NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
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- CASP10
- CASP8
- CHUK
- DDX58
- EFP
- FADD
- FIP3
- IFIH1
- IKBKB
- IKBKG
- IKKA
- IKKB
- IPS1
- KIAA1271
- MAVS
- MCH4
- MCH5
- MDA5
- MORT1
- NEMO
- RH116
- RIGI
- RIP
- RIP1
- RIPK1
- RNF135
- RNF147
- RNF87
- TCF16
- TRIM25
- TRIM4
- VISA
- ZNF147
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TRAF6 mediated NF-kB activation
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- A4
- AD1
- AGER
- APP
- CHUK
- DDX58
- EFP
- FIP3
- HMG1
- HMGB1
- IFIH1
- IKBA
- IKBB
- IKBKB
- IKBKG
- IKKA
- IKKB
- IPS1
- KBRAS1
- KBRAS2
- KIAA1271
- LYT10
- MAD3
- MAP3K1
- MAPKKK1
- MAVS
- MDA5
- MEKK
- MEKK1
- NEMO
- NFKB1
- NFKB2
- NFKB3
- NFKBI
- NFKBIA
- NFKBIB
- NKIRAS1
- NKIRAS2
- RAGE
- RELA
- RH116
- RIGI
- RNF135
- RNF147
- RNF85
- RNF87
- S100A12
- S100B
- SAA1
- TCF16
- TRAF2
- TRAF6
- TRAP3
- TRIM25
- TRIM4
- TRIP9
- VISA
- ZNF147
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Regulation of TNFR1 signaling
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- API1
- API2
- API3
- BIRC2
- BIRC3
- BIRC4
- C20orf18
- CASP8
- CHIP
- CHUK
- CLIP3
- CLIPR59
- CYLD
- CYLD1
- DUBA7
- EBI6
- FADD
- FAM105B
- FIP2
- FIP3
- GLC1E
- GNB2L1
- HIP7
- HYPL
- IAP3
- IKBKB
- IKBKE
- IKBKG
- IKKA
- IKKB
- IKKE
- IKKI
- IMP3
- IMP4
- KIAA0151
- KIAA0722
- KIAA0757
- KIAA0849
- KIAA1532
- MAPKAPK2
- MCH5
- MIB2
- MIHB
- MIHC
- MORT1
- NAK
- NEMO
- NRP
- OPG199
- OPTN
- OTDC1
- OTUD1
- OTUD7B
- OTUD7C
- OTULIN
- PD1
- PSL1
- PSL2
- PUBC1
- RACK1
- RBCK1
- RIP
- RIP1
- RIPK1
- RNF31
- RNF48
- RNF49
- RNF54
- RPS27A
- SFT
- SHARPIN
- SIPL1
- SKD
- SPATA2
- SPI-2
- SPPL2A
- SPPL2B
- STUB1
- T6BP
- TAX1BP1
- TBK1
- TCF16
- TNF
- TNFA
- TNFAIP3
- TNFAR
- TNFR1
- TNFRSF1A
- TNFSF2
- TRADD
- TRAF1
- TRAF2
- TRAP3
- UBA52
- UBA80
- UBB
- UBC
- UBC4
- UBC5A
- UBC5B
- UBC5C
- UBCE7
- UBCE7IP3
- UBCEP1
- UBCEP2
- UBCH4
- UBCH5
- UBCH5A
- UBCH5B
- UBCH5C
- UBCH7
- UBE2D1
- UBE2D2
- UBE2D3
- UBE2L3
- UBP41
- UL36
- ULK1
- UNP
- UNPH
- USP2
- USP21
- USP23
- USP4
- XAP3
- XAP4
- XIAP
- ZA20D1
- ZIBRA
- ZZANK1
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Regulation of NF-kappa B signaling
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- CASP8
- CHUK
- FIP3
- IKBIP
- IKBKB
- IKBKG
- IKIP
- IKKA
- IKKB
- ISG43
- KIAA0014
- KIAA0615
- LRRC14
- MCH5
- N4BP1
- NEMO
- NLRC5
- NLRX1
- NOD27
- NOD4
- NOD5
- NOD9
- P53
- RNF85
- RPS27A
- TCF16
- TGT
- TP53
- TRAF2
- TRAF6
- TRAP3
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
- USP14
- USP18
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TNFR1-induced NF-kappa-B signaling pathway
