GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **1376 - 1400** of **2090** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism
Endosomal/Vacuolar pathway	Beta-2-microglobulin Cathepsin L2 Cathepsin S HLA class I histocompatibility antigen, A alpha chain HLA class I histocompatibility antigen, B alpha chain HLA class I histocompatibility antigen, C alpha chain HLA class I histocompatibility antigen, alpha chain E HLA class I histocompatibility antigen, alpha chain F HLA class I histocompatibility antigen, alpha chain G Leucyl-cystinyl aminopeptidase Procathepsin L Putative HLA class I histocompatibility antigen, alpha chain H	O60911 P01889 P01893 P04439 P07711 P10321 P13747 P17693 P25774 P30511 P61769 Q9UIQ6	B2M CATL2 CTSL CTSL1 CTSL2 CTSS CTSU CTSV HLA-5.4 HLA-6.0 HLA-6.2 HLA-A HLA-B HLA-C HLA-E HLA-F HLA-G HLA-H HLAA HLAB HLAC HLAE HLAF HLAG HLAH LNPEP OTASE	Homo sapiens (human)
Biosynthesis of electrophilic ω-3 PUFA oxo-derivatives	Polyunsaturated fatty acid 5-lipoxygenase Prostaglandin G/H synthase 2	P09917 P35354	ALOX5 COX2 LOG5 PTGS2	Homo sapiens (human)
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants	CREB-binding protein Cullin-1 Cyclin-C Cyclin-dependent kinase 8 Delta-like protein 1 Delta-like protein 4 Disintegrin and metalloproteinase domain-containing protein 10 Disintegrin and metalloproteinase domain-containing protein 17 E3 ubiquitin-protein ligase MIB1 E3 ubiquitin-protein ligase MIB2 E3 ubiquitin-protein ligase NEURL1 E3 ubiquitin-protein ligase NEURL1B E3 ubiquitin-protein ligase RBX1 F-box-like/WD repeat-containing protein TBL1X F-box-like/WD repeat-containing protein TBL1XR1 Gamma-secretase subunit APH-1A Gamma-secretase subunit APH-1B Gamma-secretase subunit PEN-2 Hairy/enhancer-of-split related with YRPW motif protein 1 Hairy/enhancer-of-split related with YRPW motif protein 2 Hairy/enhancer-of-split related with YRPW motif-like protein Histone acetyltransferase KAT2A Histone acetyltransferase KAT2B Histone acetyltransferase p300 Histone deacetylase 11 Histone deacetylase 1 Histone deacetylase 2 Histone deacetylase 3 Histone deacetylase 4 Histone deacetylase 5 Histone deacetylase 6 Histone deacetylase 7 Histone deacetylase 8 Histone deacetylase 9 Mastermind-like domain-containing protein 1 Mastermind-like protein 1 Mastermind-like protein 2 Mastermind-like protein 3 Myc proto-oncogene protein Neurogenic locus notch homolog protein 1 Nicastrin Nuclear receptor corepressor 1 Nuclear receptor corepressor 2 Polyamine deacetylase HDAC10 Polyubiquitin-B Polyubiquitin-C Presenilin-1 Presenilin-2 Protein jagged-1 Protein jagged-2 Recombining binding protein suppressor of hairless S-phase kinase-associated protein 1 SNW domain-containing protein 1 Transcription factor HES-1 Transcription factor HES-5 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A8MQ27 