GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **1976 - 2000** of **2090** in total

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Pathway Name ▲	Protein Name	UniProt ID	Gene Symbol	Organism
Truncations of AMER1 destabilize the destruction complex	APC membrane recruitment protein 1 Adenomatous polyposis coli protein Axin-1 Casein kinase I isoform alpha Glycogen synthase kinase-3 beta Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform	O15169 P25054 P30153 P30154 P48729 P49841 P62714 P67775 Q13362 Q14738 Q15172 Q15173 Q16537 Q5JTC6	AMER1 APC AXIN AXIN1 CSNK1A1 DP2.5 FAM123B GSK3B KIAA0044 PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E WTX	Homo sapiens (human)
Tryptophan catabolism	2-amino-3-carboxymuconate-6-semialdehyde decarboxylase 3-hydroxyanthranilate 3,4-dioxygenase Amino acid transporter heavy chain SLC3A2 Indoleamine 2,3-dioxygenase 1 Indoleamine 2,3-dioxygenase 2 Kynureninase Kynurenine 3-monooxygenase Kynurenine formamidase Kynurenine--oxoglutarate transaminase 1 Kynurenine--oxoglutarate transaminase 3 Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial Large neutral amino acids transporter small subunit 1 Neutral amino acid uniporter 4 Tryptophan 2,3-dioxygenase	O15229 P08195 P14902 P46952 P48775 Q01650 Q16719 Q16773 Q63HM1 Q6YBV0 Q6YP21 Q6ZQW0 Q8N5Z0 Q8TDX5	AADAT ACMSD AFMID CCBL1 CCBL2 CD98LC HAAO IDO IDO1 IDO2 INDO INDOL1 KAT2 KAT3 KMO KYAT1 KYAT2 KYAT3 KYNU LAT1 MDU1 MPE16 PAT4 SLC36A4 SLC3A2 SLC7A5 TDO TDO2	Homo sapiens (human)
Type I hemidesmosome assembly	CD151 antigen Collagen alpha-1(XVII) chain Dystonin Integrin alpha-6 Integrin beta-4 Laminin subunit alpha-3 Laminin subunit beta-3 Laminin subunit gamma-2 Plectin	P16144 P23229 P48509 Q03001 Q13751 Q13753 Q15149 Q16787 Q9UMD9	BP180 BP230 BP240 BPAG1 BPAG2 CD151 COL17A1 DMH DST DT ITGA6 ITGB4 KIAA0728 LAMA3 LAMB2T LAMB3 LAMC2 LAMNA LAMNB1 LAMNB2 PLEC PLEC1 TSPAN24	Homo sapiens (human)
Type II Na+/Pi cotransporters	Sodium-dependent phosphate transport protein 2A Sodium-dependent phosphate transport protein 2B Sodium-dependent phosphate transport protein 2C	O95436 Q06495 Q8N130	NPT2 NPT2C NPTIIC SLC17A2 SLC34A1 SLC34A2 SLC34A3	Homo sapiens (human)
Tyrosine catabolism	4-hydroxyphenylpyruvate dioxygenase Fumarylacetoacetase Homogentisate 1,2-dioxygenase Maleylacetoacetate isomerase Tyrosine aminotransferase	O43708 P16930 P17735 P32754 Q93099	FAH GSTZ1 HGD HGO HPD MAAI PPD TAT	Homo sapiens (human)
U12 Dependent Splicing	116 kDa U5 small nuclear ribonucleoprotein component ATP-dependent RNA helicase DDX42 DNA-directed RNA polymerase II subunit RPB11-a DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 General transcription factor IIF subunit 1 General transcription factor IIF subunit 2 Nuclear cap-binding protein subunit 1 Nuclear cap-binding protein subunit 2 Pre-mRNA-processing factor 6 Pre-mRNA-processing-splicing factor 8 Probable ATP-dependent RNA helicase DDX23 Programmed cell death protein 7 RNA-binding region-containing protein 3 Serine/arginine-rich splicing factor 1 Serine/arginine-rich splicing factor 2 Serine/arginine-rich splicing factor 6 Serine/arginine-rich splicing factor 7 Small nuclear ribonucleoprotein E Small nuclear ribonucleoprotein F Small nuclear ribonucleoprotein G Small nuclear ribonucleoprotein Sm D1 Small nuclear ribonucleoprotein Sm D2 Small nuclear ribonucleoprotein Sm D3 Small nuclear ribonucleoprotein-associated proteins B and B' Splicing factor 3B subunit 1 Splicing factor 3B subunit 2 Splicing factor 3B subunit 3 Splicing factor 3B subunit 4 Splicing factor 3B subunit 5 Splicing factor 3B subunit 6 Thioredoxin-like protein 4A U11/U12 small nuclear ribonucleoprotein 25 kDa protein U11/U12 small nuclear ribonucleoprotein 35 kDa protein U11/U12 small nuclear ribonucleoprotein 48 kDa protein U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2 U5 small nuclear ribonucleoprotein 200 kDa helicase U5 small nuclear ribonucleoprotein 40 kDa protein Y-box-binding protein 1 Zinc finger CCHC-type and RNA-binding motif-containing protein 1 Zinc finger matrin-type protein 5	O15514 O75533 O75643 O94906 P13984 