GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **1676 - 1700** of **2090** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▼	Organism
PKR-mediated signaling	ATP-dependent RNA helicase A Alpha-synuclein Cellular tumor antigen p53 Centromere protein S Centromere protein X Cyclin-dependent kinase 1 DnaJ homolog subfamily C member 3 Double-stranded RNA-specific adenosine deaminase Dual specificity mitogen-activated protein kinase kinase 6 E3 ISG15--protein ligase HERC5 E3 ubiquitin-protein ligase ARIH1 E3 ubiquitin-protein ligase FANCL E3 ubiquitin/ISG15 ligase TRIM25 Eukaryotic translation initiation factor 2 subunit 1 Eukaryotic translation initiation factor 2 subunit 2 Eukaryotic translation initiation factor 2 subunit 3 Fanconi anemia core complex-associated protein 100 Fanconi anemia core complex-associated protein 20 Fanconi anemia core complex-associated protein 24 Fanconi anemia group A protein Fanconi anemia group B protein Fanconi anemia group C protein Fanconi anemia group E protein Fanconi anemia group F protein Fanconi anemia group G protein Fanconi anemia group M protein Heat shock 70 kDa protein 1-like Heat shock 70 kDa protein 1A Heat shock 70 kDa protein 1B Heat shock cognate 71 kDa protein Heat shock-related 70 kDa protein 2 Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Interferon-induced, double-stranded RNA-activated protein kinase Interferon-inducible double-stranded RNA-dependent protein kinase activator A Interleukin enhancer-binding factor 2 Interleukin enhancer-binding factor 3 Mitochondrial antiviral-signaling protein NF-kappa-B essential modulator Non-structural protein 1 Nucleophosmin Nucleoprotein Protein TRS1 Protein Tat RISC-loading complex subunit TARBP2 SH2/SH3 adapter protein NCK1 SUMO-conjugating enzyme UBC9 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform Signal transducer and activator of transcription 1-alpha/beta Signal transducer and activator of transcription 3 Small ubiquitin-related modifier 1 Sphingosine kinase 1 Tyrosine-protein phosphatase non-receptor type 2 Ubiquitin-like protein ISG15 Ubiquitin/ISG15-conjugating enzyme E2 L6 tRNA-dihydrouridine(20) synthase [NAD(P)+]-like	A8MT69 O14920 O14933 O15111 O15287 O15360 O75569 P03418 P03496 P04609 P04637 P05161 P05198 P06493 P06748 P0DMV8 P0DMV9 P11142 P16333 P17706 P19525 P20042 P30153 P30154 P34931 P37840 P40763 P41091 P42224 P52564 P54652 P55265 P62714 P63165 P63279 P67775 Q00597 Q08211 Q0VG06 Q12905 Q12906 Q13217 Q14258 Q15172 Q15633 Q6NZ36 Q6SVX2 Q7Z434 Q8IYD8 Q8N2Z9 Q8NB91 Q9BTP7 Q9HB96 Q9NPI8 Q9NW38 Q9NX74 Q9NYA1 Q9UII4 Q9Y4X5 Q9Y6K9	ADAR ADAR1 APITD1 APRF ARI ARIH1 C17orf70 C19orf40 C1orf86 CDC2 CDC28A CDK1 CDKN1 CEB1 CEBP1 CENPS CENPX CHUK DDX9 DHX9 DNAJC3 DRBF DSRAD DUS2 DUS2L EFP EIF2A EIF2AK2 EIF2B EIF2G EIF2S1 EIF2S2 EIF2S3 FAA FAAP10 FAAP100 FAAP16 FAAP20 FAAP24 FAC FACA FACC FACE FANCA FANCB FANCC FANCE FANCF FANCG FANCH FANCL FANCM FIP3 G1P1 G1P2 HERC5 HSC70 HSP72 HSP73 HSPA1 HSPA10 HSPA1A HSPA1B HSPA1L HSPA2 HSPA8 HSX70 IFI4 IKBKB IKBKG IKKA IKKB ILF2 ILF3 IPS1 ISG15 KIAA1271 KIAA1596 LKP MAP2K6 MAVS MEK6 MHF1 MHF2 MKK6 MOP6 MPHOSPH4 N NACP NCK NCK1 NDH2 NEMO NF45 NF90 NPM NPM1 NS P34CDC2 P53 P58IPK PACT PARK1 PHF9 PKR PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PRKMK6 PRKR PRKRA PRKRI PTPN2 PTPT RAX RNF147 SK1 SKK3 SMT3C SMT3H3 SNCA SPHK SPHK1 SPK STAT1 STAT3 STRA13 SUMO1 TARBP2 TCF16 TP53 TRBP TRIM25 TRS1 UBC9 UBCE9 UBCH7BP UBCH8 UBE2I UBE2L6 UBL1 UCRP VISA XRCC9 ZNF147 tat	Homo sapiens (human)
