GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **1801 - 1825** of **2090** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism ▼
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)	DNA ligase 1 DNA mismatch repair protein Mlh1 DNA mismatch repair protein Msh2 DNA mismatch repair protein Msh6 DNA polymerase delta catalytic subunit DNA polymerase delta subunit 2 DNA polymerase delta subunit 3 DNA polymerase delta subunit 4 Exonuclease 1 Mismatch repair endonuclease PMS2 Proliferating cell nuclear antigen Replication protein A 14 kDa subunit Replication protein A 32 kDa subunit Replication protein A 70 kDa DNA-binding subunit	P12004 P15927 P18858 P27694 P28340 P35244 P40692 P43246 P49005 P52701 P54278 Q15054 Q9HCU8 Q9UQ84	COCA2 EXO1 EXOI GTBP HEX1 KIAA0039 LIG1 MLH1 MSH2 MSH6 PCNA PMS2 PMSL2 POLD POLD1 POLD2 POLD3 POLD4 POLDS REPA1 REPA2 REPA3 RPA1 RPA14 RPA2 RPA3 RPA32 RPA34 RPA70	Homo sapiens (human)
Methionine salvage pathway	Acireductone dioxygenase Aspartate aminotransferase, cytoplasmic Enolase-phosphatase E1 Methylthioribose-1-phosphate isomerase Methylthioribulose-1-phosphate dehydratase S-methyl-5'-thioadenosine phosphorylase	P17174 Q13126 Q96GX9 Q9BV20 Q9BV57 Q9UHY7	ADI1 APIP ENOPH1 GOT1 MASA MRDI MRI1 MSAP MTAP MTCBP1	Homo sapiens (human)
Enhanced cleavage of VWF variant by ADAMTS13	A disintegrin and metalloproteinase with thrombospondin motifs 13 von Willebrand factor	P04275 Q76LX8	ADAMTS13 C9orf8 F8VWF VWF	Homo sapiens (human)
RHOBTB2 GTPase cycle	Actin, cytoplasmic 2 Alpha-actinin-1 Cullin-3 Drebrin Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Heterogeneous nuclear ribonucleoproteins C1/C2 Hsp90 co-chaperone Cdc37 PH-interacting protein RNA-binding motif protein, X chromosome RNA-binding protein Musashi homolog 2 Rho-related BTB domain-containing protein 2 Serine/arginine repetitive matrix protein 1 Serine/threonine-protein kinase 38 Spliceosome RNA helicase DDX39B T-complex protein 1 subunit beta T-complex protein 1 subunit eta T-complex protein 1 subunit zeta Thioredoxin-like protein 1 Transformer-2 protein homolog beta Tropomodulin-3 Twinfilin-1 Unconventional myosin-VI	O43396 P07900 P07910 P08238 P12814 P38159 P40227 P62995 P63261 P78371 Q12792 Q13618 Q13838 Q15208 Q16543 Q16643 Q8IYB3 Q8WWQ0 Q96DH6 Q99832 Q9BYZ6 Q9NYL9 Q9UM54	99D8.1 ACTG ACTG1 ACTN1 BAT1 CCT2 CCT6 CCT6A CCT7 CCTB CCTH CCTZ CDC37 CDC37A CUL3 D0S117E DBC2 DBN1 DCAF14 DDX39B HNRNPC HNRPC HNRPG HSP90A HSP90AA1 HSP90AB1 HSP90B HSPC1 HSPC2 HSPC3 HSPCA HSPCB KIAA0389 KIAA0617 KIAA0717 MSI2 MYO6 NDR1 NIP7-1 PHIP PTK9 RBMX RBMXP1 RHOBTB2 SFRS10 SRM160 SRRM1 STK38 TMOD3 TRA2B TRP32 TWF1 TXL TXNL TXNL1 UAP56 WDR11	Homo sapiens (human)