P14678 P19387 P19388 P24928 P30876 P35269 P36954 P52298 P52434 P52435 P53803 P61218 P62304 P62306 P62308 P62314 P62316 P62318 P62487 P62875 P67809 P83876 Q01130 Q07955 Q09161 Q13247 Q13435 Q15029 Q15393 Q15427 Q15696 Q16560 Q16629 Q6IEG0 Q6P2Q9 Q86XP3 Q8N8D1 Q8TBF4 Q96DI7 Q96LT9 Q9BUQ8 Q9BV90 Q9BWJ5 Q9UDW3 Q9Y3B4	ASCC3L1 ASF BRR2 C16orf33 C20orf14 C6orf151 CBP20 CBP80 COD DDX23 DDX42 DIM1 EFTUD2 GTF2F1 GTF2F2 HELIC2 HM1 KIAA0017 KIAA0031 KIAA0788 KIAA1839 NCBP NCBP1 NCBP2 NSEP1 PBSCF PBSCG PDCD7 POLR2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J1 POLR2K POLR2L POLRF PRP8BP PRPC8 PRPF6 PRPF8 RAP30 RAP74 RBM40 RNP RNPC3 RPB7 SAP130 SAP14 SAP145 SAP155 SAP49 SF2 SF2P33 SF3B1 SF3B10 SF3B14 SF3B14A SF3B2 SF3B3 SF3B4 SF3B5 SF3B6 SFP38 SFRS1 SFRS2 SFRS6 SFRS7 SNRNP200 SNRNP25 SNRNP35 SNRNP40 SNRNP48 SNRNP65 SNRP116 SNRPB SNRPB1 SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF SNRPG SRP55 SRSF1 SRSF2 SRSF6 SRSF7 TXNL4 TXNL4A U1SNRNPBP U2AF1-RS2 U2AF1L2 U2AF1RS2 URP WDR57 YB1 YBX1 ZCRB1 ZMAT5 ZRSR2	Homo sapiens (human)
UCH proteinases	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Actin, cytoplasmic 1 Actin-like protein 6A Actin-related protein 5 Actin-related protein 8 BRCA1-associated RING domain protein 1 Chromatin-remodeling ATPase INO80 Forkhead box protein K1 Forkhead box protein K2 Histone H2A type 1-A Histone H2A type 1-B/E Histone H2A type 1-C Histone H2A type 1-D Histone H2A type 1-H Histone H2A type 1-J Histone H2A type 1 Histone H2A type 2-A Histone H2A type 2-B Histone H2A type 2-C Histone H2A type 3 Host cell factor 1 INO80 complex subunit B INO80 complex subunit C INO80 complex subunit D INO80 complex subunit E Lysine-specific histone demethylase 2 Methyl-CpG-binding domain protein 5 Methyl-CpG-binding domain protein 6 Microspherule protein 1 Mothers against decapentaplegic homolog 7 NEDD8 Nuclear factor related to kappa-B-binding protein Polycomb group protein ASXL1 Polyubiquitin-B Polyubiquitin-C Proteasomal ubiquitin receptor ADRM1 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Putative Polycomb group protein ASXL2 RuvB-like 1 Sentrin-specific protease 8 TCF3 fusion partner TGF-beta receptor type-1 TGF-beta receptor type-2 Transcriptional repressor protein YY1 Transforming growth factor beta-1 proprotein UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit Ubiquitin carboxyl-terminal hydrolase 15 Ubiquitin carboxyl-terminal hydrolase BAP1 Ubiquitin carboxyl-terminal hydrolase isozyme L1 Ubiquitin carboxyl-terminal hydrolase isozyme L3 Ubiquitin carboxyl-terminal hydrolase isozyme L5 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A5LHX3 O00231 O00232 O00233 O00487 O14818 O15105 O15294 O43242 O75832 O96019 P01137 P04908 P09936 P0C0S8 P0C1Z6 P0CG47 P0CG48 P15374 P17980 P20618 P20671 P25490 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P35998 P36897 P37173 P40306 P43686 P48556 P49720 P49721 P51610 P51665 P55036 P60709 P60896 P60900 P61289 P62191 P62195 P62333 P62979 P62987 P85037 Q01167 Q06323 Q13200 Q14997 Q15008 Q15843 Q16186 Q16401 Q16777 Q53TQ3 Q6FI13 Q6P4R8 Q6PI98 Q76L83 Q7L7L0 Q8IUE6 Q8IXJ9 Q8NB78 Q8NBZ0 Q8TAA3 Q92530 Q92560 Q93077 Q96DN6 Q96EZ8 Q96KK5 Q96LD8 Q96QV6 Q99436 Q99460 Q99728 Q99878 Q9C086 Q9H981 Q9H9F9 Q9P267 Q9UL46 Q9ULG1 Q9UNM6 Q9Y265 Q9Y4E8 Q9Y5K5	ACTB ACTL6A ACTR5 ACTR8 ADRM1 ALK5 AOF1 ARP5 ARP8 ASXH2 ASXL1 ASXL2 BAF53 BAF53A BAP1 BARD1 C18orf37 C6orf193 C7orf76 CCDC95 DEN1 DSS1 FOXK1 FOXK2 GP110 H2AC1 H2AC11 H2AC12 H2AC13 H2AC14 H2AC15 H2AC16 H2AC17 H2AC18 H2AC19 H2AC20 H2AC21 H2AC25 H2AC4 H2AC6 H2AC7 H2AC8 H2AFA H2AFC H2AFD H2AFE H2AFG H2AFI H2AFL H2AFM H2AFN H2AFO H2AFP H2AFQ H2AFR H2AW HC2 HC3 HC8 HC9 HCF1 HCFC1 HFC1 HIST1H2AA HIST1H2AB HIST1H2AC HIST1H2AD HIST1H2AE HIST1H2AG HIST1H2AH HIST1H2AI HIST1H2AJ HIST1H2AK HIST1H2AL HIST1H2AM HIST2H2AA HIST2H2AA3 HIST2H2AA4 HIST2H2AB HIST2H2AC HIST3H2A HMGA1L4 HSPC IFI5111 ILF ILF1 INO80 INO80A INO80B INO80C INO80D INO80E INO80F INO80G INO80H INO80K INO80N INO80Q INO80S INOC1 KDM1B KIAA0072 KIAA0077 KIAA0107 KIAA0272 KIAA0529 KIAA0978 KIAA1259 KIAA1461 KIAA1685 KIAA1887 LMP10 LMP2 LMP7 LMPX LMPY LSD2 MADH7 MADH8 MB1 MBD5 MBD6 MCB1 MCRS1 MECL1 MIP224 MNF MOV34L MSP58 MSS1 NEDD8 NEDP1 NFRKB NMP238 NU OGT PAPA1 PFAAP4 POH1 PROS26 PROS27 PROS30 PRSC2 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 RING10 RING12 RPS27A RUVBL1 SEM1 SENP8 SHFDG1 SHFM1 SKR4 SMAD7 SUG1 SUG2 TBP1 TBP7 TFPT TGFB TGFB1 TGFBR1 TGFBR2 TIP49 TIP49A TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 UCH37 UCHL1 UCHL3 UCHL5 USP15 X Y Y2 YY1 Z ZNHIT4	Homo sapiens (human)
