GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **1401 - 1425** of **2090** in total

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Pathway Name ▼	Protein Name	UniProt ID	Gene Symbol	Organism	GlyTouCan ID
Formation of TC-NER Pre-Incision Complex	CDK-activating kinase assembly factor MAT1 COP9 signalosome complex subunit 1 COP9 signalosome complex subunit 2 COP9 signalosome complex subunit 3 COP9 signalosome complex subunit 4 COP9 signalosome complex subunit 5 COP9 signalosome complex subunit 6 COP9 signalosome complex subunit 7a COP9 signalosome complex subunit 7b COP9 signalosome complex subunit 8 Cullin-4A Cullin-4B Cyclin-H Cyclin-dependent kinase 7 DNA damage-binding protein 1 DNA excision repair protein ERCC-6 DNA excision repair protein ERCC-8 DNA repair protein complementing XP-A cells DNA-directed RNA polymerase II subunit RPB11-a DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 E3 ubiquitin-protein ligase RBX1 General transcription and DNA repair factor IIH helicase subunit XPD General transcription and DNA repair factor IIH helicase/translocase subunit XPB General transcription factor IIH subunit 1 General transcription factor IIH subunit 2 General transcription factor IIH subunit 3 General transcription factor IIH subunit 4 General transcription factor IIH subunit 5 Peptidyl-prolyl cis-trans isomerase E Polyubiquitin-B Polyubiquitin-C Pre-mRNA-processing factor 19 Pre-mRNA-splicing factor ISY1 homolog Pre-mRNA-splicing factor SYF1 RNA helicase aquarius Transcription elongation factor A protein 1 UV-stimulated scaffold protein A Ubiquitin carboxyl-terminal hydrolase 7 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Zinc finger protein 830	O15514 O60306 P0CG47 P0CG48 P18074 P19387 P19388 P19447 P23025 P23193 P24928 P30876 P32780 P36954 P50613 P51946 P51948 P52434 P52435 P53803 P61201 P61218 P62487 P62875 P62877 P62979 P62987 Q03468 Q13098 Q13216 Q13619 Q13620 Q13888 Q13889 Q16531 Q2YD98 Q6ZYL4 Q7L5N1 Q92759 Q92905 Q93009 Q96NB3 Q99627 Q9BT78 Q9H9Q2 Q9HCS7 Q9UBW8 Q9ULR0 Q9UMS4 Q9UNP9 Q9UNS2	AQR BTF2 BTF2P44 C6orf175 CAK CAK1 CAP35 CCDC16 CCNH CDK7 CDKN7 CKN1 COPS1 COPS2 COPS3 COPS4 COPS5 COPS6 COPS7A COPS7B COPS8 CSA CSB CSN1 CSN2 CSN3 CSN4 CSN5 CSN6 CSN7A CSN7B CSN8 CUL4A CUL4B CYP33 DDB1 DERP10 ERCC2 ERCC3 ERCC6 ERCC8 GPS1 GTF2H1 GTF2H2 GTF2H3 GTF2H4 GTF2H5 GTF2S HAUSP HCNP HVIP ISY1 JAB1 KIAA0560 KIAA0695 KIAA1160 KIAA1177 KIAA1530 MAT1 MNAT1 MO15 NMP200 POLR2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J1 POLR2K POLR2L POLRF PPIE PRP19 PRPF19 RBX1 RNF66 RNF75 ROC1 RPB7 RPS27A SNEV STK1 SYF1 TCEA1 TFIIS TRIP15 TTDA UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 USP7 UVSSA XAB2 XAP1 XPA XPAC XPB XPBC XPD XPDC ZNF830	Homo sapiens (human)
Formation of Senescence-Associated Heterochromatin Foci (SAHF)	Calcineurin-binding protein cabin-1 Cellular tumor antigen p53 E1A-binding protein p400 High mobility group protein HMG-I/HMG-Y High mobility group protein HMGI-C Histone H1.0 Histone H1.1 Histone H1.2 Histone H1.3 Histone H1.4 Histone H1.5 Histone chaperone ASF1A Lamin-B1 Protein HIRA Retinoblastoma-associated protein Ubinuclein-1	P04637 P06400 P07305 P10412 P16401 P16402 P16403 P17096 P20700 P52926 P54198 Q02539 Q96L91 Q9NPG3 Q9Y294 Q9Y6J0	ASF1A CABIN1 CAGH32 DGCR1 EP400 H1-0 H1-1 H1-2 H1-3 H1-4 H1-5 H1F0 H1F1 H1F2 H1F3 H1F4 H1F5 H1FV HIR HIRA HIST1H1A HIST1H1B HIST1H1C HIST1H1D HIST1H1E HMGA1 HMGA2 HMGIC HMGIY KIAA0330 KIAA1498 KIAA1818 LMN2 LMNB LMNB1 P53 RB1 TNRC12 TP53 TUPLE1 UBN1	Homo sapiens (human)
Formation of RNA Pol II elongation complex	AF4/FMR2 family member 4 CDK-activating kinase assembly factor MAT1 Cyclin-H Cyclin-K Cyclin-T1 Cyclin-T2 Cyclin-dependent kinase 7 Cyclin-dependent kinase 9 DNA-directed RNA polymerase II subunit RPB11-a DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 ELL-associated factor 1 ELL-associated factor 2 Elongin-A2 Elongin-A Elongin-B Elongin-C FACT complex subunit SPT16 FACT complex subunit SSRP1 General transcription and DNA repair factor IIH helicase subunit XPD General transcription and DNA repair factor IIH helicase/translocase subunit XPB General transcription factor IIF subunit 1 General transcription factor IIF subunit 2 General transcription factor IIH subunit 1 General transcription factor IIH subunit 2 General transcription factor IIH subunit 3 General transcription factor IIH subunit 4 General transcription factor IIH subunit 5 Negative elongation factor A Negative elongation factor B Negative elongation factor C/D