Metal sequestration by antimicrobial proteins
|
|
|
- CAGA
- CAGB
- CFAG
- GIG12
- HNL
- LCN2
- LF
- LTF
- MRP14
- MRP8
- NGAL
- PSOR1
- S100A15
- S100A7
- S100A7A
- S100A7C
- S100A7L1
- S100A8
- S100A9
|
|
RHO GTPases Activate NADPH Oxidases
|
|
|
- CAGA
- CAGB
- CFAG
- CSBP
- CSBP1
- CSBP2
- CSPB1
- CYBA
- CYBB
- ERK1
- ERK2
- MAPK1
- MAPK11
- MAPK14
- MAPK3
- MOX1
- MOX2
- MRP14
- MRP8
- MXI2
- NCF1
- NCF2
- NCF4
- NOH1
- NOX1
- NOX2
- NOX3
- NOXA1
- NOXA2
- NOXO1
- NOXO2
- P41NOX
- P51NOX
- P67PHOX
- PIK3C3
- PIK3R4
- PIN1
- PKC2
- PKCA
- PKCB
- PKCD
- PRKACA
- PRKCA
- PRKCB
- PRKCB1
- PRKCD
- PRKCZ
- PRKM1
- PRKM11
- PRKM2
- PRKM3
- RAC1
- RAC2
- S100A8
- S100A9
- SAPK2
- SAPK2A
- SAPK2B
- SH3PXD1A
- SH3PXD4
- SH3PXD5
- TC25
- VPS15
- VPS34
|
|
Nectin/Necl trans heterodimerization
|
|
|
- CADM1
- CADM3
- HVEB
- HVEC
- IGSF4
- IGSF4A
- IGSF4B
- LNIR
- NECL1
- NECL2
- NECTIN1
- NECTIN2
- NECTIN3
- NECTIN4
- PRR1
- PRR2
- PRR3
- PRR4
- PVR
- PVRL1
- PVRL2
- PVRL3
- PVRL4
- PVS
- SYNCAM
- SYNCAM3
- TSLC1
- TSLL1
|
|
Pyrimidine biosynthesis
|
|
|
|
|
Apoptosis induced DNA fragmentation
|
|
|
- CAD
- CASP3
- CPP32
- DFF1
- DFF2
- DFF40
- DFF45
- DFFA
- DFFB
- H1-0
- H1-1
- H1-2
- H1-3
- H1-4
- H1-5
- H1F0
- H1F1
- H1F2
- H1F3
- H1F4
- H1F5
- H1FV
- HIST1H1A
- HIST1H1B
- HIST1H1C
- HIST1H1D
- HIST1H1E
- HMG1
- HMG2
- HMGB1
- HMGB2
- KPNA1
- KPNB1
- NTF97
- RCH2
|
|
Presynaptic depolarization and calcium channel opening
|
|
|
- CACH4
- CACH5
- CACH6
- CACN3
- CACNA1A
- CACNA1B
- CACNA1E
- CACNA2D1
- CACNA2D2
- CACNA2D3
- CACNB1
- CACNB2
- CACNB3
- CACNB4
- CACNG2
- CACNG4
- CACNL1A4
- CACNL1A5
- CACNL1A6
- CACNLB1
- CACNLB2
- CACNLB3
- CACNLB4
- KIAA0558
- MYSB
|
|
Phase 0 - rapid depolarisation
|
|
|
- CACH2
- CACN2
- CACNA1C
- CACNA2D2
- CACNB1
- CACNB2
- CACNG4
- CACNG6
- CACNG7
- CACNG8
- CACNL1A1
- CACNLB1
- CACNLB2
- CALM
- CALM1
- CAM
- CAM1
- CAM2
- CAMK
- CAMK-II
- CAMK2
- CAMK2A
- CAMK2B
- CAMK2D
- CAMK2G
- CAMKA
- CAMKB
- CAMKD
- CAMKG
- CCHL1A1
- FGF11
- FGF12
- FGF12B
- FGF13
- FGF14
- FHF1
- FHF2
