GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **1476 - 1500** of **2090** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism ▼
Translation of Accessory Proteins	ORF6 protein ORF7a protein ORF8 protein ORF9b protein	P0DTC6 P0DTC7 P0DTC8 P0DTD2	6 7a 8 9b	Homo sapiens (human)
Dual incision in TC-NER	CDK-activating kinase assembly factor MAT1 Cullin-4A Cullin-4B Cyclin-H Cyclin-dependent kinase 7 DNA damage-binding protein 1 DNA excision repair protein ERCC-1 DNA excision repair protein ERCC-5 DNA excision repair protein ERCC-6 DNA excision repair protein ERCC-8 DNA polymerase delta catalytic subunit DNA polymerase delta subunit 2 DNA polymerase delta subunit 3 DNA polymerase delta subunit 4 DNA polymerase epsilon catalytic subunit A DNA polymerase epsilon subunit 2 DNA polymerase epsilon subunit 3 DNA polymerase epsilon subunit 4 DNA polymerase kappa DNA repair endonuclease XPF DNA repair protein complementing XP-A cells DNA-directed RNA polymerase II subunit RPB11-a DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 E3 ubiquitin-protein ligase RBX1 General transcription and DNA repair factor IIH helicase subunit XPD General transcription and DNA repair factor IIH helicase/translocase subunit XPB General transcription factor IIH subunit 1 General transcription factor IIH subunit 2 General transcription factor IIH subunit 3 General transcription factor IIH subunit 4 General transcription factor IIH subunit 5 Peptidyl-prolyl cis-trans isomerase E Polyubiquitin-B Polyubiquitin-C Pre-mRNA-processing factor 19 Pre-mRNA-splicing factor ISY1 homolog Pre-mRNA-splicing factor SYF1 Proliferating cell nuclear antigen RNA helicase aquarius Replication factor C subunit 1 Replication factor C subunit 2 Replication factor C subunit 3 Replication factor C subunit 4 Replication factor C subunit 5 Replication protein A 14 kDa subunit Replication protein A 32 kDa subunit Replication protein A 70 kDa DNA-binding subunit Transcription elongation factor A protein 1 UV-stimulated scaffold protein A Ubiquitin carboxyl-terminal hydrolase 7 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Zinc finger protein 830	O15514 O60306 P07992 P0CG47 P0CG48 P12004 P15927 P18074 P19387 P19388 P19447 P23025 P23193 P24928 P27694 P28340 P28715 P30876 P32780 P35244 P35249 P35250 P35251 P36954 P40937 P40938 P49005 P50613 P51946 P51948 P52434 P52435 P53803 P56282 P61218 P62487 P62875 P62877 P62979 P62987 Q03468 Q07864 Q13216 Q13619 Q13620 Q13888 Q13889 Q15054 Q16531 Q2YD98 Q6ZYL4 Q92759 Q92889 Q93009 Q96NB3 Q9HCS7 Q9HCU8 Q9NR33 Q9NRF9 Q9UBT6 Q9ULR0 Q9UMS4 Q9UNP9	AQR BTF2 BTF2P44 C6orf175 CAK CAK1 CAP35 CCDC16 CCNH CDK7 CDKN7 CHRAC17 CKN1 CSA CSB CUL4A CUL4B CYP33 DDB1 DINB1 DPE2 ERCC1 ERCC11 ERCC2 ERCC3 ERCC4 ERCC5 ERCC6 ERCC8 ERCM2 GTF2H1 GTF2H2 GTF2H3 GTF2H4 GTF2H5 GTF2S HAUSP HCNP ISY1 KIAA0039 KIAA0560 KIAA0695 KIAA1160 KIAA1177 KIAA1530 MAT1 MNAT1 MO15 NMP200 PCNA POLD POLD1 POLD2 POLD3 POLD4 POLDS POLE POLE1 POLE2 POLE3 POLE4 POLK POLR2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J1 POLR2K POLR2L POLRF PPIE PRP19 PRPF19 RBX1 REPA1 REPA2 REPA3 RFC1 RFC140 RFC2 RFC3 RFC4 RFC5 RNF66 RNF75 ROC1 RPA1 RPA14 RPA2 RPA3 RPA32 RPA34 RPA70 RPB7 RPS27A SNEV STK1 SYF1 TCEA1 TFIIS TTDA UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 USP7 UVSSA XAB2 XAP1 XPA XPAC XPB XPBC XPD XPDC XPF XPG XPGC ZNF830	Homo sapiens (human)
Impaired BRCA2 binding to SEM1 (DSS1)	26S proteasome complex subunit SEM1 Breast cancer type 2 susceptibility protein	P51587 P60896	BRCA2 C7orf76 DSS1 FACD FANCD1 SEM1 SHFDG1 SHFM1	Homo sapiens (human)
Dopamine receptors	D(1A) dopamine receptor D(1B) dopamine receptor D(2) dopamine receptor D(3) dopamine receptor D(4) dopamine receptor	P14416 P21728 P21917 P21918 P35462	DRD1 DRD1B DRD1L2 DRD2 DRD3 DRD4 DRD5	Homo sapiens (human)
