GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **1051 - 1075** of **2090** in total

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Pathway Name	Protein Name	UniProt ID ▼	Gene Symbol	Organism	GlyTouCan ID
Impaired BRCA2 binding to RAD51	26S proteasome complex subunit SEM1 ATR-interacting protein BRCA1-associated RING domain protein 1 Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN Breast cancer type 1 susceptibility protein Breast cancer type 2 susceptibility protein Cell cycle checkpoint control protein RAD9A Cell cycle checkpoint control protein RAD9B Cell cycle checkpoint protein RAD17 Cell cycle checkpoint protein RAD1 Checkpoint protein HUS1 DNA endonuclease RBBP8 DNA repair protein RAD50 DNA repair protein RAD51 homolog 1 DNA replication ATP-dependent helicase/nuclease DNA2 DNA topoisomerase 2-binding protein 1 DNA topoisomerase 3-alpha Double-strand break repair protein MRE11 Exonuclease 1 Fanconi anemia group J protein Histone acetyltransferase KAT5 Nibrin RAD9, HUS1, RAD1-interacting nuclear orphan protein 1 RecQ-like DNA helicase BLM RecQ-mediated genome instability protein 1 RecQ-mediated genome instability protein 2 Replication factor C subunit 2 Replication factor C subunit 3 Replication factor C subunit 4 Replication factor C subunit 5 Replication protein A 14 kDa subunit Replication protein A 32 kDa subunit Replication protein A 70 kDa DNA-binding subunit Serine-protein kinase ATM Serine/threonine-protein kinase ATR	O60671 O60921 O60934 O75943 P15927 P27694 P35244 P35249 P35250 P38398 P40937 P40938 P49959 P51530 P51587 P54132 P60896 Q06609 Q13315 Q13472 Q13535 Q14191 Q6WBX8 Q8WXE1 Q92547 Q92878 Q92993 Q96E14 Q99638 Q99708 Q99728 Q9BSD3 Q9BX63 Q9H9A7 Q9UQ84	AGS1 ATM ATR ATRIP BACH1 BARD1 BLM BRCA1 BRCA2 BRIP1 C12orf32 C16orf75 C7orf76 C9orf76 CTIP DNA2 DNA2L DSS1 EXO1 EXOI FACD FANCD1 FANCJ FRP1 HEX1 HNGS1 HTATIP HUS1 KAT5 KIAA0083 KIAA0259 MRE11 MRE11A NBN NBS NBS1 P95 R24L RAD1 RAD17 RAD50 RAD51 RAD51A RAD9A RAD9B RBBP8 REC1 RECA RECQ2 RECQ3 RECQL2 RECQL3 REPA1 REPA2 REPA3 RFC2 RFC3 RFC4 RFC5 RHINO RHNO1 RMI1 RMI2 RNF53 RPA1 RPA14 RPA2 RPA3 RPA32 RPA34 RPA70 SEM1 SHFDG1 SHFM1 TIP60 TOP3 TOP3A TOPBP1 WRN	Homo sapiens (human)
HDR through Single Strand Annealing (SSA)	ATR-interacting protein BRCA1-associated RING domain protein 1 Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN Breast cancer type 1 susceptibility protein Cell cycle checkpoint control protein RAD9A Cell cycle checkpoint control protein RAD9B Cell cycle checkpoint protein RAD17 Cell cycle checkpoint protein RAD1 Checkpoint protein HUS1 DNA endonuclease RBBP8 DNA excision repair protein ERCC-1 DNA repair endonuclease XPF DNA repair protein RAD50 DNA repair protein RAD51 homolog 1 DNA repair protein RAD52 homolog DNA replication ATP-dependent helicase/nuclease DNA2 DNA topoisomerase 2-binding protein 1 DNA topoisomerase 3-alpha Double-strand break repair protein MRE11 Exonuclease 1 Fanconi anemia group J protein Histone acetyltransferase KAT5 Nibrin RAD9, HUS1, RAD1-interacting nuclear orphan protein 1 RecQ-like DNA helicase BLM RecQ-mediated genome instability protein 1 RecQ-mediated genome instability protein 2 