GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **1126 - 1150** of **2090** in total

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Pathway Name ▲	Protein Name	UniProt ID	Gene Symbol	Organism
NOTCH1 Intracellular Domain Regulates Transcription	CREB-binding protein Cullin-1 Cyclin-C Cyclin-dependent kinase 8 E3 ubiquitin-protein ligase RBX1 F-box-like/WD repeat-containing protein TBL1X F-box-like/WD repeat-containing protein TBL1XR1 Hairy/enhancer-of-split related with YRPW motif protein 1 Hairy/enhancer-of-split related with YRPW motif protein 2 Hairy/enhancer-of-split related with YRPW motif-like protein Histone acetyltransferase KAT2A Histone acetyltransferase KAT2B Histone acetyltransferase p300 Histone deacetylase 11 Histone deacetylase 1 Histone deacetylase 2 Histone deacetylase 3 Histone deacetylase 4 Histone deacetylase 5 Histone deacetylase 6 Histone deacetylase 7 Histone deacetylase 8 Histone deacetylase 9 Hypoxia-inducible factor 1-alpha Mastermind-like domain-containing protein 1 Mastermind-like protein 1 Mastermind-like protein 2 Mastermind-like protein 3 Myc proto-oncogene protein Neurobeachin Neurogenic locus notch homolog protein 1 Nuclear receptor corepressor 1 Nuclear receptor corepressor 2 Polyamine deacetylase HDAC10 Polyubiquitin-B Polyubiquitin-C Recombining binding protein suppressor of hairless S-phase kinase-associated protein 1 SNW domain-containing protein 1 Transcription factor HES-1 Transcription factor HES-5 Transducin-like enhancer protein 1 Transducin-like enhancer protein 2 Transducin-like enhancer protein 4 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O15379 O60907 O75376 P01106 P0CG47 P0CG48 P24863 P46531 P49336 P56524 P62877 P62979 P62987 P63208 Q04724 Q04725 Q04727 Q06330 Q09472 Q13495 Q13547 Q13573 Q13616 Q14469 Q16665 Q5TA89 Q8IZL2 Q8NFP9 Q8WUI4 Q92585 Q92769 Q92793 Q92830 Q92831 Q969S8 Q96DB2 Q96JK9 Q9BY41 Q9BZK7 Q9NQ87 Q9UBN7 Q9UBP5 Q9UKV0 Q9UQL6 Q9Y5J3 Q9Y618	BCL8B BHLHB31 BHLHB32 BHLHB33 BHLHB38 BHLHB39 BHLHE39 BHLHE78 CBP CCNC CDK8 CG1 CHF1 CHF2 CREBBP CTG26 CUL1 CXorf6 EMC19 EP300 GCN5 GCN5L2 GRG4 GRL HDAC1 HDAC10 HDAC11 HDAC2 HDAC3 HDAC4 HDAC5 HDAC6 HDAC7 HDAC7A HDAC7B HDAC8 HDAC9 HDACL1 HDRP HERP HERP1 HERP2 HES1 HES5 HESR1 HEY1 HEY2 HEYL HIF1A HL HRT1 HRT2 HRT3 HRY IGKJRB IGKJRB1 IRA1 KAT2A KAT2B KIAA0200 KIAA0288 KIAA0600 KIAA0744 KIAA0901 KIAA1047 KIAA1261 KIAA1544 KIAA1816 KIAA1819 LYST2 MAML1 MAML2 MAML3 MAMLD1 MITR MOP1 MYC NBEA NCOR1 NCOR2 NOTCH1 OCP2 P300 PASD8 PCAF RBPJ RBPJK RBPSUH RBX1 RNF75 ROC1 RPD3L1 RPS27A SKIIP SKIP SKP1 SKP1A SNW1 TAN1 TBL1 TBL1X TBL1XR1 TBLR1 TCEB1L TLE1 TLE2 TLE4 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Homo sapiens (human)
NOTCH2 Activation and Transmission of Signal to the Nucleus	Contactin-1 Delta-like protein 1 Delta-like protein 4 Disintegrin and metalloproteinase domain-containing protein 10 E3 ubiquitin-protein ligase MIB1 E3 ubiquitin-protein ligase MIB2 E3 ubiquitin-protein ligase NEURL1 E3 ubiquitin-protein ligase NEURL1B Gamma-secretase subunit APH-1A Gamma-secretase subunit APH-1B Gamma-secretase subunit PEN-2 Midkine Neurogenic locus notch homolog protein 2 Nicastrin Polyubiquitin-B Polyubiquitin-C Presenilin-1 Presenilin-2 Protein jagged-1 Protein jagged-2 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A8MQ27 O00548 O14672 O76050 P0CG47 P0CG48 P21741 P49768 P49810 P62979 P62987 P78504 Q04721 Q12860 Q86YT6 Q8WW43 Q92542 Q96AX9 Q96BI3 Q9NR61 Q9NZ42 Q9Y219	AD3 AD4 ADAM10 APH1A APH1B CNTN1 DIP1 DLL1 DLL4 JAG1 JAG2 JAGL1 KIAA0253 KIAA1323 KUZ MADM MDK MIB1 MIB2 MK1 NCSTN NEGF2 NEURL NEURL1 NEURL1A NEURL1B NEURL3 NOTCH2 PEN2 PS1 PS2 PSEN1 PSEN2 PSENEN PSF PSFL PSNL1 PSNL2 RNF67 RPS27A SKD STM2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 ZZANK1 ZZANK2	Homo sapiens (human)