Apoptotic cleavage of cell adhesion proteins	Cadherin-1 Caspase-3 Catenin beta-1 Desmoglein-1 Desmoglein-2 Desmoglein-3 Desmoplakin Occludin Plakophilin-1 Tight junction protein ZO-1 Tight junction protein ZO-2	P12830 P15924 P32926 P35222 P42574 Q02413 Q07157 Q13835 Q14126 Q16625 Q9UDY2	CASP3 CDH1 CDHE CDHF4 CDHF5 CDHF6 CPP32 CTNNB CTNNB1 DSG1 DSG2 DSG3 DSP OCLN PKP1 TJP1 TJP2 UVO X104 ZO1 ZO2	Homo sapiens (human)
EPHB-mediated forward signaling	Actin nucleation-promoting factor WASL Actin, cytoplasmic 1 Actin, cytoplasmic 2 Actin-related protein 2/3 complex subunit 1A Actin-related protein 2/3 complex subunit 1B Actin-related protein 2/3 complex subunit 2 Actin-related protein 2/3 complex subunit 3 Actin-related protein 2/3 complex subunit 4 Actin-related protein 2/3 complex subunit 5 Actin-related protein 2 Actin-related protein 3 Cell division control protein 42 homolog Cofilin-1 Focal adhesion kinase 1 GTPase HRas Glutamate receptor ionotropic, NMDA 1 Glutamate receptor ionotropic, NMDA 2B Intersectin-1 Kalirin LIM domain kinase 1 LIM domain kinase 2 Ras GTPase-activating protein 1 Ras-related C3 botulinum toxin substrate 1 Rho guanine nucleotide exchange factor 28 Rho guanine nucleotide exchange factor TIAM1 Rho-associated protein kinase 1 Rho-associated protein kinase 2 Serine/threonine-protein kinase PAK 1 Syndecan-2 Transforming protein RhoA Tyrosine-protein kinase Fyn Tyrosine-protein kinase Lyn Tyrosine-protein kinase Yes	O00401 O15143 O15144 O15145 O15511 O60229 O75116 P01112 P06241 P07947 P07948 P20936 P23528 P34741 P53667 P53671 P59998 P60709 P60953 P61158 P61160 P61586 P63000 P63261 Q05397 Q05586 Q13009 Q13153 Q13224 Q13464 Q15811 Q8N1W1 Q92747	ACTB ACTG ACTG1 ACTR2 ACTR3 ARC16 ARC20 ARC21 ARC34 ARC41 ARH12 ARHA ARHGEF28 ARP2 ARP3 ARPC1A ARPC1B ARPC2 ARPC3 ARPC4 ARPC5 CDC42 CFL CFL1 DUET DUO FAK FAK1 FYN GAP GRIN1 GRIN2B HAPIP HRAS HRAS1 HSPG1 ITSN ITSN1 JTK8 KALRN KIAA0619 KIAA1998 LIMK LIMK1 LIMK2 LYN NMDAR1 NMDAR2B PAK1 PTK2 RAC1 RASA RASA1 RGNEF RHO12 RHOA ROCK1 ROCK2 SDC2 SH3D1A SOP2L TC25 TIAM1 TRAD WASL YES YES1	Homo sapiens (human)
Phosphate bond hydrolysis by NUDT proteins	ADP-sugar pyrophosphatase Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase Nucleotide triphosphate diphosphatase NUDT15 U8 snoRNA-decapping enzyme	Q3LIE5 Q96DE0 Q9NV35 Q9UKK9	ADPRM C17orf48 MTH2 NUDIX5 NUDT15 NUDT16 NUDT5	Homo sapiens (human)
Phosphate bond hydrolysis by NTPDase proteins	Ectonucleoside triphosphate diphosphohydrolase 1 Ectonucleoside triphosphate diphosphohydrolase 2 Ectonucleoside triphosphate diphosphohydrolase 3 Ectonucleoside triphosphate diphosphohydrolase 4 Ectonucleoside triphosphate diphosphohydrolase 6 Ectonucleoside triphosphate diphosphohydrolase 7 Ectonucleoside triphosphate diphosphohydrolase 8 Nucleoside diphosphate phosphatase ENTPD5	O75354 O75355 O75356 P49961 Q5MY95 Q9NQZ7 Q9Y227 Q9Y5L3	CD39 CD39L1 CD39L2 CD39L3 CD39L4 ENTPD1 ENTPD2 ENTPD3 ENTPD4 ENTPD5 ENTPD6 ENTPD7 ENTPD8 IL6ST2 KIAA0392 LALP1 LALP70 LYSAL1 PCPH	Homo sapiens (human)
COPII-mediated vesicle transport	Alpha-1-antitrypsin Alpha-soluble NSF attachment protein Amphiregulin BET1 homolog Beta-soluble NSF attachment protein CD59 glycoprotein Casein kinase I isoform delta Cathepsin Z Coagulation factor V Coagulation factor VIII Collagen alpha-1(VII) chain Dipeptidyl peptidase 1 Folate receptor alpha Gamma-soluble NSF attachment protein General vesicular transport factor p115 Glutamate receptor 1 Golgi SNAP receptor complex member 2 Golgi reassembly-stacking protein 1 Golgin subfamily A member 2 Guanine nucleotide-exchange factor SEC12 Multiple coagulation factor deficiency protein 2 Protein ERGIC-53-like Protein ERGIC-53 Protein SEC13 homolog Protein TFG Protein cornichon homolog 1 Protein cornichon homolog 2 Protein