GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **1526 - 1550** of **2090** in total

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Pathway Name ▲	Protein Name	UniProt ID	Gene Symbol	Organism	GlyTouCan ID
Regulation of activated PAK-2p34 by proteasome mediated degradation	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Serine/threonine-protein kinase PAK 2 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A5LHX3 O00231 O00232 O00233 O00487 O14818 O43242 O75832 P0CG47 P0CG48 P17980 P20618 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P35998 P40306 P43686 P48556 P49720 P49721 P51665 P55036 P60896 P60900 P61289 P62191 P62195 P62333 P62979 P62987 Q06323 Q13177 Q13200 Q14997 Q15008 Q16401 Q8TAA3 Q92530 Q99436 Q99460 Q9UL46 Q9UNM6	C7orf76 DSS1 HC2 HC3 HC8 HC9 HSPC IFI5111 KIAA0072 KIAA0077 KIAA0107 LMP10 LMP2 LMP7 LMPX LMPY MB1 MCB1 MECL1 MIP224 MOV34L MSS1 NU PAK2 PFAAP4 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 RING10 RING12 RPS27A SEM1 SHFDG1 SHFM1 SUG1 SUG2 TBP1 TBP7 TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 X Y Y2 Z	Homo sapiens (human)
Regulation of cholesterol biosynthesis by SREBP (SREBF)	GTP-binding nuclear protein Ran Importin subunit beta-1 Insulin-induced gene 1 protein Insulin-induced gene 2 protein Membrane-bound transcription factor site-1 protease Membrane-bound transcription factor site-2 protease Protein transport protein Sec23A Protein transport protein Sec24A Protein transport protein Sec24B Protein transport protein Sec24C Protein transport protein Sec24D Small COPII coat GTPase SAR1B Sterol regulatory element-binding protein 2 Sterol regulatory element-binding protein cleavage-activating protein	O15503 O43462 O94855 O95486 O95487 P53992 P62826 Q12770 Q12772 Q14703 Q14974 Q15436 Q9Y5U4 Q9Y6B6	ARA24 BHLHD2 INSIG1 INSIG2 KIAA0079 KIAA0091 KIAA0199 KIAA0755 KPNB1 MBTPS1 MBTPS2 NTF97 RAN S1P S2P SAR1B SARA2 SARB SCAP SEC23A SEC24A SEC24B SEC24C SEC24D SKI1 SREBF2 SREBP2	Homo sapiens (human)
Regulation of commissural axon pathfinding by SLIT and ROBO	Netrin receptor DCC Netrin-1 Protein kinase C-binding protein NELL2 Proto-oncogene tyrosine-protein kinase Src Roundabout homolog 1 Roundabout homolog 2 Slit homolog 1 protein Slit homolog 2 protein Slit homolog 3 protein	O75093 O75094 O94813 O95631 P12931 P43146 Q99435 Q9HCK4 Q9Y6N7	DCC DUTT1 IGDCC1 KIAA0813 KIAA0814 KIAA1568 MEGF4 MEGF5 NELL2 NRP2 NTN1 NTN1L ROBO1 ROBO2 SLIL1 SLIL2 SLIL3 SLIT1 SLIT2 SLIT3 SRC SRC1	Homo sapiens (human)
Regulation of cortical dendrite branching	Cytoplasmic protein NCK2 Roundabout homolog 1 Roundabout homolog 2 Slit homolog 1 protein	O43639 O75093 Q9HCK4 Q9Y6N7	DUTT1 GRB4 KIAA0813 KIAA1568 MEGF4 NCK2 ROBO1 ROBO2 SLIL1 SLIT1	Homo sapiens (human)
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components	Alpha-actinin-1 Alpha-parvin Beta-parvin Dual specificity testis-specific protein kinase 1 LIM and senescent cell antigen-like-containing domain protein 1 Paxillin Ras suppressor protein 1 Rho guanine nucleotide exchange factor 6	P12814 P48059 P49023 Q15052 Q15404 Q15569 Q9HBI1 Q9NVD7	ACTN1 ARHGEF6 COOL2 KIAA0006 LIMS1 MXRA2 PARVA PARVB PINCH PINCH1 PIXA PXN RSP1 RSU1 TESK1	Homo sapiens (human)