NOTCH2 intracellular domain regulates transcription	Granzyme B Histone acetyltransferase p300 Low affinity immunoglobulin epsilon Fc receptor Mastermind-like domain-containing protein 1 Mastermind-like protein 1 Mastermind-like protein 2 Mastermind-like protein 3 Neurogenic locus notch homolog protein 2 Recombining binding protein suppressor of hairless Transcription factor HES-1 Transcription factor HES-5	P06734 P10144 Q04721 Q06330 Q09472 Q13495 Q14469 Q5TA89 Q8IZL2 Q92585 Q96JK9	BHLHB38 BHLHB39 CD23A CG1 CGL1 CLEC4J CSPB CTLA1 CXorf6 EP300 FCE2 FCER2 GRB GZMB HES1 HES5 HL HRY IGEBF IGKJRB IGKJRB1 KIAA0200 KIAA1816 KIAA1819 MAML1 MAML2 MAML3 MAMLD1 NOTCH2 P300 RBPJ RBPJK RBPSUH	Homo sapiens (human)
NOTCH3 Activation and Transmission of Signal to the Nucleus	Delta-like protein 1 Delta-like protein 4 Disintegrin and metalloproteinase domain-containing protein 10 E3 ubiquitin-protein ligase MIB1 E3 ubiquitin-protein ligase MIB2 E3 ubiquitin-protein ligase NEURL1 E3 ubiquitin-protein ligase NEURL1B Epidermal growth factor receptor Gamma-secretase subunit APH-1A Gamma-secretase subunit APH-1B Gamma-secretase subunit PEN-2 NEDD4-like E3 ubiquitin-protein ligase WWP2 Neurogenic locus notch homolog protein 3 Nicastrin Polyubiquitin-B Polyubiquitin-C Presenilin-1 Presenilin-2 Pro-epidermal growth factor Protein jagged-1 Protein jagged-2 Transforming acidic coiled-coil-containing protein 3 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A8MQ27 O00308 O00548 O14672 O76050 P00533 P01133 P0CG47 P0CG48 P49768 P49810 P62979 P62987 P78504 Q86YT6 Q8WW43 Q92542 Q96AX9 Q96BI3 Q9NR61 Q9NZ42 Q9UM47 Q9Y219 Q9Y6A5	AD3 AD4 ADAM10 APH1A APH1B DIP1 DLL1 DLL4 EGF EGFR ERBB ERBB1 ERIC1 HER1 JAG1 JAG2 JAGL1 KIAA0253 KIAA1323 KUZ MADM MIB1 MIB2 NCSTN NEURL NEURL1 NEURL1A NEURL1B NEURL3 NOTCH3 PEN2 PS1 PS2 PSEN1 PSEN2 PSENEN PSF PSFL PSNL1 PSNL2 RNF67 RPS27A SKD STM2 TACC3 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 WWP2 ZZANK1 ZZANK2	Homo sapiens (human)
NOTCH3 Intracellular Domain Regulates Transcription	CREB-binding protein Disks large-associated protein 5 Fatty acid-binding protein, brain Hairy/enhancer-of-split related with YRPW motif protein 1 Hairy/enhancer-of-split related with YRPW motif protein 2 Hairy/enhancer-of-split related with YRPW motif-like protein Histone acetyltransferase KAT2A Histone acetyltransferase KAT2B Histone acetyltransferase p300 Mastermind-like domain-containing protein 1 Mastermind-like protein 1 Mastermind-like protein 2 Mastermind-like protein 3 Neurogenic locus notch homolog protein 1 Neurogenic locus notch homolog protein 3 Plexin-D1 Pre T-cell antigen receptor alpha Pre-B-cell leukemia transcription factor 1 Protein KIBRA Recombining binding protein suppressor of hairless SNW domain-containing protein 1 Signal transducer and activator of transcription 1-alpha/beta Transcription factor HES-1 Transcription factor HES-5	O15540 P40424 P42224 P46531 Q06330 Q09472 Q13495 Q13573 Q14469 Q15398 Q5TA89 Q6ISU1 Q8IX03 Q8IZL2 Q92585 Q92793 Q92830 Q92831 Q96JK9 Q9NQ87 Q9UBP5 Q9UM47 Q9Y4D7 Q9Y5J3	BHLHB31 BHLHB32 BHLHB33 BHLHB38 BHLHB39 BLBP CBP CG1 CHF1 CHF2 CREBBP CXorf6 DLG7 DLGAP5 EP300 FABP7 FABPB GCN5 GCN5L2 GRL HERP HERP1 HERP2 HES1 HES5 HESR1 HEY1 HEY2 HEYL HL HRT1 HRT2 HRT3 HRY IGKJRB IGKJRB1 KAT2A KAT2B KIAA0008 KIAA0200 KIAA0620 KIAA0869 KIAA1816 KIAA1819 KIBRA MAML1 MAML2 MAML3 MAMLD1 MRG NOTCH1 NOTCH3 P300 PBX1 PCAF PLXND1 PRL PTCRA RBPJ RBPJK RBPSUH SKIIP SKIP SNW1 STAT1 TAN1 WWC1	Homo sapiens (human)
NOTCH4 Activation and Transmission of Signal to the Nucleus	14-3-3 protein zeta/delta Delta-like protein 4 Disintegrin and metalloproteinase domain-containing protein 10 Gamma-secretase subunit APH-1A Gamma-secretase subunit APH-1B Gamma-secretase subunit PEN-2 Neurogenic locus notch homolog protein 4 Nicastrin Presenilin-1 Presenilin-2 Protein jagged-1	O14672 P49768 P49810 P63104 P78504 Q8WW43 Q92542 Q96BI3 Q99466 Q9NR61 Q9NZ42	AD3 AD4 ADAM10 APH1A APH1B DLL4 INT3 JAG1 JAGL1 KIAA0253 KUZ MADM NCSTN NOTCH4 PEN2 PS1 PS2 PSEN1 PSEN2 PSENEN PSF PSFL PSNL1 PSNL2 STM2 YWHAZ	Homo sapiens (human)