cornichon homolog 3 Protein transport protein Sec16A Protein transport protein Sec16B Protein transport protein Sec23A Protein transport protein Sec24A Protein transport protein Sec24B Protein transport protein Sec24C Protein transport protein Sec24D Protein transport protein Sec31A Protransforming growth factor alpha Ras-related protein Rab-1A Ras-related protein Rab-1B SEC23-interacting protein Sec1 family domain-containing protein 1 Serine/threonine-protein phosphatase 6 catalytic subunit Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A Serine/threonine-protein phosphatase 6 regulatory subunit 1 Serine/threonine-protein phosphatase 6 regulatory subunit 3 Small COPII coat GTPase SAR1B Synaptobrevin homolog YKT6 Syntaxin-17 Syntaxin-5 TBC1 domain family member 20 Trafficking protein particle complex subunit 10 Trafficking protein particle complex subunit 1 Trafficking protein particle complex subunit 2-like protein Trafficking protein particle complex subunit 2 Trafficking protein particle complex subunit 3 Trafficking protein particle complex subunit 4 Trafficking protein particle complex subunit 5 Trafficking protein particle complex subunit 6A Trafficking protein particle complex subunit 6B Trafficking protein particle complex subunit 9 Transmembrane emp24 domain-containing protein 10 Transmembrane emp24 domain-containing protein 2 VIP36-like protein Vesicle-fusing ATPase Vesicle-trafficking protein SEC22a Vesicle-trafficking protein SEC22b Vesicle-trafficking protein SEC22c Vesicular integral-membrane protein VIP36	O00743 O14653 O15027 O15084 O15155 O15498 O43617 O60763 O75396 O75865 O94855 O94979 O95406 O95486 O95487 P00451 P01009 P01135 P0DI81 P12259 P13987 P15328 P15514 P42261 P46459 P48553 P48730 P49257 P49755 P53634 P53992 P54920 P55735 P56962 P62820 Q02388 Q08379 Q12907 Q13190 Q15363 Q15436 Q5H9R7 Q6PI25 Q86SZ2 Q8IUR0 Q8NI22 Q8TBE1 Q8WVM8 Q92734 Q96BZ9 Q96IW7 Q96JE7 Q96Q05 Q99747 Q9BQQ3 Q9BRL7 Q9H0U4 Q9H0V9 Q9H115 Q9HAT1 Q9HCU5 Q9UBR2 Q9UL33 Q9UPN7 Q9Y296 Q9Y5R8 Q9Y6B6 Q9Y6Y8	AAT ANKRD28 AREG AREGB BET1 BET3 BET5 C11orf23 C14orf163 C20orf140 C5orf8 CD59 CNIH CNIH1 CNIH2 CNIH3 CNIL COL7A1 CPPI CSNK1D CTSC CTSZ D3S1231E EHOC1 ERGIC53 ERGL F5 F5F8D F8 F8C FOLR FOLR1 GLUA1 GLUH1 GLUR1 GOLGA2 GOLPH5 GORASP1 GOSR2 GRASP65 GRIA1 GS27 HCKID KIAA0079 KIAA0310 KIAA0379 KIAA0755 KIAA0905 KIAA0917 KIAA1115 KIAA1558 KIAA1882 KIAA1928 LMAN1 LMAN1L LMAN2 LMAN2L LZTR2 MCFD2 MIC11 MIN1 MIN2 MIN3 MSK21 MUM2 NAPA NAPB NAPG NIBP NSF PI PP6R1 PP6R3 PPP6 PPP6C PPP6R1 PPP6R3 PREB RAB1 RAB1A RAB1B RGPR RNP24 SAPL SAPS1 SAPS3 SAR1B SARA2 SARB SBDN SCFD1 SDGF SDNSF SEC12 SEC13 SEC13A SEC13L1 SEC13R SEC16 SEC16A SEC16B SEC16L SEC16S SEC22A SEC22B SEC22C SEC22L1 SEC22L2 SEC22L3 SEC23A SEC23IP SEC24A SEC24B SEC24C SEC24D SEC31A SEC31L1 SEDL SERPINA1 SNAPA SNAPB SNAPG STX17 STX5 STX5A STXBP1L2 TBC1D20 TFG TGFA TMED10 TMED2 TMEM1 TMP21 TRAPPC1 TRAPPC10 TRAPPC2 TRAPPC2L TRAPPC3 TRAPPC4 TRAPPC5 TRAPPC6A TRAPPC6B TRAPPC9 USO1 VDP VIPL YKT6	Homo sapiens (human)
Lipophagy	5'-AMP-activated protein kinase catalytic subunit alpha-2 5'-AMP-activated protein kinase subunit beta-1 5'-AMP-activated protein kinase subunit beta-2 5'-AMP-activated protein kinase subunit gamma-1 5'-AMP-activated protein kinase subunit gamma-2 5'-AMP-activated protein kinase subunit gamma-3 Heat shock cognate 71 kDa protein Perilipin-2 Perilipin-3	O43741 O60664 P11142 P54619 P54646 Q99541 Q9UGI9 Q9UGJ0 Q9Y478	ADFP AMPK AMPK2 AMPKG3 HSC70 HSP73 HSPA10 HSPA8 M6PRBP1 PLIN2 PLIN3 PRKAA2 PRKAB1 PRKAB2 PRKAG1 PRKAG2 PRKAG3 TIP47	Homo sapiens (human)
SARS-CoV-1-host interactions	Heterogeneous nuclear ribonucleoprotein A1 Nucleophosmin Nucleoprotein	P06748 P09651 P59595	HNRNPA1 HNRPA1 N NPM NPM1	Homo sapiens (human)
