TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P
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TBC/RABGAPs
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- ARF6
- C20orf140
- EPI64
- FIP2
- FLC3A
- FLC3B
- GABARAP
- GABARAPL2
- GEF2
- GGA1
- GGA2
- GGA3
- GLC1E
- HIP7
- HYPL
- KIAA0154
- KIAA0243
- KIAA0722
- KIAA1080
- KIAA1171
- KIAA1322
- MAP1ALC3
- MAP1LC3B
- MEL
- NRP
- OATL1
- OPTN
- PARIS1
- PP8997
- PRC17
- RAB11
- RAB11A
- RAB11B
- RAB1C
- RAB33A
- RAB33B
- RAB35
- RAB4
- RAB4A
- RAB5
- RAB5A
- RAB5B
- RAB5C
- RAB5EP
- RAB6
- RAB6A
- RAB6B
- RAB7
- RAB7A
- RAB7B
- RAB8
- RAB8A
- RAB8B
- RABEP1
- RABEX5
- RABGAP1
- RABGEF1
- RABL
- RABPT5
- RABPT5A
- RABS10
- RAY
- SLP1
- SYTL1
- TBC1D10
- TBC1D10A
- TBC1D10B
- TBC1D10C
- TBC1D13
- TBC1D14
- TBC1D15
- TBC1D16
- TBC1D17
- TBC1D2
- TBC1D20
- TBC1D24
- TBC1D25
- TBC1D2A
- TBC1D3
- TBC1D3A
- TBC1D7
- TBC7
- TSC
- TSC1
- TSC2
- TSC4
- ULK1
- YPT3
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TCF dependent signaling in response to WNT
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- AXIN
- AXIN1
- AXIN2
- CTNNB
- CTNNB1
- DKK1
- DKK2
- DKK4
- DVL1
- DVL2
- DVL3
- FRP
- FRP1
- FRP2
- FZD1
- FZD2
- INT1
- INT4
- JTK5A
- KIAA0208
- KIAA0570
- KIAA0729
- KREMEN
- KREMEN1
- KREMEN2
- KRM1
- KRM2
- LR3
- LRP5
- LRP6
- LRP7
- PARP5A
- PARP5B
- PARPL
- RNF146
- RPS27A
- RYK
- SARP1
- SARP2
- SFRP1
- SFRP2
- SOST
- TANK2
- TIN1
- TINF1
- TNKL
- TNKS
- TNKS1
- TNKS2
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
- USP34
- WIF1
- WNT1
- WNT14
- WNT3
- WNT3A
- WNT4
- WNT5A
- WNT8A
- WNT8B
- WNT8D
- WNT9A
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TFAP2 (AP-2) family regulates transcription of cell cycle factors
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- AP2TF
- BHLHE39
- CAP20
- CDKN1
- CDKN1A
- CIP1
- JARID1B
- KDM5B
- MDA6
- MYC
- PIC1
- PLU1
- RBBP2H1
- SDI1
- TFAP2
- TFAP2A
- TFAP2C
- WAF1
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TFAP2 (AP-2) family regulates transcription of growth factors and their receptors
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- AP2TF
- ATAD2
- CGA
- CGB
- CGB3
- CGB5
- CGB8
- EGFR
- ERBB
- ERBB1
- ERBB2
- ESR
- ESR1
- HER1
- HER2
- INO80S
- KIT
- MLN19
- NEU
- NGL
- NR3A1
- SCFR
- TFAP2
- TFAP2A
- TFAP2B
- TFAP2C
- TGFA
- VEGF
- VEGFA
- YY1
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TFAP2 (AP-2) family regulates transcription of other transcription factors
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- AP2TF
- ARP1
- CITED2
- MRG1
- PITX2
- RGS
- RIEG
- RIEG1
- TFAP2
- TFAP2A
- TFAP2C
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TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation
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- AP2TF
- BMYB
- HSP60
- HSPD1
- MYBL2
- NOL1
- NOP2
- NPM
- NPM1
- NSUN1
- TFAP2
- TFAP2A
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TGF-beta receptor signaling activates SMADs
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- ALK5
- C14orf141
- CBL
- CBL2
- DPC4
- FKBP1
- FKBP12
- FKBP1A
- FNRB
- FUR
- FURIN
- GP3A
- ITGA8
- ITGAV
- ITGB1
- ITGB3
- ITGB5
- ITGB6
- ITGB8
- LTBP1
- LTBP2
- LTBP3
- LTBP4
- MADH2
- MADH3
- MADH4
- MADR2
- MDF2
- MSK12
- MSK8
- NEDD8
- PACE
- PCSK3
- RNF55
- SKR4
- SMAD2
- SMAD3
- SMAD4
- TGFB
- TGFB1
- TGFB2
- TGFB3
- TGFBR1
- TGFBR2
- TGFBR3
- UBC12
- UBE2M
- VNRA
- VTNR
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TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