Negative elongation factor E Nuclear cap-binding protein subunit 1 Nuclear cap-binding protein subunit 2 Parafibromin Protein AF-9 Protein ENL Protein IWS1 homolog RNA polymerase II elongation factor ELL RNA polymerase II subunit A C-terminal domain phosphatase RNA polymerase II-associated factor 1 homolog RNA polymerase-associated protein CTR9 homolog RNA polymerase-associated protein LEO1 RNA polymerase-associated protein RTF1 homolog Superkiller complex protein 8 Transcription elongation factor A protein 1 Transcription elongation factor SPT4 Transcription elongation factor SPT5 Transcription elongation factor SPT6	O00267 O15514 O60563 O60583 O75909 P13984 P18074 P18615 P19387 P19388 P19447 P23193 P24928 P30876 P32780 P35269 P36954 P42568 P50613 P50750 P51946 P51948 P52298 P52434 P52435 P53803 P55199 P61218 P62487 P62875 P63272 Q03111 Q08945 Q09161 Q13888 Q13889 Q14241 Q15369 Q15370 Q6P1J9 Q6PD62 Q6ZYL4 Q7KZ85 Q8IXH7 Q8IYF1 Q8N7H5 Q8WVC0 Q8WX92 Q92541 Q92759 Q96CJ1 Q96JC9 Q96ST2 Q9GZS3 Q9H3P2 Q9UHB7 Q9Y5B0 Q9Y5B9	AF5Q31 AF9 AFF4 BTF2 BTF2P44 C19orf17 C1orf28 C6orf175 CAK CAK1 CAP35 CBP20 CBP80 CCNH CCNK CCNT1 CCNT2 CDC2L4 CDC73 CDK7 CDK9 CDKN7 COBRA1 CPR4 CTDP1 CTR9 EAF1 EAF2 ELL ELOA ELOA2 ELOB ELOC ENL ERCC2 ERCC3 FACT140 FACT80 FACTP140 FCP1 GTF2F1 GTF2F2 GTF2H1 GTF2H2 GTF2H3 GTF2H4 GTF2H5 GTF2S HRPT2 IWS1 IWS1L KIAA0155 KIAA0162 KIAA0252 KIAA1182 LEO1 LTG19 MAT1 MCEF MLLT1 MLLT3 MNAT1 MO15 NCBP NCBP1 NCBP2 NELFA NELFB NELFCD NELFD NELFE PAF1 PD2 POLR2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J1 POLR2K POLR2L POLRF RAP30 RAP74 RD RDBP RDL RNF66 RPB7 RTF1 SH2BP1 SKIC8 SPT4H SPT5 SPT5H SPT6H SSRP1 STK1 SUPT16H SUPT4H SUPT4H1 SUPT5H SUPT6H TAK TCEA1 TCEB1 TCEB2 TCEB3 TCEB3B TCEB3L TFIIS TH1 TH1L TRAITS TTDA WDR61 WHSC2 XPB XPBC XPD XPDC YEATS1 YEATS3	Homo sapiens (human)
Formation of Incision Complex in GG-NER	CDK-activating kinase assembly factor MAT1 Centrin-2 Chromodomain-helicase-DNA-binding protein 1-like Cullin-4A Cullin-4B Cyclin-H Cyclin-dependent kinase 7 DNA damage-binding protein 1 DNA damage-binding protein 2 DNA excision repair protein ERCC-1 DNA excision repair protein ERCC-5 DNA repair endonuclease XPF DNA repair protein complementing XP-A cells DNA repair protein complementing XP-C cells E3 SUMO-protein ligase PIAS1 E3 SUMO-protein ligase PIAS3 E3 ubiquitin-protein ligase Arkadia E3 ubiquitin-protein ligase RBX1 General transcription and DNA repair factor IIH helicase subunit XPD General transcription and DNA repair factor IIH helicase/translocase subunit XPB General transcription factor IIH subunit 1 General transcription factor IIH subunit 2 General transcription factor IIH subunit 3 General transcription factor IIH subunit 4 General transcription factor IIH subunit 5 Poly [ADP-ribose] polymerase 1 Poly [ADP-ribose] polymerase 2 Polyubiquitin-B Polyubiquitin-C Replication protein A 14 kDa subunit Replication protein A 32 kDa subunit Replication protein A 70 kDa DNA-binding subunit SUMO-conjugating enzyme UBC9 Small ubiquitin-related modifier 1 Small ubiquitin-related modifier 2 Small ubiquitin-related modifier 3 UV excision repair protein RAD23 homolog A UV excision repair protein RAD23 homolog B Ubiquitin carboxyl-terminal hydrolase 45 Ubiquitin-conjugating enzyme E2 N Ubiquitin-conjugating enzyme E2 variant 2 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O75925 P07992 P09874 P0CG47 P0CG48 P15927 P18074 P19447 P23025 P27694 P28715 P32780 P35244 P41208 P50613 P51946 P51948 P54725 P54727 P55854 P61088 P61956 P62877 P62979 P62987 P63165 P63279 Q01831 Q13619 Q13620 Q13888 Q13889 Q15819 Q16531 Q6ZNA4 Q6ZYL4 Q70EL2 Q86WJ1 Q92466 Q92759 Q92889 Q9UGN5 Q9Y6X2	ADPRT ADPRT2 ADPRTL2 ALC1 BLU BTF2 BTF2P44 C6orf175 CAK CAK1 CALT CAP35 CCNH CDK7 CDKN7 CEN2 CETN2 CHD1L CUL4A CUL4B DDB1 DDB2 DDXBP1 ERCC1 ERCC11 ERCC2 ERCC3 ERCC4 ERCC5 ERCM2 GTF2H1 GTF2H2 GTF2H3 GTF2H4 GTF2H5 KIAA0695 MAT1 MMS2 MNAT1 MO15 PARP1 PARP2 PIAS1 PIAS3 PPOL RAD23A RAD23B RBX1 REPA1 REPA2 REPA3 RNF111 RNF66 RNF75 ROC1 RPA1 RPA14 RPA2 RPA3 RPA32 RPA34 RPA70 RPS27A SMT3A SMT3B SMT3C SMT3H1 SMT3H2 SMT3H3 STK1 SUMO1 SUMO2 SUMO3 TTDA UBA52 UBA80 UBB UBC UBC9 UBCE9 UBCEP1 UBCEP2 UBE2I UBE2N UBE2V2 UBL1 UEV2 USP45 XAP1 XPA XPAC XPB XPBC XPC XPCC XPD XPDC XPF XPG XPGC	Homo sapiens (human)