tandutinib-resistant FLT3 mutants	Receptor-type tyrosine-protein kinase FLT3	P36888	CD135 FLK2 FLT3 STK1	Homo sapiens (human)
CREB3 factors activate genes	CREB3 regulatory factor Cyclic AMP-responsive element-binding protein 3-like protein 1 Cyclic AMP-responsive element-binding protein 3-like protein 2 Cyclic AMP-responsive element-binding protein 3-like protein 3 Cyclic AMP-responsive element-binding protein 3-like protein 4 Cyclic AMP-responsive element-binding protein 3 Dendritic cell-specific transmembrane protein Membrane-bound transcription factor site-1 protease Membrane-bound transcription factor site-2 protease	O43462 O43889 Q14703 Q68CJ9 Q70SY1 Q8IUR6 Q8TEY5 Q96BA8 Q9H295	AIBZIP BBF2H7 C5orf41 CREB3 CREB3L1 CREB3L2 CREB3L3 CREB3L4 CREB4 CREBH CREBRF DCSTAMP JAL KIAA0091 LZIP MBTPS1 MBTPS2 OASIS S1P S2P SKI1 TM7SF4	Homo sapiens (human)
Late endosomal microautophagy	ADP-ribosylation factor-like protein 13B Centrin-1 Charged multivesicular body protein 2a Charged multivesicular body protein 2b Charged multivesicular body protein 3 Charged multivesicular body protein 4a Charged multivesicular body protein 4b Charged multivesicular body protein 4c Charged multivesicular body protein 6 Charged multivesicular body protein 7 Cystic fibrosis transmembrane conductance regulator Heat shock cognate 71 kDa protein Hemoglobin subunit beta Histone deacetylase 6 Intraflagellar transport protein 88 homolog Multivesicular body subunit 12A Multivesicular body subunit 12B Parkinson disease protein 7 Pericentrin Perilipin-2 Perilipin-3 Polyubiquitin-B Polyubiquitin-C Ribonuclease pancreatic Tumor susceptibility gene 101 protein Ubiquitin-associated protein 1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Vacuolar protein sorting-associated protein 28 homolog Vacuolar protein sorting-associated protein 37A Vacuolar protein sorting-associated protein 37B Vacuolar protein sorting-associated protein 37C Vacuolar protein sorting-associated protein 37D	A5D8V6 O43633 O60664 O95613 P07998 P0CG47 P0CG48 P11142 P13569 P62979 P62987 P68871 Q12798 Q13099 Q3SXY8 Q86XT2 Q8NEZ2 Q8WUX9 Q96CF2 Q96EY5 Q96FZ7 Q99497 Q99541 Q99816 Q9BY43 Q9H444 Q9H7P6 Q9H9H4 Q9NZ09 Q9UBN7 Q9UK41 Q9UQN3 Q9Y3E7	ABCC7 ADFP ARL13B ARL2L1 BC2 C14orf123 C20orf178 C9orf28 CEN1 CETN CETN1 CFBP CFTR CGI149 CHMP2 CHMP2A CHMP2B CHMP3 CHMP4A CHMP4B CHMP4C CHMP6 CHMP7 FAM125A FAM125B HBB HCRP1 HDAC6 HSC70 HSP73 HSPA10 HSPA8 IFT88 KIAA0402 KIAA0901 M6PRBP1 MVB12A MVB12B NEDF PARK7 PCNT PCNT2 PLIN2 PLIN3 PML39 RIB1 RNASE1 RNS1 RPS27A SHAX1 SHAX2 SHAX3 TG737 TIP47 TSG101 TTC10 UBA52 UBA80 UBAP1 UBB UBC UBCEP1 UBCEP2 VPS20 VPS24 VPS28 VPS37A VPS37B VPS37C VPS37D WBSCR24	Homo sapiens (human)
Defective ABCC8 can cause hypo- and hyper-glycemias	ATP-binding cassette sub-family C member 8 ATP-sensitive inward rectifier potassium channel 11	Q09428 Q14654	ABCC8 HRINS KCNJ11 SUR SUR1	Homo sapiens (human)
Defective SLC7A7 causes lysinuric protein intolerance (LPI)	Amino acid transporter heavy chain SLC3A2 Y+L amino acid transporter 1	P08195 Q9UM01	MDU1 SLC3A2 SLC7A7	Homo sapiens (human)
SMAC, XIAP-regulated apoptotic response	Caspase-3 Caspase-7 Diablo IAP-binding mitochondrial protein E3 ubiquitin-protein ligase XIAP	P42574 P55210 P98170 Q9NR28	API3 BIRC4 CASP3 CASP7 CPP32 DIABLO IAP3 MCH3 SMAC XIAP	Homo sapiens (human)