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- API1
- API2
- API3
- BIRC2
- BIRC3
- BIRC4
- C20orf18
- CHUK
- CYLD
- CYLD1
- DUBA7
- EBI6
- FIP2
- FIP3
- GLC1E
- GNB2L1
- HIP7
- HYPL
- IAP3
- IKBKB
- IKBKG
- IKKA
- IKKB
- KIAA0733
- KIAA0757
- KIAA0849
- MAP3K7
- MAP3K7IP1
- MAP3K7IP2
- MAP3K7IP3
- MIHB
- MIHC
- NEMO
- NRP
- OPTN
- OTDC1
- OTUD1
- OTUD7B
- OTUD7C
- PD1
- RACK1
- RBCK1
- RIP
- RIP1
- RIPK1
- RNF31
- RNF48
- RNF49
- RNF54
- SHARPIN
- SIPL1
- SPATA2
- TAB1
- TAB2
- TAB3
- TAK1
- TCF16
- TNF
- TNFA
- TNFAIP3
- TNFAR
- TNFR1
- TNFRSF1A
- TNFSF2
- TRADD
- TRAF1
- TRAF2
- TRAP3
- UBCE7IP3
- UBP41
- UNP
- UNPH
- USP2
- USP21
- USP23
- USP4
- XAP3
- XAP4
- XIAP
- ZA20D1
- ZIBRA
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TAK1-dependent IKK and NF-kappa-B activation
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- A4
- AD1
- AGER
- ALPK1
- APP
- BLU
- CARD15
- CARD4
- CARDIAK
- CHUK
- CROC1
- FIP3
- HMG1
- HMGB1
- IKBA
- IKBB
- IKBKB
- IKBKG
- IKKA
- IKKB
- IRAK
- IRAK1
- IRAK2
- ISG43
- KBRAS1
- KBRAS2
- KIAA0733
- KIAA1527
- LAK
- LYT10
- MAD3
- MAP3K7
- MAP3K7IP1
- MAP3K7IP2
- MAP3K7IP3
- N
- NEMO
- NFKB1
- NFKB2
- NFKB3
- NFKBI
- NFKBIA
- NFKBIB
- NKIRAS1
- NKIRAS2
- NOD1
- NOD2
- RAGE
- RELA
- RICK
- RIP2
- RIPK2
- RNF85
- RPS27A
- S100A12
- S100B
- SAA1
- T2BP
- TAB1
- TAB2
- TAB3
- TAK1
- TCF16
- TIFA
- TRAF6
- TRIP9
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
- UBE2N
- UBE2V
- UBE2V1
- UEV1
- USP18
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RIP-mediated NFkB activation via ZBP1
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- C20orf183
- CHUK
- DDX9
- DHX9
- DLM1
- FIP3
- IKBA
- IKBB
- IKBKB
- IKBKG
- IKKA
- IKKB
- KBRAS1
- KBRAS2
- LKP
- LYT10
- MAD3
- MYD88
- NDH2
- NEMO
- NFKB1
- NFKB2
- NFKB3
- NFKBI
- NFKBIA
- NFKBIB
- NKIRAS1
- NKIRAS2
- PRVTIRB
- RELA
- RIP
- RIP1
- RIP3
- RIPK1
- RIPK3
- TCF16
- TICAM1
- TLR3
- TRIF
- TRIP9
- ZBP1
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TICAM1, RIP1-mediated IKK complex recruitment
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- API1
- API2
- BIRC2
- BIRC3
- BLU
- CHUK
- CROC1
- FIP3
- IKBKB
- IKBKG
- IKKA
- IKKB
- MIHB
- MIHC
- NEMO
- PRVTIRB
- PUBC1
- RIP
- RIP1
- RIP3
- RIPK1
- RIPK3
- RNF48
- RNF49
- RNF85
- RPS27A
- SFT
- TCF16
- TICAM1
- TLR3
- TRAF6
- TRIF
- UBA52
- UBA80
- UBB
- UBC
- UBC4
- UBC5A
- UBC5B
- UBC5C
- UBCEP1
- UBCEP2
- UBCH4
- UBCH5
- UBCH5A
- UBCH5B
- UBCH5C
- UBE2D1
- UBE2D2
- UBE2D3
- UBE2N
- UBE2V
- UBE2V1
- UEV1
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NOD1/2 Signaling Pathway
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- AAMP
- API1
- API2
- BIRC2
- BIRC3
- BLU
- CARD15
- CARD4
- CARD9
- CARDIAK
- CASP1
- CASP2
- CASP4
- CASP8
- CASP9
- CHUK
- CROC1
- CSBP
- CSBP1
- CSBP2
- CSPB1
- CYLD
- CYLD1
- ERK6
- FIP3
- ICH1
- ICH2
- IKBKB
- IKBKG
- IKKA
- IKKB
- IL1BC
- IL1BCE
- IRAK
- IRAK1
- IRAK2
- ITCH
- KIAA0733
- KIAA0849
- MAP2K6
- MAP3K7
- MAP3K7IP1
- MAP3K7IP2
- MAP3K7IP3
- MAPK11
- MAPK12
- MAPK13
- MAPK14
- MCH5
- MCH6
- MEK6
- MIHB
- MIHC
- MKK6
- MXI2
- N
- NEDD2
- NEMO
- NOD1
- NOD2
- OTUD7C
- PRKM11
- PRKM13
- PRKMK6
- RICK
- RIP2
- RIPK2
- RNF48
- RNF49
- RNF85
- SAPK2
- SAPK2A
- SAPK2B
- SAPK3
- SAPK4
- SKK3
- TAB1
- TAB2
- TAB3
- TAK1
- TCF16
- TNFAIP3
- TRAF6
- UBE2N
- UBE2V
- UBE2V1
- UEV1
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Assembly and cell surface presentation of NMDA receptors
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- ACTN2
- APBA1
- BCL8B
- CAM2
- CAMK
- CAMK-II
- CAMK2
- CAMK2A
- CAMK2B
- CAMK2D
- CAMK2G
- CAMKA
- CAMKB
- CAMKD
- CAMKG
- CASK
- DLG1
- DLG2
- DLG3
- DLG4
- GRIN1
- GRIN2A
- GRIN2B
- GRIN2C
- GRIN2D
- GRIN3A
- GRIN3B
- GluN2D
- KIAA0968
- KIAA1232
- KIAA1365
- KIAA1405
- KIAA1544
- KIAA1973
- KIF17
- KIF3X
- LAP1
- LIN2
- LIN7A
- LIN7B
- LIN7C
- LRRC7
- LYST2
- MALS1
- MALS2
- MALS3
- MINT1
- NBEA
- NEFL
- NF68
- NFL
- NMDAR1
- NMDAR2A
- NMDAR2B
- NMDAR2C
- NMDAR2D
- PSD95
- VELI1
- VELI2
- VELI3
- X11
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FGFR1c ligand binding and activation
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- ADMLX
- ANOS1
- C19orf3
- FGF1
- FGF2
- FGF20
- FGF23
- FGF4
- FGF6
- FGF9
- FGFA
- FGFB
- GIPC
- GIPC1
- HST
- HST2
- HSTF1
- HSTF2
- HYPF
- KAL
- KAL1
- KALIG1
- KS3
- RGS19IP1
- TGFBR3
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FGFR1b ligand binding and activation
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- C19orf3
- FGF1
- FGF10
- FGF2
- FGF22
- FGF3
- FGFA
- FGFB
- GIPC
- GIPC1
- INT2
- RGS19IP1
- TGFBR3
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RHO GTPases Activate Rhotekin and Rhophilins
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- ARH12
- ARH6
- ARH9
- ARHA
- ARHB
- ARHC
- KIAA1929
- LIN7B
- MALS2
- RHO12
- RHOA
- RHOB
- RHOC
- RHPN1
- RHPN2
- ROPN1
- ROPN1A
- RTKN
- RTKN1
- TAX1BP3
- TIP1
- VELI2
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Negative regulation of TCF-dependent signaling by WNT ligand antagonists
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- DKK1
- DKK2
- DKK4
- FRP
- FRP1
- FRP2
- KREMEN
- KREMEN1
- KREMEN2
- KRM1
- KRM2
- LR3
- LRP5
- LRP6
- LRP7
- SARP1
- SARP2
- SFRP1
- SFRP2
- SOST
- WIF1
- WNT14
- WNT3A
- WNT4
- WNT5A
- WNT9A