Formation of editosomes by ADAR proteins	Double-stranded RNA-specific adenosine deaminase Double-stranded RNA-specific editase 1	P55265 P78563	ADAR ADAR1 ADAR2 ADARB1 DRADA2 DSRAD G1P1 IFI4 RED1	Homo sapiens (human)
C6 deamination of adenosine	Double-stranded RNA-specific adenosine deaminase Double-stranded RNA-specific editase 1	P55265 P78563	ADAR ADAR1 ADAR2 ADARB1 DRADA2 DSRAD G1P1 IFI4 RED1	Homo sapiens (human)
Collagen biosynthesis and modifying enzymes	A disintegrin and metalloproteinase with thrombospondin motifs 14 A disintegrin and metalloproteinase with thrombospondin motifs 2 A disintegrin and metalloproteinase with thrombospondin motifs 3 Bone morphogenetic protein 1 Cartilage-associated protein Collagen alpha-1(I) chain Collagen alpha-1(II) chain Collagen alpha-1(III) chain Collagen alpha-1(IV) chain Collagen alpha-1(IX) chain Collagen alpha-1(V) chain Collagen alpha-1(VI) chain Collagen alpha-1(VII) chain Collagen alpha-1(VIII) chain Collagen alpha-1(X) chain Collagen alpha-1(XI) chain Collagen alpha-1(XII) chain Collagen alpha-1(XIII) chain Collagen alpha-1(XIV) chain Collagen alpha-1(XIX) chain Collagen alpha-1(XV) chain Collagen alpha-1(XVI) chain Collagen alpha-1(XVII) chain Collagen alpha-1(XVIII) chain Collagen alpha-1(XX) chain Collagen alpha-1(XXI) chain Collagen alpha-1(XXII) chain Collagen alpha-1(XXIII) chain Collagen alpha-1(XXIV) chain Collagen alpha-1(XXV) chain Collagen alpha-1(XXVI) chain Collagen alpha-1(XXVII) chain Collagen alpha-1(XXVIII) chain Collagen alpha-2(I) chain Collagen alpha-2(IV) chain Collagen alpha-2(IX) chain Collagen alpha-2(V) chain Collagen alpha-2(VI) chain Collagen alpha-2(VIII) chain Collagen alpha-2(XI) chain Collagen alpha-3(IV) chain Collagen alpha-3(IX) chain Collagen alpha-3(V) chain Collagen alpha-3(VI) chain Collagen alpha-4(IV) chain Collagen alpha-5(IV) chain Collagen alpha-5(VI) chain Collagen alpha-6(IV) chain Collagen alpha-6(VI) chain Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 Peptidyl-prolyl cis-trans isomerase B Procollagen C-endopeptidase enhancer 1 Procollagen C-endopeptidase enhancer 2 Procollagen galactosyltransferase 1 Procollagen galactosyltransferase 2 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 Prolyl 3-hydroxylase 1 Prolyl 3-hydroxylase 2 Prolyl 3-hydroxylase 3 Prolyl 4-hydroxylase subunit alpha-1 Prolyl 4-hydroxylase subunit alpha-2 Prolyl 4-hydroxylase subunit alpha-3 Protein disulfide-isomerase Serpin H1 Tolloid-like protein 1 Tolloid-like protein 2	A6NMZ7 A8TX70 O00469 O15072 O15460 O43897 O60568 O75718 O95450 P02452 P02458 P02461 P02462 P05997 P07237 P08123 P08572 P12107 P12109 P12110 P12111 P13497 P13674 P13942 P20849 P20908 P23284 P25067 P25940 P27658 P29400 P39059 P39060 P50454 P53420 Q01955 Q02388 Q02809 Q03692 Q05707 Q07092 Q14031 Q14050 Q14055 Q14993 Q15113 Q17RW2 Q2UY09 Q32P28 Q5TAT6 Q7Z4N8 Q86Y22 Q8IVL5 Q8IVL6 Q8IYK4 Q8IZC6 Q8NBJ5 Q8NFW1 Q8WXS8 Q96A83 Q96P44 Q99715 Q9BXS0 Q9P218 Q9UKZ9 Q9UMD9 Q9Y6L7	ADAMTS14 ADAMTS2 ADAMTS3 BMP1 BP180 BPAG2 C1orf17 C3orf7 CASP CBP1 CBP2 COL10A1 