GlyCosmos Portal

Homo sapiens (human)

Summary

Taxonomy ID: 9606
PubChem Taxonomy: 9606

Genes (1582) Glycans (5831) Glycoproteins (18496) Lectins (298) Pathways (2090)

Displaying entries **276 - 300** of **2090** in total

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Pathway Name	Protein Name ▲	UniProt ID	Gene Symbol
Purine catabolism	5'(3')-deoxyribonucleotidase, cytosolic type 5'-nucleotidase 5-hydroxymethyl-dUMP N-hydrolase Cytosolic 5'-nucleotidase 1A Cytosolic 5'-nucleotidase 1B Cytosolic purine 5'-nucleotidase Guanine deaminase Inosine triphosphate pyrophosphatase Purine nucleoside phosphorylase Xanthine dehydrogenase/oxidase	O43598 P00491 P21589 P47989 P49902 Q8TCD5 Q96P26 Q9BXI3 Q9BY32 Q9Y2T3	AIRP C20orf37 C6orf108 DNPH1 DNT1 GDA ITPA KIAA1258 NP NT5 NT5B NT5C NT5C1A NT5C1B NT5C2 NT5CP NT5E NTE PNP PNT5 RCL UMPH2 XDH XDHA
Synthesis of PG	5'-3' exonuclease PLD3 5'-3' exonuclease PLD4 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial Mitochondrial cardiolipin hydrolase Phosphatidate cytidylyltransferase 2 Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 Phospholipase D1 Phospholipase D2	O14939 O95674 Q13393 Q32NB8 Q8IV08 Q8N2A8 Q8WUK0 Q96BZ4	C14orf175 CDS2 MOSP PGS1 PLD1 PLD2 PLD3 PLD4 PLD6 PLIP PTPMT1
mRNA decay by 5' to 3' exoribonuclease	5'-3' exoribonuclease 1 Enhancer of mRNA-decapping protein 3 Enhancer of mRNA-decapping protein 4 Probable ATP-dependent RNA helicase DDX6 Protein PAT1 homolog 1 U6 snRNA-associated Sm-like protein LSm1 U6 snRNA-associated Sm-like protein LSm2 U6 snRNA-associated Sm-like protein LSm3 U6 snRNA-associated Sm-like protein LSm4 U6 snRNA-associated Sm-like protein LSm5 U6 snRNA-associated Sm-like protein LSm6 U6 snRNA-associated Sm-like protein LSm7 m7GpppN-mRNA hydrolase mRNA-decapping enzyme 1A mRNA-decapping enzyme 1B	O15116 P26196 P62310 P62312 Q6P2E9 Q86TB9 Q8IU60 Q8IZD4 Q8IZH2 Q96F86 Q9NPI6 Q9UK45 Q9Y333 Q9Y4Y9 Q9Y4Z0	C6orf28 CASM DCP1A DCP1B DCP2 DDX6 EDC3 EDC4 G7B HEDLS HLR2 LSM1 LSM16 LSM2 LSM3 LSM4 LSM5 LSM6 LSM7 NUDT20 PATL1 RCK SEP1 SMIF XRN1 YJDC YJEFN2
Association of TriC/CCT with target proteins during biosynthesis	5'-3' exoribonuclease 2 AP-3 complex subunit mu-1 Brefeldin A-inhibited guanine nucleotide-exchange protein 2 Cellular tumor antigen p53 DDB1- and CUL4-associated factor 7 F-box only protein 4 F-box only protein 6 F-box/LRR-repeat protein 3 F-box/LRR-repeat protein 5 F-box/WD repeat-containing protein 10 F-box/WD repeat-containing protein 2 F-box/WD repeat-containing protein 4 F-box/WD repeat-containing protein 5 F-box/WD repeat-containing protein 7 F-box/WD repeat-containing protein 9 G1/S-specific cyclin-E1 G1/S-specific cyclin-E2 Glyceraldehyde-3-phosphate dehydrogenase, testis-specific Histone deacetylase 3 Kinesin-like protein KIF13A Lon protease homolog 2, peroxisomal Lysosomal acid glucosylceramidase Nucleolar protein 56 Peptidyl-prolyl cis-trans isomerase FKBP9 Signal transducer and activator of transcription 3 Sphingosine kinase 1 Superkiller complex protein 2 T-complex protein 1 subunit alpha T-complex protein 1 subunit beta T-complex protein 1 subunit delta T-complex protein 1 subunit epsilon T-complex protein 1 subunit eta T-complex protein 1 subunit gamma T-complex protein 1 subunit theta T-complex protein 1 subunit zeta-2 T-complex protein 1 subunit zeta Telomerase Cajal body protein 1 Ubiquitin carboxyl-terminal hydrolase 11	O00567 O14556 O15379 O95302 O96020 P04062 P04637 P17987 P24864 P40227 P40763 P48643 P49368 P50990 P50991 P51784 P57775 P61962 P78371 Q15477 Q5XUX1 Q5XX13 Q86WA8 Q92526 Q969H0 Q969U6 Q99832 Q9BUR4 Q9H0D6 Q9H1H9 Q9NRD1 Q9NYA1 Q9UKA1 Q9UKT5 Q9UKT7 Q9UKT8 Q9Y2T2 Q9Y6D5	99D8.1 AP3M1 APRF ARFGEF2 ARFGEP2 BIG2 C21orf112 CCNE CCNE1 CCNE2 CCT1 CCT2 CCT3 CCT4 CCT5 CCT6 CCT6A CCT6B CCT7 CCT8 CCTA CCTB CCTD CCTE CCTG CCTH CCTQ CCTZ DCAF7 DDX13 FBG2 FBL3A FBL4 FBL5 FBS2 FBW2 FBW4 FBW5 FBW7 FBW9 FBX30 FBX4 FBX6 FBXL3 FBXL3A FBXL5 FBXO4 FBXO6 FBXW10 FBXW2 FBXW4 FBXW5 FBXW7 FBXW9 FKBP60 FKBP63 FKBP9 FLR1 FWD2 GAPD2 GAPDH2 GAPDHS GAPDS GBA GBA1 GC GLUC HAN11 HDAC3 KIAA0002 KIAA0098 KIF13A LONP LONP2 NIP7-1 NOL5A NOP56 P53 RBKIN SEL10 SHFM3 SK1 SKI2W SKIC2 SKIV2 SKIV2L SPHK SPHK1 SPK SRB STAT3 TCAB1 TCP1 TP53 TRIC5 UHX1 USP11 W WDR68 WDR79 WRAP53 XRN2
