RHOG GTPase cycle
|
|
|
- ANKLE2
- ARFGAP1
- ARFGAP3
- ARHG
- ARHGAP1
- ARHGAP10
- ARHGAP21
- ARHGAP32
- ARHGAP35
- ARHGAP39
- ARHGAP5
- ARHGDIA
- ARHGDIB
- ARHGDIG
- ARHGEF16
- ARHGEF26
- ARHGEF5
- BORG5
- C11orf59
- CAV
- CAV1
- CDC42
- CDC42EP1
- CDC42GAP
- CDHF5
- CED12A
- CEP1
- CG1
- CYFIP1
- DBL
- DEPDC1B
- DG6
- DIAP3
- DIAPH3
- DOCK1
- DOCK2
- DOCK3
- DOCK4
- DOCK5
- DSG2
- DUET
- DUO
- ECK
- EDMD
- ELMO2
- EMD
- EPHA2
- EPHEXIN4
- ERBB2IP
- ERBIN
- ERGIC53
- ESYT1
- F5F8D
- FAM62A
- FNRB
- GARRE1
- GDIA1
- GDIA2
- GDID4
- GRB1
- GRF1
- GRIT
- GRLF1
- HAPIP
- HSPE1
- IQGAP2
- ITGB1
- ITSN
- ITSN1
- KALRN
- KIAA0004
- KIAA0068
- KIAA0209
- KIAA0299
- KIAA0355
- KIAA0362
- KIAA0599
- KIAA0692
- KIAA0712
- KIAA0716
- KIAA0747
- KIAA1142
- KIAA1225
- KIAA1415
- KIAA1424
- KIAA1688
- KIAA1722
- KIAA1834
- KTN1
- LAMTOR1
- LAP2
- LBR
- LEM4
- LEMD3
- LETM1
- LMAN1
- MAN1
- MAP3K11
- MBC2
- MCAM
- MCF2
- MCF2L
- MDF2
- MLK3
- MOCA
- MPP7
- MSE55
- MSK12
- MUC18
- NBR
- NDUFA5
- NDUFS3
- OPHN1
- OST
- P190A
- PAK2
- PAK4
- PDRO
- PGRMC2
- PIK3R1
- PLD1
- PLEKHG3
- PMBP
- PREX1
- PTK1
- RAB7
- RAB7A
- RAP1GN1
- RHOG
- RHOGAP1
- RHOGAP5
- RICS
- SGEF
- SH3D1A
- SHMT2
- SPRK
- STA
- STB2
- STBD1
- STX5
- STX5A
- SYB3
- TFRC
- TIM
- TMPO
- TRAD
- TRIO
- VAMP3
- VANGL1
- VAPB
- VAV
- VAV1
- VAV2
- VAV3
- VRK2
- XTP8
- YKT6
- p190ARHOGAP
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Formation of apoptosome
|
|
|
- APAF1
- APIP
- AVEN
- CARD8
- CASP9
- CYC
- CYCS
- DACAR
- KIAA0413
- KIAA0955
- MCH6
- NDPP1
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|
Defective SLC6A19 causes Hartnup disorder (HND)
|
|
|
|
|
Defective SLC5A7 causes distal hereditary motor neuronopathy 7A (HMN7A)
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|
|
|
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Synthesis of PIPs in the nucleus
|
|
|
- C14orf9
- PI5P4KA
- PIP4K2A
- PIP4K2B
- PIP4K2C
- PIP4P1
- PIP5K2
- PIP5K2A
- PIP5K2B
- PIP5K2C
- TMEM55B
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|
Negative regulation of TCF-dependent signaling by DVL-interacting proteins
|
|
|
- CCDC88C
- CXXC4
- DAPLE
- DVL1
- DVL2
- DVL3
- IDAX
- KIAA0208
- KIAA1509
|
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Cargo recognition for clathrin-mediated endocytosis
|
|
|
- AAK1
- ABCC7
- ADHR
- ADRB2
- ADRB2R
- ADRBK1
- ADRBK2
- ADTAA
- ADTAB
- ADTB2
- AF1P
- AGFG1
- AGTR1
- AGTR1A
- AGTR1B
- AP17
- AP2A1
- AP2A2
- AP2B1
- AP2M1
- AP2S1
- APOB
- ARB2
- AREG
- AREGB
- ARH
- ARR1
- ARR2
- ARRB1
- ARRB2
- ARVP
- AT2R1
- AT2R1B
