GlyCosmos Portal

Homo sapiens (human)

Summary

Taxonomy ID: 9606
PubChem Taxonomy: 9606

Genes (10109) Glycans (5831) Glycoproteins (15837) Lectins (297) Pathways (2074)

Displaying entries **651 - 675** of **2074** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol
LXRs regulate gene expression linked to gluconeogenesis	Nuclear receptor-interacting protein 1 Oxysterols receptor LXR-alpha Phosphoenolpyruvate carboxykinase, cytosolic [GTP] Retinoic acid receptor RXR-alpha Retinoic acid receptor RXR-beta	P19793 P28702 P35558 P48552 Q13133	LXRA NR1H3 NR2B1 NR2B2 NRIP1 PCK1 PEPCK1 RXRA RXRB
p75NTR negatively regulates cell cycle via SC1	Beta-nerve growth factor Histone deacetylase 1 Histone deacetylase 2 Histone deacetylase 3 PR domain zinc finger protein 4 Tumor necrosis factor receptor superfamily member 16	O15379 P01138 P08138 Q13547 Q92769 Q9UKN5	HDAC1 HDAC2 HDAC3 NGF NGFB NGFR PFM1 PRDM4 RPD3L1 TNFRSF16
RNA Polymerase III Transcription Initiation From Type 3 Promoter	DNA-directed RNA polymerase III subunit RPC10 DNA-directed RNA polymerase III subunit RPC1 DNA-directed RNA polymerase III subunit RPC2 DNA-directed RNA polymerase III subunit RPC3 DNA-directed RNA polymerase III subunit RPC4 DNA-directed RNA polymerase III subunit RPC5 DNA-directed RNA polymerase III subunit RPC6 DNA-directed RNA polymerase III subunit RPC7-like DNA-directed RNA polymerase III subunit RPC7 DNA-directed RNA polymerase III subunit RPC8 DNA-directed RNA polymerase III subunit RPC9 DNA-directed RNA polymerases I and III subunit RPAC1 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 POU domain, class 2, transcription factor 1 Protein POLR1D, isoform 2 TATA-box-binding protein Transcription factor IIIB 50 kDa subunit Transcription factor TFIIIB component B'' homolog Zinc finger protein 143 snRNA-activating protein complex subunit 1 snRNA-activating protein complex subunit 2 snRNA-activating protein complex subunit 3 snRNA-activating protein complex subunit 4 snRNA-activating protein complex subunit 5	A6H8Y1 O14802 O15160 O15318 O75575 O75971 P05423 P0DPB5 P14859 P19388 P20226 P52434 P52747 P53803 P61218 P62875 Q13487 Q16533 Q5SXM2 Q92966 Q9BT43 Q9BUI4 Q9H1D9 Q9HAW0 Q9NVU0 Q9NW08 Q9Y2Y1 Q9Y535	BDP1 BN51 BN51T BRF2 BRFU CRCP GTF2D1 KIAA1241 KIAA1452 KIAA1665 KIAA1689 OCT1 OTF1 POLR1C POLR1D POLR1E POLR2E POLR2F POLR2H POLR2K POLR2L POLR3A POLR3B POLR3C POLR3D POLR3E POLR3F POLR3G POLR3GL POLR3H POLR3K POLRF POU2F1 RPC11 RPC8 SBF SNAP19 SNAP190 SNAP43 SNAP45 SNAP50 SNAPC1 SNAPC2 SNAPC3 SNAPC4 SNAPC5 STAF TBP TF2D TFIID TFNR ZNF143
AXIN missense mutants destabilize the destruction complex	APC membrane recruitment protein 1 Adenomatous polyposis coli protein Axin-1 Casein kinase I isoform alpha Glycogen synthase kinase-3 beta Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform	O15169 P25054 P30153 P30154 P48729 P49841 P62714 P67775 Q13362 Q14738 Q15172 Q15173 Q16537 Q5JTC6	AMER1 APC AXIN AXIN1 CSNK1A1 DP2.5 FAM123B GSK3B KIAA0044 PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E WTX
