GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **1951 - 1975** of **2090** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism
ATP sensitive Potassium channels	ATP-binding cassette sub-family C member 8 ATP-binding cassette sub-family C member 9 ATP-sensitive inward rectifier potassium channel 11 ATP-sensitive inward rectifier potassium channel 8	O60706 Q09428 Q14654 Q15842	ABCC8 ABCC9 HRINS KCNJ11 KCNJ8 SUR SUR1 SUR2	Homo sapiens (human)
Eukaryotic Translation Elongation	Elongation factor 1-alpha 1 Elongation factor 1-alpha 2 Elongation factor 1-beta Elongation factor 1-delta Elongation factor 1-gamma Putative elongation factor 1-alpha-like 3	P24534 P26641 P29692 P68104 Q05639 Q5VTE0	EEF1A EEF1A1 EEF1A1P5 EEF1A2 EEF1AL EEF1AL3 EEF1B EEF1B2 EEF1D EEF1G EF1A EF1B EF1D EF1G LENG7 STN	Homo sapiens (human)
RPIA deficiency: failed conversion of RU5P to R5P	Ribose-5-phosphate isomerase	P49247	RPI RPIA	Homo sapiens (human)
MHC class II antigen presentation	ADP-ribosylation factor 1 AP-1 complex subunit beta-1 AP-1 complex subunit gamma-1 AP-1 complex subunit mu-1 AP-1 complex subunit mu-2 AP-1 complex subunit sigma-1A AP-1 complex subunit sigma-2 AP-1 complex subunit sigma-3 AP-2 complex subunit alpha-1 AP-2 complex subunit alpha-2 AP-2 complex subunit beta AP-2 complex subunit mu AP-2 complex subunit sigma Actin-related protein 10 Alpha-centractin Beta-centractin Calnexin Cathepsin B Cathepsin D Cathepsin E Cathepsin F Cathepsin K Cathepsin L2 Cathepsin O Cathepsin S Centromere-associated protein E Chromosome-associated kinesin KIF4A Chromosome-associated kinesin KIF4B Clathrin heavy chain 1 Clathrin light chain A Cytoplasmic dynein 1 heavy chain 1 Cytoplasmic dynein 1 intermediate chain 1 Cytoplasmic dynein 1 intermediate chain 2 Cytoplasmic dynein 1 light intermediate chain 1 Cytoplasmic dynein 1 light intermediate chain 2 Dipeptidyl peptidase 1 Dynactin subunit 1 Dynactin subunit 2 Dynactin subunit 3 Dynactin subunit 4 Dynactin subunit 5 Dynactin subunit 6 Dynamin-1 Dynamin-2 Dynamin-3 Dynein light chain 1, cytoplasmic Dynein light chain 2, cytoplasmic Endophilin-A1 F-actin-capping protein subunit alpha-1 F-actin-capping protein subunit alpha-2 F-actin-capping protein subunit alpha-3 F-actin-capping protein subunit beta Gamma-interferon-inducible lysosomal thiol reductase HLA class II histocompatibility antigen gamma chain HLA class II histocompatibility antigen, DM alpha chain HLA class II histocompatibility antigen, DM beta chain HLA class II histocompatibility antigen, DO alpha chain HLA class II histocompatibility antigen, DO beta chain HLA class II histocompatibility antigen, DP alpha 1 chain HLA class II histocompatibility antigen, DP beta 1 chain HLA class II histocompatibility antigen, DQ alpha 1 chain HLA class II histocompatibility antigen, DQ alpha 2 chain HLA class II histocompatibility antigen, DQ beta 1 chain HLA class II histocompatibility antigen, DQ beta 2 chain HLA class II histocompatibility antigen, DR alpha chain HLA class II histocompatibility antigen, DR beta 3 chain HLA class II histocompatibility antigen, DR beta 4 chain HLA class II histocompatibility antigen, DR beta 5 chain HLA class II histocompatibility antigen, DRB1 beta chain Kinesin heavy chain isoform 5A Kinesin light chain 1 Kinesin light chain 2 Kinesin light chain 3 Kinesin light chain 4 Kinesin-1 heavy chain Kinesin-associated protein 3 Kinesin-like protein (Fragment) Kinesin-like protein (Fragment) Kinesin-like protein KIF11 Kinesin-like protein KIF15 Kinesin-like protein KIF18A Kinesin-like protein KIF20A Kinesin-like protein KIF22 Kinesin-like protein KIF23 Kinesin-like protein KIF26A Kinesin-like protein KIF2A Kinesin-like protein KIF2B Kinesin-like protein KIF2C Kinesin-like protein KIF3A Kinesin-like protein KIF3B Kinesin-like protein KIF3C Legumain Lymphocyte activation gene 3 protein Lysosomal protective protein Oxysterol-binding protein-related protein 1 Pro-cathepsin H Procathepsin L Protein SEC13 homolog Protein transport protein Sec23A Protein transport protein Sec24A Protein transport protein Sec24B Protein transport protein Sec24C Protein transport protein Sec24D Protein transport protein Sec31A Rab-interacting lysosomal protein Rac