Regulation of TP53 Activity through Phosphorylation	5'-AMP-activated protein kinase catalytic subunit alpha-1 5'-AMP-activated protein kinase catalytic subunit alpha-2 5'-AMP-activated protein kinase subunit beta-1 5'-AMP-activated protein kinase subunit beta-2 5'-AMP-activated protein kinase subunit gamma-1 5'-AMP-activated protein kinase subunit gamma-2 5'-AMP-activated protein kinase subunit gamma-3 ATR-interacting protein Aurora kinase A Aurora kinase B BRCA1-associated RING domain protein 1 Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN Breast cancer type 1 susceptibility protein Casein kinase II subunit alpha' Casein kinase II subunit alpha Casein kinase II subunit beta Cell cycle checkpoint control protein RAD9A Cell cycle checkpoint control protein RAD9B Cell cycle checkpoint protein RAD17 Cell cycle checkpoint protein RAD1 Cellular tumor antigen p53 Checkpoint protein HUS1 Cyclin-A1 Cyclin-A2 Cyclin-dependent kinase 2 Cyclin-dependent kinase 5 activator 1 Cyclin-dependent kinase 5 DNA endonuclease RBBP8 DNA repair protein RAD50 DNA replication ATP-dependent helicase/nuclease DNA2 DNA topoisomerase 2-binding protein 1 DNA topoisomerase 3-alpha Double-strand break repair protein MRE11 Dual specificity tyrosine-phosphorylation-regulated kinase 2 E3 ubiquitin-protein ligase Mdm2 EKC/KEOPS complex subunit TP53RK Exonuclease 1 FACT complex subunit SPT16 FACT complex subunit SSRP1 Fanconi anemia group J protein Histone acetyltransferase KAT5 Homeodomain-interacting protein kinase 1 Homeodomain-interacting protein kinase 2 MAP kinase-activated protein kinase 5 Mitogen-activated protein kinase 11 Mitogen-activated protein kinase 14 NUAK family SNF1-like kinase 1 Nibrin Nucleolar complex protein 2 homolog Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Polyubiquitin-B Polyubiquitin-C Protein Mdm4 RAD9, HUS1, RAD1-interacting nuclear orphan protein 1 RecQ-like DNA helicase BLM RecQ-mediated genome instability protein 1 RecQ-mediated genome instability protein 2 Replication factor C subunit 2 Replication factor C subunit 3 Replication factor C subunit 4 Replication factor C subunit 5 Replication protein A 14 kDa subunit Replication protein A 32 kDa subunit Replication protein A 70 kDa DNA-binding subunit Serine-protein kinase ATM Serine/threonine-protein kinase ATR Serine/threonine-protein kinase Chk1 Serine/threonine-protein kinase Chk2 Serine/threonine-protein kinase PLK3 Serine/threonine-protein kinase STK11 TATA-binding protein-associated factor 2N TATA-box-binding protein Targeting protein for Xklp2 Transcription initiation factor TFIID subunit 1-like Transcription initiation factor TFIID subunit 10 Transcription initiation factor TFIID subunit 11 Transcription initiation factor TFIID subunit 12 Transcription initiation factor TFIID subunit 13 Transcription initiation factor TFIID subunit 1 Transcription initiation factor TFIID subunit 2 Transcription initiation factor TFIID subunit 3 Transcription initiation factor TFIID subunit 4 Transcription initiation factor TFIID subunit 4B Transcription initiation factor TFIID subunit 5 Transcription initiation factor TFIID