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- ALK5
- ARH12
- ARHA
- ARHGEF18
- CGN
- F11R
- FKBP1
- FKBP12
- FKBP1A
- JAM1
- JCAM
- KIAA0521
- KIAA1319
- KIAA1625
- PAR3
- PAR3A
- PAR6A
- PARD3
- PARD6A
- PKC2
- PRKCZ
- RHO12
- RHOA
- RPS27A
- SKR4
- SMURF1
- TGFB
- TGFB1
- TGFBR1
- TGFBR2
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
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TGFBR1 KD Mutants in Cancer
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- ALK5
- MADH2
- MADH3
- MADR2
- SKR4
- SMAD2
- SMAD3
- TGFB
- TGFB1
- TGFBR1
- TGFBR2
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TGFBR1 LBD Mutants in Cancer
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- ALK5
- FKBP1
- FKBP12
- FKBP1A
- SKR4
- TGFB
- TGFB1
- TGFBR1
- TGFBR2
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TGFBR2 Kinase Domain Mutants in Cancer
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- ALK5
- SKR4
- TGFB
- TGFB1
- TGFBR1
- TGFBR2
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TGFBR2 MSI Frameshift Mutants in Cancer
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TICAM1 deficiency - HSE
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TICAM1, RIP1-mediated IKK complex recruitment
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- API1
- API2
- BIRC2
- BIRC3
- BLU
- CHUK
- CROC1
- FIP3
- IKBKB
- IKBKG
- IKKA
- IKKB
- MIHB
- MIHC
- NEMO
- PRVTIRB
- PUBC1
- RIP
- RIP1
- RIP3
- RIPK1
- RIPK3
- RNF48
- RNF49
- RNF85
- RPS27A
- SFT
- TCF16
- TICAM1
- TLR3
- TRAF6
- TRIF
- UBA52
- UBA80
- UBB
- UBC
- UBC4
- UBC5A
- UBC5B
- UBC5C
- UBCEP1
- UBCEP2
- UBCH4
- UBCH5
- UBCH5A
- UBCH5B
- UBCH5C
- UBE2D1
- UBE2D2
- UBE2D3
- UBE2N
- UBE2V
- UBE2V1
- UEV1
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TICAM1,TRAF6-dependent induction of TAK1 complex
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- KIAA0733
- MAP3K7
- MAP3K7IP1
- MAP3K7IP2
- MAP3K7IP3
- PRVTIRB
- RNF85
- RPS27A
- TAB1
- TAB2
- TAB3
- TAK1
- TICAM1
- TLR3
- TRAF6
- TRIF
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
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TICAM1-dependent activation of IRF3/IRF7
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- CAP-1
- CRAF1
- FIP2
- GLC1E
- HIP7
- HYPL
- IKBKE
- IKKE
- IKKI
- IRF3
- IRF7
- ITRAF
- KIAA0151
- NAK
- NRP
- OPTN
- PRVTIRB
- RPS27A
- TANK
- TBK1
- TICAM1
- TLR3
- TRAF2
- TRAF3
- TRAFAMN
- TRIF
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
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TLR3 deficiency - HSE
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TLR3-mediated TICAM1-dependent programmed cell death
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- CASP8
- FADD
- MCH5
- MORT1
- PRVTIRB
- RIP
- RIP1
- RIP3
- RIPK1
- RIPK3
- TICAM1
- TLR3
- TRIF
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TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway
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- API1
- API2
- APO3L
- BAFF
- BAFFR
- BIRC2
- BIRC3
- BLYS
- BR3
- CAP-1
- CD40L
- CD40LG
- CRAF1
- D12S370
- DR3LG
- FN14
- HVEML
- LIGHT
- LTA
- LTB
- LTBR
- MAP3K14
- MIHB
- MIHC
- NIK
- OPGL
- RANK
- RANKL
- RNF48
- RNF49
- TALL1
- TNFB
- TNFC
- TNFCR
- TNFR3
- TNFRSF11A
- TNFRSF12A
- TNFRSF13C
- TNFRSF3
- TNFSF1
- TNFSF11
- TNFSF12
- TNFSF13B
- TNFSF14
- TNFSF20
- TNFSF3
- TNFSF5
- TRAF2
- TRAF3
- TRAFAMN
- TRANCE
- TRAP