Replication factor C subunit 2 Replication factor C subunit 3 Replication factor C subunit 4 Replication factor C subunit 5 Replication protein A 14 kDa subunit Replication protein A 32 kDa subunit Replication protein A 70 kDa DNA-binding subunit Serine-protein kinase ATM Serine/threonine-protein kinase ATR Tyrosine-protein kinase ABL1	O60671 O60921 O60934 O75943 P00519 P07992 P15927 P27694 P35244 P35249 P35250 P38398 P40937 P40938 P43351 P49959 P51530 P54132 Q06609 Q13315 Q13472 Q13535 Q14191 Q6WBX8 Q8WXE1 Q92547 Q92878 Q92889 Q92993 Q96E14 Q99638 Q99708 Q99728 Q9BSD3 Q9BX63 Q9H9A7 Q9UQ84	ABL ABL1 AGS1 ATM ATR ATRIP BACH1 BARD1 BLM BRCA1 BRIP1 C12orf32 C16orf75 C9orf76 CTIP DNA2 DNA2L ERCC1 ERCC11 ERCC4 EXO1 EXOI FANCJ FRP1 HEX1 HNGS1 HTATIP HUS1 JTK7 KAT5 KIAA0083 KIAA0259 MRE11 MRE11A NBN NBS NBS1 P95 R24L RAD1 RAD17 RAD50 RAD51 RAD51A RAD52 RAD9A RAD9B RBBP8 REC1 RECA RECQ2 RECQ3 RECQL2 RECQL3 REPA1 REPA2 REPA3 RFC2 RFC3 RFC4 RFC5 RHINO RHNO1 RMI1 RMI2 RNF53 RPA1 RPA14 RPA2 RPA3 RPA32 RPA34 RPA70 TIP60 TOP3 TOP3A TOPBP1 WRN XPF	Homo sapiens (human)
Chaperone Mediated Autophagy	ADP-ribosylation factor-like protein 13B Centrin-1 Cystic fibrosis transmembrane conductance regulator Elongation factor 1-alpha 1 Glial fibrillary acidic protein Heat shock cognate 71 kDa protein Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Hemoglobin subunit beta Histone deacetylase 6 Intraflagellar transport protein 88 homolog Lysosome-associated membrane glycoprotein 2 Parkinson disease protein 7 Pericentrin Perilipin-2 Perilipin-3 Polyubiquitin-B Polyubiquitin-C Ribonuclease pancreatic Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O60664 O95613 P07900 P07998 P08238 P0CG47 P0CG48 P11142 P13473 P13569 P14136 P62979 P62987 P68104 P68871 Q12798 Q13099 Q3SXY8 Q99497 Q99541 Q9UBN7	ABCC7 ADFP ARL13B ARL2L1 CEN1 CETN CETN1 CFTR EEF1A EEF1A1 EF1A GFAP HBB HDAC6 HSC70 HSP73 HSP90A HSP90AA1 HSP90AB1 HSP90B HSPA10 HSPA8 HSPC1 HSPC2 HSPC3 HSPCA HSPCB IFT88 KIAA0402 KIAA0901 LAMP2 LENG7 M6PRBP1 PARK7 PCNT PCNT2 PLIN2 PLIN3 RIB1 RNASE1 RNS1 RPS27A TG737 TIP47 TTC10 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Homo sapiens (human)
Glucuronidation	Palmitoyl-protein thioesterase ABHD10, mitochondrial UDP-glucuronosyltransferase 1-6 UDP-glucuronosyltransferase 1A10 UDP-glucuronosyltransferase 1A1 UDP-glucuronosyltransferase 1A3 UDP-glucuronosyltransferase 1A4 UDP-glucuronosyltransferase 1A5 UDP-glucuronosyltransferase 1A7 UDP-glucuronosyltransferase 1A8 UDP-glucuronosyltransferase 1A9 UDP-glucuronosyltransferase 2A1 UDP-glucuronosyltransferase 2A2 UDP-glucuronosyltransferase 2A3 UDP-glucuronosyltransferase 2B10 UDP-glucuronosyltransferase 2B11 UDP-glucuronosyltransferase 2B15 UDP-glucuronosyltransferase 2B17 UDP-glucuronosyltransferase 2B28 UDP-glucuronosyltransferase 2B4 UDP-glucuronosyltransferase 2B7 UDP-glucuronosyltransferase 3A1 UDP-glucuronosyltransferase 3A2	O60656 O75310 O75795 P06133 P0DTE4 P0DTE5 P16662 P19224 P22309 P22310 P35503 P35504 P36537 P54855 Q3SY77 Q6NUS8 Q6UWM9 Q9BY64 Q9HAW7 Q9HAW8 Q9HAW9 Q9NUJ1	ABHD10 GNT1 UGT1 UGT1A1 UGT1A10 UGT1A3 UGT1A4 UGT1A5 UGT1A6 UGT1A7 UGT1A8 UGT1A9 UGT2A1 UGT2A2 UGT2A3 UGT2B10 UGT2B11 UGT2B15 UGT2B17 UGT2B28 UGT2B4 UGT2B7 UGT2B8 UGT3A1 UGT3A2 UGTB2B9	Homo sapiens (human)