UNC93B1 deficiency - HSE	Protein unc-93 homolog B1 Toll-like receptor 3	O15455 Q9H1C4	TLR3 UNC93 UNC93B UNC93B1	Homo sapiens (human)
Ub-specific processing proteases	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Androgen receptor Antiviral innate immune response receptor RIG-I Ataxin-7 Axin-1 Axin-2 Baculoviral IAP repeat-containing protein 2 Baculoviral IAP repeat-containing protein 3 Beclin-1 Beta-2 adrenergic receptor Beta-arrestin-1 Beta-arrestin-2 CAAX prenyl protease 2 Cell division cycle protein 20 homolog Cellular tumor antigen p53 Centriolar coiled-coil protein of 110 kDa Claspin Cyclin-A1 Cyclin-A2 Cystic fibrosis transmembrane conductance regulator DNA damage-binding protein 2 DNA polymerase beta E3 ubiquitin-protein ligase Mdm2 E3 ubiquitin-protein ligase RNF123 E3 ubiquitin-protein ligase RNF128 E3 ubiquitin-protein ligase RNF146 E3 ubiquitin-protein ligase SIAH2 E3 ubiquitin-protein ligase SMURF2 Forkhead box protein O4 Hepatocyte growth factor-regulated tyrosine kinase substrate Histone H2A type 1-A Histone H2A type 1-B/E Histone H2A type 1-C Histone H2A type 1-D Histone H2A type 1-H Histone H2A type 1-J Histone H2A type 1 Histone H2A type 2-A Histone H2A type 2-B Histone H2A type 2-C Histone H2A type 3 Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/F/G/I Histone H2B type 1-D Histone H2B type 1-H Histone H2B type 1-J Histone H2B type 1-K Histone H2B type 1-L Histone H2B type 1-M Histone H2B type 1-N Histone H2B type 1-O Histone H2B type 2-E Histone H2B type 2-F Histone H2B type 3-B Histone acetyltransferase KAT2A Hypoxia-inducible factor 1-alpha Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 4 Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 8 Insulin-degrading enzyme Interferon-induced helicase C domain-containing protein 1 Interleukin-33 Kelch-like ECH-associated protein 1 M-phase inducer phosphatase 1 Methionine adenosyltransferase 2 subunit beta Mitochondrial Rho GTPase 1 Mitochondrial import receptor subunit TOM20 homolog Mitochondrial import receptor subunit TOM70 Mitochondrial ubiquitin ligase activator of NFKB 1 Mitogen-activated protein kinase kinase kinase 7 Mothers against decapentaplegic homolog 1 Mothers against decapentaplegic homolog 2 Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 4 Mothers against decapentaplegic homolog 7 Myc proto-oncogene protein NF-kappa-B essential modulator NF-kappa-B inhibitor alpha Peptidyl-prolyl cis-trans isomerase FKBP8 Peptidyl-tRNA hydrolase 2, mitochondrial Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN Poly [ADP-ribose] polymerase tankyrase-1 Poly [ADP-ribose] polymerase tankyrase-2 Polyubiquitin-B Polyubiquitin-C Proteasomal ubiquitin receptor ADRM1 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Protein Mdm4 Receptor-interacting serine/threonine-protein kinase 1 RuvB-like 1 S-phase kinase-associated protein 2 Signal transducing adapter molecule 2 Sin3 histone deacetylase corepressor complex component SDS3 Sorting nexin-3 TGF-beta receptor type-1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 TNF receptor-associated factor 2 TNF receptor-associated factor 6 Trans-acting T-cell-specific transcription factor GATA-3 Transcription initiation factor TFIID subunit 10 Transcription initiation factor TFIID subunit 9B Transcriptional adapter 2-beta Transcriptional adapter 3 Transformation/transcription domain-associated protein Ubiquitin carboxyl-terminal hydrolase 10 Ubiquitin carboxyl-terminal hydrolase 11 Ubiquitin carboxyl-terminal hydrolase 12 Ubiquitin carboxyl-terminal hydrolase 13 Ubiquitin carboxyl-terminal hydrolase 14 Ubiquitin carboxyl-terminal hydrolase 15 Ubiquitin carboxyl-terminal