subunit 6 Transcription initiation factor TFIID subunit 7-like Transcription initiation factor TFIID subunit 7 Transcription initiation factor TFIID subunit 9 Transcription initiation factor TFIID subunit 9B Tumor protein p53-inducible nuclear protein 1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00268 O14757 O14965 O15151 O43741 O60285 O60671 O60921 O60934 O75943 O96017 P04637 P0CG47 P0CG48 P15927 P19784 P20226 P20248 P21675 P24941 P27694 P35244 P35249 P35250 P38398 P40937 P40938 P49848 P49959 P51530 P54132 P54619 P54646 P62979 P62987 P67870 P68400 P78396 Q00535 Q00987 Q08945 Q12962 Q13131 Q13315 Q13472 Q13526 Q13535 Q14191 Q15078 Q15542 Q15543 Q15544 Q15545 Q15759 Q15831 Q16514 Q16539 Q16594 Q5H9L4 Q5VWG9 Q6P1X5 Q6WBX8 Q86Z02 Q8IW41 Q8IZX4 Q8WXE1 Q92547 Q92630 Q92750 Q92804 Q92878 Q92993 Q96A56 Q96E14 Q96GD4 Q96S44 Q99638 Q99708 Q99728 Q9BSD3 Q9BX63 Q9H2X6 Q9H4B4 Q9H9A7 Q9HBM6 Q9UGI9 Q9UGJ0 Q9ULW0 Q9UQ84 Q9Y3T9 Q9Y478 Q9Y5B9	AGS1 AIK AIK2 AIM1 AIRK1 AIRK2 AMPK AMPK1 AMPK2 AMPKG3 ARK1 ARK2 ARK5 ATM ATR ATRIP AURA AURKA AURKB AYK1 BA2R BACH1 BARD1 BLM BRCA1 BRIP1 BTAK C12orf32 C16orf75 C20orf1 C20orf2 C20orf64 C9orf76 CCG1 CCGS CCN1 CCNA CCNA1 CCNA2 CDK2 CDK5 CDK5R CDK5R1 CDKN2 CDKN5 CDS1 CHEK1 CHEK2 CHK1 CHK2 CIF150 CK2A1 CK2A2 CK2N CNK CSBP CSBP1 CSBP2 CSNK2A1 CSNK2A2 CSNK2B CSPB1 CTIP DIL2 DNA2 DNA2L DYRK2 EXO1 EXOI FACT140 FACT80 FACTP140 FANCJ FNK FRP1 G5A GTF2D1 HCA519 HEX1 HIPK1 HIPK2 HNGS1 HTATIP HUS1 IAK1 KAT5 KIAA0083 KIAA0259 KIAA0537 KIAA0630 LKB1 MAPK11 MAPK14 MAPKAPK5 MDM2 MDM4 MDMX MRE11 MRE11A MXI2 MYAK NBAK2 NBN NBS NBS1 NCK5A NIR NOC2L NUAK1 OMPHK1 P53 P53DINP1 P95 PIN1 PJS PLK3 PRAK PRK PRKAA1 PRKAA2 PRKAB1 PRKAB2 PRKAG1 PRKAG2 PRKAG3 PRKM11 PRPK PSSALRE R24L RAD1 RAD17 RAD50 RAD53 RAD9A RAD9B RBBP8 RBP56 REC1 RECQ2 RECQ3 RECQL2 RECQL3 REPA1 REPA2 REPA3 RFC2 RFC3 RFC4 RFC5 RHINO RHNO1 RMI1 RMI2 RNF53 RPA1 RPA14 RPA2 RPA3 RPA32 RPA34 RPA70 RPS27A SAPK2 SAPK2A SAPK2B SIP SSRP1 STK1 STK11 STK12 STK15 STK5 STK6 SUPT16H TAF1 TAF10 TAF11 TAF12 TAF13 TAF15 TAF1L TAF2 TAF2A TAF2B TAF2C TAF2C1 TAF2C2 TAF2D TAF2E TAF2F TAF2G TAF2H TAF2I TAF2J TAF2K TAF2N TAF2Q TAF3 TAF4 TAF4A TAF4B TAF5 TAF6 TAF7 TAF7L TAF9 TAF9B TAF9L TAFII105 TAFII130 TAFII135 TAFII18 TAFII20 TAFII30 TAFII31 TAFII55 TAFII70 TBP TF2D TFIID TIP60 TOP3 TOP3A TOPBP1 TP53 TP53INP1 TP53RK TPX2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 WRN
Macroautophagy	5'-AMP-activated protein kinase catalytic subunit alpha-1 5'-AMP-activated protein kinase catalytic subunit alpha-2 5'-AMP-activated protein kinase subunit beta-1 5'-AMP-activated protein kinase subunit beta-2 5'-AMP-activated protein kinase subunit gamma-1 5'-AMP-activated protein kinase subunit gamma-2 5'-AMP-activated protein kinase subunit gamma-3 Activating molecule in BECN1-regulated autophagy protein 1 Autophagy protein 5 Autophagy-related protein 101 Autophagy-related protein 13 Autophagy-related protein 16-1 Autophagy-related protein 9A Autophagy-related protein 9B Beclin 1-associated autophagy-related key regulator Beclin-1 Charged multivesicular body protein 2a Charged multivesicular body protein 2b Charged multivesicular body protein 3 Charged multivesicular body protein 4a Charged multivesicular body protein 4b Charged multivesicular body protein 4c Charged multivesicular body protein 6 Charged multivesicular body protein 7 Cysteine protease ATG4A Cysteine protease ATG4B Cysteine protease ATG4C Cysteine protease ATG4D Dynein light chain 1, cytoplasmic Dynein light chain 2, cytoplasmic GTP-binding protein Rheb Gamma-aminobutyric acid receptor-associated protein-like 1 Gamma-aminobutyric acid receptor-associated protein-like 2 Gamma-aminobutyric acid receptor-associated