GlyCosmos Portal

Homo sapiens (human)

Summary

Taxonomy ID: 9606
PubChem Taxonomy: 9606

Genes (1582) Glycans (5831) Glycoproteins (18496) Lectins (298) Pathways (2090)

Displaying entries **601 - 625** of **2090** in total

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Pathway Name	Protein Name	UniProt ID ▲	Gene Symbol
Opsins	Long-wave-sensitive opsin 1 Medium-wave-sensitive opsin 1 Melanopsin Opsin-3 Opsin-5 RPE-retinal G protein-coupled receptor Rhodopsin Short-wave-sensitive opsin 1 Visual pigment-like receptor peropsin	O14718 P03999 P04000 P04001 P08100 P47804 Q6U736 Q9H1Y3 Q9UHM6	BCP ECPN GCP GPR136 MOP OPN1LW OPN1MW OPN1SW OPN2 OPN3 OPN4 OPN5 PGR12 RCP RGR RHO RRH TMEM13
TP53 Regulates Transcription of Caspase Activators and Caspases	Apoptotic protease-activating factor 1 Caspase-10 Caspase-1 Caspase-2 Caspase-6 Cellular tumor antigen p53 Death domain-containing protein CRADD NLR family CARD domain-containing protein 4 Serine-protein kinase ATM Tumor protein 63 Tumor protein p73 p53-induced death domain-containing protein 1	O14727 O15350 P04637 P29466 P42575 P55212 P78560 Q13315 Q92851 Q9H3D4 Q9HB75 Q9NPP4	APAF1 ATM CARD12 CASP1 CASP10 CASP2 CASP6 CLAN CLAN1 CRADD ICH1 IL1BC IL1BCE IPAF KET KIAA0413 LRDD MCH2 MCH4 NEDD2 NLRC4 P53 P63 P73 P73H P73L PIDD PIDD1 RAIDD TP53 TP63 TP73 TP73L
Regulation of the apoptosome activity	Apoptotic protease-activating factor 1 Caspase recruitment domain-containing protein 8 Caspase-9 Cell death regulator Aven Cytochrome c Diablo IAP-binding mitochondrial protein E3 ubiquitin-protein ligase XIAP Methylthioribulose-1-phosphate dehydratase Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Uveal autoantigen with coiled-coil domains and ankyrin repeats	O14727 P27361 P28482 P55211 P98170 P99999 Q96GX9 Q9BZF9 Q9NQS1 Q9NR28 Q9Y2G2	APAF1 API3 APIP AVEN BIRC4 CARD8 CASP9 CYC CYCS DACAR DIABLO ERK1 ERK2 IAP3 KIAA0413 KIAA0955 KIAA1561 MAPK1 MAPK3 MCH6 NDPP1 PRKM1 PRKM2 PRKM3 SMAC UACA XIAP
SMAC (DIABLO) binds to IAPs	Apoptotic protease-activating factor 1 Caspase-3 Caspase-7 Caspase-9 Cytochrome c Diablo IAP-binding mitochondrial protein E3 ubiquitin-protein ligase XIAP	O14727 P42574 P55210 P55211 P98170 P99999 Q9NR28	APAF1 API3 BIRC4 CASP3 CASP7 CASP9 CPP32 CYC CYCS DIABLO IAP3 KIAA0413 MCH3 MCH6 SMAC XIAP
SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes	Apoptotic protease-activating factor 1 Caspase-3 Caspase-7 Caspase-9 Cytochrome c Diablo IAP-binding mitochondrial protein E3 ubiquitin-protein ligase XIAP	O14727 P42574 P55210 P55211 P98170 P99999 Q9NR28	APAF1 API3 BIRC4 CASP3 CASP7 CASP9 CPP32 CYC CYCS DIABLO IAP3 KIAA0413 MCH3 MCH6 SMAC XIAP
Activation of caspases through apoptosome-mediated cleavage	Apoptotic protease-activating factor 1 Caspase-3 Caspase-7 Caspase-9 Cytochrome c E3 ubiquitin-protein ligase XIAP	O14727 P42574 P55210 P55211 P98170 P99999	APAF1 API3 BIRC4 CASP3 CASP7 CASP9 CPP32 CYC CYCS IAP3 KIAA0413 MCH3 MCH6 XIAP
Formation of apoptosome	Apoptotic protease-activating factor 1 Caspase recruitment domain-containing protein 8 Caspase-9 Cell death regulator Aven Cytochrome c Methylthioribulose-1-phosphate dehydratase	O14727 P55211 P99999 Q96GX9 Q9NQS1 Q9Y2G2	APAF1 APIP AVEN CARD8 CASP9 CYC CYCS DACAR KIAA0413 KIAA0955 MCH6 NDPP1