Formation of HIV-1 elongation complex containing HIV-1 Tat	CDK-activating kinase assembly factor MAT1 Cyclin-H Cyclin-T1 Cyclin-dependent kinase 7 Cyclin-dependent kinase 9 DNA-directed RNA polymerase II subunit RPB11-a DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 Elongin-A2 Elongin-A Elongin-B Elongin-C FACT complex subunit SPT16 FACT complex subunit SSRP1 General transcription and DNA repair factor IIH helicase subunit XPD General transcription and DNA repair factor IIH helicase/translocase subunit XPB General transcription factor IIF subunit 1 General transcription factor IIF subunit 2 General transcription factor IIH subunit 1 General transcription factor IIH subunit 2 General transcription factor IIH subunit 3 General transcription factor IIH subunit 4 General transcription factor IIH subunit 5 Negative elongation factor A Negative elongation factor B Negative elongation factor C/D Negative elongation factor E Nuclear cap-binding protein subunit 1 Nuclear cap-binding protein subunit 2 Protein Tat RNA polymerase II elongation factor ELL RNA polymerase II subunit A C-terminal domain phosphatase Transcription elongation factor A protein 1 Transcription elongation factor SPT4 Transcription elongation factor SPT5	O00267 O15514 O60563 P04608 P13984 P18074 P18615 P19387 P19388 P19447 P23193 P24928 P30876 P32780 P35269 P36954 P50613 P50750 P51946 P51948 P52298 P52434 P52435 P53803 P55199 P61218 P62487 P62875 P63272 Q08945 Q09161 Q13888 Q13889 Q14241 Q15369 Q15370 Q6ZYL4 Q8IXH7 Q8IYF1 Q8WX92 Q92759 Q9H3P2 Q9Y5B0 Q9Y5B9	BTF2 BTF2P44 C19orf17 C6orf175 CAK CAK1 CAP35 CBP20 CBP80 CCNH CCNT1 CDC2L4 CDK7 CDK9 CDKN7 COBRA1 CTDP1 ELL ELOA ELOA2 ELOB ELOC ERCC2 ERCC3 FACT140 FACT80 FACTP140 FCP1 GTF2F1 GTF2F2 GTF2H1 GTF2H2 GTF2H3 GTF2H4 GTF2H5 GTF2S KIAA1182 MAT1 MNAT1 MO15 NCBP NCBP1 NCBP2 NELFA NELFB NELFCD NELFD NELFE POLR2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J1 POLR2K POLR2L POLRF RAP30 RAP74 RD RDBP RNF66 RPB7 SPT4H SPT5 SPT5H SSRP1 STK1 SUPT16H SUPT4H SUPT4H1 SUPT5H TAK TCEA1 TCEB1 TCEB2 TCEB3 TCEB3B TCEB3L TFIIS TH1 TH1L TTDA WHSC2 XPB XPBC XPD XPDC tat	Homo sapiens (human)
Formation of HIV elongation complex in the absence of HIV Tat	CDK-activating kinase assembly factor MAT1 Cyclin-H Cyclin-K Cyclin-T1 Cyclin-T2 Cyclin-dependent kinase 7 Cyclin-dependent kinase 9 DNA-directed RNA polymerase II subunit RPB11-a DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 Elongin-A2 Elongin-A Elongin-B Elongin-C FACT complex subunit SPT16 FACT complex subunit SSRP1 General transcription and DNA repair factor IIH helicase subunit XPD General transcription and DNA repair factor IIH helicase/translocase subunit XPB General transcription factor IIF subunit 1 General transcription factor IIF subunit 2 General transcription factor IIH subunit 1 General transcription factor IIH subunit 2 General transcription factor IIH subunit 3 General transcription factor IIH subunit 4 General transcription factor IIH subunit 5 Negative elongation factor A Negative elongation factor B Negative elongation factor C/D Negative elongation factor E Nuclear cap-binding protein subunit 1 Nuclear cap-binding protein subunit 2 RNA polymerase II elongation factor ELL RNA polymerase II subunit A C-terminal domain phosphatase Transcription elongation factor A protein 1 Transcription elongation factor SPT4 Transcription elongation factor SPT5	O00267 O15514 O60563 O60583 O75909 P13984 P18074 P18615 P19387 P19388 P19447 P23193 P24928 P30876 P32780 P35269 P36954 P50613 P50750 P51946 P51948 P52298 P52434 P52435 P53803 P55199 P61218 P62487 P62875 P63272 Q08945 Q09161 Q13888 Q13889 Q14241 Q15369 Q15370 Q6ZYL4 Q8IXH7 Q8IYF1 Q8WX92 Q92759 Q9H3P2 Q9Y5B0 Q9Y5B9	BTF2 BTF2P44 C19orf17 C6orf175 CAK CAK1 CAP35 CBP20 CBP80 CCNH CCNK CCNT1 CCNT2 CDC2L4 CDK7 CDK9 CDKN7 COBRA1 CPR4 CTDP1 ELL ELOA ELOA2 ELOB ELOC ERCC2 ERCC3 FACT140 FACT80 FACTP140 FCP1 GTF2F1 GTF2F2 GTF2H1 GTF2H2 GTF2H3 GTF2H4 GTF2H5 GTF2S KIAA1182 MAT1 MNAT1 MO15 NCBP NCBP1 NCBP2 NELFA NELFB NELFCD NELFD NELFE POLR2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J1 POLR2K POLR2L POLRF RAP30 RAP74 RD RDBP RNF66 RPB7 SPT4H SPT5 SPT5H SSRP1 STK1 SUPT16H SUPT4H SUPT4H1 SUPT5H TAK TCEA1 TCEB1 TCEB2 TCEB3 TCEB3B TCEB3L TFIIS TH1 TH1L TTDA WHSC2 XPB XPBC XPD XPDC	Homo sapiens (human)