TP53 Regulates Metabolic Genes	14-3-3 protein beta/alpha 14-3-3 protein epsilon 14-3-3 protein eta 14-3-3 protein gamma 14-3-3 protein sigma 14-3-3 protein theta 14-3-3 protein zeta/delta 5'-AMP-activated protein kinase catalytic subunit alpha-1 5'-AMP-activated protein kinase catalytic subunit alpha-2 5'-AMP-activated protein kinase subunit beta-1 5'-AMP-activated protein kinase subunit beta-2 5'-AMP-activated protein kinase subunit gamma-1 5'-AMP-activated protein kinase subunit gamma-2 5'-AMP-activated protein kinase subunit gamma-3 Cellular tumor antigen p53 Cytochrome c oxidase assembly protein COX11, mitochondrial Cytochrome c oxidase assembly protein COX14 Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial Cytochrome c oxidase assembly protein COX18, mitochondrial Cytochrome c oxidase assembly protein COX19 Cytochrome c oxidase assembly protein COX20, mitochondrial Cytochrome c oxidase subunit 1 Cytochrome c oxidase subunit 2 Cytochrome c oxidase subunit 3 Cytochrome c oxidase subunit 4 isoform 1, mitochondrial Cytochrome c oxidase subunit 5A, mitochondrial Cytochrome c oxidase subunit 5B, mitochondrial Cytochrome c oxidase subunit 6A1, mitochondrial Cytochrome c oxidase subunit 6B1 Cytochrome c oxidase subunit 6C Cytochrome c oxidase subunit 7A-related protein, mitochondrial Cytochrome c oxidase subunit 7B, mitochondrial Cytochrome c oxidase subunit 7C, mitochondrial Cytochrome c oxidase subunit 8A, mitochondrial Cytochrome c oxidase subunit NDUFA4 Cytochrome c DNA damage-inducible transcript 4 protein Fructose-2,6-bisphosphatase TIGAR GTP-binding protein Rheb Glucose-6-phosphate 1-dehydrogenase Glucose-6-phosphate isomerase Glutaminase kidney isoform, mitochondrial Glutaminase liver isoform, mitochondrial Glutathione peroxidase 2 Hamartin Helicase MOV-10 Leucine-rich PPR motif-containing protein, mitochondrial Neutral amino acid transporter 9 Peroxiredoxin-1 Peroxiredoxin-2 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN Protein SCO1 homolog, mitochondrial Protein SCO2 homolog, mitochondrial Protein argonaute-1 Protein argonaute-2 Protein argonaute-3 Protein argonaute-4 RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Ragulator complex protein LAMTOR1 Ragulator complex protein LAMTOR2 Ragulator complex protein LAMTOR3 Ragulator complex protein LAMTOR4 Ragulator complex protein LAMTOR5 Ras-related GTP-binding protein A Ras-related GTP-binding protein B Ras-related GTP-binding protein C Ras-related GTP-binding protein D Regulatory-associated protein of mTOR Ribonucleoside-diphosphate reductase subunit M2 B Serine/threonine-protein kinase mTOR Sestrin-2 Sestrin-3 Surfeit locus protein 1 Target of rapamycin complex subunit LST8 Thioredoxin reductase 1, cytoplasmic Thioredoxin Translational activator of cytochrome c oxidase 1 Trinucleotide repeat-containing gene 6A protein Trinucleotide repeat-containing gene 6B protein Trinucleotide repeat-containing gene 6C protein Tuberin Tumor protein 63	O00483 O14548 O43504 O43741 O43819 O75880 O94925 P00395 P00403 P00414 P04637 P06744 P09669 P10176 P10599 P10606 P11413 P12074 P13073 P14854 P15954 P18283 P20674 P24311 P27348 P31749 P31751 P31946 P31947 P32119 P42345 P42704 P49815 P54619 P54646 P58004 P58005 P60484 P61981 P62258 P63104 P99999 Q04917 Q06830 Q0VGL1 Q13131 Q15382 Q15526 Q16881 Q49B96 Q5RI15 Q5VZM2 Q6IAA8 Q7L523 Q7LG56 Q8N122 Q8N8Q8 Q8NBW4 Q8NDV7 Q92574 Q96I36 Q9BSH4 Q9BVC4 Q9H3D4 Q9H9G7 Q9HB90 Q9HCE1 Q9HCJ0 Q9HCK5 Q9NQ88 Q9NQL2 Q9NX09 Q9P0S2 Q9UGI9 Q9UGJ0 Q9UHA4 Q9UI32 Q9UKV8 Q9UL18 Q9UPQ9 Q9Y243 Q9Y2Q5 Q9Y478 Q9Y6N1	AGO1 AGO2 AGO3 AGO4 AKT1 AKT2 AKT3 AMPK AMPK1 AMPK2 AMPKG3 C11orf59 C12orf5 C12orf62 C14orf112 C7orf59 CAGH26 CCDC44 COI COII COIII COX11 COX14 COX16 COX18 COX19 COX2 COX20 COX4 COX4I1 COX5A COX5B COX6A1 COX6AL COX6B COX6B1 COX6C COX7A2L COX7AR COX7B COX7C COX7RP COX8 COX8A COX8L COXI COXII COXIII CYC CYCS DDIT4 EIF2C1 EIF2C2 EIF2C3 EIF2C4 FAM36A FRAP FRAP1 FRAP2 G6PD GA GBL GLS GLS1 GLS2 GPI GPX2 GRIM12 HBXIP HME1 Hi95 KDRF KET KIAA0243 KIAA0838 KIAA1093 KIAA1303 KIAA1460 KIAA1567 KIAA1582 KIAA1631 LAMTOR1 LAMTOR2 LAMTOR3 LAMTOR4 LAMTOR5 LRP130 LRPPRC LST8 MAP2K1IP1 MAPBPIP MAPKSP1 MLST8 MMAC1 MOV10 MT-CO1 MT-CO2 MT-CO3 MTCO1 MTCO2 MTCO3 MTOR NDUFA4 NKEFB OXA1L2 P53 P53R2 P63 P73H P73L PAGA PAGB PDRO PKB PKBG PRDX1 PRDX2 PRKAA1 PRKAA2 PRKAB1 PRKAB2 PRKAG1 PRKAG2 PRKAG3 PTEN RAC RAFT1 RAPT1 RAPTOR REDD1 RHEB RHEB2 ROBLD3 RPTOR RRAGA RRAGB RRAGC RRAGD RRM2B RTP801 SCO1 SCO2 SCOD1 SESN2 SESN3 SEST2 SEST3 SFN SLC38A9 SURF-1 SURF1 TACO1 TDPX1 TDPX2 TEP1 TIGAR TNRC6 TNRC6A TNRC6B TNRC6C TP53 TP63 TP73L TRDX TRX TRX1 TSC TSC1 TSC2 TSC4 TXN TXNRD1 URLC11 XIP YWHA1 YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ	Homo sapiens (human)