protein-like 3 Gamma-aminobutyric acid receptor-associated protein Hamartin Microtubule-associated proteins 1A/1B light chain 3A Microtubule-associated proteins 1A/1B light chain 3B Microtubule-associated proteins 1A/1B light chain 3C Myotubularin-related protein 14 Myotubularin-related protein 3 Neutral amino acid transporter 9 Phosphatidylinositol 3-kinase catalytic subunit type 3 Phosphoinositide 3-kinase regulatory subunit 4 RB1-inducible coiled-coil protein 1 Ragulator complex protein LAMTOR1 Ragulator complex protein LAMTOR2 Ragulator complex protein LAMTOR3 Ragulator complex protein LAMTOR4 Ragulator complex protein LAMTOR5 Ras-related GTP-binding protein A Ras-related GTP-binding protein B Ras-related GTP-binding protein C Ras-related GTP-binding protein D Regulatory-associated protein of mTOR Serine/threonine-protein kinase ULK1 Serine/threonine-protein kinase mTOR Target of rapamycin complex subunit LST8 Tuberin UV radiation resistance-associated gene protein Ubiquitin-like modifier-activating enzyme ATG7 Ubiquitin-like protein ATG12 Ubiquitin-like-conjugating enzyme ATG10 Ubiquitin-like-conjugating enzyme ATG3 WD repeat domain phosphoinositide-interacting protein 1 WD repeat domain phosphoinositide-interacting protein 2 WD repeat domain phosphoinositide-interacting protein 3 WD repeat domain phosphoinositide-interacting protein 4	O43504 O43633 O43741 O75143 O75385 O94817 O95166 O95352 P42345 P49815 P54619 P54646 P60520 P63167 Q0VGL1 Q13131 Q13615 Q14457 Q15382 Q5MNZ6 Q5MNZ9 Q5VZM2 Q674R7 Q676U5 Q6IAA8 Q6ZNE5 Q7L523 Q7Z3C6 Q86TL0 Q8N122 Q8NBW4 Q8NCE2 Q8NEB9 Q8TDY2 Q8WUX9 Q8WYN0 Q92574 Q96CF2 Q96DT6 Q96FJ2 Q96FZ7 Q99570 Q9BSB4 Q9BVC4 Q9BXW4 Q9BY43 Q9BY60 Q9C0C7 Q9GZQ8 Q9H0R8 Q9H0Y0 Q9H1Y0 Q9H444 Q9H492 Q9HB90 Q9NQL2 Q9NT62 Q9P2Y5 Q9UGI9 Q9UGJ0 Q9UHA4 Q9UQN3 Q9Y2Q5 Q9Y3E7 Q9Y478 Q9Y484 Q9Y4P1 Q9Y4P8	AMBRA1 AMPK AMPK1 AMPK2 AMPKG3 APG10L APG12 APG12L APG16L APG3 APG3L APG4A APG4B APG4C APG4D APG5L APG7L APG9L1 APG9L2 ASP ATG10 ATG101 ATG12 ATG13 ATG14 ATG14L ATG16L1 ATG3 ATG4A ATG4B ATG4C ATG4D ATG5 ATG7 ATG9A ATG9B AUTL1 AUTL2 AUTL3 AUTL4 BC2 BECN1 C11orf59 C12orf44 C14orf123 C20orf178 C3orf29 C7orf59 CGI149 CHMP2 CHMP2A CHMP2B CHMP3 CHMP4A CHMP4B CHMP4C CHMP6 CHMP7 DCAF3 DLC1 DLC2 DNCL1 DNCLC1 DYNLL1 DYNLL2 FLC3A FLC3B FRAP FRAP1 FRAP2 GABARAP GABARAPL1 GABARAPL2 GABARAPL3 GBL GEC1 GEF2 GT197 HBXIP HDLC1 KIAA0203 KIAA0243 KIAA0371 KIAA0652 KIAA0722 KIAA0831 KIAA0943 KIAA1303 KIAA1736 LAMTOR1 LAMTOR2 LAMTOR3 LAMTOR4 LAMTOR5 LST8 MAP1ALC3 MAP1LC3A MAP1LC3B MAP1LC3C MAP2K1IP1 MAPBPIP MAPKSP1 MLST8 MTMR14 MTMR3 MTOR NEDF NOS3AS PDRO PIK3C3 PIK3R4 PRKAA1 PRKAA2 PRKAB1 PRKAB2 PRKAG1 PRKAG2 PRKAG3 RAFT1 RAPT1 RAPTOR RB1CC1 RBICC RHEB RHEB2 ROBLD3 RPTOR RRAGA RRAGB RRAGC RRAGD SHAX1 SHAX2 SHAX3 SLC38A9 TSC TSC1 TSC2 TSC4 ULK1 URLC11 UVRAG VPS15 VPS20 VPS24 VPS34 WDR45 WDR45B WDR45L WDRX1 WDRXI4 WIPI1 WIPI2 WIPI3 WIPI4 WIPI49 XIP ZFYVE10
Energy dependent regulation of mTOR by LKB1-AMPK	5'-AMP-activated protein kinase catalytic subunit alpha-1 5'-AMP-activated protein kinase catalytic subunit alpha-2 5'-AMP-activated protein kinase subunit beta-1 5'-AMP-activated protein kinase subunit beta-2 5'-AMP-activated protein kinase subunit gamma-1 5'-AMP-activated protein kinase subunit gamma-2 5'-AMP-activated protein kinase subunit gamma-3 Calcium-binding protein 39-like Calcium-binding protein 39 GTP-binding protein Rheb Hamartin Neutral amino acid transporter 9 Protein phosphatase 1A Ragulator complex protein LAMTOR1 Ragulator complex protein LAMTOR2 Ragulator complex protein LAMTOR3 Ragulator complex protein LAMTOR4 Ragulator complex protein LAMTOR5 Ras-related GTP-binding protein A Ras-related GTP-binding protein B