Formation of ATP by chemiosmotic coupling	ATP synthase F(0) complex subunit B1, mitochondrial ATP synthase F(0) complex subunit C1, mitochondrial ATP synthase F(0) complex subunit C2, mitochondrial ATP synthase F(0) complex subunit C3, mitochondrial ATP synthase protein 8 ATP synthase subunit O, mitochondrial ATP synthase subunit a ATP synthase subunit alpha, mitochondrial ATP synthase subunit beta, mitochondrial ATP synthase subunit d, mitochondrial ATP synthase subunit delta, mitochondrial ATP synthase subunit e, mitochondrial ATP synthase subunit epsilon, mitochondrial ATP synthase subunit f, mitochondrial ATP synthase subunit g, mitochondrial ATP synthase subunit gamma, mitochondrial ATP synthase subunit s, mitochondrial ATP synthase-coupling factor 6, mitochondrial	O75947 O75964 P00846 P03928 P05496 P06576 P18859 P24539 P25705 P30049 P36542 P48047 P48201 P56134 P56381 P56385 Q06055 Q99766	ATP5A ATP5A1 ATP5AL2 ATP5B ATP5C ATP5C1 ATP5CL1 ATP5D ATP5E ATP5F1 ATP5F1A ATP5F1B ATP5F1C ATP5F1D ATP5F1E ATP5G1 ATP5G2 ATP5G3 ATP5H ATP5I ATP5J ATP5J2 ATP5JL ATP5K ATP5L ATP5MC1 ATP5MC2 ATP5MC3 ATP5ME ATP5MF ATP5MG ATP5O ATP5PB ATP5PD ATP5PF ATP5PO ATP5S ATP6 ATP8 ATPASE6 ATPASE8 ATPM ATPMB ATPO ATPSB ATPW DMAC2L MT-ATP6 MT-ATP8 MTATP6 MTATP8	Homo sapiens (human)
Folding of actin by CCT/TriC	Actin, cytoplasmic 1 T-complex protein 1 subunit alpha T-complex protein 1 subunit beta T-complex protein 1 subunit delta T-complex protein 1 subunit epsilon T-complex protein 1 subunit eta T-complex protein 1 subunit gamma T-complex protein 1 subunit theta T-complex protein 1 subunit zeta-2 T-complex protein 1 subunit zeta	P17987 P40227 P48643 P49368 P50990 P50991 P60709 P78371 Q92526 Q99832	99D8.1 ACTB C21orf112 CCT1 CCT2 CCT3 CCT4 CCT5 CCT6 CCT6A CCT6B CCT7 CCT8 CCTA CCTB CCTD CCTE CCTG CCTH CCTQ CCTZ KIAA0002 KIAA0098 NIP7-1 SRB TCP1 TRIC5	Homo sapiens (human)
Ficolins bind to repetitive carbohydrate structures on the target cell surface	Ficolin-1 Ficolin-2 Ficolin-3 Mannan-binding lectin serine protease 1	O00602 O75636 P48740 Q15485	CRARF CRARF1 FCN1 FCN2 FCN3 FCNH FCNL FCNM HAKA1 MASP1 PRSS5	Homo sapiens (human)	G49108TO G57321FI
Fibronectin matrix formation	Carcinoembryonic antigen-related cell adhesion molecule 1 Carcinoembryonic antigen-related cell adhesion molecule 6 Carcinoembryonic antigen-related cell adhesion molecule 8 Fibronectin Integrin alpha-5 Integrin beta-1	P02751 P05556 P08648 P13688 P31997 P40199	BGP BGP1 CEACAM1 CEACAM6 CEACAM8 CGM6 FN FN1 FNRA FNRB ITGA5 ITGB1 MDF2 MSK12 NCA	Homo sapiens (human)
Fc epsilon receptor (FCERI) signaling	High affinity immunoglobulin epsilon receptor subunit alpha High affinity immunoglobulin epsilon receptor subunit beta High affinity immunoglobulin epsilon receptor subunit gamma IGHV7-81 protein Immunoglobulin heavy constant epsilon Immunoglobulin heavy variable 1-2 Immunoglobulin heavy variable 1-46 Immunoglobulin heavy variable 1-69 Immunoglobulin heavy variable 2-5 Immunoglobulin heavy variable 2-70 Immunoglobulin heavy variable 3-11 Immunoglobulin heavy variable 3-13 Immunoglobulin heavy variable 3-23 Immunoglobulin heavy variable 3-30 Immunoglobulin heavy variable 3-33 Immunoglobulin heavy variable 3-48 Immunoglobulin heavy variable 3-53 Immunoglobulin heavy variable 3-7 Immunoglobulin heavy variable 3-9 Immunoglobulin heavy variable 4-34 Immunoglobulin heavy variable 4-39 Immunoglobulin heavy variable 4-59 Immunoglobulin kappa constant Immunoglobulin kappa variable 1-12 Immunoglobulin kappa variable 1-16 Immunoglobulin kappa variable 1-17 Immunoglobulin kappa variable 1-33 Immunoglobulin kappa variable 1-39 Immunoglobulin kappa variable 1-5 Immunoglobulin kappa variable 1D-12 Immunoglobulin kappa variable 1D-16 Immunoglobulin kappa variable 1D-33 Immunoglobulin kappa variable 1D-39 Immunoglobulin kappa variable 2-28 Immunoglobulin kappa variable 2-29 Immunoglobulin kappa variable 2-30 Immunoglobulin kappa variable 2D-28 Immunoglobulin kappa variable 2D-30 Immunoglobulin kappa variable 2D-40 Immunoglobulin kappa variable 3-11 Immunoglobulin kappa variable 3-15 Immunoglobulin kappa variable 3-20 Immunoglobulin kappa variable 3D-20 Immunoglobulin kappa variable 4-1 Immunoglobulin kappa variable 5-2 Immunoglobulin lambda constant 1 Immunoglobulin lambda constant 2 Immunoglobulin lambda constant 3 Immunoglobulin lambda constant 6 Immunoglobulin lambda constant 7 Immunoglobulin lambda variable 1-40 Immunoglobulin lambda variable 1-44 Immunoglobulin lambda variable 1-47 Immunoglobulin lambda variable 1-51 Immunoglobulin lambda variable 2-11 Immunoglobulin lambda variable 2-14 Immunoglobulin lambda variable 2-23 Immunoglobulin lambda variable 2-8 Immunoglobulin lambda variable 3-19 Immunoglobulin lambda variable 3-1 Immunoglobulin lambda variable 3-21 Immunoglobulin lambda variable 3-25 Immunoglobulin lambda variable 3-27 Immunoglobulin lambda variable 6-57 Immunoglobulin lambda variable 7-43 Immunolglobulin kappa light chain variable