COL11A1 COL11A2 COL12A1 COL12A1L COL13A1 COL14A1 COL15A1 COL16A1 COL17A1 COL18A1 COL19A1 COL1A1 COL1A2 COL1AL COL20A1 COL21A1 COL22A1 COL23A1 COL24A1 COL25A1 COL26A1 COL27A1 COL28 COL28A1 COL29A1 COL2A1 COL3A1 COL4A1 COL4A2 COL4A3 COL4A4 COL4A5 COL4A6 COL5A1 COL5A2 COL5A3 COL6A1 COL6A2 COL6A3 COL6A5 COL6A6 COL7A1 COL8A1 COL8A2 COL9A1 COL9A2 COL9A3 COLGALT1 COLGALT2 COLL6 CRTAP CYPB EMID2 EMU2 ERBA2L GLT25D1 GLT25D2 GROS1 HSP47 KIAA0366 KIAA0584 KIAA0932 KIAA1510 KIAA1870 LEPRE1 LEPREL1 LEPREL2 LLH MLAT4 P3H1 P3H2 P3H3 P4HA P4HA1 P4HA2 P4HA3 P4HB PCINP PCOLC PCOLCE PCOLCE2 PCPE1 PCPE2 PCPNI PDI PDIA1 PLOD PLOD1 PLOD2 PLOD3 PO4DB PPIB SERPINH1 SERPINH2 TLL TLL1 TLL2 UND VWA4	Homo sapiens (human)
Defective VWF cleavage by ADAMTS13 variant	A disintegrin and metalloproteinase with thrombospondin motifs 13 von Willebrand factor	P04275 Q76LX8	ADAMTS13 C9orf8 F8VWF VWF	Homo sapiens (human)
Enhanced cleavage of VWF variant by ADAMTS13	A disintegrin and metalloproteinase with thrombospondin motifs 13 von Willebrand factor	P04275 Q76LX8	ADAMTS13 C9orf8 F8VWF VWF	Homo sapiens (human)
Platelet Adhesion to exposed collagen	A disintegrin and metalloproteinase with thrombospondin motifs 13 High affinity immunoglobulin epsilon receptor subunit gamma Integrin alpha-10 Integrin alpha-1 Integrin alpha-2 Integrin beta-1 Platelet glycoprotein IX Platelet glycoprotein Ib alpha chain Platelet glycoprotein Ib beta chain Platelet glycoprotein V Platelet glycoprotein VI Tyrosine-protein kinase Fyn Tyrosine-protein kinase Lyn von Willebrand factor	O75578 P04275 P05556 P06241 P07359 P07948 P13224 P14770 P17301 P30273 P40197 P56199 Q76LX8 Q9HCN6	ADAMTS13 C9orf8 CD49B F8VWF FCER1G FNRB FYN GP1BA GP1BB GP5 GP6 GP9 ITGA1 ITGA10 ITGA2 ITGB1 JTK8 LYN MDF2 MSK12 VWF	Homo sapiens (human)
Defective B3GALTL causes PpS	A disintegrin and metalloproteinase with thrombospondin motifs 10 A disintegrin and metalloproteinase with thrombospondin motifs 12 A disintegrin and metalloproteinase with thrombospondin motifs 13 A disintegrin and metalloproteinase with thrombospondin motifs 14 A disintegrin and metalloproteinase with thrombospondin motifs 15 A disintegrin and metalloproteinase with thrombospondin motifs 16 A disintegrin and metalloproteinase with thrombospondin motifs 17 A disintegrin and metalloproteinase with thrombospondin motifs 18 A disintegrin and metalloproteinase with thrombospondin motifs 19 A disintegrin and metalloproteinase with thrombospondin motifs 1 A disintegrin and metalloproteinase with thrombospondin motifs 20 A disintegrin and metalloproteinase with thrombospondin motifs 2 A disintegrin and metalloproteinase with thrombospondin motifs 3 A disintegrin and metalloproteinase with thrombospondin motifs 4 A disintegrin and metalloproteinase with thrombospondin motifs 5 A disintegrin and metalloproteinase with thrombospondin motifs 6 A disintegrin and metalloproteinase with thrombospondin motifs 7 A disintegrin and metalloproteinase with thrombospondin motifs 8 A disintegrin and metalloproteinase with thrombospondin motifs 9 ADAMTS-like protein 1 ADAMTS-like protein 2 ADAMTS-like protein 3 ADAMTS-like protein 4 ADAMTS-like protein 5 Beta-1,3-glucosyltransferase Properdin SCO-spondin Semaphorin-5A Semaphorin-5B Somatomedin-B and thrombospondin