O00548 O14672 O15379 O60907 O75376 O76050 P01106 P0CG47 P0CG48 P24863 P46531 P49336 P49768 P49810 P56524 P62877 P62979 P62987 P63208 P78504 P78536 Q06330 Q09472 Q13495 Q13547 Q13573 Q13616 Q14469 Q5TA89 Q86YT6 Q8IZL2 Q8WUI4 Q8WW43 Q92542 Q92585 Q92769 Q92793 Q92830 Q92831 Q969S8 Q96AX9 Q96BI3 Q96DB2 Q96JK9 Q9BY41 Q9BZK7 Q9NQ87 Q9NR61 Q9NZ42 Q9UBN7 Q9UBP5 Q9UKV0 Q9UQL6 Q9Y219 Q9Y5J3 Q9Y618	AD3 AD4 ADAM10 ADAM17 APH1A APH1B BHLHB31 BHLHB32 BHLHB33 BHLHB38 BHLHB39 BHLHE39 CBP CCNC CDK8 CG1 CHF1 CHF2 CREBBP CSVP CTG26 CUL1 CXorf6 DIP1 DLL1 DLL4 EMC19 EP300 GCN5 GCN5L2 GRL HDAC1 HDAC10 HDAC11 HDAC2 HDAC3 HDAC4 HDAC5 HDAC6 HDAC7 HDAC7A HDAC7B HDAC8 HDAC9 HDACL1 HDRP HERP HERP1 HERP2 HES1 HES5 HESR1 HEY1 HEY2 HEYL HL HRT1 HRT2 HRT3 HRY IGKJRB IGKJRB1 IRA1 JAG1 JAG2 JAGL1 KAT2A KAT2B KIAA0200 KIAA0253 KIAA0288 KIAA0600 KIAA0744 KIAA0901 KIAA1047 KIAA1323 KIAA1816 KIAA1819 KUZ MADM MAML1 MAML2 MAML3 MAMLD1 MIB1 MIB2 MITR MYC NCOR1 NCOR2 NCSTN NEURL NEURL1 NEURL1A NEURL1B NEURL3 NOTCH1 OCP2 P300 PCAF PEN2 PS1 PS2 PSEN1 PSEN2 PSENEN PSF PSFL PSNL1 PSNL2 RBPJ RBPJK RBPSUH RBX1 RNF67 RNF75 ROC1 RPD3L1 RPS27A SKD SKIIP SKIP SKP1 SKP1A SNW1 STM2 TACE TAN1 TBL1 TBL1X TBL1XR1 TBLR1 TCEB1L UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 ZZANK1 ZZANK2	Homo sapiens (human)
Vitamin D (calciferol) metabolism	1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial Cubilin E3 SUMO-protein ligase PIAS4 Legumain Low density lipoprotein receptor adapter protein 1 Low-density lipoprotein receptor-related protein 2 SUMO-conjugating enzyme UBC9 Small ubiquitin-related modifier 2 Vitamin D 25-hydroxylase Vitamin D-binding protein Vitamin D3 receptor	O15528 O60494 P02774 P11473 P61956 P63279 P98164 Q07973 Q5SW96 Q6VVX0 Q8N2W9 Q99538	ARH CUBN CYP1ALPHA CYP24 CYP24A1 CYP27B CYP27B1 CYP2R1 GC IFCR LDLRAP1 LGMN LRP2 NR1I1 PIAS4 PIASG PRSC1 SMT3B SMT3H2 SUMO2 UBC9 UBCE9 UBE2I VDR	Homo sapiens (human)
RAF-independent MAPK1/3 activation	Astrocytic phosphoprotein PEA-15 Dual specificity protein phosphatase 10 Dual specificity protein phosphatase 16 Dual specificity protein phosphatase 1 Dual specificity protein phosphatase 2 Dual specificity protein phosphatase 4 Dual specificity protein phosphatase 5 Dual specificity protein phosphatase 6 Dual specificity protein phosphatase 7 Dual specificity protein phosphatase 8 Dual specificity protein phosphatase 9 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3	P27361 P28482 P28562 Q05923 Q13115 Q13202 Q15121 Q16690 Q16828 Q16829 Q99956 Q9BY84 Q9Y6W6	C11orf81 CL100 DUSP1 DUSP10 DUSP16 DUSP2 DUSP4 DUSP5 DUSP6 DUSP7 DUSP8 DUSP9 ERK1 ERK2 KIAA1700 MAPK1 MAPK3 MKP1 MKP2 MKP3 MKP4 MKP5 MKP7 PAC1 PEA15 PRKM1 PRKM2 PRKM3 PTPN10 PYST1 PYST2 VH1 VH2 VH3 VH5	Homo sapiens (human)
