GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **201 - 225** of **2090** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▲	Organism
Class I peroxisomal membrane protein import	ATP-binding cassette sub-family D member 1 ATP-binding cassette sub-family D member 2 ATP-binding cassette sub-family D member 3 Acyl-CoA-binding domain-containing protein 5 Ganglioside-induced differentiation-associated protein 1 Mitochondrial fission 1 protein Outer mitochondrial transmembrane helix translocase Peroxisomal biogenesis factor 19 Peroxisomal biogenesis factor 3 Peroxisomal membrane protein 11B Peroxisomal membrane protein 2 Peroxisomal membrane protein 4 Peroxisomal membrane protein PEX13 Peroxisomal membrane protein PEX14 Peroxisomal membrane protein PEX16 Peroxisomal membrane protein PMP34 Peroxisome assembly protein 12 Peroxisome assembly protein 26 Peroxisome biogenesis factor 2	O00623 O43808 O75381 O96011 P28288 P28328 P33897 P40855 P56589 Q5T8D3 Q7Z412 Q8NBU5 Q8TB36 Q92968 Q9NR77 Q9UBJ2 Q9Y3D6 Q9Y5Y5 Q9Y6I8	ABCD1 ABCD2 ABCD3 ACBD5 ALD ALD1 ALDL1 ALDR ALDRP ATAD1 FIS1 GDAP1 HK33 KIAA1996 PAF1 PAF3 PEX11B PEX12 PEX13 PEX14 PEX16 PEX19 PEX2 PEX26 PEX3 PMP22 PMP24 PMP3 PMP34 PMP35 PMP70 PXF PXMP1 PXMP2 PXMP3 PXMP4 RNF72 SLC25A17 TTC11	Homo sapiens (human)
Beta-oxidation of very long chain fatty acids	3-ketoacyl-CoA thiolase, peroxisomal ATP-binding cassette sub-family D member 1 Acyl-coenzyme A thioesterase 6 Acyl-coenzyme A thioesterase 8 Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing] Peroxisomal bifunctional enzyme Peroxisomal multifunctional enzyme type 2 Peroxisomal succinyl-coenzyme A thioesterase	O14734 P09110 P33897 P51659 Q08426 Q3I5F7 Q8N9L9 Q9NUI1	ABCD1 ACAA ACAA1 ACOT4 ACOT6 ACOT8 ACTEIII ALD C14orf42 DECR2 ECHD EDH17B4 EHHADH HSD17B4 PDCR PTE1 PTE2B PTEIB PTHIO SDR17C1 SDR8C1	Homo sapiens (human)
alpha-linolenic acid (ALA) metabolism	3-ketoacyl-CoA thiolase, peroxisomal ATP-binding cassette sub-family D member 1 Acyl-CoA (8-3)-desaturase Acyl-CoA 6-desaturase Acyl-coenzyme A thioesterase 8 Long-chain-fatty-acid--CoA ligase 1 Peroxisomal multifunctional enzyme type 2 Sterol carrier protein 2 Very long chain fatty acid elongase 1 Very long chain fatty acid elongase 2 Very long chain fatty acid elongase 3 Very long chain fatty acid elongase 5	O14734 O60427 O95864 P09110 P22307 P33121 P33897 P51659 Q9BW60 Q9HB03 Q9NXB9 Q9NYP7	ABCD1 ACAA ACAA1 ACOT8 ACSL1 ACTEIII ALD CIG30 EDH17B4 ELG3 ELOVL1 ELOVL2 ELOVL3 ELOVL5 FACL1 FACL2 FADS1 FADS2 FADSD5 HSD17B4 LACS LACS1 LACS2 PTE1 PTHIO SCP2 SDR8C1 SSC1 SSC2	Homo sapiens (human)
Linoleic acid (LA) metabolism	ATP-binding cassette sub-family D member 1 Acyl-CoA (8-3)-desaturase Acyl-CoA 6-desaturase Long-chain-fatty-acid--CoA ligase 1 Very long chain fatty acid elongase 1 Very long chain fatty acid elongase 2 Very long chain fatty acid elongase 3 Very long chain fatty acid elongase 5	O60427 O95864 P33121 P33897 Q9BW60 Q9HB03 Q9NXB9 Q9NYP7	ABCD1 ACSL1 ALD CIG30 ELG3 ELOVL1 ELOVL2 ELOVL3 ELOVL5 FACL1 FACL2 FADS1 FADS2 FADSD5 LACS LACS1 LACS2 SSC1 SSC2	Homo sapiens (human)
Defective ABCD1 causes ALD	ATP-binding cassette sub-family D member 1	P33897	ABCD1 ALD	Homo sapiens (human)