NOTCH4 Intracellular Domain Regulates Transcription	Actin, aortic smooth muscle CREB-binding protein Hairy/enhancer-of-split related with YRPW motif protein 1 Hairy/enhancer-of-split related with YRPW motif protein 2 Histone acetyltransferase KAT2A Histone acetyltransferase KAT2B Histone acetyltransferase p300 Mastermind-like domain-containing protein 1 Mastermind-like protein 1 Mastermind-like protein 2 Mastermind-like protein 3 Mothers against decapentaplegic homolog 3 Neurogenic locus notch homolog protein 1 Neurogenic locus notch homolog protein 2 Neurogenic locus notch homolog protein 4 Recombining binding protein suppressor of hairless SNW domain-containing protein 1 Transcription factor HES-1 Transcription factor HES-5 Vascular endothelial growth factor receptor 3	P35916 P46531 P62736 P84022 Q04721 Q06330 Q09472 Q13495 Q13573 Q14469 Q5TA89 Q8IZL2 Q92585 Q92793 Q92830 Q92831 Q96JK9 Q99466 Q9UBP5 Q9Y5J3	ACTA2 ACTSA ACTVS BHLHB31 BHLHB32 BHLHB38 BHLHB39 CBP CG1 CHF1 CHF2 CREBBP CXorf6 EP300 FLT4 GCN5 GCN5L2 GRL HERP HERP1 HERP2 HES1 HES5 HESR1 HEY1 HEY2 HL HRT1 HRT2 HRY IGKJRB IGKJRB1 INT3 KAT2A KAT2B KIAA0200 KIAA1816 KIAA1819 MADH3 MAML1 MAML2 MAML3 MAMLD1 NOTCH1 NOTCH2 NOTCH4 P300 PCAF RBPJ RBPJK RBPSUH SKIIP SKIP SMAD3 SNW1 TAN1 VEGFR3	Homo sapiens (human)
NPAS4 regulates expression of target genes	Aryl hydrocarbon receptor nuclear translocator 2 Aryl hydrocarbon receptor nuclear translocator Basic helix-loop-helix ARNT-like protein 1 Brain-derived neurotrophic factor CREB-binding protein Cyclin-dependent kinase 5 activator 1 Cyclin-dependent kinase 5 E3 ubiquitin-protein ligase Mdm2 Exportin-1 GTP-binding protein GEM IQ motif and SEC7 domain-containing protein 3 Insulin Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Neuronal PAS domain-containing protein 4 Nicotinamide phosphoribosyltransferase Protein c-Fos Proto-oncogene tyrosine-protein kinase receptor Ret RNA binding protein fox-1 homolog 3 Serine/threonine-protein kinase PLK2 Synaptotagmin-10	A6NFN3 O00327 O14980 P01100 P01308 P07949 P23560 P27361 P27540 P28482 P43490 P55040 Q00535 Q00987 Q15078 Q6XYQ8 Q8IUM7 Q92793 Q9HBZ2 Q9NYY3 Q9UPP2	ARNT ARNT2 ARNTL BDNF BHLHE1 BHLHE2 BHLHE5 BHLHE79 BMAL1 CBP CDHF12 CDHR16 CDK5 CDK5R CDK5R1 CDKN5 CREBBP CRM1 ERK1 ERK2 FOS G0S7 GEM INS IQSEC3 KIAA0307 KIAA1110 KIR MAPK1 MAPK3 MDM2 MOP3 NAMPT NCK5A NPAS4 NXF PASD10 PASD3 PBEF PBEF1 PLK2 PRKM1 PRKM2 PRKM3 PSSALRE PTC RBFOX3 RET SNK SYT10 XPO1	Homo sapiens (human)
NR1D1 (REV-ERBA) represses gene expression	Histone deacetylase 3 Nuclear receptor corepressor 1 Nuclear receptor subfamily 1 group D member 1	O15379 O75376 P20393	EAR1 HDAC3 HREV KIAA1047 NCOR1 NR1D1 THRAL	Homo sapiens (human)
NRAGE signals death through JNK	A-kinase anchor protein 13 Active breakpoint cluster region-related protein Bcl-2-like protein 11 Bcl2-associated agonist of cell death Beta-nerve growth factor Ephexin-1 FYVE, RhoGEF and PH domain-containing protein 1 FYVE, RhoGEF and PH domain-containing protein 2 FYVE, RhoGEF and PH domain-containing protein 3 FYVE, RhoGEF and PH domain-containing protein 4 Guanine nucleotide exchange factor DBS Guanine nucleotide exchange factor VAV2 Guanine nucleotide exchange factor VAV3 Guanine nucleotide-binding protein subunit alpha-13 Intersectin-1 Kalirin Melanoma-associated antigen D1 Mitogen-activated protein kinase 8 Neuroepithelial cell-transforming gene 1 protein Obscurin Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein Pleckstrin homology domain-containing family G member 2 Pleckstrin homology domain-containing family G member 5 Protein AATF Protein ECT2 Proto-oncogene DBL Proto-oncogene vav Ras-related C3 botulinum toxin substrate 1 Ras-specific guanine nucleotide-releasing factor 2 Rho guanine nucleotide exchange factor 10-like protein Rho guanine nucleotide exchange factor 10 Rho guanine nucleotide exchange factor 11 Rho guanine nucleotide exchange factor 12 Rho guanine nucleotide exchange factor 15 Rho guanine nucleotide exchange factor 16 Rho guanine nucleotide exchange factor 17 Rho guanine nucleotide exchange factor 18 Rho guanine nucleotide exchange factor 19 Rho guanine nucleotide exchange factor 1 Rho guanine nucleotide exchange factor 26 Rho guanine nucleotide exchange factor 2 Rho guanine nucleotide exchange factor 33 Rho guanine nucleotide exchange factor 35 Rho guanine