ABO blood group biosynthesis	Galactoside alpha-(1,2)-fucosyltransferase 1 Galactoside alpha-(1,2)-fucosyltransferase 2 Histo-blood group ABO system transferase	P16442 P19526 Q10981	ABO FUT1 FUT2 H HSC SEC2	Homo sapiens (human)
Defective PAPSS2 causes SEMD-PA	Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2	O95340	ATPSK2 PAPSS2	Homo sapiens (human)
Autodegradation of Cdh1 by Cdh1:APC/C	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Anaphase-promoting complex subunit 10 Anaphase-promoting complex subunit 11 Anaphase-promoting complex subunit 15 Anaphase-promoting complex subunit 16 Anaphase-promoting complex subunit 1 Anaphase-promoting complex subunit 2 Anaphase-promoting complex subunit 4 Anaphase-promoting complex subunit 5 Anaphase-promoting complex subunit 7 Anaphase-promoting complex subunit CDC26 Cell division cycle protein 16 homolog Cell division cycle protein 23 homolog Cell division cycle protein 27 homolog Fizzy-related protein homolog Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-10 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Ubiquitin-conjugating enzyme E2 C Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 E1 Ubiquitin-conjugating enzyme E2 S Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00231 O00232 O00233 O00487 O00762 O14818 O43242 O75832 P0CG47 P0CG48 P17980 P20618 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P30260 P35998 P40306 P43686 P48556 P49720 P49721 P51665 P51668 P51965 P55036 P60006 P60896 P60900 P61289 P62191 P62195 P62333 P62979 P62987 Q06323 Q13042 Q13200 Q15008 Q16401 Q16763 Q8NHZ8 Q92530 Q96DE5 Q99436 Q99460 Q9H1A4 Q9NYG5 Q9UJX2 Q9UJX3 Q9UJX4 Q9UJX5 Q9UJX6 Q9UL46 Q9UM11 Q9UM13 Q9UNM6	ANAPC1 ANAPC10 ANAPC11 ANAPC12 ANAPC15 ANAPC16 ANAPC2 ANAPC3 ANAPC4 ANAPC5 ANAPC6 ANAPC7 ANAPC8 APC10 APC2 APC4 APC5 APC7 C10orf104 C11orf51 C7orf76 C9orf17 CDC16 CDC23 CDC26 CDC27 CDH1 CENP-27 D0S1430E D17S978E DSS1 E2EPF FYR FZR FZR1 HC2 HC3 HC8 HC9 HSPC IFI5111 KIAA0072 KIAA0107 KIAA1242 KIAA1406 LMP10 LMP2 LMP7 LMPX LMPY MB1 MCB1 MECL1 MIP224 MOV34L MSS1 NU PFAAP4 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB10 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSMF1 RING10 RING12 RPS27A SEM1 SFT SHFDG1 SHFM1 SUG1 SUG2 TBP1 TBP7 TRAP2 TSG24 UBA52 UBA80 UBB UBC UBC5A UBCEP1 UBCEP2 UBCH10 UBCH5 UBCH5A UBCH6 UBE2C UBE2D1 UBE2E1 UBE2S X Y Y2 Z	Homo sapiens (human)
EPHA-mediated growth cone collapse	Ephexin-1 Myosin light polypeptide 6 Myosin regulatory light chain 12B Myosin regulatory light polypeptide 9 Myosin-10 Myosin-11 Myosin-14 Myosin-9 Rho-associated protein kinase 1 Rho-associated protein kinase 2 Transforming protein RhoA Tyrosine-protein kinase Fyn Tyrosine-protein kinase Lyn Tyrosine-protein kinase Yes	O14950 O75116 P06241 P07947 P07948 P24844 P35579 P35580 P35749 P60660 P61586 Q13464 Q7Z406 Q8N5V2	ARH12 ARHA FYN JTK8 KIAA0619 KIAA0866 KIAA2034 LYN MLC2 MRLC1 MRLC2 MYH10 MYH11 MYH14 MYH9 MYL12B MYL6 MYL9 MYLC2B MYRL2 NGEF RHO12 RHOA ROCK1 ROCK2 YES YES1	Homo sapiens (human)