Regulation of expression of SLITs and ROBOs	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Collagen alpha-5(IV) chain Cullin-2 Dystroglycan 1 E3 ubiquitin-protein ligase RBX1 Elongin-B Elongin-C Eukaryotic initiation factor 4A-III Eukaryotic peptide chain release factor GTP-binding subunit ERF3A Eukaryotic peptide chain release factor GTP-binding subunit ERF3B Eukaryotic peptide chain release factor subunit 1 Eukaryotic translation initiation factor 4 gamma 1 Homeobox protein Hox-A2 Insulin gene enhancer protein ISL-1 LIM domain-binding protein 1 LIM/homeobox protein Lhx2 LIM/homeobox protein Lhx3 LIM/homeobox protein Lhx4 LIM/homeobox protein Lhx9 Large ribosomal subunit protein P1 Large ribosomal subunit protein P2 Large ribosomal subunit protein eL13 Large ribosomal subunit protein eL14 Large ribosomal subunit protein eL15 Large ribosomal subunit protein eL18 Large ribosomal subunit protein eL19 Large ribosomal subunit protein eL20 Large ribosomal subunit protein eL21 Large ribosomal subunit protein eL22 Large ribosomal subunit protein eL24 Large ribosomal subunit protein eL27 Large ribosomal subunit protein eL28 Large ribosomal subunit protein eL29 Large ribosomal subunit protein eL30 Large ribosomal subunit protein eL31 Large ribosomal subunit protein eL32 Large ribosomal subunit protein eL33 Large ribosomal subunit protein eL34 Large ribosomal subunit protein eL36 Large ribosomal subunit protein eL37 Large ribosomal subunit protein eL38 Large ribosomal subunit protein eL39 Large ribosomal subunit protein eL42 Large ribosomal subunit protein eL43 Large ribosomal subunit protein eL6 Large ribosomal subunit protein eL8 Large ribosomal subunit protein uL10 Large ribosomal subunit protein uL11 Large ribosomal subunit protein uL13 Large ribosomal subunit protein uL14 Large ribosomal subunit protein uL15 Large ribosomal subunit protein uL16 Large ribosomal subunit protein uL18 Large ribosomal subunit protein uL1 Large ribosomal subunit protein uL22 Large ribosomal subunit protein uL23 Large ribosomal subunit protein uL24 Large ribosomal subunit protein uL29 Large ribosomal subunit protein uL2 Large ribosomal subunit protein uL30 Large ribosomal subunit protein uL3 Large ribosomal subunit protein uL4 Large ribosomal subunit protein uL5 Large ribosomal subunit protein uL6 Nuclear cap-binding protein subunit 1 Nuclear cap-binding protein subunit 2 Polyadenylate-binding protein 1 Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Protein CASC3 Protein mago nashi homolog 2 Protein mago nashi homolog RNA-binding protein 8A RNA-binding protein Musashi homolog 1 RNA-binding protein with serine-rich domain 1 Regulator of nonsense transcripts 2 Regulator of nonsense transcripts 3A Regulator of nonsense transcripts 3B Ribosomal protein eL22-like Ribosomal protein eL39-like 2 Ribosomal protein eL42-like Ribosomal protein eS27-like Ribosomal protein uL16-like Ribosomal protein uL24-like Ribosomal protein uL3-like Roundabout homolog 1 Roundabout homolog 2 Slit homolog 1 protein Slit homolog 2 protein Small ribosomal subunit protein eS10 Small ribosomal subunit protein eS12 Small ribosomal