ALG1 ALG10 ALG10A ALG10B ALG11 ALG12 ALG13 ALG14 ALG2 ALG3 ALG6 ALG8 ALG9 CXorf45 DIBD1 DPAGT1 DPAGT2 GLT28D1 GT8 HMAT1 HMT1 KCR1 MPDU1 NOT NOT56L RFT1	Homo sapiens (human)
Nitric oxide stimulates guanylate cyclase	Guanylate cyclase soluble subunit alpha-1 Guanylate cyclase soluble subunit alpha-2 Guanylate cyclase soluble subunit beta-1 Guanylate cyclase soluble subunit beta-2 Nitric oxide synthase 1 Nitric oxide synthase 3 Nitric oxide synthase, inducible	O75343 P29474 P29475 P33402 P35228 Q02108 Q02153	GUC1A2 GUC1A3 GUC1B3 GUCSA2 GUCSA3 GUCSB3 GUCY1A1 GUCY1A2 GUCY1A3 GUCY1B1 GUCY1B2 GUCY1B3 NOS1 NOS2 NOS2A NOS3	Homo sapiens (human)
Synthesis of 12-eicosatetraenoic acid derivatives	Arachidonate 12-lipoxygenase, 12R-type Glutathione peroxidase 1 Glutathione peroxidase 2 Hydroperoxide isomerase ALOXE3 Phospholipid hydroperoxide glutathione peroxidase GPX4 Polyunsaturated fatty acid lipoxygenase ALOX12 Polyunsaturated fatty acid lipoxygenase ALOX15	O75342 P07203 P16050 P18054 P18283 P36969 Q9BYJ1	12LO ALOX12 ALOX12B ALOX15 ALOXE3 GPX1 GPX2 GPX4 LOG12 LOG15	Homo sapiens (human)
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)	Cartilage intermediate layer protein 1 Insulin-like growth factor 1 receptor Insulin-like growth factor I Insulin-like growth factor II	O75339 P01344 P05019 P08069	CILP IBP1 IGF1 IGF1R IGF2	Homo sapiens (human)
Ubiquinol biosynthesis	2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial 4-hydroxybenzoate polyprenyltransferase, mitochondrial 5-demethoxyubiquinone hydroxylase, mitochondrial All trans-polyprenyl-diphosphate synthase PDSS1 All trans-polyprenyl-diphosphate synthase PDSS2 Atypical kinase COQ8A, mitochondrial Atypical kinase COQ8B, mitochondrial Ubiquinone biosynthesis O-methyltransferase, mitochondrial Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial Ubiquinone biosynthesis protein COQ9, mitochondrial	O75208 Q5HYK3 Q5T2R2 Q86YH6 Q8NI60 Q96D53 Q96H96 Q99807 Q9NZJ6 Q9Y2Z9 Q9Y3A0	ADCK3 ADCK4 C16orf49 C6orf210 CABC1 CL640 COQ2 COQ3 COQ4 COQ5 COQ6 COQ7 COQ8A COQ8B COQ9 DLP1 DPS1 PDSS1 PDSS2 TPRT	Homo sapiens (human)
Signaling by LRP5 mutants	Dickkopf-related protein 1 Dickkopf-related protein 2 Dickkopf-related protein 4 Kremen protein 1 Kremen protein 2 Low-density lipoprotein receptor-related protein 5	O75197 O94907 Q8NCW0 Q96MU8 Q9UBT3 Q9UBU2	DKK1 DKK2 DKK4 KREMEN KREMEN1 KREMEN2 KRM1 KRM2 LR3 LRP5 LRP7	Homo sapiens (human)
Formation of xylulose-5-phosphate	Aldo-keto reductase family 1 member A1 L-xylulose reductase Lambda-crystallin homolog Sorbitol dehydrogenase Xylulose kinase	O75191 P14550 Q00796 Q7Z4W1 Q9Y2S2	AKR1A1 ALDR1 ALR CRY CRYL1 DCXR SDR20C1 SORD XYLB	Homo sapiens (human)
Receptor-type tyrosine-protein phosphatases	Interleukin-1 receptor accessory protein-like 1 Leucine-rich repeat-containing protein 4B Liprin-alpha-1 Liprin-alpha-2 Liprin-alpha-3 Liprin-alpha-4 Liprin-beta-1 Liprin-beta-2 NT-3 growth factor receptor Receptor-type tyrosine-protein phosphatase F Receptor-type tyrosine-protein phosphatase S Receptor-type tyrosine-protein phosphatase delta SLIT and NTRK-like protein 1 SLIT and NTRK-like protein 2 SLIT and NTRK-like protein 3 SLIT and NTRK-like protein 4 SLIT and NTRK-like protein 5 SLIT and NTRK-like protein 6 X-linked interleukin-1 receptor accessory protein-like 2	O75145 O75334 O75335 O94933 O94991 P10586 P23468 Q13136 Q13332 Q16288 Q86W92 Q8IW52 Q8ND30 Q96PX8 Q9H156 Q9H5Y7 Q9NP60 Q9NT99 Q9NZN1	CXorf2 IL1R9 IL1RAPL1 IL1RAPL2 KIAA0654 KIAA0848 KIAA0897 KIAA0918 KIAA1230 KIAA1854 KIAA1910 LAR LIP1 LRIG4 LRRC11 LRRC12 LRRC4B NTRK3 OPHN4 PPFIA1 PPFIA2 PPFIA3 PPFIA4 PPFIBP1 PPFIBP2 PTPRD PTPRF PTPRS SLITL1 SLITRK1 SLITRK2 SLITRK3 SLITRK4 SLITRK5 SLITRK6 TRKC	Homo sapiens (human)
Glycerophospholipid biosynthesis	Acylglycerol kinase, mitochondrial Copine-1 Copine-3 Copine-6 Copine-7	O75131 O95741 Q53H12 Q99829 Q9UBL6	AGK CPN1 CPN3 CPNE1 CPNE3 CPNE6 CPNE7 KIAA0636 MULK	Homo sapiens (human)
Role of ABL in ROBO-SLIT signaling	Adenylyl cyclase-associated protein 1 Adenylyl cyclase-associated protein 2 CLIP-associating protein 1 CLIP-associating protein 2 Roundabout homolog 1 Slit homolog 2 protein Tyrosine-protein kinase ABL1 Tyrosine-protein kinase ABL2	O75122 O94813 P00519 P40123 P42684 Q01518 Q7Z460 Q9Y6N7	ABL ABL1 ABL2 ABLL ARG CAP CAP1 CAP2 CLASP1 CLASP2 DUTT1 JTK7 KIAA0622 KIAA0627 MAST1 ROBO1 SLIL3 SLIT2	Homo sapiens (human)

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