Synthesis of IP2, IP, and Ins in the cytosol	Inositol monophosphatase 1 Inositol monophosphatase 2 Inositol oxygenase Inositol polyphosphate 1-phosphatase Inositol polyphosphate 4-phosphatase type II Inositol polyphosphate 5-phosphatase OCRL Inositol polyphosphate-4-phosphatase type I A Inositol polyphosphate-5-phosphatase A Inositol-3-phosphate synthase 1 Myotubularin-related protein 7 Myotubularin-related protein 9 Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A Synaptojanin-1 Type II inositol 1,4,5-trisphosphate 5-phosphatase	O14732 O15327 O43426 P29218 P32019 P49441 Q01968 Q14642 Q15735 Q96PE3 Q96QG7 Q9NPH2 Q9UGB7 Q9Y216	5PTASE ALDRL6 C8orf9 IMP.18P IMPA IMPA1 IMPA2 INO1 INPP1 INPP4A INPP4B INPP5A INPP5B INPP5J ISYNA1 KIAA0910 KSP32 MIOX MTMR7 MTMR8 MTMR9 OCRL OCRL1 OCRL2 PIB5PA PIPP RSOR SYNJ1
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1	Dual specificity mitogen-activated protein kinase kinase 4 Dual specificity mitogen-activated protein kinase kinase 7 Interleukin-1 receptor-associated kinase 1 Interleukin-1 receptor-associated kinase-like 2 Mitogen-activated protein kinase 10 Mitogen-activated protein kinase 8 Mitogen-activated protein kinase 9 Mitogen-activated protein kinase kinase kinase 7 NF-kappa-B essential modulator Nucleotide-binding oligomerization domain-containing protein 1 Nucleotide-binding oligomerization domain-containing protein 2 Receptor-interacting serine/threonine-protein kinase 2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 TNF receptor-associated factor 6 Ubiquitin-conjugating enzyme E2 N Ubiquitin-conjugating enzyme E2 variant 1	O14733 O43187 O43318 O43353 P45983 P45984 P45985 P51617 P53779 P61088 Q13404 Q15750 Q8N5C8 Q9HC29 Q9NYJ8 Q9Y239 Q9Y4K3 Q9Y6K9	BLU CARD15 CARD4 CARDIAK CROC1 FIP3 IKBKG IRAK IRAK1 IRAK2 JNK1 JNK2 JNK3 JNK3A JNKK1 JNKK2 KIAA0733 MAP2K4 MAP2K7 MAP3K7 MAP3K7IP1 MAP3K7IP2 MAP3K7IP3 MAPK10 MAPK8 MAPK9 MEK4 MEK7 MKK4 MKK7 NEMO NOD1 NOD2 PRKM10 PRKM8 PRKM9 PRKMK4 PRKMK7 RICK RIP2 RIPK2 RNF85 SAPK1 SAPK1A SAPK1B SAPK1C SEK1 SERK1 SKK1 SKK4 TAB1 TAB2 TAB3 TAK1 TRAF6 UBE2N UBE2V UBE2V1 UEV1
Uptake and function of anthrax toxins	Calmodulin-1 Calmodulin-sensitive adenylate cyclase Dual specificity mitogen-activated protein kinase kinase 1 Dual specificity mitogen-activated protein kinase kinase 2 Dual specificity mitogen-activated protein kinase kinase 4 Dual specificity mitogen-activated protein kinase kinase 7 Furin Lethal factor Programmed cell death 6-interacting protein Protective antigen	O14733 P09958 P0DP23 P13423 P15917 P36507 P40136 P45985 Q02750 Q8WUM4	AIP1 ALIX CALM CALM1 CAM CAM1 FUR FURIN JNKK1 JNKK2 KIAA1375 MAP2K1 MAP2K2 MAP2K4 MAP2K7 MEK1 MEK2 MEK4 MEK7 MKK2 MKK4 MKK7 PACE PCSK3 PDCD6IP PRKMK1 PRKMK2 PRKMK4 PRKMK7 SEK1 SERK1 SKK1 SKK4 cya lef pag pagA