GTPase-activating protein 1 Ras-related protein Rab-7a Small COPII coat GTPase SAR1B Spectrin beta chain, non-erythrocytic 2	O00139 O00399 O14576 O14782 O15020 O15066 O43237 O43747 O60911 O75935 O94855 O94973 O94979 O95235 O95239 O95486 O95487 O95782 P01903 P01906 P01909 P01911 P01920 P04233 P04440 P05538 P06340 P07339 P07711 P07858 P09496 P09668 P10619 P13284 P13762 P13765 P14091 P18627 P20036 P25774 P27824 P28067 P28068 P33176 P42025 P43234 P43235 P47755 P47756 P50570 P51149 P52732 P52907 P53634 P53680 P53992 P55735 P56377 P61163 P61966 P63010 P63167 P79483 P84077 Q00610 Q02224 Q02241 Q05193 Q07866 Q10567 Q12840 Q13409 Q13561 Q14203 Q14204 Q14807 Q15436 Q2VIQ3 Q30154 Q66K46 Q6P597 Q6PKD1 Q8N4N8 Q8NI77 Q92845 Q96CW1 Q96FJ2 Q96KX2 Q96NA2 Q96PC3 Q99538 Q99661 Q99962 Q9BTE1 Q9BXS5 Q9BXW6 Q9H0B6 Q9H0H5 Q9NS87 Q9NSK0 Q9NZ32 Q9UBX1 Q9UJW0 Q9ULI4 Q9UQ16 Q9Y496 Q9Y6B6 Q9Y6G9 Q9Y6Q5	ACTR10 ACTR11 ACTR1A ACTR1B ADTAA ADTAB ADTB1 ADTB2 ADTG AP17 AP19 AP1B1 AP1G1 AP1M1 AP1M2 AP1S1 AP1S2 AP1S3 AP2A1 AP2A2 AP2B1 AP2M1 AP2S1 ARF1 ARP10 ARP11 BAM22 CANX CAPAA3 CAPZA1 CAPZA2 CAPZA3 CAPZB CATL2 CD74 CENPE CLAPA1 CLAPA2 CLAPB1 CLAPB2 CLAPG1 CLAPM1 CLAPS1 CLAPS2 CLH17 CLTA CLTC CLTCL2 CLTNM CNSA2 CPPI CPSB CPSD CTRN1 CTRN2 CTSA CTSB CTSC CTSD CTSE CTSF CTSH CTSK CTSL CTSL1 CTSL2 CTSO CTSO1 CTSO2 CTSS CTSU CTSV D3S1231E DCTN1 DCTN2 DCTN22 DCTN3 DCTN4 DCTN5 DCTN50 DCTN6 DHC1 DHLAG DLC1 DLC2 DMA DMB DNCH1 DNCI1 DNCI2 DNCIC1 DNCIC2 DNCL DNCL1 DNCLC1 DNCLI1 DNCLI2 DNECL DNM DNM1 DNM2 DNM3 DYHC DYN2 DYNC1H1 DYNC1I1 DYNC1I2 DYNC1LI1 DYNC1LI2 DYNLL1 DYNLL2 EG5 FDC GILT GSG3 HDLC1 HIP9 HLA-DMA HLA-DMB HLA-DNA HLA-DOA HLA-DOB HLA-DP1A HLA-DP1B HLA-DPA1 HLA-DPB1 HLA-DQA1 HLA-DQA2 HLA-DQB HLA-DQB1 HLA-DQB2 HLA-DRA HLA-DRA1 HLA-DRB1 HLA-DRB3 HLA-DRB4 HLA-DRB5 HLA-DXA HLA-DXB HLA-DZA HLASB HYPJ IFI30 IP30 KIAA0034 KIAA0079 KIAA0109 KIAA0302 KIAA0325 KIAA0359 KIAA0755 KIAA0820 KIAA0899 KIAA0905 KIAA1236 KIAA1478 KID KIF11 KIF15 KIF18A KIF2 KIF20A KIF22 KIF23 KIF26A KIF2A KIF2B KIF2C KIF3 KIF3A KIF3AP KIF3B KIF3C KIF4 KIF4A KIF4B KIF5A KIF5B KIF5C KIFAP3 KLC KLC1 KLC2 KLC2L KLC3 KLC4 KLP2 KNS KNS1 KNS2 KNSL1 KNSL4 KNSL5 KNSL6 KNSL7 KNSL8 LAG3 LGMN LIC2 MGCRACGAP MKLP1 MKLP2 NKHC1 ORP1 OSBP8 OSBPL1 OSBPL1A OSBPL1B PPGB PRSC1 RAB6KIFL RAB7 RAB7A RACGAP1 RILP RING6 RING7 SAR1B SARA2 SARB SCA5 SEC13 SEC13A SEC13L1 SEC13R SEC23A SEC24A SEC24B SEC24C SEC24D SEC31A SEC31L1 SH3D2A SH3GL2 SMAP SPTBN2 TRIP5 WS3	Homo sapiens (human)
Defective GALE causes EDG	UDP-glucose 4-epimerase	Q14376	GALE	Homo sapiens (human)
Synthesis of 12-eicosatetraenoic acid derivatives	Arachidonate 12-lipoxygenase, 12R-type Glutathione peroxidase 1 Glutathione peroxidase 2 Hydroperoxide isomerase ALOXE3 Phospholipid hydroperoxide glutathione peroxidase GPX4 Polyunsaturated fatty acid lipoxygenase ALOX12 Polyunsaturated fatty acid lipoxygenase ALOX15	O75342 P07203 P16050 P18054 P18283 P36969 Q9BYJ1	12LO ALOX12 ALOX12B ALOX15 ALOXE3 GPX1 GPX2 GPX4 LOG12 LOG15	Homo sapiens (human)
MyD88-independent TLR4 cascade	Lymphocyte antigen 96 Monocyte differentiation antigen CD14 TIR domain-containing adapter molecule 1 TIR domain-containing adapter molecule 2 Toll-like receptor 4	O00206 P08571 Q86XR7 Q8IUC6 Q9Y6Y9	CD14 ESOP1 LY96 MD2 PRVTIRB TICAM1 TICAM2 TIRAP3 TIRP TLR4 TRAM TRIF	Homo sapiens (human)
Degradation of GLI2 by the proteasome	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Casein kinase I isoform alpha Cullin-1 E3 ubiquitin-protein ligase RBX1 F-box/WD repeat-containing protein 1A Glycogen synthase kinase-3 beta Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 S-phase kinase-associated protein 1 Suppressor of fused homolog Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Zinc finger protein GLI2 cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit gamma	A5LHX3 O00231 O00232 O00233 O00487 O14818 O43242 O75832 P0CG47 P0CG48 P10070 P17612 P17980 P20618 P22612 P22694 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P35998 P40306 P43686 P48556 P48729 P49720 P49721 P49841 P51665 P55036 P60896 P60900 P61289 P62191 P62195 P62333 P62877 P62979 P62987 P63208 Q06323 Q13200 Q13616 Q14997 Q15008 Q16401 Q8TAA3 Q92530 Q99436 Q99460 Q9UL46 Q9UMX1 Q9UNM6 Q9Y297	BTRC BTRCP C7orf76 CSNK1A1 CUL1 DSS1 EMC19 FBW1A FBXW1A GLI2 GSK3B HC2 HC3 HC8 HC9 HSPC IFI5111 KIAA0072 KIAA0077 KIAA0107 LMP10 LMP2 LMP7 LMPX LMPY MB1 MCB1 MECL1 MIP224 MOV34L MSS1 NU OCP2 PFAAP4 PKACA POH1 PRKACA PRKACB PRKACG PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 RBX1 RING10 RING12 RNF75 ROC1 RPS27A SEM1 SHFDG1 SHFM1 SKP1 SKP1A SUFU SUG1 SUG2 TBP1 TBP7 TCEB1L THP TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 X Y Y2 Z	Homo sapiens (human)