Opioid Signalling	Mu-type opioid receptor Pro-opiomelanocortin Proenkephalin-B	P01189 P01213 P35372	MOR1 OPRM1 PDYN POMC
VEGFA-VEGFR2 Pathway	Abl interactor 1 Abl interactor 2 Actin-binding protein WASF1 Actin-binding protein WASF2 Actin-binding protein WASF3 Adapter molecule crk BAR/IMD domain-containing adapter protein 2 Breast cancer anti-estrogen resistance protein 1 Cell division control protein 42 homolog Cytochrome b-245 heavy chain Cytochrome b-245 light chain Cytoplasmic FMR1-interacting protein 1 Cytoplasmic FMR1-interacting protein 2 Cytoplasmic protein NCK2 Dedicator of cytokinesis protein 1 Engulfment and cell motility protein 1 Engulfment and cell motility protein 2 Focal adhesion kinase 1 Guanine nucleotide exchange factor VAV2 Guanine nucleotide exchange factor VAV3 Heat shock protein HSP 90-alpha Heat shock protein beta-1 Integrin alpha-V Integrin beta-3 MAP kinase-activated protein kinase 2 MAP kinase-activated protein kinase 3 Mitogen-activated protein kinase 11 Mitogen-activated protein kinase 12 Mitogen-activated protein kinase 13 Mitogen-activated protein kinase 14 Nck-associated protein 1-like Nck-associated protein 1 Neutrophil cytosol factor 1 Neutrophil cytosol factor 2 Neutrophil cytosol factor 4 Paxillin Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Protein BRICK1 Protein-tyrosine kinase 2-beta Proto-oncogene vav Ras-related C3 botulinum toxin substrate 1 Rho-associated protein kinase 1 Rho-associated protein kinase 2 SH2 domain-containing adapter protein B SH2 domain-containing protein 2A SH2/SH3 adapter protein NCK1 SHC-transforming protein 2 Serine/threonine-protein kinase PAK 2 Transforming protein RhoA Tyrosine-protein kinase Fyn Tyrosine-protein kinase receptor UFO Vascular endothelial growth factor receptor 2 cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit gamma	O00459 O15264 O43639 O75116 P04792 P04839 P05106 P06241 P06756 P07900 P13498 P14598 P15498 P16333 P17612 P19878 P22612 P22694 P27986 P30530 P35968 P42336 P42338 P46108 P49023 P49137 P52735 P53778 P55160 P56945 P60953 P61586 P63000 P98077 Q05397 Q13177 Q13464 Q14185 Q14289 Q15080 Q15464 Q15759 Q16539 Q16644 Q7L576 Q8IZP0 Q8WUW1 Q92556 Q92558 Q96F07 Q96JJ3 Q9NP31 Q9NYB9 Q9UKW4 Q9UPY6 Q9UQB8 Q9Y2A7 Q9Y6W5	ABI1 ABI2 ARGBPIA ARH12 ARHA AXL BAIAP2 BCAR1 BRK1 C3orf10 CAS CASS1 CDC42 CED12A CRK CRKAS CSBP CSBP1 CSBP2 CSPB1 CYBA CYBB CYFIP1 CYFIP2 DOCK1 ELMO1 ELMO2 ERK6 FAK FAK1 FAK2 FLK1 FYN GP3A GRB1 GRB4 HEM1 HEM2 HSP27 HSP28 HSP90A HSP90AA1 HSPB1 HSPC1 HSPCA ITGAV ITGB3 KDR KIAA0068 KIAA0269 KIAA0281 KIAA0587 KIAA0619 KIAA0900 KIAA1168 KIAA1834 MAPK11 MAPK12 MAPK13 MAPK14 MAPKAPK2 MAPKAPK3 MSK8 MXI2 NAP1 NCF1 NCF2 NCF4 NCK NCK1 NCK2 NCKAP1 NCKAP1L NOX2 NOXA2 NOXO2 P67PHOX PAK2 PIK3C1 PIK3CA PIK3CB PIK3R1 PIK3R2 PIR121 PKACA PRKACA PRKACB PRKACG PRKM11 PRKM13 PTK2 PTK2B PXN PYK2 RAC1 RAFTK RHO12 RHOA ROCK1 ROCK2 SAPK2 SAPK2A SAPK2B SAPK3 SAPK4 SCAP SCAR1 SCAR3 SCK SH2D2A SH3PXD1A SH3PXD4 SHB SHC2 SHCB SSH3BP1 TC25 TSAD UFO VAV VAV1 VAV2 VAV3 VEGFR2 VNRA VRAP VTNR WASF1 WASF2 WASF3 WAVE1 WAVE2 WAVE3