- TRAP3
- ZTNF4
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TNF signaling
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- ADAM17
- BAG4
- CSVP
- RIP
- RIP1
- RIPK1
- SODD
- TACE
- TNF
- TNFA
- TNFAR
- TNFR1
- TNFRSF1A
- TNFSF2
- TRADD
- TRAF2
- TRAP3
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TNFR1-induced NF-kappa-B signaling pathway
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- API1
- API2
- API3
- BIRC2
- BIRC3
- BIRC4
- C20orf18
- CHUK
- CYLD
- CYLD1
- DUBA7
- EBI6
- FIP2
- FIP3
- GLC1E
- GNB2L1
- HIP7
- HYPL
- IAP3
- IKBKB
- IKBKG
- IKKA
- IKKB
- KIAA0733
- KIAA0757
- KIAA0849
- MAP3K7
- MAP3K7IP1
- MAP3K7IP2
- MAP3K7IP3
- MIHB
- MIHC
- NEMO
- NRP
- OPTN
- OTDC1
- OTUD1
- OTUD7B
- OTUD7C
- PD1
- RACK1
- RBCK1
- RIP
- RIP1
- RIPK1
- RNF31
- RNF48
- RNF49
- RNF54
- SHARPIN
- SIPL1
- SPATA2
- TAB1
- TAB2
- TAB3
- TAK1
- TCF16
- TNF
- TNFA
- TNFAIP3
- TNFAR
- TNFR1
- TNFRSF1A
- TNFSF2
- TRADD
- TRAF1
- TRAF2
- TRAP3
- UBCE7IP3
- UBP41
- UNP
- UNPH
- USP2
- USP21
- USP23
- USP4
- XAP3
- XAP4
- XIAP
- ZA20D1
- ZIBRA
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TNFR1-induced proapoptotic signaling
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- API1
- API2
- API3
- BIRC2
- BIRC3
- BIRC4
- C20orf18
- CASP8
- CYLD
- CYLD1
- DUBA7
- FADD
- FIP2
- GLC1E
- HIP7
- HYPL
- IAP3
- IKBKE
- IKKE
- IKKI
- KIAA0151
- KIAA0757
- KIAA0849
- MCH5
- MIB2
- MIHB
- MIHC
- MORT1
- NAK
- NRP
- OPTN
- OTDC1
- OTUD1
- OTUD7B
- OTUD7C
- PD1
- RBCK1
- RIP
- RIP1
- RIPK1
- RNF31
- RNF48
- RNF49
- RNF54
- SHARPIN
- SIPL1
- SKD
- SPATA2
- TBK1
- TNF
- TNFA
- TNFAIP3
- TNFAR
- TNFR1
- TNFRSF1A
- TNFSF2
- TRADD
- TRAF2
- TRAP3
- UBCE7IP3
- UBP41
- UL36
- UNP
- UNPH
- USP2
- USP21
- USP23
- USP4
- XAP3
- XAP4
- XIAP
- ZA20D1
- ZIBRA
- ZZANK1
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TNFR1-mediated ceramide production
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- FAN
- GNB2L1
- NSMAF
- RACK1
- SMPD2
- SMPD3
- TNF
- TNFA
- TNFAR
- TNFR1
- TNFRSF1A
- TNFSF2
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TNFR2 non-canonical NF-kB pathway
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- API1
- API2
- APO3L
- BAFF
- BAFFR
- BIRC2
- BIRC3
- BLYS
- BR3
- C7orf76
- CAP-1
- CD40L
- CD40LG
- CRAF1
- D12S370
- DR3LG
- DSS1
- FN14
- HC2
- HC3
- HC8
- HC9
- HSPC
- HVEML
- IFI5111
- KIAA0072
- KIAA0077
- KIAA0107
- LIGHT
- LMP10
- LMP2
- LMP7
- LMPX
- LMPY
- LTA
- LTB
- LTBR
- MAP3K14
- MB1
- MCB1
- MECL1
- MIHB
- MIHC
- MIP224
- MOV34L
- MSS1
- NIK
- NU
- OPGL
- PFAAP4
- POH1
- PROS26
- PROS27
- PROS30
- PSC2
- PSC3
- PSC5
- PSC8
- PSC9
- PSMA1
- PSMA2
- PSMA3
- PSMA4
- PSMA5
- PSMA6
- PSMA7
- PSMA7L
- PSMA8
- PSMB1
- PSMB10
- PSMB11
- PSMB2
- PSMB3
- PSMB4
- PSMB5
- PSMB5i
- PSMB6
- PSMB6i
- PSMB7
- PSMB8
- PSMB9
- PSMC1
- PSMC2
- PSMC3
- PSMC4
- PSMC5
- PSMC6
- PSMD1
- PSMD10
- PSMD11
- PSMD12
- PSMD13
- PSMD14
- PSMD2
- PSMD3
- PSMD4
- PSMD5
- PSMD6
- PSMD7
- PSMD8
- PSMD9
- PSME1
- PSME2
- PSME3
- PSME4
- PSMF1
- RANK
- RANKL
- RING10
- RING12
- RNF48
- RNF49
- SEM1
- SHFDG1
- SHFM1
- SUG1
- SUG2
- TALL1
- TBP1
- TBP7
- TNF
- TNFA
- TNFB
- TNFBR
- TNFC
- TNFCR
- TNFR2
- TNFR3
- TNFRSF11A
- TNFRSF12A
- TNFRSF13C
- TNFRSF1B
- TNFRSF3
- TNFSF1
- TNFSF11
- TNFSF12
- TNFSF13B
- TNFSF14
- TNFSF2
- TNFSF20
- TNFSF3
- TNFSF5
- TRAF2
- TRAF3
- TRAFAMN
- TRANCE
- TRAP
- TRAP2
- TRAP3
- X
- Y
- Y2
- Z
- ZTNF4
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