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SARS-CoV-2 modulates host translation machinery
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- CCG2
- COD
- D6S218E
- DDX20
- DP103
- FAM51A1
- FAU
- FTE1
- GEMIN2
- GEMIN3
- GEMIN4
- GEMIN5
- GEMIN6
- GEMIN7
- GEMIN8
- LAMBR
- LAMR1
- MFTL
- MPS1
- PBSCF
- PBSCG
- RIG
- RPS10
- RPS11
- RPS12
- RPS13
- RPS14
- RPS15
- RPS15A
- RPS16
- RPS17
- RPS17L
- RPS18
- RPS19
- RPS2
- RPS20
- RPS21
- RPS23
- RPS24
- RPS25
- RPS26
- RPS27
- RPS27A
- RPS27L
- RPS28
- RPS29
- RPS3
- RPS3A
- RPS4
- RPS4X
- RPS4Y
- RPS4Y1
- RPS4Y2
- RPS4Y2P
- RPS5
- RPS6
- RPS7
- RPS8
- RPS9
- RPSA
- SCAR
- SIP1
- SMN
- SMN1
- SMN2
- SMNC
- SMNT
- SNRPB
- SNRPB1
- SNRPD1
- SNRPD2
- SNRPD3
- SNRPE
- SNRPF
- SNRPG
- UBA80
- UBCEP1
- rep
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Glutathione conjugation
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- AKR1A1
- ALDR1
- ALR
- ESD
- FAEES3
- GST1
- GST12
- GST2
- GST3
- GST4
- GST5
- GSTA1
- GSTA2
- GSTA3
- GSTA4
- GSTA5
- GSTK1
- GSTM1
- GSTM2
- GSTM3
- GSTM4
- GSTM5
- GSTO1
- GSTO2
- GSTP1
- GSTS
- GSTT1
- GSTT2
- GSTT2B
- GSTTLP28
- GSTZ1
- HPGDS
- MAAI
- MGST
- MGST1
- MGST2
- MGST3
- PGDS
- PTGDS2
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Branched-chain amino acid catabolism
|
- 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial
- 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial
- 3-hydroxyacyl-CoA dehydrogenase type-2
- 3-hydroxyisobutyrate dehydrogenase, mitochondrial
- 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial
- Acetyl-CoA acetyltransferase, mitochondrial
- Branched-chain alpha-ketoacid dehydrogenase kinase
- Branched-chain-amino-acid aminotransferase, cytosolic
- Branched-chain-amino-acid aminotransferase, mitochondrial
- Dihydrolipoyl dehydrogenase, mitochondrial
- Enoyl-CoA hydratase, mitochondrial
- Isobutyryl-CoA dehydrogenase, mitochondrial
- Isovaleryl-CoA dehydrogenase, mitochondrial
- Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial
- Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial
- Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial
- Methylglutaconyl-CoA hydratase, mitochondrial
- Methylmalonate-semialdehyde/malonate-semialdehyde dehydrogenase [acylating], mitochondrial
- Protein phosphatase Mn(2+)-dependent 1K
- Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial
- Solute carrier family 25 member 44
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- ACAD8
- ACADSB
- ACAT
- ACAT1
- ALDH6A1
- ARC42
- AUH
- BCAT1
- BCAT2
- BCATE2
- BCATM
- BCKDHA
- BCKDHB
- BCKDHE2
- BCKDK
- BCT1
- BCT2
- DBT
- DLD
- ECA39
- ECA40
- ECHS1
- ERAB
- GCSL
- HADH2
- HIBADH
- HIBCH