nucleotide exchange factor 37 Rho guanine nucleotide exchange factor 38 Rho guanine nucleotide exchange factor 39 Rho guanine nucleotide exchange factor 3 Rho guanine nucleotide exchange factor 40 Rho guanine nucleotide exchange factor 4 Rho guanine nucleotide exchange factor 5 Rho guanine nucleotide exchange factor 6 Rho guanine nucleotide exchange factor 7 Rho guanine nucleotide exchange factor 9 Rho guanine nucleotide exchange factor TIAM1 Rho guanine nucleotide exchange factor TIAM2 Son of sevenless homolog 1 Son of sevenless homolog 2 Triple functional domain protein Tumor necrosis factor receptor superfamily member 16	A1IGU5 A5YM69 A8MVX0 O14827 O15013 O15068 O15085 O43307 O43521 O60229 O75962 O94827 O94989 P01138 P08138 P10911 P15498 P45983 P52735 P63000 P98174 Q07889 Q07890 Q12774 Q12802 Q12979 Q13009 Q14155 Q14344 Q15052 Q15811 Q5JSP0 Q5VST9 Q5VV41 Q6ZSZ5 Q7Z628 Q7Z6J4 Q8IVF5 Q8IW93 Q8N4T4 Q8N5V2 Q8TCU6 Q8TER5 Q92888 Q92934 Q92974 Q96DR7 Q96M96 Q96PE2 Q9H7P9 Q9H8V3 Q9HCE6 Q9NR80 Q9NR81 Q9NXL2 Q9NY61 Q9NZN5 Q9UKW4 Q9Y5V3	AATF ABR AKAP13 ARHDH9 ARHGEF1 ARHGEF10 ARHGEF10L ARHGEF11 ARHGEF12 ARHGEF15 ARHGEF16 ARHGEF17 ARHGEF18 ARHGEF19 ARHGEF2 ARHGEF26 ARHGEF3 ARHGEF33 ARHGEF35 ARHGEF37 ARHGEF38 ARHGEF39 ARHGEF4 ARHGEF40 ARHGEF5 ARHGEF5L ARHGEF6 ARHGEF7 ARHGEF8 ARHGEF9 BAD BBC6 BCL2L11 BCL2L8 BIM BRX C9orf100 CHE1 COOL1 COOL2 DBL DED DUET DUO ECT2 EPHEXIN4 FGD1 FGD2 FGD3 FGD4 FGDY FRABP GNA13 GRF2 GRINCHGEF HAPIP HT31 ITSN ITSN1 JNK1 KALRN KIAA0006 KIAA0142 KIAA0294 KIAA0337 KIAA0362 KIAA0380 KIAA0382 KIAA0424 KIAA0521 KIAA0651 KIAA0720 KIAA0915 KIAA1112 KIAA1415 KIAA1556 KIAA1626 KIAA1639 KIAA2016 LARG LBC LFP40 MAGED1 MAPK8 MCF2 MCF2L NBR NET1 NGEF NGF NGFB NGFR NRAGE OBSCN OST P85SPR PAK3BP PIXA PIXB PLEKHG2 PLEKHG5 PREX1 PRKM8 RAC1 RASGRF2 SAPK1 SAPK1C SGEF SH3D1A SOLO SOS1 SOS2 STEF TC25 TEM4 TIAM1 TIAM2 TIM TNFRSF16 TRAD TRIO VAV VAV1 VAV2 VAV3 ZFYVE3 ZFYVE4 ZFYVE5 ZFYVE6	Homo sapiens (human)
NRIF signals cell death from the nucleus	Beta-nerve growth factor Centromere protein R Gamma-secretase subunit APH-1A Gamma-secretase subunit APH-1B Gamma-secretase subunit PEN-2 Mitogen-activated protein kinase 8 Nicastrin Polyubiquitin-B Polyubiquitin-C Presenilin-1 Presenilin-2 Sequestosome-1 TNF receptor-associated factor 6 Tumor necrosis factor receptor superfamily member 16 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	P01138 P08138 P0CG47 P0CG48 P45983 P49768 P49810 P62979 P62987 Q13352 Q13501 Q8WW43 Q92542 Q96BI3 Q9NZ42 Q9Y4K3	AD3 AD4 APH1A APH1B CENPR ITGB3BP JNK1 KIAA0253 MAPK8 NCSTN NGF NGFB NGFR NRIF3 ORCA OSIL PEN2 PRKM8 PS1 PS2 PSEN1 PSEN2 PSENEN PSF PSFL PSNL1 PSNL2 RNF85 RPS27A SAPK1 SAPK1C SQSTM1 STM2 TNFRSF16 TRAF6 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Homo sapiens (human)
NS1 Mediated Effects on Host Pathways	Aladin E3 SUMO-protein ligase RanBP2 Importin subunit alpha-1 Importin subunit alpha-3 Importin subunit alpha-4 Importin subunit alpha-5 Importin subunit alpha-6 Importin subunit alpha-8 Importin subunit beta-1 Non-structural protein 1 Nuclear envelope pore membrane protein POM 121 Nuclear envelope pore membrane protein POM 121C Nuclear pore complex protein Nup107 Nuclear pore complex protein Nup133 Nuclear pore complex protein Nup153 Nuclear pore complex protein Nup155 Nuclear pore complex protein Nup160 Nuclear pore complex protein Nup205 Nuclear pore complex protein Nup214 Nuclear pore complex protein Nup50 Nuclear pore complex protein Nup85 Nuclear pore complex protein Nup88 Nuclear pore complex protein Nup93 Nuclear pore glycoprotein p62 Nuclear pore membrane glycoprotein 210 Nucleoporin NDC1 Nucleoporin NUP188 Nucleoporin NUP35 Nucleoporin NUP42 Nucleoporin Nup37 Nucleoporin Nup43 Nucleoporin p54 Nucleoprotein TPR Protein SEC13 homolog Ubiquitin-like protein ISG15 mRNA export factor RAE1	A8CG34 A9QM74 O00505 O00629 O15131 O15504 O75694 P03496 P05161 P12270 P35658 P37198 P49790 P49792 P52292 P52294 P55735 P57740 P78406 Q12769 Q14974 Q5SRE5 Q7Z3B4 Q8N1F7 Q8NFH3 Q8NFH4 Q8NFH5 Q8TEM1 Q8WUM0 Q92621 Q96HA1 Q99567 Q9BTX1 Q9BW27 Q9NRG9 Q9UKX7	AAAS ADRACALA C7orf14 CAIN CAN CG1 D3S1231E G1P2 ISG15 KIAA0023 KIAA0095 KIAA0169 KIAA0197 KIAA0225 KIAA0618 KIAA0791 KIAA0906 KPNA1 KPNA2 KPNA3 KPNA4 KPNA5 KPNA7 KPNB1 MP44 MRNP41 NDC1 NPAP60L NS NTF97 NUP107 NUP120 NUP121 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP358 NUP37 NUP42 NUP43 NUP50 NUP53 NUP54 NUP62 NUP75 NUP85 NUP88 NUP93 NUPL2 PCNT1 POM121 POM121A POM121C QIP1 QIP2 RAE1 RANBP2 RCH1 RCH2 SEC13 SEC13A SEC13L1 SEC13R SRP1 TMEM48 TPR UCRP	Homo sapiens (human)