RHOC GTPase cycle	A-kinase anchor protein 13 ATP-binding cassette sub-family D member 3 Active breakpoint cluster region-related protein Acyl-CoA-binding domain-containing protein 5 Anillin Breakpoint cluster region protein Caveolae-associated protein 1 Caveolin-1 Cell surface glycoprotein MUC18 Citron Rho-interacting kinase Coiled-coil domain-containing protein 187 Complement component 1 Q subcomponent-binding protein, mitochondrial DEP domain-containing protein 1B Delta(14)-sterol reductase LBR Disheveled-associated activator of morphogenesis 1 Erbin Flotillin-1 Flotillin-2 Formin-like protein 2 Formin-like protein 3 Guanine nucleotide exchange factor DBS Guanine nucleotide exchange factor VAV2 Junction plakoglobin Lamina-associated polypeptide 2, isoforms beta/gamma Macoilin Oligophrenin-1 Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein Phosphatidylinositol 3-kinase regulatory subunit alpha Protein ERGIC-53 Protein diaphanous homolog 1 Protein diaphanous homolog 3 Proto-oncogene DBL Rac GTPase-activating protein 1 Ras GTPase-activating-like protein IQGAP1 Ras GTPase-activating-like protein IQGAP3 Rho GDP-dissociation inhibitor 1 Rho GTPase-activating protein 18 Rho GTPase-activating protein 1 Rho GTPase-activating protein 21 Rho GTPase-activating protein 26 Rho GTPase-activating protein 32 Rho GTPase-activating protein 35 Rho GTPase-activating protein 39 Rho GTPase-activating protein 5 Rho GTPase-activating protein 7 Rho guanine nucleotide exchange factor 10-like protein Rho guanine nucleotide exchange factor 10 Rho guanine nucleotide exchange factor 11 Rho guanine nucleotide exchange factor 12 Rho guanine nucleotide exchange factor 17 Rho guanine nucleotide exchange factor 1 Rho guanine nucleotide exchange factor 25 Rho guanine nucleotide exchange factor 28 Rho guanine nucleotide exchange factor 40 Rho guanine nucleotide exchange factor 5 Rho-associated protein kinase 1 Rho-associated protein kinase 2 Rho-related GTP-binding protein RhoC Rhotekin STE20-like serine/threonine-protein kinase Serine/threonine-protein kinase 10 Serine/threonine-protein kinase N1 Serine/threonine-protein kinase N2 Serine/threonine-protein kinase N3 StAR-related lipid transfer protein 13 Stomatin Syntaxin-5 Tight junction protein ZO-2 Transferrin receptor protein 1 Transforming protein RhoA Unconventional myosin-IXb Vang-like protein 1 Vesicle-associated membrane protein 3 Vesicle-associated membrane protein-associated protein B/C	A0A096LP49 A7KAX9 O14578 O15013 O15068 O15085 O60610 O60890 O75116 O75955 O94804 O95292 P02786 P08134 P10911 P11274 P14923 P27105 P27986 P28288 P42167 P43121 P46940 P49257 P52565 P52735 P61586 Q03135 Q07021 Q07960 Q12774 Q12802 Q12979 Q13017 Q13190 Q13459 Q13464 Q14254 Q14739 Q15836 Q16512 Q16513 Q5T5U3 Q5T8D3 Q6NZI2 Q6P5Z2 Q86VI3 Q86VW2 Q8IVF7 Q8N1W1 Q8N392 Q8N5G2 Q8TAA9 Q8TCU6 Q8TER5 Q8WUY9 Q92888 Q96PE2 Q96PY5 Q96QB1 Q96RT1 Q9BST9 Q9C0H5 Q9H0H5 Q9H2G2 Q9HCE6 Q9NQW6 Q9NRY4 Q9NSV4 Q9NZN5 Q9UDY2 Q9UNA1 Q9Y3M8 Q9Y4D1	ABCD3 ABR ACBD5 AKAP13 ANLN ARH12 ARH9 ARHA ARHC ARHGAP1 ARHGAP10 ARHGAP18 ARHGAP21 