Ras-related GTP-binding protein C Ras-related GTP-binding protein D Regulatory-associated protein of mTOR STE20-related kinase adapter protein alpha STE20-related kinase adapter protein beta Serine/threonine-protein kinase STK11 Serine/threonine-protein kinase mTOR Target of rapamycin complex subunit LST8 Tuberin	O43504 O43741 P35813 P42345 P49815 P54619 P54646 Q0VGL1 Q13131 Q15382 Q15831 Q5VZM2 Q6IAA8 Q7L523 Q7RTN6 Q8N122 Q8NBW4 Q92574 Q9BVC4 Q9C0K7 Q9H9S4 Q9HB90 Q9NQL2 Q9UGI9 Q9UGJ0 Q9UHA4 Q9Y2Q5 Q9Y376 Q9Y478	ALS2CR2 AMPK AMPK1 AMPK2 AMPKG3 C11orf59 C7orf59 CAB39 CAB39L FRAP FRAP1 FRAP2 GBL HBXIP ILPIP KIAA0243 KIAA1303 LAMTOR1 LAMTOR2 LAMTOR3 LAMTOR4 LAMTOR5 LKB1 LST8 LYK5 MAP2K1IP1 MAPBPIP MAPKSP1 MLST8 MO25 MTOR PDRO PJS PPM1A PPPM1A PRKAA1 PRKAA2 PRKAB1 PRKAB2 PRKAG1 PRKAG2 PRKAG3 RAFT1 RAPT1 RAPTOR RHEB RHEB2 ROBLD3 RPTOR RRAGA RRAGB RRAGC RRAGD SLC38A9 STK11 STRAD STRADA STRADB TSC TSC1 TSC2 TSC4 URLC11 XIP
Activation of AMPK downstream of NMDARs	5'-AMP-activated protein kinase catalytic subunit alpha-1 5'-AMP-activated protein kinase catalytic subunit alpha-2 5'-AMP-activated protein kinase subunit beta-1 5'-AMP-activated protein kinase subunit beta-2 5'-AMP-activated protein kinase subunit gamma-1 5'-AMP-activated protein kinase subunit gamma-2 5'-AMP-activated protein kinase subunit gamma-3 Calcium/calmodulin-dependent protein kinase kinase 2 Calmodulin-1	O43741 P0DP23 P54619 P54646 Q13131 Q96RR4 Q9UGI9 Q9UGJ0 Q9Y478	AMPK AMPK1 AMPK2 AMPKG3 CALM CALM1 CAM CAM1 CAMKK2 CAMKKB KIAA0787 PRKAA1 PRKAA2 PRKAB1 PRKAB2 PRKAG1 PRKAG2 PRKAG3
Lipophagy	5'-AMP-activated protein kinase catalytic subunit alpha-2 5'-AMP-activated protein kinase subunit beta-1 5'-AMP-activated protein kinase subunit beta-2 5'-AMP-activated protein kinase subunit gamma-1 5'-AMP-activated protein kinase subunit gamma-2 5'-AMP-activated protein kinase subunit gamma-3 Heat shock cognate 71 kDa protein Perilipin-2 Perilipin-3	O43741 O60664 P11142 P54619 P54646 Q99541 Q9UGI9 Q9UGJ0 Q9Y478	ADFP AMPK AMPK2 AMPKG3 HSC70 HSP73 HSPA10 HSPA8 M6PRBP1 PLIN2 PLIN3 PRKAA2 PRKAB1 PRKAB2 PRKAG1 PRKAG2 PRKAG3 TIP47
Activation of PPARGC1A (PGC-1alpha) by phosphorylation	5'-AMP-activated protein kinase catalytic subunit alpha-2 5'-AMP-activated protein kinase subunit beta-1 5'-AMP-activated protein kinase subunit beta-2 5'-AMP-activated protein kinase subunit gamma-1 5'-AMP-activated protein kinase subunit gamma-2 5'-AMP-activated protein kinase subunit gamma-3 Mitogen-activated protein kinase 11 Mitogen-activated protein kinase 12 Mitogen-activated protein kinase 14 Peroxisome proliferator-activated receptor gamma coactivator 1-alpha	O43741 P53778 P54619 P54646 Q15759 Q16539 Q9UBK2 Q9UGI9 Q9UGJ0 Q9Y478	AMPK AMPK2 AMPKG3 CSBP CSBP1 CSBP2 CSPB1 ERK6 LEM6 MAPK11 MAPK12 MAPK14 MXI2 PGC1 PGC1A PPARGC1 PPARGC1A PRKAA2 PRKAB1 PRKAB2 PRKAG1 PRKAG2 PRKAG3 PRKM11 SAPK2 SAPK2A SAPK2B SAPK3
AMPK inhibits chREBP transcriptional activation activity	5'-AMP-activated protein kinase catalytic subunit alpha-2 5'-AMP-activated protein kinase subunit beta-2 5'-AMP-activated protein kinase subunit gamma-2 Adiponectin receptor protein 1 Adiponectin receptor protein 2 Adiponectin Carbohydrate-responsive element-binding protein Serine/threonine-protein kinase STK11	O43741 P54646 Q15831 Q15848 Q86V24 Q96A54 Q9NP71 Q9UGJ0	ACDC ACRP30 ADIPOQ ADIPOR1 ADIPOR2 AMPK AMPK2 APM1 BHLHD14 GBP28 LKB1 MIO MLXIPL PAQR1 PAQR2 PJS PRKAA2 PRKAB2 PRKAG2 STK11 TESBP1A WBSCR14