NTF3 activates NTRK2 (TRKB) signaling	BDNF/NT-3 growth factors receptor Neurotrophin-3	P20783 Q16620	NTF3 NTRK2 TRKB	Homo sapiens (human)
NTF3 activates NTRK3 signaling	NT-3 growth factor receptor Neurotrophin-3	P20783 Q16288	NTF3 NTRK3 TRKC	Homo sapiens (human)
NTF4 activates NTRK2 (TRKB) signaling	BDNF/NT-3 growth factors receptor Neurotrophin-4	P34130 Q16620	NTF4 NTF5 NTRK2 TRKB	Homo sapiens (human)
NTRK2 activates RAC1	BDNF/NT-3 growth factors receptor Brain-derived neurotrophic factor Dedicator of cytokinesis protein 3 Ras-related C3 botulinum toxin substrate 1	P23560 P63000 Q16620 Q8IZD9	BDNF DOCK3 KIAA0299 MOCA NTRK2 RAC1 TC25 TRKB	Homo sapiens (human)
NTRK3 as a dependence receptor	Apoptosis regulator BAX NT-3 growth factor receptor Negative elongation factor B	Q07812 Q16288 Q8WX92	BAX BCL2L4 COBRA1 KIAA1182 NELFB NTRK3 TRKC	Homo sapiens (human)
NVP-TAE684-resistant ALK mutants	ALK tyrosine kinase receptor	Q9UM73	ALK	Homo sapiens (human)
Na+/Cl- dependent neurotransmitter transporters	Chromaffin granule amine transporter Inactive sodium-dependent neutral amino acid transporter B(0)AT3 Sodium- and chloride-dependent GABA transporter 1 Sodium- and chloride-dependent GABA transporter 2 Sodium- and chloride-dependent GABA transporter 3 Sodium- and chloride-dependent betaine transporter Sodium- and chloride-dependent glycine transporter 1 Sodium- and chloride-dependent glycine transporter 2 Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+) Sodium- and chloride-dependent taurine transporter Sodium- and chloride-dependent transporter XTRP3 Sodium-dependent dopamine transporter Sodium-dependent neutral amino acid transporter B(0)AT1 Sodium-dependent neutral amino acid transporter B(0)AT2 Sodium-dependent noradrenaline transporter Sodium-dependent proline transporter Solute carrier family 22 member 1 Solute carrier family 22 member 2 Synaptic vesicular amine transporter	O15244 O15245 P23975 P30531 P31641 P48065 P48066 P48067 P54219 Q01959 Q05940 Q695T7 Q96N87 Q99884 Q9H2J7 Q9NP91 Q9NSD5 Q9UN76 Q9Y345	B0AT1 B0AT2 B0AT3 BGT1 DAT1 GABATR GABT1 GABT3 GAT1 GAT2 GAT3 GLYT2 NAT1 NET1 NTT73 OCT1 OCT2 PROT SBAT1 SIT1 SLC18A1 SLC18A2 SLC22A1 SLC22A2 SLC6A1 SLC6A11 SLC6A12 SLC6A13 SLC6A14 SLC6A15 SLC6A18 SLC6A19 SLC6A2 SLC6A20 SLC6A3 SLC6A5 SLC6A6 SLC6A7 SLC6A9 SVMT VAT1 VMAT1 VMAT2 XT3 XTRP2 XTRP3	Homo sapiens (human)
Nectin/Necl trans heterodimerization	Cell adhesion molecule 1 Cell adhesion molecule 3 Nectin-1 Nectin-2 Nectin-3 Nectin-4 Poliovirus receptor	P15151 Q15223 Q8N126 Q92692 Q96NY8 Q9BY67 Q9NQS3	CADM1 CADM3 HVEB HVEC IGSF4 IGSF4A IGSF4B LNIR NECL1 NECL2 NECTIN1 NECTIN2 NECTIN3 NECTIN4 PRR1 PRR2 PRR3 PRR4 PVR PVRL1 PVRL2 PVRL3 PVRL4 PVS SYNCAM SYNCAM3 TSLC1 TSLL1	Homo sapiens (human)
Neddylation	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 APC membrane recruitment protein 1 Ankyrin repeat and SOCS box protein 10 Ankyrin repeat and SOCS box protein 11 Ankyrin repeat and SOCS box protein 12 Ankyrin repeat and SOCS box protein 13 Ankyrin repeat and SOCS box protein 14 Ankyrin repeat and SOCS box protein 15 Ankyrin repeat and SOCS box protein 16 Ankyrin repeat and SOCS box protein 17 Ankyrin repeat and SOCS box protein 18 Ankyrin repeat and SOCS box protein 1 Ankyrin repeat and SOCS box protein 2 Ankyrin repeat and SOCS box protein 3 Ankyrin repeat and SOCS box protein 4 Ankyrin repeat and SOCS box protein 5 Ankyrin repeat and SOCS box protein 6 Ankyrin repeat and SOCS box protein 7 Ankyrin repeat and SOCS box protein 8 Ankyrin repeat and SOCS box protein 9 Ankyrin repeat domain-containing protein 9 BTB/POZ domain-containing protein 1 BTB/POZ domain-containing protein 6 BTB/POZ domain-containing protein KCTD6 BTB/POZ domain-containing protein KCTD7 Baculoviral IAP repeat-containing protein 5 Breast cancer type 1 susceptibility protein COMM domain-containing protein 10 COMM domain-containing protein 1 COMM domain-containing protein 2 COMM domain-containing protein 3 COMM domain-containing protein 4 COMM domain-containing protein 5 COMM domain-containing protein 6 COMM domain-containing protein 7 COMM domain-containing protein 8 COMM domain-containing protein 9 COP9 signalosome complex subunit 1 COP9 signalosome complex subunit 2 COP9 signalosome complex subunit 3 COP9 signalosome complex subunit 4 COP9 signalosome complex subunit 5 COP9 signalosome complex subunit 6 COP9 signalosome complex subunit 7a COP9 signalosome complex subunit 7b COP9 signalosome complex subunit 8 Coiled-coil domain-containing protein 22 Coiled-coil domain-containing protein 8 Cullin-1 Cullin-2 Cullin-3 Cullin-4A Cullin-4B Cullin-5 Cullin-7 Cullin-9 Cullin-associated NEDD8-dissociated protein 1 Cyclin-F Cyclin-dependent kinase inhibitor 1 Cytokine-inducible SH2-containing protein DCN1-like protein 1 DCN1-like protein 2 DCN1-like protein 3 DCN1-like protein 4 DCN1-like protein 5 DDB1- and CUL4-associated factor 10 DDB1- and CUL4-associated factor 11 DDB1- and CUL4-associated factor 13 DDB1- and CUL4-associated factor 16 DDB1- and CUL4-associated factor 17 DDB1- and CUL4-associated factor 4 DDB1- and CUL4-associated factor 5 DDB1- and CUL4-associated factor 6 DDB1- and CUL4-associated factor 7 DDB1- and CUL4-associated factor 8 DET1- and DDB1-associated protein 1 DNA damage-binding protein 1 DNA damage-binding protein 2 DNA excision repair protein ERCC-8 Denticleless protein homolog Dipeptidyl peptidase 3 E3 ubiquitin-protein ligase COP1 E3 ubiquitin-protein ligase RBX1 Elongin-B Elongin-C Endothelial PAS domain-containing protein 1 F-box and leucine-rich protein 22 F-box and leucine-rich repeat protein 13 F-box only protein 10 F-box only protein 11 F-box only protein 15 F-box only protein 17 F-box only protein 21 F-box only protein 22 F-box only protein 27 F-box only protein 2 F-box only protein 30 F-box only protein 31 F-box only protein 32 F-box only protein 40 F-box only protein 41 F-box only protein 44 F-box only protein 4 F-box only protein 6 F-box only protein 7 F-box only protein 9 F-box/LRR-repeat protein 12 F-box/LRR-repeat protein 14 F-box/LRR-repeat protein 15 F-box/LRR-repeat protein 16 F-box/LRR-repeat protein 18 F-box/LRR-repeat protein 19 F-box/LRR-repeat protein 20 F-box/LRR-repeat protein 3 F-box/LRR-repeat protein 4 F-box/LRR-repeat protein 5 F-box/LRR-repeat protein 7 F-box/LRR-repeat protein 8 F-box/WD repeat-containing protein 10 F-box/WD repeat-containing protein 11 F-box/WD repeat-containing protein 12 F-box/WD repeat-containing protein 1A F-box/WD repeat-containing protein 2 F-box/WD repeat-containing protein 4 F-box/WD repeat-containing protein 5 F-box/WD repeat-containing protein 7 F-box/WD repeat-containing protein 8 F-box/WD repeat-containing protein 9 Gigaxonin Histone-binding protein RBBP7 Hypoxia-inducible factor 1-alpha Hypoxia-inducible factor 3-alpha Kelch repeat and BTB domain-containing protein 13 Kelch repeat and BTB domain-containing protein 6 Kelch repeat and BTB domain-containing protein 7 Kelch repeat and BTB domain-containing protein 8 Kelch-like ECH-associated protein 1 Kelch-like protein 11 Kelch-like protein 13 Kelch-like protein 20 Kelch-like protein 21 Kelch-like protein 22 Kelch-like protein 25 Kelch-like protein 2 Kelch-like protein 3 Kelch-like protein 41 Kelch-like protein 42 Kelch-like protein 5 Kelch-like protein 9 LIM domain only protein 7 Leucine-rich repeat protein 1 Leucine-rich repeat-containing protein 41 Mitochondrial ubiquitin ligase activator of NFKB 1 NEDD8-activating enzyme E1 catalytic subunit NEDD8-activating enzyme E1 regulatory subunit NEDD8-conjugating enzyme UBE2F NEDD8-conjugating enzyme Ubc12 NEDD8 Neuralized-like protein 2 Nuclear factor erythroid 