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol	3 beta-hydroxysteroid dehydrogenase type 7 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase Acyl-coenzyme A thioesterase 8 Aldo-keto reductase family 1 member C1 Aldo-keto reductase family 1 member C2 Aldo-keto reductase family 1 member C3 Aldo-keto reductase family 1 member C4 Aldo-keto reductase family 1 member D1 Alpha-methylacyl-CoA racemase Bile acid receptor Bile acid-CoA Bile salt export pump Cytochrome P450 7A1 Cytochrome P450 7B1 Long-chain fatty acid transport protein 2 Long-chain fatty acid transport protein 5 Nuclear receptor coactivator 1 Nuclear receptor coactivator 2 Peroxisomal acyl-coenzyme A oxidase 2 Peroxisomal multifunctional enzyme type 2 Prostacyclin synthase Retinoic acid receptor RXR-alpha Sterol 26-hydroxylase, mitochondrial	O14734 O14975 O75881 O95342 P17516 P19793 P22680 P42330 P51659 P51857 P52895 Q02318 Q04828 Q14032 Q15596 Q15788 Q16647 Q96RI1 Q99424 Q9H2F3 Q9UHK6 Q9UNU6 Q9Y2P5	ABCB11 ACOT8 ACOX2 ACSB ACSVL1 ACSVL6 ACTEIII AKR1C1 AKR1C2 AKR1C3 AKR1C4 AKR1D1 AMACR BAAT BAR BHLHE74 BHLHE75 BSEP CHDR CYP12 CYP27 CYP27A1 CYP7 CYP7A1 CYP7B1 CYP8 CYP8A1 CYP8B1 DDH DDH1 DDH2 EDH17B4 FACVL1 FACVL3 FATP2 FATP5 FXR HRR1 HSD17B4 HSD17B5 HSD3B7 KIAA0119 NCOA1 NCOA2 NR1H4 NR2B1 PGFS PTE1 PTGIS RIP14 RXRA SDR8C1 SLC27A2 SLC27A5 SRC1 SRC2 SRD5B1 TIF2 VLACS
Beta-oxidation of pristanoyl-CoA	Acyl-coenzyme A oxidase-like protein Acyl-coenzyme A thioesterase 8 Alpha-methylacyl-CoA racemase Carnitine O-acetyltransferase Peroxisomal acyl-coenzyme A oxidase 2 Peroxisomal acyl-coenzyme A oxidase 3 Peroxisomal carnitine O-octanoyltransferase Peroxisomal multifunctional enzyme type 2	O14734 O15254 P43155 P51659 Q99424 Q9NUZ1 Q9UHK6 Q9UKG9	ACOT8 ACOX2 ACOX3 ACOXL ACTEIII AMACR BRCOX CAT1 COT CRAT CROT EDH17B4 HSD17B4 PRCOX PTE1 SDR8C1
alpha-linolenic acid (ALA) metabolism	3-ketoacyl-CoA thiolase, peroxisomal ATP-binding cassette sub-family D member 1 Acyl-CoA (8-3)-desaturase Acyl-CoA 6-desaturase Acyl-coenzyme A thioesterase 8 Long-chain-fatty-acid--CoA ligase 1 Peroxisomal multifunctional enzyme type 2 Sterol carrier protein 2 Very long chain fatty acid elongase 1 Very long chain fatty acid elongase 2 Very long chain fatty acid elongase 3 Very long chain fatty acid elongase 5	O14734 O60427 O95864 P09110 P22307 P33121 P33897 P51659 Q9BW60 Q9HB03 Q9NXB9 Q9NYP7	ABCD1 ACAA ACAA1 ACOT8 ACSL1 ACTEIII ALD CIG30 EDH17B4 ELG3 ELOVL1 ELOVL2 ELOVL3 ELOVL5 FACL1 FACL2 FADS1 FADS2 FADSD5 HSD17B4 LACS LACS1 LACS2 PTE1 PTHIO SCP2 SDR8C1 SSC1 SSC2
Beta-oxidation of very long chain fatty acids	3-ketoacyl-CoA thiolase, peroxisomal ATP-binding cassette sub-family D member 1 Acyl-coenzyme A thioesterase 6 Acyl-coenzyme A thioesterase 8 Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing] Peroxisomal bifunctional enzyme Peroxisomal multifunctional enzyme type 2 Peroxisomal succinyl-coenzyme A thioesterase	O14734 P09110 P33897 P51659 Q08426 Q3I5F7 Q8N9L9 Q9NUI1	ABCD1 ACAA ACAA1 ACOT4 ACOT6 ACOT8 ACTEIII ALD C14orf42 DECR2 ECHD EDH17B4 EHHADH HSD17B4 PDCR PTE1 PTE2B PTEIB PTHIO SDR17C1 SDR8C1