Axonal growth inhibition (RHOA activation)	Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 Myelin-associated glycoprotein Oligodendrocyte-myelin glycoprotein Proto-oncogene DBL Reticulon-4 Rho GDP-dissociation inhibitor 1 Transforming protein RhoA Tumor necrosis factor receptor superfamily member 16	P08138 P10911 P20916 P23515 P52565 P61586 Q96FE5 Q9NQC3	ARH12 ARHA ARHGDIA DBL GDIA1 GMA KIAA0886 LERN1 LINGO1 LRRN6A MAG MCF2 NGFR NOGO OMG OMGP RHO12 RHOA RTN4 TNFRSF16	Homo sapiens (human)
Pre-NOTCH Processing in the Endoplasmic Reticulum	GDP-fucose protein O-fucosyltransferase 1 Neurogenic locus notch homolog protein 1 Neurogenic locus notch homolog protein 2 Neurogenic locus notch homolog protein 3 Neurogenic locus notch homolog protein 4 Protein O-glucosyltransferase 1	P46531 Q04721 Q8NBL1 Q99466 Q9H488 Q9UM47	C3orf9 CLP46 FUT12 INT3 KIAA0180 KTELC1 MDSRP NOTCH1 NOTCH2 NOTCH3 NOTCH4 POFUT1 POGLUT1 TAN1	Homo sapiens (human)
linifanib-resistant FLT3 mutants	Receptor-type tyrosine-protein kinase FLT3	P36888	CD135 FLK2 FLT3 STK1	Homo sapiens (human)
Defective SLC6A3 causes Parkinsonism-dystonia infantile (PKDYS)	Sodium-dependent dopamine transporter	Q01959	DAT1 SLC6A3	Homo sapiens (human)
Hereditary fructose intolerance	Fructose-bisphosphate aldolase B	P05062	ALDB ALDOB	Homo sapiens (human)
CTNNB1 S33 mutants aren't phosphorylated	APC membrane recruitment protein 1 Adenomatous polyposis coli protein Axin-1 Casein kinase I isoform alpha Catenin beta-1 Glycogen synthase kinase-3 beta Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform	O15169 P25054 P30153 P30154 P35222 P48729 P49841 P62714 P67775 Q13362 Q14738 Q15172 Q15173 Q16537 Q5JTC6	AMER1 APC AXIN AXIN1 CSNK1A1 CTNNB CTNNB1 DP2.5 FAM123B GSK3B KIAA0044 PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E WTX	Homo sapiens (human)
Activation of NF-kappaB in B cells	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 B-cell lymphoma/leukemia 10 Caspase recruitment domain-containing protein 11 Cullin-1 F-box/WD repeat-containing protein 11 F-box/WD repeat-containing protein 1A Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Mitogen-activated protein kinase kinase kinase 7 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 NF-kappa-B essential modulator NF-kappa-B inhibitor alpha NF-kappa-B inhibitor beta NF-kappa-B inhibitor epsilon Nuclear factor NF-kappa-B p105 subunit Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Protein kinase C beta type Proto-oncogene c-Rel S-phase kinase-associated protein 1 Transcription factor p65 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A5LHX3 O00221 O00231 O00232 O00233 O00487 O14818 O14920 O15111 O43242 O43318 