Carnitine metabolism	5'-AMP-activated protein kinase catalytic subunit alpha-2 5'-AMP-activated protein kinase subunit beta-2 5'-AMP-activated protein kinase subunit gamma-2 Carnitine O-palmitoyltransferase 1, liver isoform Carnitine O-palmitoyltransferase 1, muscle isoform Carnitine O-palmitoyltransferase 2, mitochondrial Mid1-interacting protein 1 Mitochondrial carnitine/acylcarnitine carrier protein Organic cation/carnitine transporter 2 Peroxisome proliferator-activated receptor delta Retinoic acid receptor RXR-alpha Thyroid hormone-inducible hepatic protein	O43741 O43772 O76082 P19793 P23786 P50416 P54646 Q03181 Q92523 Q92748 Q9NPA3 Q9UGJ0	AMPK AMPK2 CAC CACT CPT1 CPT1A CPT1B CPT2 KIAA1670 MID1IP1 MIG12 NR1C2 NR2B1 OCTN2 PPARB PPARD PRKAA2 PRKAB2 PRKAG2 RXRA SLC22A5 SLC25A20 THRSP
Nuclear events mediated by NFE2L2	5'-AMP-activated protein kinase catalytic subunit alpha-2 CREB-binding protein Histone acetyltransferase p300 Kelch-like ECH-associated protein 1 Nuclear factor erythroid 2-related factor 2 Sequestosome-1 Transcription factor MafG Transcription factor MafK Tumor suppressor ARF	O15525 O60675 P54646 Q09472 Q13501 Q14145 Q16236 Q8N726 Q92793	AMPK AMPK2 CBP CDKN2 CDKN2A CREBBP EP300 INRF2 KEAP1 KIAA0132 KLHL19 MAFG MAFK MLM NFE2L2 NRF2 ORCA OSIL P300 PRKAA2 SQSTM1
Nicotinate metabolism	5'-nucleotidase ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 Glutamine-dependent NAD(+) synthetase NAD kinase 2, mitochondrial NAD kinase Nicotinamide riboside kinase 1 Nicotinamide riboside kinase 2 Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2 Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 Nicotinate-nucleotide pyrophosphorylase [carboxylating]	O95544 P21589 P28907 Q10588 Q15274 Q4G0N4 Q6IA69 Q96T66 Q9BZQ4 Q9HAN9 Q9NPI5 Q9NWW6	BST1 C1orf15 C5orf33 C9orf95 CD38 ITGB1BP3 KIAA0479 MNADK NADK NADK2 NADKD1 NADSYN1 NMNAT NMNAT1 NMNAT2 NMNAT3 NMRK1 NMRK2 NRK1 NRK2 NT5 NT5E NTE QPRT
Purinergic signaling in leishmaniasis infection	5'-nucleotidase Apoptosis-associated speck-like protein containing a CARD C3a anaphylatoxin chemotactic receptor Caspase-1 Cathepsin G Complement C3 Ectonucleoside triphosphate diphosphohydrolase 1 Gasdermin-D Heat shock protein HSP 90-beta Heme oxygenase 1 Interleukin-1 alpha Interleukin-1 beta Interleukin-18 NACHT, LRR and PYD domains-containing protein 3 Nuclear factor NF-kappa-B p100 subunit Nuclear factor NF-kappa-B p105 subunit Nucleoside diphosphate phosphatase ENTPD5 P2X purinoceptor 4 P2X purinoceptor 7 Proline-serine-threonine phosphatase-interacting protein 1 Protein SGT1 homolog Pyrin Thioredoxin-interacting protein Thioredoxin Transcription factor p65	O15553 O43586 O75356 P01024 P01583 P01584 P08238 P08311 P09601 P10599 P19838 P21589 P29466 P49961 P57764 Q00653 Q04206 Q14116 Q16581 Q96P20 Q99571 Q99572 Q9H3M7 Q9ULZ3 Q9Y2Z0	ASC AZ3B C1orf7 C3 C3AR1 C3R1 CARD5 CASP1 CD2BP1 CD39 CD39L4 CIAS1 CPAMD1 CTSG DFNA5L ENTPD1 ENTPD5 GSDMD GSDMDC1 HMOX1 HNFAG09 HO HO1 HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB IGIF IL18 IL1A IL1B IL1BC IL1BCE IL1F1 IL1F2 IL1F4 LYT10 MEF MEFV NALP3 NFKB1 NFKB2 NFKB3 NLRP3 NT5 NT5E NTE P2RX4 P2RX7 PCPH PSTPIP1 PYCARD PYPAF1 RELA SUGT1 TMS1 TRDX TRIM20 TRX TRX1 TXN TXNIP VDUP1
Regulation of MITF-M-dependent genes involved in pigmentation	5,6-dihydroxyindole-2-carboxylic acid oxidase AT-rich interactive domain-containing protein 1A AT-rich interactive domain-containing protein 1B Actin, cytoplasmic 1 Actin-like protein 6A B-cell CLL/lymphoma 7 protein family member A B-cell CLL/lymphoma 7 protein family member B B-cell CLL/lymphoma 7 protein family member C Calcium-responsive transactivator Catenin beta-1 G-protein coupled receptor 143 L-dopachrome tautomerase Lymphoid enhancer-binding factor 1 Melanocyte protein PMEL Melanoma antigen recognized by T-cells 1 Probable global transcription activator SNF2L2 Protein SSXT RAC-beta serine/threonine-protein kinase Ras-related