Regulation of TP53 Activity through Methylation	Cellular tumor antigen p53 E3 ubiquitin-protein ligase Mdm2 Histone acetyltransferase p300 Histone-lysine N-methyltransferase EHMT1 Histone-lysine N-methyltransferase EHMT2 Junction-mediating and -regulatory protein Lethal(3)malignant brain tumor-like protein 1 N-lysine methyltransferase KMT5A N-lysine methyltransferase SMYD2 Polyubiquitin-B Polyubiquitin-C Protein Mdm4 Protein arginine N-methyltransferase 5 SET domain-containing protein 9 Serine-protein kinase ATM Serine/threonine-protein kinase Chk2 Tetratricopeptide repeat protein 5 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O14744 O15151 O96017 P04637 P0CG47 P0CG48 P62979 P62987 Q00987 Q09472 Q13315 Q8N0Z6 Q8N9B5 Q8NE22 Q96KQ7 Q9H9B1 Q9NQR1 Q9NRG4 Q9Y468	ATM BAT8 C5orf35 C6orf30 CDS1 CHEK2 CHK2 EHMT1 EHMT2 EP300 EUHMTASE1 G9A GLP HRMT1L5 IBP72 JBP1 JMY KIAA0681 KIAA1876 KMT1C KMT1D KMT3C KMT5A L3MBT L3MBTL L3MBTL1 MDM2 MDM4 MDMX NG36 P300 P53 PRMT5 PRSET7 RAD53 RPS27A SET07 SET8 SETD8 SETD9 SKB1 SMYD2 TP53 TTC5 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2
Regulation of MITF-M-dependent genes involved in DNA damage repair and senescence	DNA ligase 1 Telomerase reverse transcriptase	O14746 P18858	EST2 LIG1 TCS1 TERT TRT
The canonical retinoid cycle in rods (twilight vision)	17-beta-hydroxysteroid dehydrogenase type 1 17-beta-hydroxysteroid dehydrogenase type 6 Cytochrome P450 4V2 Dehydrogenase/reductase SDR family member 9 Lecithin retinol acyltransferase Receptor for retinol uptake STRA6 Retinal-specific phospholipid-transporting ATPase ABCA4 Retinaldehyde-binding protein 1 Retinoid isomerohydrolase Retinol dehydrogenase 10 Retinol dehydrogenase 11 Retinol dehydrogenase 12 Retinol dehydrogenase 16 Retinol dehydrogenase 5 Retinol dehydrogenase 8 Retinol-binding protein 1 Retinol-binding protein 3 Retinol-binding protein 4 Rhodopsin Short-chain dehydrogenase/reductase family 9C member 7 Transthyretin Unconventional myosin-VIIa	O14756 O75452 O95237 P02753 P02766 P08100 P09455 P10745 P12271 P14061 P78363 Q13402 Q16518 Q6ZWL3 Q8IZV5 Q8NEX9 Q8TC12 Q92781 Q96NR8 Q9BPW9 Q9BX79 Q9NYR8	ABCA4 ABCR ARSDR1 CRALBP CRBP1 CYP4V2 DHRS9 E17KSR EDH17B1 EDH17B2 EDHB17 HSD17B1 HSD17B6 HSD17B9 LRAT MYO7A OPN2 PALB PRRDH PSDR1 RBP1 RBP3 RBP4 RDH1 RDH10 RDH11 RDH12 RDH15 RDH16 RDH5 RDH8 RDHS RHO RLBP1 RODH RODH4 RPE65 SDR16C4 SDR28C1 SDR28C2 SDR7C1 SDR7C2 SDR9C4 SDR9C5 SDR9C6 SDR9C7 SDR9C8 SDRO STRA6 TTR USH1B
Presynaptic phase of homologous DNA pairing and strand exchange	26S proteasome complex subunit SEM1 ATR-interacting protein BRCA1-associated RING domain protein 1 Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN Breast cancer type 1 susceptibility protein Breast cancer type 2 susceptibility protein Cell cycle checkpoint control protein RAD9A Cell cycle checkpoint control protein RAD9B Cell cycle checkpoint protein RAD17 Cell cycle checkpoint protein RAD1 Checkpoint protein HUS1 DNA endonuclease RBBP8 DNA repair protein RAD50 DNA repair protein RAD51 homolog 1 DNA repair protein RAD51 homolog 2 DNA repair protein RAD51 homolog 3 DNA repair protein RAD51 homolog 4 DNA repair protein XRCC2 DNA replication ATP-dependent helicase/nuclease DNA2 DNA topoisomerase 2-binding protein 1 DNA topoisomerase 3-alpha Double-strand break repair protein MRE11 Exonuclease 