O75832 O95999 P05771 P0CG47 P0CG48 P17980 P19838 P20618 P25786 P25787 P25788 P25789 P25963 P28062 P28065 P28066 P28070 P28072 P28074 P35998 P40306 P43686 P48556 P49720 P49721 P51665 P55036 P60896 P60900 P61289 P62191 P62195 P62333 P62979 P62987 P63208 Q04206 Q04864 Q06323 Q13200 Q13616 Q14997 Q15008 Q15653 Q16401 Q8TAA3 Q92530 Q99436 Q99460 Q9BXL7 Q9UDY8 Q9UKB1 Q9UL46 Q9UNM6 Q9Y297 Q9Y6K9	BCL10 BTRC BTRCP BTRCP2 C7orf76 CARD11 CARMA1 CHUK CIPER CLAP CUL1 DSS1 EMC19 FBW1A FBW1B FBXW11 FBXW1A FBXW1B FIP3 HC2 HC3 HC8 HC9 HSPC IFI5111 IKBA IKBB IKBE IKBKB IKBKG IKKA IKKB KIAA0072 KIAA0077 KIAA0107 KIAA0696 LMP10 LMP2 LMP7 LMPX LMPY MAD3 MALT1 MAP3K7 MB1 MCB1 MECL1 MIP224 MLT MOV34L MSS1 NEMO NFKB1 NFKB3 NFKBI NFKBIA NFKBIB NFKBIE NU OCP2 PFAAP4 PKCB POH1 PRKCB PRKCB1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 REL RELA RING10 RING12 RPS27A SEM1 SHFDG1 SHFM1 SKP1 SKP1A SUG1 SUG2 TAK1 TBP1 TBP7 TCEB1L TCF16 TRAP2 TRIP9 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 X Y Y2 Z	Homo sapiens (human)
mRNA Capping	CDK-activating kinase assembly factor MAT1 Cyclin-H Cyclin-dependent kinase 7 DNA-directed RNA polymerase II subunit RPB11-a DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 General transcription and DNA repair factor IIH helicase subunit XPD General transcription and DNA repair factor IIH helicase/translocase subunit XPB General transcription factor IIF subunit 1 General transcription factor IIF subunit 2 General transcription factor IIH subunit 1 General transcription factor IIH subunit 2 General transcription factor IIH subunit 3 General transcription factor IIH subunit 4 General transcription factor IIH subunit 5 Nuclear cap-binding protein subunit 1 Nuclear cap-binding protein subunit 2 Transcription elongation factor SPT5 mRNA cap guanine-N7 methyltransferase mRNA-capping enzyme	O00267 O15514 O43148 O60942 P13984 P18074 P19387 P19388 P19447 P24928 P30876 P32780 P35269 P36954 P50613 P51946 P51948 P52298 P52434 P52435 P53803 P61218 P62487 P62875 Q09161 Q13888 Q13889 Q6ZYL4 Q92759	BTF2 BTF2P44 C6orf175 CAK CAK1 CAP1A CAP35 CBP20 CBP80 CCNH CDK7 CDKN7 ERCC2 ERCC3 GTF2F1 GTF2F2 GTF2H1 GTF2H2 GTF2H3 GTF2H4 GTF2H5 KIAA0398 MAT1 MNAT1 MO15 NCBP NCBP1 NCBP2 POLR2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J1 POLR2K POLR2L POLRF RAP30 RAP74 RNF66 RNGTT RNMT RPB7 SPT5 SPT5H STK1 SUPT5H TTDA XPB XPBC XPD XPDC	Homo sapiens (human)
Metabolism of Angiotensinogen to Angiotensins	Aminopeptidase N Angiotensin-converting enzyme 2 Angiotensin-converting enzyme Angiotensinogen Carboxypeptidase B2 Carboxypeptidase B Cathepsin D Cathepsin G Cathepsin Z Chymase Glutamyl aminopeptidase Granzyme H Liver carboxylesterase 1 Mast cell carboxypeptidase A Neprilysin Renin receptor Renin	O75787 P00797 P01019 P07339 P08311 P08473 P12821 P15086 P15088 P15144 P20718 P23141 P23946 Q07075 Q96IY4 Q9BYF1 Q9UBR2	ACE ACE2 AGT ANPEP APN ATP6AP2 ATP6IP2 CAPER CD13 CES1 CES2 CGL2 CMA1 CPA3 CPB CPB1 CPB2 CPSD CTSD CTSG CTSGL2 CTSZ CYH CYM DCP DCP1 ELDF10 ENPEP EPN GZMH MME PCPB PEPN REN SERPINA8 SES1	Homo sapiens (human)