Abasic sugar-phosphate removal via the single-nucleotide replacement pathway	DNA polymerase beta DNA repair nuclease/redox regulator APEX1	P06746 P27695	APE APE1 APEX APEX1 APX HAP1 POLB REF1
Toxicity of botulinum toxin type D (botD)	Botulinum neurotoxin type D Synaptic vesicle glycoprotein 2A Synaptic vesicle glycoprotein 2B Synaptic vesicle glycoprotein 2C Vesicle-associated membrane protein 1 Vesicle-associated membrane protein 2	P19321 P23763 P63027 Q496J9 Q7L0J3 Q7L1I2	KIAA0735 KIAA0736 KIAA1054 SV2A SV2B SV2C SYB1 SYB2 VAMP1 VAMP2 botD
Macroautophagy	5'-AMP-activated protein kinase catalytic subunit alpha-1 5'-AMP-activated protein kinase catalytic subunit alpha-2 5'-AMP-activated protein kinase subunit beta-1 5'-AMP-activated protein kinase subunit beta-2 5'-AMP-activated protein kinase subunit gamma-1 5'-AMP-activated protein kinase subunit gamma-2 5'-AMP-activated protein kinase subunit gamma-3 Activating molecule in BECN1-regulated autophagy protein 1 Autophagy protein 5 Autophagy-related protein 101 Autophagy-related protein 13 Autophagy-related protein 16-1 Autophagy-related protein 9A Autophagy-related protein 9B Beclin 1-associated autophagy-related key regulator Beclin-1 Charged multivesicular body protein 2a Charged multivesicular body protein 2b Charged multivesicular body protein 3 Charged multivesicular body protein 4a Charged multivesicular body protein 4b Charged multivesicular body protein 4c Charged multivesicular body protein 6 Charged multivesicular body protein 7 Cysteine protease ATG4A Cysteine protease ATG4B Cysteine protease ATG4C Cysteine protease ATG4D Dynein light chain 1, cytoplasmic Dynein light chain 2, cytoplasmic GTP-binding protein Rheb Gamma-aminobutyric acid receptor-associated protein-like 1 Gamma-aminobutyric acid receptor-associated protein-like 2 Gamma-aminobutyric acid receptor-associated protein-like 3 Gamma-aminobutyric acid receptor-associated protein Hamartin Microtubule-associated proteins 1A/1B light chain 3A Microtubule-associated proteins 1A/1B light chain 3B Microtubule-associated proteins 1A/1B light chain 3C Neutral amino acid transporter 9 Phosphatidylinositol 3-kinase catalytic subunit type 3 Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR14 Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR3 Phosphoinositide 3-kinase regulatory subunit 4 RB1-inducible coiled-coil protein 1 Ragulator complex protein LAMTOR1 Ragulator complex protein LAMTOR2 Ragulator complex protein LAMTOR3 Ragulator complex protein LAMTOR4 Ragulator complex protein LAMTOR5 Ras-related GTP-binding