RHOC GTPase cycle	A-kinase anchor protein 13 ATP-binding cassette sub-family D member 3 Active breakpoint cluster region-related protein Acyl-CoA-binding domain-containing protein 5 Anillin Breakpoint cluster region protein Caveolae-associated protein 1 Caveolin-1 Cell surface glycoprotein MUC18 Citron Rho-interacting kinase Coiled-coil domain-containing protein 187 Complement component 1 Q subcomponent-binding protein, mitochondrial DEP domain-containing protein 1B Delta(14)-sterol reductase LBR Disheveled-associated activator of morphogenesis 1 Erbin Flotillin-1 Flotillin-2 Formin-like protein 2 Formin-like protein 3 Guanine nucleotide exchange factor DBS Guanine nucleotide exchange factor VAV2 Junction plakoglobin Lamina-associated polypeptide 2, isoforms beta/gamma Macoilin Oligophrenin-1 Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein Phosphatidylinositol 3-kinase regulatory subunit alpha Protein ERGIC-53 Protein diaphanous homolog 1 Protein diaphanous homolog 3 Proto-oncogene DBL Rac GTPase-activating protein 1 Ras GTPase-activating-like protein IQGAP1 Ras GTPase-activating-like protein IQGAP3 Rho GDP-dissociation inhibitor 1 Rho GTPase-activating protein 18 Rho GTPase-activating protein 1 Rho GTPase-activating protein 21 Rho GTPase-activating protein 26 Rho GTPase-activating protein 32 Rho GTPase-activating protein 35 Rho GTPase-activating protein 39 Rho GTPase-activating protein 5 Rho GTPase-activating protein 7 Rho guanine nucleotide exchange factor 10-like protein Rho guanine nucleotide exchange factor 10 Rho guanine nucleotide exchange factor 11 Rho guanine nucleotide exchange factor 12 Rho guanine nucleotide exchange factor 17 Rho guanine nucleotide exchange factor 1 Rho guanine nucleotide exchange factor 25 Rho guanine nucleotide exchange factor 28 Rho guanine nucleotide exchange factor 40 Rho guanine nucleotide exchange factor 5 Rho-associated protein kinase 1 Rho-associated protein kinase 2 Rho-related GTP-binding protein RhoC Rhotekin STE20-like serine/threonine-protein kinase Serine/threonine-protein kinase 10 Serine/threonine-protein kinase N1 Serine/threonine-protein kinase N2 Serine/threonine-protein kinase N3 StAR-related lipid transfer protein 13 Stomatin Syntaxin-5 Tight junction protein ZO-2 Transferrin receptor protein 1 Transforming protein RhoA Unconventional myosin-IXb Vang-like protein 1 Vesicle-associated membrane protein 3 Vesicle-associated membrane protein-associated protein B/C	A0A096LP49 A7KAX9 O14578 O15013 O15068 O15085 O60610 O60890 O75116 O75955 O94804 O95292 P02786 P08134 P10911 P11274 P14923 P27105 P27986 P28288 P42167 P43121 P46940 P49257 P52565 P52735 P61586 Q03135 Q07021 Q07960 Q12774 Q12802 Q12979 Q13017 Q13190 Q13459 Q13464 Q14254 Q14739 Q15836 Q16512 Q16513 Q5T5U3 Q5T8D3 Q6NZI2 Q6P5Z2 Q86VI3 Q86VW2 Q8IVF7 Q8N1W1 Q8N392 Q8N5G2 Q8TAA9 Q8TCU6 Q8TER5 Q8WUY9 Q92888 Q96PE2 Q96PY5 Q96QB1 Q96RT1 Q9BST9 Q9C0H5 Q9H0H5 Q9H2G2 Q9HCE6 Q9NQW6 Q9NRY4 Q9NSV4 Q9NZN5 Q9UDY2 Q9UNA1 Q9Y3M8 Q9Y4D1	ABCD3 ABR ACBD5 AKAP13 ANLN ARH12 ARH9 ARHA ARHC ARHGAP1 ARHGAP10 ARHGAP18 ARHGAP21 ARHGAP26 ARHGAP32 ARHGAP35 ARHGAP39 ARHGAP5 ARHGAP7 ARHGDIA ARHGEF1 ARHGEF10 ARHGEF10L ARHGEF11 ARHGEF12 ARHGEF17 ARHGEF25 ARHGEF28 ARHGEF40 ARHGEF5 BCR BCR1 BND7 BRX C1QBP CAV CAV1 CAVIN1 CCDC187 CDC42GAP CIT CRIK CTNNG D22S11 DAAM1 DBL DEPDC1B DIAP1 DIAP3 DIAPH1 DIAPH3 DLC1 DLC2 DP3 EPB72 ERBB2IP ERBIN ERGIC53 ESA1 F5F8D FHOD2 FHOD3 FLOT1 FLOT2 FMNL2 FMNL3 FRL2 GC1QBP GDIA1 GEFT GRAF