- FHF3
- FHF4
- HBA
- KIAA0558
- KIAA0968
- KIAA1158
- KIAA1356
- MED
- MOG1
- MYSB
- NAC1
- NAC2
- NAC3
- NENA
- RANGNRF
- RANGRF
- SCN1
- SCN10A
- SCN11A
- SCN12A
- SCN1A
- SCN1B
- SCN2A
- SCN2A1
- SCN2A2
- SCN2B
- SCN3A
- SCN3B
- SCN4A
- SCN4B
- SCN5A
- SCN6A
- SCN7A
- SCN8A
- SCN9A
- SNS2
|
|
Reversible hydration of carbon dioxide
|
|
|
- CA1
- CA12
- CA13
- CA14
- CA2
- CA3
- CA4
- CA5
- CA5A
- CA5B
- CA6
- CA7
- CA9
- G250
- MN
|
|
Membrane binding and targetting of GAG proteins
|
|
|
- C9orf28
- CFBP
- FAM125A
- FAM125B
- HCRP1
- MVB12A
- MVB12B
- NMT2
- PML39
- RPS27A
- TSG101
- UBA52
- UBA80
- UBAP1
- UBB
- UBC
- UBCEP1
- UBCEP2
- VPS28
- VPS37A
- VPS37B
- VPS37C
- VPS37D
- WBSCR24
- gag
|
|
Interleukin-33 signaling
|
|
|
- C9orf26
- DER4
- IL1F11
- IL1RL1
- IL33
- NFHEV
- ST2
- T1
|
|
Other semaphorin interactions
|
|
|
- C9orf164
- CD100
- CD108
- CD45
- CD72
- DAP12
- FNRB
- ITGA1
- ITGB1
- KARAP
- KIAA0331
- KIAA0463
- KIAA0620
- KIAA1206
- KIAA1368
- KIAA1479
- KIAA1550
- MDF2
- MSK12
- NOV
- OCT
- PLXN1
- PLXN2
- PLXN6
- PLXNA1
- PLXNA2
- PLXNA4
- PLXNA4A
- PLXNA4B
- PLXNB3
- PLXNC1
- PLXND1
- PTPRC
- SEMA3E
- SEMA4A
- SEMA4D
- SEMA5A
- SEMA6A
- SEMA6D
- SEMA7A
- SEMAB
- SEMAF
- SEMAH
- SEMAJ
- SEMAL
- SEMAQ
- SEMB
- TREM2
- TYROBP
- VESPR
|
|
Synthesis of IPs in the nucleus
|
|
|
- C9orf12
- IHPK1
- IHPK2
- IMPK
- IP6K1
- IP6K2
- IPMK
- IPPK
- KIAA0263
|
|
Glycerophospholipid catabolism
|
|
|
- C9orf111
- ENPP6
- GDE1
- GDE2
- GDE4
- GDE7
- GDPD1
- GDPD3
- GDPD5
- MIR16
- NTE
- PNPLA6
- PNPLA7
|
|
Lysosphingolipid and LPA receptors
|
|
|
- C9orf108
- C9orf47
- CHEDG1
- EDG1
- EDG2
- EDG3
- EDG4
- EDG5
- EDG6
- EDG7
- EDG8
- GPR92
- GPR93
- KIAA0455
- LPA1
- LPA2
- LPA3
- LPAR1
- LPAR2
- LPAR3
- LPAR5
- LPPR1
- LPPR2
- LPPR3
- LPPR4
- LPPR5
- PAP2D
- PHP1
- PHP2
- PLPPR1
- PLPPR2
- PLPPR3
- PLPPR4
- PLPPR5
- PRG1
- PRG2
- PRG3
- PRG4
- PRG5
- S1PR1
- S1PR2
- S1PR3
- S1PR4
- S1PR5
|
|
Synthesis of PIPs at the late endosome membrane
|
|
|
- C8orf9
- CG2
- FIG4
- KIAA0274
- KIAA0647
- KIAA0981