- AVP
- AVPR2
- B2AR
- BARK
- BARK1
- BARK2
- BTC
- CALM
- CBL
- CBL2
- CD36L2
- CD3D
- CD3G
- CD4
- CFTR
- CHRM2
- CIN85
- CLAPA1
- CLAPA2
- CLAPB1
- CLAPM1
- CLAPS2
- CLH17
- CLH22
- CLTA
- CLTB
- CLTC
- CLTCL
- CLTCL1
- CLTCL2
- CLTD
- CNSA1
- CNSA2
- CNSA3
- COPS1
- COPS2
- COPS3
- COPS4
- COPS5
- COPS6
- COPS7A
- COPS7B
- COPS8
- CSN1
- CSN2
- CSN3
- CSN4
- CSN5
- CSN6
- CSN7A
- CSN7B
- CSN8
- DA41
- DAB2
- DERP10
- DIR
- DIR3
- DOC2
- DQ1
- DQ2
- DTR
- DTS
- DVL2
- DYT1
- EGF
- EGFR
- EPGN
- EPN1
- EPN2
- EPS15
- EPS15L1
- EPS15R
- ERBB
- ERBB1
- EREG
- FCHO1
- FCHO2
- FZD4
- GLUT8
- GLUTX1
- GPS1
- GRK2
- GRK3
- HBEGF
- HBP
- HEGFL
- HER1
- HGS
- HIP9
- HRB
- HRS
- HVIP
- HYPJ
- IGF2R
- IL7R
- ITSN
- ITSN1
- ITSN2
- JAB1
- KIAA0034
- KIAA0080
- KIAA0109
- KIAA0290
- KIAA0319
- KIAA0656
- KIAA0899
- KIAA1048
- KIAA1065
- KIAA1256
- LDLR
- LDLRAP1
- LIMP2
- LIMPII
- LRP2
- M6PR
- MPR46
- MPRD
- MPRI
- N4BP4
- NECAP1
- NECAP2
- NEDD8
- NK1R
- PICALM
- PLIC1
- PLIC2
- POB1
- RAB
- REPS1
- REPS2
- RIP
- RNF55
- RPS27A
- SALF
- SBLF
- SCARB2
- SDGF
- SGIP1
- SH3D1A
- SH3D1B
- SH3D2A
- SH3D2B
- SH3D2C
- SH3GL1
- SH3GL2
- SH3GL3
- SH3KBP1
- SLC18A3
- SLC2A8
- SNAP91
- STAM
- STAM1
- STAM2
- STN1
- STN2
- STNB
- STON1
- STON2
- SVP65
- SWAP
- SYB2
- SYB3
- SYBL1
- SYT
- SYT1
- SYT11
- SYT2
- SYT8
- SYT9
- T3D
- T3G
- TA
- TAC1R
- TACR1
- TF
- TFRC
- TGFA
- TGN46
- TGN51
- TGOLN2
- TOR1A
- TOR1B
- TORA
- TRIP15
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
- UBQLN1
- UBQLN2
- V2R
- VACHT
- VAMP2
- VAMP3
- VAMP4
- VAMP7
- VAMP8
- VP
- WNT5A
|
|
tRNA modification in the mitochondrion
|
|
|
- ERAB
- GTPBP3
- HADH2
- HSD17B10
- IPT
- KIAA0391
- MOD5
- MRPP1
- MRPP2
- MRPP3
- MTGP1
- MTO1
- MTU1
- PRORP
- RG9MTD1
- SCHAD
- SDR5C1
- TRIT1
- TRMT1
- TRMT10C
- TRMT61B
- TRMU
- XH98G2
|
|
SUMOylation of DNA methylation proteins
|
|
|
- AIM
- BAP1
- BMI1
- CBX2
- CBX4
- CBX8
- CXXC9
- DING
- DNMT
- DNMT1
- DNMT3A
- DNMT3B
- EDR1
- EDR2
- EDR3
- HIPI3
- MEL18
- PC3
- PCGF2
- PCGF4
- PH1
- PH2
- PH3
- PHC1
- PHC2
- PHC3
- RC1
- RING1
- RING1A
- RING1B
- RNF1
- RNF110
- RNF2
- RNF51
- SMT3C
- SMT3H3
- SUMO1
- UBC9
- UBCE9
- UBE2I
- UBL1
- ZNF144
|
|
Regulation of HSF1-mediated heat shock response
|
|
|
- AAAS
- AAG2
- ADRACALA
- APG1
- APG2
- AROS
- ATM
- ATR
- BAG1
- BAG2
- BAG3
- BAG4
- BAG5
- BIS
- C11orf73
- C20orf60
- C7orf14
- CAIN
- CAN
- CCAR2
- CG1
- D3S1231E
- DBC1
- DNAJ1
- DNAJB1
- DNAJB6
- DNAJC2
- DNAJC7
- ERK1
- ERK2
- FAM10A1
- FRP1
- GRP75
- GRP78
- GSK3B
- HAP
- HDJ1
- HIKESHI
- HIP
- HSC70
- HSF1
- HSJ2