subunit protein eS17 Small ribosomal subunit protein eS19 Small ribosomal subunit protein eS1 Small ribosomal subunit protein eS21 Small ribosomal subunit protein eS24 Small ribosomal subunit protein eS25 Small ribosomal subunit protein eS26 Small ribosomal subunit protein eS27 Small ribosomal subunit protein eS28 Small ribosomal subunit protein eS32 Small ribosomal subunit protein eS4, X isoform Small ribosomal subunit protein eS4, Y isoform 1 Small ribosomal subunit protein eS4, Y isoform 2 Small ribosomal subunit protein eS6 Small ribosomal subunit protein eS7 Small ribosomal subunit protein eS8 Small ribosomal subunit protein uS10 Small ribosomal subunit protein uS11 Small ribosomal subunit protein uS12 Small ribosomal subunit protein uS13 Small ribosomal subunit protein uS14 Small ribosomal subunit protein uS15 Small ribosomal subunit protein uS17 Small ribosomal subunit protein uS19 Small ribosomal subunit protein uS2 Small ribosomal subunit protein uS3 Small ribosomal subunit protein uS4 Small ribosomal subunit protein uS5 Small ribosomal subunit protein uS7 Small ribosomal subunit protein uS8 Small ribosomal subunit protein uS9 Ubiquitin carboxyl-terminal hydrolase 33 Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Zinc finger SWIM domain-containing protein 8	A5LHX3 A7E2V4 O00231 O00232 O00233 O00487 O14818 O15234 O43242 O43347 O43364 O75093 O75832 O94813 P05386 P05387 P05388 P08708 P08865 P0CG47 P0CG48 P11940 P15170 P15880 P17980 P18077 P18124 P18621 P20618 P22090 P23396 P25398 P25786 P25787 P25788 P25789 P26373 P27635 P28062 P28065 P28066 P28070 P28072 P28074 P29400 P30050 P32969 P35268 P35998 P36578 P38919 P39019 P39023 P40306 P40429 P42677 P42766 P43686 P46776 P46777 P46778 P46779 P46781 P46782 P46783 P47914 P48556 P49207 P49720 P49721 P50458 P50914 P51665 P52298 P55036 P60866 P60896 P60900 P61247 P61254 P61289 P61313 P61326 P61353 P61371 P61513 P61927 P62081 P62191 P62195 P62241 P62244 P62249 P62263 P62266 P62269 P62273 P62277 P62280 P62333 P62424 P62495 P62701 P62750 P62753 P62829 P62841 P62847 P62851 P62854 P62857 P62861 P62877 P62888 P62891 P62899 P62906 P62910 P62913 P62917 P62945 P62979 P62987 P63173 P63220 P83731 P83881 P84098 Q02543 Q02878 Q04637 Q06323 Q07020 Q09161 Q13200 Q13617 Q14118 Q14997 Q15008 Q15287 Q15369 Q15370 Q16401 Q6P5R6 Q71UM5 Q86U70 Q8IYD1 Q8TAA3 Q8TD47 Q8TEY7 Q92530 Q92901 Q969G2 Q969Q0 Q96A72 Q96EH5 Q96L21 Q99436 Q99460 Q9BZI7 Q9H1J1 Q9HAU5 Q9HCK4 Q9NQ69 Q9UBR4 Q9UL46 Q9UNM6 Q9UNX3 Q9Y3U8 Q9Y5S9 Q9Y6N7	BBC1 C7orf76 CASC3 CBP20 CBP80 CCG2 CLIM2 COL4A5 CUL2 D11S2243E D6S218E DAG1 DDX48 DSS1 DUTT1 DXS648E EC45 EIF4A3 EIF4F EIF4G EIF4G1 EIF4GI ELOB ELOC ERF1 ERF3A ERF3B ETF1 FAU FTE1 GSPT1 GSPT2 HC2 HC3 HC8 HC9 HOX1K HOXA2 HSPC IFI5111 ISL1 KIAA0072 KIAA0077 KIAA0107 KIAA0111 KIAA0813 KIAA0913 KIAA1097 KIAA1408 KIAA1568 LAMBR LAMR1 LDB1 LDC2 LH2 LHX2 LHX3 LHX4 LHX9 LMP10 LMP2 LMP7 LMPX LMPY MAGOH MAGOH2 MAGOHA MAGOHB MB1 MCB1 MECL1 MEGF4 MFTL MIP224 MLN51 MOV34L MPS1 MSI1 MSS1 NCBP NCBP1 NCBP2 NEDD6 NU PAB1 PABP PABP1 PABPC1 PABPC2 PFAAP4 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 QM RBM8 RBM8A RBX1 RENT2 RENT3A RENT3B RF1 RIG RING10 RING12 RNF75 RNPS1 ROBO1 ROBO2 