type-1 domain-containing protein Spondin-1 Spondin-2 Thrombospondin type-1 domain-containing protein 1 Thrombospondin type-1 domain-containing protein 4 Thrombospondin type-1 domain-containing protein 7A Thrombospondin type-1 domain-containing protein 7B Thrombospondin-1 Thrombospondin-2	A2VEC9 O15072 O75173 O95450 P07996 P27918 P35442 P58397 P59510 P82987 Q13591 Q6UY14 Q6Y288 Q6ZMM2 Q6ZMP0 Q76LX8 Q86TH1 Q8IVN8 Q8N6G6 Q8TE56 Q8TE57 Q8TE58 Q8TE59 Q8TE60 Q8WXS8 Q9BUD6 Q9C0I4 Q9H324 Q9HCB6 Q9NS62 Q9P283 Q9P2N4 Q9UHI8 Q9UKP4 Q9UKP5 Q9UNA0 Q9UP79 Q9UPZ6	ADAMTS1 ADAMTS10 ADAMTS11 ADAMTS12 ADAMTS13 ADAMTS14 ADAMTS15 ADAMTS16 ADAMTS17 ADAMTS18 ADAMTS19 ADAMTS2 ADAMTS20 ADAMTS21 ADAMTS3 ADAMTS4 ADAMTS5 ADAMTS6 ADAMTS7 ADAMTS8 ADAMTS9 ADAMTSL1 ADAMTSL2 ADAMTSL3 ADAMTSL4 ADAMTSL5 ADAMTSR1 ADMP2 B3GALTL B3GLCT B3GTL C8orf84 C9orf8 C9orf94 CFP DIL1 KIAA0366 KIAA0605 KIAA0688 KIAA0762 KIAA0960 KIAA1233 KIAA1312 KIAA1346 KIAA1445 KIAA1679 KIAA2029 KIAA2036 METH1 METH2 PCINP PCPNI PFC RPESP SBSPON SEMA5A SEMA5B SEMAF SEMAG SPON1 SPON2 SSPO SSPOP THBS1 THBS2 THSD1 THSD4 THSD6 THSD7A THSD7B TMTSP TSP TSP1 TSP2 TSRC1 VSGP	Homo sapiens (human)
O-glycosylation of TSR domain-containing proteins	A disintegrin and metalloproteinase with thrombospondin motifs 10 A disintegrin and metalloproteinase with thrombospondin motifs 12 A disintegrin and metalloproteinase with thrombospondin motifs 13 A disintegrin and metalloproteinase with thrombospondin motifs 14 A disintegrin and metalloproteinase with thrombospondin motifs 15 A disintegrin and metalloproteinase with thrombospondin motifs 16 A disintegrin and metalloproteinase with thrombospondin motifs 17 A disintegrin and metalloproteinase with thrombospondin motifs 18 A disintegrin and metalloproteinase with thrombospondin motifs 19 A disintegrin and metalloproteinase with thrombospondin motifs 1 A disintegrin and metalloproteinase with thrombospondin motifs 20 A disintegrin and metalloproteinase with thrombospondin motifs 2 A disintegrin and metalloproteinase with thrombospondin motifs 3 A disintegrin and metalloproteinase with thrombospondin motifs 4 A disintegrin and metalloproteinase with thrombospondin motifs 5 A disintegrin and metalloproteinase with thrombospondin motifs 6 A disintegrin and metalloproteinase with thrombospondin motifs 7 A disintegrin and metalloproteinase with thrombospondin motifs 8 A disintegrin and metalloproteinase with thrombospondin motifs 9 ADAMTS-like protein 1 ADAMTS-like protein 2 ADAMTS-like protein 3 ADAMTS-like protein 4 ADAMTS-like protein 5 Beta-1,3-glucosyltransferase GDP-fucose protein O-fucosyltransferase 2 Properdin SCO-spondin Semaphorin-5A Semaphorin-5B Somatomedin-B and thrombospondin type-1 domain-containing protein Spondin-1 Spondin-2 Thrombospondin type-1 domain-containing protein 1 Thrombospondin type-1 domain-containing protein 4 Thrombospondin type-1 domain-containing protein 7A Thrombospondin type-1 domain-containing protein 7B Thrombospondin-1 Thrombospondin-2	A2VEC9 O15072 O75173 O95450 P07996 P27918 P35442 P58397 P59510 P82987 Q13591 Q6UY14 Q6Y288 Q6ZMM2 Q6ZMP0 Q76LX8 Q86TH1 Q8IVN8 Q8N6G6 Q8TE56 Q8TE57 Q8TE58 Q8TE59 Q8TE60 Q8WXS8 Q9BUD6 Q9C0I4 Q9H324 Q9HCB6 Q9NS62 Q9P283 Q9P2N4 Q9UHI8 Q9UKP4 Q9UKP5 Q9UNA0 Q9UP79 Q9UPZ6 Q9Y2G5	ADAMTS1 