1 Fanconi anemia group J protein Histone acetyltransferase KAT5 Nibrin RAD9, HUS1, RAD1-interacting nuclear orphan protein 1 RecQ-like DNA helicase BLM RecQ-mediated genome instability protein 1 RecQ-mediated genome instability protein 2 Replication factor C subunit 2 Replication factor C subunit 3 Replication factor C subunit 4 Replication factor C subunit 5 Replication protein A 14 kDa subunit Replication protein A 32 kDa subunit Replication protein A 70 kDa DNA-binding subunit Serine-protein kinase ATM Serine/threonine-protein kinase ATR Serine/threonine-protein kinase Chk1	O14757 O15315 O43502 O43543 O60671 O60921 O60934 O75771 O75943 P15927 P27694 P35244 P35249 P35250 P38398 P40937 P40938 P49959 P51530 P51587 P54132 P60896 Q06609 Q13315 Q13472 Q13535 Q14191 Q6WBX8 Q8WXE1 Q92547 Q92878 Q92993 Q96E14 Q99638 Q99708 Q99728 Q9BSD3 Q9BX63 Q9H9A7 Q9UQ84	AGS1 ATM ATR ATRIP BACH1 BARD1 BLM BRCA1 BRCA2 BRIP1 C12orf32 C16orf75 C7orf76 C9orf76 CHEK1 CHK1 CTIP DNA2 DNA2L DSS1 EXO1 EXOI FACD FANCD1 FANCJ FRP1 HEX1 HNGS1 HTATIP HUS1 KAT5 KIAA0083 KIAA0259 MRE11 MRE11A NBN NBS NBS1 P95 R24L RAD1 RAD17 RAD50 RAD51 RAD51A RAD51B RAD51C RAD51D RAD51L1 RAD51L2 RAD51L3 RAD9A RAD9B RBBP8 REC1 REC2 RECA RECQ2 RECQ3 RECQL2 RECQL3 REPA1 REPA2 REPA3 RFC2 RFC3 RFC4 RFC5 RHINO RHNO1 RMI1 RMI2 RNF53 RPA1 RPA14 RPA2 RPA3 RPA32 RPA34 RPA70 SEM1 SHFDG1 SHFM1 TIP60 TOP3 TOP3A TOPBP1 WRN XRCC2
G2/M DNA damage checkpoint	ATR-interacting protein BRCA1-A complex subunit Abraxas 1 BRCA1-A complex subunit RAP80 BRCA1-associated RING domain protein 1 BRISC and BRCA1-A complex member 1 BRISC and BRCA1-A complex member 2 Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN Breast cancer type 1 susceptibility protein Cell cycle checkpoint control protein RAD9A Cell cycle checkpoint control protein RAD9B Cell cycle checkpoint protein RAD17 Cell cycle checkpoint protein RAD1 Cellular tumor antigen p53 Checkpoint protein HUS1 DNA endonuclease RBBP8 DNA repair protein RAD50 DNA replication ATP-dependent helicase/nuclease DNA2 DNA topoisomerase 2-binding protein 1 DNA topoisomerase 3-alpha Double-strand break repair protein MRE11 E3 SUMO-protein ligase PIAS4 E3 ubiquitin-protein ligase HERC2 E3 ubiquitin-protein ligase RNF168 E3 ubiquitin-protein ligase RNF8 Exonuclease 1 Fanconi anemia group J protein Histone H2AX Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/F/G/I Histone H2B type 1-D Histone H2B type 1-H Histone H2B type 1-J Histone H2B type 1-K Histone H2B type 1-L Histone H2B type 1-M Histone H2B type 1-N Histone H2B type 1-O Histone H2B type 2-E Histone H2B type 3-B Histone H2B type F-S Histone H3.1t Histone H4 Histone acetyltransferase KAT5 Histone-lysine N-methyltransferase NSD2 Lys-63-specific deubiquitinase BRCC36 Mediator of DNA damage checkpoint protein 1 Nibrin RAD9, HUS1, RAD1-interacting nuclear orphan protein 1 RecQ-like DNA helicase BLM RecQ-mediated genome instability protein 1 RecQ-mediated genome instability protein 2 Replication factor C subunit 2 Replication factor C subunit 3 Replication factor C subunit 4 Replication factor C subunit 5 Replication protein A 14 kDa