ROC1 RPL1 RPL10 RPL10A RPL10L RPL11 RPL12 RPL13 RPL13A RPL14 RPL15 RPL17 RPL18 RPL18A RPL19 RPL21 RPL22 RPL22L1 RPL23 RPL23A RPL24 RPL26 RPL26L1 RPL26P1 RPL27 RPL27A RPL28 RPL29 RPL3 RPL30 RPL31 RPL32 RPL34 RPL35 RPL35A RPL36 RPL36A RPL36AL RPL37 RPL37A RPL38 RPL39 RPL39L RPL39L1 RPL3L RPL4 RPL41 RPL44 RPL5 RPL6 RPL7 RPL7A RPL8 RPL9 RPL9P7 RPL9P8 RPL9P9 RPLP0 RPLP1 RPLP2 RPP2 RPS10 RPS11 RPS12 RPS13 RPS14 RPS15 RPS15A RPS16 RPS17 RPS17L RPS18 RPS19 RPS2 RPS20 RPS21 RPS23 RPS24 RPS25 RPS26 RPS27 RPS27A RPS27L RPS28 RPS29 RPS3 RPS3A RPS4 RPS4X RPS4Y RPS4Y1 RPS4Y2 RPS4Y2P RPS5 RPS6 RPS7 RPS8 RPS9 RPSA RRP1 SCAR SEM1 SHFDG1 SHFM1 SLIL1 SLIL3 SLIT1 SLIT2 SUG1 SUG2 SUP45L1 SURF-3 SURF3 TBP1 TBP7 TCEB1 TCEB2 TRAP2 TXREB1 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 UPF2 UPF3 UPF3A UPF3B UPF3X USP33 VDU1 X Y Y2 Z ZSWIM8	Homo sapiens (human)
Regulation of gap junction activity	Envelope small membrane protein Gap junction alpha-1 protein Tight junction protein ZO-1	P0DTC4 P17302 Q07157	E GJA1 GJAL TJP1 ZO1	Homo sapiens (human)
Regulation of gene expression by Hypoxia-inducible Factor	Aryl hydrocarbon receptor nuclear translocator CREB-binding protein Carbonic anhydrase 9 Cbp/p300-interacting transactivator 2 Endothelial PAS domain-containing protein 1 Erythropoietin HIG1 domain family member 1A, mitochondrial Histone acetyltransferase p300 Hypoxia-inducible factor 1-alpha Vascular endothelial growth factor A, long form	P01588 P15692 P27540 Q09472 Q16665 Q16790 Q92793 Q99814 Q99967 Q9Y241	ARNT BHLHE2 BHLHE73 BHLHE78 CA9 CBP CITED2 CREBBP EP300 EPAS1 EPO G250 HIF1A HIF2A HIG1 HIGD1A MN MOP1 MOP2 MRG1 P300 PASD2 PASD8 VEGF VEGFA	Homo sapiens (human)
Regulation of gene expression in beta cells	DNA-binding protein RFX6 Forkhead box protein O1 Hepatocyte nuclear factor 1-alpha Hepatocyte nuclear factor 3-beta Hepatocyte nuclear factor 3-gamma Hepatocyte nuclear factor 4-gamma Hexokinase-4 Homeobox protein Nkx-2.2 Homeobox protein Nkx-6.1 Insulin Islet amyloid polypeptide Neurogenic differentiation factor 1 Paired box protein Pax-6 Pancreas/duodenum homeobox protein 1 Solute carrier family 2, facilitated glucose transporter member 2 Transcription factor MafA	O95096 P01308 P10997 P11168 P20823 P26367 P35557 P52945 P55318 P78426 Q12778 Q13562 Q14541 Q8HWS3 Q8NHW3 Q9Y261	AN2 BHLHA3 FKHR FOXA2 FOXA3 FOXO1 FOXO1A GCK GLUT2 HNF1A HNF3B HNF3G HNF4G IAPP INS IPF1 MAFA NEUROD NEUROD1 NKX2-2 NKX2.2 NKX2B NKX6-1 NKX6A NR2A2 PAX6 PDX1 RFX6 RFXDC1 SLC2A2 STF1 TCF1 TCF3B TCF3G	Homo sapiens (human)
Regulation of gene expression in early pancreatic precursor cells	Fibroblast growth factor 10 Hepatocyte nuclear factor 1-beta Hepatocyte nuclear factor 6 Homeobox protein Nkx-6.1 One cut domain family member 3 Pancreas transcription factor 1 subunit alpha Pancreas/duodenum homeobox protein 1	O15520 O60422 P35680 P52945 P78426 Q7RTS3 Q9UBC0	BHLHA29 FGF10 HNF1B HNF6 HNF6A IPF1 NKX6-1 NKX6A ONECUT1 ONECUT3 PDX1 PTF1A PTF1P48 STF1 TCF2	Homo sapiens (human)
Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells	Homeobox protein Nkx-2.2 Insulinoma-associated protein 1 Neurogenic differentiation factor 1 Neurogenin-3 Paired box protein Pax-4	O43316 O95096 Q01101 Q13562 Q9Y4Z2	ATOH5 BHLHA3 BHLHA7 IA1 INSM1 NEUROD NEUROD1 NEUROG3 NGN3 NKX2-2 NKX2.2 NKX2B PAX4	Homo sapiens (human)