HATs acetylate histones	Actin, cytoplasmic 1 Actin-like protein 6A Ataxin-7-like protein 3 Ataxin-7 Bromodomain and PHD finger-containing protein 3 Bromodomain-containing protein 1 Bromodomain-containing protein 8 CREB-binding protein Chromatin modification-related protein MEAF6 Circadian locomoter output cycles protein kaput Cyclic AMP-dependent transcription factor ATF-2 Cysteine-rich protein 2-binding protein DNA methyltransferase 1-associated protein 1 E1A-binding protein p400 E3 ubiquitin-protein ligase Jade-2 E3 ubiquitin-protein ligase MSL2 Elongator complex protein 1 Elongator complex protein 2 Elongator complex protein 3 Elongator complex protein 4 Elongator complex protein 5 Elongator complex protein 6 Enhancer of polycomb homolog 1 Histone H2A type 1-A Histone H2A type 1-B/E Histone H2A type 1-C Histone H2A type 1-D Histone H2A type 1-H Histone H2A type 1-J Histone H2A type 1 Histone H2A type 2-A Histone H2A type 2-B Histone H2A type 2-C Histone H2A type 3 Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/F/G/I Histone H2B type 1-D Histone H2B type 1-H Histone H2B type 1-J Histone H2B type 1-K Histone H2B type 1-L Histone H2B type 1-M Histone H2B type 1-N Histone H2B type 1-O Histone H2B type 2-E Histone H2B type 2-F Histone H2B type 3-B Histone H3.1 Histone H3.2 Histone H4 Histone acetyltransferase KAT2A Histone acetyltransferase KAT2B Histone acetyltransferase KAT5 Histone acetyltransferase KAT6A Histone acetyltransferase KAT6B Histone acetyltransferase KAT7 Histone acetyltransferase KAT8 Histone acetyltransferase p300 Histone acetyltransferase type B catalytic subunit Histone deacetylase complex subunit SAP130 Histone-binding protein RBBP7 Host cell factor 1 Inhibitor of growth protein 3 Inhibitor of growth protein 4 Inhibitor of growth protein 5 KAT8 regulatory NSL complex subunit 1 KAT8 regulatory NSL complex subunit 2 KAT8 regulatory NSL complex subunit 3 MAP3K12-binding inhibitory protein 1 MRG/MORF4L-binding protein MSL complex subunit 3 Male-specific lethal 1 homolog Microspherule protein 1 Mortality factor 4-like protein 1 Mortality factor 4-like protein 2 Nuclear receptor coactivator 1 Nuclear receptor coactivator 2 PHD finger protein 20 Paired box protein Pax-3 Peregrin Protein Dr1 Protein Jade-1 Protein Jade-3 RuvB-like 1 RuvB-like 2 SAGA-associated factor 29 STAGA complex 65 subunit gamma TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L Transcription and mRNA export factor ENY2 Transcription factor SPT20 homolog Transcription initiation factor TFIID subunit 10 Transcription initiation factor TFIID subunit 12 Transcription initiation factor TFIID subunit 9 Transcription initiation protein SPT3 homolog Transcriptional adapter 1 Transcriptional adapter 2-alpha Transcriptional adapter 2-beta Transcriptional adapter 3 Transformation/transcription domain-associated protein UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit Ubiquitin carboxyl-terminal hydrolase 22 Vacuolar protein sorting-associated protein 72 homolog WD repeat-containing protein 5 YEATS domain-containing protein 2 YEATS domain-containing protein 4 ZZ-type zinc finger-containing protein 3	O14929 O15265 O15294 O15516 O60814 O75478 O75486 O75528 O75529 O94864 O95163 O95251 O95619 O95696 O96019 P04908 P06899 P0C0S8 P15336 P20671 P23527 P23760 P33778 P51610 P55201 P58876 P60709 P61964 P62805 P62807 P68431 Q01658 Q09472 Q0PNE2 Q12962 Q14CW9 