hydrolase 16 Ubiquitin carboxyl-terminal hydrolase 17-like protein 10 Ubiquitin carboxyl-terminal hydrolase 17-like protein 11 Ubiquitin carboxyl-terminal hydrolase 17-like protein 12 Ubiquitin carboxyl-terminal hydrolase 17-like protein 13 Ubiquitin carboxyl-terminal hydrolase 17-like protein 15 Ubiquitin carboxyl-terminal hydrolase 17-like protein 17 Ubiquitin carboxyl-terminal hydrolase 17-like protein 18 Ubiquitin carboxyl-terminal hydrolase 17-like protein 19 Ubiquitin carboxyl-terminal hydrolase 17-like protein 1 Ubiquitin carboxyl-terminal hydrolase 17-like protein 20 Ubiquitin carboxyl-terminal hydrolase 17-like protein 21 Ubiquitin carboxyl-terminal hydrolase 17-like protein 22 Ubiquitin carboxyl-terminal hydrolase 17-like protein 24 Ubiquitin carboxyl-terminal hydrolase 17-like protein 3 Ubiquitin carboxyl-terminal hydrolase 17-like protein 5 Ubiquitin carboxyl-terminal hydrolase 17 Ubiquitin carboxyl-terminal hydrolase 19 Ubiquitin carboxyl-terminal hydrolase 20 Ubiquitin carboxyl-terminal hydrolase 21 Ubiquitin carboxyl-terminal hydrolase 22 Ubiquitin carboxyl-terminal hydrolase 24 Ubiquitin carboxyl-terminal hydrolase 25 Ubiquitin carboxyl-terminal hydrolase 26 Ubiquitin carboxyl-terminal hydrolase 28 Ubiquitin carboxyl-terminal hydrolase 2 Ubiquitin carboxyl-terminal hydrolase 30 Ubiquitin carboxyl-terminal hydrolase 33 Ubiquitin carboxyl-terminal hydrolase 34 Ubiquitin carboxyl-terminal hydrolase 37 Ubiquitin carboxyl-terminal hydrolase 3 Ubiquitin carboxyl-terminal hydrolase 42 Ubiquitin carboxyl-terminal hydrolase 44 Ubiquitin carboxyl-terminal hydrolase 47 Ubiquitin carboxyl-terminal hydrolase 48 Ubiquitin carboxyl-terminal hydrolase 49 Ubiquitin carboxyl-terminal hydrolase 4 Ubiquitin carboxyl-terminal hydrolase 5 Ubiquitin carboxyl-terminal hydrolase 7 Ubiquitin carboxyl-terminal hydrolase 8 Ubiquitin carboxyl-terminal hydrolase 9X Ubiquitin carboxyl-terminal hydrolase CYLD Ubiquitin recognition factor in ER-associated degradation protein 1 Ubiquitin thioesterase OTUB1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Ubl carboxyl-terminal hydrolase 18 Voltage-dependent anion-selective channel protein 1 Voltage-dependent anion-selective channel protein 2 Voltage-dependent anion-selective channel protein 3 WD repeat-containing protein 20 WD repeat-containing protein 48	A5LHX3 A6NCW0 A6NCW7 A8MUK1 C9J2P7 C9JJH3 C9JLJ4 C9JPN9 C9JVI0 D6R901 D6R9N7 D6RA61 D6RBQ6 D6RCP7 D6RJB6 O00231 O00232 O00233 O00487 O14818 O14964 O15105 O15151 O15169 O15265 O43242 O43255 O43303 O43318 O60493 O60814 O75317 O75528 O75604 O75832 O75886 O94826 O94966 O95271 O95760 O95786 P01106 P04637 P04908 P06746 P06899 P07550 P0C0S8 P0C7I0 P0CG47 P0CG48 P10275 P13569 P14735 P17980 P20248 P20618 P20671 P21796 P23527 P23771 P25786 P25787 P25788 P25789 P25963 P28062 P28065 P28066 P28070 P28072 P28074 P30304 P32121 P33778 P35998 P36897 P40306 P40818 P43686 P45880 P45974 P48556 P49407 P49720 P49721 P51665 P51784 P54578 P55036 P58876 P60484 P60896 P60900 P61289 P62191 P62195 P62333 P62807 P62979 P62987 P78396 P84022 P98177 Q00987 Q06323 Q0WX57 Q12834 Q12933 Q12962 Q13107 Q13200 Q13309 Q13485 Q13489 Q13490 Q13546 Q14145 Q14318 Q14457 Q14694 Q14997 Q15008 Q15388 Q15750 Q15796 Q15797 Q16186 Q16401 Q16665 Q16777 Q16778 Q5QNW6 Q5XPI4 Q6FI13 Q6R6M4 Q70CQ1 Q70CQ2 Q70CQ3 Q7L7L0 Q7RTZ2 Q86T82 Q86TJ2 Q86UV5 Q8IUE6 Q8IXI2 Q8N257 Q8TAA3 Q8TAF3 Q8TBZ3 Q8TEB7 Q8TEY7 Q92466 Q92530 Q92830 Q92890 Q92995 Q93008 Q93009 Q93077 Q93079 Q969V5 Q96A08 Q96FW1 Q96K76 Q96KK5 Q96QV6 Q96RU2 Q99436 Q99460 Q99877 Q99878 Q99879 Q99880 Q9BXU7 Q9BYX4 Q9H0E7 Q9H2K2 Q9H7L9 Q9H9J4 Q9HAU4 Q9HAW4 Q9HBM6 Q9NQC7 Q9NTX7 Q9NZL9 Q9UHP3 Q9UK80 Q9UL46 Q9UMW8 Q9UNM6 Q9UPT9 Q9UPU5 Q9Y256 Q9Y265 Q9Y277 Q9Y2K6 Q9Y2T1 Q9Y3E5 Q9Y4A5 Q9Y4E8 Q9Y4K3 Q9Y5T5 Q9Y6I4 Q9Y6K9	ABCC7 ADA2B ADA3 ADRB2 ADRB2R ADRM1 AFX AFX1 ALK5 API1 API2 AR ARB2 ARHT1 ARR1 ARR2 ARRB1 ARRB2 ATXN7 AXIN AXIN1 AXIN2 B2AR BECN1 BHLHE39 BHLHE78 BIRC2 BIRC3 BIT1 BSP1 C1orf166 C7orf76 C9orf26 CCN1 CCNA CCNA1 CCNA2 CCP110 CDC20 CDC25A CEP110 CFTR CLSPN CP110 CYLD CYLD1 DDB2 DDX58 DFFRX DHTR DPC4 DSS1 DUB3 FACE2 FAM FBXL1 FIP3 FKBP38 FKBP8 