ARHGAP26 ARHGAP32 ARHGAP35 ARHGAP39 ARHGAP5 ARHGAP7 ARHGDIA ARHGEF1 ARHGEF10 ARHGEF10L ARHGEF11 ARHGEF12 ARHGEF17 ARHGEF25 ARHGEF28 ARHGEF40 ARHGEF5 BCR BCR1 BND7 BRX C1QBP CAV CAV1 CAVIN1 CCDC187 CDC42GAP CIT CRIK CTNNG D22S11 DAAM1 DBL DEPDC1B DIAP1 DIAP3 DIAPH1 DIAPH3 DLC1 DLC2 DP3 EPB72 ERBB2IP ERBIN ERGIC53 ESA1 F5F8D FHOD2 FHOD3 FLOT1 FLOT2 FMNL2 FMNL3 FRL2 GC1QBP GDIA1 GEFT GRAF GRB1 GRF1 GRINCHGEF GRIT GRLF1 GT650 HABP1 HT31 IQGAP1 IQGAP3 JUP KIAA0051 KIAA0204 KIAA0294 KIAA0337 KIAA0362 KIAA0380 KIAA0382 KIAA0619 KIAA0621 KIAA0666 KIAA0712 KIAA0949 KIAA1225 KIAA1415 KIAA1424 KIAA1478 KIAA1626 KIAA1688 KIAA1722 KIAA1723 KIAA1902 KIAA1996 KIAA1998 KIAA2014 LAP2 LARG LBC LBR LMAN1 LOK M17S1 MACO1 MCAM MCF2 MCF2L MGCRACGAP MUC18 MYO9B MYR5 OPHN1 OPHN1L OST P190A PAK1 PIK3R1 PKN PKN1 PKN2 PKN3 PKNBETA PMP70 PREX1 PRK1 PRK2 PRKCL1 PRKCL2 PTRF PXMP1 RACGAP1 RGNEF RHO12 RHOA RHOC RHOGAP1 RHOGAP5 RICS ROCK1 ROCK2 RTKN RTKN1 SF2P32 SLK SOLO STARD12 STARD13 STB2 STK10 STK2 STK21 STOM STX5 STX5A SYB3 TEM4 TFRC TIM TJP2 TMEM57 TMPO VAMP3 VANGL1 VAPB VAV2 WBP3 X104 XTP8 ZO2 p190ARHOGAP	Homo sapiens (human)
Chylomicron clearance	Apolipoprotein B-100 Apolipoprotein E Hepatic triacylglycerol lipase Low density lipoprotein receptor adapter protein 1 Low-density lipoprotein receptor	P01130 P02649 P04114 P11150 Q5SW96	APOB APOE ARH HTGL LDLR LDLRAP1 LIPC	Homo sapiens (human)
Sensory processing of sound by inner hair cells of the cochlea	Band 4.1-like protein 1 Band 4.1-like protein 3 Cadherin-23 Calcium and integrin-binding family member 2 Calcium-activated potassium channel subunit alpha-1 Calcium-activated potassium channel subunit beta-1 Calcium-binding protein 1 Calcium-binding protein 2 Chloride intracellular channel protein 5 DnaJ homolog subfamily C member 5 Epidermal growth factor receptor kinase substrate 8-like protein 2 Epidermal growth factor receptor kinase substrate 8 Espin-like protein Espin Ezrin F-actin-capping protein subunit alpha-1 F-actin-capping protein subunit alpha-2 F-actin-capping protein subunit beta Fascin-2 Glutaredoxin domain-containing cysteine-rich protein 1 Glutaredoxin domain-containing cysteine-rich protein 2 Harmonin LHFPL tetraspan subfamily member 5 protein Leucine-rich repeat-containing protein 52 Moesin Myosin-9 Myosin-IIIa Myosin-IIIb Otoferlin Pejvakin Peripheral plasma membrane protein CASK Plasma membrane calcium-transporting ATPase 1 Plastin-1 Potassium voltage-gated channel subfamily KQT member 4 Protein bassoon Protein piccolo Protocadherin-15 Radixin Ras-related protein Rab-3A Rho family-interacting cell polarization regulator 2 Spectrin alpha chain, non-erythrocytic 1 Spectrin beta chain, non-erythrocytic 1 Stereocilin Synapsin-1 Synaptophysin Synaptosomal-associated protein 25 Syntaxin-1A Taperin Transmembrane channel-like protein 1 Transmembrane channel-like protein 2 Transmembrane