GRB1 GRF1 GRINCHGEF GRIT GRLF1 GT650 HABP1 HT31 IQGAP1 IQGAP3 JUP KIAA0051 KIAA0204 KIAA0294 KIAA0337 KIAA0362 KIAA0380 KIAA0382 KIAA0619 KIAA0621 KIAA0666 KIAA0712 KIAA0949 KIAA1225 KIAA1415 KIAA1424 KIAA1478 KIAA1626 KIAA1688 KIAA1722 KIAA1723 KIAA1902 KIAA1996 KIAA1998 KIAA2014 LAP2 LARG LBC LBR LMAN1 LOK M17S1 MACO1 MCAM MCF2 MCF2L MGCRACGAP MUC18 MYO9B MYR5 OPHN1 OPHN1L OST P190A PAK1 PIK3R1 PKN PKN1 PKN2 PKN3 PKNBETA PMP70 PREX1 PRK1 PRK2 PRKCL1 PRKCL2 PTRF PXMP1 RACGAP1 RGNEF RHO12 RHOA RHOC RHOGAP1 RHOGAP5 RICS ROCK1 ROCK2 RTKN RTKN1 SF2P32 SLK SOLO STARD12 STARD13 STB2 STK10 STK2 STK21 STOM STX5 STX5A SYB3 TEM4 TFRC TIM TJP2 TMEM57 TMPO VAMP3 VANGL1 VAPB VAV2 WBP3 X104 XTP8 ZO2 p190ARHOGAP	Homo sapiens (human)
Uptake of dietary cobalamins into enterocytes	Chymotrypsinogen B2 Chymotrypsinogen B Cobalamin binding intrinsic factor Cubilin Lysosomal cobalamin transport escort protein LMBD1 Lysosomal cobalamin transporter ABCD4 Protein amnionless Serine protease 1 Transcobalamin-1 Trypsin-3	O14678 O60494 P07477 P17538 P20061 P27352 P35030 Q6GPI1 Q9BXJ7 Q9NUN5	ABCD4 AMN C6orf209 CBLIF CTRB CTRB1 CTRB2 CUBN GIF IFCR IFMH LMBRD1 NESI PRSS1 PRSS3 PRSS4 PXMP1L TC1 TCN1 TRP1 TRY1 TRY3 TRY4 TRYP1	Homo sapiens (human)
Defective ABCD4 causes MAHCJ	Lysosomal cobalamin transport escort protein LMBD1 Lysosomal cobalamin transporter ABCD4	O14678 Q9NUN5	ABCD4 C6orf209 LMBRD1 NESI PXMP1L	Homo sapiens (human)
Interferon alpha/beta signaling	2'-5'-oligoadenylate synthase 1 2'-5'-oligoadenylate synthase 2 2'-5'-oligoadenylate synthase 3 2'-5'-oligoadenylate synthase-like protein 2-5A-dependent ribonuclease ATP-binding cassette sub-family E member 1 Bone marrow stromal antigen 2 Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 Double-stranded RNA-specific adenosine deaminase Early growth response protein 1 Guanylate-binding protein 2 HLA class I histocompatibility antigen, A alpha chain HLA class I histocompatibility antigen, B alpha chain HLA class I histocompatibility antigen, C alpha chain HLA class I histocompatibility antigen, alpha chain E HLA class I histocompatibility antigen, alpha chain F HLA class I histocompatibility antigen, alpha chain G Importin subunit alpha-5 Importin subunit beta-1 Inositol hexakisphosphate kinase 2 Interferon alpha-1/13 Interferon alpha-10 Interferon alpha-14 Interferon alpha-16 Interferon alpha-17 Interferon alpha-21 Interferon alpha-2 Interferon alpha-4 Interferon alpha-5 Interferon alpha-6 Interferon alpha-7 Interferon alpha-8 Interferon alpha-inducible protein 27, mitochondrial Interferon alpha-inducible protein 6 Interferon alpha/beta receptor 1 Interferon beta Interferon regulatory factor 1 Interferon regulatory factor 2 Interferon regulatory factor 3 Interferon regulatory factor 4 Interferon regulatory factor 5 Interferon regulatory factor 6 Interferon regulatory factor 7 Interferon regulatory factor 8 Interferon regulatory factor 9 Interferon-induced 35 kDa protein Interferon-induced GTP-binding protein Mx1 Interferon-induced GTP-binding protein Mx2 Interferon-induced protein with tetratricopeptide repeats 1 Interferon-induced protein with tetratricopeptide repeats 2 Interferon-induced protein with tetratricopeptide repeats 3 Interferon-induced protein with tetratricopeptide repeats 5 Interferon-induced transmembrane protein 1 