protein Rab-27A SWI/SNF complex subunit SMARCC1 SWI/SNF complex subunit SMARCC2 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 Transcription activator BRG1 Transcription factor SOX-10 Tyrosinase Unconventional myosin-Va Upstream stimulatory factor 1 Zinc finger protein DPF3 Zinc finger protein neuro-d4 Zinc finger protein ubi-d4	O14497 O75177 O96019 P14679 P17643 P22415 P31751 P35222 P40126 P40967 P51159 P51531 P51532 P51810 P56693 P60709 Q12824 Q15532 Q16655 Q4VC05 Q6STE5 Q8NFD5 Q8TAQ2 Q8WUZ0 Q92782 Q92784 Q92785 Q92922 Q92925 Q969G3 Q96GM5 Q9BQE9 Q9UJU2 Q9Y4I1	ACTB ACTL6A AKT2 ARID1A ARID1B BAF155 BAF170 BAF190A BAF190B BAF250 BAF250A BAF250B BAF45B BAF45C BAF45D BAF47 BAF53 BAF53A BAF57 BAF60A BAF60B BAF60C BCL7A BCL7B BCL7C BHLHB11 BRG1 BRM C1orf4 CAS2 CERD4 CREST CTNNB CTNNB1 D12S53E DAN15 DCT DPF1 DPF2 DPF3 GPR143 INI1 INO80K KIAA0693 KIAA1235 LEF1 MART1 MLANA MYH12 MYO5A NEUD4 OA1 OSA1 OSA2 PMEL PMEL17 RAB27 RAB27A REQ SILV SMARCA2 SMARCA4 SMARCB1 SMARCC1 SMARCC2 SMARCD1 SMARCD2 SMARCD3 SMARCE1 SMARCF1 SNF2A SNF2B SNF2L2 SNF2L4 SNF5L1 SOX10 SS18 SS18L1 SSXT SYT TYR TYRP TYRP1 TYRP2 TYRRP UBID4 USF USF1
Melanin biosynthesis	5,6-dihydroxyindole-2-carboxylic acid oxidase L-dopachrome tautomerase Membrane-associated transporter protein P protein Tyrosinase	P14679 P17643 P40126 Q04671 Q9UMX9	AIM1 CAS2 D15S12 DCT MATP OCA2 P SLC45A2 TYR TYRP TYRP1 TYRP2 TYRRP
Heme biosynthesis	5-aminolevulinate synthase, erythroid-specific, mitochondrial 5-aminolevulinate synthase, non-specific, mitochondrial Albumin Broad substrate specificity ATP-binding cassette transporter ABCG2 Delta-aminolevulinic acid dehydratase Ferrochelatase, mitochondrial Heme A synthase COX15 Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial Porphobilinogen deaminase Protoheme IX farnesyltransferase, mitochondrial Protoporphyrinogen oxidase Uroporphyrinogen decarboxylase Uroporphyrinogen-III synthase	P02768 P06132 P08397 P10746 P13196 P13716 P22557 P22830 P36551 P50336 Q12887 Q7KZN9 Q9UNQ0	ABCG2 ABCP ALAD ALAS1 ALAS2 ALAS3 ALASE ALASH ALB ASB BCRP BCRP1 COX10 COX15 CPO CPOX CPX FECH HMBS MXR PBGD PPOX UPS UROD UROS
Metabolism of folate and pterines	5-formyltetrahydrofolate cyclo-ligase Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2, mitochondrial Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial C-1-tetrahydrofolate synthase, cytoplasmic Cytosolic 10-formyltetrahydrofolate dehydrogenase Dihydrofolate reductase 2, mitochondrial Dihydrofolate reductase Folate receptor beta Methylenetetrahydrofolate reductase (NADPH) Mitochondrial 10-formyltetrahydrofolate dehydrogenase Monofunctional C1-tetrahydrofolate synthase, mitochondrial Proton-coupled folate transporter Reduced folate transporter Serine hydroxymethyltransferase, cytosolic Serine hydroxymethyltransferase, mitochondrial Solute carrier family 25 member 32	O75891 P00374 P11586 P13995 P14207 P34896 P34897 P41440 P42898 P49914 Q3SY69 Q6UB35 Q86XF0 Q96NT5 Q9H2D1 Q9H903	ALDH1L1 ALDH1L2 DHFR DHFR2 DHFRL1 DHFRP4 FLOT1 FOLR2 FTHFD FTHFSDC1 G21 HCP1 MFT MFTC MTHFC MTHFD MTHFD1 MTHFD1L MTHFD2 MTHFD2L MTHFR MTHFS NMDMC PCFT RFC1 SHMT1 SHMT2 SLC19A1 SLC25A32 SLC46A1
Serotonin receptors	5-hydroxytryptamine receptor 1A 5-hydroxytryptamine receptor 1B 5-hydroxytryptamine receptor 1D 5-hydroxytryptamine receptor 1E 5-hydroxytryptamine receptor 1F 5-hydroxytryptamine receptor 2A 5-hydroxytryptamine receptor 2B 5-hydroxytryptamine receptor 2C 5-hydroxytryptamine receptor 4 5-hydroxytryptamine receptor 5A 5-hydroxytryptamine receptor 6 5-hydroxytryptamine receptor 7	P08908 P28221 P28222 P28223 P28335 P28566 P30939 P34969 P41595 P47898 P50406 Q13639	ADRB2RL1 ADRBRL1 HTR1A HTR1B HTR1C HTR1D HTR1DA HTR1DB HTR1E HTR1EL HTR1F HTR2 HTR2A HTR2B HTR2C HTR4 HTR5A HTR6 HTR7 HTRL