FOXO4 GATA3 GCN5 GCN5L2 GIDE GP110 GT197 H2AC1 H2AC11 H2AC12 H2AC13 H2AC14 H2AC15 H2AC16 H2AC17 H2AC18 H2AC19 H2AC20 H2AC21 H2AC25 H2AC4 H2AC6 H2AC7 H2AC8 H2AFA H2AFC H2AFD H2AFE H2AFG H2AFI H2AFL H2AFM H2AFN H2AFO H2AFP H2AFQ H2AFR H2AW H2BC1 H2BC10 H2BC11 H2BC12 H2BC13 H2BC14 H2BC15 H2BC17 H2BC18 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H2BFA H2BFB H2BFC H2BFD H2BFE H2BFF H2BFG H2BFH H2BFJ H2BFK H2BFL H2BFN H2BFQ H2BFR H2BFT H2BU1 HAUSP HBP HC2 HC3 HC8 HC9 HGS HIF1A HIRIP1 HIRIP2 HIST1H2AA HIST1H2AB HIST1H2AC HIST1H2AD HIST1H2AE HIST1H2AG HIST1H2AH HIST1H2AI HIST1H2AJ HIST1H2AK HIST1H2AL HIST1H2AM HIST1H2BA HIST1H2BB HIST1H2BC HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2BI HIST1H2BJ HIST1H2BK HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST2H2AA HIST2H2AA3 HIST2H2AA4 HIST2H2AB HIST2H2AC HIST2H2BE HIST2H2BF HIST3H2A HIST3H2BB HRS HSPC IDE IFI5111 IFIH1 IKBA IKBKG IL1F11 IL33 INO80H INRF2 ISG43 ISOT ISOT3 KAT2A KEAP1 KIAA0016 KIAA0055 KIAA0072 KIAA0077 KIAA0107 KIAA0132 KIAA0190 KIAA0419 KIAA0529 KIAA0570 KIAA0719 KIAA0729 KIAA0849 KIAA0891 KIAA1003 KIAA1057 KIAA1063 KIAA1097 KIAA1449 KIAA1515 KIAA1594 KLHL19 KPC1 LMP10 LMP2 LMP7 LMPX LMPY LSFR3A MAD3 MADH1 MADH2 MADH3 MADH4 MADH7 MADH8 MADR1 MADR2 MAP3K7 MAP3K7IP1 MAPL MAT2B MB1 MCB1 MDA5 MDM2 MDM4 MDMX MECL1 MIHB MIHC MIP224 MLLT7 MMAC1 MOP1 MOV34L MSS1 MUL1 MULAN MYC NEMO NFHEV NFKBI NFKBIA NMP238 NR3C4 NU OTB1 OTU1 OTUB1 P53 PAF400 PARP5A PARP5B PARPL PASD8 PFAAP4 POH1 POLB PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 PTEN PTH2 PTRH2 RCE1 RCE1A RCE1B RH116 RHOT1 RIGI RING10 RING12 RIP RIP1 RIPK1 RNF123 RNF128 RNF146 RNF218 RNF48 RNF49 RNF85 RPS27A RUVBL1 SAP45 SCA7 SDS3 SEM1 SHFDG1 SHFM1 SIAH2 SKP2 SKR4 SMAD1 SMAD2 SMAD3 SMAD4 SMAD7 SMURF2 SNX3 STAM2 SUDS3 SUG1 SUG2 TAB1 TADA2B TADA3 TADA3L TAF10 TAF2A TAF2H TAF9B TAF9L TAFII30 TAK1 TANK2 TBP1 TBP7 TEP1 TGFBR1 TGR TGT TIN1 TINF1 TIP49 TIP49A TNKL TNKS TNKS1 TNKS2 TOM70 TOMM20 TOMM70 TOMM70A TP53 TRAF2 TRAF6 TRAP2 TRAP3 TRRAP TSH2B UAF1 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 UBH1 UBP41 UBPY UFD1 UFD1L UHX1 UNP UNPH USP10 USP11 USP12 USP12L1 USP13 USP14 USP15 USP16 USP17 USP17B USP17F USP17H USP17I USP17J USP17K USP17L USP17L1 USP17L10 USP17L11 USP17L12 USP17L13 USP17L15 USP17L17 USP17L18 USP17L19 USP17L1P USP17L2 USP17L20 USP17L21 USP17L22 USP17L24 USP17L25 USP17L26 USP17L27 USP17L28 USP17L29 USP17L3 USP17L30 USP17L4 USP17L5 USP17L8 USP17M USP18 USP19 USP2 USP20 USP21 USP22 USP23 USP24 USP25 USP26 USP28 USP3 USP30 USP31 USP33 USP34 USP37 USP3L USP4 USP42 USP44 USP47 USP48 USP49 USP5 USP7 USP8 USP9 USP9X VDAC VDAC1 VDAC2 VDAC3 VDU1 VDU2 WDR20 WDR48 X Y Y2 Z ZMYND9	Homo sapiens (human)
Ubiquinol biosynthesis	2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial 4-hydroxybenzoate polyprenyltransferase, mitochondrial 5-demethoxyubiquinone hydroxylase, mitochondrial All trans-polyprenyl-diphosphate synthase PDSS1 All trans-polyprenyl-diphosphate synthase PDSS2 Atypical kinase COQ8A, mitochondrial Atypical kinase COQ8B, mitochondrial Ubiquinone biosynthesis O-methyltransferase, mitochondrial Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial Ubiquinone biosynthesis protein COQ9, mitochondrial	O75208 Q5HYK3 Q5T2R2 Q86YH6 Q8NI60 Q96D53 Q96H96 Q99807 Q9NZJ6 Q9Y2Z9 Q9Y3A0	ADCK3 ADCK4 C16orf49 C6orf210 CABC1 CL640 COQ2 COQ3 COQ4 COQ5 COQ6 COQ7 COQ8A COQ8B COQ9 DLP1 DPS1 PDSS1 PDSS2 TPRT	Homo sapiens (human)
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 M-phase inducer phosphatase 1 Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Serine/threonine-protein kinase Chk1 Serine/threonine-protein kinase Chk2 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A5LHX3 O00231 O00232 O00233 O00487 O14757 O14818 O43242 O75832 O96017 P0CG47 P0CG48 P17980 P20618 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P30304 P35998 P40306 P43686 P48556 P49720 P49721 P51665 P55036 P60896 P60900 P61289 P62191 P62195 P62333 P62979 P62987 Q06323 Q13200 Q14997 Q15008 Q16401 Q8TAA3 Q92530 Q99436 Q99460 Q9UL46 Q9UNM6	C7orf76 CDC25A CDS1 CHEK1 CHEK2 CHK1 CHK2 DSS1 HC2 HC3 HC8 HC9 HSPC IFI5111 KIAA0072 KIAA0077 KIAA0107 LMP10 LMP2 LMP7 LMPX LMPY MB1 MCB1 MECL1 MIP224 MOV34L MSS1 NU PFAAP4 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 RAD53 RING10 RING12 RPS27A SEM1 SHFDG1 SHFM1 SUG1 SUG2 TBP1 TBP7 TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 X Y Y2 Z	Homo sapiens (human)