subunit Replication protein A 32 kDa subunit Replication protein A 70 kDa DNA-binding subunit Serine-protein kinase ATM Serine/threonine-protein kinase ATR Serine/threonine-protein kinase Chk1 Serine/threonine-protein kinase Chk2 TP53-binding protein 1 Ubiquitin-conjugating enzyme E2 N Ubiquitin-conjugating enzyme E2 variant 2	O14757 O60671 O60814 O60921 O60934 O75943 O76064 O95714 O96017 O96028 P04637 P06899 P15927 P16104 P23527 P27694 P33778 P35244 P35249 P35250 P38398 P40937 P40938 P46736 P49959 P51530 P54132 P57053 P58876 P61088 P62805 P62807 Q12888 Q13315 Q13472 Q13535 Q14191 Q14676 Q15819 Q16695 Q16778 Q6UWZ7 Q6WBX8 Q8IYW5 Q8N257 Q8N2W9 Q8WXE1 Q92547 Q92878 Q92993 Q93079 Q96A08 Q96E14 Q96RL1 Q99638 Q99708 Q99728 Q99877 Q99879 Q99880 Q9BSD3 Q9BX63 Q9H9A7 Q9NWV8 Q9NXR7 Q9UQ84	ABRA1 ABRAXAS1 AGS1 ATM ATR ATRIP BABAM1 BABAM2 BACH1 BARD1 BLM BLU BRCA1 BRCC3 BRCC36 BRCC45 BRE BRIP1 C12orf32 C16orf75 C19orf62 C6.1A C9orf76 CCDC98 CDS1 CHEK1 CHEK2 CHK1 CHK2 CTIP CXorf53 DNA2 DNA2L EXO1 EXOI FAM175A FANCJ FRP1 H2AFX H2AX H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H2BFA H2BFB H2BFC H2BFD H2BFE H2BFF H2BFG H2BFH H2BFJ H2BFK H2BFL H2BFN H2BFQ H2BFR H2BFS H2BFT H2BS1 H2BU1 H3-4 H3FT H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HERC2 HEX1 HIRIP1 HIRIP2 HIST1H2BA HIST1H2BB HIST1H2BC HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2BI HIST1H2BJ HIST1H2BK HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H2BE HIST2H4 HIST2H4A HIST2H4B HIST3H2BB HIST3H3 HIST4H4 HNGS1 HTATIP HUS1 KAT5 KIAA0083 KIAA0170 KIAA0259 KIAA0646 KIAA1090 MDC1 MERIT40 MMS2 MMSET MRE11 MRE11A NBA1 NBN NBS NBS1 NFBD1 NSD2 P53 P95 PIAS4 PIASG R24L RAD1 RAD17 RAD50 RAD53 RAD9A RAD9B RAP80 RBBP8 REC1 RECQ2 RECQ3 RECQL2 RECQL3 REPA1 REPA2 REPA3 RFC2 RFC3 RFC4 RFC5 RHINO RHNO1 RMI1 RMI2 RNF168 RNF53 RNF8 RPA1 RPA14 RPA2 RPA3 RPA32 RPA34 RPA70 RXRIP110 TIP60 TOP3 TOP3A TOPBP1 TP53 TP53BP1 TRX5 TSH2B UBE2N UBE2V2 UEV2 UIMC1 WHSC1 WRN
Processing of DNA double-strand break ends	ATR-interacting protein BRCA1-A complex subunit Abraxas 1 BRCA1-A complex subunit RAP80 BRCA1-associated RING domain protein 1 BRISC and BRCA1-A complex member 1 BRISC and BRCA1-A complex member 2 Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN Breast cancer type 1 susceptibility protein Cell cycle checkpoint control protein RAD9A Cell cycle checkpoint control protein RAD9B Cell cycle checkpoint protein RAD17 Cell cycle checkpoint protein RAD1 Checkpoint protein HUS1 Claspin Cyclin-A1 Cyclin-A2 Cyclin-dependent kinase 2 DNA endonuclease RBBP8 DNA repair protein RAD50 DNA replication ATP-dependent helicase/nuclease DNA2 DNA topoisomerase 2-binding protein 1 DNA topoisomerase 3-alpha Double-strand break repair protein MRE11 E3 SUMO-protein ligase PIAS4 E3 ubiquitin-protein ligase HERC2 E3 ubiquitin-protein ligase RNF168 E3 ubiquitin-protein ligase RNF4 E3 ubiquitin-protein ligase RNF8 Exonuclease 1 Fanconi anemia group J protein Histone H2AX Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/F/G/I Histone H2B type 1-D Histone H2B type 1-H Histone H2B type 1-J Histone H2B type 1-K Histone H2B type 