- KIAA1073
- MTM1
- MTMR2
- MTMR4
- MTMR7
- MTMR8
- MTMR9
- PIK3C2A
- PIK3C3
- PIK3R4
- PIKFYVE
- PIP5K3
- SAC3
- TAX1BP2
- TRX
- VAC14
- VPS15
- VPS34
- ZFYVE11
|
|
Activation of Matrix Metalloproteinases
|
|
|
- C8orf57
- CATL2
- CLG
- CLG1
- CLG4A
- CLG4B
- CLGI
- CMA1
- COL18A1
- CTRB
- CTRB1
- CTRB2
- CTSG
- CTSK
- CTSL2
- CTSO
- CTSO2
- CTSU
- CTSV
- CYH
- CYM
- ELA2
- ELANE
- FUR
- FURIN
- KLK2
- KLK3
- KLKB1
- MMP1
- MMP10
- MMP11
- MMP13
- MMP14
- MMP15
- MMP16
- MMP17
- MMP2
- MMP20
- MMP24
- MMP25
- MMP3
- MMP7
- MMP8
- MMP9
- MMPL1
- MMPX2
- MPSL1
- MT4MMP
- MT5MMP
- MT6MMP
- PACE
- PCSK3
- PLG
- PRSS1
- PRSS2
- PUMP1
- SPOCK3
- STMY1
- STMY2
- STMY3
- TICN3
- TIMP
- TIMP1
- TIMP2
- TPS1
- TPS2
- TPSAB1
- TPSB1
- TRP1
- TRY1
- TRY2
- TRYP1
- TRYP2
|
|
Regulation of activated PAK-2p34 by proteasome mediated degradation
|
|
|
- C7orf76
- DSS1
- HC2
- HC3
- HC8
- HC9
- HSPC
- IFI5111
- KIAA0072
- KIAA0077
- KIAA0107
- LMP10
- LMP2
- LMP7
- LMPX
- LMPY
- MB1
- MCB1
- MECL1
- MIP224
- MOV34L
- MSS1
- NU
- PAK2
- PFAAP4
- POH1
- PROS26
- PROS27
- PROS30
- PSC2
- PSC3
- PSC5
- PSC8
- PSC9
- PSMA1
- PSMA2
- PSMA3
- PSMA4
- PSMA5
- PSMA6
- PSMA7
- PSMA7L
- PSMA8
- PSMB1
- PSMB10
- PSMB11
- PSMB2
- PSMB3
- PSMB4
- PSMB5
- PSMB5i
- PSMB6
- PSMB6i
- PSMB7
- PSMB8
- PSMB9
- PSMC1
- PSMC2
- PSMC3
- PSMC4
- PSMC5
- PSMC6
- PSMD1
- PSMD10
- PSMD11
- PSMD12
- PSMD13
- PSMD14
- PSMD2
- PSMD3
- PSMD4
- PSMD5
- PSMD6
- PSMD7
- PSMD8
- PSMD9
- PSME1
- PSME2
- PSME3
- PSME4
- PSMF1
- RING10
- RING12
- RPS27A
- SEM1
- SHFDG1
- SHFM1
- SUG1
- SUG2
- TBP1
- TBP7
- TRAP2
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
- X
- Y
- Y2
- Z
|
|
G2/M Checkpoints
|
|
|
- C7orf76
- DSS1
- GTSE1
- HC2
- HC3
- HC8
- HC9
- HSPC
- IFI5111
- KIAA0072
- KIAA0077
- KIAA0107
- LMP10
- LMP2
- LMP7
- LMPX
- LMPY
- MB1
- MCB1
- MECL1
- MIP224
- MOV34L
- MSS1
- NU
- P53
- PFAAP4
- POH1
- PROS26
- PROS27
- PROS30
- PSC2
- PSC3
- PSC5
- PSC8
- PSC9
- PSMA1
- PSMA2
- PSMA3
- PSMA4
- PSMA5
- PSMA6
- PSMA7
- PSMA7L
- PSMA8
- PSMB1