Neurotransmitter receptors and postsynaptic signal transmission	5-hydroxytryptamine receptor 3A 5-hydroxytryptamine receptor 3B 5-hydroxytryptamine receptor 3C 5-hydroxytryptamine receptor 3D 5-hydroxytryptamine receptor 3E Glycine receptor subunit alpha-1 Glycine receptor subunit alpha-2 Glycine receptor subunit alpha-3 Glycine receptor subunit beta Neurobeachin	A5X5Y0 O75311 O95264 P23415 P23416 P46098 P48167 Q70Z44 Q8NFP9 Q8WXA8	5HT3R BCL8B GLRA1 GLRA2 GLRA3 GLRB HTR3 HTR3A HTR3B HTR3C HTR3D HTR3E KIAA1544 LYST2 NBEA
rRNA modification in the mitochondrion	5-methylcytosine rRNA methyltransferase NSUN4 Dimethyladenosine transferase 1, mitochondrial Transcription termination factor 4, mitochondrial rRNA methyltransferase 1, mitochondrial rRNA methyltransferase 2, mitochondrial rRNA methyltransferase 3, mitochondrial	Q6IN84 Q7Z6M4 Q8WVM0 Q96CB9 Q9HC36 Q9UI43	FJH1 FTSJ2 MRM1 MRM2 MRM3 MTERF4 MTERFD2 NSUN4 RNMTL1 TFB1M
Glutathione synthesis and recycling	5-oxoprolinase Cytosolic non-specific dipeptidase Gamma-glutamylcyclotransferase Glutamate--cysteine ligase catalytic subunit Glutamate--cysteine ligase regulatory subunit Glutathione hydrolase 1 proenzyme Glutathione hydrolase 5 proenzyme Glutathione hydrolase 6 Glutathione hydrolase 7 Glutathione synthetase Glutathione-specific gamma-glutamylcyclotransferase 1 Glutathione-specific gamma-glutamylcyclotransferase 2 Putative glutathione hydrolase 3 proenzyme	A6NGU5 O14841 O75223 P19440 P36269 P48506 P48507 P48637 Q6P531 Q8WUX2 Q96KP4 Q9BUX1 Q9UJ14	BOTCH C7orf24 CHAC1 CHAC2 CN2 CNDP2 CPGL CRF21 GCLC GCLM GGCT GGT GGT1 GGT3 GGT3P GGT5 GGT6 GGT7 GGTL3 GGTL5 GGTLA1 GLCL GLCLC GLCLR GSS HEL-S-13 OPLAH PEPA
Defective OPLAH causes OPLAHD	5-oxoprolinase	O14841	OPLAH
Collagen degradation	5-phosphohydroxy-L-lysine phospho-lyase 72 kDa type IV collagenase Cathepsin B Cathepsin D Cathepsin K Collagen alpha-1(IX) chain Collagen alpha-1(XII) chain Collagen alpha-1(XIII) chain Collagen alpha-1(XIV) chain Collagen alpha-1(XIX) chain Collagen alpha-1(XV) chain Collagen alpha-1(XVI) chain Collagen alpha-1(XVII) chain Collagen alpha-1(XVIII) chain Collagen alpha-1(XXIII) chain Collagen alpha-1(XXV) chain Collagen alpha-1(XXVI) chain Collagen alpha-2(IX) chain Collagen alpha-3(IX) chain Collagenase 3 Disintegrin and metalloproteinase domain-containing protein 10 Disintegrin and metalloproteinase domain-containing protein 17 Disintegrin and metalloproteinase domain-containing protein 9 Furin Interstitial collagenase Macrophage metalloelastase Matrilysin Matrix metalloproteinase-14 Matrix metalloproteinase-15 Matrix metalloproteinase-19 Matrix metalloproteinase-20 Matrix metalloproteinase-9 Neutrophil collagenase Neutrophil elastase Procathepsin L Stromelysin-1 Stromelysin-2 Stromelysin-3 Transmembrane protease serine 6 Trypsin-2	O14672 O60882 P03956 P07339 P07478 P07711 P07858 P08246 P08253 P08254 P09237 P09238 P09958 P14780 P20849 P22894 P24347 P39059 P39060 P39900 P43235 P45452 P50281 P51511 P78536 Q05707 Q07092 Q13443 Q14050 Q14055 Q14993 Q5TAT6 Q86Y22 Q8IU80 Q8IUZ5 Q96A83 Q99542 Q99715 Q9BXS0 Q9UMD9	ADAM10 ADAM17 ADAM9 AGXT2L2 BP180 BPAG2 CLG CLG1 CLG4A CLG4B COL12A1 COL12A1L COL13A1 COL14A1 COL15A1 COL16A1 COL17A1 COL18A1 COL19A1 COL23A1 COL25A1 COL26A1 COL9A1 COL9A2 COL9A3 CPSB CPSD CSVP CTSB CTSD CTSK CTSL CTSL1 CTSO CTSO2 ELA2 ELANE EMID2 EMU2 FUR FURIN HME KIAA0021 KUZ MADM MCMP MDC9 MLTNG MMP1 MMP10 MMP11 MMP12 MMP13 MMP14 MMP15 MMP18 MMP19 MMP2 MMP20 MMP3 MMP7 MMP8 MMP9 MPSL1 PACE PCSK3 PHYKPL PRSS2 PUMP1 RASI STMY1 STMY2 STMY3 TACE TMPRSS6 TRY2 TRYP2 UND

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