Synthesis of IPs in the nucleus	Inositol hexakisphosphate kinase 1 Inositol hexakisphosphate kinase 2 Inositol polyphosphate multikinase Inositol-pentakisphosphate 2-kinase	Q8NFU5 Q92551 Q9H8X2 Q9UHH9	C9orf12 IHPK1 IHPK2 IMPK IP6K1 IP6K2 IPMK IPPK KIAA0263	Homo sapiens (human)
Activation of NOXA and translocation to mitochondria	Cellular tumor antigen p53 Phorbol-12-myristate-13-acetate-induced protein 1 Transcription factor Dp-1 Transcription factor Dp-2 Transcription factor E2F1	P04637 Q01094 Q13794 Q14186 Q14188	DP1 DP2 E2F1 NOXA P53 PMAIP1 RBBP3 TFDP1 TFDP2 TP53	Homo sapiens (human)
G alpha (s) signalling events	3',5'-cyclic-AMP phosphodiesterase 4A 3',5'-cyclic-AMP phosphodiesterase 4C 3',5'-cyclic-AMP phosphodiesterase 4D 3',5'-cyclic-AMP phosphodiesterase 7B 5-hydroxytryptamine receptor 4 5-hydroxytryptamine receptor 6 5-hydroxytryptamine receptor 7 Adenosine receptor A2a Adenosine receptor A2b Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Adenylate cyclase type 9 Adrenocorticotropic hormone receptor Beta-1 adrenergic receptor Beta-2 adrenergic receptor Beta-3 adrenergic receptor Beta-adrenergic receptor kinase 1 Beta-arrestin-1 Beta-arrestin-2 Calcitonin gene-related peptide 1 Calcitonin gene-related peptide 2 Calcitonin gene-related peptide type 1 receptor Calcitonin receptor Calcitonin Corticoliberin Corticotropin-releasing factor receptor 1 Corticotropin-releasing factor receptor 2 Cysteinyl leukotriene receptor 2 D(1A) dopamine receptor D(1B) dopamine receptor Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B Follicle-stimulating hormone receptor Follitropin subunit beta G protein-coupled receptor kinase 3 G protein-coupled receptor kinase 5 G protein-coupled receptor kinase 6 G-protein coupled bile acid receptor 1 G-protein coupled receptor 15 G-protein coupled receptor 176 G-protein coupled receptor 20 G-protein coupled receptor 39 G-protein coupled receptor 83 G-protein coupled receptor 84 Gastric inhibitory polypeptide receptor Gastric inhibitory polypeptide Glucagon receptor Glucagon-like peptide 1 receptor Glucagon-like peptide 2 receptor Glycoprotein hormone alpha-2 Glycoprotein hormone beta-5 Glycoprotein hormones alpha chain Growth hormone-releasing hormone receptor Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(i) subunit alpha-1 Guanine nucleotide-binding protein G(i) subunit alpha-2 Guanine nucleotide-binding protein G(i) subunit alpha-3 Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Guanine nucleotide-binding protein G(t) subunit alpha-3 Guanine nucleotide-binding protein G(z) subunit alpha Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 High affinity 3',5'-cyclic-AMP phosphodiesterase 7A High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B Histamine H2 receptor Insulin-like 3 Islet amyloid polypeptide Lutropin subunit beta Lutropin-choriogonadotropic hormone receptor Melanocortin receptor 3 Melanocortin receptor 4 Melanocortin receptor 5 Melanocyte-stimulating hormone receptor Neuropeptide S receptor Neuropeptide S P2Y purinoceptor 11 Parathyroid hormone 2 receptor Parathyroid hormone-related protein Parathyroid hormone/parathyroid hormone-related peptide receptor Parathyroid hormone Pituitary adenylate cyclase-activating polypeptide type I receptor Pituitary adenylate cyclase-activating polypeptide Pro-adrenomedullin Pro-glucagon Pro-opiomelanocortin Probable G-protein coupled receptor 150 Probable G-protein coupled receptor 25 Probable G-protein coupled receptor 27 Probable G-protein coupled receptor 32 Probable G-protein coupled receptor 45 Prorelaxin H2 Prostacyclin receptor Prostaglandin D2 receptor Prostaglandin E2 receptor EP2 subtype Prostaglandin E2 receptor EP4 subtype Protein ADM2 Proto-oncogene tyrosine-protein kinase Src Putative trace amine-associated