- HSP105
- HSP110
- HSP60
- HSP70B
- HSP70B'
- HSP70L1
- HSP72
- HSP73
- HSPA1
- HSPA10
- HSPA12A
- HSPA12B
- HSPA13
- HSPA14
- HSPA1A
- HSPA1B
- HSPA1L
- HSPA2
- HSPA4
- HSPA4L
- HSPA5
- HSPA6
- HSPA7
- HSPA8
- HSPA9
- HSPA9B
- HSPF1
- HSPH1
- HSPH2
- HSPH3
- HSTF1
- HSX70
- KIAA0023
- KIAA0095
- KIAA0169
- KIAA0197
- KIAA0201
- KIAA0225
- KIAA0417
- KIAA0618
- KIAA0791
- KIAA0873
- KIAA0906
- KIAA1967
- MAPK1
- MAPK3
- MAPKAPK2
- MP44
- MPHOSPH11
- MPP11
- MRJ
- MRNP41
- MSJ1
- NDC1
- NPAP60L
- NUP107
- NUP120
- NUP121
- NUP133
- NUP153
- NUP155
- NUP160
- NUP188
- NUP205
- NUP210
- NUP214
- NUP35
- NUP358
- NUP37
- NUP42
- NUP43
- NUP50
- NUP53
- NUP54
- NUP62
- NUP75
- NUP85
- NUP88
- NUP93
- NUPL2
- OSP94
- PCNT1
- POM121
- POM121A
- POM121C
- PRKM1
- PRKM2
- PRKM3
- RAE1
- RANBP2
- REPA1
- REPA2
- REPA3
- RPA1
- RPA14
- RPA2
- RPA3
- RPA32
- RPA34
- RPA70
- RPS19BP1
- SEC13
- SEC13A
- SEC13L1
- SEC13R
- SIR2L1
- SIRT1
- SNC6
- SODD
- ST13
- STCH
- TMEM48
- TPR
- TPR2
- TTC2
- YWHAE
- ZRF1
- mt-HSP70
|
|
TYSND1 cleaves peroxisomal proteins
|
|
|
- ACAA
- ACAA1
- ACOX
- ACOX1
- AGPS
- EDH17B4
- HSD17B4
- PAHX
- PHYH
- PTHIO
- SCP2
- SDR8C1
- TYSND1
|
|
Defective SLC33A1 causes spastic paraplegia 42 (SPG42)
|
|
|
|
|
HSF1 activation
|
|
|
- EEF1A
- EEF1A1
- EF1A
- HDAC6
- HEL-220
- HEL-S-70
- HSBP1
- HSF1
- HSF1BP
- HSP90A
- HSP90AA1
- HSP90AB1
- HSP90B
- HSPC1
- HSPC2
- HSPC3
- HSPCA
- HSPCB
- HSTF1
- KIAA0901
- LENG7
- P23
- PTGES3
- REPA1
- REPA2
- REPA3
- RPA1
- RPA14
- RPA2
- RPA3
- RPA32
- RPA34
- RPA70
- TEBP
- VCP
- YWHAE
|
|
Reactions specific to the hybrid N-glycan synthesis pathway
|
|
|
|
|
Toxicity of botulinum toxin type D (botD)
|
|
|
- KIAA0735
- KIAA0736
- KIAA1054
- SV2A
- SV2B
- SV2C
- SYB1
- SYB2
- VAMP1
- VAMP2
- botD
|
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Sulfur amino acid metabolism
|
|
|
- AHCY
- AMS1
- BHMT
- BHMT2
- MAT1A
- MATA1
- MTR
- MTRR
- SAHH
|
|
Downregulation of ERBB2 signaling
|
|
|
- BDP1
- BTC
- CDC37
- CDC37A
- CHIP
- CTK
- CUL5
- DTR
- DTS
- EGF
- EGFR
- ERBB
- ERBB1
- ERBB2
- ERBB2IP
- ERBIN
- EREG
- GGF
- HBEGF
- HEGFL
- HER1
- HER2
- HGL
- HRGA
- HSP90A
- HSP90AA1
- HSPC1
- HSPCA
- HYL
- KIAA1225
- LAP2
- MATK
- MLN19
- NDF
- NEU
- NGL
- NRG1
- NRG2
- NRG3
- NRG4
- NTAK
- PTPN12
- PTPN18
- RPS27A
- SMDF
- STUB1
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
- VACM1
|
|
Peroxisomal protein import
|
- 2-Hydroxyacid oxidase 1
- 2-Hydroxyacid oxidase 2
- 2-hydroxyacyl-CoA lyase 1
- 3-ketoacyl-CoA thiolase, peroxisomal
- AN1-type zinc finger protein 6