- PSMB10
- PSMB11
- PSMB2
- PSMB3
- PSMB4
- PSMB5
- PSMB5i
- PSMB6
- PSMB6i
- PSMB7
- PSMB8
- PSMB9
- PSMC1
- PSMC2
- PSMC3
- PSMC4
- PSMC5
- PSMC6
- PSMD1
- PSMD10
- PSMD11
- PSMD12
- PSMD13
- PSMD14
- PSMD2
- PSMD3
- PSMD4
- PSMD5
- PSMD6
- PSMD7
- PSMD8
- PSMD9
- PSME1
- PSME2
- PSME3
- PSME4
- PSMF1
- RING10
- RING12
- RPS27A
- SEM1
- SHFDG1
- SHFM1
- SUG1
- SUG2
- TBP1
- TBP7
- TP53
- TRAP2
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
- X
- Y
- Y2
- Z
|
|
AUF1 (hnRNP D0) binds and destabilizes mRNA
|
|
|
- C7orf76
- DSS1
- EIF4F
- EIF4G
- EIF4G1
- EIF4GI
- HC2
- HC3
- HC8
- HC9
- HSC70
- HSP27
- HSP28
- HSP72
- HSP73
- HSPA1
- HSPA10
- HSPA1A
- HSPA8
- HSPB1
- HSPC
- HSX70
- IFI5111
- KIAA0072
- KIAA0077
- KIAA0107
- LMP10
- LMP2
- LMP7
- LMPX
- LMPY
- MB1
- MCB1
- MECL1
- MIP224
- MOV34L
- MSS1
- NU
- PAB1
- PABP
- PABP1
- PABPC1
- PABPC2
- PFAAP4
- POH1
- PROS26
- PROS27
- PROS30
- PSC2
- PSC3
- PSC5
- PSC8
- PSC9
- PSMA1
- PSMA2
- PSMA3
- PSMA4
- PSMA5
- PSMA6
- PSMA7
- PSMA7L
- PSMA8
- PSMB1
- PSMB10
- PSMB11
- PSMB2
- PSMB3
- PSMB4
- PSMB5
- PSMB5i
- PSMB6
- PSMB6i
- PSMB7
- PSMB8
- PSMB9
- PSMC1
- PSMC2
- PSMC3
- PSMC4
- PSMC5
- PSMC6
- PSMD1
- PSMD10
- PSMD11
- PSMD12
- PSMD13
- PSMD14
- PSMD2
- PSMD3
- PSMD4
- PSMD5
- PSMD6
- PSMD7
- PSMD8
- PSMD9
- PSME1
- PSME2
- PSME3
- PSME4
- PSMF1
- RING10
- RING12
- RPS27A
- SEM1
- SHFDG1
- SHFM1
- SUG1
- SUG2
- TBP1
- TBP7
- TRAP2
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
- X
- Y
- Y2
- Z
|
|
Vif-mediated degradation of APOBEC3G
|
|
|
- C7orf76
- CUL5
- DSS1
- ELOB
- ELOC
- HC2
- HC3
- HC8
- HC9
- HSPC
- IFI5111
- KIAA0072
- KIAA0077
- KIAA0107
- LMP10
- LMP2
- LMP7
- LMPX
- LMPY
- MB1
- MCB1
- MECL1
- MIP224
- MOV34L
- MSS1
- NU
- PFAAP4
- POH1
- PROS26
- PROS27
- PROS30
- PSC2
- PSC3
- PSC5
- PSC8
- PSC9
- PSMA1
- PSMA2
- PSMA3
- PSMA4
- PSMA5
- PSMA6
- PSMA7
- PSMA7L
- PSMA8
- PSMB1
- PSMB10
- PSMB11
- PSMB2
- PSMB3
- PSMB4
- PSMB5
- PSMB5i
- PSMB6
- PSMB6i
- PSMB7
- PSMB8
- PSMB9
- PSMC1
- PSMC2
- PSMC3
- PSMC4
- PSMC5
- PSMC6