Regulation of MITF-M dependent genes involved in invasion	Carcinoembryonic antigen-related cell adhesion molecule 1 GMP reductase 1 Protein diaphanous homolog 1	O60610 P13688 P36959	BGP BGP1 CEACAM1 DIAP1 DIAPH1 GMPR GMPR1	Homo sapiens (human)
Toll Like Receptor TLR1:TLR2 Cascade	Major outer membrane protein P.IB Monocyte differentiation antigen CD14 Toll-like receptor 1 Toll-like receptor 2	O60603 P08571 P30690 Q15399	CD14 KIAA0012 TIL4 TLR1 TLR2 porB	Homo sapiens (human)
Toll Like Receptor TLR6:TLR2 Cascade	Monocyte differentiation antigen CD14 Peptidyl-prolyl cis-trans isomerase Mip Platelet glycoprotein 4 Toll-like receptor 2 Toll-like receptor 6	O60603 P08571 P16671 P26623 Q9Y2C9	CD14 CD36 GP3B GP4 TIL4 TLR2 TLR6 mip	Homo sapiens (human)
Toll Like Receptor 5 (TLR5) Cascade	Flagellin Toll-like receptor 5	O60602 P04949	TIL3 TLR5 flaF fliC hag	Homo sapiens (human)
MyD88 deficiency (TLR5)	Flagellin Myeloid differentiation primary response protein MyD88 Toll-like receptor 5	O60602 P04949 Q99836	MYD88 TIL3 TLR5 flaF fliC hag	Homo sapiens (human)
IRAK4 deficiency (TLR5)	Flagellin Interleukin-1 receptor-associated kinase 4 Myeloid differentiation primary response protein MyD88 Toll-like receptor 10 Toll-like receptor 5	O60602 P04949 Q99836 Q9BXR5 Q9NWZ3	IRAK4 MYD88 TIL3 TLR10 TLR5 flaF fliC hag	Homo sapiens (human)
Interactions of Tat with host cellular proteins	Cyclin-T1 Cyclin-dependent kinase 9 Protein Tat	O60563 P04608 P50750	CCNT1 CDC2L4 CDK9 TAK tat	Homo sapiens (human)
Transcriptional regulation of brown and beige adipocyte differentiation by EBF2	Bone morphogenetic protein 7 Chromodomain-helicase-DNA-binding protein 3 Chromodomain-helicase-DNA-binding protein 4 Cytochrome c oxidase subunit 7A1, mitochondrial Heterogeneous nuclear ribonucleoprotein U Histone deacetylase 1 Histone deacetylase 2 Histone-binding protein RBBP4 Histone-binding protein RBBP7 Histone-lysine N-methyltransferase PRDM16 Lipid transferase CIDEA Metastasis-associated protein MTA1 Metastasis-associated protein MTA2 Metastasis-associated protein MTA3 Methyl-CpG-binding domain protein 3 Mitochondrial brown fat uncoupling protein 1 Mothers against decapentaplegic homolog 1 Mothers against decapentaplegic homolog 4 Nuclear receptor coactivator 1 Peroxisome proliferator-activated receptor alpha Peroxisome proliferator-activated receptor gamma coactivator 1-alpha Peroxisome proliferator-activated receptor gamma coactivator 1-beta Peroxisome proliferator-activated receptor gamma Retinoic acid receptor RXR-alpha Transcription factor COE2 Transcriptional repressor p66-alpha Transcriptional repressor p66-beta Type II iodothyronine deiodinase Very long chain fatty acid elongase 3 Zinc finger protein 423	O60543 O94776 O95983 P18075 P19793 P24310 P25874 P37231 Q00839 Q07869 Q09028 Q12873 Q13330 Q13485 Q13547 Q14839 Q15788 Q15797 Q16576 Q2M1K9 Q86YN6 Q86YP4 Q8WXI9 Q92769 Q92813 Q9BTC8 Q9HAK2 Q9HAZ2 Q9HB03 Q9UBK2	BHLHE74 BMP7 BSP1 C1orf199 CHD3 CHD4 CIDEA CIG30 COE2 COX7A1 COX7AH DIO2 DPC4 EBF2 ELOVL3 GATAD2A GATAD2B HDAC1 HDAC2 HNRNPU HNRPU ITDI2 KIAA0760 KIAA1150 KIAA1266 KIAA1675 LEM6 MADH1 MADH4 MADR1 MBD3 MEL1 MTA1 MTA1L1 MTA2 MTA3 NCOA1 NPHP14 NR1C1 NR1C3 NR2B1 OAZ OP1 PERC PFM13 PGC1 PGC1A PGC1B PID PPAR PPARA PPARG PPARGC1 PPARGC1A PPARGC1B PRDM16 RBAP46 RBAP48 RBBP4 RBBP7 RPD3L1 RXRA SAFA SLC25A7 SMAD1 SMAD4 SRC1 TXDI2 U21.1 UCP UCP1 ZNF423	Homo sapiens (human)