Interferon-induced transmembrane protein 2 Interferon-induced transmembrane protein 3 Interferon-induced, double-stranded RNA-activated protein kinase Interferon-stimulated gene 20 kDa protein Non-receptor tyrosine-protein kinase TYK2 Nucleoprotein Polyubiquitin-B Polyubiquitin-C Proteasome subunit beta type-8 Putative HLA class I histocompatibility antigen, alpha chain H S-adenosylmethionine-dependent nucleotide dehydratase RSAD2 Signal transducer and activator of transcription 1-alpha/beta Signal transducer and activator of transcription 2 Suppressor of cytokine signaling 1 Suppressor of cytokine signaling 3 Tyrosine-protein kinase JAK1 Tyrosine-protein phosphatase non-receptor type 11 Tyrosine-protein phosphatase non-receptor type 6 Ubiquitin-like protein ISG15 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein XIAP-associated factor 1	O14543 O14879 O14896 O15524 P00973 P01562 P01563 P01566 P01567 P01568 P01569 P01570 P01571 P01574 P01889 P01893 P04439 P05013 P05014 P05015 P05161 P09912 P09913 P09914 P0CG47 P0CG48 P0DTC9 P10321 P10914 P13164 P13747 P14316 P17181 P17693 P18146 P19525 P20591 P20592 P23458 P28062 P29350 P29597 P29728 P30511 P32456 P32881 P40305 P42224 P52294 P52630 P55265 P61221 P62979 P62987 P80217 Q00978 Q01628 Q01629 Q02556 Q05823 Q06124 Q10589 Q13325 Q13568 Q14653 Q14974 Q15306 Q15646 Q6GPH4 Q8WXG1 Q92985 Q96AZ6 Q9UHH9 Q9Y3Z3 Q9Y6K5	ABCE1 ADAR ADAR1 BIRC4BP BST2 CD225 CIG-42 CIG-49 CIG5 CIS3 DSRAD EGR1 EIF2AK2 G10P1 G10P2 G1P1 G1P2 G1P3 GBP2 HCP HEM45 HLA-5.4 HLA-6.0 HLA-6.2 HLA-A HLA-B HLA-C HLA-E HLA-F HLA-G HLA-H HLAA HLAB HLAC HLAE HLAF HLAG HLAH ICSBP1 IFB IFI17 IFI27 IFI35 IFI4 IFI54 IFI56 IFI6 IFI60 IFIT1 IFIT2 IFIT3 IFIT4 IFIT5 IFITM1 IFITM2 IFITM3 IFNA1 IFNA10 IFNA13 IFNA14 IFNA16 IFNA17 IFNA2 IFNA21 IFNA2A IFNA2B IFNA2C IFNA4 IFNA5 IFNA6 IFNA7 IFNA8 IFNAI1 IFNAR IFNAR1 IFNB IFNB1 IFP35 IHPK2 IP6K2 IRF1 IRF2 IRF3 IRF4 IRF5 IRF6 IRF7 IRF8 IRF9 ISG15 ISG20 ISG54 ISG56 ISG58 ISG60 ISGF3G JAK1 JAK1A JAK1B KPNA1 KPNB1 KROX24 LMP7 MOP5 MUM1 MX1 MX2 N NTF97 OAS1 OAS2 OAS3 OASL OIAS PKR PRKR PSMB5i PSMB8 PTP1C PTP2C PTPN11 PTPN6 RCH2 RI58 RING10 RLI RNASEL RNASEL1 RNASELI RNS4 RNS4I RPS27A RSAD2 SAMHD1 SHPTP2 SOCS1 SOCS3 SSI1 SSI3 STAT1 STAT2 TIP3 TRIP14 TYK2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 UCRP XAF1 XIAPAF1 Y2 ZNF225	Homo sapiens (human)
OAS antiviral response	2',5'-phosphodiesterase 12 2'-5'-oligoadenylate synthase 1 2'-5'-oligoadenylate synthase 2 2'-5'-oligoadenylate synthase 3 2'-5'-oligoadenylate synthase-like protein 2-5A-dependent ribonuclease ATP-binding cassette sub-family E member 1 Antiviral innate immune response receptor RIG-I Filamin-A Protein VP3	B1NKT1 O95786 P00973 P21333 P29728 P61221 Q05823 Q15646 Q6L8Q7 Q9Y6K5	ABCE1 DDX58 FLN FLN1 FLNA OAS1 OAS2 OAS3 OASL OIAS PDE12 RIGI RLI RNASEL RNASEL1 RNASELI RNS4 RNS4I TRIP14	Homo sapiens (human)