inner ear expressed protein Twinfilin-1 Twinfilin-2 Unconventional myosin-Ic Unconventional myosin-VIIa Unconventional myosin-XV Vesicle-associated membrane protein 2 Vesicular glutamate transporter 3 Voltage-dependent L-type calcium channel subunit alpha-1D Voltage-dependent L-type calcium channel subunit beta-2 Voltage-dependent calcium channel subunit alpha-2/delta-2 Whirlin Xin actin-binding repeat-containing protein 2 pre-mRNA splicing regulator USH1G	A4UGR9 A6NFK2 A8MXD5 B1AK53 O00159 O14926 O14936 O75838 P08247 P15311 P17600 P20020 P20336 P26038 P35241 P35579 P47755 P47756 P52907 P56696 P60880 P63027 Q01082 Q01668 Q08289 Q0ZLH3 Q12791 Q12792 Q12929 Q13402 Q13813 Q14651 Q16558 Q16623 Q495M9 Q4KMQ1 Q6IBS0 Q6ZVH7 Q7RTU9 Q8N7C0 Q8NDX2 Q8NEV4 Q8NEW7 Q8TAF8 Q8TDI7 Q8TDI8 Q8WXR4 Q96QU1 Q9H251 Q9H3Z4 Q9H4G0 Q9H6S3 Q9HC10 Q9NPB3 Q9NY47 Q9NZA1 Q9NZU7 Q9P202 Q9UKN7 Q9UPA5 Q9Y2J2 Q9Y4F9 Q9Y6N9 Q9Y6V0	ACZ AIE75 ATP2B1 BSN C20orf145 C6orf32 C9orf75 CABP1 CABP2 CACH3 CACN4 CACNA1D CACNA2D2 CACNB2 CACNL1A2 CACNLB2 CAPZA1 CAPZA2 CAPZB CASK CCHL1A2 CDH23 CIB2 CLIC5 CLN4 CMYA3 DAL1 DFNB25 DFNB31 DFNB36 DFNB59 DIFF48 DNAJC5 EPB41L1 EPB41L3 EPS8 EPS8L2 EPS8R2 ESPN ESPNL EZR FAM65B FER1L2 FSCN2 GRXCR1 GRXCR2 KCNMA KCNMA1 KCNMB1 KCNQ4 KIAA0338 KIAA0386 KIAA0434 KIAA0558 KIAA0559 KIAA0987 KIAA1526 KIAA1774 KIAA1812 KIP2 LHFPL5 LIN2 LRRC52 MSN MYH9 MYO15 MYO15A MYO1C MYO3A MYO3B MYO7A MYSB NEAS OTOF PCDH15 PCLO PJVK PL48 PLS1 PMCA1 PTK9 PTK9L RAB3A RDX RIPOR2 SANS SLC17A8 SLO SNAP SNAP25 SPTA2 SPTAN1 SPTB2 SPTBN1 STRC STX1 STX1A SYB2 SYN1 SYP TMC1 TMC2 TMHS TMIE TPRN TWF1 TWF2 USH1B USH1C USH1F USH1G VAMP2 VGLUT3 VIL2 WHRN XIRP2 ZNF231	Homo sapiens (human)
Activation of RAC1 downstream of NMDARs	ARF GTPase-activating protein GIT1 Calcium/calmodulin-dependent protein kinase kinase 1 Calcium/calmodulin-dependent protein kinase kinase 2 Calcium/calmodulin-dependent protein kinase type 1 Calmodulin-1 Ras-related C3 botulinum toxin substrate 1	P0DP23 P63000 Q14012 Q8N5S9 Q96RR4 Q9Y2X7	CALM CALM1 CAM CAM1 CAMK1 CAMKK1 CAMKK2 CAMKKA CAMKKB GIT1 KIAA0787 RAC1 TC25	Homo sapiens (human)
Urea cycle	Arginase-1 Arginase-2, mitochondrial Argininosuccinate lyase Argininosuccinate synthase Carbamoyl-phosphate synthase [ammonia], mitochondrial Mitochondrial ornithine transporter 1 Mitochondrial ornithine transporter 2 N-acetylglutamate synthase, mitochondrial NmrA-like family domain-containing protein 1 Ornithine transcarbamylase, mitochondrial	P00480 P00966 P04424 P05089 P31327 P78540 Q8N159 Q9BXI2 Q9HBL8 Q9Y619	ARG1 ARG2 ASL ASS ASS1 CPS1 HSCARG NAGS NMRAL1 ORC1 ORC2 ORNT1 ORNT2 OTC SLC25A15 SLC25A2	Homo sapiens (human)