region L22 (Fragment) Tyrosine-protein kinase Lyn Tyrosine-protein kinase SYK UGa8H (Fragment) V1-11 protein (Fragment) V1-13 protein (Fragment) V1-16 protein (Fragment) V1-20 protein (Fragment) V1-3 protein (Fragment) V1-5 protein (Fragment) V1-7 protein (Fragment) V1-9 protein (Fragment) V2-11 protein (Fragment) V2-15 protein (Fragment) V2-17 protein (Fragment) V2-19 protein (Fragment) V2-8 protein (Fragment) V3-2 protein (Fragment) V3-3 protein (Fragment) V3-4 protein (Fragment) V4-1 protein (Fragment) V4-2 protein (Fragment) V4-6 protein (Fragment) V5-1 protein (Fragment) V5-4 protein (Fragment) V5-6 protein (Fragment)	A0A075B6P5 A0A075B6S6 A0A0C4DH25 A0A0C4DH73 A0M8Q6 A2KUC3 A2NJV5 A2NXD2 P01593 P01594 P01597 P01599 P01601 P01602 P01611 P01614 P01615 P01619 P01624 P01699 P01700 P01701 P01703 P01704 P01705 P01706 P01709 P01714 P01715 P01717 P01718 P01721 P01742 P01743 P01762 P01763 P01764 P01766 P01767 P01768 P01772 P01780 P01782 P01814 P01817 P01824 P01825 P01834 P01854 P04211 P04430 P04432 P04433 P06310 P06312 P06315 P06331 P07948 P0CF74 P0CG04 P0DOY2 P0DOY3 P12319 P23083 P30273 P43405 P80748 Q01362 Q5NV61 Q5NV62 Q5NV64 Q5NV65 Q5NV66 Q5NV67 Q5NV68 Q5NV69 Q5NV75 Q5NV79 Q5NV80 Q5NV81 Q5NV82 Q5NV83 Q5NV84 Q5NV85 Q5NV86 Q5NV87 Q5NV89 Q5NV90 Q5NV91 Q5NV92 Q6PIL0	APY FCE1A FCER1A FCER1B FCER1G IGER IGHE IGHV IGHV1-2 IGHV1-46 IGHV1-69 IGHV2-5 IGHV2-70 IGHV3-11 IGHV3-13 IGHV3-23 IGHV3-30 IGHV3-33 IGHV3-48 IGHV3-53 IGHV3-7 IGHV3-9 IGHV4-34 IGHV4-39 IGHV4-59 IGHV7-81 IGKC IGKV1-12 IGKV1-16 IGKV1-17 IGKV1-33 IGKV1-39 IGKV1-5 IGKV1D-12 IGKV1D-16 IGKV1D-33 IGKV1D-39 IGKV2-28 IGKV2-29 IGKV2-30 IGKV2D-28 IGKV2D-30 IGKV2D-40 IGKV3-11 IGKV3-15 IGKV3-20 IGKV3D-20 IGKV4-1 IGKV5-2 IGLC1 IGLC2 IGLC3 IGLC6 IGLC7 IGLV IGLV1-40 IGLV1-44 IGLV1-47 IGLV1-51 IGLV2-11 IGLV2-14 IGLV2-23 IGLV2-8 IGLV3-1 IGLV3-19 IGLV3-21 IGLV3-25 IGLV3-27 IGLV6-57 IGLV7-43 JTK8 LYN MS4A2 SYK V1-11 V1-13 V1-16 V1-20 V1-3 V1-5 V1-7 V1-9 V2-11 V2-15 V2-17 V2-19 V2-8 V3-2 V3-3 V3-4 V4-1 V4-2 V4-6 V5-1 V5-4 V5-6	Homo sapiens (human)
Fatty acyl-CoA biosynthesis	(3R)-3-hydroxyacyl-CoA dehydrogenase 3-oxoacyl-[acyl-carrier-protein] reductase ATP-citrate synthase ATPase MORC2 Acetyl-CoA carboxylase 1 Fatty acid synthase Hydroxyacyl-thioester dehydratase type 2, mitochondrial Long-chain fatty acid transport protein 2 Lysosomal thioesterase PPT2 Palmitoyl-protein thioesterase 1 S-acyl fatty acid synthase thioesterase, medium chain Stearoyl-CoA desaturase 5 Stearoyl-CoA desaturase	O00767 O14975 P49327 P50897 P53396 P86397 Q13085 Q86SK9 Q8N4T8 Q92506 Q9NV23 Q9UMR5 Q9Y6X9	ACAC ACACA ACC1 ACCA ACLY ACOD4 ACSVL1 CBR4 CLN1 FABGL FACVL1 FADS5 FAS FASN FATP2 HKE6 HSD17B8 HTD2 KIAA0852 MORC2 OLAH PPT PPT1 PPT2 RING2 SCD SCD1 SCD2 SCD4 SCD5 SCDOS SDR30C1 SDR45C1 SLC27A2 THEDC1 VLACS ZCWCC1	Homo sapiens (human)
Fatty acids	Cytochrome P450 2A13 Cytochrome P450 2A7 Cytochrome P450 2B6 Cytochrome P450 2D6 Cytochrome P450 2F1 Cytochrome P450 2J2 Cytochrome P450 4A11 Cytochrome P450 4A22 Cytochrome P450 4B1 Cytochrome P450 4F11 Cytochrome P450 4F12 Cytochrome P450 4F2 Cytochrome P450 4F3 Cytochrome P450 4F8 Ultra-long-chain fatty acid omega-hydroxylase	P10635 P13584 P20813 P20853 P24903 P51589 P78329 P98187 Q02928 Q08477 Q16696 Q5TCH4 Q6NT55 Q9HBI6 Q9HCS2	CYP2A13 CYP2A7 CYP2B6 CYP2D6 CYP2DL1 CYP2F1 CYP2J2 CYP4A11 CYP4A2 CYP4A22 CYP4B1 CYP4F11 CYP4F12 CYP4F2 CYP4F22 CYP4F3 CYP4F8 LTB4H	Homo sapiens (human)
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 Free fatty acid receptor 1 Guanine nucleotide-binding protein G(q) subunit alpha Guanine nucleotide-binding protein subunit alpha-11 Guanine nucleotide-binding protein subunit alpha-14 Guanine nucleotide-binding protein subunit alpha-15	O14842 O95837 P29992 P30679 P50148 Q00722 Q01970 Q9NQ66	FFAR1 GA11 GAQ GNA11 GNA14 GNA15 GNA16 GNAQ GPR40 KIAA0581 PLCB1 PLCB2 PLCB3	Homo sapiens (human)
FasL/ CD95L signaling	Caspase-10 Caspase-8 FAS-associated death domain protein Tumor necrosis factor ligand superfamily member 6 Tumor necrosis factor receptor superfamily member 6	P25445 P48023 Q13158 Q14790 Q92851	APT1 APT1LG1 CASP10 CASP8 CD95L FADD FAS FAS1 FASL FASLG MCH4 MCH5 MORT1 TNFRSF6 TNFSF6	Homo sapiens (human)