1-L Histone H2B type 1-M Histone H2B type 1-N Histone H2B type 1-O Histone H2B type 2-E Histone H2B type 3-B Histone H2B type F-S Histone H3.1t Histone H4 Histone acetyltransferase KAT5 Histone-lysine N-methyltransferase NSD2 Lys-63-specific deubiquitinase BRCC36 Mediator of DNA damage checkpoint protein 1 NAD-dependent protein deacylase sirtuin-6 Nibrin Polyubiquitin-B Polyubiquitin-C Protein timeless homolog RAD9, HUS1, RAD1-interacting nuclear orphan protein 1 RecQ-like DNA helicase BLM RecQ-mediated genome instability protein 1 RecQ-mediated genome instability protein 2 Replication factor C subunit 2 Replication factor C subunit 3 Replication factor C subunit 4 Replication factor C subunit 5 Replication protein A 14 kDa subunit Replication protein A 32 kDa subunit Replication protein A 70 kDa DNA-binding subunit SUMO-conjugating enzyme UBC9 Serine-protein kinase ATM Serine/threonine-protein kinase ATR Serine/threonine-protein kinase Chk1 Serine/threonine-protein phosphatase 4 catalytic subunit Serine/threonine-protein phosphatase 4 regulatory subunit 2 Small ubiquitin-related modifier 2 TIMELESS-interacting protein TP53-binding protein 1 Ubiquitin-conjugating enzyme E2 N Ubiquitin-conjugating enzyme E2 variant 2 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O14757 O60671 O60814 O60921 O60934 O75943 O76064 O95714 O96028 P06899 P0CG47 P0CG48 P15927 P16104 P20248 P23527 P24941 P27694 P33778 P35244 P35249 P35250 P38398 P40937 P40938 P46736 P49959 P51530 P54132 P57053 P58876 P60510 P61088 P61956 P62805 P62807 P62979 P62987 P63279 P78317 P78396 Q12888 Q13315 Q13472 Q13535 Q14191 Q14676 Q15819 Q16695 Q16778 Q6UWZ7 Q6WBX8 Q8IYW5 Q8N257 Q8N2W9 Q8N6T7 Q8WXE1 Q92547 Q92878 Q92993 Q93079 Q96A08 Q96E14 Q96RL1 Q99638 Q99708 Q99728 Q99877 Q99879 Q99880 Q9BSD3 Q9BVW5 Q9BX63 Q9H9A7 Q9HAW4 Q9NWV8 Q9NXR7 Q9NY27 Q9UNS1 Q9UQ84	ABRA1 ABRAXAS1 AGS1 ATM ATR ATRIP BABAM1 BABAM2 BACH1 BARD1 BLM BLU BRCA1 BRCC3 BRCC36 BRCC45 BRE BRIP1 C12orf32 C16orf75 C19orf62 C6.1A C9orf76 CCDC98 CCN1 CCNA CCNA1 CCNA2 CDK2 CDKN2 CHEK1 CHK1 CLSPN CTIP CXorf53 DNA2 DNA2L EXO1 EXOI FAM175A FANCJ FRP1 H2AFX H2AX H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H2BFA H2BFB H2BFC H2BFD H2BFE H2BFF H2BFG H2BFH H2BFJ H2BFK H2BFL H2BFN H2BFQ H2BFR H2BFS H2BFT H2BS1 H2BU1 H3-4 H3FT H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HERC2 HEX1 HIRIP1 HIRIP2 HIST1H2BA HIST1H2BB HIST1H2BC HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2BI HIST1H2BJ HIST1H2BK HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H2BE HIST2H4 HIST2H4A HIST2H4B HIST3H2BB HIST3H3 HIST4H4 HNGS1 HTATIP HUS1 KAT5 KIAA0083 KIAA0170 KIAA0259 KIAA0646 KIAA1090 MDC1 MERIT40 MMS2 MMSET MRE11 MRE11A NBA1 NBN NBS NBS1 NFBD1 NSD2 P95 PIAS4 PIASG PPP4 PPP4C PPP4R2 PPX R24L RAD1 RAD17 RAD50 RAD9A RAD9B RAP80 RBBP8 REC1 RECQ2 RECQ3 RECQL2 RECQL3 REPA1 REPA2 REPA3 RFC2 RFC3 RFC4 RFC5 RHINO RHNO1 RMI1 RMI2 RNF168 RNF4 RNF53 RNF8 RPA1 RPA14 RPA2 RPA3 RPA32 RPA34 RPA70 RPS27A RXRIP110 SIR2L6 SIRT6 SMT3B SMT3H2 SNURF SUMO2 TIM TIM1 TIMELESS TIMELESS1 TIP60 TIPIN TOP3 TOP3A TOPBP1 TP53BP1 TRX5 TSH2B UBA52 UBA80 UBB UBC UBC9 UBCE9 UBCEP1 UBCEP2 UBE2I UBE2N UBE2V2 UEV2 UIMC1 WHSC1 WRN