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks	Amyloid beta precursor protein binding family B member 1 BRCA1-A complex subunit Abraxas 1 BRCA1-A complex subunit RAP80 BRCA1-associated RING domain protein 1 BRISC and BRCA1-A complex member 1 BRISC and BRCA1-A complex member 2 Breast cancer type 1 susceptibility protein Cellular tumor antigen p53 DNA repair protein RAD50 Double-strand break repair protein MRE11 E3 SUMO-protein ligase PIAS4 E3 ubiquitin-protein ligase HERC2 E3 ubiquitin-protein ligase RNF168 E3 ubiquitin-protein ligase RNF8 Eyes absent homolog 1 Eyes absent homolog 2 Eyes absent homolog 3 Eyes absent homolog 4 Histone H2AX Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/F/G/I Histone H2B type 1-D Histone H2B type 1-H Histone H2B type 1-J Histone H2B type 1-K Histone H2B type 1-L Histone H2B type 1-M Histone H2B type 1-N Histone H2B type 1-O Histone H2B type 2-E Histone H2B type 3-B Histone H2B type F-S Histone H3.1t Histone H4 Histone acetyltransferase KAT5 Histone-lysine N-methyltransferase NSD2 Lys-63-specific deubiquitinase BRCC36 Lysine-specific demethylase 4A Lysine-specific demethylase 4B Mediator of DNA damage checkpoint protein 1 Mitogen-activated protein kinase 8 Nibrin Polyubiquitin-B Polyubiquitin-C SUMO-conjugating enzyme UBC9 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 Serine-protein kinase ATM Serine/threonine-protein kinase Chk2 Serine/threonine-protein phosphatase 5 Small ubiquitin-related modifier 1 TP53-binding protein 1 Tyrosine-protein kinase ABL1 Tyrosine-protein kinase BAZ1B UBX domain-containing protein 1 Ubiquitin carboxyl-terminal hydrolase BAP1 Ubiquitin-conjugating enzyme E2 N Ubiquitin-conjugating enzyme E2 variant 2 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00167 O00213 O60264 O60814 O60934 O75164 O76064 O94953 O95677 O95714 O96017 O96028 P00519 P04637 P06899 P0CG47 P0CG48 P16104 P23527 P33778 P38398 P45983 P46736 P49959 P53041 P57053 P58876 P61088 P62805 P62807 P62979 P62987 P63165 P63279 Q04323 Q12888 Q13315 Q14676 Q15819 Q16695 Q16778 Q6UWZ7 Q8IYW5 Q8N257 Q8N2W9 Q92560 Q92878 Q92993 Q93079 Q96A08 Q96RL1 Q99502 Q99504 Q99728 Q99877 Q99879 Q99880 Q9NWV8 Q9NXR7 Q9UIG0	ABL ABL1 ABRA1 ABRAXAS1 APBB1 ATM BABAM1 BABAM2 BAP1 BARD1 BAZ1B BLU BRCA1 BRCC3 BRCC36 BRCC45 BRE C19orf62 C6.1A CCDC98 CDS1 CHEK2 CHK2 CXorf53 EAB1 EYA1 EYA2 EYA3 EYA4 FAM175A FE65 H2AFX H2AX H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H2BFA H2BFB H2BFC H2BFD H2BFE H2BFF H2BFG H2BFH H2BFJ H2BFK H2BFL H2BFN H2BFQ H2BFR H2BFS H2BFT H2BS1 H2BU1 H3-4 H3FT H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HERC2 HIRIP1 HIRIP2 HIST1H2BA HIST1H2BB HIST1H2BC HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2BI HIST1H2BJ HIST1H2BK HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H2BE HIST2H4 HIST2H4A HIST2H4B HIST3H2BB HIST3H3 HIST4H4 HNGS1 HTATIP JHDM3A JHDM3B JMJD2 JMJD2A JMJD2B JNK1 JTK7 KAT5 KDM4A KDM4B KIAA0170 KIAA0272 KIAA0646 KIAA0677 KIAA0876 KIAA1090 MAPK8 MDC1 MERIT40 MMS2 MMSET MRE11 MRE11A NBA1 NBN NBS NBS1 NFBD1 NSD2 P53 P95 PIAS4 PIASG PPP5 PPP5C PRKM8 RAD50 RAD53 RAP80 RIR RNF168 RNF53 RNF8 RPS27A RXRIP110 SAKS1 SAPK1 SAPK1C SMARCA5 SMT3C SMT3H3 SNF2H SUMO1 TIP60 TP53 TP53BP1 TRX5 TSH2B UBA52 UBA80 UBB UBC UBC9 UBCE9 UBCEP1 UBCEP2 UBE2I UBE2N UBE2V2 UBL1 UBXN1 UEV2 UIMC1 WBSC10 WBSCR10 WBSCR9 WCRF135 WHSC1 WSTF	Homo sapiens (human)