protein A Ras-related GTP-binding protein B Ras-related GTP-binding protein C Ras-related GTP-binding protein D Regulatory-associated protein of mTOR Serine/threonine-protein kinase ULK1 Serine/threonine-protein kinase mTOR Target of rapamycin complex subunit LST8 Tuberin UV radiation resistance-associated gene protein Ubiquitin-like modifier-activating enzyme ATG7 Ubiquitin-like protein ATG12 Ubiquitin-like-conjugating enzyme ATG10 Ubiquitin-like-conjugating enzyme ATG3 WD repeat domain phosphoinositide-interacting protein 1 WD repeat domain phosphoinositide-interacting protein 2 WD repeat domain phosphoinositide-interacting protein 3 WD repeat domain phosphoinositide-interacting protein 4	O43504 O43633 O43741 O75143 O75385 O94817 O95166 O95352 P42345 P49815 P54619 P54646 P60520 P63167 Q0VGL1 Q13131 Q13615 Q14457 Q15382 Q5MNZ6 Q5MNZ9 Q5VZM2 Q674R7 Q676U5 Q6IAA8 Q6ZNE5 Q7L523 Q7Z3C6 Q86TL0 Q8N122 Q8NBW4 Q8NCE2 Q8NEB9 Q8TDY2 Q8WUX9 Q8WYN0 Q92574 Q96CF2 Q96DT6 Q96FJ2 Q96FZ7 Q99570 Q9BSB4 Q9BVC4 Q9BXW4 Q9BY43 Q9BY60 Q9C0C7 Q9GZQ8 Q9H0R8 Q9H0Y0 Q9H1Y0 Q9H444 Q9H492 Q9HB90 Q9NQL2 Q9NT62 Q9P2Y5 Q9UGI9 Q9UGJ0 Q9UHA4 Q9UQN3 Q9Y2Q5 Q9Y3E7 Q9Y478 Q9Y484 Q9Y4P1 Q9Y4P8	AMBRA1 AMPK AMPK1 AMPK2 AMPKG3 APG10L APG12 APG12L APG16L APG3 APG3L APG4A APG4B APG4C APG4D APG5L APG7L APG9L1 APG9L2 ASP ATG10 ATG101 ATG12 ATG13 ATG14 ATG14L ATG16L1 ATG3 ATG4A ATG4B ATG4C ATG4D ATG5 ATG7 ATG9A ATG9B AUTL1 AUTL2 AUTL3 AUTL4 BC2 BECN1 C11orf59 C12orf44 C14orf123 C20orf178 C3orf29 C7orf59 CGI149 CHMP2 CHMP2A CHMP2B CHMP3 CHMP4A CHMP4B CHMP4C CHMP6 CHMP7 DCAF3 DLC1 DLC2 DNCL1 DNCLC1 DYNLL1 DYNLL2 FLC3A FLC3B FRAP FRAP1 FRAP2 GABARAP GABARAPL1 GABARAPL2 GABARAPL3 GBL GEC1 GEF2 GT197 HBXIP HDLC1 KIAA0203 KIAA0243 KIAA0371 KIAA0652 KIAA0722 KIAA0831 KIAA0943 KIAA1303 KIAA1736 LAMTOR1 LAMTOR2 LAMTOR3 LAMTOR4 LAMTOR5 LST8 MAP1ALC3 MAP1LC3A MAP1LC3B MAP1LC3C MAP2K1IP1 MAPBPIP MAPKSP1 MLST8 MTMR14 MTMR3 MTOR NEDF NOS3AS PDRO PIK3C3 PIK3R4 PRKAA1 PRKAA2 PRKAB1 PRKAB2 PRKAG1 PRKAG2 PRKAG3 RAFT1 RAPT1 RAPTOR RB1CC1 RBICC RHEB RHEB2 ROBLD3 RPTOR RRAGA RRAGB RRAGC RRAGD SHAX1 SHAX2 SHAX3 SLC38A9 TSC TSC1 TSC2 TSC4 ULK1 URLC11 UVRAG VPS15 VPS20 VPS24 VPS34 WDR45 WDR45B WDR45L WDRX1 WDRXI4 WIPI1 WIPI2 WIPI3 WIPI4 WIPI49 XIP ZFYVE10
Resistance of ERBB2 KD mutants to osimertinib	Erbin Heat shock protein HSP 90-alpha Hsp90 co-chaperone Cdc37 Receptor tyrosine-protein kinase erbB-2	P04626 P07900 Q16543 Q96RT1	CDC37 CDC37A ERBB2 ERBB2IP ERBIN HER2 HSP90A HSP90AA1 HSPC1 HSPCA KIAA1225 LAP2 MLN19 NEU NGL