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells	CREB-binding protein Hepatocyte nuclear factor 1-beta Hepatocyte nuclear factor 6 Histone acetyltransferase KAT2A Histone acetyltransferase KAT2B Histone acetyltransferase p300 Mastermind-like domain-containing protein 1 Mastermind-like protein 1 Mastermind-like protein 2 Mastermind-like protein 3 Neurogenic locus notch homolog protein 1 Neurogenin-3 One cut domain family member 3 Recombining binding protein suppressor of hairless SNW domain-containing protein 1 Transcription factor HES-1	O60422 P35680 P46531 Q06330 Q09472 Q13495 Q13573 Q14469 Q8IZL2 Q92585 Q92793 Q92830 Q92831 Q96JK9 Q9UBC0 Q9Y4Z2	ATOH5 BHLHA7 BHLHB39 CBP CG1 CREBBP CXorf6 EP300 GCN5 GCN5L2 HES1 HL HNF1B HNF6 HNF6A HRY IGKJRB IGKJRB1 KAT2A KAT2B KIAA0200 KIAA1816 KIAA1819 MAML1 MAML2 MAML3 MAMLD1 NEUROG3 NGN3 NOTCH1 ONECUT1 ONECUT3 P300 PCAF RBPJ RBPJK RBPSUH SKIIP SKIP SNW1 TAN1 TCF2	Homo sapiens (human)
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism	6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit gamma	O60825 P16118 P17612 P22612 P22694 P30153 P30154 P62714 P67775 Q14738 Q16875 Q16877	F6PK PFKFB1 PFKFB2 PFKFB3 PFKFB4 PFRX PKACA PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5D PRKACA PRKACB PRKACG	Homo sapiens (human)
Regulation of innate immune responses to cytosolic DNA	E3 ubiquitin-protein ligase DTX4 E3 ubiquitin-protein ligase TRIM21 E3 ubiquitin-protein ligase TRIM32 E3 ubiquitin-protein ligase TRIM56 Interferon regulatory factor 3 NACHT, LRR and PYD domains-containing protein 4 Polyubiquitin-B Polyubiquitin-C Probable ATP-dependent RNA helicase DDX41 Serine/threonine-protein kinase TBK1 Stimulator of interferon genes protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Z-DNA-binding protein 1	P0CG47 P0CG48 P19474 P62979 P62987 Q13049 Q14653 Q86WV6 Q96MN2 Q9BRZ2 Q9H171 Q9UHD2 Q9UJV9 Q9Y2E6	ABS C20orf183 DDX41 DLM1 DTX4 ERIS HT2A IRF3 KIAA0937 MITA NAK NALP4 NLRP4 PAN2 PYPAF4 RNF109 RNF155 RNF81 RNH2 RO52 RPS27A SSA1 STING STING1 TBK1 TMEM173 TRIM21 TRIM32 TRIM56 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 ZBP1	Homo sapiens (human)
Regulation of insulin secretion	ATP-binding cassette sub-family C member 8 ATP-sensitive inward rectifier potassium channel 11 Guanine nucleotide-binding protein G(i) subunit alpha-1 Guanine nucleotide-binding protein G(i) subunit alpha-2 Inositol 1,4,5-trisphosphate receptor type 2 Inositol 1,4,5-trisphosphate receptor type 3 Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1 Insulin Rap guanine nucleotide exchange factor 3 Rap guanine nucleotide exchange factor 4 S-adenosylhomocysteine hydrolase-like protein 1 Solute carrier family 2, facilitated glucose transporter member 1 Solute carrier family 2, facilitated glucose transporter member 2 Synaptosomal-associated protein 25 Synaptotagmin-5 Syntaxin-1A Syntaxin-binding protein 1 Vesicle-associated membrane protein 2 Voltage-dependent L-type calcium channel subunit alpha-1C Voltage-dependent L-type calcium channel subunit