- HSD17B10
- IBD
- IVD
- KIAA0446
- LAD
- MAT
- MCCA
- MCCB
- MCCC1
- MCCC2
- MMSDH
- MRPP2
- PHE3
- PP2CM
- PPM1K
- SCHAD
- SDR5C1
- SLC25A44
- XH98G2
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Regulation of BACH1 activity
|
|
|
- BACH1
- CUL1
- EMC19
- FBL17
- FBX13
- FBXL1
- FBXL17
- FBXO13
- MAFK
- OCP2
- RBX1
- RNF75
- ROC1
- RPS27A
- SKP1
- SKP1A
- SKP2
- TCEB1L
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
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Regulation of HMOX1 expression and activity
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|
- BACH1
- H13
- HM13
- HMOX1
- HO
- HO1
- IMP1
- MAFK
- NFE2L2
- NRF2
- PSL3
- SPP
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NFE2L2 regulating anti-oxidant/detoxification enzymes
|
|
|
- ATF4
- BACH1
- C20orf139
- CBP
- CREB2
- CREBBP
- DIA4
- EP300
- GCLC
- GCLM
- GLCL
- GLCLC
- GLCLR
- GRIM12
- GSTA1
- GSTA3
- HMOX1
- HO
- HO1
- KDRF
- MAFK
- NFE2L2
- NMOR1
- NQO1
- NRF2
- P300
- PAGA
- PAGB
- PRDX1
- SLC7A11
- SOD3
- SRX
- SRX1
- SRXN1
- TDPX2
- TRDX
- TRX
- TRX1
- TXN
- TXNRD1
- TXREB
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Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
|
|
|
- ADCP2
- AN2
- CD26
- DPP4
- FFAR1
- GATA4
- GIP
- GPR119
- GPR40
- ISL1
- KIAA0102
- NEC1
- PAX6
- PCSK1
- SEC11A
- SEC11C
- SEC11L1
- SEC11L3
- SPC12
- SPC18
- SPC21
- SPC22
- SPC25
- SPCS1
- SPCS2
- SPCS3
- SPCS4A
- SPCS4C
|
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Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion
|
|
|
- FFAR1
- GA11
- GAQ
- GNA11
- GNA14
- GNA15
- GNA16
- GNAQ
- GPR40
- KIAA0581
- PLCB1
- PLCB2
- PLCB3
|
|
Defective OPLAH causes OPLAHD
|
|
|
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|
Alpha-oxidation of phytanate
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|
|
- ACSVL1
- FACVL1
- FATP2
- HACL1
- HPCL
- HPCL2
- PAHX
- PECR
- PHYH
- PHYH2
- PMP34
- SDR29C1
- SLC25A17
- SLC27A2
- VLACS
|
|
Inactivation, recovery and regulation of the phototransduction cascade
|
|
|
- C2orf34
- C6orf131
- CALM
- CALM1
- CAM
- CAM1
- CAMKMT
- CLNMT
- CNCG
- CNCG1
- CNCG2
- CNCG3L
- CNCG4
- CNGA1
- CNGB1
- CORD6
- FNTA
- FNTB
- GCAP
- GCAP1
- GCAP2
- GCAP3
- GNAT1
- GNATR
- GNB1
- GNGT1
- GPRK7
- GRK1
- GRK7
- GUC1A4
- GUC2D
- GUC2F
- GUCA1
- GUCA1A
- GUCA1B
- GUCA1C
- GUCY2D
- GUCY2F
- KIAA0094
- METAP1
- METAP2
- MNPEP
- NMT
- NMT1
- NMT2
- OPN2
- P67EIF2
- PDE6A
- PDE6B
- PDE6G
- PDEA
- PDEB
- PDEG
- PKCA
- PPEF
- PPEF1
- PPP7C
- PRKACA
- PRKCA
- PRKCQ
- PRKCT
- R9AP
- RCNC2
- RCV1
- RCVRN
- RETGC
- RETGC1
- RETGC2
- RGS9BP
- RHO
- RHOK
- SAG
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