Iron uptake and transport	Broad substrate specificity ATP-binding cassette transporter ABCG2 Ceruloplasmin Cullin-1 Cullin-associated NEDD8-dissociated protein 1 Cytoplasmic aconitate hydratase F-box/LRR-repeat protein 5 Ferritin heavy chain Ferritin light chain Ferritin, mitochondrial Glutaredoxin-3 Heme oxygenase 1 Heme oxygenase 2 Hephaestin Iron-responsive element-binding protein 2 NEDD8 Natural resistance-associated macrophage protein 2 Neutrophil gelatinase-associated lipocalin Plasma membrane ascorbate-dependent reductase CYBRD1 Polyubiquitin-B Polyubiquitin-C Proton-coupled folate transporter S-phase kinase-associated protein 1 Serotransferrin Solute carrier family 22 member 17 Solute carrier family 40 member 1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O76003 P00450 P02787 P02792 P02794 P09601 P0CG47 P0CG48 P21399 P30519 P48200 P49281 P62979 P62987 P63208 P80188 Q13616 Q15843 Q53TN4 Q86VP6 Q8N4E7 Q8WUG5 Q96NT5 Q9BQS7 Q9NP59 Q9UKA1 Q9UNQ0	ABCG2 ABCP ACO1 BCRP BCRP1 BOCT BOIT CAND1 CP CUL1 CYBRD1 DCT1 DCYTB DMT1 EMC19 FBL4 FBL5 FBXL5 FLR1 FPN FPN1 FRRS3 FTH FTH1 FTHL6 FTL FTMT G21 GLRX3 HCP1 HEPH HMOX1 HMOX2 HNL HO HO1 HO2 IREB1 IREB2 IREG1 KIAA0698 KIAA0829 LCN2 MXR NEDD8 NGAL NRAMP2 OCP2 PCFT PICOT RPS27A SKP1 SKP1A SLC11A2 SLC11A3 SLC22A17 SLC40A1 SLC46A1 TCEB1L TF TIP120 TIP120A TXNL2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Homo sapiens (human)
Heme biosynthesis	5-aminolevulinate synthase, erythroid-specific, mitochondrial 5-aminolevulinate synthase, non-specific, mitochondrial Albumin Broad substrate specificity ATP-binding cassette transporter ABCG2 Delta-aminolevulinic acid dehydratase Ferrochelatase, mitochondrial Heme A synthase COX15 Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial Porphobilinogen deaminase Protoheme IX farnesyltransferase, mitochondrial Protoporphyrinogen oxidase Uroporphyrinogen decarboxylase Uroporphyrinogen-III synthase	P02768 P06132 P08397 P10746 P13196 P13716 P22557 P22830 P36551 P50336 Q12887 Q7KZN9 Q9UNQ0	ABCG2 ABCP ALAD ALAS1 ALAS2 ALAS3 ALASE ALASH ALB ASB BCRP BCRP1 COX10 COX15 CPO CPOX CPX FECH HMBS MXR PBGD PPOX UPS UROD UROS	Homo sapiens (human)
Ciprofloxacin ADME	Albumin Broad substrate specificity ATP-binding cassette transporter ABCG2 Organic anion transporter 3 Solute carrier family 22 member 1 Solute carrier organic anion transporter family member 1A2	O15245 P02768 P46721 Q8TCC7 Q9UNQ0	ABCG2 ABCP ALB BCRP BCRP1 MXR OAT3 OATP OATP1 OATP1A2 OCT1 SLC21A3 SLC22A1 SLC22A8 SLCO1A2	Homo sapiens (human)
Defective ABCG8 causes GBD4 and sitosterolemia	ATP-binding cassette sub-family G member 5 ATP-binding cassette sub-family G member 8	Q9H221 Q9H222	ABCG5 ABCG8	Homo sapiens (human)
Defective ABCG5 causes sitosterolemia	ATP-binding cassette sub-family G member 5 ATP-binding cassette sub-family G member 8	Q9H221 Q9H222	ABCG5 ABCG8	Homo sapiens (human)
ALKBH3 mediated reversal of alkylation damage	Activating signal cointegrator 1 complex subunit 1 Activating signal cointegrator 1 complex subunit 2 Activating signal cointegrator 1 complex subunit 3 Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3	Q8N3C0 Q8N9N2 Q96Q83 Q9H1I8	ABH3 ALKBH3 ASC1P100 ASCC1 ASCC2 ASCC3 DEPC1 HELIC1 RQT2 RQT3	Homo sapiens (human)
Reversal of alkylation damage by DNA dioxygenases	Alpha-ketoglutarate-dependent dioxygenase FTO RNA demethylase ALKBH5	Q6P6C2 Q9C0B1	ABH5 ALKBH5 FTO KIAA1752 OFOXD1	Homo sapiens (human)