Q15014 Q15596 Q15788 Q15906 Q16514 Q16576 Q16594 Q16777 Q16778 Q5QNW6 Q68DK7 Q6FI13 Q6IA86 Q6IE81 Q71DI3 Q7L7L0 Q7Z3B3 Q86TJ2 Q8IUE6 Q8IYH5 Q8N257 Q8N5Y2 Q8NEM7 Q8TE02 Q8WYB5 Q8WYH8 Q92613 Q92793 Q92794 Q92830 Q92831 Q92993 Q93077 Q93079 Q96A08 Q96BN2 Q96EB1 Q96ES7 Q96EZ8 Q96KK5 Q96L91 Q96QV6 Q99877 Q99878 Q99879 Q99880 Q9BVI0 Q9H0E3 Q9H0E9 Q9H2F5 Q9H7Z6 Q9H8E8 Q9H9L4 Q9H9T3 Q9HAF1 Q9HCI7 Q9NPA8 Q9NPF5 Q9NQC1 Q9NS73 Q9NV56 Q9NXR8 Q9P2N6 Q9UBU8 Q9ULD4 Q9ULM3 Q9UNL4 Q9UPT9 Q9Y230 Q9Y265 Q9Y4A5 Q9Y6J9	ACTB ACTL6A ADA2B ADA3 ATF2 ATP1 ATXN7 ATXN7L3 BAF53 BAF53A BHLHE74 BHLHE75 BHLHE8 BIG3 BR140 BRD1 BRD8 BRL BRPF1 BRPF2 BRPF3 C11orf19 C12orf41 C13orf19 C17orf81 C1orf149 C20orf104 C20orf20 C3orf75 CAGH32 CBP CCDC101 CENP-28 CENP-36 CLOCK CREB2 CREBBP CREBP1 CSRP2BP DERP6 DMAP1 DR1 EAF6 ELP1 ELP2 ELP3 ELP4 ELP5 ELP6 ENY2 EP300 EP400 EPC1 FAM48A GAS41 GCN5 GCN5L2 GLEA2 H2AC1 H2AC11 H2AC12 H2AC13 H2AC14 H2AC15 H2AC16 H2AC17 H2AC18 H2AC19 H2AC20 H2AC21 H2AC25 H2AC4 H2AC6 H2AC7 H2AC8 H2AFA H2AFC H2AFD H2AFE H2AFG H2AFI H2AFL H2AFM H2AFN H2AFO H2AFP H2AFQ H2AFR H2AW H2BC1 H2BC10 H2BC11 H2BC12 H2BC13 H2BC14 H2BC15 H2BC17 H2BC18 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H2BFA H2BFB H2BFC H2BFD H2BFE H2BFF H2BFG H2BFH H2BFJ H2BFK H2BFL H2BFN H2BFQ H2BFR H2BFT H2BU1 H3C1 H3C10 H3C11 H3C12 H3C13 H3C14 H3C15 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 H3F2 H3FA H3FB H3FC HIST1H3C H3FD H3FF H3FH H3FI H3FJ H3FK H3FL H3FM H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HAT1 HBO1 HBOa HCA58 HCF1 HCFC1 HFC1 HIRIP1 HIRIP2 HIST1H2AA HIST1H2AB HIST1H2AC HIST1H2AD HIST1H2AE HIST1H2AG HIST1H2AH HIST1H2AI HIST1H2AJ HIST1H2AK HIST1H2AL HIST1H2AM HIST1H2BA HIST1H2BB HIST1H2BC HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2BI HIST1H2BJ HIST1H2BK HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST1H3A HIST1H3B HIST1H3D HIST1H3E HIST1H3F HIST1H3G HIST1H3H HIST1H3I HIST1H3J HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H2AA HIST2H2AA3 HIST2H2AA4 HIST2H2AB HIST2H2AC HIST2H2BE HIST2H2BF HIST2H3A HIST2H3C HIST2H3D HIST2H4 HIST2H4A HIST2H4B HIST3H2A HIST3H2BB HIST4H4 HTATIP HUP2 IKAP IKBKAP ING3 ING4 ING5 INO80H INO80J INO80K INO80Q JADE1 JADE2 JADE3 KANSL1 KANSL2 KANSL3 KAT1 KAT14 KAT2A KAT2B KAT5 KAT6A KAT6B KAT7 KAT8 KIAA0026 KIAA0215 KIAA0239 KIAA0334 KIAA0383 KIAA0764 KIAA1063 KIAA1197 KIAA1267 KIAA1286 KIAA1310 KIAA1425 KIAA1498 KIAA1585 KIAA1807 KIAA1818 MBIP MCRS1 MEAF6 MOF MORF MORF4L1 MORF4L2 MOZ MOZ2 MRG15 MRGBP MRGX MSL1 MSL1L1 MSL1V1 MSL2 MSL2L1 MSL3 MSL3L1 MSP58 MYST1 MYST2 MYST3 MYST4 NCOA1 NCOA2 NMP238 NSL1 NSL2 NSL3 NZF OGT P300 PAF400 PAF65A PAF65B PAX3 PAXNEB PCAF PHF15 PHF16 PHF17 PHF20 PRTD RBAP46 RBBP7 RNF184 RUNXBP2 RUVBL1 RUVBL2 SAP130 SCA7 SGF29 SI1 SMAP SMAP2 SPT3 SRC1 SRC2 STATIP1 SUPT20H SUPT3H SUPT7L TADA1 TADA1L TADA2A TADA2B TADA2L TADA3 TADA3L TAF10 TAF12 TAF15 TAF2A TAF2G TAF2H TAF2J TAF5L TAF6L TAF9 TAFII20 TAFII30 TAFII31 TCFL1 TIF2 TIP48 TIP49 TIP49A TIP49B TIP60 TMEM103 TNRC12 TRRAP TSH2B TZP USP22 USP3L VPS72 WDR5 YEATS2 YEATS4 YL1 ZNF220 ZZZ3	Homo sapiens (human)
ESR-mediated signaling	Estrogen receptor beta Estrogen receptor Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Peptidyl-prolyl cis-trans isomerase D Peptidyl-prolyl cis-trans isomerase FKBP4 Peptidyl-prolyl cis-trans isomerase FKBP5 Prostaglandin E synthase 3 Serine/threonine-protein phosphatase 5	P03372 P07900 P08238 P27361 P28482 P53041 Q02790 Q08752 Q13451 Q15185 Q92731	AIG6 CYP40 CYPD ERK1 ERK2 ESR ESR1 ESR2 ESTRB FKBP4 FKBP5 FKBP51 FKBP52 HSP90A HSP90AA1 HSP90AB1 HSP90B HSPC1 HSPC2 HSPC3 HSPCA HSPCB MAPK1 MAPK3 NR3A1 NR3A2 P23 PPID PPP5 PPP5C PRKM1 PRKM2 PRKM3 PTGES3 TEBP	Homo sapiens (human)