Ubiquitin-dependent degradation of Cyclin D	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Cyclin-dependent kinase 4 G1/S-specific cyclin-D1 Glycogen synthase kinase-3 beta Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A5LHX3 O00231 O00232 O00233 O00487 O14818 O43242 O75832 P0CG47 P0CG48 P11802 P17980 P20618 P24385 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P35998 P40306 P43686 P48556 P49720 P49721 P49841 P51665 P55036 P60896 P60900 P61289 P62191 P62195 P62333 P62979 P62987 Q06323 Q13200 Q14997 Q15008 Q16401 Q8TAA3 Q92530 Q99436 Q99460 Q9UL46 Q9UNM6	BCL1 C7orf76 CCND1 CDK4 DSS1 GSK3B HC2 HC3 HC8 HC9 HSPC IFI5111 KIAA0072 KIAA0077 KIAA0107 LMP10 LMP2 LMP7 LMPX LMPY MB1 MCB1 MECL1 MIP224 MOV34L MSS1 NU PFAAP4 POH1 PRAD1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 RING10 RING12 RPS27A SEM1 SHFDG1 SHFM1 SUG1 SUG2 TBP1 TBP7 TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 X Y Y2 Z	Homo sapiens (human)
Unblocking of NMDA receptors, glutamate binding and activation	Alpha-actinin-2 Calcium/calmodulin-dependent protein kinase type II subunit alpha Calcium/calmodulin-dependent protein kinase type II subunit beta Calcium/calmodulin-dependent protein kinase type II subunit delta Calcium/calmodulin-dependent protein kinase type II subunit gamma Calmodulin-1 Disks large homolog 1 Disks large homolog 2 Disks large homolog 3 Disks large homolog 4 Glutamate receptor 1 Glutamate receptor 2 Glutamate receptor 3 Glutamate receptor 4 Glutamate receptor ionotropic, NMDA 1 Glutamate receptor ionotropic, NMDA 2A Glutamate receptor ionotropic, NMDA 2B Glutamate receptor ionotropic, NMDA 2C Glutamate receptor ionotropic, NMDA 2D Leucine-rich repeat-containing protein 7 Neurofilament light polypeptide	O15399 P07196 P0DP23 P35609 P42261 P42262 P42263 P48058 P78352 Q05586 Q12879 Q12959 Q13224 Q13554 Q13555 Q13557 Q14957 Q15700 Q92796 Q96NW7 Q9UQM7	ACTN2 CALM CALM1 CAM CAM1 CAM2 CAMK CAMK-II CAMK2 CAMK2A CAMK2B CAMK2D CAMK2G CAMKA CAMKB CAMKD CAMKG DLG1 DLG2 DLG3 DLG4 GLUA1 GLUH1 GLUR1 GLUR2 GLUR3 GLUR4 GLURC GRIA1 GRIA2 GRIA3 GRIA4 GRIN1 GRIN2A GRIN2B GRIN2C GRIN2D GluA2 GluA3 GluA4 GluN2D KIAA0968 KIAA1232 KIAA1365 LAP1 LRRC7 NEFL NF68 NFL NMDAR1 NMDAR2A NMDAR2B NMDAR2C NMDAR2D PSD95	Homo sapiens (human)
Uncoating of the HIV Virion	Gag polyprotein Gag-Pol polyprotein Peptidyl-prolyl cis-trans isomerase A Protein Nef Protein Rev Protein Vpr Protein Vpu Virion infectivity factor	P04585 P04591 P04601 P04618 P05919 P62937 P69723 P69726	CYPA PPIA gag gag-pol nef rev vif vpr vpu	Homo sapiens (human)
Uncoating of the Influenza Virion	Hemagglutinin Matrix protein 1 Matrix protein 2 Neuraminidase Nuclear export protein Nucleoprotein Polymerase acidic protein Polymerase basic protein 2 RNA-directed RNA polymerase catalytic subunit	P03428 P03431 P03433 P03452 P03466 P03468 P03485 P03508 P06821	HA M NA NP NS PA PB1 PB2	Homo sapiens (human)
Unwinding of DNA	Cell division control protein 45 homolog DNA helicase MCM8 DNA replication complex GINS protein PSF1 DNA replication complex GINS protein PSF2 DNA replication complex GINS protein PSF3 DNA replication complex GINS protein SLD5 DNA replication licensing factor MCM2 DNA replication licensing factor MCM3 DNA replication licensing factor MCM4 DNA replication licensing factor MCM5 DNA replication licensing factor MCM6 DNA replication licensing factor MCM7	O75419 P25205 P33991 P33992 P33993 P49736 Q14566 Q14691 Q9BRT9 Q9BRX5 Q9UJA3 Q9Y248	BM28 C20orf154 CCNL1 CDC21 CDC45 CDC45L CDC45L2 CDC46 CDC47 CDCL1 GINS1 GINS2 GINS3 GINS4 KIAA0030 KIAA0186 MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 MCM8 PSF1 PSF2 PSF3 SLD5	Homo sapiens (human)