Fanconi Anemia Pathway	5' exonuclease Apollo ATR-interacting protein Centromere protein S Centromere protein X Crossover junction endonuclease EME1 Crossover junction endonuclease MUS81 DNA cross-link repair 1A protein DNA excision repair protein ERCC-1 DNA polymerase nu DNA repair endonuclease XPF E3 ubiquitin-protein ligase FANCL Fanconi anemia core complex-associated protein 100 Fanconi anemia core complex-associated protein 20 Fanconi anemia core complex-associated protein 24 Fanconi anemia group A protein Fanconi anemia group B protein Fanconi anemia group C protein Fanconi anemia group D2 protein Fanconi anemia group E protein Fanconi anemia group F protein Fanconi anemia group G protein Fanconi anemia group I protein Fanconi anemia group M protein Fanconi-associated nuclease 1 Polyubiquitin-B Polyubiquitin-C Probable crossover junction endonuclease EME2 Replication protein A 14 kDa subunit Replication protein A 32 kDa subunit Replication protein A 70 kDa DNA-binding subunit Serine/threonine-protein kinase ATR Structure-specific endonuclease subunit SLX1 Structure-specific endonuclease subunit SLX4 Ubiquitin carboxyl-terminal hydrolase 1 Ubiquitin-conjugating enzyme E2 T Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein WD repeat-containing protein 48	A4GXA9 A8MT69 O15287 O15360 O94782 P07992 P0CG47 P0CG48 P15927 P27694 P35244 P62979 P62987 Q00597 Q0VG06 Q13535 Q6NZ36 Q6PJP8 Q7Z5Q5 Q8IY92 Q8IYD8 Q8N2Z9 Q8NB91 Q8TAF3 Q8WXE1 Q92889 Q96AY2 Q96NY9 Q9BQ83 Q9BTP7 Q9BXW9 Q9H816 Q9HB96 Q9NPD8 Q9NPI8 Q9NVI1 Q9NW38 Q9Y2M0	AGS1 APITD1 ATR ATRIP BTBD12 C17orf70 C19orf40 C1orf86 CENPS CENPX DCLRE1A DCLRE1B EME1 EME2 ERCC1 ERCC11 ERCC4 FAA FAAP10 FAAP100 FAAP16 FAAP20 FAAP24 FAC FACA FACC FACD FACE FAN1 FANCA FANCB FANCC FANCD2 FANCE FANCF FANCG FANCH FANCI FANCL FANCM FRP1 GIYD1 GIYD2 KIAA0086 KIAA1018 KIAA1449 KIAA1596 KIAA1784 KIAA1794 KIAA1987 MHF1 MHF2 MMS4 MTMR15 MUS81 PHF9 POLN REPA1 REPA2 REPA3 RPA1 RPA14 RPA2 RPA3 RPA32 RPA34 RPA70 RPS27A SLX1 SLX1A SLX1B SLX4 SNM1 SNM1A SNM1B STRA13 UAF1 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 UBE2T USP1 WDR48 XPF XRCC9	Homo sapiens (human)
Factors involved in megakaryocyte development and platelet production	A-kinase anchor protein 1, mitochondrial A-kinase anchor protein 10, mitochondrial CDK5 and ABL1 enzyme substrate 1 CDK5 and ABL1 enzyme substrate 2 Cell division control protein 42 homolog Cellular tumor antigen p53 Chromobox protein homolog 5 Cyclin-dependent kinase 2 Cyclin-dependent kinase 5 DNA repair protein RAD51 homolog 2 DNA repair protein RAD51 homolog 3 Dedicator of cytokinesis protein 10 Dedicator of cytokinesis protein 11 Dedicator of cytokinesis protein 1 Dedicator of cytokinesis protein 2 Dedicator of cytokinesis protein 3 Dedicator of cytokinesis protein 4 Dedicator of cytokinesis protein 5 Dedicator of cytokinesis protein 6 Dedicator of cytokinesis protein 7 Dedicator of cytokinesis protein 8 Dedicator of cytokinesis protein 9 EH domain-containing protein 1 EH domain-containing protein 2 EH domain-containing protein 3 Endothelial transcription factor GATA-2 Erythroid transcription factor F-actin-capping protein subunit alpha-1 F-actin-capping protein subunit alpha-2 F-actin-capping protein subunit beta F-actin-uncapping protein LRRC16A GTP Hemoglobin subunit beta Hemoglobin subunit delta Hemoglobin subunit epsilon Hemoglobin subunit gamma-1 Hemoglobin subunit gamma-2 Histone H3.1 Histone H3.2 Histone H3.3 Histone deacetylase 1 Histone deacetylase 2 Inositol-tetrakisphosphate 1-kinase Interferon alpha-1/13 Interferon alpha-10 Interferon alpha-14 Interferon alpha-16 Interferon alpha-17 Interferon alpha-21 Interferon alpha-2 Interferon alpha-4 Interferon alpha-5 Interferon alpha-6 Interferon alpha-7 Interferon alpha-8 Interferon beta Interferon regulatory factor 1 Interferon regulatory factor 2 Lysine-specific histone demethylase 1A Mitofusin-1 Mitofusin-2 PHD finger protein 21A Paired amphipathic helix protein Sin3a Probable JmjC domain-containing histone demethylation protein 2C REST corepressor 1 Rabenosyn-5 Ras-related C3 botulinum toxin substrate 1 Ras-related protein Rab-5A SH2B adapter protein 1 SH2B adapter protein 2 SH2B adapter protein 3 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related Trans-acting T-cell-specific transcription factor GATA-3 Transcription factor GATA-4 Transcription factor GATA-5 Transcription factor GATA-6 Transcription factor MafF Transcription factor MafG Transcription factor MafK Transcription factor NF-E2 45 kDa subunit Transcriptional activator Myb Tyrosine-protein kinase ABL1 Tyrosine-protein kinase JAK2 Vacuolar protein sorting-associated protein 45 Wee1-like protein kinase Zinc finger protein ZFPM1 Zinc finger protein ZFPM2 [F-actin]-monooxygenase MICAL1 cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit gamma cAMP-dependent