receptor 3 Receptor activity-modifying protein 1 Receptor activity-modifying protein 2 Receptor activity-modifying protein 3 Relaxin receptor 1 Relaxin receptor 2 Relaxin-3 Secretin receptor Secretin Somatoliberin Thyrotropin receptor Thyrotropin subunit beta Trace amine-associated receptor 1 Trace amine-associated receptor 2 Trace amine-associated receptor 5 Trace amine-associated receptor 6 Trace amine-associated receptor 8 Trace amine-associated receptor 9 Tuberoinfundibular peptide of 39 residues VIP peptides Vasoactive intestinal polypeptide receptor 1 Vasoactive intestinal polypeptide receptor 2 Vasopressin V2 receptor Vasopressin-neurophysin 2-copeptin cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A cGMP-dependent 3',5'-cyclic phosphodiesterase cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B	A8MTJ3 O00155 O00408 O14610 O14775 O14804 O43194 O43306 O60262 O60266 O60503 O60658 O60894 O60895 O60896 O75388 O95263 O95622 O95838 P01185 P01189 P01215 P01222 P01225 P01229 P01258 P01270 P01275 P01282 P01286 P04090 P04899 P06850 P06881 P07550 P08588 P08754 P09681 P09683 P0C0P6 P10092 P10997 P12272 P12931 P13945 P16473 P16520 P18509 P19086 P21728 P21918 P22888 P23945 P25021 P25098 P27815 P29274 P29275 P30518 P30988 P32121 P32241 P32245 P33032 P34947 P34969 P34998 P35318 P35408 P35626 P40145 P41586 P41587 P41968 P43116 P43119 P43220 P43250 P47871 P47872 P48546 P49190 P49407 P49685 P50150 P50151 P50406 P51460 P51828 P54750 P59768 P61952 P62873 P62879 P63092 P63096 P63211 P63215 P63218 Q01064 Q01718 Q01726 Q02643 Q03431 Q08462 Q08493 Q08499 Q08828 Q13258 Q13324 Q13370 Q13639 Q13946 Q14432 Q14439 Q16602 Q5JWF2 Q6W5P4 Q7Z4H4 Q86YW7 Q8NFM4 Q8NGU9 Q8TDU6 Q8WXD0 Q8WXF3 Q969N4 Q96A98 Q96G91 Q96RI8 Q96RI9 Q96RJ0 Q96T91 Q99678 Q9HAV0 Q9HBX9 Q9HCR9 Q9NP56 Q9NQS5 Q9NS67 Q9NS75 Q9NYM4 Q9P1P4 Q9P1P5 Q9P2W3 Q9UBI6 Q9UK08 Q9Y233 Q9Y5Y3	ACTHR ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 ADCYAP1 ADCYAP1R1 ADHR ADM ADM2 ADORA2 ADORA2A ADORA2B ADRB1 ADRB1R ADRB2 ADRB2R ADRB3 ADRB3R ADRBK1 ADRBK2 AM AM2 ARB2 ARR1 ARR2 ARRB1 ARRB2 ARVP AVP AVPR2 B1AR B2AR B3AR BARK BARK1 BARK2 CALC1 CALC2 CALCA CALCB CALCR CALCRL CGA CGRPR CRF2R CRFR CRFR1 CRH CRH2R CRHR CRHR1 CRHR2 CYSLT2 CYSLT2R CYSLTR2 DIR DIR3 DPDE1 DPDE2 DPDE3 DRD1 DRD1B DRD1L2 DRD5 EX33 FSHB FSHR GCG GCGR GHRF GHRH GHRHR GIP GIPR GLP1R GLP2R GNAI1 GNAI2 GNAI2B GNAI3 GNAS GNAS1 GNAT3 GNAZ GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 GPA2 GPB5 GPBAR1 GPHA2 GPHB5 GPR102 GPR106 GPR15 GPR150 GPR154 GPR176 GPR20 GPR25 GPR27 GPR32 GPR39 GPR45 GPR57 GPR58 GPR72 GPR83 GPR84 GPRA GPRK5 GPRK6 GREAT GRK2 GRK3 GRK5 GRK6 GSP HRH2 HTR4 HTR6 HTR7 IAPP INSL3 INSL7 JP05 KIAA0037 KIAA0422 KIAA0511 KIAA0520 KIAA1060 KIAA1540 LCGR LGR1 LGR2 LGR3 LGR7 LGR8 LHB LHCGR LHRHR MC1R MC2R MC3R MC4R MC5R MSHR NPS NPSR1 P2RY11 PDE10A PDE11A PDE1A PDE1B PDE2A PDE3A PDE3B PDE4A PDE4C PDE4D PDE7A PDE7B PDE8A PDE8B PDES1B PGR14 PNR POMC PRIPR PTGDR PTGER2 PTGER4 PTGIR PTH PTH1R PTH2 PTH2R PTHLH PTHR PTHR1 PTHR2 PTHRP RAMP1 RAMP2 RAMP3 RLF RLN2 RLN3 RLNL RXFP1 RXFP2 RXN3 SCT SCTR SRC SRC1 SREB1 TA1 TA3 TA4 TA5 TAAR1 TAAR2 TAAR3 TAAR3P TAAR5 TAAR6 TAAR8 TAAR9 TAR1 TAR3 TAR4 TAR5 TGR5 TIP39 TIPF39 TRAR1 TRAR3 TRAR4 TRAR5 TSHB TSHR V2R VIP VIP2R VIPR1 VIPR2 VP ZINS4 ZLUT1 ZSIG51	Homo sapiens (human)
GRB2 events in EGFR signaling	Amphiregulin Epidermal growth factor receptor Epigen GTPase HRas GTPase NRas Pro-epidermal growth factor Probetacellulin Proepiregulin Proheparin-binding EGF-like growth factor Protransforming growth factor alpha Son of sevenless homolog 1	O14944 P00533 P01111 P01112 P01133 P01135 P15514 P35070 Q07889 Q6UW88 Q99075	AREG AREGB BTC DTR DTS EGF EGFR EPGN ERBB ERBB1 EREG HBEGF HEGFL HER1 HRAS HRAS1 NRAS SDGF SOS1 TGFA	Homo sapiens (human)
Erythropoietin activates STAT5	Erythropoietin receptor Erythropoietin Insulin receptor substrate 2 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Lyn	O60674 P01588 P07948 P19235 P42229 P51692 Q9Y4H2	EPO EPOR IRS2 JAK2 JTK8 LYN STAT5 STAT5A STAT5B	Homo sapiens (human)
Resistance of ERBB2 KD mutants to neratinib	Erbin Heat shock protein HSP 90-alpha Hsp90 co-chaperone Cdc37 Receptor tyrosine-protein kinase erbB-2	P04626 P07900 Q16543 Q96RT1	CDC37 CDC37A ERBB2 ERBB2IP ERBIN HER2 HSP90A HSP90AA1 HSPC1 HSPCA KIAA1225 LAP2 MLN19 NEU NGL	Homo sapiens (human)