- PSMD1
- PSMD10
- PSMD11
- PSMD12
- PSMD13
- PSMD14
- PSMD2
- PSMD3
- PSMD4
- PSMD5
- PSMD6
- PSMD7
- PSMD8
- PSMD9
- PSME1
- PSME2
- PSME3
- PSME4
- PSMF1
- RBX1
- RING10
- RING12
- RNF75
- ROC1
- RPS27A
- SEM1
- SHFDG1
- SHFM1
- SUG1
- SUG2
- TBP1
- TBP7
- TCEB1
- TCEB2
- TRAP2
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
- VACM1
- X
- Y
- Y2
- Z
- vif
|
|
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A
|
|
|
- C7orf76
- CDC25A
- CDS1
- CHEK1
- CHEK2
- CHK1
- CHK2
- DSS1
- HC2
- HC3
- HC8
- HC9
- HSPC
- IFI5111
- KIAA0072
- KIAA0077
- KIAA0107
- LMP10
- LMP2
- LMP7
- LMPX
- LMPY
- MB1
- MCB1
- MECL1
- MIP224
- MOV34L
- MSS1
- NU
- PFAAP4
- POH1
- PROS26
- PROS27
- PROS30
- PSC2
- PSC3
- PSC5
- PSC8
- PSC9
- PSMA1
- PSMA2
- PSMA3
- PSMA4
- PSMA5
- PSMA6
- PSMA7
- PSMA7L
- PSMA8
- PSMB1
- PSMB10
- PSMB11
- PSMB2
- PSMB3
- PSMB4
- PSMB5
- PSMB5i
- PSMB6
- PSMB6i
- PSMB7
- PSMB8
- PSMB9
- PSMC1
- PSMC2
- PSMC3
- PSMC4
- PSMC5
- PSMC6
- PSMD1
- PSMD10
- PSMD11
- PSMD12
- PSMD13
- PSMD14
- PSMD2
- PSMD3
- PSMD4
- PSMD5
- PSMD6
- PSMD7
- PSMD8
- PSMD9
- PSME1
- PSME2
- PSME3
- PSME4
- PSMF1
- RAD53
- RING10
- RING12
- RPS27A
- SEM1
- SHFDG1
- SHFM1
- SUG1
- SUG2
- TBP1
- TBP7
- TRAP2
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
- X
- Y
- Y2
- Z
|
|
Cross-presentation of soluble exogenous antigens (endosomes)
|
|
|
- C7orf76
- CD207
- CLEC13D
- CLEC13DL
- CLEC13E
- CLEC4K
- DSS1
- ENDO180
- FCG1
- FCGR1
- FCGR1A
- FCGR1B
- FCGR1BP
- HC2
- HC3
- HC8
- HC9
- HSPC
- IFI5111
- IGFR1
- IGFRB
- KIAA0072
- KIAA0077
- KIAA0107
- KIAA0709
- LMP10
- LMP2
- LMP7
- LMPX
- LMPY
- MB1
- MCB1
- MECL1
- MIP224
- MOV34L
- MRC1
- MRC1L1
- MRC2
- MSS1
- NU
- PFAAP4
- POH1
- PROS26
- PROS27
- PROS30
- PSC2
- PSC3
- PSC5
- PSC8
- PSC9
- PSMA1
- PSMA2
- PSMA3
- PSMA4
- PSMA5
- PSMA6
- PSMA7
- PSMA7L
- PSMA8
- PSMB1
- PSMB10
- PSMB11
- PSMB2
- PSMB3
- PSMB4
- PSMB5
- PSMB5i
- PSMB6
- PSMB6i
- PSMB7
- PSMB8
- PSMB9
- PSMC1
- PSMC2
- PSMC3
- PSMC4
- PSMC5
- PSMC6
- PSMD1
- PSMD10
- PSMD11
- PSMD12
- PSMD13