2-related factor 2 Nuclear protein localization protein 4 homolog Obscurin-like protein 1 Partner and localizer of BRCA2 Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Protein X Protein fem-1 homolog A Protein fem-1 homolog B Protein fem-1 homolog C Pumilio homolog 2 Putative F-box/LRR-repeat protein 21 RING-box protein 2 Retinoblastoma-binding protein 5 S-phase kinase-associated protein 1 S-phase kinase-associated protein 2 SPRY domain-containing SOCS box protein 1 SPRY domain-containing SOCS box protein 2 SPRY domain-containing SOCS box protein 3 SPRY domain-containing SOCS box protein 4 Sentrin-specific protease 8 Sequestosome-1 Suppressor of cytokine signaling 2 Suppressor of cytokine signaling 3 Suppressor of cytokine signaling 5 Suppressor of cytokine signaling 6 Transitional endoplasmic reticulum ATPase Tubby-related protein 4 UBX domain-containing protein 7 Ubiquitin D Ubiquitin carboxyl-terminal hydrolase isozyme L3 Ubiquitin recognition factor in ER-associated degradation protein 1 Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 D2 Ubiquitin-conjugating enzyme E2 D3 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein WD and tetratricopeptide repeats protein 1 WD repeat and SOCS box-containing protein 1 WD repeat and SOCS box-containing protein 2 WD repeat-containing protein 5 Zinc finger and BTB domain-containing protein 16 von Hippel-Lindau disease tumor suppressor	A5LHX3 A6NK59 C9JR72 O00231 O00232 O00233 O00487 O14508 O14543 O14544 O14818 O15205 O15392 O43242 O60662 O60826 O75147 O75159 O75832 O94888 O94952 O95198 P0CG47 P0CG48 P15374 P17980 P20618 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P35998 P38398 P38936 P40306 P40337 P41002 P43686 P48556 P49720 P49721 P51665 P51668 P55036 P55072 P57775 P60896 P60900 P61077 P61081 P61201 P61289 P61962 P61964 P62191 P62195 P62333 P62837 P62877 P62979 P62987 P63208 Q05516 Q06323 Q13098 Q13200 Q13216 Q13309 Q13501 Q13564 Q13616 Q13617 Q13618 Q13619 Q13620 Q14145 Q14997 Q14999 Q15008 Q15291 Q15345 Q15369 Q15370 Q15843 Q16236 Q16401 Q16531 Q16576 Q16665 Q2F514 Q53GT1 Q58WW2 Q5H9S7 Q5JTC6 Q5QP82 Q5TAQ9 Q5XUX0 Q5XUX1 Q5XX13 Q6P050 Q6PCT2 Q6PH85 Q6PJ21 Q6X9E4 Q6ZVZ8 Q7L5N1 Q7Z4G1 Q86V97 Q86VP6 Q86VX2 Q86X83 Q86XK2 Q86YC2 Q8IWE4 Q8IWT3 Q8N1E6 Q8N3Y1 Q8N461 Q8N5D0 Q8N668 Q8NC69 Q8NCQ5 Q8NEE6 Q8NEZ5 Q8NFY9 Q8NHY2 Q8NI29 Q8TAA3 Q8TAT6 Q8TB52 Q8TB72 Q8TBC4 Q8TEB1 Q8TF61 Q8WV16 Q8WVZ9 Q8WWI1 Q8WWX0 Q8WXH4 Q8WXI3 Q8WXJ9 Q8WXK1 Q8WXK3 Q8WXK4 Q92466 Q92530 Q92564 Q92890 Q92905 Q93034 Q969H0 Q969M7 Q969P5 Q969U6 Q969V5 Q96A44 Q96BD6 Q96BM1 Q96CD0 Q96DX5 Q96EF6 Q96GG9 Q96IG2 Q96JK2 Q96JP0 Q96KE9 Q96L50 Q96LD8 Q96ME1 Q96MP8 Q96NS5 Q96PQ7 Q96Q27 Q99436 Q99460 Q99619 Q99627 Q99814 Q9BR09 Q9BSK4 Q9BT78 Q9BTE7 Q9BW61 Q9GZQ3 Q9H0A8 Q9H0C5 Q9H0H3 Q9H0W5 Q9H2C0 Q9H469 Q9H4M3 Q9H672 Q9H765 Q9H9Q2 Q9NRD1 Q9NRJ4 Q9NSE2 Q9NV06 Q9NVR0 Q9NWX5 Q9NX08 Q9NXF7 Q9NXK8 Q9NY33 Q9NYS7 Q9NZJ0 Q9P000 Q9P2J3 Q9P2K6 Q9P2N7 Q9UBF6 Q9UBI1 Q9UBW8 Q9UH77 Q9UH90 Q9UJP4 Q9UJT9 Q9UK22 Q9UK73 Q9UK96 Q9UK97 Q9UKA1 Q9UKA2 Q9UKB1 Q9UKT5 Q9UKT6 Q9UKT7 Q9UKT8 Q9UL46 Q9UNM6 Q9UNS2 Q9Y297 Q9Y2M5 Q9Y2N7 Q9Y3I1 Q9Y574 Q9Y575 Q9Y576 Q9Y6G5 Q9Y6I7	AMER1 ANKRD9 API4 APPBP1 ASB1 ASB10 ASB11 ASB12 ASB13 ASB14 ASB15 ASB16 ASB17 ASB18 ASB2 ASB3 ASB4 ASB5 ASB6 ASB7 ASB8 ASB9 BCRG2 BDPL BHLHE17 BHLHE73 BHLHE78 BIG3 BIRC5 BKLHD2 BRCA1 BTBD1 BTBD6 BTRC BTRCP BTRCP2 BUP C10orf8 C13orf17 C15orf1 C16orf22 C16orf31 C19orf58 C1orf166 C20orf163 C20orf92 C2orf37 C2orf5 C4orf30 C7orf76 CAND1 CAP20 CCDC22 CCDC8 CCNF CDKN1 CDKN1A CDT2 CDW1 CIP1 CIS2 CIS3 CIS4 CIS6 CISH CISH5 CISH6 CKN1 COMMD1 COMMD10 COMMD2 COMMD3 COMMD4 COMMD5 COMMD6 COMMD7 COMMD8 COMMD9 COP1 COPS1 COPS2 COPS3 COPS4 COPS5 COPS6 COPS7A COPS7B COPS8 CSA CSN1 CSN2 CSN3 CSN4 CSN5 CSN6 CSN7A CSN7B CSN8 CUL1 CUL2 CUL3 CUL4A CUL4B CUL5 CUL7 CUL9 CXorf37 DCAF10 DCAF11 DCAF13 DCAF16 DCAF17 DCAF2 DCAF4 DCAF5 DCAF6 DCAF7 DCAF8 DCN1 DCUN1D1 DCUN1D2 DCUN1D3 DCUN1D4 DCUN1D5 DCUN1L1 DCUN1L2 DDA1 DDB1 DDB2 DEN1 DERP10 DPP3 DRC6 DSS1 DTL ELOB ELOC EMC19 ENC2 EPAS1 EPRAP ERCC8 F1AA FAM123B FANCN FAT10 FBG2 FBG3 FBG4 FBG5 FBL12 FBL13 FBL14 FBL16 