alpha-1D Voltage-dependent L-type calcium channel subunit beta-2 Voltage-dependent L-type calcium channel subunit beta-3 Voltage-dependent P/Q-type calcium channel subunit alpha-1A Voltage-dependent R-type calcium channel subunit alpha-1E Voltage-dependent calcium channel subunit alpha-2/delta-2 cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit gamma	O00445 O00555 O43865 O95398 P01308 P04899 P11166 P11168 P17612 P22612 P22694 P54284 P60880 P61764 P63027 P63096 Q01668 Q08289 Q09428 Q13936 Q14571 Q14573 Q14643 Q14654 Q15878 Q16623 Q8WZA2 Q9NY47	ABCC8 AHCYL1 CACH2 CACH3 CACH4 CACH6 CACN2 CACN3 CACN4 CACNA1A CACNA1C CACNA1D CACNA1E CACNA2D2 CACNB2 CACNB3 CACNL1A1 CACNL1A2 CACNL1A4 CACNL1A6 CACNLB2 CACNLB3 CCHL1A1 CCHL1A2 CGEF1 CGEF2 DCAL EPAC EPAC1 EPAC2 GLUT1 GLUT2 GNAI1 GNAI2 GNAI2B HRINS INS INSP3R1 IRBIT ITPR1 ITPR2 ITPR3 KCNJ11 KIAA0558 MYSB PKACA PRKACA PRKACB PRKACG RAPGEF3 RAPGEF4 SLC2A1 SLC2A2 SNAP SNAP25 STX1 STX1A STXBP1 SUR SUR1 SYB2 SYT5 UNC18A VAMP2 XPVKONA	Homo sapiens (human)	G58161NS
Regulation of lipid metabolism by PPARalpha	3'-5' exoribonuclease HELZ2 CREB-binding protein Chromodomain-helicase-DNA-binding protein 9 F-box-like/WD repeat-containing protein TBL1X F-box-like/WD repeat-containing protein TBL1XR1 Fatty acid-binding protein, liver Histone deacetylase 3 Histone-arginine methyltransferase CARM1 Mediator of RNA polymerase II transcription subunit 1 Nuclear receptor coactivator 1 Nuclear receptor coactivator 2 Nuclear receptor coactivator 6 Nuclear receptor corepressor 1 Nuclear receptor corepressor 2 Paired amphipathic helix protein Sin3a Peroxisome proliferator-activated receptor alpha Retinoic acid receptor RXR-alpha SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 Trimethylguanosine synthase	O15379 O60907 O75376 P07148 P19793 Q07869 Q14686 Q15596 Q15648 Q15788 Q3L8U1 Q6STE5 Q86X55 Q92793 Q96RS0 Q96ST3 Q9BYK8 Q9BZK7 Q9Y618	AIB3 ARC205 BAF60C BHLHE74 BHLHE75 CARM1 CBP CHD9 CREBBP CRSP1 CRSP200 CTG26 DRIP205 DRIP230 FABP1 FABPL HCA137 HDAC3 HELZ2 IRA1 KIAA0181 KIAA0308 KIAA1047 KIAA1769 KISH2 MED1 NCOA1 NCOA2 NCOA6 NCOA6IP NCOR1 NCOR2 NR1C1 NR2B1 PBP PIMT PPAR PPARA PPARBP PPARGBP PRIC285 PRIC320 PRMT4 RAP250 RB18A RXRA SIN3A SMARCD3 SRC1 SRC2 TBL1 TBL1X TBL1XR1 TBLR1 TGS1 TIF2 TRAP220 TRBP TRIP2	Homo sapiens (human)
Regulation of localization of FOXO transcription factors	14-3-3 protein beta/alpha 14-3-3 protein gamma 14-3-3 protein sigma 14-3-3 protein theta 14-3-3 protein zeta/delta Forkhead box protein O1 Forkhead box protein O3 Forkhead box protein O4 Forkhead box protein O6 RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase	A8MYZ6 O43524 P27348 P31749 P31751 P31946 P31947 P61981 P63104 P98177 Q12778 Q9Y243	AFX AFX1 AKT1 AKT2 AKT3 FKHR FKHRL1 FOXO1 FOXO1A FOXO3 FOXO3A FOXO4 FOXO6 HME1 MLLT7 PKB PKBG RAC SFN YWHAB YWHAG YWHAQ YWHAZ	Homo sapiens (human)