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits	ATP-sensitive inward rectifier potassium channel 10 ATP-sensitive inward rectifier potassium channel 12 ATP-sensitive inward rectifier potassium channel 15 G protein-activated inward rectifier potassium channel 1 G protein-activated inward rectifier potassium channel 2 G protein-activated inward rectifier potassium channel 3 G protein-activated inward rectifier potassium channel 4 Gamma-aminobutyric acid type B receptor subunit 1 Gamma-aminobutyric acid type B receptor subunit 2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Inward rectifier potassium channel 16 Inward rectifier potassium channel 2 Inward rectifier potassium channel 4	O14610 O14775 O60262 O75899 P16520 P48050 P48051 P48544 P48549 P50150 P50151 P59768 P61952 P62873 P62879 P63211 P63215 P63218 P63252 P78508 Q14500 Q92806 Q99712 Q9HAV0 Q9NPI9 Q9P2W3 Q9UBI6 Q9UBS5 Q9UK08	GABBR1 GABBR2 GIRK1 GIRK2 GIRK3 GIRK4 GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 GPR51 GPRC3A GPRC3B IRK1 IRK2 IRK3 KATP2 KCNJ10 KCNJ12 KCNJ14 KCNJ15 KCNJ16 KCNJ2 KCNJ3 KCNJ4 KCNJ5 KCNJ6 KCNJ7 KCNJ9 KCNJN1	Homo sapiens (human)
Mitochondrial translation initiation	Alpha-ketoglutarate dehydrogenase component 4 GTPase Era, mitochondrial Large ribosomal subunit protein bL12m Large ribosomal subunit protein bL17m Large ribosomal subunit protein bL19m Large ribosomal subunit protein bL20m Large ribosomal subunit protein bL21m Large ribosomal subunit protein bL27m Large ribosomal subunit protein bL28m Large ribosomal subunit protein bL32m Large ribosomal subunit protein bL33m Large ribosomal subunit protein bL34m Large ribosomal subunit protein bL35m Large ribosomal subunit protein bL36m Large ribosomal subunit protein bL9m Large ribosomal subunit protein mL37 Large ribosomal subunit protein mL38 Large ribosomal subunit protein mL39 Large ribosomal subunit protein mL40 Large ribosomal subunit protein mL41 Large ribosomal subunit protein mL42 Large ribosomal subunit protein mL43 Large ribosomal subunit protein mL44 Large ribosomal subunit protein mL45 Large ribosomal subunit protein mL46 Large ribosomal subunit protein mL48 Large ribosomal subunit protein mL49 Large ribosomal subunit protein mL50 Large ribosomal subunit protein mL51 Large ribosomal subunit protein mL52 Large ribosomal subunit protein mL53 Large ribosomal subunit protein mL54 Large ribosomal subunit protein mL55 Large ribosomal subunit protein mL62 Large ribosomal subunit protein mL63 Large ribosomal subunit protein mL64 Large ribosomal subunit protein mL65 Large ribosomal subunit protein mL66 Large ribosomal subunit protein uL10m Large ribosomal subunit protein uL11m Large ribosomal subunit protein uL13m Large ribosomal subunit protein uL14m Large ribosomal subunit protein uL15m Large ribosomal subunit protein uL16m Large ribosomal subunit protein uL18m Large ribosomal subunit protein uL1m Large ribosomal subunit protein uL22m Large ribosomal subunit protein uL23m Large ribosomal subunit protein uL24m Large ribosomal subunit protein uL29m Large ribosomal subunit protein uL2m Large ribosomal subunit protein uL30m Large ribosomal subunit protein uL3m Large ribosomal subunit protein uL4m Methionyl-tRNA formyltransferase, mitochondrial Mitochondrial inner membrane protein OXA1L Small ribosomal subunit protein bS16m Small ribosomal subunit protein bS18m Small ribosomal subunit protein bS1m Small ribosomal subunit protein bS21m Small ribosomal subunit protein bS6m Small ribosomal subunit protein mS22 Small ribosomal subunit protein mS23 Small ribosomal subunit protein mS25 Small ribosomal subunit protein mS26 Small ribosomal subunit protein mS27 Small ribosomal subunit protein mS29 Small ribosomal subunit protein mS31 Small ribosomal subunit protein mS33 Small ribosomal subunit protein mS34 Small ribosomal subunit protein mS35 Small ribosomal subunit protein mS37 Small ribosomal subunit protein mS38 Small ribosomal subunit protein mS39 Small ribosomal subunit protein mS40 Small ribosomal subunit protein uS10m Small ribosomal subunit protein uS11m Small ribosomal subunit protein uS12m Small