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex	14-3-3 protein beta/alpha 14-3-3 protein epsilon 14-3-3 protein eta 14-3-3 protein gamma 14-3-3 protein sigma 14-3-3 protein theta 14-3-3 protein zeta/delta Cyclin-dependent kinase 1 G2/mitotic-specific cyclin-B1 M-phase inducer phosphatase 3 Serine/threonine-protein kinase Chk1 Serine/threonine-protein kinase Chk2 Wee1-like protein kinase	O14757 O96017 P06493 P14635 P27348 P30291 P30307 P31946 P31947 P61981 P62258 P63104 Q04917	CCNB CCNB1 CDC2 CDC25C CDC28A CDK1 CDKN1 CDS1 CHEK1 CHEK2 CHK1 CHK2 HME1 P34CDC2 RAD53 SFN WEE1 YWHA1 YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion	FERM, ARHGEF and pleckstrin domain-containing protein 2 Neuropilin-1 Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma Plexin-A1 Plexin-A2 Plexin-A3 Plexin-A4 Ras-related C3 botulinum toxin substrate 1 Ras-related protein R-Ras Rho-related GTP-binding protein Rho6 Semaphorin-3A Talin-1 Tyrosine-protein kinase Fes/Fps Tyrosine-protein kinase Fyn	O14786 O60331 O75051 O94887 P06241 P07332 P10301 P51805 P63000 Q14563 Q92730 Q9HCM2 Q9UIW2 Q9Y490	FARP2 FES FPS FYN KIAA0463 KIAA0589 KIAA0793 KIAA1027 KIAA1550 NOV NRP NRP1 OCT PIP5K1C PLEKHC3 PLXN1 PLXN2 PLXN4 PLXNA1 PLXNA2 PLXNA3 PLXNA4 PLXNA4A PLXNA4B RAC1 RHO6 RND1 RRAS SEMA3A SEMAD SEX TC25 TLN TLN1 VEGF165R
Neurophilin interactions with VEGF and VEGFR	Neuropilin-1 Neuropilin-2 Vascular endothelial growth factor receptor 1 Vascular endothelial growth factor receptor 2	O14786 O60462 P17948 P35968	FLK1 FLT FLT1 FRT KDR NRP NRP1 NRP2 VEGF165R VEGF165R2 VEGFR1 VEGFR2
Sema3A PAK dependent Axon repulsion	Cofilin-1 Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta LIM domain kinase 1 Neuropilin-1 Plexin-A1 Plexin-A2 Plexin-A3 Plexin-A4 Ras-related C3 botulinum toxin substrate 1 Semaphorin-3A Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 2 Serine/threonine-protein kinase PAK 3 Tyrosine-protein kinase Fes/Fps Tyrosine-protein kinase Fyn	O14786 O75051 O75914 P06241 P07332 P07900 P08238 P23528 P51805 P53667 P63000 Q13153 Q13177 Q14563 Q9HCM2 Q9UIW2	CFL CFL1 FES FPS FYN HSP90A HSP90AA1 HSP90AB1 HSP90B HSPC1 HSPC2 HSPC3 HSPCA HSPCB KIAA0463 KIAA1550 LIMK LIMK1 NOV NRP NRP1 OCT OPHN3 PAK1 PAK2 PAK3 PLXN1 PLXN2 PLXN4 PLXNA1 PLXNA2 PLXNA3 PLXNA4 PLXNA4A PLXNA4B RAC1 SEMA3A SEMAD SEX TC25 VEGF165R
Signaling by ROBO receptors	C-X-C chemokine receptor type 4 Ena/VASP-like protein Glypican-1 Leucine-rich repeat transmembrane protein FLRT3 Neuropilin-1 Profilin-1 Profilin-2 Protein enabled homolog Roundabout homolog 1 Roundabout homolog 2 Slit homolog 1 protein Slit homolog 2 protein Slit homolog 3 protein Stromal cell-derived factor 1 Vasodilator-stimulated phosphoprotein	O14786 O75093 O75094 O94813 P07737 P35052 P35080 P48061 P50552 P61073 Q8N8S7 Q9HCK4 Q9NZU0 Q9UI08 Q9Y6N7	CXCL12 CXCR4 DUTT1 ENAH EVL FLRT3 GPC1 KIAA0813 KIAA0814 KIAA1469 KIAA1568 MEGF4 MEGF5 MENA NRP NRP1 PFN1 PFN2 RNB6 ROBO1 ROBO2 SDF1 SDF1A SDF1B SLIL1 SLIL2 SLIL3 SLIT1 SLIT2 SLIT3 VASP VEGF165R

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