- Acyl-coenzyme A diphosphatase NUDT19
- Acyl-coenzyme A thioesterase 2, mitochondrial
- Acyl-coenzyme A thioesterase 8
- Alanine--glyoxylate aminotransferase
- Alkyldihydroxyacetonephosphate synthase, peroxisomal
- Alpha-methylacyl-CoA racemase
- Bifunctional epoxide hydrolase 2
- Bile acid-CoA
- Carnitine O-acetyltransferase
- Catalase
- D-amino-acid oxidase
- D-aspartate oxidase
- Dehydrogenase/reductase SDR family member 4
- Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial
- Dihydroxyacetone phosphate acyltransferase
- Glutathione S-transferase kappa 1
- Hydroxymethylglutaryl-CoA lyase, mitochondrial
- Insulin-degrading enzyme
- Isocitrate dehydrogenase [NADP] cytoplasmic
- Lon protease homolog 2, peroxisomal
- Long-chain fatty acid transport protein 2
- Nitric oxide synthase, inducible
- Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]
- Peroxisomal ATPase PEX1
- Peroxisomal ATPase PEX6
- Peroxisomal N(1)-acetyl-spermine/spermidine oxidase
- Peroxisomal acyl-coenzyme A oxidase 1
- Peroxisomal acyl-coenzyme A oxidase 2
- Peroxisomal acyl-coenzyme A oxidase 3
- Peroxisomal bifunctional enzyme
- Peroxisomal carnitine O-octanoyltransferase
- Peroxisomal coenzyme A diphosphatase NUDT7
- Peroxisomal leader peptide-processing protease
- Peroxisomal membrane protein PEX13
- Peroxisomal membrane protein PEX14
- Peroxisomal multifunctional enzyme type 2
- Peroxisomal sarcosine oxidase
- Peroxisomal succinyl-coenzyme A thioesterase
- Peroxisomal targeting signal 2 receptor
- Peroxisomal trans-2-enoyl-CoA reductase
- Peroxisome assembly protein 12
- Peroxisome assembly protein 26
- Peroxisome biogenesis factor 10
- Peroxisome biogenesis factor 2
- Phytanoyl-CoA dioxygenase, peroxisomal
- Polyubiquitin-B
- Polyubiquitin-C
- Protein Mpv17
- Sterol carrier protein 2
- Ubiquitin carboxyl-terminal hydrolase 9X
- Ubiquitin-conjugating enzyme E2 D1
- Ubiquitin-conjugating enzyme E2 D2
- Ubiquitin-conjugating enzyme E2 D3
- Ubiquitin-ribosomal protein eL40 fusion protein
- Ubiquitin-ribosomal protein eS31 fusion protein
|
|
- ACAA
- ACAA1
- ACOT2
- ACOT4
- ACOT8
- ACOX
- ACOX1
- ACOX2
- ACOX3
- ACSVL1
- ACTEIII
- AGPS
- AGT1
- AGXT
- AMACR
- AWP1
- BAAT
- BRCOX
- CAT
- CAT1
- COT
- CRAT
- CROT
- DAMOX
- DAO
- DAPAT
- DDO
- DECR2
- DFFRX
- DHAPAT
- DHRS4
- ECH1
- ECHD
- EDH17B4
- EHHADH
- EPHX2
- FACVL1
- FAM
- FATP2
- GNPAT
- GOX1
- GSTK1
- HACL1
- HAO1
- HAO2
- HAOX2
- HMGCL
- HPCL
- HPCL2
- HSD17B4
- IDE
- IDH1
- LONP
- LONP2
- LPIPOX
- MPV17
- NOS2
- NOS2A
- NUDT19
- NUDT7
- PAF1
- PAF3
- PAHX
- PAO
- PAOX
- PDCR
- PECR