ADAMTS10 ADAMTS11 ADAMTS12 ADAMTS13 ADAMTS14 ADAMTS15 ADAMTS16 ADAMTS17 ADAMTS18 ADAMTS19 ADAMTS2 ADAMTS20 ADAMTS21 ADAMTS3 ADAMTS4 ADAMTS5 ADAMTS6 ADAMTS7 ADAMTS8 ADAMTS9 ADAMTSL1 ADAMTSL2 ADAMTSL3 ADAMTSL4 ADAMTSL5 ADAMTSR1 ADMP2 B3GALTL B3GLCT B3GTL C21orf80 C8orf84 C9orf8 C9orf94 CFP DIL1 FUT13 KIAA0366 KIAA0605 KIAA0688 KIAA0762 KIAA0958 KIAA0960 KIAA1233 KIAA1312 KIAA1346 KIAA1445 KIAA1679 KIAA2029 KIAA2036 METH1 METH2 PCINP PCPNI PFC POFUT2 RPESP SBSPON SEMA5A SEMA5B SEMAF SEMAG SPON1 SPON2 SSPO SSPOP THBS1 THBS2 THSD1 THSD4 THSD6 THSD7A THSD7B TMTSP TSP TSP1 TSP2 TSRC1 VSGP	Homo sapiens (human)
Interaction With Cumulus Cells And The Zona Pellucida	Beta-1,4-galactosyltransferase 1 Disintegrin and metalloproteinase domain-containing protein 20 Disintegrin and metalloproteinase domain-containing protein 21 Disintegrin and metalloproteinase domain-containing protein 2 Disintegrin and metalloproteinase domain-containing protein 30 Hyaluronidase PH-20 Oviduct-specific glycoprotein Zona pellucida sperm-binding protein 1 Zona pellucida sperm-binding protein 2 Zona pellucida sperm-binding protein 3 Zona pellucida sperm-binding protein 4	O43506 P15291 P21754 P38567 P60852 Q05996 Q12836 Q12889 Q99965 Q9UKF2 Q9UKJ8	ADAM2 ADAM20 ADAM21 ADAM30 B4GALT1 FTNB GGTB2 HYAL3 MUC9 OGP OVGP1 PH20 SPAM1 ZP1 ZP2 ZP3 ZP3A ZP3B ZP4 ZPA ZPB ZPC	Homo sapiens (human)
Regulation of CDH11 function	Angiopoietin-related protein 4 Cadherin-11 Catenin alpha-1 Catenin beta-1 Catenin delta-1 Disintegrin and metalloproteinase domain-containing protein 19 Disintegrin and metalloproteinase domain-containing protein 33 Junction plakoglobin	O60716 P14923 P35221 P35222 P55287 Q9BY76 Q9BZ11 Q9H013	ADAM19 ADAM33 ANGPTL4 ARP4 C20orf153 CDH11 CTNNA1 CTNNB CTNNB1 CTNND1 CTNNG DP3 HFARP JUP KIAA0384 MLTNB PGAR	Homo sapiens (human)
CD163 mediating an anti-inflammatory response	Disintegrin and metalloproteinase domain-containing protein 17 Furin Inactive rhomboid protein 2 Interleukin-10 Interleukin-6 Mitogen-activated protein kinase 14 Myosin-9 Scavenger receptor cysteine-rich type 1 protein M130 Serine/threonine-protein kinase PLK2	P05231 P09958 P22301 P35579 P78536 Q16539 Q6PJF5 Q86VB7 Q9NYY3	ADAM17 CD163 CSBP CSBP1 CSBP2 CSPB1 CSVP FUR FURIN IFNB2 IL10 IL6 IRHOM2 M130 MAPK14 MXI2 MYH9 PACE PCSK3 PLK2 RHBDF2 RHBDL5 RHBDL6 SAPK2A SNK TACE	Homo sapiens (human)
Release of Hh-Np from the secreting cell	Desert hedgehog protein Disintegrin and metalloproteinase domain-containing protein 17 Glypican-5 Indian hedgehog protein Palmitoleoyl-protein carboxylesterase NOTUM Protein dispatched homolog 2 Signal peptide, CUB and EGF-like domain-containing protein 2 Sonic hedgehog protein	A7MBM2 O43323 P78333 P78536 Q14623 Q15465 Q6P988 Q9NQ36	ADAM17 C15orf36 CEGP1 CSVP DHH DISP2 DISPB GPC5 IHH KIAA1742 LINC00594 NOTUM SCUBE2 SHH TACE	Homo sapiens (human)
TNF signaling	BAG family molecular chaperone regulator 4 Disintegrin and metalloproteinase domain-containing protein 17 Receptor-interacting serine/threonine-protein kinase 1 TNF receptor-associated factor 2 Tumor necrosis factor receptor superfamily member 1A Tumor necrosis factor receptor type 1-associated DEATH domain protein Tumor necrosis factor	O95429 P01375 P19438 P78536 Q12933 Q13546 Q15628	ADAM17 BAG4 CSVP RIP RIP1 RIPK1 SODD TACE TNF TNFA TNFAR TNFR1 TNFRSF1A TNFSF2 TRADD TRAF2 TRAP3	Homo sapiens (human)