Defective SLC26A4 causes Pendred syndrome (PDS)	Pendrin	O43511	PDS SLC26A4	Homo sapiens (human)
Interleukin-2 signaling	Cytokine receptor common subunit gamma Interleukin-2 receptor subunit alpha Interleukin-2 receptor subunit beta Interleukin-2 Protein-tyrosine kinase 2-beta SHC-transforming protein 1 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Tyrosine-protein kinase JAK1 Tyrosine-protein kinase JAK3 Tyrosine-protein kinase Lck Tyrosine-protein kinase SYK	P01589 P06239 P14784 P23458 P29353 P31785 P42229 P43405 P51692 P52333 P60568 Q14289	FAK2 IL15RB IL2 IL2RA IL2RB IL2RG JAK1 JAK1A JAK1B JAK3 LCK PTK2B PYK2 RAFTK SHC SHC1 SHCA STAT5 STAT5A STAT5B SYK	Homo sapiens (human)
Defective SLC6A18 may confer susceptibility to iminoglycinuria and/or hyperglycinuria	Inactive sodium-dependent neutral amino acid transporter B(0)AT3	Q96N87	B0AT3 SLC6A18 XTRP2	Homo sapiens (human)
Translation of respiratory syncytial virus mRNAs	Fusion glycoprotein F0 Matrix protein Non-structural protein 1 Non-structural protein 2 Nucleoprotein Phosphoprotein Protein M2-1 Protein M2-2 RNA-directed RNA polymerase L	P03418 P03420 P03421 P04543 P04545 P0DOE7 P0DOE9 P28887 P88812	1B 1C F L M M2-1 M2-2 N NS1 NS2 P	Homo sapiens (human)
Oleoyl-phe metabolism	N-fatty-acyl-amino acid synthase/hydrolase PM20D1	Q6GTS8	PM20D1	Homo sapiens (human)
Response of EIF2AK4 (GCN2) to amino acid deficiency	Asparagine synthetase [glutamine-hydrolyzing] CCAAT/enhancer-binding protein beta CCAAT/enhancer-binding protein gamma Cyclic AMP-dependent transcription factor ATF-2 Cyclic AMP-dependent transcription factor ATF-3 Cyclic AMP-dependent transcription factor ATF-4 DNA damage-inducible transcript 3 protein Eukaryotic translation initiation factor 2 subunit 1 Eukaryotic translation initiation factor 2 subunit 2 Eukaryotic translation initiation factor 2 subunit 3 Large ribosomal subunit protein P1 Large ribosomal subunit protein P2 Large ribosomal subunit protein eL13 Large ribosomal subunit protein eL14 Large ribosomal subunit protein eL15 Large ribosomal subunit protein eL18 Large ribosomal subunit protein eL19 Large ribosomal subunit protein eL20 Large ribosomal subunit protein eL21 Large ribosomal subunit protein eL22 Large ribosomal subunit protein eL24 Large ribosomal subunit protein eL27 Large ribosomal subunit protein eL28 Large ribosomal subunit protein eL29 Large ribosomal subunit protein eL30 Large ribosomal subunit protein eL31 Large ribosomal subunit protein eL32 Large ribosomal subunit protein eL33 Large ribosomal subunit protein eL34 Large