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models	14-3-3 protein epsilon Amyloid-beta precursor protein Bcl-2-like protein 11 Calpain small subunit 1 Calpain small subunit 2 Calpain-1 catalytic subunit Calpain-2 catalytic subunit Calpastatin Cyclin-dependent kinase 5 activator 1 Cyclin-dependent kinase 5 Forkhead box protein O3 Golgin subfamily A member 2 Lamin-B1 M-phase inducer phosphatase 1 M-phase inducer phosphatase 2 M-phase inducer phosphatase 3 Peroxiredoxin-1 Peroxiredoxin-2 Superoxide dismutase [Mn], mitochondrial Transcription factor Jun Tumor necrosis factor ligand superfamily member 6	O43521 O43524 P04179 P04632 P05067 P05412 P07384 P17655 P20700 P20810 P30304 P30305 P30307 P32119 P48023 P62258 Q00535 Q06830 Q08379 Q15078 Q96L46	A4 AD1 APP APT1LG1 BCL2L11 BIM CANPL1 CANPL2 CAPN1 CAPN2 CAPN4 CAPNS CAPNS1 CAPNS2 CAST CD95L CDC25A CDC25B CDC25C CDC25HU2 CDK5 CDK5R CDK5R1 CDKN5 FASL FASLG FKHRL1 FOXO3 FOXO3A GOLGA2 JUN LMN2 LMNB LMNB1 NCK5A NKEFB PAGA PAGB PRDX1 PRDX2 PSSALRE SOD2 TDPX1 TDPX2 TNFSF6 YWHAE
Loss-of-function mutations in DBT cause MSUD2	2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial Dihydrolipoyl dehydrogenase, mitochondrial Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial	P09622 P11182 P12694 P21953	BCATE2 BCKDHA BCKDHB BCKDHE2 DBT DLD GCSL LAD PHE3
PINK1-PRKN Mediated Mitophagy	Autophagy protein 5 Autophagy-related protein 9A E3 ubiquitin-protein ligase parkin Microtubule-associated proteins 1A/1B light chain 3A Microtubule-associated proteins 1A/1B light chain 3B Mitochondrial import receptor subunit TOM20 homolog Mitochondrial import receptor subunit TOM22 homolog Mitochondrial import receptor subunit TOM40 homolog Mitochondrial import receptor subunit TOM5 homolog Mitochondrial import receptor subunit TOM6 homolog Mitochondrial import receptor subunit TOM7 homolog Mitochondrial import receptor subunit TOM70 Mitofusin-1 Mitofusin-2 Non-selective voltage-gated ion channel VDAC1 Optineurin Polyubiquitin-B Polyubiquitin-C Sequestosome-1 Serine/threonine-protein kinase PINK1, mitochondrial Serine/threonine-protein kinase TBK1 Transcription termination factor 3, mitochondrial Ubiquitin-conjugating enzyme E2 D2 Ubiquitin-conjugating enzyme E2 D3 Ubiquitin-conjugating enzyme E2 L3 Ubiquitin-conjugating enzyme E2 N Ubiquitin-conjugating enzyme E2 variant 1 Ubiquitin-like protein ATG12 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Voltage-dependent anion-selective channel protein 2 Voltage-dependent anion-selective channel protein 3	O60260 O94817 O94826 O95140 O96008 P0CG47 P0CG48 P21796 P45880 P61077 P61088 P62837 P62979 P62987 P68036 Q13404 Q13501 Q15388 Q7Z3C6 Q8IWA4 Q8N4H5 Q96B49 Q96CV9 Q96E29 Q9BXM7 Q9GZQ8 Q9H1Y0 Q9H492 Q9NS69 Q9P0U1 Q9UHD2 Q9Y277	APG12 APG12L APG5L APG9L1 ASP ATG12 ATG5 ATG9A BLU C19orf1 C9orf105 CPRP1 CROC1 FIP2 GLC1E HIP7 HYPL KIAA0016 KIAA0214 KIAA0719 MAP1ALC3 MAP1LC3A MAP1LC3B MFN1 MFN2 MTERF3 MTERFD1 NAK NRP OBTP OPTN ORCA OSIL PARK2 PEREC1 PINK1 PRKN PUBC1 RPS27A SQSTM1 TBK1 TOM22 TOM40 TOM5 TOM6 TOM7 TOM70 TOMM07 TOMM20 TOMM22 TOMM40 TOMM5 TOMM6 TOMM7 TOMM70 TOMM70A UBA52 UBA80 UBB UBC UBC4 UBC5B UBC5C UBCE7 UBCEP1 UBCEP2 UBCH4 UBCH5B UBCH5C UBCH7 UBE2D2 UBE2D3 UBE2L3 UBE2N UBE2V UBE2V1 UEV1 VDAC VDAC1 VDAC2 VDAC3