Synthesis And Processing Of GAG, GAGPOL Polyproteins	Gag polyprotein	P04591	gag	Homo sapiens (human)
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors	Apolipoprotein E Protein DEK Transcription factor AP-2-alpha	P02649 P05549 P35659	AP2TF APOE DEK TFAP2 TFAP2A	Homo sapiens (human)
Defective SLC17A8 causes autosomal dominant deafness 25 (DFNA25)	Vesicular glutamate transporter 3	Q8NDX2	SLC17A8 VGLUT3	Homo sapiens (human)
Toll Like Receptor TLR6:TLR2 Cascade	Monocyte differentiation antigen CD14 Peptidyl-prolyl cis-trans isomerase Mip Platelet glycoprotein 4 Toll-like receptor 2 Toll-like receptor 6	O60603 P08571 P16671 P26623 Q9Y2C9	CD14 CD36 GP3B GP4 TIL4 TLR2 TLR6 mip	Homo sapiens (human)
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components	Alpha-actinin-1 Alpha-parvin Beta-parvin Dual specificity testis-specific protein kinase 1 LIM and senescent cell antigen-like-containing domain protein 1 Paxillin Ras suppressor protein 1 Rho guanine nucleotide exchange factor 6	P12814 P48059 P49023 Q15052 Q15404 Q15569 Q9HBI1 Q9NVD7	ACTN1 ARHGEF6 COOL2 KIAA0006 LIMS1 MXRA2 PARVA PARVB PINCH PINCH1 PIXA PXN RSP1 RSU1 TESK1	Homo sapiens (human)
SUMOylation of DNA replication proteins	Aladin Aurora kinase A Aurora kinase B Baculoviral IAP repeat-containing protein 5 Borealin DNA topoisomerase 1 DNA topoisomerase 2-alpha DNA topoisomerase 2-beta E3 SUMO-protein ligase PIAS3 E3 SUMO-protein ligase PIAS4 E3 SUMO-protein ligase RanBP2 Inner centromere protein Nuclear envelope pore membrane protein POM 121 Nuclear envelope pore membrane protein POM 121C Nuclear pore complex protein Nup107 Nuclear pore complex protein Nup133 Nuclear pore complex protein Nup153 Nuclear pore complex protein Nup155 Nuclear pore complex protein Nup160 Nuclear pore complex protein Nup205 Nuclear pore complex protein Nup214 Nuclear pore complex protein Nup50 Nuclear pore complex protein Nup85 Nuclear pore complex protein Nup88 Nuclear pore complex protein Nup93 Nuclear pore glycoprotein p62 Nuclear pore membrane glycoprotein 210 Nucleoporin NDC1 Nucleoporin NUP188 Nucleoporin NUP35 Nucleoporin NUP42 Nucleoporin Nup37 Nucleoporin Nup43 Nucleoporin p54 Nucleoprotein TPR Proliferating cell nuclear antigen Protein SEC13 homolog Ran GTPase-activating protein 1 SUMO-conjugating enzyme UBC9 Small ubiquitin-related modifier 1 Small ubiquitin-related modifier 2 Small ubiquitin-related modifier 3 mRNA export factor RAE1	A8CG34 O14965 O15392 O15504 O75694 P11387 P11388 P12004 P12270 P35658 P37198 P46060 P49790 P49792 P55735 P55854 P57740 P61956 P63165 P63279 P78406 Q02880 Q12769 Q53HL2 Q5SRE5 Q7Z3B4 Q8N1F7 