- PEX1
- PEX10
- PEX12
- PEX13
- PEX14
- PEX2
- PEX26
- PEX6
- PEX7
- PHYH
- PHYH2
- PICD
- PIPOX
- PMP3
- PMP35
- PRCOX
- PSO
- PTE1
- PTE2
- PTE2A
- PTE2B
- PTEIB
- PTHIO
- PTS2R
- PUBC1
- PXAAA1
- PXMP3
- RNF69
- RNF72
- RPS27A
- SCP2
- SDR17C1
- SDR25C2
- SDR29C1
- SDR8C1
- SFT
- SLC27A2
- SPAT
- TYSND1
- UBA52
- UBA80
- UBB
- UBC
- UBC4
- UBC5A
- UBC5B
- UBC5C
- UBCEP1
- UBCEP2
- UBCH4
- UBCH5
- UBCH5A
- UBCH5B
- UBCH5C
- UBE2D1
- UBE2D2
- UBE2D3
- USP9
- USP9X
- VLACS
- ZA20D3
- ZFAND6
|
|
Replication of the SARS-CoV-1 genome
|
|
|
- 1a
- DDX5
- G17P1
- HELR
- HLR1
- RB1
- VHL
- ZCRB1
- rep
|
|
RHOT2 GTPase cycle
|
|
|
- ALS2CR3
- ARHT2
- C16orf39
- CPRP1
- KIAA0214
- KIAA0549
- KIAA1042
- MFN1
- MFN2
- MYO19
- MYOHD1
- OIP106
- RAP1GDS1
- RHOT2
- SMGGDS
- TRAK1
- TRAK2
|
|
BMAL1:CLOCK,NPAS2 activates circadian gene expression
|
|
|
- AIB3
- ARC205
- ARNTL
- ARNTL2
- ARVP
- AVP
- BAF60C
- BHLHB2
- BHLHB3
- BHLHE40
- BHLHE41
- BHLHE5
- BHLHE6
- BHLHE74
- BHLHE75
- BHLHE8
- BHLHE9
- BMAL1
- BMAL2
- CARM1
- CBP
- CCR4
- CCRN4L
- CHD9
- CLIF
- CLOCK
- CREBBP
- CRSP1
- CRSP200
- DBP
- DEC1
- DEC2
- DRIP205
- DRIP230
- F7
- HCA137
- HELZ2
- IRA1
- KIAA0181
- KIAA0308
- KIAA0334
- KIAA1769
- KISH2
- KKLF
- KLF15
- MED1
- MOP3
- MOP4
- MOP9
- NAMPT
- NCOA1
- NCOA2
- NCOA6
- NCOA6IP
- NOC
- NOCT
- NPAS2
- NR1C1
- NR2B1
- PAI1
- PASD3
- PASD4
- PASD9
- PBEF
- PBEF1
- PBP
- PIMT
- PLANH1
- PPAR
- PPARA
- PPARBP
- PPARGBP
- PRIC285
- PRIC320
- PRMT4
- RAP250
- RB18A
- RXRA
- SERPINE1
- SHARP1
- SHARP2
- SMARCD3
- SRC1
- SRC2
- STRA13
- TBL1
- TBL1X
- TBL1XR1
- TBLR1
- TGS1
- TIF2
- TRAP220
- TRBP
- TRIP2
- VP
|
|
Glyoxylate metabolism and glycine degradation
|
|
|
- AGT1
- AGT2
- AGXT
- AGXT2
- ALDH4
- ALDH4A1
- C10orf65
- DAMOX
- DAO
- DDO
- DHDPSL
- GLXR
- GNMT
- GOT2
- GOX1
- GRHPR
- HAO1
- HOGA1
- HSPOX1
- HYPDH
- KYAT4
- P5CDH
- PMP22
- PRODH2
- PXMP2
- SPAT
|
|
MPS I - Hurler syndrome
|
|
|
|
|
Regulation of IFNG signaling
|
|
|
- CIS3
- DDXBP1
- HCP
- IFNG
- IFNGR1
- IFNGR2
- IFNGT1
- JAK1
- JAK1A
- JAK1B
- JAK2
- PIAS1
- PTP1B
- PTP1C
- PTP2C
- PTPN1
- PTPN11
- PTPN6
- SHPTP2
- SMT3C
- SMT3H3
- SOCS1
- SOCS3
- SSI1
- SSI3
- SUMO1
- TIP3
- UBL1
|
|
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1
|
|
|
- BARA
- BMYB
- C14orf46
- CCN1
- CCNA
- CCNA2
- CDC2
- CDC28A
- CDK1
- CDKN1
- CXCDC1
- DP1
- DP2
- E2F1
- E2F4
- E2F5
- HDAC1
- KIAA2037
- LIN37
- LIN52
- LIN54
- LIN9
- MYBL2
- P34CDC2
- RB2
- RBAP48
- RBBP3
- RBBP4
- RBL1
- RBL2
- RPD3L1
- TFDP1
- TFDP2
- TGS
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