Growth hormone receptor signaling	Chorionic somatomammotropin hormone 1 Cytokine-inducible SH2-containing protein Disintegrin and metalloproteinase domain-containing protein 17 Growth hormone receptor Growth hormone variant Insulin receptor substrate 1 Insulin receptor substrate 2 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Prolactin receptor Prolactin Signal transducer and activator of transcription 1-alpha/beta Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Somatotropin Suppressor of cytokine signaling 1 Suppressor of cytokine signaling 2 Suppressor of cytokine signaling 3 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Lyn Tyrosine-protein phosphatase non-receptor type 1 Tyrosine-protein phosphatase non-receptor type 6	O14508 O14543 O15524 O60674 P01236 P01241 P01242 P07948 P0DML2 P10912 P16471 P18031 P27361 P28482 P29350 P35568 P40763 P42224 P42229 P51692 P78536 Q9NSE2 Q9Y4H2	ADAM17 APRF CIS2 CIS3 CISH CSH1 CSVP ERK1 ERK2 G18 GH1 GH2 GHR HCP IRS1 IRS2 JAK2 JTK8 LYN MAPK1 MAPK3 PRKM1 PRKM2 PRKM3 PRL PRLR PTP1B PTP1C PTPN1 PTPN6 SOCS1 SOCS2 SOCS3 SSI1 SSI2 SSI3 STAT1 STAT3 STAT5 STAT5A STAT5B STATI2 TACE TIP3	Homo sapiens (human)
Invadopodia formation	Disintegrin and metalloproteinase domain-containing protein 12 Disintegrin and metalloproteinase domain-containing protein 15 Disintegrin and metalloproteinase domain-containing protein 19 SH3 and PX domain-containing protein 2A	O43184 Q13444 Q5TCZ1 Q9H013	ADAM12 ADAM15 ADAM19 FISH KIAA0418 MDC15 MLTN MLTNB SH3MD1 SH3PXD2A TKS5	Homo sapiens (human)
LGI-ADAM interactions	Disintegrin and metalloproteinase domain-containing protein 11 Disintegrin and metalloproteinase domain-containing protein 22 Disintegrin and metalloproteinase domain-containing protein 23 Disks large homolog 4 Leucine-rich glioma-inactivated protein 1 Leucine-rich repeat LGI family member 2 Leucine-rich repeat LGI family member 3 Leucine-rich repeat LGI family member 4 Syntaxin-1A Syntaxin-1B Voltage-dependent calcium channel gamma-2 subunit Voltage-dependent calcium channel gamma-3 subunit Voltage-dependent calcium channel gamma-4 subunit Voltage-dependent calcium channel gamma-8 subunit	O60359 O75077 O75078 O95970 P61266 P78352 Q16623 Q8N0V4 Q8N135 Q8N145 Q8WXS5 Q9P0K1 Q9UBN1 Q9Y698	ADAM11 ADAM22 ADAM23 CACNG2 CACNG3 CACNG4 CACNG6 CACNG8 DLG4 EPT KIAA1916 LGI1 LGI2 LGI3 LGI4 LGIL2 LGIL3 LGIL4 MDC MDC2 MDC3 PSD95 STX1 STX1A STX1B STX1B1 STX1B2	Homo sapiens (human)
Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant	Delta-like protein 1 Delta-like protein 4 Disintegrin and metalloproteinase domain-containing protein 10 Disintegrin and metalloproteinase domain-containing protein 17 Neurogenic locus notch homolog protein 1 Protein jagged-1 Protein jagged-2	O00548 O14672 P46531 P78504 P78536 Q9NR61 Q9Y219	ADAM10 ADAM17 CSVP DLL1 DLL4 JAG1 JAG2 JAGL1 KUZ MADM NOTCH1 TACE TAN1	Homo sapiens (human)