protein kinase type I-alpha regulatory subunit cAMP-dependent protein kinase type I-beta regulatory subunit cAMP-dependent protein kinase type II-alpha regulatory subunit cAMP-dependent protein kinase type II-beta regulatory subunit	O14492 O15315 O15525 O43502 O43572 O60341 O60674 O60675 O95140 P00519 P01562 P01563 P01566 P01567 P01568 P01569 P01570 P01571 P01574 P02042 P02100 P04637 P05013 P05014 P05015 P10242 P10644 P10914 P13861 P14316 P15976 P17612 P20339 P22612 P22694 P23769 P23771 P24941 P30291 P31321 P31323 P32881 P43694 P45973 P47755 P47756 P52907 P60953 P63000 P68431 P68871 P69891 P69892 P84243 Q00535 Q13547 Q13572 Q14185 Q15652 Q16621 Q5JSL3 Q5VZK9 Q71DI3 Q8IWA4 Q8IX07 Q8IZD9 Q8N1I0 Q8NF50 Q8TDN4 Q8TDZ2 Q8WW38 Q92608 Q92667 Q92769 Q92908 Q96BD5 Q96BY6 Q96HP0 Q96N67 Q96ST3 Q9BTV7 Q9BWX5 Q9BZ29 Q9H1K0 Q9H4M9 Q9H7D0 Q9NRF2 Q9NRW7 Q9NZN3 Q9NZN4 Q9P0W2 Q9UIJ7 Q9UKL0 Q9ULX9 Q9UQQ2	ABL ABL1 AK3 AK3L1 AK6 AKAP1 AKAP10 AKAP149 AKL3L AOF2 APS BHC80 BRAF35 C20orf150 CABLES CABLES1 CABLES2 CAPZA1 CAPZA2 CAPZB CARMIL CARMIL1 CBX5 CDC42 CDK2 CDK5 CDKN2 CDKN5 CPRP1 DOCK1 DOCK10 DOCK11 DOCK2 DOCK3 DOCK4 DOCK5 DOCK6 DOCK7 DOCK8 DOCK9 EHD1 EHD2 EHD3 ERYF1 FOG1 FOG2 GATA1 GATA2 GATA3 GATA4 GATA5 GATA6 GF1 H3-3A H3-3B H3.3A H3.3B H3C1 H3C10 H3C11 H3C12 H3C13 H3C14 H3C15 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 H3F2 H3F3 H3F3A H3F3B H3FA H3FB H3FC HIST1H3C H3FD H3FF H3FH H3FI H3FJ H3FK H3FL H3FM HBB HBD HBE HBE1 HBG1 HBG2 HDAC1 HDAC2 HIST1H3A HIST1H3B HIST1H3D HIST1H3E HIST1H3F HIST1H3G HIST1H3H HIST1H3I HIST1H3J HIST2H3A HIST2H3C HIST2H3D HMG20B HMGX2 HMGXB2 HP1A IFB IFNA1 IFNA10 IFNA13 IFNA14 IFNA16 IFNA17 IFNA2 IFNA21 IFNA2A IFNA2B IFNA2C IFNA4 IFNA5 IFNA6 IFNA7 IFNA8 IFNB IFNB1 IRF1 IRF2 ITPK1 JAK2 JHDM2C JMJD1C JTK7 KDM1 KDM1A KIAA0071 KIAA0209 KIAA0214 KIAA0299 KIAA0601 KIAA0694 KIAA0716 KIAA1058 KIAA1299 KIAA1380 KIAA1395 KIAA1696 KIAA1771 LNK LRRC16 LRRC16A LSD1 MAFF MAFG MAFK MFN1 MFN2 MICAL MICAL1 MOCA MYB NFE2 NICAL P53 PAST PAST1 PAST2 PAST3 PHF21A PKACA PKR1 PKR2 PRKA1 PRKACA PRKACB PRKACG PRKAR1 PRKAR1A PRKAR1B PRKAR2 PRKAR2A PRKAR2B PSSALRE RAB5 RAB5A RAC1 RAD51B RAD51C RAD51L1 RAD51L2 RBSN RCOR RCOR1 REC2 RPD3L1 SH2B SH2B1 SH2B2 SH2B3 SIN3A SMARCE1R TC25 TP53 TRIP8 TSE1 VPS45 VPS45A VPS45B WEE1 ZFN89A ZFPM1 ZFPM2 ZFYVE20 ZIZ1 ZIZ2 ZIZ3 ZNF89B	Homo sapiens (human)
FRS-mediated FGFR4 signaling	Beta-klotho Fibroblast growth factor 16 Fibroblast growth factor 18 Fibroblast growth factor 19 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 4 Fibroblast growth factor 6 Fibroblast growth factor 9 Fibroblast growth factor receptor 4 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor substrate 3 GTPase HRas GTPase NRas Son of sevenless homolog 1 Tyrosine-protein phosphatase non-receptor type 11	O43320 O43559 O76093 O95750 P01111 P01112 P05230 P08620 P09038 P10767 P22455 P31371 Q06124 Q07889 Q86Z14 Q8WU20 Q9GZV9 Q9NP95	FGF1 FGF16 FGF18 FGF19 FGF2 FGF20 FGF23 FGF4 FGF6 FGF9 FGFA FGFB FGFR4 FRS2 FRS3 HRAS HRAS1 HST HST2 HSTF1 HSTF2 HYPF JTK2 KLB KS3 NRAS PTP2C PTPN11 SHPTP2 SOS1 TKF	Homo sapiens (human)
FRS-mediated FGFR3 signaling	Fibroblast growth factor 16 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 4 Fibroblast growth factor 9 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor substrate 3 GTPase HRas GTPase NRas Son of sevenless homolog 1 Tyrosine-protein phosphatase non-receptor type 11	O43320 O43559 O76093 P01111 P01112 P05230 P08620 P09038 P31371 Q06124 Q07889 Q8WU20 Q9GZV9 Q9NP95	FGF1 FGF16 FGF18 FGF2 FGF20 FGF23 FGF4 FGF9 FGFA FGFB FRS2 FRS3 HRAS HRAS1 HST HSTF1 HYPF KS3 NRAS PTP2C PTPN11 SHPTP2 SOS1	Homo sapiens (human)
FRS-mediated FGFR2 signaling	Fibroblast growth factor 10 Fibroblast growth factor 16 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 22 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor 4 Fibroblast growth factor 6 Fibroblast growth factor 7 Fibroblast growth factor 9 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor substrate 3 GTPase HRas GTPase NRas Son of sevenless homolog 1 Tyrosine-protein phosphatase non-receptor type 11	O15520 O43320 O43559 O76093 P01111 P01112 P05230 P08620 P09038 P10767 P11487 P21781 P31371 Q06124 Q07889 Q8WU20 Q9GZV9 Q9HCT0 Q9NP95	FGF1 FGF10 FGF16 FGF18 FGF2 FGF20 FGF22 FGF23 FGF3 FGF4 FGF6 FGF7 FGF9 FGFA FGFB FRS2 FRS3 HRAS HRAS1 HST HST2 HSTF1 HSTF2 HYPF INT2 KGF KS3 NRAS PTP2C PTPN11 SHPTP2 SOS1	Homo sapiens (human)