Uptake and function of anthrax toxins	Calmodulin-1 Calmodulin-sensitive adenylate cyclase Dual specificity mitogen-activated protein kinase kinase 1 Dual specificity mitogen-activated protein kinase kinase 2 Dual specificity mitogen-activated protein kinase kinase 4 Dual specificity mitogen-activated protein kinase kinase 7 Furin Lethal factor Programmed cell death 6-interacting protein Protective antigen	O14733 P09958 P0DP23 P13423 P15917 P36507 P40136 P45985 Q02750 Q8WUM4	AIP1 ALIX CALM CALM1 CAM CAM1 FUR FURIN JNKK1 JNKK2 KIAA1375 MAP2K1 MAP2K2 MAP2K4 MAP2K7 MEK1 MEK2 MEK4 MEK7 MKK2 MKK4 MKK7 PACE PCSK3 PDCD6IP PRKMK1 PRKMK2 PRKMK4 PRKMK7 SEK1 SERK1 SKK1 SKK4 cya lef pag pagA	Homo sapiens (human)
Uptake and function of diphtheria toxin	CD9 antigen Diphtheria toxin Elongation factor 2 Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Proheparin-binding EGF-like growth factor Thioredoxin reductase 1, cytoplasmic	P00588 P07900 P08238 P13639 P21926 Q16881 Q99075	CD9 DTR DTS EEF2 EF2 GRIM12 HBEGF HEGFL HSP90A HSP90AA1 HSP90AB1 HSP90B HSPC1 HSPC2 HSPC3 HSPCA HSPCB KDRF MIC3 TSPAN29 TXNRD1	Homo sapiens (human)
Uptake of dietary cobalamins into enterocytes	Chymotrypsinogen B2 Chymotrypsinogen B Cobalamin binding intrinsic factor Cubilin Lysosomal cobalamin transport escort protein LMBD1 Lysosomal cobalamin transporter ABCD4 Protein amnionless Serine protease 1 Transcobalamin-1 Trypsin-3	O14678 O60494 P07477 P17538 P20061 P27352 P35030 Q6GPI1 Q9BXJ7 Q9NUN5	ABCD4 AMN C6orf209 CBLIF CTRB CTRB1 CTRB2 CUBN GIF IFCR IFMH LMBRD1 NESI PRSS1 PRSS3 PRSS4 PXMP1L TC1 TCN1 TRP1 TRY1 TRY3 TRY4 TRYP1	Homo sapiens (human)
Urea cycle	Arginase-1 Arginase-2, mitochondrial Argininosuccinate lyase Argininosuccinate synthase Carbamoyl-phosphate synthase [ammonia], mitochondrial Mitochondrial ornithine transporter 1 Mitochondrial ornithine transporter 2 N-acetylglutamate synthase, mitochondrial NmrA-like family domain-containing protein 1 Ornithine transcarbamylase, mitochondrial	P00480 P00966 P04424 P05089 P31327 P78540 Q8N159 Q9BXI2 Q9HBL8 Q9Y619	ARG1 ARG2 ASL ASS ASS1 CPS1 HSCARG NAGS NMRAL1 ORC1 ORC2 ORNT1 ORNT2 OTC SLC25A15 SLC25A2	Homo sapiens (human)
VEGF binds to VEGFR leading to receptor dimerization	Placenta growth factor Vascular endothelial growth factor A, long form Vascular endothelial growth factor B Vascular endothelial growth factor C Vascular endothelial growth factor D Vascular endothelial growth factor receptor 1 Vascular endothelial growth factor receptor 2 Vascular endothelial growth factor receptor 3	O43915 P15692 P17948 P35916 P35968 P49763 P49765 P49767	FIGF FLK1 FLT FLT1 FLT4 FRT KDR PGF PGFL PLGF VEGF VEGFA VEGFB VEGFC VEGFD VEGFR1 VEGFR2 VEGFR3 VRF	Homo sapiens (human)
VEGF ligand-receptor interactions	Placenta growth factor Vascular endothelial growth factor A, long form Vascular endothelial growth factor B Vascular endothelial growth factor C Vascular endothelial growth factor D	O43915 P15692 P49763 P49765 P49767	FIGF PGF PGFL PLGF VEGF VEGFA VEGFB VEGFC VEGFD VRF	Homo sapiens (human)
VEGFA-VEGFR2 Pathway	Abl interactor 1 Abl interactor 2 Actin-binding protein WASF1 Actin-binding protein WASF2 Actin-binding protein WASF3 Adapter molecule crk BAR/IMD domain-containing adapter protein 2 Breast cancer anti-estrogen resistance protein 1 Cell division control protein 42 homolog Cytochrome b-245 heavy chain Cytochrome b-245 light chain Cytoplasmic FMR1-interacting protein 1 Cytoplasmic FMR1-interacting protein 2 Cytoplasmic protein NCK2 Dedicator of cytokinesis protein 1 Engulfment and cell motility protein 1 Engulfment and cell motility protein 2 Focal adhesion kinase 1 Guanine nucleotide exchange factor VAV2 Guanine nucleotide exchange factor VAV3 Heat shock protein HSP 90-alpha Heat shock protein beta-1 Integrin alpha-V Integrin beta-3 MAP kinase-activated protein kinase 2 MAP kinase-activated protein kinase 3 Mitogen-activated protein kinase 11 Mitogen-activated protein kinase 12 Mitogen-activated protein kinase 13 Mitogen-activated protein kinase 14 Nck-associated protein 1-like Nck-associated protein 1 Neutrophil cytosol factor 1 Neutrophil cytosol factor 2 Neutrophil cytosol factor 4 Paxillin Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Protein BRICK1 