ribosomal subunit protein uS14m Small ribosomal subunit protein uS15m Small ribosomal subunit protein uS17m Small ribosomal subunit protein uS2m Small ribosomal subunit protein uS3m Small ribosomal subunit protein uS5m Small ribosomal subunit protein uS7m Small ribosomal subunit protein uS9m Translation initiation factor IF-2, mitochondrial Translation initiation factor IF-3, mitochondrial	O15235 O60783 O75394 O75616 P09001 P46199 P49406 P51398 P52815 P82650 P82663 P82664 P82673 P82675 P82909 P82912 P82914 P82921 P82930 P82932 P82933 Q13084 Q13405 Q14197 Q15070 Q16540 Q4U2R6 Q5T653 Q6P161 Q6P1L8 Q7Z2W9 Q7Z7F7 Q7Z7H8 Q86TS9 Q8IXM3 Q8N5N7 Q8N983 Q8TAE8 Q8TCC3 Q92552 Q92665 Q96A35 Q96BP2 Q96DP5 Q96DV4 Q96EL2 Q96EL3 Q96EY7 Q96GC5 Q9BQ48 Q9BQC6 Q9BRJ2 Q9BYC8 Q9BYC9 Q9BYD1 Q9BYD2 Q9BYD3 Q9BYD6 Q9BYN8 Q9BZE1 Q9H0U6 Q9H2K0 Q9H2W6 Q9H9J2 Q9HD33 Q9NP92 Q9NQ50 Q9NRX2 Q9NVS2 Q9NWT8 Q9NWU5 Q9NX20 Q9NYK5 Q9NZE8 Q9P015 Q9P0J6 Q9P0M9 Q9Y291 Q9Y2Q9 Q9Y2R5 Q9Y2R9 Q9Y399 Q9Y3B7 Q9Y3D3 Q9Y3D5 Q9Y3D9 Q9Y676 Q9Y6G3	AIP AKIP AURKAIP1 BMRP BRIP1 C10orf34 C11orf4 C15orf4 C20orf193 C21orf101 C21orf92 C2orf1 C3orf5 C6orf14 CHCHD1 DAP3 DS1 ERAL1 FMT FMT1 GADD45GIP1 HERA ICT1 IMOGN38 KGD4 KIAA0104 KIAA0264 L23MRP LIECG2 LIP2 MAAT1 MRL3 MRP63 MRP64 MRPL1 MRPL10 MRPL11 MRPL12 MRPL13 MRPL14 MRPL15 MRPL16 MRPL17 MRPL18 MRPL19 MRPL2 MRPL20 MRPL21 MRPL22 MRPL23 MRPL24 MRPL25 MRPL27 MRPL28 MRPL3 MRPL30 MRPL31 MRPL32 MRPL33 MRPL34 MRPL35 MRPL36 MRPL37 MRPL38 MRPL39 MRPL4 MRPL40 MRPL41 MRPL42 MRPL43 MRPL44 MRPL45 MRPL46 MRPL47 MRPL48 MRPL49 MRPL5 MRPL50 MRPL51 MRPL52 MRPL53 MRPL54 MRPL55 MRPL57 MRPL58 MRPL59 MRPL7 MRPL8 MRPL9 MRPS10 MRPS11 MRPS12 MRPS14 MRPS15 MRPS16 MRPS17 MRPS18A MRPS18B MRPS18C MRPS2 MRPS21 MRPS22 MRPS23 MRPS24 MRPS25 MRPS26 MRPS27 MRPS28 MRPS29 MRPS30 MRPS31 MRPS32 MRPS33 MRPS34 MRPS35 MRPS36 MRPS37 MRPS38 MRPS39 MRPS5 MRPS6 MRPS7 MRPS9 MTFMT MTIF2 MTIF3 NCM1 NLVCF NOF1 OXA1L PDCD9 PLINP1 PRG6 PTCD3 RPL23L RPML12 RPML2 RPML25 RPML27 RPML28 RPML3 RPML31 RPML32 RPML5 RPML8 RPMS11 RPMS12 RPMS13 RPMS15 RPMS16 RPMS17 RPMS21 RPMS22 RPMS25 RPMS6 RPMS9 RPSM12 URIM	Homo sapiens (human)
Other interleukin signaling	Alpha-taxilin Caspase-3 Granulocyte colony-stimulating factor receptor Granulocyte colony-stimulating factor Interferon lambda receptor 1 Interferon lambda-1 Interleukin-10 receptor subunit beta Interleukin-32 Interleukin-34 Macrophage colony-stimulating factor 1 receptor Macrophage colony-stimulating factor 1 Myeloblastin Non-receptor tyrosine-protein kinase TYK2 Pro-interleukin-16 Receptor-type tyrosine-protein phosphatase zeta Synaptosomal-associated protein 25 Syndecan-1 Syntaxin-1A Syntaxin-3 Syntaxin-4 Syntaxin-binding protein 2 T-cell surface glycoprotein CD4 Tyrosine-protein kinase JAK1 Vesicle-associated membrane protein 2	P01730 P07333 P09603 P09919 P18827 P23458 P23471 P24001 P24158 P29597 P40222 P42574 P60880 P63027 Q08334 Q12846 Q13277 Q14005 Q15833 Q16623 Q6ZMJ4 Q8IU54 Q8IU57 Q99062	C16orf77 C17orf33 CASP3 CD4 CPP32 CRFB4 CSF1 CSF1R CSF3 CSF3R D21S58 D21S66 FMS GCSF GCSFR HTPZP2 IFNL1 IFNLR1 IL10RB IL16 IL28RA IL29 IL32 IL34 JAK1 JAK1A JAK1B LICR2 MBN NK4 PRTN3 PTPRZ PTPRZ1 PTPRZ2 PTPZ SDC SDC1 SNAP SNAP25 STX1 STX1A STX3 STX3A STX4 STX4A STXBP2 SYB2 TAIF TXLN TXLNA TYK2 UNC18B VAMP2 ZCYTO21	Homo sapiens (human)
FRS-mediated FGFR1 signaling	Fibroblast growth factor 10 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 22 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor 4 Fibroblast growth factor 6 Fibroblast growth factor 9 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor substrate 3 GTPase HRas GTPase NRas Son of sevenless homolog 1 Tyrosine-protein phosphatase non-receptor type 11	O15520 O43559 P01111 P01112 P05230 P08620 P09038 P10767 P11487 P31371 Q06124 Q07889 Q8WU20 Q9GZV9 Q9HCT0 Q9NP95	FGF1 FGF10 FGF2 FGF20 FGF22 FGF23 FGF3 FGF4 FGF6 FGF9 FGFA FGFB FRS2 FRS3 HRAS HRAS1 HST HST2 HSTF1 HSTF2 HYPF INT2 KS3 NRAS PTP2C PTPN11 SHPTP2 SOS1	Homo sapiens (human)
G2/M DNA replication checkpoint	Cyclin-dependent kinase 1 G2/mitotic-specific cyclin-B1 G2/mitotic-specific cyclin-B2 Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase Wee1-like protein kinase	O95067 P06493 P14635 P30291 Q99640	CCNB CCNB1 CCNB2 CDC2 CDC28A CDK1 CDKN1 MYT1 P34CDC2 PKMYT1 WEE1	Homo sapiens (human)