ribosomal subunit protein eL36 Large ribosomal subunit protein eL37 Large ribosomal subunit protein eL38 Large ribosomal subunit protein eL39 Large ribosomal subunit protein eL42 Large ribosomal subunit protein eL43 Large ribosomal subunit protein eL6 Large ribosomal subunit protein eL8 Large ribosomal subunit protein uL10 Large ribosomal subunit protein uL11 Large ribosomal subunit protein uL13 Large ribosomal subunit protein uL14 Large ribosomal subunit protein uL15 Large ribosomal subunit protein uL16 Large ribosomal subunit protein uL18 Large ribosomal subunit protein uL1 Large ribosomal subunit protein uL22 Large ribosomal subunit protein uL23 Large ribosomal subunit protein uL24 Large ribosomal subunit protein uL29 Large ribosomal subunit protein uL2 Large ribosomal subunit protein uL30 Large ribosomal subunit protein uL3 Large ribosomal subunit protein uL4 Large ribosomal subunit protein uL5 Large ribosomal subunit protein uL6 Protein IMPACT Ribosomal protein eL22-like Ribosomal protein eL39-like 2 Ribosomal protein eL42-like Ribosomal protein eS27-like Ribosomal protein uL16-like Ribosomal protein uL24-like Ribosomal protein uL3-like Small ribosomal subunit protein eS10 Small ribosomal subunit protein eS12 Small ribosomal subunit protein eS17 Small ribosomal subunit protein eS19 Small ribosomal subunit protein eS1 Small ribosomal subunit protein eS21 Small ribosomal subunit protein eS24 Small ribosomal subunit protein eS25 Small ribosomal subunit protein eS26 Small ribosomal subunit protein eS27 Small ribosomal subunit protein eS28 Small ribosomal subunit protein eS32 Small ribosomal subunit protein eS4, X isoform Small ribosomal subunit protein eS4, Y isoform 1 Small ribosomal subunit protein eS4, Y isoform 2 Small ribosomal subunit protein eS6 Small ribosomal subunit protein eS7 Small ribosomal subunit protein eS8 Small ribosomal subunit protein uS10 Small ribosomal subunit protein uS11 Small ribosomal subunit protein uS12 Small ribosomal subunit protein uS13 Small ribosomal subunit protein uS14 Small ribosomal subunit protein uS15 Small ribosomal subunit protein uS17 Small ribosomal subunit protein uS19 Small ribosomal subunit protein uS2 Small ribosomal subunit protein uS3 Small ribosomal subunit protein uS4 Small ribosomal subunit protein uS5 Small ribosomal subunit protein uS7 Small ribosomal subunit protein uS8 Small ribosomal subunit protein uS9 Stalled ribosome sensor GCN1 Tribbles homolog 3 Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein eIF-2-alpha kinase GCN2	P05198 P05386 P05387 P05388 P08243 P08708 P08865 P15336 P15880 P17676 P18077 P18124 P18621 P18847 P18848 P20042 P22090 P23396 P25398 P26373 P27635 P30050 P32969 P35268 P35638 P36578 P39019 P39023 P40429 P41091 P42677 P42766 P46776 P46777 P46778 P46779 P46781 P46782 P46783 P47914 P49207 