Signaling by moderate kinase activity BRAF mutants
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- APBB1IP
- ARAF
- ARAF1
- ARB2
- ARR1
- ARR2
- ARRB1
- ARRB2
- BRAF
- BRAF1
- BRAP
- CALM
- CALM1
- CAM
- CAM1
- CAM2
- CAMK
- CAMK-II
- CAMK2
- CAMK2A
- CAMK2B
- CAMK2D
- CAMK2G
- CAMKA
- CAMKB
- CAMKD
- CAMKG
- CNK1
- CNK2
- CNKSR1
- CNKSR2
- CSK
- CTAK1
- EMK2
- ERK1
- ERK2
- F8VWF
- FGA
- FGB
- FGG
- FN
- FN1
- GP2B
- GP3A
- HRAS
- HRAS1
- IQGAP1
- ITGA2B
- ITGAB
- ITGB3
- JAK2
- KIAA0051
- KIAA0902
- KIAA0968
- KIAA1027
- KRAS
- KRAS2
- KREV1
- KSR
- KSR1
- KSR2
- MAP2K1
- MAP2K2
- MAP3K11
- MAPK1
- MAPK3
- MARK3
- MEK1
- MEK2
- MKK2
- MLK3
- NRAS
- PBP
- PEBP
- PEBP1
- PHB
- PHB1
- PKS
- PKS2
- PREL1
- PRKM1
- PRKM2
- PRKM3
- PRKMK1
- PRKMK2
- PTK1
- RAF
- RAF1
- RAFB1
- RAP1A
- RAP1B
- RARP1
- RASK2
- RIAM
- RNF52
- SPRK
- SRC
- SRC1
- TLN
- TLN1
- VCL
- VWF
- YWHAB
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Signaling by membrane-tethered fusions of PDGFRA or PDGFRB
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- ANKRD15
- BIN2
- BRAP1
- ETV6
- FLK1
- GOLGA4
- KANK
- KANK1
- KDR
- KIAA0172
- TEL
- TEL1
- VEGFR2
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Signaling by kinase domain mutants of KIT
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Signaling by juxtamembrane domain KIT mutants
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Signaling by high-kinase activity BRAF mutants
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- APBB1IP
- ARAF
- ARAF1
- ARB2
- ARR1
- ARR2
- ARRB1
- ARRB2
- BRAF
- BRAF1
- CNK1
- CNK2
- CNKSR1
- CNKSR2
- CSK
- CTAK1
- EMK2
- ERK1
- ERK2
- F8VWF
- FGA
- FGB
- FGG
- FN
- FN1
- GP2B
- GP3A
- HRAS
- HRAS1
- IQGAP1
- ITGA2B
- ITGAB
- ITGB3
- KIAA0051
- KIAA0902
- KIAA1027
- KREV1
- KSR
- KSR1
- KSR2
- MAP2K1
- MAP2K2
- MAPK1
- MAPK3
- MARK3
- MEK1
- MEK2
- MKK2
- NRAS
- PBP
- PEBP
- PEBP1
- PKS
- PKS2
- PREL1
- PRKM1
- PRKM2
- PRKM3
- PRKMK1
- PRKMK2
- RAF
- RAF1
- RAFB1
- RAP1A
- RAP1B
- RARP1
- RIAM
- SRC
- SRC1
- TLN
- TLN1
- VCL
- VWF
- YWHAB
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Signaling by extracellular domain mutants of KIT
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Signaling by cytosolic PDGFRA and PDGFRB fusion proteins
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- FIP1
- FIP1L1
- KIAA1449
- RHE
- STRN
- UAF1
- WDR48
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Signaling by cytosolic FGFR1 fusion mutants
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- APRF
- BCR
- BCR1
- CD245
- CEP43
- CFIM68
- CPSF6
- CUTL1
- CUX1
- D22S11
- FGFR1OP
- FGFR1OP2
- FIM
- FOP
- GAB2
- GCF2
- GRB1
- KIAA0216
- KIAA0571
- LRRFIP1
- MYO18A
- MYSPDZ
- PIK3CA
- PIK3R1
- RAMP
- RNF82
- STAT1
- STAT3
- STAT5
- STAT5A
- STAT5B
- TIAF1
- TIF1
- TIF1A
- TRIM24
- TRIP
- ZMYM2
- ZNF198
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Signaling by activated point mutants of FGFR3
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- FGF1
- FGF16
- FGF18
- FGF2
- FGF20
- FGF23
- FGF4
- FGF9
- FGFA
- FGFB
- FGFR3
- HST
- HSTF1
- HYPF
- JTK4
- KS3
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Signaling by activated point mutants of FGFR1