Beta-oxidation of pristanoyl-CoA	Acyl-coenzyme A oxidase-like protein Acyl-coenzyme A thioesterase 8 Alpha-methylacyl-CoA racemase Carnitine O-acetyltransferase Peroxisomal acyl-coenzyme A oxidase 2 Peroxisomal acyl-coenzyme A oxidase 3 Peroxisomal carnitine O-octanoyltransferase Peroxisomal multifunctional enzyme type 2	O14734 O15254 P43155 P51659 Q99424 Q9NUZ1 Q9UHK6 Q9UKG9	ACOT8 ACOX2 ACOX3 ACOXL ACTEIII AMACR BRCOX CAT1 COT CRAT CROT EDH17B4 HSD17B4 PRCOX PTE1 SDR8C1	Homo sapiens (human)
Constitutive Signaling by EGFRvIII	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 E3 ubiquitin-protein ligase CBL Epidermal growth factor receptor GRB2-associated-binding protein 1 GTPase HRas GTPase NRas Heat shock protein HSP 90-alpha Hsp90 co-chaperone Cdc37 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Pro-epidermal growth factor SHC-transforming protein 1 Son of sevenless homolog 1	P00533 P01111 P01112 P01133 P07900 P19174 P22681 P27986 P29353 P42336 Q07889 Q13480 Q16543	CBL CBL2 CDC37 CDC37A EGF EGFR ERBB ERBB1 GAB1 GRB1 HER1 HRAS HRAS1 HSP90A HSP90AA1 HSPC1 HSPCA NRAS PIK3CA PIK3R1 PLC1 PLCG1 RNF55 SHC SHC1 SHCA SOS1	Homo sapiens (human)
HDR through Homologous Recombination (HRR)	26S proteasome complex subunit SEM1 BRCA1-associated RING domain protein 1 Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN Breast cancer type 1 susceptibility protein Breast cancer type 2 susceptibility protein DNA endonuclease RBBP8 DNA polymerase delta catalytic subunit DNA polymerase delta subunit 2 DNA polymerase delta subunit 3 DNA polymerase delta subunit 4 DNA polymerase epsilon catalytic subunit A DNA polymerase epsilon subunit 2 DNA polymerase epsilon subunit 3 DNA polymerase epsilon subunit 4 DNA polymerase eta DNA polymerase kappa DNA repair protein RAD50 DNA repair protein RAD51 homolog 1 DNA repair protein RAD51 homolog 2 DNA repair protein RAD51 homolog 3 DNA repair protein RAD51 homolog 4 DNA repair protein XRCC2 DNA repair protein XRCC3 DNA replication ATP-dependent helicase/nuclease DNA2 DNA topoisomerase 3-alpha Double-strand break repair protein MRE11 Exonuclease 1 Fanconi anemia group J protein Histone acetyltransferase KAT5 Nibrin Partner and localizer of BRCA2 Polyubiquitin-B Polyubiquitin-C Proliferating cell nuclear antigen RAD51-associated protein 1 RecQ-like DNA helicase BLM RecQ-mediated genome instability protein 1 RecQ-mediated genome instability protein 2 Replication factor C subunit 1 Replication factor C subunit 2 Replication factor C subunit 3 Replication factor C subunit 4 Replication factor C subunit 5 Replication protein A 14 kDa subunit Replication protein A 32 kDa subunit Replication protein A 70 kDa DNA-binding subunit Serine-protein kinase ATM Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O15315 O43502 O43542 O43543 O60934 O75771 P0CG47 P0CG48 P12004 P15927 P27694 P28340 P35244 P35249 P35250 P35251 P38398 P40937 P40938 P49005 P49959 P51530 P51587 P54132 P56282 P60896 P62979 P62987 Q06609 Q07864 Q13315 Q13472 Q14191 Q15054 Q86YC2 Q92878 Q92993 Q96B01 Q96E14 Q99708 Q99728 Q9BX63 Q9H9A7 Q9HCU8 Q9NR33 Q9NRF9 Q9UBT6 Q9UQ84 Q9Y253	ATM BACH1 BARD1 BLM BRCA1 BRCA2 BRIP1 C16orf75 C7orf76 C9orf76 CHRAC17 CTIP DINB1 DNA2 DNA2L DPE2 DSS1 EXO1 EXOI FACD FANCD1 FANCJ FANCN HEX1 HNGS1 HTATIP KAT5 KIAA0039 KIAA0083 MRE11 MRE11A NBN NBS NBS1 P95 PALB2 PCNA PIR51 POLD POLD1 POLD2 POLD3 POLD4 POLDS POLE POLE1 POLE2 POLE3 POLE4 POLH POLK RAD30 RAD30A RAD50 RAD51 RAD51A RAD51AP1 RAD51B RAD51C RAD51D RAD51L1 RAD51L2 RAD51L3 RBBP8 REC2 RECA RECQ2 RECQ3 RECQL2 RECQL3 REPA1 REPA2 REPA3 RFC1 RFC140 RFC2 RFC3 RFC4 RFC5 RMI1 RMI2 RNF53 RPA1 RPA14 RPA2 RPA3 RPA32 RPA34 RPA70 RPS27A SEM1 SHFDG1 SHFM1 TIP60 TOP3 TOP3A UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 WRN XPV XRCC2 XRCC3	Homo sapiens (human)