Regulation of necroptotic cell death	Baculoviral IAP repeat-containing protein 2 Baculoviral IAP repeat-containing protein 3 Caspase-8 E3 ubiquitin-protein ligase CHIP E3 ubiquitin-protein ligase Itchy homolog E3 ubiquitin-protein ligase XIAP E3 ubiquitin-protein ligase parkin E3 ubiquitin-protein ligase pellino homolog 1 FAS-associated death domain protein Flotillin-1 Flotillin-2 Heat shock protein HSP 90-alpha Hsp90 co-chaperone Cdc37 Mixed lineage kinase domain-like protein Polyubiquitin-B Polyubiquitin-C Programmed cell death 6-interacting protein Receptor-interacting serine/threonine-protein kinase 1 Receptor-interacting serine/threonine-protein kinase 3 Syntenin-1 TNF receptor-associated factor 2 Tumor necrosis factor receptor type 1-associated DEATH domain protein UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit Ubiquitin-conjugating enzyme E2 L3 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00560 O15294 O60260 O75955 P07900 P0CG47 P0CG48 P62979 P62987 P68036 P98170 Q12933 Q13158 Q13489 Q13490 Q13546 Q14254 Q14790 Q15628 Q16543 Q8NB16 Q8WUM4 Q96FA3 Q96J02 Q9UNE7 Q9Y572	AIP1 ALIX API1 API2 API3 BIRC2 BIRC3 BIRC4 CASP8 CDC37 CDC37A CHIP ESA1 FADD FLOT1 FLOT2 HSP90A HSP90AA1 HSPC1 HSPCA IAP3 ITCH KIAA1375 M17S1 MCH5 MDA9 MIHB MIHC MLKL MORT1 OGT PARK2 PDCD6IP PELI1 PRISM PRKN RIP RIP1 RIP3 RIPK1 RIPK3 RNF48 RNF49 RPS27A SDCBP STUB1 SYCL TRADD TRAF2 TRAP3 UBA52 UBA80 UBB UBC UBCE7 UBCEP1 UBCEP2 UBCH7 UBE2L3 XIAP	Homo sapiens (human)
Regulation of ornithine decarboxylase (ODC)	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Antizyme inhibitor 1 NAD(P)H dehydrogenase [quinone] 1 Ornithine decarboxylase antizyme 1 Ornithine decarboxylase antizyme 2 Ornithine decarboxylase antizyme 3 Ornithine decarboxylase Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9	A5LHX3 O00231 O00232 O00233 O00487 O14818 O14977 O43242 O75832 O95190 P11926 P15559 P17980 P20618 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P35998 P40306 P43686 P48556 P49720 P49721 P51665 P54368 P55036 P60896 P60900 P61289 P62191 P62195 P62333 Q06323 Q13200 Q14997 Q15008 Q16401 Q8TAA3 Q92530 Q99436 Q99460 Q9UL46 Q9UMX2 Q9UNM6	AZIN1 C7orf76 DIA4 DSS1 HC2 HC3 HC8 HC9 HSPC IFI5111 KIAA0072 KIAA0077 KIAA0107 LMP10 LMP2 LMP7 LMPX LMPY MB1 MCB1 MECL1 MIP224 MOV34L MSS1 NMOR1 NQO1 NU OAZ OAZ1 OAZ2 OAZ3 OAZI OAZIN ODC1 PFAAP4 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 RING10 RING12 SEM1 SHFDG1 SHFM1 SUG1 SUG2 TBP1 TBP7 TRAP2 X Y Y2 Z	Homo sapiens (human)
Regulation of pyruvate dehydrogenase (PDH) complex	Dihydrolipoyl dehydrogenase, mitochondrial Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial Maleylacetoacetate isomerase NAD-dependent protein lipoamidase sirtuin-4, mitochondrial Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial Pyruvate dehydrogenase E1 component subunit beta, mitochondrial Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial Pyruvate dehydrogenase protein X component, mitochondrial [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial	O00330 O43708 P08559 P09622 P10515 P11177 P29803 Q15118 Q15119 Q15120 Q16654 Q8NCN5 Q9P0J1 Q9P2J9 Q9Y6E7	DLAT DLD DLTA GCSL GSTZ1 KIAA1348 KIAA1990 LAD MAAI PDHA1 PDHA2 PDHAL PDHB PDHK1 PDHK2 PDHK3 PDHK4 PDHX PDK1 PDK2 PDK3 PDK4 PDP PDP1 PDP2 PDPR PDX1 PHE1A PHE1B PHE3 PPM2C SIR2L4 SIRT4	Homo sapiens (human)