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- BFGFR
- CEK
- FGF1
- FGF2
- FGF20
- FGF23
- FGF4
- FGF6
- FGF9
- FGFA
- FGFB
- FGFBR
- FGFR1
- FLG
- FLT2
- HBGFR
- HST
- HST2
- HSTF1
- HSTF2
- HYPF
- KS3
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Signaling by VEGF
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Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
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- CILP
- IBP1
- IGF1
- IGF1R
- IGF2
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Signaling by TCF7L2 mutants
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- CTBP
- CTBP1
- CTBP2
- TCF4
- TCF7L2
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Signaling by SCF-KIT
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- APRF
- CHEK1
- CHK1
- CLG4B
- CMA1
- CYH
- CYM
- FER
- FES
- FMI
- FPS
- FYN
- GAB2
- GADS
- GRAP
- GRAP2
- GRB1
- GRB10
- GRB2L
- GRB7
- GRBIR
- GRID
- HRAS
- HRAS1
- JAK2
- JTK8
- KIAA0207
- KIAA0571
- KIT
- LCK
- LYN
- MMP9
- NRAS
- PCP2
- PIK3CA
- PIK3R1
- PIK3R2
- PIK3R3
- PKCA
- PRKACA
- PRKCA
- PSCTK4
- PTP2C
- PTPN11
- PTPRO
- PTPRU
- RAC1
- SCFR
- SHPTP2
- SOS1
- STAT1
- STAT3
- STAT5
- STAT5A
- STAT5B
- TC25
- TEC
- TYK3
- VAV
- VAV1
- YES
- YES1
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Signaling by Retinoic Acid
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- Carnitine O-palmitoyltransferase 1, liver isoform
- Carnitine O-palmitoyltransferase 1, muscle isoform
- Cellular retinoic acid-binding protein 2
- Dihydrolipoyl dehydrogenase, mitochondrial
- Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial
- Fatty acid-binding protein 5
- Peroxisome proliferator-activated receptor delta
- Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
- Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial
- Pyruvate dehydrogenase E1 component subunit beta, mitochondrial
- Pyruvate dehydrogenase protein X component, mitochondrial
- Retinoic acid receptor RXR-alpha
- Retinoic acid receptor RXR-beta
- Retinoic acid receptor RXR-gamma
- Retinoic acid receptor alpha
- Retinoic acid receptor beta
- Retinoic acid receptor gamma
- [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial
- [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial
- [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial
- [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial
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- CPT1
- CPT1A
- CPT1B
- CRABP2
- DLAT
- DLD
- DLTA
- FABP5
- GCSL
- HAP
- KIAA1670
- LAD
- NR1B1
- NR1B2
- NR1B3
- NR1C2
- NR2B1
- NR2B2
- NR2B3
- PDHA1
- PDHA2
- PDHAL
- PDHB
- PDHK1
- PDHK2
- PDHK3
- PDHK4
- PDHX
- PDK1
- PDK2
- PDK3
- PDK4
- PDX1
- PHE1A
- PHE1B
- PHE3
- PPARB
- PPARD
- RARA
- RARB
- RARG
- RXRA
- RXRB
- RXRG
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Signaling by ROBO receptors
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- CXCL12
- CXCR4
- DUTT1
- ENAH
- EVL
- FLRT3
- GPC1
- KIAA0813
- KIAA0814
- KIAA1469
- KIAA1568
- MEGF4
- MEGF5
- MENA
- NRP
- NRP1
- PFN1
- PFN2
- RNB6
- ROBO1
- ROBO2
- SDF1
- SDF1A
- SDF1B
- SLIL1
- SLIL2
- SLIL3
- SLIT1
- SLIT2
- SLIT3
- VASP
- VEGF165R
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Signaling by RNF43 mutants