Amino acids regulate mTORC1	Cytosolic arginine sensor for mTORC1 subunit 1 Cytosolic arginine sensor for mTORC1 subunit 2 Folliculin-interacting protein 1 Folliculin-interacting protein 2 Folliculin GATOR1 complex protein DEPDC5 GATOR1 complex protein NPRL2 GATOR1 complex protein NPRL3 GATOR2 complex protein MIOS GATOR2 complex protein WDR24 GATOR2 complex protein WDR59 GTP-binding protein Rheb KICSTOR complex protein ITFG2 KICSTOR complex protein SZT2 KICSTOR complex protein kaptin KICSTOR subunit 2 Neutral amino acid transporter 9 Nucleoporin SEH1 Protein SEC13 homolog Ragulator complex protein LAMTOR1 Ragulator complex protein LAMTOR2 Ragulator complex protein LAMTOR3 Ragulator complex protein LAMTOR4 Ragulator complex protein LAMTOR5 Ras-related GTP-binding protein A Ras-related GTP-binding protein B Ras-related GTP-binding protein C Ras-related GTP-binding protein D Regulatory-associated protein of mTOR S-adenosylmethionine sensor upstream of mTORC1 SH3 domain-binding protein 4 Serine/threonine-protein kinase mTOR Sestrin-1 Sestrin-2 Target of rapamycin complex subunit LST8 V-type proton ATPase 116 kDa subunit a 3 V-type proton ATPase 16 kDa proteolipid subunit c V-type proton ATPase 21 kDa proteolipid subunit c'' V-type proton ATPase catalytic subunit A V-type proton ATPase subunit B, brain isoform V-type proton ATPase subunit B, kidney isoform V-type proton ATPase subunit C 1 V-type proton ATPase subunit C 2 V-type proton ATPase subunit D V-type proton ATPase subunit E 1 V-type proton ATPase subunit E 2 V-type proton ATPase subunit F V-type proton ATPase subunit G 1 V-type proton ATPase subunit G 2 V-type proton ATPase subunit G 3 V-type proton ATPase subunit H V-type proton ATPase subunit d 1 V-type proton ATPase subunit d 2 V-type proton ATPase subunit e 1 V-type proton ATPase subunit e 2	A6NHX0 O15342 O43504 O75140 O75348 O95670 P15313 P21281 P21283 P27449 P36543 P38606 P42345 P55735 P58004 P61421 Q0VGL1 Q12980 Q13488 Q15382 Q16864 Q1RMZ1 Q5T011 Q5VZM2 Q6IAA8 Q6PJI9 Q7L523 Q8N122 Q8N8Y2 Q8NBW4 Q8NEY4 Q8NFG4 Q8NHE4 Q8TF40 Q8WTW4 Q8WTX7 Q969R8 Q96A05 Q96EE3 Q96LB4 Q96MD2 Q96S15 Q99437 Q9BVC4 Q9HB90 Q9NQL2 Q9NXC5 Q9P0V3 Q9P278 Q9UHA4 Q9UI12 Q9Y2Q5 Q9Y5K8 Q9Y664 Q9Y6P5	ATP6A1 ATP6B1 ATP6B2 ATP6C ATP6D ATP6E ATP6E1 ATP6E2 ATP6EL2 ATP6F ATP6G ATP6G1 ATP6G2 ATP6G3 ATP6H ATP6J ATP6L ATP6M ATP6N1C ATP6S14 ATP6V0A3 ATP6V0B ATP6V0C ATP6V0D1 ATP6V0D2 ATP6V0E ATP6V0E1 ATP6V0E2 ATP6V0E2L ATP6V1A ATP6V1A1 ATP6V1B1 ATP6V1B2 ATP6V1C1 ATP6V1C2 ATP6V1D ATP6V1E1 ATP6V1E2 ATP6V1EL2 ATP6V1F ATP6V1G1 ATP6V1G2 ATP6V1G3 ATP6V1H ATPL BHD BMT2 BOG25 C11orf59 C12orf66 C16orf21 C16orf35 C1orf84 C7orf32 C7orf59 C7orf60 CASTOR1 CASTOR2 CGTHBA D3S1231E DEPDC5 EHB10 FLCN FNIP1 FNIP2 FNIPL FRAP FRAP1 FRAP2 GATSL1 GATSL2 GATSL3 GBL HBXIP Hi95 ITFG2 KIAA0467 KIAA0645 KIAA1303 KIAA1450 KIAA1923 KIAA1961 KICS2 KPTN LAMTOR1 LAMTOR2 LAMTOR3 LAMTOR4 LAMTOR5 LST8 MAP2K1IP1 MAPBPIP MAPKSP1 MAPO1 MARE MIOS MLST8 MTOR NG38 NPRL2 NPRL3 PA26 PDRO RAFT1 RAPT1 RAPTOR RHEB RHEB2 ROBLD3 RPTOR RRAGA RRAGB RRAGC RRAGD SAMTOR SEC13 SEC13A SEC13L SEC13L1 SEC13R SEH1 SEH1L SESN1 SESN2 SEST1 SEST2 SH3BP4 SLC38A9 SZT2 TCIRG1 TTP TUSC4 URLC11 VATB VATC VATD VATF VPATPD VPP2 VPP3 WDR24 WDR59 XIP	Homo sapiens (human)
Truncations of AMER1 destabilize the destruction complex	APC membrane recruitment protein 1 Adenomatous polyposis coli protein Axin-1 Casein kinase I isoform alpha Glycogen synthase kinase-3 beta Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform	O15169 P25054 P30153 P30154 P48729 P49841 P62714 P67775 Q13362 Q14738 Q15172 Q15173 Q16537 Q5JTC6	AMER1 APC AXIN AXIN1 CSNK1A1 DP2.5 FAM123B GSK3B KIAA0044 PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E WTX	Homo sapiens (human)
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation	Interleukin-1 receptor-associated kinase-like 2 Lymphocyte antigen 96 Mitogen-activated protein kinase kinase kinase 7 Monocyte differentiation antigen CD14 Polyubiquitin-B Polyubiquitin-C TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 TIR domain-containing adapter molecule 1 TIR domain-containing adapter molecule 2 TNF receptor-associated factor 6 Toll-like receptor 4 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00206 O43187 O43318 P08571 P0CG47 P0CG48 P62979 P62987 Q15750 Q86XR7 Q8IUC6 Q8N5C8 Q9NYJ8 Q9Y4K3 Q9Y6Y9	CD14 ESOP1 IRAK2 KIAA0733 LY96 MAP3K7 MAP3K7IP1 MAP3K7IP2 MAP3K7IP3 MD2 PRVTIRB RNF85 RPS27A TAB1 TAB2 TAB3 TAK1 TICAM1 TICAM2 TIRAP3 TIRP TLR4 TRAF6 TRAM TRIF UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Homo sapiens (human)

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