tRNA modification in the nucleus and cytosol	Alkylated DNA repair protein alkB homolog 8 Bifunctional glutamate/proline--tRNA ligase Cytoplasmic tRNA 2-thiolation protein 1 Cytoplasmic tRNA 2-thiolation protein 2 EKC/KEOPS complex subunit LAGE3 EKC/KEOPS complex subunit TP53RK EKC/KEOPS complex subunit TPRKB Multifunctional methyltransferase subunit TRM112-like protein Probable inactive tRNA-specific adenosine deaminase-like protein 3 Probable tRNA (uracil-O(2)-)-methyltransferase Probable tRNA methyltransferase 9B Probable tRNA(His) guanylyltransferase Pseudouridylate synthase 7 homolog Queuine tRNA-ribosyltransferase accessory subunit 2 Queuine tRNA-ribosyltransferase catalytic subunit 1 RNA cytosine C(5)-methyltransferase NSUN2 Threonylcarbamoyladenosine tRNA methylthiotransferase Ubiquitin-related modifier 1 tRNA (32-2'-O)-methyltransferase regulator THADA tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase tRNA (cytosine(38)-C(5))-methyltransferase tRNA (cytosine(72)-C(5))-methyltransferase NSUN6 tRNA (guanine(10)-N2)-methyltransferase homolog tRNA (guanine(26)-N(2))-dimethyltransferase tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4 tRNA (guanine-N(7)-)-methyltransferase tRNA N6-adenosine threonylcarbamoyltransferase tRNA dimethylallyltransferase tRNA methyltransferase 10 homolog A tRNA pseudouridine(38/39) synthase tRNA-dihydrouridine(20) synthase [NAD(P)+]-like tRNA-specific adenosine deaminase 1 tRNA-specific adenosine deaminase 2 tRNA	O14717 P07814 P57081 Q08J23 Q14657 Q2VPK5 Q5VV42 Q6YHU6 Q7Z4G4 Q7Z6V5 Q7Z7A3 Q8IYL2 Q8TBZ6 Q8TEA1 Q96BT7 Q96EY9 Q96FX7 Q96PZ0 Q96S44 Q9BTM9 Q9BUB4 Q9BXR0 Q9BZE2 Q9H3H1 Q9H974 Q9NPF4 Q9NUP7 Q9NWX6 Q9NX74 Q9NXH9 Q9P272 Q9UBP6 Q9UET6 Q9UI30 Q9UJA5 Q9Y3C4	ABH8 ADAT1 ADAT2 ADAT3 ALKBH8 ATPBD3 C12orf1 C14orf172 C16orf84 C20orf64 C4orf23 C6orf75 C8orf79 C9orf74 CCDC76 CDKAL1 CTU1 CTU2 DEADC1 DNMT2 DUS2 DUS2L DXS9879E EPRS EPRS1 ESO3 FTSJ1 GCPL1 GITA GLNS ICF45 IPT ITBA2 KIAA1153 KIAA1456 KIAA1767 KIAA1897 LAGE3 METTL1 METTL19 MOD5 NCS2 NCS6 NOPD1 NSUN2 NSUN6 OSGEP PARS PRPK PUS3 PUS7 QARS QPRS QTRT1 QTRT2 QTRTD1 RG9MTD2 SAKI TAD3 TGT TGUT THADA THG1L TP53RK TPRKB TRDMT1 TRIT1 TRM4 TRM6 TRM61 TRM9L TRMT1 TRMT10A TRMT11 TRMT112 TRMT13 TRMT44 TRMT6 TRMT61A TRMT9B URM1 WDR4	Homo sapiens (human)
Glucuronidation	Palmitoyl-protein thioesterase ABHD10, mitochondrial UDP-glucuronosyltransferase 1-6 UDP-glucuronosyltransferase 1A10 UDP-glucuronosyltransferase 1A1 UDP-glucuronosyltransferase 1A3 UDP-glucuronosyltransferase 1A4 UDP-glucuronosyltransferase 1A5 UDP-glucuronosyltransferase 1A7 UDP-glucuronosyltransferase 1A8 UDP-glucuronosyltransferase 1A9 UDP-glucuronosyltransferase 2A1 UDP-glucuronosyltransferase 2A2 UDP-glucuronosyltransferase 2A3 UDP-glucuronosyltransferase 2B10 UDP-glucuronosyltransferase 2B11 UDP-glucuronosyltransferase 2B15 UDP-glucuronosyltransferase 2B17 UDP-glucuronosyltransferase 2B28 UDP-glucuronosyltransferase 2B4 UDP-glucuronosyltransferase 2B7 UDP-glucuronosyltransferase 3A1 UDP-glucuronosyltransferase 3A2	O60656 O75310 O75795 P06133 P0DTE4 P0DTE5 P16662 P19224 P22309 P22310 P35503 P35504 P36537 P54855 Q3SY77 Q6NUS8 Q6UWM9 Q9BY64 Q9HAW7 Q9HAW8 Q9HAW9 Q9NUJ1	ABHD10 GNT1 UGT1 UGT1A1 UGT1A10 UGT1A3 UGT1A4 UGT1A5 UGT1A6 UGT1A7 UGT1A8 UGT1A9 UGT2A1 UGT2A2 UGT2A3 UGT2B10 UGT2B11 UGT2B15 UGT2B17 UGT2B28 UGT2B4 UGT2B7 UGT2B8 UGT3A1 UGT3A2 UGTB2B9	Homo sapiens (human)
Arachidonate production from DAG	Diacylglycerol lipase-alpha Diacylglycerol lipase-beta Lysophosphatidylserine lipase ABHD12 Monoacylglycerol lipase ABHD6 Monoglyceride lipase	Q8N2K0 Q8NCG7 Q99685 Q9BV23 Q9Y4D2	ABHD12 ABHD6 C11orf11 C20orf22 DAGLA DAGLB KIAA0659 MGLL NSDDR	Homo sapiens (human)