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection	CDK-activating kinase assembly factor MAT1 Cyclin-H Cyclin-dependent kinase 7 DNA-directed RNA polymerase II subunit RPB11-a DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 General transcription and DNA repair factor IIH helicase subunit XPD General transcription and DNA repair factor IIH helicase/translocase subunit XPB General transcription factor IIF subunit 1 General transcription factor IIF subunit 2 General transcription factor IIH subunit 1 General transcription factor IIH subunit 2 General transcription factor IIH subunit 3 General transcription factor IIH subunit 4 General transcription factor IIH subunit 5 Transcription elongation factor SPT5 mRNA cap guanine-N7 methyltransferase mRNA-capping enzyme	O00267 O15514 O43148 O60942 P13984 P18074 P19387 P19388 P19447 P24928 P30876 P32780 P35269 P36954 P50613 P51946 P51948 P52434 P52435 P53803 P61218 P62487 P62875 Q13888 Q13889 Q6ZYL4 Q92759	BTF2 BTF2P44 C6orf175 CAK CAK1 CAP1A CAP35 CCNH CDK7 CDKN7 ERCC2 ERCC3 GTF2F1 GTF2F2 GTF2H1 GTF2H2 GTF2H3 GTF2H4 GTF2H5 KIAA0398 MAT1 MNAT1 MO15 POLR2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J1 POLR2K POLR2L POLRF RAP30 RAP74 RNF66 RNGTT RNMT RPB7 SPT5 SPT5H STK1 SUPT5H TTDA XPB XPBC XPD XPDC
Defective ABCA3 causes SMDP3	Phospholipid-transporting ATPase ABCA3	Q99758	ABC3 ABCA3
Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7	Inhibitor of nuclear factor kappa-B kinase subunit epsilon Lymphocyte antigen 96 Monocyte differentiation antigen CD14 Optineurin Polyubiquitin-B Polyubiquitin-C Serine/threonine-protein kinase TBK1 TIR domain-containing adapter molecule 1 TIR domain-containing adapter molecule 2 TNF receptor-associated factor 3 TRAF family member-associated NF-kappa-B activator Toll-like receptor 4 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00206 P08571 P0CG47 P0CG48 P62979 P62987 Q13114 Q14164 Q86XR7 Q8IUC6 Q92844 Q96CV9 Q9UHD2 Q9Y6Y9	CAP-1 CD14 CRAF1 ESOP1 FIP2 GLC1E HIP7 HYPL IKBKE IKKE IKKI ITRAF KIAA0151 LY96 MD2 NAK NRP OPTN PRVTIRB RPS27A TANK TBK1 TICAM1 TICAM2 TIRAP3 TIRP TLR4 TRAF2 TRAF3 TRAFAMN TRAM TRIF UBA52 UBA80 UBB UBC UBCEP1 UBCEP2
Acetylcholine Neurotransmitter Release Cycle	Choline O-acetyltransferase Complexin-1 High affinity choline transporter 1 Liprin-alpha-1 Liprin-alpha-2 Liprin-alpha-3 Liprin-alpha-4 Peripheral-type benzodiazepine receptor-associated protein 1 Protein unc-13 homolog B Ras-related protein Rab-3A Regulating synaptic membrane exocytosis protein 1 Synaptosomal-associated protein 25 Synaptotagmin-1 Syntaxin-1A Vesicle-associated membrane protein 2 Vesicular acetylcholine transporter	O14795 O14810 O75145 O75334 O75335 O95153 P20336 P21579 P28329 P60880 P63027 Q13136 Q16572 Q16623 Q86UR5 Q9GZV3	BZRAP1 CHAT CHT1 CPLX1 KIAA0340 KIAA0612 KIAA0654 KIAA0897 LIP1 PPFIA1 PPFIA2 PPFIA3 PPFIA4 RAB3A RAB3IP2 RBP1 RIM1 RIMBP1 RIMS1 SLC18A3 SLC5A7 SNAP SNAP25 STX1 STX1A SVP65 SYB2 SYT SYT1 TSPOAP1 UNC13 UNC13B VACHT VAMP2