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- C2orf31
- FZD4
- FZD5
- FZD6
- FZD8
- LR3
- LRP5
- LRP6
- LRP7
- RNF43
- WNT3A
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Signaling by RAS GTPase mutants
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- HRAS
- HRAS1
- KRAS
- KRAS2
- NRAS
- RASK2
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Signaling by RAS GAP mutants
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- HRAS
- HRAS1
- KRAS
- KRAS2
- NRAS
- RASK2
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Signaling by RAF1 mutants
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- APBB1IP
- ARAF
- ARAF1
- ARB2
- ARR1
- ARR2
- ARRB1
- ARRB2
- BRAF
- BRAF1
- CALM
- CALM1
- CAM
- CAM1
- CAM2
- CAMK
- CAMK-II
- CAMK2
- CAMK2A
- CAMK2B
- CAMK2D
- CAMK2G
- CAMKA
- CAMKB
- CAMKD
- CAMKG
- CNK1
- CNK2
- CNKSR1
- CNKSR2
- CSK
- CTAK1
- EMK2
- ERK1
- ERK2
- F8VWF
- FGA
- FGB
- FGG
- FN
- FN1
- GP2B
- GP3A
- HRAS
- HRAS1
- IQGAP1
- ITGA2B
- ITGAB
- ITGB3
- JAK2
- KIAA0051
- KIAA0902
- KIAA0968
- KIAA1027
- KREV1
- KSR
- KSR1
- KSR2
- MAP2K1
- MAP2K2
- MAPK1
- MAPK3
- MARK3
- MEK1
- MEK2
- MKK2
- NRAS
- PKS
- PKS2
- PREL1
- PRKM1
- PRKM2
- PRKM3
- PRKMK1
- PRKMK2
- RAF
- RAF1
- RAFB1
- RAP1A
- RAP1B
- RARP1
- RIAM
- SRC
- SRC1
- TLN
- TLN1
- VCL
- VWF
- YWHAB
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Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants
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- APRF
- GRB1
- HRAS
- HRAS1
- NRAS
- PDGFR2
- PDGFRA
- PIK3C1
- PIK3CA
- PIK3CB
- PIK3R1
- PIK3R2
- RHEPDGFRA
- SOS1
- STAT1
- STAT3
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Signaling by PDGFRA extracellular domain mutants
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- APRF
- GRB1
- HRAS
- HRAS1
- NRAS
- PDGFR2
- PDGFRA
- PIK3C1
- PIK3CA
- PIK3CB
- PIK3R1
- PIK3R2
- RHEPDGFRA
- SOS1
- STAT1
- STAT3
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Signaling by PDGF
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- BNSP
- COL29A1
- COL4A1
- COL4A2
- COL4A3
- COL4A4
- COL4A5
- COL6A1
- COL6A2
- COL6A3
- COL6A5
- COL6A6
- COL9A1
- COL9A2
- COL9A3
- FUR
- FURIN
- IEGF
- OPN
- PACE
- PCSK3
- PDGF2
- PDGFB
- PDGFD
- PDGFR
- PDGFR1
- PDGFR2
- PDGFRA
- PDGFRB
- PLAT
- PLG
- PTPN12
- RHEPDGFRA
- SCDGFB
- SIS
- SPP1
- THBS1
- THBS2
- THBS3
- THBS4
- TSP
- TSP1
- TSP2
- TSP3
- TSP4
- VWA4
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Signaling by NTRK3 (TRKC)
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- GLEPP1
- NTF3
- NTRK3
- PTPRO
- PTPRS
- PTPU2
- TRKC
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Signaling by NODAL
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- ACVR1B
- ACVR1C
- ACVR2
- ACVR2A
- ACVR2B
- ACVRLK4
- ALK4
- ALK7
- CER1
- CER2
- CFC1
- CKTSF1B3
- CRIPTO
- CRIPTO-1
- CRIPTO-3
- CRIPTO3
- DAND4
- DAND5
- DPC4
- DRAP1
- EBAF
- ERK1
- ERK2
- FAST1
- FAST2
- FKHRL1
- FOXH1
- FOXO3
- FOXO3A
- FUR
- FURIN
- GDF1
- GREM3
- LEFTA
- LEFTB
- LEFTY1
- LEFTY2
- LEFTYA
- LEFTYB
- MADH2
- MADH3
- MADH4
- MADR2
- MAPK1
- MAPK3
- NODAL
- PACE
- PACE4
- PCSK3
- PCSK6
- PRKM1
- PRKM2
- PRKM3
- SMAD2
- SMAD3
- SMAD4
- SP1
- TDGF1
- TDGF1P3
- TDGF2
- TDGF3
- TGFB4
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