- PSMD14
- PSMD2
- PSMD3
- PSMD4
- PSMD5
- PSMD6
- PSMD7
- PSMD8
- PSMD9
- PSME1
- PSME2
- PSME3
- PSME4
- PSMF1
- RING10
- RING12
- SEM1
- SHFDG1
- SHFM1
- SUG1
- SUG2
- TBP1
- TBP7
- TRAP2
- UPARAP
- X
- Y
- Y2
- Z
|
|
The role of GTSE1 in G2/M progression after G2 checkpoint
|
|
|
- C7orf76
- CAP20
- CCNB
- CCNB1
- CCNB2
- CDC2
- CDC28A
- CDK1
- CDKN1
- CDKN1A
- CIP1
- DIR1
- DSS1
- FKBPL
- GTSE1
- HC2
- HC3
- HC8
- HC9
- HSP90A
- HSP90AA1
- HSP90AB1
- HSP90B
- HSPC
- HSPC1
- HSPC2
- HSPC3
- HSPCA
- HSPCB
- IFI5111
- KIAA0072
- KIAA0077
- KIAA0107
- LMP10
- LMP2
- LMP7
- LMPX
- LMPY
- MAPRE1
- MB1
- MCB1
- MDA6
- MECL1
- MIP224
- MOV34L
- MSS1
- NG7
- NU
- P34CDC2
- P53
- PFAAP4
- PIC1
- PLK
- PLK1
- POH1
- PROS26
- PROS27
- PROS30
- PSC2
- PSC3
- PSC5
- PSC8
- PSC9
- PSMA1
- PSMA2
- PSMA3
- PSMA4
- PSMA5
- PSMA6
- PSMA7
- PSMA7L
- PSMA8
- PSMB1
- PSMB10
- PSMB11
- PSMB2
- PSMB3
- PSMB4
- PSMB5
- PSMB5i
- PSMB6
- PSMB6i
- PSMB7
- PSMB8
- PSMB9
- PSMC1
- PSMC2
- PSMC3
- PSMC4
- PSMC5
- PSMC6
- PSMD1
- PSMD10
- PSMD11
- PSMD12
- PSMD13
- PSMD14
- PSMD2
- PSMD3
- PSMD4
- PSMD5
- PSMD6
- PSMD7
- PSMD8
- PSMD9
- PSME1
- PSME2
- PSME3
- PSME4
- PSMF1
- RING10
- RING12
- RPS27A
- SDI1
- SEM1
- SHFDG1
- SHFM1
- SUG1
- SUG2
- TBP1
- TBP7
- TP53
- TRAP2
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
- WAF1
- X
- Y
- Y2
- Z
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Elevation of cytosolic Ca2+ levels
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- C7orf19
- CBCIP2
- CRACM1
- GOK
- INSP3R1
- ITPR1
- ITPR2
- ITPR3
- ORAI1
- ORAI2
- P2RX1
- P2RX2
- P2RX3
- P2RX4
- P2RX5
- P2RX6
- P2RX7
- P2RXL1
- P2X1
- P2X2
- P2X5
- P2X5FL
- P2X6
- STIM1
- TMEM142A
- TMEM142B
- TRP3
- TRP6
- TRP7
- TRPC3
- TRPC6
- TRPC7
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Thyroxine biosynthesis
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- C6orf71
- CGA
- DEHAL1
- DUOX
- DUOX1
- DUOX2
- IYD
- LNOX1
- LNOX2
- NIS
- SLC5A5
- THOX1
- THOX2
- TPO
- TSHB
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