FBL18 FBL19 FBL2 FBL21 FBL3 FBL3A FBL4 FBL5 FBL6 FBL7 FBL8 FBS2 FBW12 FBW1A FBW1B FBW2 FBW4 FBW5 FBW6 FBW7 FBW8 FBW9 FBX1 FBX10 FBX11 FBX14 FBX15 FBX17 FBX2 FBX20 FBX21 FBX22 FBX26 FBX27 FBX29 FBX30 FBX31 FBX4 FBX40 FBX41 FBX44 FBX6 FBX6A FBX7 FBX9 FBXL1 FBXL12 FBXL13 FBXL14 FBXL15 FBXL16 FBXL18 FBXL19 FBXL20 FBXL21 FBXL21P FBXL22 FBXL3 FBXL3A FBXL3B FBXL3P FBXL4 FBXL5 FBXL7 FBXL8 FBXO1 FBXO10 FBXO11 FBXO12 FBXO15 FBXO17 FBXO2 FBXO20 FBXO21 FBXO22 FBXO26 FBXO27 FBXO29 FBXO30 FBXO31 FBXO32 FBXO35 FBXO37 FBXO4 FBXO40 FBXO41 FBXO44 FBXO6 FBXO6A FBXO7 FBXO9 FBXW10 FBXW11 FBXW12 FBXW1A FBXW1B FBXW2 FBXW4 FBXW5 FBXW6 FBXW7 FBXW8 FBXW9 FEM1A FEM1B FEM1C FLR1 FWD2 G18 GAN GAN1 GIDE GPS1 GRCC9 H326 H7AP1 HAN11 HC2 HC3 HC8 HC9 HEL-220 HEL-S-70 HIF1A HIF2A HIF3A HSPC HVIP IAP4 IFI5111 INRF2 IQWD1 JAB1 KBTBD10 KBTBD13 KBTBD6 KBTBD7 KBTBD8 KCTD6 KCTD7 KEAP1 KIAA0072 KIAA0076 KIAA0077 KIAA0107 KIAA0132 KIAA0235 KIAA0276 KIAA0396 KIAA0469 KIAA0617 KIAA0657 KIAA0671 KIAA0695 KIAA0696 KIAA0708 KIAA0794 KIAA0829 KIAA0840 KIAA0858 KIAA0875 KIAA1037 KIAA1129 KIAA1146 KIAA1195 KIAA1309 KIAA1340 KIAA1354 KIAA1397 KIAA1499 KIAA1785 KIAA1824 KIAA1842 KIAA1940 KLEIP KLHDC5 KLHL11 KLHL13 KLHL16 KLHL19 KLHL2 KLHL20 KLHL21 KLHL22 KLHL25 KLHL3 KLHL41 KLHL42 KLHL5 KLHL9 KLHLX KRP1 L2DTL LMO7 LMP10 LMP2 LMP7 LMPX LMPY LRR1 LRRC41 MAPL MB1 MCB1 MDA6 MECL1 MIP224 MOP1 MOP2 MOP7 MOV34L MSS1 MUF1 MUL1 MULAN MURR1 NAE1 NCE2 NEDD8 NEDP1 NEURL2 NFE2L2 NPL4 NPLOC4 NRF2 NS5ATP8 NU OBSL1 OCP2 ORCA OSIL PALB2 PARC PASD2 PASD7 PASD8 PCIA1 PFAAP4 PIC1 PLZF POH1 PPIL5 PRMT11 PRMT9 PROS26 PROS27 PROS30 PRSC2 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 PUBC1 PUM2 PUMH2 RAMP RBAP46 RBBP5 RBBP7 RBQ3 RBX1 RBX2 RFWD2 RING10 RING12 RNF200 RNF218 RNF53 RNF7 RNF75 ROC1 ROC2 RP42 RPS27A SAG SCCRO SCCRO3 SCCRO5 SDI1 SEL10 SEM1 SENP8 SFT SHFDG1 SHFM1 SHFM3 SKP1 SKP1A SKP2 SOCS2 SOCS3 SOCS4 SOCS5 SOCS6 SPSB1 SPSB2 SPSB3 SPSB4 SQSTM1 SSB1 SSB2 SSB3 SSB4 SSI2 SSI3 STATI2 SUG1 SUG2 SWIP1 TAKRP TBP1 TBP7 TCEB1 TCEB1L TCEB2 TIP120 TIP120A TRAP2 TRIP15 TUBL4 TULP4 TUSP UBA3 UBA52 UBA80 UBB UBC UBC12 UBC4 UBC5A UBC5B UBC5C UBCEP1 UBCEP2 UBCH4 UBCH5 UBCH5A UBCH5B UBCH5C UBD UBE1C UBE2D1 UBE2D2 UBE2D3 UBE2F UBE2M UBXD7 UBXN7 UCHL3 UFD1 UFD1L VACM1 VCIA1 VCP VHL VIT1 WAF1 WDR21 WDR21A WDR22 WDR23 WDR32 WDR42A WDR5 WDR68 WDSOF1 WDTC1 WSB1 WSB2 WTX X XAP1 Y Y2 Z ZBTB16 ZNF145 x	Homo sapiens (human)
Nef Mediated CD4 Down-regulation	ADP-ribosylation factor 1 AP-2 complex subunit alpha-1 AP-2 complex subunit alpha-2 AP-2 complex subunit beta AP-2 complex subunit mu AP-2 complex subunit sigma Protein Nef T-cell surface glycoprotein CD4 Tyrosine-protein kinase Lck V-type proton ATPase subunit H	O94973 O95782 P01730 P04601 P06239 P53680 P63010 P84077 Q96CW1 Q9UI12	ADTAA ADTAB ADTB2 AP17 AP2A1 AP2A2 AP2B1 AP2M1 AP2S1 ARF1 ATP6V1H CD4 CLAPA1 CLAPA2 CLAPB1 CLAPM1 CLAPS2 HIP9 HYPJ KIAA0109 KIAA0899 LCK nef	Homo sapiens (human)
Nef Mediated CD8 Down-regulation	AP-2 complex subunit alpha-1 AP-2 complex subunit alpha-2 AP-2 complex subunit beta AP-2 complex subunit mu AP-2 complex subunit sigma Protein Nef T-cell surface glycoprotein CD8 beta chain V-type proton ATPase subunit H	O94973 O95782 P04601 P10966 P53680 P63010 Q96CW1 Q9UI12	ADTAA ADTAB ADTB2 AP17 AP2A1 AP2A2 AP2B1 AP2M1 AP2S1 ATP6V1H CD8B CD8B1 CLAPA1 CLAPA2 CLAPB1 CLAPM1 CLAPS2 HIP9 HYPJ KIAA0109 KIAA0899 nef	Homo sapiens (human)
Nef and signal transduction	Dedicator of cytokinesis protein 2 Engulfment and cell motility protein 1 Protein Nef Ras-related C3 botulinum toxin substrate 1 Serine/threonine-protein kinase PAK 2 Tyrosine-protein kinase Fyn Tyrosine-protein kinase HCK Tyrosine-protein kinase Lck	P04601 P06239 P06241 P08631 P63000 Q13177 Q92556 Q92608	DOCK2 ELMO1 FYN HCK KIAA0209 KIAA0281 LCK PAK2 RAC1 TC25 nef	Homo sapiens (human)
Nef mediated downregulation of CD28 cell surface expression	AP-2 complex subunit mu Protein Nef T-cell-specific surface glycoprotein CD28	P04601 P10747 Q96CW1	AP2M1 CD28 CLAPM1 KIAA0109 nef	Homo sapiens (human)

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