Q8N2W9 Q8NFH3 Q8NFH4 Q8NFH5 Q8TEM1 Q8WUM0 Q92621 Q96GD4 Q96HA1 Q99567 Q9BTX1 Q9BW27 Q9NQS7 Q9NRG9 Q9UKX7 Q9Y6X2	AAAS ADRACALA AIK AIK2 AIM1 AIRK1 AIRK2 API4 ARK1 ARK2 AURA AURKA AURKB AYK1 BIRC5 BTAK C7orf14 CAIN CAN CDCA8 CG1 D3S1231E IAK1 IAP4 INCENP KIAA0023 KIAA0095 KIAA0169 KIAA0197 KIAA0225 KIAA0618 KIAA0791 KIAA0906 KIAA1835 MP44 MRNP41 NDC1 NPAP60L NUP107 NUP120 NUP121 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP358 NUP37 NUP42 NUP43 NUP50 NUP53 NUP54 NUP62 NUP75 NUP85 NUP88 NUP93 NUPL2 PCNA PCNT1 PESCRG3 PIAS3 PIAS4 PIASG POM121 POM121A POM121C RAE1 RANBP2 RANGAP1 SD SEC13 SEC13A SEC13L1 SEC13R SMT3A SMT3B SMT3C SMT3H1 SMT3H2 SMT3H3 STK1 STK12 STK15 STK5 STK6 SUMO1 SUMO2 SUMO3 TMEM48 TOP1 TOP2 TOP2A TOP2B TPR UBC9 UBCE9 UBE2I UBL1	Homo sapiens (human)
Cytosolic iron-sulfur cluster assembly	Anamorsin Cytosolic Fe-S cluster assembly factor NUBP1 Cytosolic Fe-S cluster assembly factor NUBP2 Cytosolic iron-sulfur assembly component 2B Cytosolic iron-sulfur assembly component 3 DNA polymerase delta catalytic subunit Fanconi anemia group J protein General transcription and DNA repair factor IIH helicase subunit XPD Iron-sulfur clusters transporter ABCB7, mitochondrial MMS19 nucleotide excision repair protein homolog NADPH-dependent diflavin oxidoreductase 1 Probable cytosolic iron-sulfur protein assembly protein CIAO1 Regulator of telomere elongation helicase 1	O75027 O76071 P18074 P28340 P53384 Q6FI81 Q96T76 Q9BX63 Q9H6Q4 Q9NZ71 Q9UHB4 Q9Y3D0 Q9Y5Y2	ABC7 ABCB7 BACH1 BRIP1 C20orf41 CIA1 CIAB CIAO1 CIAO2B CIAO3 CIAPIN1 ERCC2 FAM96B FANCJ KIAA1088 MIP18 MMS19 MMS19L NARFL NBP NBP1 NDOR1 NHL NR1 NUBP1 NUBP2 POLD POLD1 PRN RTEL1 WDR39 XPD XPDC	Homo sapiens (human)
Defective MGAT2 causes CDG-2a	Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Q10469	MGAT2	Homo sapiens (human)
FLT3 signaling through SRC family kinases	Fms-related tyrosine kinase 3 ligand Receptor-type tyrosine-protein kinase FLT3 Tyrosine-protein kinase Fyn Tyrosine-protein kinase HCK Tyrosine-protein kinase Lck Tyrosine-protein kinase SYK	P06239 P06241 P08631 P36888 P43405 P49771	CD135 FLK2 FLT3 FLT3LG FYN HCK LCK STK1 SYK	Homo sapiens (human)
Proton/oligopeptide cotransporters	Solute carrier family 15 member 1 Solute carrier family 15 member 2 Solute carrier family 15 member 3 Solute carrier family 15 member 4	P46059 Q16348 Q8IY34 Q8N697	OCTP PEPT1 PEPT2 PHT1 PHT2 PTR3 PTR4 SLC15A1 SLC15A2 SLC15A3 SLC15A4	Homo sapiens (human)
Tandem pore domain halothane-inhibited K+ channel (THIK)	Potassium channel subfamily K member 13	Q9HB14	KCNK13	Homo sapiens (human)
Toll Like Receptor 7/8 (TLR7/8) Cascade	Toll-like receptor 7 Toll-like receptor 8	Q9NR97 Q9NYK1	TLR7 TLR8	Homo sapiens (human)