Defective F8 sulfation at Y1699	Coagulation factor VIII Protein-tyrosine sulfotransferase 1 Protein-tyrosine sulfotransferase 2	O60507 O60704 P00451	F8 F8C TPST1 TPST2	Homo sapiens (human)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation	Coagulation factor VIII Fructosamine-3-kinase Ketosamine-3-kinase Protein-S-isoprenylcysteine O-methyltransferase Protein-tyrosine sulfotransferase 1 Protein-tyrosine sulfotransferase 2	O60507 O60704 O60725 P00451 Q9H479 Q9HA64	F8 F8C FN3K FN3KRP ICMT PCCMT TPST1 TPST2	Homo sapiens (human)
Defective AMN causes MGA1	Cobalamin binding intrinsic factor Cubilin Protein amnionless	O60494 P27352 Q9BXJ7	AMN CBLIF CUBN GIF IFCR IFMH	Homo sapiens (human)
Defective CUBN causes MGA1	Cobalamin binding intrinsic factor Cubilin Protein amnionless	O60494 P27352 Q9BXJ7	AMN CBLIF CUBN GIF IFCR IFMH	Homo sapiens (human)
HDL clearance	Apolipoprotein A-I Cubilin Protein amnionless Vigilin	O60494 P02647 Q00341 Q9BXJ7	AMN APOA1 CUBN HBP HDLBP IFCR VGL	Homo sapiens (human)
Intracellular metabolism of fatty acids regulates insulin secretion	Fatty acid CoA ligase Acsl3 Long-chain-fatty-acid--CoA ligase 4 Platelet glycoprotein 4	O60488 O95573 P16671	ACS3 ACS4 ACSL3 ACSL4 CD36 FACL3 FACL4 GP3B GP4 LACS3 LACS4	Homo sapiens (human)
POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation	Developmental pluripotency-associated protein 4 Ephrin type-A receptor 1 Fibroblast growth factor 2 Forkhead box protein D3 Homeobox protein NANOG POU domain, class 5, transcription factor 1 Protein Cripto Sal-like protein 1 Sal-like protein 4 Signal transducer and activator of transcription 3 Transcription factor SOX-2 Zinc finger protein ZIC 3	O60481 P09038 P13385 P21709 P40763 P48431 Q01860 Q7L190 Q9H9S0 Q9NSC2 Q9UJQ4 Q9UJU5	APRF CRIPTO CRIPTO-1 DPPA4 EPH EPHA1 EPHT EPHT1 FGF2 FGFB FOXD3 HFH2 NANOG OCT3 OCT4 OTF3 POU5F1 SAL1 SALL1 SALL4 SOX2 STAT3 TDGF1 ZIC3 ZNF203 ZNF794 ZNF797	Homo sapiens (human)
Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2	Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB Mannosyl-oligosaccharide 1,2-alpha-mannosidase IC	O60476 P33908 Q9NR34	MAN1A1 MAN1A2 MAN1A3 MAN1B MAN1C MAN1C1	Homo sapiens (human)	G70323CJ
DSCAM interactions	Cell adhesion molecule DSCAM Cell adhesion molecule DSCAML1 Netrin receptor DCC Netrin-1	O60469 O95631 P43146 Q8TD84	DCC DSCAM DSCAM2 DSCAML1 IGDCC1 KIAA1132 NTN1 NTN1L	Homo sapiens (human)
NrCAM interactions	Ankyrin-1 Contactin-2 Disks large homolog 1 Disks large homolog 3 Disks large homolog 4 Neuronal cell adhesion molecule Neuropilin-2	O60462 P16157 P78352 Q02246 Q12959 Q92796 Q92823	ANK ANK1 AXT CNTN2 DLG1 DLG3 DLG4 KIAA0343 KIAA1232 NRCAM NRP2 PSD95 TAG1 TAX1 VEGF165R2	Homo sapiens (human)
Release of apoptotic factors from the mitochondria	Apoptosis regulator BAX Bcl-2 homologous antagonist/killer Cytochrome c Diablo IAP-binding mitochondrial protein Gasdermin-D Gasdermin-E	O60443 P57764 P99999 Q07812 Q16611 Q9NR28	BAK BAK1 BAX BCL2L4 BCL2L7 CDN1 CYC CYCS DFNA5 DFNA5L DIABLO GSDMD GSDMDC1 GSDME ICERE1 SMAC	Homo sapiens (human)