Cytosolic sulfonation of small molecules	3'(2'),5'-bisphosphate nucleotidase 1 Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase Podocalyxin-like protein 2 Protein-tyrosine sulfotransferase 1 Protein-tyrosine sulfotransferase 2 Putative protein-lysine deacylase ABHD14B Sulfotransferase 1A1 Sulfotransferase 1A2 Sulfotransferase 1A3 Sulfotransferase 1A4 Sulfotransferase 1B1 Sulfotransferase 1C2 Sulfotransferase 1C4 Sulfotransferase 1E1 Sulfotransferase 2A1 Sulfotransferase 4A1 Sulfotransferase 6B1	O00338 O43704 O60507 O60704 O75897 O95861 P0DMM9 P0DMN0 P49888 P50225 P50226 Q06520 Q6IMI4 Q96IU4 Q9BR01 Q9NX62 Q9NZ53	ABHD14B BPNT1 BPNT2 CIB HST IMPA3 IMPAD1 PODXL2 ST1B2 STD STE STM STP STP1 STP2 SULT1A1 SULT1A2 SULT1A3 SULT1A4 SULT1B1 SULT1B2 SULT1C1 SULT1C2 SULT1C4 SULT1E1 SULT2A1 SULT4A1 SULT6B1 SULTX3 TPST1 TPST2	Homo sapiens (human)
RAS processing	ADP-ribosylation factor-like protein 2 Acyl-protein thioesterase 1 Alpha/beta hydrolase domain-containing protein 17A Alpha/beta hydrolase domain-containing protein 17B Alpha/beta hydrolase domain-containing protein 17C Bcl-2-like protein 1 CAAX prenyl protease 2 Calmodulin-1 GTPase HRas GTPase KRas GTPase NRas Golgin subfamily A member 7 Palmitoyltransferase ZDHHC9 Protein farnesyltransferase subunit beta Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha Protein kinase C theta type Protein-S-isoprenylcysteine O-methyltransferase Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta Ubiquitin carboxyl-terminal hydrolase 17 cGMP-dependent protein kinase 2	O43924 O60725 O75608 P01111 P01112 P01116 P0DP23 P36404 P49354 P49356 Q04759 Q07817 Q13237 Q5VST6 Q6PCB6 Q6R6M4 Q7Z5G4 Q96GS6 Q9Y256 Q9Y397	ABHD17A ABHD17B ABHD17C APT1 ARL2 BCL2L BCL2L1 BCLX C19orf27 C9orf77 CALM CALM1 CAM CAM1 CXorf11 DUB3 FACE2 FAM108A1 FAM108B1 FAM108C1 FNTA FNTB GCP16 GOLGA7 HRAS HRAS1 ICMT KRAS KRAS2 LPL1 LYPLA1 NRAS PCCMT PDE6D PDED PRKCQ PRKCT PRKG2 PRKGR2 RASK2 RCE1 RCE1A RCE1B USP17 USP17H USP17I USP17J USP17K USP17L USP17L2 USP17M ZDHHC10 ZDHHC9 ZNF379 ZNF380	Homo sapiens (human)
Synthesis of PC	Acetylcholinesterase Casein kinase II subunit alpha' Casein kinase II subunit alpha Casein kinase II subunit beta Choline O-acetyltransferase Choline kinase alpha Choline transporter-like protein 1 Choline transporter-like protein 2 Choline transporter-like protein 3 Choline transporter-like protein 4 Choline transporter-like protein 5 Choline-phosphate cytidylyltransferase A Choline-phosphate cytidylyltransferase B Choline/ethanolamine kinase Choline/ethanolaminephosphotransferase 1 Cholinephosphotransferase 1 Cholinesterase Lysophosphatidylcholine acyltransferase 1 Phosphatidate phosphatase LPIN1 Phosphatidate phosphatase LPIN2 Phosphatidate phosphatase LPIN3 Phosphatidylcholine transfer protein Phosphatidylethanolamine N-methyltransferase Phosphoethanolamine/phosphocholine phosphatase Phospholipase ABHD3 START domain-containing protein 10 Sodium-dependent lysophosphatidylcholine symporter 1 StAR-related lipid transfer protein 7, mitochondrial	P06276 P19784 P22303 P28329 P35790 P49585 P67870 P68400 Q14693 Q53GD3 Q8IWA5 Q8N4M1 Q8NA29 Q8NCS7 Q8NF37 Q8TCT1 Q8WU67 Q8WUD6 Q8WWI5 Q92539 Q9BQK8 Q9NQZ5 Q9UBM1 Q9UKL6 Q9Y259 Q9Y365 Q9Y5K3 Q9Y6K0	ABHD3 ACHE AYTL2 BCHE C6orf29 CCTB CD92 CDW92 CEPT1 CHAT CHE1 CHETK CHK CHKA CHKB CHKL CHPT1 CK2A1 CK2A2 CK2N CKI CPT1 CSNK2A1 CSNK2A2 CSNK2B CTL1 CTL2 CTL3 CTL4 CTL5 CTPCT G5A GTT1 KIAA0188 KIAA0249 LIPN3L LPCAT1 LPIN1 LPIN2 LPIN3 MFSD2 MFSD2A NG22 NLS1 PCTP PCYT1 PCYT1A PCYT1B PEMPT PEMT PFAAP3 PHOSPHO1 PNMT SDCCAG28 SLC44A1 SLC44A2 SLC44A3 SLC44A4 SLC44A5 STARD10 STARD2 STARD7 TPPT1	Homo sapiens (human)