Abortive elongation of HIV-1 transcript in the absence of Tat	DNA-directed RNA polymerase II subunit RPB11-a DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 General transcription factor IIF subunit 1 General transcription factor IIF subunit 2 Negative elongation factor A Negative elongation factor B Negative elongation factor C/D Negative elongation factor E Nuclear cap-binding protein subunit 1 Nuclear cap-binding protein subunit 2 RNA polymerase II subunit A C-terminal domain phosphatase Transcription elongation factor SPT4 Transcription elongation factor SPT5	O00267 O15514 P13984 P18615 P19387 P19388 P24928 P30876 P35269 P36954 P52298 P52434 P52435 P53803 P61218 P62487 P62875 P63272 Q09161 Q8IXH7 Q8WX92 Q9H3P2 Q9Y5B0	CBP20 CBP80 COBRA1 CTDP1 FCP1 GTF2F1 GTF2F2 KIAA1182 NCBP NCBP1 NCBP2 NELFA NELFB NELFCD NELFD NELFE POLR2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J1 POLR2K POLR2L POLRF RAP30 RAP74 RD RDBP RPB7 SPT4H SPT5 SPT5H SUPT4H SUPT4H1 SUPT5H TH1 TH1L WHSC2	Homo sapiens (human)
Highly sodium permeable postsynaptic acetylcholine nicotinic receptors	Acetylcholine receptor subunit delta Acetylcholine receptor subunit epsilon Acetylcholine receptor subunit gamma Neuronal acetylcholine receptor subunit alpha-3 Neuronal acetylcholine receptor subunit alpha-4 Neuronal acetylcholine receptor subunit beta-2 Neuronal acetylcholine receptor subunit beta-4	P07510 P17787 P30926 P32297 P43681 Q04844 Q07001	ACHRD ACHRE ACHRG CHRNA3 CHRNA4 CHRNB2 CHRNB4 CHRND CHRNE CHRNG NACHRA3 NACRA4	Homo sapiens (human)
MGMT-mediated DNA damage reversal	Methylated-DNA--protein-cysteine methyltransferase	P16455	MGMT	Homo sapiens (human)
Integrin signaling	3-phosphoinositide-dependent protein kinase 1 Amyloid beta A4 precursor protein-binding family B member 1-interacting protein Fibrinogen alpha chain Fibrinogen beta chain Fibrinogen gamma chain Fibronectin Focal adhesion kinase 1 Integrin alpha-IIb Integrin beta-3 Proto-oncogene tyrosine-protein kinase Src RAC-alpha serine/threonine-protein kinase RAS guanyl-releasing protein 1 RAS guanyl-releasing protein 2 Rap guanine nucleotide exchange factor 3 Rap guanine nucleotide exchange factor 4 Ras-related protein Rap-1A Ras-related protein Rap-1b SHC-transforming protein 1 Talin-1 Tyrosine-protein kinase CSK Tyrosine-protein kinase SYK Tyrosine-protein phosphatase non-receptor type 1 von Willebrand factor	O15530 O95267 O95398 P02671 P02675 P02679 P02751 P04275 P05106 P08514 P12931 P18031 P29353 P31749 P41240 P43405 P61224 P62834 Q05397 Q7LDG7 Q7Z5R6 Q8WZA2 Q9Y490	AKT1 APBB1IP CDC25L CGEF1 CGEF2 CSK EPAC EPAC1 EPAC2 F8VWF FAK FAK1 FGA FGB FGG FN FN1 GP2B GP3A ITGA2B ITGAB ITGB3 KIAA1027 KREV1 MCG7 PDK1 PDPK1 PKB PREL1 PTK2 PTP1B PTPN1 RAC RAP1A RAP1B RAPGEF3 RAPGEF4 RARP1 RASGRP RASGRP1 RASGRP2 RIAM SHC SHC1 SHCA SRC SRC1 SYK TLN TLN1 VWF	Homo sapiens (human)
MTOR signalling	14-3-3 protein beta/alpha GTP-binding protein Rheb Neutral amino acid transporter 9 Proline-rich AKT1 substrate 1 RAC-alpha serine/threonine-protein kinase Ragulator complex protein LAMTOR1 Ragulator complex protein LAMTOR2 Ragulator complex protein LAMTOR3 Ragulator complex protein LAMTOR4 Ragulator complex protein LAMTOR5 Ras-related GTP-binding protein A Ras-related GTP-binding protein B Ras-related GTP-binding protein C Ras-related GTP-binding protein D Regulatory-associated protein of mTOR Serine/threonine-protein kinase mTOR Target of rapamycin complex subunit LST8	O43504 P31749 P31946 P42345 Q0VGL1 Q15382 Q5VZM2 Q6IAA8 Q7L523 Q8N122 Q8NBW4 Q96B36 Q9BVC4 Q9HB90 Q9NQL2 Q9UHA4 Q9Y2Q5	AKT1 AKT1S1 C11orf59 C7orf59 FRAP FRAP1 FRAP2 GBL HBXIP KIAA1303 LAMTOR1 LAMTOR2 LAMTOR3 LAMTOR4 LAMTOR5 LST8 MAP2K1IP1 MAPBPIP MAPKSP1 MLST8 MTOR PDRO PKB PRAS40 RAC RAFT1 RAPT1 RAPTOR RHEB RHEB2 ROBLD3 RPTOR RRAGA RRAGB RRAGC RRAGD SLC38A9 URLC11 XIP YWHAB	Homo sapiens (human)

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