Defective pyroptosis	DNA (cytosine-5)-methyltransferase 1 DNA (cytosine-5)-methyltransferase 3A DNA (cytosine-5)-methyltransferase 3B DNA polymerase alpha catalytic subunit DNA polymerase alpha subunit B DNA primase large subunit DNA primase small subunit Gasdermin-E Histone H2A type 1-B/E Histone H2A type 1-C Histone H2A type 1-D Histone H2A type 1-J Histone H2A type 2-A Histone H2A type 2-C Histone H2A-Bbd type 1 Histone H2A.J Histone H2A.V Histone H2AX Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/F/G/I Histone H2B type 1-D Histone H2B type 1-H Histone H2B type 1-J Histone H2B type 1-K Histone H2B type 1-L Histone H2B type 1-M Histone H2B type 1-N Histone H2B type 1-O Histone H2B type 2-E Histone H2B type 3-B Histone H2B type F-S Histone H3.1 Histone H3.2 Histone H3.3 Histone H4 Histone-binding protein RBBP4 Histone-binding protein RBBP7 Histone-lysine N-methyltransferase EZH2 Polycomb protein EED Polycomb protein SUZ12	O60443 O60814 O75530 P04908 P06899 P09884 P0C5Y9 P16104 P20671 P23527 P26358 P33778 P49642 P49643 P57053 P58876 P62805 P62807 P68431 P84243 Q09028 Q14181 Q15022 Q15910 Q16576 Q16777 Q16778 Q6FI13 Q71DI3 Q71UI9 Q8N257 Q93077 Q93079 Q96A08 Q99877 Q99878 Q99879 Q99880 Q9BTM1 Q9UBC3 Q9Y6K1	AIM CHET9 CXXC9 DFNA5 DNMT DNMT1 DNMT3A DNMT3B EED EZH2 GSDME H2AB1 H2AC14 H2AC18 H2AC19 H2AC20 H2AC4 H2AC6 H2AC7 H2AC8 H2AFA H2AFB1 H2AFE H2AFG H2AFJ H2AFL H2AFM H2AFO H2AFQ H2AFV H2AFX H2AJ H2AV H2AX H2AZ2 H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H2BFA H2BFB H2BFC H2BFD H2BFE H2BFF H2BFG H2BFH H2BFJ H2BFK H2BFL H2BFN H2BFQ H2BFR H2BFS H2BFT H2BS1 H2BU1 H3-3A H3-3B H3.3A H3.3B H3C1 H3C10 H3C11 H3C12 H3C13 H3C14 H3C15 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 H3F2 H3F3 H3F3A H3F3B H3FA H3FB H3FC HIST1H3C H3FD H3FF H3FH H3FI H3FJ H3FK H3FL H3FM H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HIRIP1 HIRIP2 HIST1H2AB HIST1H2AC HIST1H2AD HIST1H2AE HIST1H2AJ HIST1H2BA HIST1H2BB HIST1H2BC HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2BI HIST1H2BJ HIST1H2BK HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST1H3A HIST1H3B HIST1H3D HIST1H3E HIST1H3F HIST1H3G HIST1H3H HIST1H3I HIST1H3J HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H2AA HIST2H2AA3 HIST2H2AA4 HIST2H2AC HIST2H2BE HIST2H3A HIST2H3C HIST2H3D HIST2H4 HIST2H4A HIST2H4B HIST3H2BB HIST4H4 ICERE1 JJAZ1 KIAA0160 KMT6 POLA POLA1 POLA2 PRIM1 PRIM2 PRIM2A RBAP46 RBAP48 RBBP4 RBBP7 SUZ12 TSH2B	Homo sapiens (human)
Linoleic acid (LA) metabolism	ATP-binding cassette sub-family D member 1 Acyl-CoA (8-3)-desaturase Acyl-CoA 6-desaturase Long-chain-fatty-acid--CoA ligase 1 Very long chain fatty acid elongase 1 Very long chain fatty acid elongase 2 Very long chain fatty acid elongase 3 Very long chain fatty acid elongase 5	O60427 O95864 P33121 P33897 Q9BW60 Q9HB03 Q9NXB9 Q9NYP7	ABCD1 ACSL1 ALD CIG30 ELG3 ELOVL1 ELOVL2 ELOVL3 ELOVL5 FACL1 FACL2 FADS1 FADS2 FADSD5 LACS LACS1 LACS2 SSC1 SSC2	Homo sapiens (human)

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