Acyl chain remodelling of PE	(Lyso)-N-acylphosphatidylethanolamine lipase 85/88 kDa calcium-independent phospholipase A2 Calcium-independent phospholipase A2-gamma Cytosolic phospholipase A2 beta Cytosolic phospholipase A2 delta Cytosolic phospholipase A2 epsilon Cytosolic phospholipase A2 gamma Cytosolic phospholipase A2 zeta Cytosolic phospholipase A2 Group 10 secretory phospholipase A2 Group 3 secretory phospholipase A2 Group IID secretory phospholipase A2 Group IIE secretory phospholipase A2 Group IIF secretory phospholipase A2 Group XIIA secretory phospholipase A2 Lysophospholipid acyltransferase 1 Lysophospholipid acyltransferase 2 Lysophospholipid acyltransferase 5 Lysophospholipid acyltransferase LPCAT4 Phospholipase A and acyltransferase 1 Phospholipase A and acyltransferase 2 Phospholipase A and acyltransferase 3 Phospholipase A and acyltransferase 4 Phospholipase A and acyltransferase 5 Phospholipase A2 group V Phospholipase A2, membrane associated Phospholipase A2 Phospholipase B-like 1 Secretory phospholipase A2 receptor	O15496 O60733 P04054 P0C869 P14555 P39877 P47712 P53816 Q13018 Q3MJ16 Q643R3 Q68DD2 Q6P1A2 Q6P4A8 Q6ZNC8 Q6ZWT7 Q86XP0 Q8TB40 Q96KN8 Q9BZM1 Q9BZM2 Q9HDD0 Q9NP80 Q9NWW9 Q9NZ20 Q9NZK7 Q9UL19 Q9UNK4 Q9UP65	ABHD4 AGPAT7 AYTL3 CLEC13C CPLA2 HRASLS HRASLS2 HRASLS3 HRASLS5 HREV107 HRLP5 IPLA22 IPLA2G LPCAT3 LPCAT4 LPEAT2 MBOAT1 MBOAT2 MBOAT5 OACT1 OACT2 OACT5 PLA2 PLA2A PLA2B PLA2G10 PLA2G12 PLA2G12A PLA2G16 PLA2G1B PLA2G2A PLA2G2D PLA2G2E PLA2G2F PLA2G3 PLA2G4 PLA2G4A PLA2G4B PLA2G4C PLA2G4D PLA2G4E PLA2G4F PLA2G5 PLA2G6 PLA2L PLA2R1 PLAAT1 PLAAT2 PLAAT3 PLAAT4 PLAAT5 PLBD1 PLPLA9 PNPLA8 PPLA2 RARRES3 RASF-A RIG1 SPLASH TIG3	Homo sapiens (human)
Triglyceride catabolism	1-acylglycerol-3-phosphate O-acyltransferase ABHD5 Caveolin-1 Fatty acid-binding protein 12 Fatty acid-binding protein 5 Fatty acid-binding protein 9 Fatty acid-binding protein, adipocyte Fatty acid-binding protein, brain Fatty acid-binding protein, heart Fatty acid-binding protein, intestinal Fatty acid-binding protein, liver Gastrotropin Glycerol-3-phosphate dehydrogenase, mitochondrial Hormone-sensitive lipase Monoglyceride lipase Patatin-like phospholipase domain-containing protein 4 Patatin-like phospholipase domain-containing protein 5 Perilipin-1 Perilipin-3 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Serine/threonine-protein phosphatase PP1-beta catalytic subunit Serine/threonine-protein phosphatase PP1-gamma catalytic subunit cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit gamma	A6NFH5 O15540 O60240 O60664 P05413 P07148 P12104 P15090 P17612 P22612 P22694 P36873 P41247 P43304 P51161 P62136 P62140 Q01469 Q03135 Q05469 Q0Z7S8 Q7Z6Z6 Q8WTS1 Q99685	ABHD5 BLBP CAV CAV1 DXS1283E FABP1 FABP11 FABP12 FABP2 FABP3 FABP4 FABP5 FABP6 FABP7 FABP9 FABPB FABPI FABPL GPD2 GS2 GS2L ILBP ILLBP LIPE M6PRBP1 MDGI MGLL MRG NCIE2 PERI PKACA PLIN PLIN1 PLIN3 PNPLA4 PNPLA5 PPP1A PPP1CA PPP1CB PPP1CC PRKACA PRKACB PRKACG TIP47	Homo sapiens (human)

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