Constitutive Signaling by NOTCH1 HD Domain Mutants	Delta-like protein 1 Delta-like protein 4 Disintegrin and metalloproteinase domain-containing protein 10 Disintegrin and metalloproteinase domain-containing protein 17 E3 ubiquitin-protein ligase MIB1 E3 ubiquitin-protein ligase MIB2 E3 ubiquitin-protein ligase NEURL1 E3 ubiquitin-protein ligase NEURL1B Neurogenic locus notch homolog protein 1 Polyubiquitin-B Polyubiquitin-C Protein jagged-1 Protein jagged-2 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A8MQ27 O00548 O14672 O76050 P0CG47 P0CG48 P46531 P62979 P62987 P78504 P78536 Q86YT6 Q96AX9 Q9NR61 Q9Y219	ADAM10 ADAM17 CSVP DIP1 DLL1 DLL4 JAG1 JAG2 JAGL1 KIAA1323 KUZ MADM MIB1 MIB2 NEURL NEURL1 NEURL1A NEURL1B NEURL3 NOTCH1 RNF67 RPS27A SKD TACE TAN1 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 ZZANK1 ZZANK2	Homo sapiens (human)
Collagen degradation	5-phosphohydroxy-L-lysine phospho-lyase 72 kDa type IV collagenase Cathepsin B Cathepsin D Cathepsin K Collagen alpha-1(IX) chain Collagen alpha-1(XII) chain Collagen alpha-1(XIII) chain Collagen alpha-1(XIV) chain Collagen alpha-1(XIX) chain Collagen alpha-1(XV) chain Collagen alpha-1(XVI) chain Collagen alpha-1(XVII) chain Collagen alpha-1(XVIII) chain Collagen alpha-1(XXIII) chain Collagen alpha-1(XXV) chain Collagen alpha-1(XXVI) chain Collagen alpha-2(IX) chain Collagen alpha-3(IX) chain Collagenase 3 Disintegrin and metalloproteinase domain-containing protein 10 Disintegrin and metalloproteinase domain-containing protein 17 Disintegrin and metalloproteinase domain-containing protein 9 Furin Interstitial collagenase Macrophage metalloelastase Matrilysin Matrix metalloproteinase-14 Matrix metalloproteinase-15 Matrix metalloproteinase-19 Matrix metalloproteinase-20 Matrix metalloproteinase-9 Neutrophil collagenase Neutrophil elastase Procathepsin L Stromelysin-1 Stromelysin-2 Stromelysin-3 Transmembrane protease serine 6 Trypsin-2	O14672 O60882 P03956 P07339 P07478 P07711 P07858 P08246 P08253 P08254 P09237 P09238 P09958 P14780 P20849 P22894 P24347 P39059 P39060 P39900 P43235 P45452 P50281 P51511 P78536 Q05707 Q07092 Q13443 Q14050 Q14055 Q14993 Q5TAT6 Q86Y22 Q8IU80 Q8IUZ5 Q96A83 Q99542 Q99715 Q9BXS0 Q9UMD9	ADAM10 ADAM17 ADAM9 AGXT2L2 BP180 BPAG2 CLG CLG1 CLG4A CLG4B COL12A1 COL12A1L COL13A1 COL14A1 COL15A1 COL16A1 COL17A1 COL18A1 COL19A1 COL23A1 COL25A1 COL26A1 COL9A1 COL9A2 COL9A3 CPSB CPSD CSVP CTSB CTSD CTSK CTSL CTSL1 CTSO CTSO2 ELA2 ELANE EMID2 EMU2 FUR FURIN HME KIAA0021 KUZ MADM MCMP MDC9 MLTNG MMP1 MMP10 MMP11 MMP12 MMP13 MMP14 MMP15 MMP18 MMP19 MMP2 MMP20 MMP3 MMP7 MMP8 MMP9 MPSL1 PACE PCSK3 PHYKPL PRSS2 PUMP1 RASI STMY1 STMY2 STMY3 TACE TMPRSS6 TRY2 TRYP2 UND	Homo sapiens (human)
Abacavir metabolism	Adenosine deaminase-like protein Alcohol dehydrogenase 1A Cytosolic purine 5'-nucleotidase Phosphoenolpyruvate carboxykinase, cytosolic [GTP]	P07327 P35558 P49902 Q6DHV7	ADAL ADAL1 ADH1 ADH1A NT5B NT5C2 NT5CP PCK1 PEPCK1 PNT5	Homo sapiens (human)
Formation of WDR5-containing histone-modifying complexes	A-kinase anchor protein 8-like Biorientation of chromosomes in cell division protein 1-like 1 Biorientation of chromosomes in cell division protein 1 CXXC-type zinc finger protein 1 Cysteine-rich protein 2-binding protein Histone acetyltransferase KAT2A Histone acetyltransferase KAT2B Histone acetyltransferase KAT8 Histone-lysine N-methyltransferase 2A Histone-lysine N-methyltransferase 2B Histone-lysine N-methyltransferase 2C Histone-lysine N-methyltransferase 2D Histone-lysine N-methyltransferase SETD1A Histone-lysine N-methyltransferase