Protein-tyrosine kinase 2-beta Proto-oncogene vav Ras-related C3 botulinum toxin substrate 1 Rho-associated protein kinase 1 Rho-associated protein kinase 2 SH2 domain-containing adapter protein B SH2 domain-containing protein 2A SH2/SH3 adapter protein NCK1 SHC-transforming protein 2 Serine/threonine-protein kinase PAK 2 Transforming protein RhoA Tyrosine-protein kinase Fyn Tyrosine-protein kinase receptor UFO Vascular endothelial growth factor receptor 2 cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit gamma	O00459 O15264 O43639 O75116 P04792 P04839 P05106 P06241 P06756 P07900 P13498 P14598 P15498 P16333 P17612 P19878 P22612 P22694 P27986 P30530 P35968 P42336 P42338 P46108 P49023 P49137 P52735 P53778 P55160 P56945 P60953 P61586 P63000 P98077 Q05397 Q13177 Q13464 Q14185 Q14289 Q15080 Q15464 Q15759 Q16539 Q16644 Q7L576 Q8IZP0 Q8WUW1 Q92556 Q92558 Q96F07 Q96JJ3 Q9NP31 Q9NYB9 Q9UKW4 Q9UPY6 Q9UQB8 Q9Y2A7 Q9Y6W5	ABI1 ABI2 ARGBPIA ARH12 ARHA AXL BAIAP2 BCAR1 BRK1 C3orf10 CAS CASS1 CDC42 CED12A CRK CRKAS CSBP CSBP1 CSBP2 CSPB1 CYBA CYBB CYFIP1 CYFIP2 DOCK1 ELMO1 ELMO2 ERK6 FAK FAK1 FAK2 FLK1 FYN GP3A GRB1 GRB4 HEM1 HEM2 HSP27 HSP28 HSP90A HSP90AA1 HSPB1 HSPC1 HSPCA ITGAV ITGB3 KDR KIAA0068 KIAA0269 KIAA0281 KIAA0587 KIAA0619 KIAA0900 KIAA1168 KIAA1834 MAPK11 MAPK12 MAPK13 MAPK14 MAPKAPK2 MAPKAPK3 MSK8 MXI2 NAP1 NCF1 NCF2 NCF4 NCK NCK1 NCK2 NCKAP1 NCKAP1L NOX2 NOXA2 NOXO2 P67PHOX PAK2 PIK3C1 PIK3CA PIK3CB PIK3R1 PIK3R2 PIR121 PKACA PRKACA PRKACB PRKACG PRKM11 PRKM13 PTK2 PTK2B PXN PYK2 RAC1 RAFTK RHO12 RHOA ROCK1 ROCK2 SAPK2 SAPK2A SAPK2B SAPK3 SAPK4 SCAP SCAR1 SCAR3 SCK SH2D2A SH3PXD1A SH3PXD4 SHB SHC2 SHCB SSH3BP1 TC25 TSAD UFO VAV VAV1 VAV2 VAV3 VEGFR2 VNRA VRAP VTNR WASF1 WASF2 WASF3 WAVE1 WAVE2 WAVE3	Homo sapiens (human)
VEGFR2 mediated cell proliferation	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 3-phosphoinositide-dependent protein kinase 1 Calmodulin-1 GTPase HRas GTPase NRas Inositol 1,4,5-trisphosphate receptor type 2 Inositol 1,4,5-trisphosphate receptor type 3 Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1 Protein kinase C alpha type Protein kinase C beta type Protein kinase C delta type Protein kinase C zeta type Ras GTPase-activating protein 1 S-adenosylhomocysteine hydrolase-like protein 1 Sphingosine kinase 1 Vascular endothelial growth factor receptor 2	O15530 O43865 P01111 P01112 P05771 P0DP23 P17252 P19174 P20936 P35968 Q05513 Q05655 Q14571 Q14573 Q14643 Q9NYA1	AHCYL1 CALM CALM1 CAM CAM1 DCAL FLK1 GAP HRAS HRAS1 INSP3R1 IRBIT ITPR1 ITPR2 ITPR3 KDR NRAS PDK1 PDPK1 PKC2 PKCA PKCB PKCD PLC1 PLCG1 PRKACA PRKCA PRKCB PRKCB1 PRKCD PRKCZ RASA RASA1 SK1 SPHK SPHK1 SPK VEGFR2 XPVKONA	Homo sapiens (human)
VEGFR2 mediated vascular permeability	3-phosphoinositide-dependent protein kinase 1 Acyl-coenzyme A thioesterase THEM4 Cadherin-5 Calmodulin-1 Catenin alpha-1 Catenin beta-1 Catenin delta-1 Caveolin-1 Guanine nucleotide exchange factor VAV2 Guanine nucleotide exchange factor VAV3 Heat shock protein HSP 90-alpha Junction plakoglobin Membrane protein Nitric oxide synthase 3 Nucleoprotein Proline-rich protein 5 Proto-oncogene vav RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Rapamycin-insensitive companion of mTOR Ras-related C3 botulinum toxin substrate 1 Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 2 Serine/threonine-protein kinase PAK 3 Serine/threonine-protein kinase mTOR Target of rapamycin complex 2 subunit MAPKAP1 Target of rapamycin complex subunit LST8 Tribbles homolog 3	O15530 O60716 O75914 P07900 P0DP23 P0DTC5 P0DTC9 P14923 P15498 P29474 P31749 P31751 P33151 P35221 P35222 P42345 P52735 P63000 P85299 Q03135 Q13153 Q13177 Q5T1C6 Q6R327 Q96RU7 Q9BPZ7 Q9BVC4 Q9UKW4 Q9Y243	AKT1 AKT2 AKT3 C20orf97 CALM CALM1 CAM CAM1 CAV CAV1 CDH5 CTMP CTNNA1 CTNNB CTNNB1 CTNND1 CTNNG DP3 FRAP FRAP1 FRAP2 GBL HSP90A HSP90AA1 HSPC1 HSPCA JUP KIAA0384 KIAA1999 LST8 M MAPKAP1 MIP1 MLST8 MTOR N NIPK NOS3 OPHN3 PAK1 PAK2 PAK3 PDK1 PDPK1 PKB PKBG PROTOR1 PRR5 RAC RAC1 RAFT1 RAPT1 RICTOR SIN1 SKIP3 TC25 THEM4 TRB3 TRIB3 VAV VAV1 VAV2 VAV3	Homo sapiens (human)

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