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Cullin-1 E3 ubiquitin-protein ligase RBX1 F-box/WD repeat-containing protein 1A Glycogen synthase kinase-3 beta Nuclear factor erythroid 2-related factor 2 Polyubiquitin-B Polyubiquitin-C Proteasomal ubiquitin receptor ADRM1 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 S-phase kinase-associated protein 1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00231 O00232 O00487 O14818 O43242 P0CG47 P0CG48 P17980 P20618 P25786 P25787 P25788 P25789 P28066 P28070 P28072 P28074 P35998 P43686 P48556 P49720 P49721 P49841 P51665 P60896 P60900 P62191 P62195 P62333 P62877 P62979 P62987 P63208 Q13200 Q13616 Q15008 Q16186 Q16236 Q99436 Q99460 Q9UNM6 Q9Y297	ADRM1 BTRC BTRCP C7orf76 CUL1 DSS1 EMC19 FBW1A FBXW1A GP110 GSK3B HC2 HC3 HC8 HC9 HSPC KIAA0107 LMPX LMPY MB1 MIP224 MOV34L MSS1 NFE2L2 NRF2 NU OCP2 PFAAP4 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PSMD8 RBX1 RNF75 ROC1 RPS27A SEM1 SHFDG1 SHFM1 SKP1 SKP1A SUG1 SUG2 TBP1 TBP7 TCEB1L TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 X Y Z
Defective F9 activation	Coagulation factor IX Coagulation factor XI Platelet glycoprotein IX Platelet glycoprotein Ib alpha chain Platelet glycoprotein Ib beta chain Platelet glycoprotein V	P00740 P03951 P07359 P13224 P14770 P40197	F11 F9 GP1BA GP1BB GP5 GP9
Stabilization of p53	Cellular tumor antigen p53 E3 ubiquitin-protein ligase Mdm2 PHD finger protein 20 Polyubiquitin-B Polyubiquitin-C Protein Mdm4 Serine-protein kinase ATM Serine/threonine-protein kinase Chk2 Tumor suppressor ARF Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O15151 O96017 P04637 P0CG47 P0CG48 P62979 P62987 Q00987 Q13315 Q8N726 Q9BVI0	ATM C20orf104 CDKN2 CDKN2A CDS1 CHEK2 CHK2 GLEA2 HCA58 MDM2 MDM4 MDMX MLM NZF P53 PHF20 RAD53 RPS27A TP53 TZP UBA52 UBA80 UBB UBC UBCEP1 UBCEP2
MAP3K8 (TPL2)-dependent MAPK1/3 activation	Cullin-1 Dual specificity mitogen-activated protein kinase kinase 1 Dual specificity mitogen-activated protein kinase kinase 4 F-box/WD repeat-containing protein 11 F-box/WD repeat-containing protein 1A Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Mitogen-activated protein kinase kinase kinase 8 NF-kappa-B essential modulator Nuclear factor NF-kappa-B p105 subunit Polyubiquitin-B Polyubiquitin-C S-phase kinase-associated protein 1 TNFAIP3-interacting protein 2 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O14920 O15111 P0CG47 P0CG48 P19838 P41279 P45985 P62979 P62987 P63208 Q02750 Q13616 Q8NFZ5 Q9UKB1 Q9Y297 Q9Y6K9	ABIN2 BTRC BTRCP BTRCP2 CHUK COT CUL1 EMC19 ESTF FBW1A FBW1B FBXW11 FBXW1A FBXW1B FIP3 FLIP1 IKBKB IKBKG IKKA IKKB JNKK1 KIAA0696 MAP2K1 MAP2K4 MAP3K8 MEK1 MEK4 MKK4 NEMO NFKB1 OCP2 PRKMK1 PRKMK4 RPS27A SEK1 SERK1 SKK1 SKP1 SKP1A TCEB1L TCF16 TNIP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2