SETD1B Host cell factor 1 Host cell factor 2 KAT8 regulatory NSL complex subunit 1 KAT8 regulatory NSL complex subunit 2 KAT8 regulatory NSL complex subunit 3 Lysine-specific demethylase 6A MAP3K12-binding inhibitory protein 1 Menin Microspherule protein 1 Nuclear receptor coactivator 6 PAX-interacting protein 1 PAXIP1-associated glutamate-rich protein 1 PC4 and SFRS1-interacting protein PHD finger protein 20-like protein 1 PHD finger protein 20 Protein Dr1 Protein dpy-30 homolog Retinoblastoma-binding protein 5 SAGA-associated factor 29 Set1/Ash2 histone methyltransferase complex subunit ASH2 Threonine aspartase 1 Transcriptional adapter 2-alpha Transcriptional adapter 3 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit WD repeat-containing protein 5 WD repeat-containing protein 82 YEATS domain-containing protein 2 ZZ-type zinc finger-containing protein 3	A8MW92 O00255 O14686 O15047 O15294 O15550 O75475 O75478 O75528 P51610 P61964 Q01658 Q03164 Q14686 Q15291 Q6UXN9 Q6ZW49 Q7Z3B3 Q8IYH5 Q8NEZ4 Q8NFC6 Q92830 Q92831 Q96ES7 Q96EZ8 Q96IK1 Q9BTK6 Q9BVI0 Q9C005 Q9H6P5 Q9H7Z6 Q9H8E8 Q9H9L4 Q9NS73 Q9P0U4 Q9P2N6 Q9UBL3 Q9ULM3 Q9ULX6 Q9UMN6 Q9UPS6 Q9Y5Z7	ADA3 AIB3 AKAP8L ALL1 ALR ASH2L ASH2L1 BIG3 BOD1 BOD1L BOD1L1 C12orf41 C16orf53 C20orf104 C20orf13 CCDC101 CENP-36 CFP1 CGBP CSRP2BP CXXC1 CXXC7 DFS70 DPY30 DR1 FAM44A FAM44B GCN5 GCN5L2 GLEA2 HALR HCA58 HCF1 HCFC1 HCFC2 HFC1 HRX HRX2 HTRX INO80Q KANSL1 KANSL2 KANSL3 KAT14 KAT2A KAT2B KAT8 KDM6A KIAA0181 KIAA0304 KIAA0339 KIAA1076 KIAA1197 KIAA1267 KIAA1310 KIAA1327 KIAA1506 KMT2A KMT2B KMT2C KMT2D KMT2F KMT2G LEDGF MBIP MCRS1 MEN1 MLL MLL1 MLL2 MLL3 MLL4 MOF MSL1V1 MSP58 MYST1 NAKAP NAKAP95 NCOA6 NSL1 NSL2 NSL3 NZF OGT PA1 PAGR1 PAXIP1 PAXIP1L PCAF PCCX1 PHF18 PHF20 PHF20L1 PRTD PSIP1 PSIP2 PTIP RAP250 RBBP5 RBQ3 SCG2 SET1 SET1A SET1B SETD1A SETD1B SGF29 SI1 SWD2 TADA2A TADA2L TADA3 TADA3L TASP1 TMEM113 TRBP TRX1 TRX2 TZP UTX WBP7 WDR5 WDR82 WDR82A YEATS2 ZZZ3	Homo sapiens (human)
Defective ADA disrupts (deoxy)adenosine deamination	Adenosine deaminase	P00813	ADA ADA1	Homo sapiens (human)
Ribavirin ADME	Adenosine deaminase Adenosine kinase Cytosolic purine 5'-nucleotidase Equilibrative nucleoside transporter 1 Equilibrative nucleoside transporter 3 Inosine triphosphate pyrophosphatase Nucleoside diphosphate kinase A Nucleoside diphosphate kinase B Purine nucleoside phosphorylase Sodium/nucleoside cotransporter 2 Solute carrier family 28 member 3	O43868 P00491 P00813 P15531 P22392 P49902 P55263 Q99808 Q9BY32 Q9BZD2 Q9HAS3	ADA ADA1 ADK C20orf37 CNT2 CNT3 ENT1 ENT3 ITPA NDPKA NM23 NM23B NME1 NME2 NP NT5B NT5C2 NT5CP PNP PNT5 SLC28A2 SLC28A3 SLC29A1 SLC29A3	Homo sapiens (human)
Purine salvage	AMP deaminase 1 AMP deaminase 2 AMP deaminase 3 Adenine phosphoribosyltransferase Adenosine deaminase-like protein Adenosine deaminase Adenosine kinase Deoxycytidine kinase Deoxyguanosine kinase, mitochondrial GMP reductase 1 GMP reductase 2 Hypoxanthine-guanine phosphoribosyltransferase Purine nucleoside phosphorylase	P00491 P00492 P00813 P07741 P23109 P27707 P36959 P55263 Q01432 Q01433 Q16854 Q6DHV7 Q9P2T1	ADA ADA1 ADAL ADAL1 ADK AMPD1 AMPD2 AMPD3 APRT DCK DGK DGUOK GMPR GMPR1 GMPR2 HPRT HPRT1 NP PNP	Homo sapiens (human)

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