Regulation of pyruvate metabolism	Armadillo repeat-containing protein 8 E3 ubiquitin-protein transferase MAEA E3 ubiquitin-protein transferase RMND5A E3 ubiquitin-protein transferase RMND5B Glucose-induced degradation protein 4 homolog Glucose-induced degradation protein 8 homolog L-lactate dehydrogenase A chain Muskelin NADP-dependent malic enzyme Polyubiquitin-B Polyubiquitin-C Ran-binding protein 9 Serine/threonine-protein kinase Nek1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein WD repeat-containing protein 26	P00338 P0CG47 P0CG48 P48163 P62979 P62987 Q7L5Y9 Q8IUR7 Q8IVV7 Q96G75 Q96PY6 Q96S59 Q9H7D7 Q9H871 Q9NWU2 Q9UL63	ARMC8 C17orf39 C20orf11 CDW2 EMP GID4 GID8 KIAA1901 LDHA MAEA ME1 MIP2 MKLN1 NEK1 RANBP9 RANBPM RMND5A RMND5B RPS27A TWA1 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 VID24 WDR26	Homo sapiens (human)
Regulation of signaling by CBL	Adapter molecule crk B-cell linker protein Crk-like protein E3 ubiquitin-protein ligase CBL Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 3-kinase regulatory subunit gamma Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform Proto-oncogene vav Rap guanine nucleotide exchange factor 1 Tyrosine-protein kinase Fyn Tyrosine-protein kinase HCK Tyrosine-protein kinase Lyn Tyrosine-protein kinase SYK Tyrosine-protein kinase Yes	O00329 O00459 P06241 P07947 P07948 P08631 P15498 P22681 P27986 P42336 P42338 P43405 P46108 P46109 Q13905 Q8WV28 Q92569	BASH BLNK CBL CBL2 CRK CRKL FYN GRB1 GRF2 HCK JTK8 LYN PIK3C1 PIK3CA PIK3CB PIK3CD PIK3R1 PIK3R2 PIK3R3 RAPGEF1 RNF55 SLP65 SYK VAV VAV1 YES YES1	Homo sapiens (human)
Regulation of signaling by NODAL	Activin receptor type-1B Activin receptor type-1C Activin receptor type-2A Activin receptor type-2B Cerberus Cryptic protein DAN domain family member 5 Left-right determination factor 1 Left-right determination factor 2 Nodal homolog Protein Cripto Putative protein CRIPTO3	O00292 O75610 O95813 P0CG37 P13385 P27037 P36896 P51864 Q13705 Q8N907 Q8NER5 Q96S42	ACVR1B ACVR1C ACVR2 ACVR2A ACVR2B ACVRLK4 ALK4 ALK7 CER1 CER2 CFC1 CKTSF1B3 CRIPTO CRIPTO-1 CRIPTO-3 CRIPTO3 DAND4 DAND5 EBAF GREM3 LEFTA LEFTB LEFTY1 LEFTY2 LEFTYA LEFTYB NODAL SP1 TDGF1 TDGF1P3 TDGF2 TDGF3 TGFB4	Homo sapiens (human)
Regulation of the apoptosome activity	Apoptotic protease-activating factor 1 Caspase recruitment domain-containing protein 8 Caspase-9 Cell death regulator Aven Cytochrome c Diablo IAP-binding mitochondrial protein E3 ubiquitin-protein ligase XIAP Methylthioribulose-1-phosphate dehydratase Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Uveal autoantigen with coiled-coil domains and ankyrin repeats	O14727 P27361 P28482 P55211 P98170 P99999 Q96GX9 Q9BZF9 Q9NQS1 Q9NR28 Q9Y2G2	APAF1 API3 APIP AVEN BIRC4 CARD8 CASP9 CYC CYCS DACAR DIABLO ERK1 ERK2 IAP3 KIAA0413 KIAA0955 KIAA1561 MAPK1 MAPK3 MCH6 NDPP1 PRKM1 PRKM2 PRKM3 SMAC UACA XIAP	Homo sapiens (human)
Relaxin receptors	Insulin-like 3 Insulin-like peptide INSL5 Prorelaxin H2 Relaxin receptor 1 Relaxin receptor 2 Relaxin-3 receptor 1 Relaxin-3 receptor 2 Relaxin-3	P04090 P51460 Q8TDU9 Q8WXD0 Q8WXF3 Q9HBX9 Q9NSD7 Q9Y5Q6	GPCR135 GPCR142 GPR100 GPR106 GREAT INSL3 INSL5 INSL7 LGR7 LGR8 RLF RLN2 RLN3 RLN3R1 RLN3R2 RLNL RXFP1 RXFP2 RXFP3 RXFP4 RXN3 SALPR ZINS4	Homo sapiens (human)

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