FRS-mediated FGFR1 signaling	Fibroblast growth factor 10 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 22 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor 4 Fibroblast growth factor 6 Fibroblast growth factor 9 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor substrate 3 GTPase HRas GTPase NRas Son of sevenless homolog 1 Tyrosine-protein phosphatase non-receptor type 11	O15520 O43559 P01111 P01112 P05230 P08620 P09038 P10767 P11487 P31371 Q06124 Q07889 Q8WU20 Q9GZV9 Q9HCT0 Q9NP95	FGF1 FGF10 FGF2 FGF20 FGF22 FGF23 FGF3 FGF4 FGF6 FGF9 FGFA FGFB FRS2 FRS3 HRAS HRAS1 HST HST2 HSTF1 HSTF2 HYPF INT2 KS3 NRAS PTP2C PTPN11 SHPTP2 SOS1	Homo sapiens (human)
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes	ATP-binding cassette sub-family A member 6 Agouti-related protein Ataxin-3 Catalase E3 ubiquitin-protein ligase TRIM63 F-box only protein 32 Forkhead box protein O1 Forkhead box protein O3 Forkhead box protein O4 Forkhead box protein O6 Glucocorticoid receptor Glucose-6-phosphatase catalytic subunit 1 Hexokinase-4 Histone deacetylase 1 Histone deacetylase 2 Insulin-like growth factor-binding protein 1 Insulin Mothers against decapentaplegic homolog 2 Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 4 NAD-dependent protein deacetylase sirtuin-3, mitochondrial Paired amphipathic helix protein Sin3a Peroxisome proliferator-activated receptor gamma coactivator 1-alpha Phosphoenolpyruvate carboxykinase, cytosolic [GTP] Plexin-A4 Pro-neuropeptide Y Pro-opiomelanocortin Resistin Sterol regulatory element-binding protein 1 Superoxide dismutase [Mn], mitochondrial	A8MYZ6 O00253 O43524 P01189 P01303 P01308 P04040 P04150 P04179 P08833 P35557 P35558 P35575 P36956 P54252 P84022 P98177 Q12778 Q13485 Q13547 Q15796 Q8N139 Q92769 Q969P5 Q969Q1 Q96ST3 Q9HCM2 Q9HD89 Q9NTG7 Q9UBK2	ABCA6 AFX AFX1 AGRP AGRT ART ATX3 ATXN3 BHLHD1 CAT DPC4 FBXO32 FIZZ3 FKHR FKHRL1 FOXO1 FOXO1A FOXO3 FOXO3A FOXO4 FOXO6 G6PC G6PC1 G6PT GCK GRL HDAC1 HDAC2 HXCP1 IBP1 IGFBP1 INS IRF KIAA1550 LEM6 MADH2 MADH3 MADH4 MADR2 MJD MJD1 MLLT7 MURF1 NPY NR3C1 PCK1 PEPCK1 PGC1 PGC1A PLXNA4 PLXNA4A PLXNA4B POMC PPARGC1 PPARGC1A RETN RNF28 RPD3L1 RSTN SCA3 SIN3A SIR2L3 SIRT3 SMAD2 SMAD3 SMAD4 SMRZ SOD2 SREBF1 SREBP1 TRIM63	Homo sapiens (human)
FOXO-mediated transcription of cell death genes	B-cell lymphoma 6 protein Bcl-2-binding component 3, isoforms 1/2 Bcl-2-like protein 11 CREB-binding protein Cbp/p300-interacting transactivator 2 DNA damage-inducible transcript 3 protein Forkhead box protein O1 Forkhead box protein O3 Forkhead box protein O4 Histone acetyltransferase p300 Nuclear transcription factor Y subunit alpha Nuclear transcription factor Y subunit beta Nuclear transcription factor Y subunit gamma Serine/threonine-protein kinase PINK1, mitochondrial Serine/threonine-protein kinase STK11 Tumor necrosis factor ligand superfamily member 6	O43521 O43524 P23511 P25208 P35638 P41182 P48023 P98177 Q09472 Q12778 Q13952 Q15831 Q92793 Q99967 Q9BXH1 Q9BXM7	AFX AFX1 APT1LG1 BBC3 BCL2L11 BCL5 BCL6 BIM CBP CD95L CHOP CHOP10 CITED2 CREBBP DDIT3 EP300 FASL FASLG FKHR FKHRL1 FOXO1 FOXO1A FOXO3 FOXO3A FOXO4 GADD153 HAP3 LAZ3 LKB1 MLLT7 MRG1 NFYA NFYB NFYC P300 PINK1 PJS PUMA STK11 TNFSF6 ZBTB27 ZNF51	Homo sapiens (human)
FOXO-mediated transcription of cell cycle genes	Caveolin-1 Cyclin-G2 Cyclin-dependent kinase inhibitor 1 Cyclin-dependent kinase inhibitor 1B Forkhead box protein G1 Forkhead box protein O1 Forkhead box protein O3 Forkhead box protein O4 Growth arrest and DNA damage-inducible protein GADD45 alpha Growth/differentiation factor 8 Krueppel-like factor 4 Mothers against decapentaplegic homolog 2 Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 4 Poly(rC)-binding protein 4 Protein BTG1 Retinoblastoma-like protein 2	O14793 O43474 O43524 P24522 P38936 P46527 P55316 P57723 P62324 P84022 P98177 Q03135 Q08999 Q12778 Q13485 Q15796 Q16589	AFX AFX1 BTG1 CAP20 CAV CAV1 CCNG2 CDKN1 CDKN1A CDKN1B CIP1 DDIT1 DPC4 EZF FKH2 FKHL1 FKHL2 FKHL3 FKHL4 FKHR FKHRL1 FOXG1 FOXG1A FOXG1B FOXG1C FOXO1 FOXO1A FOXO3 FOXO3A FOXO4 GADD45 GADD45A GDF8 GKLF KIP1 KLF4 MADH2 MADH3 MADH4 MADR2 MDA6 MLLT7 MSTN PCBP4 PIC1 RB2 RBL2 SDI1 SMAD2 SMAD3 SMAD4 WAF1 p27	Homo sapiens (human)
FLT3 signaling through SRC family kinases	Fms-related tyrosine kinase 3 ligand Receptor-type tyrosine-protein kinase FLT3 Tyrosine-protein kinase Fyn Tyrosine-protein kinase HCK Tyrosine-protein kinase Lck Tyrosine-protein kinase SYK	P06239 P06241 P08631 P36888 P43405 P49771	CD135 FLK2 FLT3 FLT3LG FYN HCK LCK STK1 SYK	Homo sapiens (human)

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