NOTCH2 Activation and Transmission of Signal to the Nucleus	Contactin-1 Delta-like protein 1 Delta-like protein 4 Disintegrin and metalloproteinase domain-containing protein 10 E3 ubiquitin-protein ligase MIB1 E3 ubiquitin-protein ligase MIB2 E3 ubiquitin-protein ligase NEURL1 E3 ubiquitin-protein ligase NEURL1B Gamma-secretase subunit APH-1A Gamma-secretase subunit APH-1B Gamma-secretase subunit PEN-2 Midkine Neurogenic locus notch homolog protein 2 Nicastrin Polyubiquitin-B Polyubiquitin-C Presenilin-1 Presenilin-2 Protein jagged-1 Protein jagged-2 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A8MQ27 O00548 O14672 O76050 P0CG47 P0CG48 P21741 P49768 P49810 P62979 P62987 P78504 Q04721 Q12860 Q86YT6 Q8WW43 Q92542 Q96AX9 Q96BI3 Q9NR61 Q9NZ42 Q9Y219	AD3 AD4 ADAM10 APH1A APH1B CNTN1 DIP1 DLL1 DLL4 JAG1 JAG2 JAGL1 KIAA0253 KIAA1323 KUZ MADM MDK MIB1 MIB2 MK1 NCSTN NEGF2 NEURL NEURL1 NEURL1A NEURL1B NEURL3 NOTCH2 PEN2 PS1 PS2 PSEN1 PSEN2 PSENEN PSF PSFL PSNL1 PSNL2 RNF67 RPS27A SKD STM2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 ZZANK1 ZZANK2	Homo sapiens (human)
Acyl chain remodelling of PC	85/88 kDa calcium-independent phospholipase A2 Calcium-independent phospholipase A2-gamma Cytosolic phospholipase A2 beta Cytosolic phospholipase A2 delta Cytosolic phospholipase A2 epsilon Cytosolic phospholipase A2 gamma Cytosolic phospholipase A2 zeta Cytosolic phospholipase A2 Group 10 secretory phospholipase A2 Group 3 secretory phospholipase A2 Group IID secretory phospholipase A2 Group IIE secretory phospholipase A2 Group IIF secretory phospholipase A2 Group XIIA secretory phospholipase A2 Lysophosphatidylcholine acyltransferase 1 Lysophosphatidylcholine acyltransferase 2 Lysophospholipid acyltransferase 2 Lysophospholipid acyltransferase 5 Lysophospholipid acyltransferase LPCAT4 Lysoplasmalogenase TMEM86B Phospholipase A and acyltransferase 3 Phospholipase A2 group V Phospholipase A2, membrane associated Phospholipase A2 Phospholipase B-like 1 Phospholipase B1, membrane-associated Secretory phospholipase A2 receptor	O15496 O60733 P04054 P0C869 P14555 P39877 P47712 P53816 Q13018 Q3MJ16 Q643R3 Q68DD2 Q6P1A2 Q6P1J6 Q6P4A8 Q6ZWT7 Q7L5N7 Q86XP0 Q8N661 Q8NF37 Q9BZM1 Q9BZM2 Q9NP80 Q9NZ20 Q9NZK7 Q9UNK4 Q9UP65	AGPAT11 AGPAT7 AYTL1 AYTL2 AYTL3 CLEC13C CPLA2 HRASLS3 HREV107 IPLA22 IPLA2G LPCAT1 LPCAT2 LPCAT3 LPCAT4 LPEAT2 MBOAT2 MBOAT5 OACT2 OACT5 PFAAP3 PLA2 PLA2A PLA2B PLA2G10 PLA2G12 PLA2G12A PLA2G16 PLA2G1B PLA2G2A PLA2G2D PLA2G2E PLA2G2F PLA2G3 PLA2G4 PLA2G4A PLA2G4B PLA2G4C PLA2G4D PLA2G4E PLA2G4F PLA2G5 PLA2G6 PLA2L PLA2R1 PLAAT3 PLB PLB1 PLBD1 PLPLA9 PNPLA8 PPLA2 RASF-A SPLASH TMEM86B	Homo sapiens (human)
FasL/ CD95L signaling	Caspase-10 Caspase-8 FAS-associated death domain protein Tumor necrosis factor ligand superfamily member 6 Tumor necrosis factor receptor superfamily member 6	P25445 P48023 Q13158 Q14790 Q92851	APT1 APT1LG1 CASP10 CASP8 CD95L FADD FAS FAS1 FASL FASLG MCH4 MCH5 MORT1 TNFRSF6 TNFSF6	Homo sapiens (human)

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