TFAP2 (AP-2) family regulates transcription of cell cycle factors	Cyclin-dependent kinase inhibitor 1 Lysine-specific demethylase 5B Myc proto-oncogene protein Transcription factor AP-2 gamma Transcription factor AP-2-alpha	P01106 P05549 P38936 Q92754 Q9UGL1	AP2TF BHLHE39 CAP20 CDKN1 CDKN1A CIP1 JARID1B KDM5B MDA6 MYC PIC1 PLU1 RBBP2H1 SDI1 TFAP2 TFAP2A TFAP2C WAF1
RHOT1 GTPase cycle	Mitochondrial Rho GTPase 1 Rap1 GTPase-GDP dissociation stimulator 1 Trafficking kinesin-binding protein 1 Trafficking kinesin-binding protein 2 Unconventional myosin-XIX	O60296 P52306 Q8IXI2 Q96H55 Q9UPV9	ALS2CR3 ARHT1 KIAA0549 KIAA1042 MYO19 MYOHD1 OIP106 RAP1GDS1 RHOT1 SMGGDS TRAK1 TRAK2
Collagen degradation	5-phosphohydroxy-L-lysine phospho-lyase 72 kDa type IV collagenase Cathepsin B Cathepsin D Cathepsin K Collagen alpha-1(IX) chain Collagen alpha-1(XII) chain Collagen alpha-1(XIII) chain Collagen alpha-1(XIV) chain Collagen alpha-1(XIX) chain Collagen alpha-1(XV) chain Collagen alpha-1(XVI) chain Collagen alpha-1(XVII) chain Collagen alpha-1(XVIII) chain Collagen alpha-1(XXIII) chain Collagen alpha-1(XXV) chain Collagen alpha-1(XXVI) chain Collagen alpha-2(IX) chain Collagen alpha-3(IX) chain Collagenase 3 Disintegrin and metalloproteinase domain-containing protein 10 Disintegrin and metalloproteinase domain-containing protein 17 Disintegrin and metalloproteinase domain-containing protein 9 Furin Interstitial collagenase Macrophage metalloelastase Matrilysin Matrix metalloproteinase-14 Matrix metalloproteinase-15 Matrix metalloproteinase-19 Matrix metalloproteinase-20 Matrix metalloproteinase-9 Neutrophil collagenase Neutrophil elastase Procathepsin L Stromelysin-1 Stromelysin-2 Stromelysin-3 Transmembrane protease serine 6 Trypsin-2	O14672 O60882 P03956 P07339 P07478 P07711 P07858 P08246 P08253 P08254 P09237 P09238 P09958 P14780 P20849 P22894 P24347 P39059 P39060 P39900 P43235 P45452 P50281 P51511 P78536 Q05707 Q07092 Q13443 Q14050 Q14055 Q14993 Q5TAT6 Q86Y22 Q8IU80 Q8IUZ5 Q96A83 Q99542 Q99715 Q9BXS0 Q9UMD9	ADAM10 ADAM17 ADAM9 AGXT2L2 BP180 BPAG2 CLG CLG1 CLG4A CLG4B COL12A1 COL12A1L COL13A1 COL14A1 COL15A1 COL16A1 COL17A1 COL18A1 COL19A1 COL23A1 COL25A1 COL26A1 COL9A1 COL9A2 COL9A3 CPSB CPSD CSVP CTSB CTSD CTSK CTSL CTSL1 CTSO CTSO2 ELA2 ELANE EMID2 EMU2 FUR FURIN HME KIAA0021 KUZ MADM MCMP MDC9 MLTNG MMP1 MMP10 MMP11 MMP12 MMP13 MMP14 MMP15 MMP18 MMP19 MMP2 MMP20 MMP3 MMP7 MMP8 MMP9 MPSL1 PACE PCSK3 PHYKPL PRSS2 PUMP1 RASI STMY1 STMY2 STMY3 TACE TMPRSS6 TRY2 TRYP2 UND
Propionyl-CoA catabolism	Methylmalonic aciduria type A protein, mitochondrial Methylmalonyl-CoA epimerase, mitochondrial Methylmalonyl-CoA mutase, mitochondrial Propionyl-CoA carboxylase alpha chain, mitochondrial Propionyl-CoA carboxylase beta chain, mitochondrial	P05165 P05166 P22033 Q8IVH4 Q96PE7	MCEE MMAA MMUT MUT PCCA PCCB

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