P50914 P53567 P60866 P61247 P61254 P61313 P61353 P61513 P61927 P62081 P62241 P62244 P62249 P62263 P62266 P62269 P62273 P62277 P62280 P62424 P62701 P62750 P62753 P62829 P62841 P62847 P62851 P62854 P62857 P62861 P62888 P62891 P62899 P62906 P62910 P62913 P62917 P62945 P62979 P62987 P63173 P63220 P83731 P83881 P84098 Q02543 Q02878 Q07020 Q6P5R6 Q71UM5 Q8TD47 Q92616 Q92901 Q969Q0 Q96EH5 Q96L21 Q96RU7 Q9P2K8 Q9P2X3 Q9UNX3 Q9Y3U8	ASNS ATF2 ATF3 ATF4 BBC1 C20orf97 CCG2 CEBPB CEBPG CHOP CHOP10 CREB2 CREBP1 D11S2243E D6S218E DDIT3 DXS648E EC45 EIF2A EIF2AK4 EIF2B EIF2G EIF2S1 EIF2S2 EIF2S3 FAU FTE1 GADD153 GCN1 GCN1L1 GCN2 IMPACT KIAA0219 KIAA1338 LAMBR LAMR1 MFTL MPS1 NEDD6 NIPK QM RIG RPL1 RPL10 RPL10A RPL10L RPL11 RPL12 RPL13 RPL13A RPL14 RPL15 RPL17 RPL18 RPL18A RPL19 RPL21 RPL22 RPL22L1 RPL23 RPL23A RPL24 RPL26 RPL26L1 RPL26P1 RPL27 RPL27A RPL28 RPL29 RPL3 RPL30 RPL31 RPL32 RPL34 RPL35 RPL35A RPL36 RPL36A RPL36AL RPL37 RPL37A RPL38 RPL39 RPL39L RPL39L1 RPL3L RPL4 RPL41 RPL44 RPL5 RPL6 RPL7 RPL7A RPL8 RPL9 RPL9P7 RPL9P8 RPL9P9 RPLP0 RPLP1 RPLP2 RPP2 RPS10 RPS11 RPS12 RPS13 RPS14 RPS15 RPS15A RPS16 RPS17 RPS17L RPS18 RPS19 RPS2 RPS20 RPS21 RPS23 RPS24 RPS25 RPS26 RPS27 RPS27A RPS27L RPS28 RPS29 RPS3 RPS3A RPS4 RPS4X RPS4Y RPS4Y1 RPS4Y2 RPS4Y2P RPS5 RPS6 RPS7 RPS8 RPS9 RPSA RRP1 SCAR SKIP3 SURF-3 SURF3 TCF5 TRB3 TRIB3 TS11 TXREB TXREB1 UBA52 UBA80 UBCEP1 UBCEP2	Homo sapiens (human)
Interleukin-37 signaling	Caspase-1 Interleukin-18 receptor 1 Interleukin-18-binding protein Interleukin-37 Mothers against decapentaplegic homolog 3 Serine/threonine-protein kinase TBK1 Signal transducer and activator of transcription 3 Single Ig IL-1-related receptor Tyrosine-protein phosphatase non-receptor type 11 Tyrosine-protein phosphatase non-receptor type 12 Tyrosine-protein phosphatase non-receptor type 13 Tyrosine-protein phosphatase non-receptor type 14 Tyrosine-protein phosphatase non-receptor type 18 Tyrosine-protein phosphatase non-receptor type 20 Tyrosine-protein phosphatase non-receptor type 23 Tyrosine-protein phosphatase non-receptor type 2 Tyrosine-protein phosphatase non-receptor type 4 Tyrosine-protein phosphatase non-receptor type 5 Tyrosine-protein phosphatase non-receptor type 6 Tyrosine-protein phosphatase non-receptor type 7 Tyrosine-protein phosphatase non-receptor type 9	O95998 P17706 P29074 P29350 P29466 P35236 P40763 P43378 P54829 P84022 Q05209 Q06124 Q12923 Q13478 Q15678 Q4JDL3 Q6IA17 Q99952 Q9H3S7 Q9NZH6 Q9UHD2	APRF BDP1 CASP1 FIL1Z HCP IL18BP IL18R1 IL1BC IL1BCE IL1F7 IL1H4 IL1RP1 IL1RRP IL37 KIAA1471 MADH3 NAK PEZ PNP1 PTP1C PTP1E PTP2C PTPD2 PTPL1 PTPN11 PTPN12 PTPN13 PTPN14 PTPN18 PTPN2 PTPN20 PTPN20A PTPN20B PTPN23 PTPN4 PTPN5 PTPN6 PTPN7 PTPN9 PTPT SHPTP2 SIGIRR SMAD3 STAT3 TBK1	Homo sapiens (human)

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